333:
310:
207:
232:
2873:
2903:
2888:
584:
339:
238:
40:
2804:
1810:
De
Crescenzo G, Pham PL, Durocher Y, O'Connor-McCourt MD (May 2003). "Transforming growth factor-beta (TGF-beta) binding to the extracellular domain of the type II TGF-beta receptor: receptor capture on a biosensor surface using a new coiled-coil capture system demonstrates that avidity contributes
2568:
Djonov V, Ball RK, Graf S, Mottaz AE, Arnold AM, Flanders K, Studer UE, Merz VW (May 1997). "Transforming growth factor-beta 3 is expressed in nondividing basal epithelial cells in normal human prostate and benign prostatic hyperplasia, and is no longer detectable in prostate carcinoma".
66:
2754:
Mori T, Kawara S, Shinozaki M, Hayashi N, Kakinuma T, Igarashi A, Takigawa M, Nakanishi T, Takehara K (Oct 1999). "Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model".
2379:
Zhao Y, Chegini N, Flanders KC (Oct 1994). "Human fallopian tube expresses transforming growth factor (TGF beta) isoforms, TGF beta type I-III receptor messenger ribonucleic acid and protein, and contains TGF beta-binding sites".
2247:
Kaartinen V, Voncken JW, Shuler C, Warburton D, Bu D, Heisterkamp N, Groffen J (Dec 1995). "Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction".
1766:
Kaartinen V, Voncken JW, Shuler C, Warburton D, Bu D, Heisterkamp N, Groffen J (Dec 1995). "Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction".
2538:
Ambros RA, Kallakury BV, Malfetano JH, Mihm MC (Oct 1996). "Cytokine, cell adhesion receptor, and tumor suppressor gene expression in vulvar squamous carcinoma: correlation with prominent fibromyxoid stromal response".
4005:
2349:
Rampazzo A, Nava A, Danieli GA, Buja G, Daliento L, Fasoli G, Scognamiglio R, Corrado D, Thiene G (Jun 1994). "The gene for arrhythmogenic right ventricular cardiomyopathy maps to chromosome 14q23-q24".
2225:
Barton DE, Foellmer BE, Du J, Tamm J, Derynck R, Francke U (1989). "Chromosomal mapping of genes for transforming growth factors beta 2 and beta 3 in man and mouse: dispersion of TGF-beta gene family".
2872:
2316:"The soluble exoplasmic domain of the type II transforming growth factor (TGF)-beta receptor. A heterogeneously glycosylated protein with high affinity and selectivity for TGF-beta ligands"
3998:
2025:
346:
245:
2641:
Lidral AC, Romitti PA, Basart AM, Doetschman T, Leysens NJ, Daack-Hirsch S, Semina EV, Johnson LR, Machida J, Burds A, Parnell TJ, Rubenstein JL, Murray JC (Aug 1998).
2285:
Nishida K, Sotozono C, Adachi W, Yamamoto S, Yokoi N, Kinoshita S (Mar 1995). "Transforming growth factor-beta 1, -beta 2 and -beta 3 mRNA expression in human cornea".
3991:
1979:
Ferguson MW, Duncan J, Bond J, Bush J, Durani P, So K, Taylor L, Chantrey J, Mason T, James G, Laverty H, Occleston NL, Sattar A, Ludlow A, O'Kane S (Apr 2009).
1661:
Herpin A, Lelong C, Favrel P (May 2004). "Transforming growth factor-beta-related proteins: an ancestral and widespread superfamily of cytokines in metazoans".
3482:
2943:
2902:
2686:"Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily"
1891:"Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily"
3243:
2964:
2887:
1406:
1097:
1078:
168:
3380:
3374:
3369:
3359:
3354:
3349:
3344:
3339:
2608:"Transforming growth factor-beta, transforming growth factor-beta receptor II, and p27Kip1 expression in nontumorous and neoplastic human pituitaries"
3515:
5563:
3740:
5621:
2852:
1577:
1559:
3941:
3936:
3931:
3196:
1846:
Hart PJ, Deep S, Taylor AB, Shu Z, Hinck CS, Hinck AP (Mar 2002). "Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex".
1456:
in mammals, by also regulating cell adhesion and ECM formation in this tissue, and controls wound healing by regulating the movements of
332:
3046:
2582:
2768:
1981:"Prophylactic administration of avotermin for improvement of skin scarring: three double-blind, placebo-controlled, phase I/II studies"
1731:
Dudas M, Nagy A, Laping NJ, Moustakas A, Kaartinen V (Feb 2004). "Tgf-beta3-induced palatal fusion is mediated by Alk-5/Smad pathway".
3923:
3288:
2454:"Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites"
1311:
1318:
309:
3543:
1418:
1932:"Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor"
2936:
1647:
5482:
4908:
4552:
4248:
4103:
3829:
3758:
3428:
3151:
2986:
1546:
1525:
3890:
3558:
2411:"Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor beta"
231:
206:
1542:
63:
5314:
5150:
5015:
4898:
4800:
4726:
4538:
4429:
4093:
3438:
3111:
3104:
3099:
3094:
3089:
1521:
5440:
5350:
5286:
5106:
4983:
4871:
4682:
4328:
4028:
4014:
3817:
3812:
3508:
3084:
3079:
3074:
3069:
3064:
3059:
148:
1452:
in both sides of the developing palate to fuse. TGF-β3 also plays an essential role in controlling the development of
139:, ARVD, ARVD1, RNHF, TGF-beta3, Transforming growth factor, beta 3, LDS5, transforming growth factor beta 3, TGF beta 3
3946:
3708:
2929:
1473:
1980:
345:
244:
5282:
5102:
4979:
4678:
4324:
4217:
4078:
3802:
3785:
3750:
3587:
3390:
3054:
1414:
338:
237:
5426:
4319:
4207:
3173:
2956:
2845:
3972:
3532:
3271:
3216:
3200:
1142:
156:
2800:
GeneReviews/NCBI/NIH/UW entry on
Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy, Autosomal Dominant
2721:"Assignment of transforming growth factor beta1 and beta3 and a third new ligand to the type I receptor ALK-1"
2182:
Derynck R, Lindquist PB, Lee A, Wen D, Tamm J, Graycar JL, Rhee L, Mason AJ, Miller DA, Coffey RJ (Dec 1988).
1600:"A "traffic control" role for TGFbeta3: orchestrating dermal and epidermal cell motility during wound healing"
5631:
3951:
3735:
3501:
1123:
2881:: Crystal Structure of the Human TGF-beta Type II Receptor Extracellular Domain in Complex with TGF-beta3
1402:
220:
2838:
2497:"The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding"
2142:
1696:
Taya Y, O'Kane S, Ferguson MW (Sep 1999). "Pathogenesis of cleft palate in TGF-beta3 knockout mice".
1437:
1394:
135:
2409:
Hildebrand A, Romarís M, Rasmussen LM, Heinegård D, Twardzik DR, Border WA, Ruoslahti E (Sep 1994).
5573:
3967:
3323:
3008:
2088:"Inhibition of translation of transforming growth factor-beta 3 mRNA by its 5' untranslated region"
1477:
1271:
1267:
1220:
1216:
4767:
4378:
4281:
5523:
5398:
4161:
4020:
3398:
3187:
2780:
2594:
2273:
2008:
1871:
1792:
180:
5355:
5198:
5037:
4752:
1275:
1241:
1212:
4956:
4857:
4645:
4640:
4610:
4605:
4505:
5626:
5548:
4625:
4088:
3418:
2978:
2810:
2772:
2742:
2707:
2672:
2629:
2586:
2556:
2526:
2483:
2440:
2397:
2367:
2337:
2302:
2265:
2235:
2213:
2170:
2117:
2074:
2000:
1961:
1912:
1863:
1828:
1784:
1748:
1713:
1678:
1629:
1379:
128:
56:
4847:
4772:
4595:
4495:
4383:
4286:
4136:
2805:
OMIM entries on
Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy, Autosomal Dominant
5568:
5558:
4650:
4600:
4291:
4141:
3443:
3433:
3192:
2974:
2764:
2732:
2697:
2662:
2654:
2619:
2578:
2548:
2516:
2508:
2473:
2465:
2430:
2422:
2389:
2359:
2327:
2294:
2257:
2203:
2195:
2160:
2150:
2107:
2099:
2064:
2056:
1992:
1951:
1943:
1902:
1855:
1820:
1776:
1740:
1705:
1670:
1619:
1611:
1457:
953:
regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
425:
356:
300:
255:
4951:
4762:
4373:
4276:
4271:
583:
176:
5379:
5309:
5304:
5222:
5145:
5140:
5010:
5005:
4828:
4721:
4716:
4476:
4363:
4358:
4243:
3869:
3864:
3722:
3423:
2606:
Jin L, Qian X, Kulig E, Sanno N, Scheithauer BW, Kovacs K, Young WF, Lloyd RV (Aug 1997).
2131:"Identification of another member of the transforming growth factor type beta gene family"
1449:
400:
2921:
2146:
2026:
Renovo shares plummet 75% as scar revision product
Juvista fails to meet study endpoints
3983:
3327:
2952:
2667:
2642:
2624:
2607:
2521:
2496:
2478:
2453:
2435:
2410:
2199:
1624:
1599:
1489:
39:
2208:
2183:
2165:
2130:
2112:
2087:
2069:
2044:
1996:
1956:
1931:
1824:
1012:
1007:
1002:
997:
992:
987:
982:
977:
972:
967:
962:
957:
952:
947:
942:
937:
932:
927:
922:
917:
912:
907:
902:
897:
892:
887:
882:
877:
872:
867:
862:
857:
852:
847:
842:
837:
832:
827:
822:
817:
812:
807:
802:
797:
792:
787:
782:
777:
772:
767:
762:
746:
741:
736:
731:
726:
721:
716:
711:
706:
701:
696:
691:
686:
670:
665:
660:
655:
650:
645:
640:
635:
630:
625:
5615:
5533:
4126:
3524:
2819:
2552:
1433:
1398:
612:
2784:
2598:
2277:
2012:
1875:
1796:
5553:
4936:
4931:
4620:
4580:
4575:
4151:
1445:
418:
197:
160:
833:
negative regulation of transforming growth factor beta receptor signaling pathway
184:
5543:
5241:
4941:
4585:
3453:
3413:
1744:
1582:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1564:
National Center for
Biotechnology Information, U.S. National Library of Medicine
2135:
Proceedings of the
National Academy of Sciences of the United States of America
501:
5583:
5494:
5490:
5486:
5276:
5096:
4920:
4916:
4912:
4615:
4564:
4560:
4556:
4423:
4260:
4256:
4252:
4201:
4115:
4111:
4107:
4067:
3773:
3768:
3763:
3309:
3001:
2996:
2991:
2799:
2495:
Mittl PR, Priestle JP, Cox DA, McMaster G, Cerletti N, Grütter MG (Jul 1996).
2393:
2298:
1674:
317:
214:
164:
1947:
5476:
5472:
5463:
5373:
5369:
5340:
5272:
5268:
5216:
5212:
5188:
5092:
5088:
5055:
5051:
4893:
4852:
4635:
4533:
4500:
4470:
4466:
4447:
4419:
4415:
4212:
4197:
4193:
4073:
4063:
4059:
3874:
3730:
3146:
2737:
2720:
2155:
1709:
1042:
561:
439:
384:
371:
283:
270:
172:
5449:
4880:
2776:
2746:
2583:
10.1002/(SICI)1097-0045(19970501)31:2<103::AID-PROS5>3.0.CO;2-O
2512:
2332:
2315:
2078:
2004:
1965:
1867:
1832:
1752:
1717:
1682:
1633:
1598:
Bandyopadhyay B, Fan J, Guan S, Li Y, Chen M, Woodley DT, Li W (Mar 2006).
978:
negative regulation of vascular associated smooth muscle cell proliferation
2769:
10.1002/(SICI)1097-4652(199910)181:1<153::AID-JCP16>3.0.CO;2-K
2711:
2702:
2685:
2676:
2633:
2590:
2560:
2530:
2487:
2469:
2444:
2401:
2371:
2363:
2341:
2306:
2269:
2239:
2217:
2174:
2121:
2103:
1916:
1907:
1890:
1788:
1615:
1358:
1353:
17:
5600:
3684:
1422:
1410:
1390:
1342:
1187:
1168:
2314:
Lin HY, Moustakas A, Knaus P, Wells RG, Henis YI, Lodish HF (Feb 1995).
5538:
5528:
5468:
5365:
5264:
5208:
5084:
5047:
4462:
4411:
4189:
4055:
3859:
3798:
3408:
3403:
2824:
2814:
2261:
1780:
1426:
1374:
1154:
1109:
2426:
968:
positive regulation of pathway-restricted SMAD protein phosphorylation
105:
101:
97:
93:
89:
85:
5589:
5387:
5383:
5251:
5230:
5226:
5066:
4836:
4832:
4630:
4484:
4480:
3466:
3365:
3335:
3281:
3276:
3253:
3248:
3238:
3231:
3226:
2911:: HUMAN TRANSFORMING GROWTH FACTOR BETA 3, CRYSTALLIZED FROM PEG 4000
2060:
2045:"Epithelial-mesenchymal transition and its implications for fibrosis"
1930:
Rotzer D, Roth M, Lutz M, Lindemann D, Sebald W, Knaus P (Feb 2001).
1461:
1444:
development. Without TGF-β3, mammals develop a deformity known as a
1441:
1326:
1064:
2896:: HUMAN TRANSFORMING GROWTH FACTOR-BETA 3, CRYSTALLIZED FROM DIOXANE
2643:"Association of MSX1 and TGFB3 with nonsyndromic clefting in humans"
4665:
4306:
2658:
1859:
5518:
5450:
5408:
5345:
5193:
5182:
5178:
5134:
5130:
5126:
4999:
4967:
4966:
4902:
4881:
4818:
4812:
4746:
4710:
4706:
4702:
4546:
4542:
4520:
4452:
4441:
4352:
4348:
4237:
4233:
4082:
3913:
3908:
3903:
3898:
3854:
3849:
3844:
3839:
3703:
3698:
3693:
3669:
3663:
3657:
3651:
3631:
3627:
3618:
3614:
3605:
3601:
3461:
3293:
3221:
3166:
3161:
3156:
3035:
3028:
3023:
3018:
2129:
ten Dijke P, Hansen P, Iwata KK, Pieler C, Foulkes JG (Jul 1988).
3493:
1027:
1023:
5334:
5330:
5326:
5322:
5318:
5298:
5294:
5290:
5174:
5170:
5166:
5162:
5158:
5154:
5122:
5118:
5114:
5110:
5031:
5027:
5023:
5019:
4995:
4991:
4987:
4808:
4804:
4782:
4742:
4738:
4734:
4730:
4698:
4694:
4690:
4686:
4660:
4515:
4437:
4433:
4393:
4344:
4340:
4336:
4332:
4301:
4229:
4225:
4221:
4171:
4097:
4037:
3623:
3610:
3597:
3575:
3571:
3567:
3562:
3554:
3141:
3136:
3131:
3126:
3121:
3116:
3013:
1453:
1383:
152:
3987:
3497:
2925:
2834:
592:
5409:
2830:
2452:
López-Casillas F, Payne HM, Andres JL, Massagué J (Feb 1994).
2809:
Overview of all the structural information available in the
2184:"A new type of transforming growth factor-beta, TGF-beta 3"
943:
positive regulation of epithelial to mesenchymal transition
903:
transforming growth factor beta receptor signaling pathway
928:
positive regulation of transcription by RNA polymerase II
626:
type III transforming growth factor beta receptor binding
666:
type II transforming growth factor beta receptor binding
408:
5413:
4015:
1648:"Entrez Gene: TGFB3 transforming growth factor, beta 3"
1405:. It belongs to a large family of cytokines called the
933:
positive regulation of SMAD protein signal transduction
636:
type I transforming growth factor beta receptor binding
4783:
4661:
4516:
4394:
4302:
4172:
4042:
4038:
2086:
Arrick BA, Lee AL, Grendell RL, Derynck R (Sep 1991).
1472:
Transforming growth factor, beta 3 has been shown to
1432:
TGF-β3 is believed to regulate molecules involved in
888:
negative regulation of macrophage cytokine production
573:
2382:
The
Journal of Clinical Endocrinology and Metabolism
1003:
negative regulation of cell population proliferation
998:
positive regulation of cell population proliferation
773:
positive regulation of collagen biosynthetic process
5508:
5448:
5439:
5407:
5250:
5065:
4965:
4879:
4870:
4781:
4659:
4514:
4392:
4300:
4170:
4036:
4027:
3960:
3922:
3889:
3826:
3795:
3784:
3749:
3721:
3679:
3640:
3584:
3540:
3531:
3475:
3452:
3389:
3322:
3302:
3264:
3209:
3186:
3044:
2972:
2963:
1289:
1260:
1234:
1205:
973:
positive regulation of transcription, DNA-templated
4787:
4398:
4176:
1538:
1536:
1534:
1517:
1515:
1513:
938:positive regulation of tight junction disassembly
355:
254:
5252:
5067:
2541:International Journal of Gynecological Pathology
651:transforming growth factor beta receptor binding
5071:
768:negative regulation of neuron apoptotic process
27:Protein-coding gene in the species Homo sapiens
1593:
1591:
1543:GRCm38: Ensembl release 89: ENSMUSG00000021253
3999:
3509:
2937:
2846:
8:
2684:Barbara NP, Wrana JL, Letarte M (Jan 1999).
1889:Barbara NP, Wrana JL, Letarte M (Jan 1999).
948:positive regulation of stress fiber assembly
2823:(Transforming growth factor beta-3) at the
1522:GRCh38: Ensembl release 89: ENSG00000119699
1407:Transforming growth factor beta superfamily
1013:regulation of cell population proliferation
5445:
4876:
4033:
4006:
3992:
3984:
3792:
3537:
3516:
3502:
3494:
3206:
2969:
2944:
2930:
2922:
2853:
2839:
2831:
2719:Lux A, Attisano L, Marchuk DA (Apr 1999).
1038:
908:positive regulation of filopodium assembly
793:positive regulation of bone mineralization
608:
396:
295:
192:
74:
2736:
2701:
2666:
2623:
2520:
2477:
2434:
2331:
2207:
2164:
2154:
2111:
2068:
1955:
1906:
1811:significantly to high affinity binding".
1623:
993:regulation of signaling receptor activity
1663:Developmental and Comparative Immunology
958:positive regulation of apoptotic process
868:ossification involved in bone remodeling
863:positive regulation of protein secretion
747:collagen-containing extracellular matrix
742:intracellular membrane-bounded organelle
2868:
1509:
661:transforming growth factor beta binding
1440:(ECM) formation during the process of
813:response to laminar fluid shear stress
29:
2049:The Journal of Clinical Investigation
360:
321:
316:
259:
218:
213:
7:
1389:It is a type of protein, known as a
913:positive regulation of cell division
798:embryonic neurocranium morphogenesis
2725:The Journal of Biological Chemistry
2690:The Journal of Biological Chemistry
2320:The Journal of Biological Chemistry
1895:The Journal of Biological Chemistry
646:protein heterodimerization activity
5516:Endogenous antagonists/inhibitors:
2647:American Journal of Human Genetics
2200:10.1002/j.1460-2075.1988.tb03257.x
2043:Kalluri R, Neilson EG (Dec 2003).
1419:growth and differentiation factors
1286:
1257:
1231:
1202:
1178:
1159:
1133:
1114:
1088:
1069:
578:
496:
434:
413:
25:
2612:The American Journal of Pathology
1377:that in humans is encoded by the
1371:Transforming growth factor beta-3
2901:
2886:
2871:
2553:10.1097/00004347-199610000-00004
788:SMAD protein signal transduction
582:
344:
337:
331:
308:
243:
236:
230:
205:
38:
3830:Relaxin family peptide hormones
2965:TGF beta superfamily of ligands
1448:. This is caused by failure of
778:cell-cell junction organization
763:regulation of apoptotic process
4292:ML-347 (LDN-193719, VU0469381)
4142:ML-347 (LDN-193719, VU0469381)
3112:Growth differentiation factors
2757:Journal of Cellular Physiology
2092:Molecular and Cellular Biology
1500:) failed in Phase III trials.
828:in utero embryonic development
593:More reference expression data
562:More reference expression data
1:
1997:10.1016/S0140-6736(09)60322-6
1825:10.1016/S0022-2836(03)00360-7
329:
228:
5622:Genes on human chromosome 14
1813:Journal of Molecular Biology
1492:, human recombinant TGF-β3 (
1488:After successful phase I/II
1008:secondary palate development
878:frontal suture morphogenesis
843:salivary gland morphogenesis
722:platelet alpha granule lumen
4631:RepSox (E-616452, SJN-2511)
3055:Bone morphogenetic proteins
2458:The Journal of Cell Biology
1745:10.1016/j.ydbio.2003.10.007
1604:The Journal of Cell Biology
1415:Bone morphogenetic proteins
898:digestive tract development
5648:
3803:Insulin-like growth factor
783:regulation of MAPK cascade
4621:Galunisertib (LY-2157299)
2866:
2394:10.1210/jcem.79.4.7962292
2299:10.3109/02713689509033520
1848:Nature Structural Biology
1675:10.1016/j.dci.2003.09.007
1578:"Mouse PubMed Reference:"
1560:"Human PubMed Reference:"
1357:
1352:
1348:
1341:
1325:
1306:
1293:
1264:
1253:
1238:
1209:
1198:
1185:
1181:
1166:
1162:
1153:
1140:
1136:
1121:
1117:
1108:
1095:
1091:
1076:
1072:
1063:
1048:
1041:
1037:
1021:
893:lung alveolus development
848:mammary gland development
671:identical protein binding
611:
607:
590:
581:
572:
559:
508:
499:
446:
437:
407:
399:
395:
378:
365:
328:
307:
298:
294:
277:
264:
227:
204:
195:
191:
146:
143:
133:
126:
121:
82:
77:
60:
55:
50:
46:
37:
32:
5569:Thrombospondin 1 (THBS1)
5351:Osteogenin (BMP3, BMP3A)
3272:Activin type 2 receptors
3217:Activin type 1 receptors
2352:Human Molecular Genetics
1312:Chr 14: 75.96 – 75.98 Mb
803:response to progesterone
3643:FGF homologous factors:
2738:10.1074/jbc.274.15.9984
2415:The Biochemical Journal
2156:10.1073/pnas.85.13.4715
1710:10.1242/dev.126.17.3869
1464:cells in injured skin.
1393:, which is involved in
1319:Chr 12: 86.1 – 86.13 Mb
524:internal carotid artery
512:external carotid artery
4768:Dorsomorphin (BML-275)
4379:Dorsomorphin (BML-275)
4282:Dorsomorphin (BML-275)
3174:Anti-müllerian hormone
2957:TGFβ signaling pathway
2513:10.1002/pro.5560050705
2333:10.1074/jbc.270.6.2747
1948:10.1093/emboj/20.3.480
873:uterine wall breakdown
823:platelet degranulation
656:growth factor activity
362:12 D2|12 40.09 cM
2703:10.1074/jbc.274.2.584
2470:10.1083/jcb.124.4.557
2104:10.1128/mcb.11.9.4306
1908:10.1074/jbc.274.2.584
1733:Developmental Biology
1616:10.1083/jcb.200507111
1496:, planned trade name
1409:, which includes the
983:BMP signaling pathway
883:inner ear development
323:Chromosome 12 (mouse)
221:Chromosome 14 (human)
4018:receptor superfamily
3924:Vascular endothelial
2287:Current Eye Research
1438:extracellular matrix
1395:cell differentiation
923:detection of hypoxia
858:response to estrogen
732:extracellular region
692:extracellular matrix
470:smooth muscle tissue
78:List of PDB id codes
51:Available structures
5586:(against myostatin)
3009:Activin and inhibin
2364:10.1093/hmg/3.6.959
2147:1988PNAS...85.4715T
1478:TGF beta receptor 2
963:response to hypoxia
737:extracellular space
454:canal of the cervix
5592:(against endoglin)
4949:Kinase inhibitors:
4845:Kinase inhibitors:
4760:Kinase inhibitors:
4593:Kinase inhibitors:
4493:Kinase inhibitors:
4371:Kinase inhibitors:
4269:Kinase inhibitors:
4134:Kinase inhibitors:
3188:TGF beta receptors
2262:10.1038/ng1295-415
2028:, 14 February 2011
1781:10.1038/ng1295-415
1143:ENSMUSG00000021253
918:face morphogenesis
756:Biological process
717:neuronal cell body
680:Cellular component
619:Molecular function
5609:
5608:
5504:
5503:
5435:
5434:
4866:
4865:
4159:Other inhibitors:
3981:
3980:
3885:
3884:
3717:
3716:
3491:
3490:
3391:Ligand inhibitors
3318:
3317:
3182:
3181:
2919:
2918:
2427:10.1042/bj3020527
2228:Oncogene Research
1991:(9671): 1264–74.
1484:Clinical research
1434:cellular adhesion
1368:
1367:
1364:
1363:
1337:
1336:
1302:
1301:
1283:
1282:
1249:
1248:
1228:
1227:
1194:
1193:
1175:
1174:
1149:
1148:
1130:
1129:
1104:
1103:
1085:
1084:
1033:
1032:
707:secretory granule
631:cytokine activity
603:
602:
599:
598:
568:
567:
555:
554:
528:lactiferous gland
493:
492:
478:periodontal fiber
391:
390:
290:
289:
185:TGFB3 - orthologs
117:
116:
113:
112:
61:Ortholog search:
16:(Redirected from
5639:
5452:
5446:
5415:
5411:
5396:Decoy receptors:
5341:Myostatin (GDF8)
5254:
5239:Decoy receptors:
5189:Myostatin (GDF8)
5073:
5069:
4969:
4883:
4877:
4789:
4785:
4667:
4663:
4522:
4518:
4448:Myostatin (GDF8)
4400:
4396:
4308:
4304:
4178:
4174:
4149:Decoy receptors:
4044:
4040:
4034:
4017:
4008:
4001:
3994:
3985:
3891:Platelet-derived
3833:
3806:
3793:
3687:
3645:
3591:
3548:
3538:
3518:
3511:
3504:
3495:
3207:
2970:
2946:
2939:
2932:
2923:
2905:
2890:
2875:
2855:
2848:
2841:
2832:
2788:
2750:
2740:
2715:
2705:
2680:
2670:
2637:
2627:
2602:
2564:
2534:
2524:
2491:
2481:
2448:
2438:
2405:
2375:
2345:
2335:
2310:
2281:
2243:
2221:
2211:
2188:The EMBO Journal
2178:
2168:
2158:
2125:
2115:
2082:
2072:
2061:10.1172/JCI20530
2029:
2023:
2017:
2016:
1976:
1970:
1969:
1959:
1936:The EMBO Journal
1927:
1921:
1920:
1910:
1886:
1880:
1879:
1843:
1837:
1836:
1807:
1801:
1800:
1763:
1757:
1756:
1728:
1722:
1721:
1693:
1687:
1686:
1658:
1652:
1651:
1644:
1638:
1637:
1627:
1595:
1586:
1585:
1574:
1568:
1567:
1556:
1550:
1540:
1529:
1519:
1450:epithelial cells
1350:
1349:
1321:
1314:
1297:
1287:
1278:
1258:
1254:RefSeq (protein)
1244:
1232:
1223:
1203:
1179:
1160:
1134:
1115:
1089:
1070:
1039:
988:cell development
808:female pregnancy
609:
595:
586:
579:
564:
504:
502:Top expressed in
497:
474:body of pancreas
466:cartilage tissue
442:
440:Top expressed in
435:
414:
397:
387:
374:
363:
348:
341:
335:
324:
312:
296:
286:
273:
262:
247:
240:
234:
223:
209:
193:
187:
138:
131:
108:
75:
69:
48:
47:
42:
30:
21:
5647:
5646:
5642:
5641:
5640:
5638:
5637:
5636:
5612:
5611:
5610:
5605:
5524:Cerberus (CER1)
5500:
5431:
5403:
5310:Eptotermin alfa
5305:Dibotermin alfa
5246:
5146:Eptotermin alfa
5141:Dibotermin alfa
5061:
5011:Eptotermin alfa
5006:Dibotermin alfa
4961:
4862:
4777:
4722:Eptotermin alfa
4717:Dibotermin alfa
4655:
4510:
4388:
4364:Eptotermin alfa
4359:Dibotermin alfa
4296:
4244:Eptotermin alfa
4166:
4023:
4012:
3982:
3977:
3956:
3918:
3881:
3827:
3822:
3796:
3787:
3780:
3745:
3723:EGF-like domain
3713:
3680:
3675:
3641:
3636:
3585:
3580:
3541:
3527:
3522:
3492:
3487:
3471:
3448:
3385:
3314:
3298:
3260:
3190:
3178:
3040:
2987:TGF beta family
2959:
2950:
2920:
2915:
2912:
2906:
2897:
2891:
2882:
2876:
2862:
2859:
2796:
2791:
2753:
2731:(15): 9984–92.
2718:
2683:
2640:
2605:
2567:
2537:
2501:Protein Science
2494:
2451:
2408:
2378:
2348:
2313:
2284:
2250:Nature Genetics
2246:
2224:
2194:(12): 3737–43.
2181:
2128:
2085:
2055:(12): 1776–84.
2042:
2038:
2036:Further reading
2033:
2032:
2024:
2020:
1978:
1977:
1973:
1929:
1928:
1924:
1888:
1887:
1883:
1845:
1844:
1840:
1809:
1808:
1804:
1769:Nature Genetics
1765:
1764:
1760:
1730:
1729:
1725:
1704:(17): 3869–79.
1695:
1694:
1690:
1660:
1659:
1655:
1646:
1645:
1641:
1610:(7): 1093–105.
1597:
1596:
1589:
1576:
1575:
1571:
1558:
1557:
1553:
1541:
1532:
1520:
1511:
1506:
1486:
1470:
1359:View/Edit Mouse
1354:View/Edit Human
1317:
1310:
1307:Location (UCSC)
1295:
1274:
1270:
1266:
1240:
1219:
1215:
1211:
1124:ENSG00000119699
1017:
751:
702:plasma membrane
675:
641:protein binding
591:
560:
551:
546:
542:
538:
534:
532:ascending aorta
530:
526:
522:
518:
514:
500:
489:
484:
480:
476:
472:
468:
464:
460:
456:
452:
438:
382:
369:
361:
351:
350:
349:
342:
322:
299:Gene location (
281:
268:
260:
250:
249:
248:
241:
219:
196:Gene location (
147:
134:
127:
84:
62:
28:
23:
22:
15:
12:
11:
5:
5645:
5643:
5635:
5634:
5629:
5624:
5614:
5613:
5607:
5606:
5604:
5603:
5594:
5593:
5587:
5577:
5576:
5571:
5566:
5561:
5556:
5551:
5546:
5541:
5536:
5531:
5526:
5521:
5512:
5510:
5506:
5505:
5502:
5501:
5499:
5498:
5480:
5466:
5457:
5455:
5443:
5437:
5436:
5433:
5432:
5430:
5429:
5420:
5418:
5405:
5404:
5402:
5401:
5392:
5391:
5377:
5359:
5358:
5353:
5348:
5343:
5338:
5312:
5307:
5302:
5280:
5258:
5256:
5248:
5247:
5245:
5244:
5235:
5234:
5220:
5202:
5201:
5196:
5191:
5186:
5148:
5143:
5138:
5100:
5078:
5076:
5063:
5062:
5060:
5059:
5041:
5040:
5035:
5013:
5008:
5003:
4973:
4971:
4963:
4962:
4960:
4959:
4954:
4945:
4944:
4939:
4934:
4925:
4924:
4906:
4896:
4887:
4885:
4874:
4868:
4867:
4864:
4863:
4861:
4860:
4855:
4850:
4841:
4840:
4822:
4821:
4816:
4794:
4792:
4779:
4778:
4776:
4775:
4770:
4765:
4756:
4755:
4750:
4724:
4719:
4714:
4672:
4670:
4657:
4656:
4654:
4653:
4648:
4643:
4638:
4633:
4628:
4623:
4618:
4613:
4608:
4603:
4598:
4589:
4588:
4583:
4578:
4569:
4568:
4550:
4536:
4527:
4525:
4512:
4511:
4509:
4508:
4503:
4498:
4489:
4488:
4474:
4456:
4455:
4450:
4445:
4427:
4405:
4403:
4390:
4389:
4387:
4386:
4381:
4376:
4367:
4366:
4361:
4356:
4322:
4313:
4311:
4298:
4297:
4295:
4294:
4289:
4284:
4279:
4274:
4265:
4264:
4246:
4241:
4215:
4210:
4205:
4183:
4181:
4168:
4167:
4165:
4164:
4155:
4154:
4145:
4144:
4139:
4130:
4129:
4120:
4119:
4101:
4091:
4086:
4076:
4071:
4049:
4047:
4031:
4025:
4024:
4013:
4011:
4010:
4003:
3996:
3988:
3979:
3978:
3976:
3975:
3970:
3964:
3962:
3958:
3957:
3955:
3954:
3949:
3944:
3939:
3934:
3928:
3926:
3920:
3919:
3917:
3916:
3911:
3906:
3901:
3895:
3893:
3887:
3886:
3883:
3882:
3880:
3879:
3878:
3877:
3872:
3867:
3857:
3852:
3847:
3842:
3836:
3834:
3824:
3823:
3821:
3820:
3815:
3809:
3807:
3790:
3788:Relaxin family
3782:
3781:
3779:
3778:
3777:
3776:
3771:
3766:
3755:
3753:
3747:
3746:
3744:
3743:
3738:
3733:
3727:
3725:
3719:
3718:
3715:
3714:
3712:
3711:
3706:
3701:
3696:
3690:
3688:
3677:
3676:
3674:
3673:
3667:
3661:
3655:
3648:
3646:
3638:
3637:
3635:
3634:
3621:
3608:
3594:
3592:
3582:
3581:
3579:
3578:
3565:
3551:
3549:
3535:
3529:
3528:
3525:Growth factors
3523:
3521:
3520:
3513:
3506:
3498:
3489:
3488:
3486:
3485:
3479:
3477:
3473:
3472:
3470:
3469:
3464:
3458:
3456:
3450:
3449:
3447:
3446:
3441:
3436:
3431:
3426:
3421:
3416:
3411:
3406:
3401:
3395:
3393:
3387:
3386:
3384:
3383:
3378:
3372:
3363:
3357:
3352:
3347:
3342:
3332:
3330:
3320:
3319:
3316:
3315:
3313:
3312:
3306:
3304:
3300:
3299:
3297:
3296:
3291:
3286:
3285:
3284:
3279:
3268:
3266:
3262:
3261:
3259:
3258:
3257:
3256:
3251:
3241:
3236:
3235:
3234:
3229:
3224:
3213:
3211:
3204:
3184:
3183:
3180:
3179:
3177:
3176:
3171:
3170:
3169:
3164:
3159:
3154:
3149:
3147:Myostatin/GDF8
3144:
3139:
3134:
3129:
3124:
3119:
3109:
3108:
3107:
3102:
3097:
3092:
3087:
3082:
3077:
3072:
3067:
3062:
3051:
3049:
3042:
3041:
3039:
3038:
3033:
3032:
3031:
3026:
3021:
3016:
3006:
3005:
3004:
2999:
2994:
2983:
2981:
2967:
2961:
2960:
2953:Cell signaling
2951:
2949:
2948:
2941:
2934:
2926:
2917:
2916:
2914:
2913:
2907:
2900:
2898:
2892:
2885:
2883:
2877:
2870:
2867:
2864:
2863:
2860:
2858:
2857:
2850:
2843:
2835:
2829:
2828:
2807:
2802:
2795:
2794:External links
2792:
2790:
2789:
2751:
2716:
2681:
2659:10.1086/301956
2638:
2603:
2565:
2535:
2507:(7): 1261–71.
2492:
2449:
2406:
2388:(4): 1177–84.
2376:
2346:
2326:(6): 2747–54.
2311:
2282:
2244:
2222:
2179:
2141:(13): 4715–9.
2126:
2098:(9): 4306–13.
2083:
2039:
2037:
2034:
2031:
2030:
2018:
1971:
1922:
1881:
1860:10.1038/nsb766
1838:
1819:(5): 1173–83.
1802:
1758:
1723:
1688:
1653:
1639:
1587:
1569:
1551:
1530:
1508:
1507:
1505:
1502:
1485:
1482:
1469:
1466:
1366:
1365:
1362:
1361:
1356:
1346:
1345:
1339:
1338:
1335:
1334:
1332:
1330:
1323:
1322:
1315:
1308:
1304:
1303:
1300:
1299:
1291:
1290:
1284:
1281:
1280:
1262:
1261:
1255:
1251:
1250:
1247:
1246:
1236:
1235:
1229:
1226:
1225:
1207:
1206:
1200:
1196:
1195:
1192:
1191:
1183:
1182:
1176:
1173:
1172:
1164:
1163:
1157:
1151:
1150:
1147:
1146:
1138:
1137:
1131:
1128:
1127:
1119:
1118:
1112:
1106:
1105:
1102:
1101:
1093:
1092:
1086:
1083:
1082:
1074:
1073:
1067:
1061:
1060:
1055:
1050:
1046:
1045:
1035:
1034:
1031:
1030:
1019:
1018:
1016:
1015:
1010:
1005:
1000:
995:
990:
985:
980:
975:
970:
965:
960:
955:
950:
945:
940:
935:
930:
925:
920:
915:
910:
905:
900:
895:
890:
885:
880:
875:
870:
865:
860:
855:
850:
845:
840:
835:
830:
825:
820:
815:
810:
805:
800:
795:
790:
785:
780:
775:
770:
765:
759:
757:
753:
752:
750:
749:
744:
739:
734:
729:
724:
719:
714:
709:
704:
699:
694:
689:
683:
681:
677:
676:
674:
673:
668:
663:
658:
653:
648:
643:
638:
633:
628:
622:
620:
616:
615:
605:
604:
601:
600:
597:
596:
588:
587:
576:
570:
569:
566:
565:
557:
556:
553:
552:
550:
549:
545:
541:
537:
533:
529:
525:
521:
517:
513:
509:
506:
505:
494:
491:
490:
488:
487:
483:
482:body of uterus
479:
475:
471:
467:
463:
459:
455:
451:
450:saphenous vein
447:
444:
443:
431:
430:
422:
411:
405:
404:
401:RNA expression
393:
392:
389:
388:
380:
376:
375:
367:
364:
359:
353:
352:
343:
336:
330:
326:
325:
320:
314:
313:
305:
304:
292:
291:
288:
287:
279:
275:
274:
266:
263:
258:
252:
251:
242:
235:
229:
225:
224:
217:
211:
210:
202:
201:
189:
188:
145:
141:
140:
132:
124:
123:
119:
118:
115:
114:
111:
110:
80:
79:
71:
70:
59:
53:
52:
44:
43:
35:
34:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
5644:
5633:
5630:
5628:
5625:
5623:
5620:
5619:
5617:
5602:
5599:
5596:
5595:
5591:
5588:
5585:
5582:
5579:
5578:
5575:
5574:Tomoregulin 1
5572:
5570:
5567:
5565:
5562:
5560:
5557:
5555:
5552:
5550:
5549:Gremlin (Drm)
5547:
5545:
5542:
5540:
5537:
5535:
5532:
5530:
5527:
5525:
5522:
5520:
5517:
5514:
5513:
5511:
5507:
5496:
5492:
5488:
5484:
5481:
5478:
5474:
5470:
5467:
5465:
5462:
5459:
5458:
5456:
5454:
5447:
5444:
5442:
5438:
5428:
5425:
5422:
5421:
5419:
5417:
5406:
5400:
5397:
5394:
5393:
5389:
5385:
5381:
5378:
5375:
5371:
5367:
5364:
5361:
5360:
5357:
5354:
5352:
5349:
5347:
5344:
5342:
5339:
5336:
5332:
5328:
5324:
5320:
5316:
5313:
5311:
5308:
5306:
5303:
5300:
5296:
5292:
5288:
5284:
5281:
5278:
5274:
5270:
5266:
5263:
5260:
5259:
5257:
5255:
5249:
5243:
5240:
5237:
5236:
5232:
5228:
5224:
5221:
5218:
5214:
5210:
5207:
5204:
5203:
5200:
5197:
5195:
5192:
5190:
5187:
5184:
5180:
5176:
5172:
5168:
5164:
5160:
5156:
5152:
5149:
5147:
5144:
5142:
5139:
5136:
5132:
5128:
5124:
5120:
5116:
5112:
5108:
5104:
5101:
5098:
5094:
5090:
5086:
5083:
5080:
5079:
5077:
5075:
5064:
5057:
5053:
5049:
5046:
5043:
5042:
5039:
5036:
5033:
5029:
5025:
5021:
5017:
5014:
5012:
5009:
5007:
5004:
5001:
4997:
4993:
4989:
4985:
4981:
4978:
4975:
4974:
4972:
4970:
4964:
4958:
4955:
4953:
4950:
4947:
4946:
4943:
4940:
4938:
4935:
4933:
4930:
4927:
4926:
4922:
4918:
4914:
4910:
4907:
4904:
4900:
4897:
4895:
4892:
4889:
4888:
4886:
4884:
4878:
4875:
4873:
4869:
4859:
4856:
4854:
4851:
4849:
4846:
4843:
4842:
4838:
4834:
4830:
4827:
4824:
4823:
4820:
4817:
4814:
4810:
4806:
4802:
4799:
4796:
4795:
4793:
4791:
4780:
4774:
4771:
4769:
4766:
4764:
4761:
4758:
4757:
4754:
4751:
4748:
4744:
4740:
4736:
4732:
4728:
4725:
4723:
4720:
4718:
4715:
4712:
4708:
4704:
4700:
4696:
4692:
4688:
4684:
4680:
4677:
4674:
4673:
4671:
4669:
4658:
4652:
4649:
4647:
4644:
4642:
4639:
4637:
4634:
4632:
4629:
4627:
4624:
4622:
4619:
4617:
4614:
4612:
4609:
4607:
4604:
4602:
4599:
4597:
4594:
4591:
4590:
4587:
4584:
4582:
4579:
4577:
4574:
4571:
4570:
4566:
4562:
4558:
4554:
4551:
4548:
4544:
4540:
4537:
4535:
4532:
4529:
4528:
4526:
4524:
4513:
4507:
4504:
4502:
4499:
4497:
4494:
4491:
4490:
4486:
4482:
4478:
4475:
4472:
4468:
4464:
4461:
4458:
4457:
4454:
4451:
4449:
4446:
4443:
4439:
4435:
4431:
4428:
4425:
4421:
4417:
4413:
4410:
4407:
4406:
4404:
4402:
4391:
4385:
4382:
4380:
4377:
4375:
4372:
4369:
4368:
4365:
4362:
4360:
4357:
4354:
4350:
4346:
4342:
4338:
4334:
4330:
4326:
4323:
4321:
4318:
4315:
4314:
4312:
4310:
4299:
4293:
4290:
4288:
4285:
4283:
4280:
4278:
4275:
4273:
4270:
4267:
4266:
4262:
4258:
4254:
4250:
4247:
4245:
4242:
4239:
4235:
4231:
4227:
4223:
4219:
4216:
4214:
4211:
4209:
4206:
4203:
4199:
4195:
4191:
4188:
4185:
4184:
4182:
4180:
4169:
4163:
4160:
4157:
4156:
4153:
4150:
4147:
4146:
4143:
4140:
4138:
4135:
4132:
4131:
4128:
4127:Ascrinvacumab
4125:
4122:
4121:
4117:
4113:
4109:
4105:
4102:
4099:
4095:
4092:
4090:
4087:
4084:
4080:
4077:
4075:
4072:
4069:
4065:
4061:
4057:
4054:
4051:
4050:
4048:
4046:
4035:
4032:
4030:
4026:
4022:
4019:
4009:
4004:
4002:
3997:
3995:
3990:
3989:
3986:
3974:
3971:
3969:
3966:
3965:
3963:
3959:
3953:
3950:
3948:
3945:
3943:
3940:
3938:
3935:
3933:
3930:
3929:
3927:
3925:
3921:
3915:
3912:
3910:
3907:
3905:
3902:
3900:
3897:
3896:
3894:
3892:
3888:
3876:
3873:
3871:
3868:
3866:
3863:
3862:
3861:
3858:
3856:
3853:
3851:
3848:
3846:
3843:
3841:
3838:
3837:
3835:
3832:
3831:
3825:
3819:
3816:
3814:
3811:
3810:
3808:
3805:
3804:
3800:
3794:
3791:
3789:
3783:
3775:
3772:
3770:
3767:
3765:
3762:
3761:
3760:
3757:
3756:
3754:
3752:
3748:
3742:
3739:
3737:
3734:
3732:
3729:
3728:
3726:
3724:
3720:
3710:
3707:
3705:
3702:
3700:
3697:
3695:
3692:
3691:
3689:
3686:
3683:
3682:hormone-like:
3678:
3671:
3668:
3665:
3662:
3659:
3656:
3653:
3650:
3649:
3647:
3644:
3639:
3633:
3629:
3625:
3622:
3620:
3616:
3612:
3609:
3607:
3603:
3599:
3596:
3595:
3593:
3590:
3589:
3583:
3577:
3573:
3569:
3566:
3564:
3560:
3556:
3553:
3552:
3550:
3547:
3545:
3539:
3536:
3534:
3530:
3526:
3519:
3514:
3512:
3507:
3505:
3500:
3499:
3496:
3484:
3481:
3480:
3478:
3474:
3468:
3465:
3463:
3460:
3459:
3457:
3455:
3451:
3445:
3442:
3440:
3437:
3435:
3432:
3430:
3427:
3425:
3422:
3420:
3417:
3415:
3412:
3410:
3407:
3405:
3402:
3400:
3397:
3396:
3394:
3392:
3388:
3382:
3379:
3376:
3373:
3371:
3367:
3364:
3361:
3358:
3356:
3353:
3351:
3348:
3346:
3343:
3341:
3337:
3334:
3333:
3331:
3329:
3325:
3321:
3311:
3308:
3307:
3305:
3301:
3295:
3292:
3290:
3287:
3283:
3280:
3278:
3275:
3274:
3273:
3270:
3269:
3267:
3263:
3255:
3252:
3250:
3247:
3246:
3245:
3242:
3240:
3237:
3233:
3230:
3228:
3225:
3223:
3220:
3219:
3218:
3215:
3214:
3212:
3208:
3205:
3202:
3198:
3194:
3189:
3185:
3175:
3172:
3168:
3165:
3163:
3160:
3158:
3155:
3153:
3150:
3148:
3145:
3143:
3140:
3138:
3135:
3133:
3130:
3128:
3125:
3123:
3120:
3118:
3115:
3114:
3113:
3110:
3106:
3103:
3101:
3098:
3096:
3093:
3091:
3088:
3086:
3083:
3081:
3078:
3076:
3073:
3071:
3068:
3066:
3063:
3061:
3058:
3057:
3056:
3053:
3052:
3050:
3048:
3043:
3037:
3034:
3030:
3027:
3025:
3022:
3020:
3017:
3015:
3012:
3011:
3010:
3007:
3003:
3000:
2998:
2995:
2993:
2990:
2989:
2988:
2985:
2984:
2982:
2980:
2976:
2971:
2968:
2966:
2962:
2958:
2954:
2947:
2942:
2940:
2935:
2933:
2928:
2927:
2924:
2910:
2904:
2899:
2895:
2889:
2884:
2880:
2874:
2869:
2865:
2856:
2851:
2849:
2844:
2842:
2837:
2836:
2833:
2826:
2822:
2821:
2816:
2812:
2808:
2806:
2803:
2801:
2798:
2797:
2793:
2786:
2782:
2778:
2774:
2770:
2766:
2762:
2758:
2752:
2748:
2744:
2739:
2734:
2730:
2726:
2722:
2717:
2713:
2709:
2704:
2699:
2696:(2): 584–94.
2695:
2691:
2687:
2682:
2678:
2674:
2669:
2664:
2660:
2656:
2653:(2): 557–68.
2652:
2648:
2644:
2639:
2635:
2631:
2626:
2621:
2618:(2): 509–19.
2617:
2613:
2609:
2604:
2600:
2596:
2592:
2588:
2584:
2580:
2576:
2572:
2566:
2562:
2558:
2554:
2550:
2546:
2542:
2536:
2532:
2528:
2523:
2518:
2514:
2510:
2506:
2502:
2498:
2493:
2489:
2485:
2480:
2475:
2471:
2467:
2464:(4): 557–68.
2463:
2459:
2455:
2450:
2446:
2442:
2437:
2432:
2428:
2424:
2421:(2): 527–34.
2420:
2416:
2412:
2407:
2403:
2399:
2395:
2391:
2387:
2383:
2377:
2373:
2369:
2365:
2361:
2358:(6): 959–62.
2357:
2353:
2347:
2343:
2339:
2334:
2329:
2325:
2321:
2317:
2312:
2308:
2304:
2300:
2296:
2293:(3): 235–41.
2292:
2288:
2283:
2279:
2275:
2271:
2267:
2263:
2259:
2256:(4): 415–21.
2255:
2251:
2245:
2241:
2237:
2234:(4): 323–31.
2233:
2229:
2223:
2219:
2215:
2210:
2205:
2201:
2197:
2193:
2189:
2185:
2180:
2176:
2172:
2167:
2162:
2157:
2152:
2148:
2144:
2140:
2136:
2132:
2127:
2123:
2119:
2114:
2109:
2105:
2101:
2097:
2093:
2089:
2084:
2080:
2076:
2071:
2066:
2062:
2058:
2054:
2050:
2046:
2041:
2040:
2035:
2027:
2022:
2019:
2014:
2010:
2006:
2002:
1998:
1994:
1990:
1986:
1982:
1975:
1972:
1967:
1963:
1958:
1953:
1949:
1945:
1942:(3): 480–90.
1941:
1937:
1933:
1926:
1923:
1918:
1914:
1909:
1904:
1901:(2): 584–94.
1900:
1896:
1892:
1885:
1882:
1877:
1873:
1869:
1865:
1861:
1857:
1853:
1849:
1842:
1839:
1834:
1830:
1826:
1822:
1818:
1814:
1806:
1803:
1798:
1794:
1790:
1786:
1782:
1778:
1775:(4): 415–21.
1774:
1770:
1762:
1759:
1754:
1750:
1746:
1742:
1739:(1): 96–108.
1738:
1734:
1727:
1724:
1719:
1715:
1711:
1707:
1703:
1699:
1692:
1689:
1684:
1680:
1676:
1672:
1669:(5): 461–85.
1668:
1664:
1657:
1654:
1649:
1643:
1640:
1635:
1631:
1626:
1621:
1617:
1613:
1609:
1605:
1601:
1594:
1592:
1588:
1583:
1579:
1573:
1570:
1565:
1561:
1555:
1552:
1548:
1544:
1539:
1537:
1535:
1531:
1527:
1523:
1518:
1516:
1514:
1510:
1503:
1501:
1499:
1495:
1491:
1483:
1481:
1479:
1475:
1467:
1465:
1463:
1459:
1455:
1451:
1447:
1443:
1439:
1435:
1430:
1428:
1424:
1420:
1416:
1412:
1408:
1404:
1400:
1399:embryogenesis
1396:
1392:
1387:
1385:
1382:
1381:
1376:
1372:
1360:
1355:
1351:
1347:
1344:
1340:
1333:
1331:
1328:
1324:
1320:
1316:
1313:
1309:
1305:
1298:
1292:
1288:
1285:
1279:
1277:
1273:
1269:
1263:
1259:
1256:
1252:
1245:
1243:
1237:
1233:
1230:
1224:
1222:
1218:
1214:
1208:
1204:
1201:
1199:RefSeq (mRNA)
1197:
1190:
1189:
1184:
1180:
1177:
1171:
1170:
1165:
1161:
1158:
1156:
1152:
1145:
1144:
1139:
1135:
1132:
1126:
1125:
1120:
1116:
1113:
1111:
1107:
1100:
1099:
1094:
1090:
1087:
1081:
1080:
1075:
1071:
1068:
1066:
1062:
1059:
1056:
1054:
1051:
1047:
1044:
1040:
1036:
1029:
1025:
1020:
1014:
1011:
1009:
1006:
1004:
1001:
999:
996:
994:
991:
989:
986:
984:
981:
979:
976:
974:
971:
969:
966:
964:
961:
959:
956:
954:
951:
949:
946:
944:
941:
939:
936:
934:
931:
929:
926:
924:
921:
919:
916:
914:
911:
909:
906:
904:
901:
899:
896:
894:
891:
889:
886:
884:
881:
879:
876:
874:
871:
869:
866:
864:
861:
859:
856:
854:
853:odontogenesis
851:
849:
846:
844:
841:
839:
838:wound healing
836:
834:
831:
829:
826:
824:
821:
819:
816:
814:
811:
809:
806:
804:
801:
799:
796:
794:
791:
789:
786:
784:
781:
779:
776:
774:
771:
769:
766:
764:
761:
760:
758:
755:
754:
748:
745:
743:
740:
738:
735:
733:
730:
728:
725:
723:
720:
718:
715:
713:
710:
708:
705:
703:
700:
698:
695:
693:
690:
688:
685:
684:
682:
679:
678:
672:
669:
667:
664:
662:
659:
657:
654:
652:
649:
647:
644:
642:
639:
637:
634:
632:
629:
627:
624:
623:
621:
618:
617:
614:
613:Gene ontology
610:
606:
594:
589:
585:
580:
577:
575:
571:
563:
558:
547:
543:
539:
535:
531:
527:
523:
519:
515:
511:
510:
507:
503:
498:
495:
485:
481:
477:
473:
469:
465:
461:
457:
453:
449:
448:
445:
441:
436:
433:
432:
429:
427:
423:
421:
420:
416:
415:
412:
410:
406:
402:
398:
394:
386:
381:
377:
373:
368:
358:
354:
347:
340:
334:
327:
319:
315:
311:
306:
302:
297:
293:
285:
280:
276:
272:
267:
257:
253:
246:
239:
233:
226:
222:
216:
212:
208:
203:
199:
194:
190:
186:
182:
178:
174:
170:
166:
162:
158:
154:
150:
142:
137:
130:
125:
120:
109:
107:
103:
99:
95:
91:
87:
81:
76:
73:
72:
68:
65:
58:
54:
49:
45:
41:
36:
31:
19:
5597:
5580:
5515:
5460:
5423:
5395:
5363:Antagonists:
5362:
5261:
5238:
5206:Antagonists:
5205:
5081:
5045:Antagonists:
5044:
4976:
4948:
4937:Lerdelimumab
4932:Fresolimumab
4928:
4890:
4844:
4826:Antagonists:
4825:
4797:
4759:
4675:
4592:
4581:Lerdelimumab
4576:Fresolimumab
4572:
4530:
4492:
4460:Antagonists:
4459:
4408:
4370:
4316:
4268:
4186:
4158:
4152:Dalantercept
4148:
4133:
4123:
4052:
3828:
3797:
3786:Insulin/IGF/
3751:TGFβ pathway
3681:
3642:
3586:
3544:FGF receptor
3542:
2908:
2893:
2878:
2818:
2763:(1): 153–9.
2760:
2756:
2728:
2724:
2693:
2689:
2650:
2646:
2615:
2611:
2577:(2): 103–9.
2574:
2571:The Prostate
2570:
2547:(4): 320–5.
2544:
2540:
2504:
2500:
2461:
2457:
2418:
2414:
2385:
2381:
2355:
2351:
2323:
2319:
2290:
2286:
2253:
2249:
2231:
2227:
2191:
2187:
2138:
2134:
2095:
2091:
2052:
2048:
2021:
1988:
1984:
1974:
1939:
1935:
1925:
1898:
1894:
1884:
1854:(3): 203–8.
1851:
1847:
1841:
1816:
1812:
1805:
1772:
1768:
1761:
1736:
1732:
1726:
1701:
1697:
1691:
1666:
1662:
1656:
1642:
1607:
1603:
1581:
1572:
1563:
1554:
1497:
1493:
1487:
1471:
1468:Interactions
1446:cleft palate
1431:
1411:TGF-β family
1388:
1378:
1370:
1369:
1294:
1272:NP_001316868
1268:NP_001316867
1265:
1239:
1221:NM_001329939
1217:NM_001329938
1210:
1186:
1167:
1141:
1122:
1096:
1077:
1057:
1052:
818:human ageing
712:cell surface
520:aortic valve
424:
417:
144:External IDs
83:
5632:TGFβ domain
5581:Antibodies:
5544:Follistatin
5399:Ramatercept
5242:Sotatercept
4942:Metelimumab
4929:Antibodies:
4586:Metelimumab
4573:Antibodies:
4162:Disitertide
4124:Antibodies:
3454:Coreceptors
3414:Follistatin
3324:Transducers
2861:PDB gallery
1698:Development
1403:development
544:ankle joint
458:gallbladder
383:86,125,815
370:86,103,519
282:75,983,011
269:75,958,097
122:Identifiers
5616:Categories
5584:Stamulumab
5534:DAN (PARN)
5453:(β-glycan)
5356:Radotermin
5199:Radotermin
5179:11 (BMP11)
5135:15 (GDF9B)
5038:Radotermin
4903:10 (BMP3B)
4813:11 (BMP11)
4753:Radotermin
4711:15 (GDF9B)
4616:LY-2109761
4547:11 (BMP11)
4543:10 (BMP3B)
4442:11 (BMP11)
4021:modulators
3973:Hepatocyte
3533:Fibroblast
3310:betaglycan
3045:Ligand of
2973:Ligand of
1549:, May 2017
1528:, May 2017
1504:References
540:belly cord
486:C1 segment
428:(ortholog)
165:HomoloGene
18:TGF beta 3
5464:Avotermin
5427:AMH (MIS)
5424:Agonists:
5335:7 (BMP12)
5331:6 (BMP13)
5327:5 (BMP14)
5262:Agonists:
5171:7 (BMP12)
5167:6 (BMP13)
5163:5 (BMP14)
5082:Agonists:
5032:7 (BMP12)
5028:6 (BMP13)
5024:5 (BMP14)
4977:Agonists:
4957:LY-364947
4894:Avotermin
4891:Agonists:
4858:SB-505124
4853:SB-431542
4798:Agonists:
4739:7 (BMP12)
4735:6 (BMP13)
4731:5 (BMP14)
4676:Agonists:
4646:SB-525334
4641:SB-505124
4636:SB-431542
4611:LY-364947
4606:GW-788388
4534:Avotermin
4531:Agonists:
4506:SB-505124
4501:SB-431542
4409:Agonists:
4320:AMH (MIS)
4317:Agonists:
4213:Avotermin
4208:AMH (MIS)
4187:Agonists:
4074:Avotermin
4053:Agonists:
1494:avotermin
1458:epidermal
1276:NP_003230
1242:NM_009368
1213:NM_003239
1043:Orthologs
687:cytoplasm
173:GeneCards
5627:Proteins
5601:Endoglin
5509:Unsorted
5461:Ligands:
5441:Type III
5020:2 (BMP9)
4626:R-268712
4098:2 (BMP9)
4089:Cetermin
3685:FGF15/19
3546:ligands:
3399:Cerberus
2785:21284888
2777:10457363
2747:10187774
2599:22734222
2278:22365206
2079:14679171
2013:35671002
2005:19362676
1966:11157754
1876:13322593
1868:11850637
1833:12729750
1797:22365206
1753:14729481
1718:10433915
1683:15062644
1634:16549496
1545:–
1524:–
1474:interact
1427:activins
1423:inhibins
1421:(GDFs),
1417:(BMPs),
1391:cytokine
1343:Wikidata
1022:Sources:
697:T-tubule
548:calvaria
462:prostate
5598:Others:
5539:Decorin
5529:Chordin
5469:Inhibin
5366:Inhibin
5265:Activin
5209:Inhibin
5085:Activin
5048:Inhibin
4872:Type II
4848:A 83-01
4773:K-02288
4596:A 83-01
4496:A 83-01
4463:Inhibin
4412:Activin
4384:K-02288
4287:K-02288
4190:Activin
4137:K-02288
4056:Activin
3860:Relaxin
3799:Insulin
3419:Gremlin
3409:Decorin
3404:Chordin
3303:TGFBR3:
3265:TGFBR2:
3210:TGFBR1:
3193:Activin
2825:PDBe-KB
2815:UniProt
2712:9872992
2677:9683588
2668:1377298
2634:9250163
2625:1858020
2591:9140123
2561:8886879
2531:8819159
2522:2143453
2488:8106553
2479:2119924
2445:8093006
2436:1137259
2402:7962292
2372:7951245
2342:7852346
2307:7796607
2270:7493022
2240:3226728
2218:3208746
2175:3164476
2143:Bibcode
2122:1875922
1917:9872992
1789:7493022
1625:2063766
1547:Ensembl
1526:Ensembl
1498:Juvista
1375:protein
1155:UniProt
1110:Ensembl
1049:Species
1028:QuickGO
727:nucleus
403:pattern
261:14q24.3
129:Aliases
5590:TRC105
5559:Noggin
5451:TGFβR3
5253:ACVR2B
5068:ACVR2A
4882:TGFβR2
4788:ACVR1C
4666:BMPR1B
4651:SD-208
4601:D-4476
4521:TGFβR1
4399:ACVR1B
4307:BMPR1A
4177:ACVR1A
4043:ACVRL1
4029:Type I
3947:VEGF-D
3942:VEGF-C
3937:VEGF-B
3932:VEGF-A
3741:HB-EGF
3672:(FHF4)
3666:(FHF2)
3660:(FHF1)
3654:(FHF3)
3467:Cripto
3434:Noggin
3366:I-SMAD
3336:R-SMAD
3282:ACVR2B
3277:ACVR2A
3254:BMPR1B
3249:BMPR1A
3239:ACVRL1
3232:ACVR1C
3227:ACVR1B
3201:family
3002:TGF-β3
2997:TGF-β2
2992:TGF-β1
2820:P10600
2783:
2775:
2745:
2710:
2675:
2665:
2632:
2622:
2597:
2589:
2559:
2529:
2519:
2486:
2476:
2443:
2433:
2400:
2370:
2340:
2305:
2276:
2268:
2238:
2216:
2209:454948
2206:
2173:
2166:280506
2163:
2120:
2113:361291
2110:
2077:
2070:297008
2067:
2011:
2003:
1985:Lancet
1964:
1957:133482
1954:
1915:
1874:
1866:
1831:
1795:
1787:
1751:
1716:
1681:
1632:
1622:
1490:trials
1462:dermal
1442:palate
1329:search
1327:PubMed
1188:P17125
1169:P10600
1065:Entrez
574:BioGPS
153:190230
5554:LTBP1
5519:BAMBI
5410:AMHR2
5380:Lefty
5346:Nodal
5223:Lefty
5194:Nodal
5072:ACVR2
4968:BMPR2
4952:DMH-2
4829:Lefty
4819:Nodal
4763:DMH-2
4477:Lefty
4453:Nodal
4374:DMH-2
4277:DMH-2
4272:DMH-1
3968:Nerve
3961:Other
3914:PDGFD
3909:PDGFC
3904:PDGFB
3899:PDGFA
3855:INSL6
3850:INSL5
3845:INSL4
3840:INSL3
3774:TGFβ3
3769:TGFβ2
3764:TGFβ1
3709:FGF23
3704:FGF21
3699:FGF19
3694:FGF15
3670:FGF14
3664:FGF13
3658:FGF12
3652:FGF11
3632:FGF20
3628:FGF16
3619:FGF18
3615:FGF17
3606:FGF22
3602:FGF10
3476:Other
3462:BAMBI
3444:THBS1
3429:LTBP1
3424:Lefty
3381:SMAD4
3375:SMAD7
3370:SMAD6
3360:SMAD9
3355:SMAD5
3350:SMAD3
3345:SMAD2
3340:SMAD1
3294:BMPR2
3289:AMHR2
3244:BMPR1
3222:ACVR1
3167:GDF15
3162:GDF11
3157:GDF10
3105:BMP15
3100:BMP10
3095:BMP8b
3090:BMP8a
3036:Nodal
3029:INHBC
3024:INHBB
3019:INHBA
2979:TGFBR
2781:S2CID
2595:S2CID
2274:S2CID
2009:S2CID
1872:S2CID
1793:S2CID
1476:with
1454:lungs
1380:TGFB3
1373:is a
1098:21809
1058:Mouse
1053:Human
1024:Amigo
536:ankle
516:molar
426:Mouse
419:Human
366:Start
301:Mouse
265:Start
198:Human
177:TGFB3
161:98727
136:TGFB3
33:TGFB3
5564:TGIF
5483:TGFβ
5414:AMHR
4909:TGFβ
4784:ALK7
4662:ALK6
4553:TGFβ
4517:ALK5
4395:ALK4
4303:ALK3
4249:TGFβ
4173:ALK2
4104:TGFβ
4039:ALK1
4016:TGFβ
3818:IGF2
3813:IGF1
3801:and
3759:TGFβ
3731:TGFα
3624:FGF9
3611:FGF8
3598:FGF7
3576:FGF6
3572:FGF4
3568:FGF3
3563:FGF5
3559:FGF2
3555:FGF1
3483:SARA
3439:PARN
3328:SMAD
3152:GDF9
3142:GDF7
3137:GDF6
3132:GDF5
3127:GDF3
3122:GDF2
3117:GDF1
3085:BMP7
3080:BMP6
3075:BMP5
3070:BMP4
3065:BMP3
3060:BMP2
3047:BMPR
3014:INHA
2975:ACVR
2909:1tgk
2894:1tgj
2879:1ktz
2813:for
2773:PMID
2743:PMID
2708:PMID
2673:PMID
2630:PMID
2587:PMID
2557:PMID
2527:PMID
2484:PMID
2441:PMID
2398:PMID
2368:PMID
2338:PMID
2303:PMID
2266:PMID
2236:PMID
2214:PMID
2171:PMID
2118:PMID
2075:PMID
2001:PMID
1962:PMID
1913:PMID
1864:PMID
1829:PMID
1785:PMID
1749:PMID
1714:PMID
1679:PMID
1630:PMID
1460:and
1436:and
1425:and
1401:and
1384:gene
1079:7043
409:Bgee
357:Band
318:Chr.
256:Band
215:Chr.
169:2433
149:OMIM
106:4UM9
102:3EO1
98:2PJY
94:1TGK
90:1TGJ
86:1KTZ
67:RCSB
64:PDBe
5315:GDF
5283:BMP
5151:GDF
5103:BMP
5016:GDF
4980:BMP
4899:GDF
4801:GDF
4727:GDF
4679:BMP
4539:GDF
4430:GDF
4325:BMP
4218:BMP
4094:GDF
4079:BMP
3952:PGF
3736:EGF
3588:KGF
3197:BMP
2977:or
2811:PDB
2765:doi
2761:181
2733:doi
2729:274
2698:doi
2694:274
2663:PMC
2655:doi
2620:PMC
2616:151
2579:doi
2549:doi
2517:PMC
2509:doi
2474:PMC
2466:doi
2462:124
2431:PMC
2423:doi
2419:302
2390:doi
2360:doi
2328:doi
2324:270
2295:doi
2258:doi
2204:PMC
2196:doi
2161:PMC
2151:doi
2108:PMC
2100:doi
2065:PMC
2057:doi
2053:112
1993:doi
1989:373
1952:PMC
1944:doi
1903:doi
1899:274
1856:doi
1821:doi
1817:328
1777:doi
1741:doi
1737:266
1706:doi
1702:126
1671:doi
1620:PMC
1612:doi
1608:172
1296:n/a
379:End
278:End
181:OMA
157:MGI
57:PDB
5618::
5493:,
5489:,
5475:,
5386:,
5372:,
5333:,
5329:,
5325:,
5321:,
5297:,
5293:,
5289:,
5277:AB
5275:,
5271:,
5229:,
5215:,
5183:15
5181:,
5177:,
5173:,
5169:,
5165:,
5161:,
5157:,
5133:,
5131:8B
5129:,
5127:8A
5125:,
5121:,
5117:,
5113:,
5109:,
5097:AB
5095:,
5091:,
5054:,
5030:,
5026:,
5022:,
5000:10
4998:,
4994:,
4990:,
4986:,
4919:,
4915:,
4835:,
4811:,
4807:,
4747:15
4745:,
4741:,
4737:,
4733:,
4709:,
4707:8B
4705:,
4703:8A
4701:,
4697:,
4693:,
4689:,
4685:,
4563:,
4559:,
4545:,
4483:,
4469:,
4440:,
4436:,
4424:AB
4422:,
4418:,
4353:8B
4351:,
4349:8A
4347:,
4343:,
4339:,
4335:,
4331:,
4259:,
4255:,
4238:8B
4236:,
4234:8A
4232:,
4228:,
4224:,
4202:AB
4200:,
4196:,
4114:,
4110:,
4083:10
4068:AB
4066:,
4062:,
3199:,
3195:,
2955::
2817::
2779:.
2771:.
2759:.
2741:.
2727:.
2723:.
2706:.
2692:.
2688:.
2671:.
2661:.
2651:63
2649:.
2645:.
2628:.
2614:.
2610:.
2593:.
2585:.
2575:31
2573:.
2555:.
2545:15
2543:.
2525:.
2515:.
2503:.
2499:.
2482:.
2472:.
2460:.
2456:.
2439:.
2429:.
2417:.
2413:.
2396:.
2386:79
2384:.
2366:.
2354:.
2336:.
2322:.
2318:.
2301:.
2291:14
2289:.
2272:.
2264:.
2254:11
2252:.
2230:.
2212:.
2202:.
2190:.
2186:.
2169:.
2159:.
2149:.
2139:85
2137:.
2133:.
2116:.
2106:.
2096:11
2094:.
2090:.
2073:.
2063:.
2051:.
2047:.
2007:.
1999:.
1987:.
1983:.
1960:.
1950:.
1940:20
1938:.
1934:.
1911:.
1897:.
1893:.
1870:.
1862:.
1850:.
1827:.
1815:.
1791:.
1783:.
1773:11
1771:.
1747:.
1735:.
1712:.
1700:.
1677:.
1667:28
1665:.
1628:.
1618:.
1606:.
1602:.
1590:^
1580:.
1562:.
1533:^
1512:^
1480:.
1429:.
1413:,
1397:,
1386:.
1026:/
385:bp
372:bp
284:bp
271:bp
179:;
175::
171:;
167::
163:;
159::
155:;
151::
104:,
100:,
96:,
92:,
88:,
5497:)
5495:3
5491:2
5487:1
5485:(
5479:)
5477:B
5473:A
5471:(
5416:)
5412:(
5390:)
5388:2
5384:1
5382:(
5376:)
5374:B
5370:A
5368:(
5337:)
5323:3
5319:1
5317:(
5301:)
5299:7
5295:6
5291:4
5287:2
5285:(
5279:)
5273:B
5269:A
5267:(
5233:)
5231:2
5227:1
5225:(
5219:)
5217:B
5213:A
5211:(
5185:)
5175:9
5159:3
5155:1
5153:(
5137:)
5123:7
5119:6
5115:5
5111:4
5107:2
5105:(
5099:)
5093:B
5089:A
5087:(
5074:)
5070:(
5058:)
5056:B
5052:A
5050:(
5034:)
5018:(
5002:)
4996:7
4992:6
4988:4
4984:2
4982:(
4923:)
4921:3
4917:2
4913:1
4911:(
4905:)
4901:(
4839:)
4837:2
4833:1
4831:(
4815:)
4809:3
4805:1
4803:(
4790:)
4786:(
4749:)
4743:9
4729:(
4713:)
4699:7
4695:6
4691:5
4687:4
4683:2
4681:(
4668:)
4664:(
4567:)
4565:3
4561:2
4557:1
4555:(
4549:)
4541:(
4523:)
4519:(
4487:)
4485:2
4481:1
4479:(
4473:)
4471:B
4467:A
4465:(
4444:)
4438:3
4434:1
4432:(
4426:)
4420:B
4416:A
4414:(
4401:)
4397:(
4355:)
4345:7
4341:6
4337:5
4333:4
4329:2
4327:(
4309:)
4305:(
4263:)
4261:3
4257:2
4253:1
4251:(
4240:)
4230:7
4226:6
4222:5
4220:(
4204:)
4198:B
4194:A
4192:(
4179:)
4175:(
4118:)
4116:3
4112:2
4108:1
4106:(
4100:)
4096:(
4085:)
4081:(
4070:)
4064:B
4060:A
4058:(
4045:)
4041:(
4007:e
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