Knowledge (XXG)

Homeobox protein TGIF1

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responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of
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Dubourg C, Lazaro L, Pasquier L, Bendavid C, Blayau M, Le Duff F, Durou MR, Odent S, David V (2004). "Molecular screening of SHH, ZIC2, SIX3, and TGIF genes in patients with features of holoprosencephaly spectrum: Mutation review and genotype-phenotype correlations".
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Aguilella C, Dubourg C, Attia-Sobol J, Vigneron J, Blayau M, Pasquier L, Lazaro L, Odent S, David V (2003). "Molecular screening of the TGIF gene in holoprosencephaly: identification of two novel mutations".
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Chen CP, Chern SR, Du SH, Wang W (2002). "Molecular diagnosis of a novel heterozygous 268C-->T (R90C) mutation in TGIF gene in a fetus with holoprosencephaly and premaxillary agenesis".
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MĂĽnke M, Page DC, Brown LG, Armson BA, Zackai EH, Mennuti MT, Emanuel BS (1989). "Molecular detection of a Yp/18 translocation in a 45,X holoprosencephalic male".
1400:, Massagué J, Muenke M, Elledge SJ (June 2000). "Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination". 784: 765: 145: 1256: 1207: 2393: 2369: 1856:"The interaction of the carboxyl terminus-binding protein with the Smad corepressor TGIF is disrupted by a holoprosencephaly mutation in TGIF" 1527:"The interaction of the carboxyl terminus-binding protein with the Smad corepressor TGIF is disrupted by a holoprosencephaly mutation in TGIF" 2388: 1337: 1319: 1222:
type 4, which is a structural anomaly of the brain. It has also been associated with risk of otitis media (inflammation of the middle ear)
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El-Jaick KB, Powers SE, Bartholin L, Myers KR, Hahn J, Orioli IM, Ouspenskaia M, Lacbawan F, Roessler E, Wotton D, Muenke M (2007).
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Wotton D, Knoepfler PS, Laherty CD, Eisenman RN, Massagué J (2001). "The Smad transcriptional corepressor TGIF recruits mSin3".
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Lam DS, Lee WS, Leung YF, Tam PO, Fan DS, Fan BJ, Pang CP (2003). "TGFbeta-induced factor: a candidate gene for high myopia".
208: 183: 1302: 1185:. Alternative splicing has been observed at this locus and eight variants, encoding four distinct isoforms, are described. 1281: 1201:
proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized
125: 1231: 322: 221: 2362: 1357:"A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif" 1193:
The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical
315: 214: 829: 133: 1934:"c-Jun interacts with the corepressor TG-interacting factor (TGIF) to suppress Smad2 transcriptional activity" 1465:"c-Jun interacts with the corepressor TG-interacting factor (TGIF) to suppress Smad2 transcriptional activity" 810: 1821:"Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription" 2355: 197: 1945: 1476: 112: 2086:"HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences" 1202: 1091: 1087: 1083: 1079: 1058: 1054: 1012: 1008: 1004: 980: 976: 972: 968: 947: 943: 901: 897: 893: 2302: 2192: 2154: 1807: 1729: 1638: 1463:
Pessah M, Prunier C, Marais J, Ferrand N, Mazars A, Lallemand F, Gauthier JM, Atfi A (May 2001).
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and may participate in the transmission of nuclear signals during development and in the adult.
1095: 1050: 1046: 1042: 1038: 1034: 1030: 1020: 1016: 984: 939: 935: 931: 927: 923: 919: 909: 905: 1891:"Epidermal growth factor signaling via Ras controls the Smad transcriptional co-repressor TGIF" 2294: 2264: 2235: 2184: 2146: 2117: 2072: 2037: 2016: 1973: 1920: 1877: 1842: 1799: 1764: 1721: 1692: 1630: 1589: 1548: 1504: 1417: 1378: 1219: 560: 105: 53: 2339: 1932:
Pessah M, Prunier C, Marais J, Ferrand N, Mazars A, Lallemand F, Gauthier JM, Atfi A (2001).
2286: 2256: 2225: 2217: 2176: 2138: 2107: 2097: 2062: 2006: 1998: 1987:"Inhibition of androgen receptor-mediated transcription by amino-terminal enhancer of split" 1963: 1953: 1910: 1902: 1867: 1832: 1789: 1754: 1713: 1682: 1674: 1620: 1579: 1538: 1494: 1484: 1409: 1368: 1194: 402: 333: 277: 232: 153: 377: 2051:"5'TG3' interacting factor interacts with Sin3A and represses AR-mediated transcription" 1949: 1480: 2230: 2205: 1759: 1742: 1687: 1662: 1915: 1890: 1794: 1777: 1625: 1608: 699: 694: 689: 684: 679: 674: 658: 653: 637: 632: 627: 622: 617: 612: 607: 602: 2382: 2335: 2011: 2002: 1986: 1968: 1933: 1499: 1464: 1397: 589: 2306: 1733: 1429: 137: 2196: 2158: 1811: 1642: 395: 174: 1396:
Gripp KW, Wotton D, Edwards MC, Roessler E, Ades L, Meinecke P, Richieri-Costa A,
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National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
478: 2180: 294: 191: 141: 1906: 1373: 1356: 2067: 2050: 1663:"Functional analysis of mutations in TGIF associated with holoprosencephaly" 729: 538: 416: 361: 348: 260: 247: 149: 2298: 2268: 2239: 2188: 2150: 2121: 2102: 2085: 2076: 2041: 2020: 1977: 1958: 1924: 1881: 1872: 1855: 1846: 1837: 1820: 1803: 1696: 1634: 1593: 1584: 1567: 1552: 1543: 1526: 1508: 1489: 1421: 1768: 1725: 1382: 1159: 1154: 2260: 1741:
Overhauser J, Mitchell HF, Zackai EH, Tick DB, Rojas K, Muenke M (1995).
1198: 1143: 874: 855: 2206:"Regulation of TG-interacting factor by transforming growth factor-beta" 2112: 1568:"TGIF2 interacts with histone deacetylase 1 and represses transcription" 623:
DNA-binding transcription repressor activity, RNA polymerase II-specific
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DNA-binding transcription factor activity, RNA polymerase II-specific
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RNA polymerase II cis-regulatory region sequence-specific DNA binding
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Yang Y, Hwang CK, D'Souza UM, Lee SH, Junn E, Mouradian MM (2000).
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Bertolino E, Reimund B, Wildt-Perinic D, Clerc RG (February 1996).
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Chen F, Ogawa K, Nagarajan RP, Zhang M, Kuang C, Chen Y (2003).
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negative regulation of transcription by RNA polymerase II
385: 2343: 550: 1447:"Entrez Gene: TGIF1 TGFB-induced factor homeobox 1" 1072: 1003: 961: 892: 1298: 1296: 1294: 1277: 1275: 1273: 1607:Wotton D, Lo RS, Lee S, MassaguĂ© J (April 1999). 332: 231: 1566:Melhuish TA, Gallo CM, Wotton D (August 2001). 1520: 1518: 1458: 1456: 1303:GRCm38: Ensembl release 89: ENSMUSG00000047407 2363: 8: 116:, HPE4, TGIF, TGFB induced factor homeobox 1 1776:Wotton D, Lo RS, Lee S, MassaguĂ© J (1999). 1282:GRCh38: Ensembl release 89: ENSG00000177426 1218:Mutations in this gene are associated with 690:cellular response to growth factor stimulus 2370: 2356: 1000: 889: 725: 675:regulation of transcription, DNA-templated 585: 373: 272: 169: 71: 2229: 2111: 2101: 2066: 2010: 1967: 1957: 1914: 1871: 1836: 1793: 1758: 1686: 1624: 1583: 1542: 1498: 1488: 1372: 1257:Mothers against decapentaplegic homolog 2 1230:Homeobox protein TGIF1 has been shown to 613:DNA-binding transcription factor activity 1441: 1439: 1525:Melhuish TA, Wotton D (December 2000). 1269: 1985:Yu X, Li P, Roeder RG, Wang Z (2001). 680:negative regulation of gene expression 31: 337: 298: 293: 236: 195: 190: 7: 2320: 2318: 1889:Lo RS, Wotton D, MassaguĂ© J (2001). 1778:"A Smad transcriptional corepressor" 1609:"A Smad transcriptional corepressor" 1178:that, in humans, is encoded by the 2342:. You can help Knowledge (XXG) by 1069: 958: 865: 846: 820: 801: 775: 756: 685:multicellular organism development 628:transcription corepressor activity 555: 473: 411: 390: 25: 2322: 2003:10.1128/MCB.21.14.4614-4625.2001 559: 321: 314: 308: 285: 220: 213: 207: 182: 2084:Dintilhac A, BernuĂ©s J (2002). 2394:Human chromosome 18 gene stubs 1854:Melhuish TA, Wotton D (2001). 570:More reference expression data 539:More reference expression data 1: 1795:10.1016/S0092-8674(00)80712-6 1626:10.1016/s0092-8674(00)80712-6 306: 205: 2389:Genes on human chromosome 18 2249:Invest. Ophthalmol. Vis. Sci 1938:Proc. Natl. Acad. Sci. U.S.A 1469:Proc. Natl. Acad. Sci. U.S.A 700:transcription, DNA-templated 1679:10.1016/j.ymgme.2006.07.011 427:stromal cell of endometrium 2410: 2317: 2181:10.1007/s00439-002-0862-8 1338:"Mouse PubMed Reference:" 1320:"Human PubMed Reference:" 1158: 1153: 1149: 1142: 1126: 1107: 1076: 1027: 996: 965: 916: 885: 872: 868: 853: 849: 840: 827: 823: 808: 804: 795: 782: 778: 763: 759: 750: 735: 728: 724: 708: 588: 584: 567: 558: 549: 536: 485: 476: 423: 414: 384: 376: 372: 355: 342: 305: 284: 275: 271: 254: 241: 204: 181: 172: 168: 123: 120: 110: 103: 98: 79: 74: 57: 52: 47: 43: 39: 34: 2049:Sharma M, Sun Z (2002). 1374:10.1074/jbc.270.52.31178 1120:Chr 17: 71.15 – 71.16 Mb 2068:10.1210/mend.15.11.0732 29:Protein found in humans 2103:10.1074/jbc.M108417200 1959:10.1073/pnas.101579798 1907:10.1093/emboj/20.1.128 1873:10.1074/jbc.C000416200 1838:10.1074/jbc.M908382199 1585:10.1074/jbc.M103377200 1544:10.1074/jbc.C000416200 1490:10.1073/pnas.101579798 1172:Homeobox protein TGIF1 1113:Chr 18: 3.41 – 3.46 Mb 1214:Clinical significance 300:Chromosome 17 (mouse) 198:Chromosome 18 (human) 2261:10.1167/iovs.02-0058 75:List of PDB id codes 48:Available structures 1950:2001PNAS...98.6198P 1481:2001PNAS...98.6198P 1203:retinoid X receptor 2330:This article on a 2291:10.1002/humu.20056 2222:10.1042/BJ20030095 2030:Cell Growth Differ 1718:10.1007/BF01790089 830:ENSMUSG00000047407 668:Biological process 647:Cellular component 596:Molecular function 451:right uterine tube 2351: 2350: 1747:Am. J. Hum. Genet 1667:Mol. Genet. Metab 1220:holoprosencephaly 1169: 1168: 1165: 1164: 1138: 1137: 1103: 1102: 1066: 1065: 992: 991: 955: 954: 881: 880: 862: 861: 836: 835: 817: 816: 791: 790: 772: 771: 720: 719: 580: 579: 576: 575: 545: 544: 532: 531: 470: 469: 455:left uterine tube 439:corpus epididymis 368: 367: 267: 266: 162:TGIF1 - orthologs 94: 93: 90: 89: 58:Ortholog search: 16:(Redirected from 2401: 2372: 2365: 2358: 2326: 2319: 2310: 2272: 2243: 2233: 2216:(Pt 2): 257–63. 2200: 2162: 2125: 2115: 2105: 2080: 2070: 2045: 2024: 2014: 1981: 1971: 1961: 1944:(11): 6198–203. 1928: 1918: 1885: 1875: 1850: 1840: 1831:(27): 20734–41. 1815: 1797: 1772: 1762: 1737: 1700: 1690: 1647: 1646: 1628: 1604: 1598: 1597: 1587: 1578:(34): 32109–14. 1563: 1557: 1556: 1546: 1522: 1513: 1512: 1502: 1492: 1475:(11): 6198–203. 1460: 1451: 1450: 1443: 1434: 1433: 1393: 1387: 1386: 1376: 1367:(52): 31178–88. 1352: 1346: 1345: 1334: 1328: 1327: 1316: 1310: 1300: 1289: 1279: 1151: 1150: 1122: 1115: 1098: 1070: 1061: 1001: 997:RefSeq (protein) 987: 959: 950: 890: 866: 847: 821: 802: 776: 757: 726: 586: 572: 563: 556: 541: 525:primitive streak 493:genital tubercle 481: 479:Top expressed in 474: 459:cartilage tissue 435:ventricular zone 419: 417:Top expressed in 412: 391: 374: 364: 351: 340: 325: 318: 312: 301: 289: 273: 263: 250: 239: 224: 217: 211: 200: 186: 170: 164: 115: 108: 85: 72: 66: 45: 44: 32: 21: 2409: 2408: 2404: 2403: 2402: 2400: 2399: 2398: 2379: 2378: 2377: 2376: 2315: 2313: 2275: 2246: 2203: 2165: 2128: 2083: 2061:(11): 1918–28. 2055:Mol. Endocrinol 2048: 2027: 1997:(14): 4614–25. 1991:Mol. Cell. Biol 1984: 1931: 1901:(1–2): 128–36. 1888: 1866:(50): 39762–6. 1853: 1818: 1775: 1740: 1703: 1660: 1656: 1654:Further reading 1651: 1650: 1606: 1605: 1601: 1565: 1564: 1560: 1537:(50): 39762–6. 1524: 1523: 1516: 1462: 1461: 1454: 1445: 1444: 1437: 1395: 1394: 1390: 1354: 1353: 1349: 1336: 1335: 1331: 1318: 1317: 1313: 1301: 1292: 1280: 1271: 1266: 1228: 1216: 1191: 1160:View/Edit Mouse 1155:View/Edit Human 1118: 1111: 1108:Location (UCSC) 1094: 1090: 1086: 1082: 1078: 1057: 1053: 1049: 1045: 1041: 1037: 1033: 1029: 1023: 1019: 1015: 1011: 1007: 983: 979: 975: 971: 967: 946: 942: 938: 934: 930: 926: 922: 918: 912: 908: 904: 900: 896: 811:ENSG00000177426 704: 663: 642: 638:co-SMAD binding 608:protein binding 568: 537: 528: 523: 519: 515: 511: 507: 503: 499: 495: 491: 477: 466: 463:skin of abdomen 461: 457: 453: 449: 445: 441: 437: 433: 429: 415: 359: 346: 339:17|17 E1.3 338: 328: 327: 326: 319: 299: 276:Gene location ( 258: 245: 237: 227: 226: 225: 218: 196: 173:Gene location ( 124: 111: 104: 81: 59: 30: 23: 22: 15: 12: 11: 5: 2407: 2405: 2397: 2396: 2391: 2381: 2380: 2375: 2374: 2367: 2360: 2352: 2349: 2348: 2327: 2312: 2311: 2273: 2244: 2201: 2163: 2143:10.1002/pd.202 2126: 2081: 2046: 2025: 1982: 1929: 1886: 1851: 1816: 1773: 1738: 1701: 1657: 1655: 1652: 1649: 1648: 1599: 1558: 1514: 1452: 1435: 1388: 1347: 1329: 1311: 1290: 1268: 1267: 1265: 1262: 1261: 1260: 1254: 1248: 1242: 1227: 1224: 1215: 1212: 1190: 1187: 1167: 1166: 1163: 1162: 1157: 1147: 1146: 1140: 1139: 1136: 1135: 1133: 1131: 1124: 1123: 1116: 1109: 1105: 1104: 1101: 1100: 1074: 1073: 1067: 1064: 1063: 1025: 1024: 998: 994: 993: 990: 989: 963: 962: 956: 953: 952: 914: 913: 887: 883: 882: 879: 878: 870: 869: 863: 860: 859: 851: 850: 844: 838: 837: 834: 833: 825: 824: 818: 815: 814: 806: 805: 799: 793: 792: 789: 788: 780: 779: 773: 770: 769: 761: 760: 754: 748: 747: 742: 737: 733: 732: 722: 721: 718: 717: 706: 705: 703: 702: 697: 692: 687: 682: 677: 671: 669: 665: 664: 662: 661: 656: 650: 648: 644: 643: 641: 640: 635: 630: 625: 620: 615: 610: 605: 599: 597: 593: 592: 582: 581: 578: 577: 574: 573: 565: 564: 553: 547: 546: 543: 542: 534: 533: 530: 529: 527: 526: 522: 518: 514: 510: 506: 502: 498: 494: 490: 489:tail of embryo 486: 483: 482: 471: 468: 467: 465: 464: 460: 456: 452: 448: 447:gastric mucosa 444: 440: 436: 432: 428: 424: 421: 420: 408: 407: 399: 388: 382: 381: 378:RNA expression 370: 369: 366: 365: 357: 353: 352: 344: 341: 336: 330: 329: 320: 313: 307: 303: 302: 297: 291: 290: 282: 281: 269: 268: 265: 264: 256: 252: 251: 243: 240: 235: 229: 228: 219: 212: 206: 202: 201: 194: 188: 187: 179: 178: 166: 165: 122: 118: 117: 109: 101: 100: 96: 95: 92: 91: 88: 87: 77: 76: 68: 67: 56: 50: 49: 41: 40: 37: 36: 28: 24: 14: 13: 10: 9: 6: 4: 3: 2: 2406: 2395: 2392: 2390: 2387: 2386: 2384: 2373: 2368: 2366: 2361: 2359: 2354: 2353: 2347: 2345: 2341: 2337: 2336:chromosome 18 2333: 2328: 2325: 2321: 2316: 2308: 2304: 2300: 2296: 2292: 2288: 2284: 2280: 2274: 2270: 2266: 2262: 2258: 2255:(3): 1012–5. 2254: 2250: 2245: 2241: 2237: 2232: 2227: 2223: 2219: 2215: 2211: 2207: 2202: 2198: 2194: 2190: 2186: 2182: 2178: 2174: 2170: 2164: 2160: 2156: 2152: 2148: 2144: 2140: 2136: 2132: 2131:Prenat. Diagn 2127: 2123: 2119: 2114: 2109: 2104: 2099: 2096:(9): 7021–8. 2095: 2091: 2090:J. Biol. Chem 2087: 2082: 2078: 2074: 2069: 2064: 2060: 2056: 2052: 2047: 2043: 2039: 2036:(9): 457–63. 2035: 2031: 2026: 2022: 2018: 2013: 2008: 2004: 2000: 1996: 1992: 1988: 1983: 1979: 1975: 1970: 1965: 1960: 1955: 1951: 1947: 1943: 1939: 1935: 1930: 1926: 1922: 1917: 1912: 1908: 1904: 1900: 1896: 1892: 1887: 1883: 1879: 1874: 1869: 1865: 1861: 1860:J. Biol. Chem 1857: 1852: 1848: 1844: 1839: 1834: 1830: 1826: 1825:J. Biol. Chem 1822: 1817: 1813: 1809: 1805: 1801: 1796: 1791: 1787: 1783: 1779: 1774: 1770: 1766: 1761: 1756: 1753:(5): 1080–5. 1752: 1748: 1744: 1739: 1735: 1731: 1727: 1723: 1719: 1715: 1712:(3): 219–23. 1711: 1707: 1702: 1698: 1694: 1689: 1684: 1680: 1676: 1673:(1): 97–111. 1672: 1668: 1664: 1659: 1658: 1653: 1644: 1640: 1636: 1632: 1627: 1622: 1618: 1614: 1610: 1603: 1600: 1595: 1591: 1586: 1581: 1577: 1573: 1572:J. Biol. Chem 1569: 1562: 1559: 1554: 1550: 1545: 1540: 1536: 1532: 1531:J. Biol. Chem 1528: 1521: 1519: 1515: 1510: 1506: 1501: 1496: 1491: 1486: 1482: 1478: 1474: 1470: 1466: 1459: 1457: 1453: 1448: 1442: 1440: 1436: 1431: 1427: 1423: 1419: 1415: 1414:10.1038/76074 1411: 1407: 1403: 1399: 1392: 1389: 1384: 1380: 1375: 1370: 1366: 1362: 1358: 1351: 1348: 1343: 1339: 1333: 1330: 1325: 1321: 1315: 1312: 1308: 1304: 1299: 1297: 1295: 1291: 1287: 1283: 1278: 1276: 1274: 1270: 1263: 1258: 1255: 1252: 1249: 1246: 1243: 1240: 1237: 1236: 1235: 1233: 1225: 1223: 1221: 1213: 1211: 1209: 1204: 1200: 1196: 1188: 1186: 1184: 1181: 1177: 1173: 1161: 1156: 1152: 1148: 1145: 1141: 1134: 1132: 1129: 1125: 1121: 1117: 1114: 1110: 1106: 1099: 1097: 1093: 1089: 1085: 1081: 1075: 1071: 1068: 1062: 1060: 1056: 1052: 1048: 1044: 1040: 1036: 1032: 1026: 1022: 1018: 1014: 1010: 1006: 1002: 999: 995: 988: 986: 982: 978: 974: 970: 964: 960: 957: 951: 949: 945: 941: 937: 933: 929: 925: 921: 915: 911: 907: 903: 899: 895: 891: 888: 886:RefSeq (mRNA) 884: 877: 876: 871: 867: 864: 858: 857: 852: 848: 845: 843: 839: 832: 831: 826: 822: 819: 813: 812: 807: 803: 800: 798: 794: 787: 786: 781: 777: 774: 768: 767: 762: 758: 755: 753: 749: 746: 743: 741: 738: 734: 731: 727: 723: 716: 712: 707: 701: 698: 696: 693: 691: 688: 686: 683: 681: 678: 676: 673: 672: 670: 667: 666: 660: 657: 655: 652: 651: 649: 646: 645: 639: 636: 634: 631: 629: 626: 624: 621: 619: 616: 614: 611: 609: 606: 604: 601: 600: 598: 595: 594: 591: 590:Gene ontology 587: 583: 571: 566: 562: 557: 554: 552: 548: 540: 535: 524: 520: 516: 512: 508: 504: 500: 496: 492: 488: 487: 484: 480: 475: 472: 462: 458: 454: 450: 446: 442: 438: 434: 430: 426: 425: 422: 418: 413: 410: 409: 406: 404: 400: 398: 397: 393: 392: 389: 387: 383: 379: 375: 371: 363: 358: 354: 350: 345: 335: 331: 324: 317: 311: 304: 296: 292: 288: 283: 279: 274: 270: 262: 257: 253: 249: 244: 234: 230: 223: 216: 210: 203: 199: 193: 189: 185: 180: 176: 171: 167: 163: 159: 155: 151: 147: 143: 139: 135: 131: 127: 119: 114: 107: 102: 97: 86: 84: 78: 73: 70: 69: 65: 62: 55: 51: 46: 42: 38: 33: 27: 19: 2344:expanding it 2329: 2314: 2285:(1): 43–51. 2282: 2278: 2252: 2248: 2213: 2209: 2175:(2): 131–4. 2172: 2168: 2134: 2130: 2113:10261/112516 2093: 2089: 2058: 2054: 2033: 2029: 1994: 1990: 1941: 1937: 1898: 1894: 1863: 1859: 1828: 1824: 1788:(1): 29–39. 1785: 1781: 1750: 1746: 1709: 1705: 1670: 1666: 1619:(1): 29–39. 1616: 1612: 1602: 1575: 1571: 1561: 1534: 1530: 1472: 1468: 1408:(2): 205–8. 1405: 1401: 1391: 1364: 1360: 1350: 1341: 1332: 1323: 1314: 1229: 1226:Interactions 1217: 1195:homeodomains 1192: 1179: 1171: 1170: 1092:NP_001157549 1088:NP_001157548 1084:NP_001157547 1080:NP_001157546 1077: 1059:NP_001361326 1055:NP_001361325 1028: 1013:NP_001265615 1009:NP_001265613 1005:NP_001265611 981:NM_001164077 977:NM_001164076 973:NM_001164075 969:NM_001164074 966: 948:NM_001374397 944:NM_001374396 917: 902:NM_001278686 898:NM_001278684 894:NM_001278682 873: 854: 828: 809: 783: 764: 744: 739: 513:otic placode 509:otic vesicle 401: 394: 121:External IDs 80: 26: 1361:J Biol Chem 659:nucleoplasm 603:DNA binding 431:gallbladder 360:71,160,541 347:71,151,200 99:Identifiers 2383:Categories 2279:Hum. Mutat 2210:Biochem. J 2169:Hum. Genet 2137:(1): 5–7. 1706:Hum. Genet 1309:, May 2017 1288:, May 2017 1264:References 405:(ortholog) 259:3,459,978 246:3,411,608 142:HomoloGene 2334:on human 1402:Nat Genet 1398:Zackai EH 1096:NP_033398 1051:NP_777480 1047:NP_775303 1043:NP_775302 1039:NP_775301 1035:NP_775300 1031:NP_775299 1021:NP_733796 1017:NP_003235 985:NM_009372 940:NM_174886 936:NM_173211 932:NM_173210 928:NM_173209 924:NM_173208 920:NM_173207 910:NM_170695 906:NM_003244 730:Orthologs 150:GeneCards 2307:34076824 2299:15221788 2269:12601022 2240:12593671 2189:12522553 2151:11810641 2122:11748221 2077:11682623 2042:11571228 2021:11416139 1978:11371641 1925:11226163 1882:10995736 1847:10764806 1804:10199400 1734:15442879 1697:16962354 1635:10199400 1594:11427533 1553:10995736 1509:11371641 1430:24723063 1422:10835638 1305:– 1284:– 1232:interact 1199:homeobox 1189:Function 1144:Wikidata 709:Sources: 517:epiblast 505:ectoderm 238:18p11.31 2231:1223316 2197:2238304 2159:8297098 1946:Bibcode 1812:6907878 1769:7485158 1760:1801375 1726:3192211 1688:1820763 1643:6907878 1477:Bibcode 1383:8537382 1307:Ensembl 1286:Ensembl 1197:. TALE 1176:protein 842:UniProt 797:Ensembl 736:Species 715:QuickGO 654:nucleus 497:saccule 380:pattern 138:1194497 106:Aliases 2305:  2297:  2267:  2238:  2228:  2195:  2187:  2157:  2149:  2120:  2075:  2040:  2019:  2009:  1976:  1966:  1923:  1916:140192 1913:  1895:EMBO J 1880:  1845:  1810:  1802:  1767:  1757:  1732:  1724:  1695:  1685:  1641:  1633:  1592:  1551:  1507:  1497:  1428:  1420:  1381:  1253:, and 1234:with: 1130:search 1128:PubMed 875:P70284 856:Q15583 752:Entrez 551:BioGPS 501:embryo 443:rectum 130:602630 2338:is a 2303:S2CID 2193:S2CID 2155:S2CID 2012:87125 1969:33445 1808:S2CID 1730:S2CID 1639:S2CID 1500:33445 1426:S2CID 1251:HDAC1 1245:CTBP1 1239:C-jun 1208:SMAD2 1180:TGIF1 1174:is a 785:21815 745:Mouse 740:Human 711:Amigo 403:Mouse 396:Human 343:Start 278:Mouse 242:Start 175:Human 154:TGIF1 113:TGIF1 35:TGIF1 18:TGIF1 2340:stub 2332:gene 2295:PMID 2265:PMID 2236:PMID 2185:PMID 2147:PMID 2118:PMID 2073:PMID 2038:PMID 2017:PMID 1974:PMID 1921:PMID 1878:PMID 1843:PMID 1800:PMID 1782:Cell 1765:PMID 1722:PMID 1693:PMID 1631:PMID 1613:Cell 1590:PMID 1549:PMID 1505:PMID 1418:PMID 1379:PMID 1183:gene 766:7050 386:Bgee 334:Band 295:Chr. 233:Band 192:Chr. 146:7574 126:OMIM 83:2LK2 64:RCSB 61:PDBe 2287:doi 2257:doi 2226:PMC 2218:doi 2214:371 2177:doi 2173:112 2139:doi 2108:hdl 2098:doi 2094:277 2063:doi 2007:PMC 1999:doi 1964:PMC 1954:doi 1911:PMC 1903:doi 1868:doi 1864:275 1833:doi 1829:275 1790:doi 1755:PMC 1714:doi 1683:PMC 1675:doi 1621:doi 1580:doi 1576:276 1539:doi 1535:275 1495:PMC 1485:doi 1410:doi 1369:doi 1365:270 521:lip 356:End 255:End 158:OMA 134:MGI 54:PDB 2385:: 2301:. 2293:. 2283:24 2281:. 2263:. 2253:44 2251:. 2234:. 2224:. 2212:. 2208:. 2191:. 2183:. 2171:. 2153:. 2145:. 2135:22 2133:. 2116:. 2106:. 2092:. 2088:. 2071:. 2059:15 2057:. 2053:. 2034:12 2032:. 2015:. 2005:. 1995:21 1993:. 1989:. 1972:. 1962:. 1952:. 1942:98 1940:. 1936:. 1919:. 1909:. 1899:20 1897:. 1893:. 1876:. 1862:. 1858:. 1841:. 1827:. 1823:. 1806:. 1798:. 1786:97 1784:. 1780:. 1763:. 1751:57 1749:. 1745:. 1728:. 1720:. 1710:80 1708:. 1691:. 1681:. 1671:90 1669:. 1665:. 1637:. 1629:. 1617:97 1615:. 1611:. 1588:. 1574:. 1570:. 1547:. 1533:. 1529:. 1517:^ 1503:. 1493:. 1483:. 1473:98 1471:. 1467:. 1455:^ 1438:^ 1424:. 1416:. 1406:25 1404:. 1377:. 1363:. 1359:. 1340:. 1322:. 1293:^ 1272:^ 713:/ 362:bp 349:bp 261:bp 248:bp 156:; 152:: 148:; 144:: 140:; 136:: 132:; 128:: 2371:e 2364:t 2357:v 2346:. 2309:. 2289:: 2271:. 2259:: 2242:. 2220:: 2199:. 2179:: 2161:. 2141:: 2124:. 2110:: 2100:: 2079:. 2065:: 2044:. 2023:. 2001:: 1980:. 1956:: 1948:: 1927:. 1905:: 1884:. 1870:: 1849:. 1835:: 1814:. 1792:: 1771:. 1736:. 1716:: 1699:. 1677:: 1645:. 1623:: 1596:. 1582:: 1555:. 1541:: 1511:. 1487:: 1479:: 1449:. 1432:. 1412:: 1385:. 1371:: 1344:. 1326:. 1259:. 1247:, 1241:, 280:) 177:) 160:: 20:)

Index

TGIF1
PDB
PDBe
RCSB
2LK2
Aliases
TGIF1
OMIM
602630
MGI
1194497
HomoloGene
7574
GeneCards
TGIF1
OMA
TGIF1 - orthologs
Human
Chromosome 18 (human)
Chr.
Chromosome 18 (human)
Chromosome 18 (human)
Genomic location for TGIF1
Genomic location for TGIF1
Band
bp
bp
Mouse
Chromosome 17 (mouse)
Chr.

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