1264:
242:
219:
1489:
1000:
871:
116:
141:
248:
147:
1789:. Bolding and asterisks below groups of sequence indicate that an amino acid is highly conserved at that position. Full sequences include that of Sumatra barb (PTe THAP3), Electric eel (EEl THAP3), Lake whitefish (CCL THAP3), Baby whale (BBr THAP3), Whale shark (ARa THAP3), White-spotted bamboo shark (RTy THAP3), and Thorny skate (CPl THAP3). Accession numbers as in ortholog table.
1775:
1496:
THAP3 protein sequence with annotated domains, predicted phosphorylation, glycosylation, and Yin-Yang sites. THAP represents the location of the THAP domain, and HBM represents the HCF1C binding motif. Yellow represents glycosylation sites (with scores over 0.5), green represents phosphorylation
3187:
Roussigne M, Kossida S, Lavigne AC, Clouaire T, Ecochard V, Glories A, et al. (February 2003). "The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase".
255:
154:
1271:
THAP3 aligned mRNA and amino acid sequences. Annotated with start and stop sites of translations, protein domains, and predicted post-translational modification sites.
567:
548:
77:
2839:
3010:
2992:
4896:
3475:
2726:
3912:
Blom N, Gammeltoft S, Brunak S (December 1999). "Sequence and structure-based prediction of eukaryotic protein phosphorylation sites".
3093:"AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models"
241:
818:
2834:
2663:
940:
811:
218:
1785:
THAP3 (HSa THAP3; accession number NP 001182681.1) with distant orthologs. Boxing represents the location of the THAP domain in
2979:
2958:
3348:"Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics"
2902:
2898:
2975:
2235:
140:
115:
2876:
2954:
2764:
57:
254:
153:
1263:
2819:
2704:
2659:
2046:
1607:
1508:
247:
146:
2906:
2709:
2554:
612:
65:
4814:
1488:
999:
1128:
936:
593:
4076:"Classification of the human THAP protein family identifies an evolutionarily conserved coiled coil region"
3242:"THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves"
870:
2630:
2331:
1599:
3897:
Prediction of glycosylation sites in proteomes: from post-translational modifications to protein function
2362:
2266:
2204:
2015:
1964:
3346:
Fagerberg L, Hallström BM, Oksvold P, Kampf C, Djureinovic D, Odeberg J, et al. (February 2014).
3639:
3410:
3292:
3044:
2881:
2861:
2844:
2824:
2807:
2790:
2731:
2714:
1336:
1140:
129:
44:
4253:"Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega"
2743:
2667:
1982:
928:
790:
765:
761:
731:
710:
706:
702:
692:
688:
680:
676:
4650:"THAP domain-containing protein 3 isoform X1 [Brienomyrus brachyistius] - Protein - NCBI"
4614:"THAP domain-containing protein 3 isoform X1 [Electrophorus electricus] - Protein - NCBI"
2297:
89:
4790:
4704:"THAP domain-containing protein 3 isoform X1 [Chiloscyllium plagiosum] - Protein - NCBI"
4027:"Regulation of transcription factor activity by interconnected post-translational modifications"
2458:
1945:
THAP3, and 41.3-54.1% similarity in organisms that are distantly related, diverged 431-464 MYA.
794:
769:
735:
684:
4632:"THAP domain-containing protein 3 isoform X1 [Coregonus clupeaformis] - Protein - NCBI"
4578:"THAP domain-containing protein 3 isoform X1 [Microcaecilia unicolor] - Protein - NCBI"
4542:"THAP domain-containing protein 3 isoform X1 [Chelonoidis abingdonii] - Protein - NCBI"
4488:"THAP domain-containing protein 3 isoform X1 [Phascolarctos cinereus] - Protein - NCBI"
3091:
Varadi M, Anyango S, Deshpande M, Nair S, Natassia C, Yordanova G, et al. (January 2022).
1143:
and 3 are unspliced. Variant 1 is the predominant variant and encodes THAP3 protein isoform 1.
4872:
4596:"THAP domain-containing protein 3 isoform X1 [Geotrypetes seraphini] - Protein - NCBI"
4452:"THAP domain-containing protein 3 isoform X1 [Balaenoptera musculus] - Protein - NCBI"
4355:
4282:
4107:
4056:
3983:
3929:
3873:
3667:
3436:
3379:
3271:
3205:
3122:
3070:
2785:
2773:
2752:
2463:
1925:
1906:
1894:
1872:
1828:
1794:
1658:
1294:
37:
4470:"THAP domain-containing protein 3 isoform X1 [Dromiciops gliroides] - Protein - NCBI"
4398:"THAP domain-containing protein 3 isoform X1 [Marmota flaviventris] - Protein - NCBI"
3031:
Jumper J, Evans R, Pritzel A, Green T, Figurnov M, Ronneberger O, et al. (August 2021).
1939:
Sequences that diverged 319-353 MYA, those moderately related, have 47.2-68.9% similarity to
4862:
4854:
4668:"THAP domain-containing protein 3 isoform X1 [Puntigrus tetrazona] - Protein - NCBI"
4345:
4337:
4324:
Kumar S, Suleski M, Craig JM, Kasprowicz AE, Sanderford M, Li M, et al. (August 2022).
4272:
4264:
4097:
4087:
4046:
4038:
3973:
3963:
3921:
3863:
3855:
3657:
3647:
3592:"Homo sapiens THAP domain containing 3 (THAP3), transcript variant 7, m - Nucleotide - NCBI"
3532:"Homo sapiens THAP domain containing 3 (THAP3), transcript variant 3, m - Nucleotide - NCBI"
3514:"Homo sapiens THAP domain containing 3 (THAP3), transcript variant 2, m - Nucleotide - NCBI"
3426:
3418:
3369:
3359:
3261:
3253:
3197:
3112:
3104:
3060:
3052:
2926:
2922:
2769:
2748:
2139:
1520:
1512:
1117:
1104:
1027:
334:
265:
209:
164:
3950:
Wang J, Youkharibache P, Marchler-Bauer A, Lanczycki C, Zhang D, Lu S, et al. (2022).
85:
4722:"THAP domain-containing protein 3 isoform X1 [Amblyraja radiata] - Protein - NCBI"
4524:"THAP domain-containing protein 3 isoform X1 [Gopherus evgoodei] - Protein - NCBI"
4416:"THAP domain-containing protein 3 isoform X1 [Lontra canadensis] - Protein - NCBI"
3163:
2871:
1975:
1959:
1864:
1860:
1804:
1611:
1595:
1340:
1087:
1079:
1075:
1043:
1039:
1031:
944:
309:
4434:"THAP domain-containing protein 3 isoform X1 [Eptesicus fuscus] - Protein - NCBI"
3684:
Gasteiger E., Hoogland C., Gattiker A., Duvaud S., Wilkins M.R., Appel R.D., Bairoch A.;
2909:
movement disorder that predominantly affects males of
Filipino descent. Symptoms include
4686:"THAP domain-containing protein 3 isoform X1 [Rhincodon typus] - Protein - NCBI"
4560:"THAP domain-containing protein 3 isoform X1 [Mauremys mutica] - Protein - NCBI"
4506:"THAP domain-containing protein 3 isoform X1 [Caretta caretta] - Protein - NCBI"
3643:
3414:
3048:
4867:
4842:
4350:
4325:
4277:
4252:
4102:
4075:
4051:
4026:
3978:
3951:
3868:
3843:
3431:
3398:
3374:
3347:
3266:
3241:
3117:
3092:
3065:
3032:
2655:
2513:
2427:
2144:
1824:
1654:
1646:
1573:
1528:
1324:
1314:
1286:
932:
924:
4721:
4703:
4685:
4667:
4649:
4631:
4613:
4595:
4577:
4559:
4541:
4523:
4505:
4487:
4469:
4451:
4433:
4415:
4397:
4300:
3824:
3806:
3788:
3770:
3752:
3734:
3698:
3591:
3531:
3201:
4890:
4251:
Sievers F, Wilm A, Dineen D, Gibson TJ, Karplus K, Li W, et al. (October 2011).
3662:
3627:
3609:
3577:
3563:
3549:
3499:
3319:
3223:
2634:
2494:
2401:
2175:
2077:
1615:
1564:
1290:
1136:
1091:
1063:
4301:"THAP domain-containing protein 3 isoform 1 [Homo sapiens] - Protein - NCBI"
3859:
3844:"IBS: an illustrator for the presentation and visualization of biological sequences"
3825:"THAP domain-containing protein 3 isoform 8 [Homo sapiens] - Protein - NCBI"
3807:"THAP domain-containing protein 3 isoform 7 [Homo sapiens] - Protein - NCBI"
3789:"THAP domain-containing protein 3 isoform 6 [Homo sapiens] - Protein - NCBI"
3771:"THAP domain-containing protein 3 isoform 5 [Homo sapiens] - Protein - NCBI"
3753:"THAP domain-containing protein 3 isoform 4 [Homo sapiens] - Protein - NCBI"
3735:"THAP domain-containing protein 3 isoform 3 [Homo sapiens] - Protein - NCBI"
3717:"THAP domain-containing protein 3 isoform 2 [Homo sapiens] - Protein - NCBI"
3699:"THAP domain-containing protein 3 isoform 1 [Homo sapiens] - Protein - NCBI"
3320:"THAP domain-containing protein 3 isoform 1 [Homo sapiens] - Protein - NCBI"
69:
3716:
3513:
3397:
Duff MO, Olson S, Wei X, Garrett SC, Osman A, Bolisetty M, et al. (May 2015).
2585:
2559:
2528:
2396:
2386:
1852:
1820:
1560:
985:
327:
106:
4739:
4373:
3688:(In) John M. Walker (ed): The Proteomics Protocols Handbook, Humana Press (2005).
93:
3399:"Genome-wide identification of zero nucleotide recursive splicing in Drosophila"
3015:
National Center for
Biotechnology Information, U.S. National Library of Medicine
2997:
National Center for
Biotechnology Information, U.S. National Library of Medicine
2914:
2671:
2523:
1969:
1536:
1516:
4843:"X-linked dystonia parkinsonism: clinical phenotype, genetics and therapeutics"
4042:
3632:
Proceedings of the
National Academy of Sciences of the United States of America
3056:
410:
4092:
3968:
2918:
2590:
2489:
2432:
2108:
1914:
1886:
1540:
1532:
1524:
1302:
1298:
226:
123:
73:
4341:
4234:"THAP9 THAP domain containing 9 [Homo sapiens (human)] - Gene - NCBI"
4216:"THAP8 THAP domain containing 8 [Homo sapiens (human)] - Gene - NCBI"
4198:"THAP7 THAP domain containing 7 [Homo sapiens (human)] - Gene - NCBI"
4180:"THAP6 THAP domain containing 6 [Homo sapiens (human)] - Gene - NCBI"
4162:"THAP5 THAP domain containing 5 [Homo sapiens (human)] - Gene - NCBI"
4144:"THAP2 THAP domain containing 2 [Homo sapiens (human)] - Gene - NCBI"
4126:"THAP1 THAP domain containing 1 [Homo sapiens (human)] - Gene - NCBI"
3164:"THAP3 THAP domain containing 3 [Homo sapiens (human)] - Gene - NCBI"
3364:
2621:
2367:
2336:
2321:
2051:
1902:
1898:
1816:
989:
908:
512:
470:
348:
293:
280:
192:
179:
81:
4876:
4359:
4286:
4215:
4179:
4161:
4111:
4060:
3987:
3952:"iCn3D: From Web-Based 3D Viewer to Structural Analysis Tool in Batch Mode"
3933:
3925:
3877:
3652:
3610:"Homo sapiens THAP domain containing 3 (THAP3), transcript variant 8, mRNA"
3578:"Homo sapiens THAP domain containing 3 (THAP3), transcript variant 6, mRNA"
3564:"Homo sapiens THAP domain containing 3 (THAP3), transcript variant 5, mRNA"
3550:"Homo sapiens THAP domain containing 3 (THAP3), transcript variant 4, mRNA"
3500:"Homo sapiens THAP domain containing 3 (THAP3), transcript variant 1, mRNA"
3440:
3383:
3275:
3224:"Homo sapiens THAP domain containing 3 (THAP3), transcript variant 1, mRNA"
3209:
3126:
3108:
3074:
1497:
sites (with scores over 0.75), and diamond shapes represent Yin-Yang sites.
992:
long, spanning from genomic coordinates 6,624,868-6,635,595. It contains 6
4233:
4197:
4143:
4125:
3671:
1774:
858:
853:
3626:
Brendel V, Bucher P, Nourbakhsh IR, Blaisdell BE, Karlin S (March 1992).
2930:
1921:
1890:
1832:
1310:
1306:
1059:
1055:
920:
842:
657:
638:
4268:
3422:
4858:
2651:
2194:
2113:
1868:
1844:
1840:
1812:
1650:
1642:
1638:
1603:
1591:
1282:
1047:
977:
916:
912:
904:
890:
624:
579:
3628:"Methods and algorithms for statistical analysis of protein sequences"
3257:
1924:, those diverged 0-160 million years ago (MYA), percent similarity of
3842:
Liu W, Xie Y, Ma J, Luo X, Nie P, Zuo Z, et al. (October 2015).
2910:
2856:
2802:
2302:
2271:
2240:
2209:
2020:
2005:
1929:
1882:
1836:
1808:
1114:
1083:
1067:
1035:
955:
826:
534:
4763:
3240:
Sabogal A, Lyubimov AY, Corn JE, Berger JM, Rio DC (January 2010).
4001:
2646:
2626:
2616:
2170:
1941:
1934:
1877:
1848:
1799:
1663:
1633:
1586:
1569:
1503:
1319:
1277:
1109:
1101:
1096:
1071:
1051:
1018:
968:
949:
895:
3293:"Entry - *612532 - THAP Doman-Containing Protein 3; THAP3 - OMIM"
1910:
1856:
1132:
1023:
993:
981:
973:
900:
61:
4326:"TimeTree 5: An Expanded Resource for Species Divergence Times"
3686:
3476:"Protein BLAST: search protein databases using a protein query"
907:
is as known as MGC33488, LOC90326, and THAP domain-containing,
4374:"EMBOSS Needle < Pairwise Sequence Alignment < EMBL-EBI"
2082:
3033:"Highly accurate protein structure prediction with AlphaFold"
1543:
186-230 and contains the host-cell factor 1C binding motif.
935:
allow THAP3 to influence a variety of processes, including
4815:"THAP3 Gene - GeneCards | THAP3 Protein | THAP3 Antibody"
1803:
THAP3. Orthologs can be found in a variety of taxomonic
1327:(THAP) and the hell-cell factor 1C binding motif (HCM).
317:
4074:
Sanghavi HM, Mallajosyula SS, Majumdar S (March 2019).
482:
783:
754:
724:
675:
2971:
2969:
2967:
2950:
2948:
2946:
1527:of the sequence and is the structure of the THAP
264:
163:
1893:(lizards and snakes). Similarly, there are only
1050:and male and female sexual organs, such as the
1026:is expressed ubiquitously throughout different
2976:GRCm38: Ensembl release 89: ENSMUSG00000039759
1778:Multiple sequence alignment of THAP domain in
988:at cytogenetic location 1p36.31. It is 10,727
3612:. April 22, 2022 – via NCBI Nucleotide.
3580:. April 22, 2022 – via NCBI Nucleotide.
3566:. April 22, 2022 – via NCBI Nucleotide.
3552:. April 22, 2022 – via NCBI Nucleotide.
3502:. April 22, 2022 – via NCBI Nucleotide.
1602:sites, and 11 predicted Yin-Yang sites. Many
8:
4238:National Center of Biotechnology Information
4220:National Center of Biotechnology Information
4202:National Center of Biotechnology Information
4184:National Center of Biotechnology Information
4166:National Center of Biotechnology Information
4148:National Center of Biotechnology Information
4130:National Center of Biotechnology Information
4025:Filtz TM, Vogel WK, Leid M (February 2014).
3480:National Center of Biotechnology Information
3324:National Center of Biotechnology Information
1618:sites, which corroborates THAP3's function.
2955:GRCh38: Ensembl release 89: ENSG00000041988
2933:, which typically develops later in life.
1947:
672:
508:
305:
204:
101:
4866:
4349:
4276:
4101:
4091:
4050:
3977:
3967:
3867:
3661:
3651:
3430:
3373:
3363:
3265:
3246:Nature Structural & Molecular Biology
3116:
3064:
2897:THAP3 contributes to the presentation of
1928:ranges from 36-82.9%. THAP3 sequences in
2676:
1885:(turtles or tortoises) and not found in
1773:
1669:
1487:
1345:
1262:
1145:
1042:of THAP3 tends to be slightly higher in
998:
869:
2942:
4785:
4783:
3945:
3943:
3907:
3905:
3470:
3235:
3233:
984:that is located on the plus strand of
18:
4836:
4834:
3891:
3889:
3887:
3621:
3619:
3468:
3466:
3464:
3462:
3460:
3458:
3456:
3454:
3452:
3450:
3341:
3339:
3314:
3312:
3287:
3285:
3158:
3156:
3086:
3084:
269:
230:
225:
168:
127:
122:
7:
3154:
3152:
3150:
3148:
3146:
3144:
3142:
3140:
3138:
3136:
3026:
3024:
1932:are the least conserved compared to
954:though expression is highest in the
3352:Molecular & Cellular Proteomics
1038:. It has also been determined that
1007:(human) THAP3 gene on chromosome 1.
4031:Trends in Pharmacological Sciences
3956:Frontiers in Molecular Biosciences
3899:. Technical University of Denmark.
899:(humans), is encoded by the THAP3
780:
751:
721:
648:
629:
603:
584:
558:
539:
487:
405:
343:
322:
14:
4791:"THAP3 Result Summary | BioGRID"
883:THAP domain-containing protein 3
874:Predicted Tertiary Structure of
253:
246:
240:
217:
152:
145:
139:
114:
4330:Molecular Biology and Evolution
1889:(crocodiles and alligators) or
1151:THAP3 mRNA transcript variants
3190:Trends in Biochemical Sciences
2899:X-linked Dystonia-Parkinsonism
2267:Abingdon Island giant tortoise
1580:Post-translation modifications
1359:Sequence length (amino acids)
1159:Sequence length (nucleotides)
1086:is 1.4-1.5x higher than those
471:More reference expression data
363:right hemisphere of cerebellum
1:
4847:Journal of Movement Disorders
3860:10.1093/bioinformatics/btv362
3202:10.1016/S0968-0004(02)00013-0
238:
137:
3914:Journal of Molecular Biology
2666:. It is also interacts with
1793:There are approximately 206
1339:variants, there are 8 THAP3
4897:Genes on human chromosome 1
4841:Rosales RL (October 2010).
2681:THAP3 Protein Interactions
2633:, which is involved in the
2236:Goode's thornscrub tortoise
1999:Percent Similarity to THAP3
1641:, along with several other
1523:region is located near the
1135:can result in 11 different
923:-associated protein (THAP)
4913:
4043:10.1016/j.tips.2013.11.005
3057:10.1038/s41586-021-03819-2
2555:White-spotted bamboo shark
2047:North American river otter
1863:are represented with in a
1686:Percent Identity to THAP3
1267:Conceptual translation of
1094:is 1.3x. more abundant in
449:sternocleidomastoid muscle
367:mucosa of transverse colon
48:, THAP domain containing 3
4257:Molecular Systems Biology
4093:10.1186/s12900-019-0102-2
3969:10.3389/fmolb.2022.831740
3011:"Mouse PubMed Reference:"
2993:"Human PubMed Reference:"
1994:Percent Identity to THAP3
1139:variants, of which 8 are
857:
852:
848:
841:
825:
819:Chr 4: 152.07 – 152.07 Mb
806:
787:
758:
747:
728:
699:
668:
655:
651:
636:
632:
623:
610:
606:
591:
587:
578:
565:
561:
546:
542:
533:
518:
511:
507:
495:
490:
481:
468:
453:quadriceps femoris muscle
417:
408:
355:
346:
316:
308:
304:
287:
274:
237:
216:
207:
203:
186:
173:
136:
113:
104:
100:
55:
52:
42:
35:
30:
26:
21:
2705:Transcription Regulation
2660:transcription regulation
2454:Brienomyrus brachyistius
2392:Electrophorus electricus
1859:. Additionally, not all
1827:. However, there are no
1608:transcription regulation
1559:can be localized in the
943:. THAP3 is ubiquitously
3365:10.1074/mcp.M113.035600
2550:Chiloscyllium plagiosum
1285:is predicted to have a
457:vastus lateralis muscle
4342:10.1093/molbev/msac174
4080:BMC Structural Biology
3926:10.1006/jmbi.1999.3310
3653:10.1073/pnas.89.6.2002
3097:Nucleic Acids Research
2423:Coregonus clupeaformis
2332:Microcaecilia unicolor
2327:Microcaecilia unicolor
2262:Chelonoidis abingdonii
2166:Phascolarctos cinereus
1790:
1645:, is part of the THAP
1622:Homology and evolution
1498:
1313:poor. Characteristics
1272:
1147:Alternatively spliced
1008:
879:
441:skeletal muscle tissue
437:triceps brachii muscle
4002:"PSORT II Prediction"
2893:Clinical significance
2650:THAP3 interacts with
2624:at a rate similar to
2358:Geotrypetes seraphini
2104:Balaenoptera musculus
2016:Yellow-bellied marmot
1777:
1491:
1337:alternatively spliced
1266:
1141:alternatively spliced
1003:Gene neighborhood of
1002:
931:binding motif. These
873:
812:Chr 1: 6.62 – 6.64 Mb
4726:www.ncbi.nlm.nih.gov
4708:www.ncbi.nlm.nih.gov
4690:www.ncbi.nlm.nih.gov
4672:www.ncbi.nlm.nih.gov
4654:www.ncbi.nlm.nih.gov
4636:www.ncbi.nlm.nih.gov
4618:www.ncbi.nlm.nih.gov
4600:www.ncbi.nlm.nih.gov
4582:www.ncbi.nlm.nih.gov
4564:www.ncbi.nlm.nih.gov
4546:www.ncbi.nlm.nih.gov
4528:www.ncbi.nlm.nih.gov
4510:www.ncbi.nlm.nih.gov
4492:www.ncbi.nlm.nih.gov
4474:www.ncbi.nlm.nih.gov
4456:www.ncbi.nlm.nih.gov
4438:www.ncbi.nlm.nih.gov
4420:www.ncbi.nlm.nih.gov
4402:www.ncbi.nlm.nih.gov
4305:www.ncbi.nlm.nih.gov
3829:www.ncbi.nlm.nih.gov
3811:www.ncbi.nlm.nih.gov
3793:www.ncbi.nlm.nih.gov
3775:www.ncbi.nlm.nih.gov
3757:www.ncbi.nlm.nih.gov
3739:www.ncbi.nlm.nih.gov
3721:www.ncbi.nlm.nih.gov
3703:www.ncbi.nlm.nih.gov
3596:www.ncbi.nlm.nih.gov
3536:www.ncbi.nlm.nih.gov
3518:www.ncbi.nlm.nih.gov
3168:www.ncbi.nlm.nih.gov
3109:10.1093/nar/gkab1061
2923:postural instability
2905:. This disease is a
2835:Neuronal Development
2668:molecular chaperones
2664:neuronal development
2654:involved in various
2641:Protein interactions
2514:Cartilaginous Fishes
2135:Dromiciops gliroides
2011:Marmota flaviventris
1825:cartilaginous fishes
1598:sites, 28 predicted
941:neuronal development
379:right adrenal cortex
232:Chromosome 4 (mouse)
130:Chromosome 1 (human)
4269:10.1038/msb.2011.75
3644:1992PNAS...89.2002B
3423:10.1038/nature14475
3415:2015Natur.521..376D
3049:2021Natur.596..583J
2682:
2485:Puntigrus tetrazona
1954:
1920:In closely related
1881:THAP3 are found in
1676:
1352:
1152:
1034:is greatest in the
929:host-cell factor 1C
375:canal of the cervix
4859:10.14802/jmd.10009
3895:Gupta, R. (2001).
2677:
2656:cellular processes
2298:Yellow pond turtle
1948:
1867:. For example, in
1791:
1670:
1647:family of proteins
1610:are influenced by
1509:tertiary structure
1499:
1346:
1273:
1146:
1009:
880:
613:ENSMUSG00000039759
4819:www.genecards.org
3854:(20): 3359–3361.
3409:(7552): 376–379.
3258:10.1038/nsmb.1742
3103:(D1): D439–D444.
3043:(7873): 583–589.
2907:neurodegenerative
2890:
2889:
2774:mass spectrometry
2753:mass spectrometry
2608:
2607:
2581:Amblyraja radiata
2464:Osteoglossiformes
2231:Gopherus evgoodei
2205:Loggerhead turtle
2042:Lontra canadensis
1767:
1766:
1653:contain the THAP
1600:O-β-glycosylation
1594:has 30 predicted
1481:
1480:
1362:Accession number
1256:
1255:
868:
867:
864:
863:
837:
836:
802:
801:
777:
776:
743:
742:
718:
717:
664:
663:
645:
644:
619:
618:
600:
599:
574:
573:
555:
554:
503:
502:
499:
498:
477:
476:
464:
463:
402:
401:
300:
299:
199:
198:
94:THAP3 - orthologs
16:Protein in Humans
4904:
4881:
4880:
4870:
4838:
4829:
4828:
4826:
4825:
4811:
4805:
4804:
4802:
4801:
4787:
4778:
4777:
4775:
4774:
4760:
4754:
4753:
4751:
4750:
4736:
4730:
4729:
4718:
4712:
4711:
4700:
4694:
4693:
4682:
4676:
4675:
4664:
4658:
4657:
4646:
4640:
4639:
4628:
4622:
4621:
4610:
4604:
4603:
4592:
4586:
4585:
4574:
4568:
4567:
4556:
4550:
4549:
4538:
4532:
4531:
4520:
4514:
4513:
4502:
4496:
4495:
4484:
4478:
4477:
4466:
4460:
4459:
4448:
4442:
4441:
4430:
4424:
4423:
4412:
4406:
4405:
4394:
4388:
4387:
4385:
4384:
4370:
4364:
4363:
4353:
4321:
4315:
4314:
4312:
4311:
4297:
4291:
4290:
4280:
4248:
4242:
4241:
4230:
4224:
4223:
4212:
4206:
4205:
4194:
4188:
4187:
4176:
4170:
4169:
4158:
4152:
4151:
4140:
4134:
4133:
4122:
4116:
4115:
4105:
4095:
4071:
4065:
4064:
4054:
4022:
4016:
4015:
4013:
4012:
3998:
3992:
3991:
3981:
3971:
3947:
3938:
3937:
3920:(5): 1351–1362.
3909:
3900:
3893:
3882:
3881:
3871:
3839:
3833:
3832:
3821:
3815:
3814:
3803:
3797:
3796:
3785:
3779:
3778:
3767:
3761:
3760:
3749:
3743:
3742:
3731:
3725:
3724:
3713:
3707:
3706:
3695:
3689:
3682:
3676:
3675:
3665:
3655:
3638:(6): 2002–2006.
3623:
3614:
3613:
3606:
3600:
3599:
3598:. 22 April 2022.
3588:
3582:
3581:
3574:
3568:
3567:
3560:
3554:
3553:
3546:
3540:
3539:
3528:
3522:
3521:
3520:. 22 April 2022.
3510:
3504:
3503:
3496:
3490:
3489:
3487:
3486:
3472:
3445:
3444:
3434:
3394:
3388:
3387:
3377:
3367:
3343:
3334:
3333:
3331:
3330:
3316:
3307:
3306:
3304:
3303:
3289:
3280:
3279:
3269:
3237:
3228:
3227:
3220:
3214:
3213:
3184:
3178:
3177:
3175:
3174:
3160:
3131:
3130:
3120:
3088:
3079:
3078:
3068:
3028:
3019:
3018:
3007:
3001:
3000:
2989:
2983:
2973:
2962:
2952:
2901:, also known as
2882:two hybrid assay
2862:two hybrid assay
2845:two hybrid assay
2825:two hybrid assay
2808:two hybrid assay
2791:two hybrid assay
2770:affinity capture
2749:affinity capture
2732:two hybrid assay
2715:two hybrid assay
2698:Interaction Type
2683:
2631:fibrinogen alpha
2560:Orectolobiformes
2529:Orectolobiformes
2363:Gaboon caecilian
2140:Colocolo opossum
2073:Eptesicus fuscus
1989:Accession Number
1955:
1677:
1539:is located from
1353:
1335:Due to having 8
1287:molecular weight
1163:Accession number
1153:
850:
849:
821:
814:
797:
781:
772:
752:
748:RefSeq (protein)
738:
722:
713:
673:
649:
630:
604:
585:
559:
540:
509:
488:
473:
413:
411:Top expressed in
406:
387:popliteal artery
351:
349:Top expressed in
344:
323:
306:
296:
283:
272:
257:
250:
244:
233:
221:
205:
195:
182:
171:
156:
149:
143:
132:
118:
102:
96:
47:
40:
19:
4912:
4911:
4907:
4906:
4905:
4903:
4902:
4901:
4887:
4886:
4885:
4884:
4840:
4839:
4832:
4823:
4821:
4813:
4812:
4808:
4799:
4797:
4789:
4788:
4781:
4772:
4770:
4764:"IntAct Portal"
4762:
4761:
4757:
4748:
4746:
4744:www.uniprot.org
4738:
4737:
4733:
4720:
4719:
4715:
4702:
4701:
4697:
4684:
4683:
4679:
4666:
4665:
4661:
4648:
4647:
4643:
4630:
4629:
4625:
4612:
4611:
4607:
4594:
4593:
4589:
4576:
4575:
4571:
4558:
4557:
4553:
4540:
4539:
4535:
4522:
4521:
4517:
4504:
4503:
4499:
4486:
4485:
4481:
4468:
4467:
4463:
4450:
4449:
4445:
4432:
4431:
4427:
4414:
4413:
4409:
4396:
4395:
4391:
4382:
4380:
4372:
4371:
4367:
4323:
4322:
4318:
4309:
4307:
4299:
4298:
4294:
4250:
4249:
4245:
4232:
4231:
4227:
4214:
4213:
4209:
4196:
4195:
4191:
4178:
4177:
4173:
4160:
4159:
4155:
4142:
4141:
4137:
4124:
4123:
4119:
4073:
4072:
4068:
4024:
4023:
4019:
4010:
4008:
4000:
3999:
3995:
3949:
3948:
3941:
3911:
3910:
3903:
3894:
3885:
3841:
3840:
3836:
3823:
3822:
3818:
3805:
3804:
3800:
3787:
3786:
3782:
3769:
3768:
3764:
3751:
3750:
3746:
3733:
3732:
3728:
3715:
3714:
3710:
3697:
3696:
3692:
3683:
3679:
3625:
3624:
3617:
3608:
3607:
3603:
3590:
3589:
3585:
3576:
3575:
3571:
3562:
3561:
3557:
3548:
3547:
3543:
3538:. 10 June 2022.
3530:
3529:
3525:
3512:
3511:
3507:
3498:
3497:
3493:
3484:
3482:
3474:
3473:
3448:
3396:
3395:
3391:
3345:
3344:
3337:
3328:
3326:
3318:
3317:
3310:
3301:
3299:
3291:
3290:
3283:
3239:
3238:
3231:
3222:
3221:
3217:
3186:
3185:
3181:
3172:
3170:
3162:
3161:
3134:
3090:
3089:
3082:
3030:
3029:
3022:
3009:
3008:
3004:
2991:
2990:
2986:
2974:
2965:
2953:
2944:
2939:
2895:
2872:Protein Folding
2643:
2613:
2598:XP_032904038.1
2567:XP_043531920.1
2536:XP_020386430.1
2519:Rhincodon typus
2502:XP_043081346.1
2471:XP_048872538.1
2440:XP_041712304.2
2409:XP_026873261.2
2375:XP_033777236.1
2344:XP_030041702.1
2310:XP_044852367.1
2293:Mauremys mutica
2279:XP_032619750.1
2248:XP_030393185.1
2217:XP_048680971.1
2200:Caretta caretta
2183:XP_020830574.1
2152:XP_043850206.1
2121:XP_036686252.1
2090:XP_028016747.1
2059:XP_032719186.1
2028:XP_027803226.1
1965:Scientific Name
1917:(salamanders).
1905:. There are no
1772:
1657:and are, thus,
1649:. All of these
1629:
1624:
1612:phosphorylation
1596:phosphorylation
1582:
1554:
1549:
1486:
1474:NP_001381429.1
1460:NP_001381428.1
1446:NP_001381427.1
1432:NP_001381426.1
1418:NP_001381425.1
1404:NP_001182682.1
1376:NP_001182681.1
1333:
1261:
1252:NM_001394500.1
1241:NM_001394499.1
1230:NM_001394498.1
1219:NM_001394497.1
1208:NM_001394496.1
1197:NM_001195753.2
1175:NM_001195752.2
1126:
1046:located in the
1014:
964:
859:View/Edit Mouse
854:View/Edit Human
817:
810:
807:Location (UCSC)
793:
789:
768:
764:
760:
734:
730:
709:
705:
701:
695:
691:
687:
683:
679:
594:ENSG00000041988
469:
460:
455:
451:
447:
445:temporal muscle
443:
439:
435:
431:
429:muscle of thigh
427:
423:
409:
398:
393:
391:tibial arteries
389:
385:
381:
377:
373:
369:
365:
361:
347:
291:
278:
270:
260:
259:
258:
251:
231:
208:Gene location (
190:
177:
169:
159:
158:
157:
150:
128:
105:Gene location (
56:
43:
36:
17:
12:
11:
5:
4910:
4908:
4900:
4899:
4889:
4888:
4883:
4882:
4830:
4806:
4795:thebiogrid.org
4779:
4755:
4731:
4713:
4695:
4677:
4659:
4641:
4623:
4605:
4587:
4569:
4551:
4533:
4515:
4497:
4479:
4461:
4443:
4425:
4407:
4389:
4365:
4336:(8): msac174.
4316:
4292:
4243:
4225:
4207:
4189:
4171:
4153:
4135:
4117:
4066:
4017:
3993:
3939:
3901:
3883:
3848:Bioinformatics
3834:
3816:
3798:
3780:
3762:
3744:
3726:
3708:
3690:
3677:
3615:
3601:
3583:
3569:
3555:
3541:
3523:
3505:
3491:
3446:
3389:
3358:(2): 397–406.
3335:
3308:
3281:
3252:(1): 117–123.
3229:
3215:
3179:
3132:
3080:
3020:
3002:
2984:
2963:
2941:
2940:
2938:
2935:
2927:shuffling gait
2903:Lubag Syndrome
2894:
2891:
2888:
2887:
2886:Developmental
2884:
2879:
2874:
2868:
2867:
2864:
2859:
2854:
2851:
2850:
2847:
2842:
2837:
2831:
2830:
2827:
2822:
2817:
2814:
2813:
2810:
2805:
2800:
2797:
2796:
2793:
2788:
2783:
2780:
2779:
2776:
2767:
2762:
2759:
2758:
2755:
2746:
2741:
2738:
2737:
2734:
2729:
2724:
2721:
2720:
2717:
2712:
2707:
2701:
2700:
2695:
2693:Identified By!
2690:
2687:
2642:
2639:
2612:
2609:
2606:
2605:
2602:
2599:
2596:
2593:
2588:
2583:
2578:
2575:
2574:
2571:
2568:
2565:
2562:
2557:
2552:
2547:
2544:
2543:
2540:
2537:
2534:
2531:
2526:
2521:
2516:
2510:
2509:
2506:
2503:
2500:
2497:
2492:
2487:
2482:
2479:
2478:
2475:
2472:
2469:
2466:
2461:
2456:
2451:
2448:
2447:
2444:
2441:
2438:
2435:
2430:
2428:Lake whitefish
2425:
2420:
2417:
2416:
2413:
2410:
2407:
2404:
2399:
2394:
2389:
2383:
2382:
2379:
2376:
2373:
2370:
2365:
2360:
2355:
2352:
2351:
2348:
2345:
2342:
2339:
2334:
2329:
2324:
2318:
2317:
2314:
2311:
2308:
2305:
2300:
2295:
2290:
2287:
2286:
2283:
2280:
2277:
2274:
2269:
2264:
2259:
2256:
2255:
2252:
2249:
2246:
2243:
2238:
2233:
2228:
2225:
2224:
2221:
2218:
2215:
2212:
2207:
2202:
2197:
2191:
2190:
2187:
2184:
2181:
2178:
2173:
2168:
2163:
2160:
2159:
2156:
2153:
2150:
2147:
2145:Microbiotheria
2142:
2137:
2132:
2129:
2128:
2125:
2122:
2119:
2116:
2111:
2106:
2101:
2098:
2097:
2094:
2091:
2088:
2085:
2080:
2075:
2070:
2067:
2066:
2063:
2060:
2057:
2054:
2049:
2044:
2039:
2036:
2035:
2032:
2029:
2026:
2023:
2018:
2013:
2008:
2002:
2001:
1996:
1991:
1986:
1978:
1972:
1967:
1962:
1771:
1768:
1765:
1764:
1761:
1758:
1754:
1753:
1750:
1747:
1743:
1742:
1739:
1736:
1732:
1731:
1728:
1725:
1721:
1720:
1717:
1714:
1710:
1709:
1706:
1703:
1699:
1698:
1695:
1692:
1688:
1687:
1684:
1681:
1675:THAP3 protein
1628:
1625:
1623:
1620:
1581:
1578:
1553:
1550:
1548:
1545:
1515:region and an
1501:The predicted
1485:
1482:
1479:
1478:
1475:
1472:
1469:
1465:
1464:
1461:
1458:
1455:
1451:
1450:
1447:
1444:
1441:
1437:
1436:
1433:
1430:
1427:
1423:
1422:
1419:
1416:
1413:
1409:
1408:
1405:
1402:
1399:
1395:
1394:
1391:
1388:
1385:
1381:
1380:
1377:
1374:
1371:
1367:
1366:
1363:
1360:
1357:
1332:
1329:
1297:of 10.26. The
1260:
1257:
1254:
1253:
1250:
1247:
1243:
1242:
1239:
1236:
1232:
1231:
1228:
1225:
1221:
1220:
1217:
1214:
1210:
1209:
1206:
1203:
1199:
1198:
1195:
1192:
1188:
1187:
1184:
1181:
1177:
1176:
1173:
1170:
1166:
1165:
1160:
1157:
1125:
1122:
1013:
1010:
963:
960:
878:THAP3 protein.
866:
865:
862:
861:
856:
846:
845:
839:
838:
835:
834:
832:
830:
823:
822:
815:
808:
804:
803:
800:
799:
785:
784:
778:
775:
774:
756:
755:
749:
745:
744:
741:
740:
726:
725:
719:
716:
715:
697:
696:
670:
666:
665:
662:
661:
653:
652:
646:
643:
642:
634:
633:
627:
621:
620:
617:
616:
608:
607:
601:
598:
597:
589:
588:
582:
576:
575:
572:
571:
563:
562:
556:
553:
552:
544:
543:
537:
531:
530:
525:
520:
516:
515:
505:
504:
501:
500:
497:
496:
493:
492:
485:
479:
478:
475:
474:
466:
465:
462:
461:
459:
458:
454:
450:
446:
442:
438:
434:
430:
426:
422:
418:
415:
414:
403:
400:
399:
397:
396:
392:
388:
384:
380:
376:
372:
368:
364:
360:
356:
353:
352:
340:
339:
331:
320:
314:
313:
310:RNA expression
302:
301:
298:
297:
289:
285:
284:
276:
273:
268:
262:
261:
252:
245:
239:
235:
234:
229:
223:
222:
214:
213:
201:
200:
197:
196:
188:
184:
183:
175:
172:
167:
161:
160:
151:
144:
138:
134:
133:
126:
120:
119:
111:
110:
98:
97:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
4909:
4898:
4895:
4894:
4892:
4878:
4874:
4869:
4864:
4860:
4856:
4852:
4848:
4844:
4837:
4835:
4831:
4820:
4816:
4810:
4807:
4796:
4792:
4786:
4784:
4780:
4769:
4768:www.ebi.ac.uk
4765:
4759:
4756:
4745:
4741:
4735:
4732:
4727:
4723:
4717:
4714:
4709:
4705:
4699:
4696:
4691:
4687:
4681:
4678:
4673:
4669:
4663:
4660:
4655:
4651:
4645:
4642:
4637:
4633:
4627:
4624:
4619:
4615:
4609:
4606:
4601:
4597:
4591:
4588:
4583:
4579:
4573:
4570:
4565:
4561:
4555:
4552:
4547:
4543:
4537:
4534:
4529:
4525:
4519:
4516:
4511:
4507:
4501:
4498:
4493:
4489:
4483:
4480:
4475:
4471:
4465:
4462:
4457:
4453:
4447:
4444:
4439:
4435:
4429:
4426:
4421:
4417:
4411:
4408:
4403:
4399:
4393:
4390:
4379:
4378:www.ebi.ac.uk
4375:
4369:
4366:
4361:
4357:
4352:
4347:
4343:
4339:
4335:
4331:
4327:
4320:
4317:
4306:
4302:
4296:
4293:
4288:
4284:
4279:
4274:
4270:
4266:
4262:
4258:
4254:
4247:
4244:
4239:
4235:
4229:
4226:
4221:
4217:
4211:
4208:
4203:
4199:
4193:
4190:
4185:
4181:
4175:
4172:
4167:
4163:
4157:
4154:
4149:
4145:
4139:
4136:
4131:
4127:
4121:
4118:
4113:
4109:
4104:
4099:
4094:
4089:
4085:
4081:
4077:
4070:
4067:
4062:
4058:
4053:
4048:
4044:
4040:
4036:
4032:
4028:
4021:
4018:
4007:
4003:
3997:
3994:
3989:
3985:
3980:
3975:
3970:
3965:
3961:
3957:
3953:
3946:
3944:
3940:
3935:
3931:
3927:
3923:
3919:
3915:
3908:
3906:
3902:
3898:
3892:
3890:
3888:
3884:
3879:
3875:
3870:
3865:
3861:
3857:
3853:
3849:
3845:
3838:
3835:
3830:
3826:
3820:
3817:
3812:
3808:
3802:
3799:
3794:
3790:
3784:
3781:
3776:
3772:
3766:
3763:
3758:
3754:
3748:
3745:
3740:
3736:
3730:
3727:
3722:
3718:
3712:
3709:
3704:
3700:
3694:
3691:
3687:
3681:
3678:
3673:
3669:
3664:
3659:
3654:
3649:
3645:
3641:
3637:
3633:
3629:
3622:
3620:
3616:
3611:
3605:
3602:
3597:
3593:
3587:
3584:
3579:
3573:
3570:
3565:
3559:
3556:
3551:
3545:
3542:
3537:
3533:
3527:
3524:
3519:
3515:
3509:
3506:
3501:
3495:
3492:
3481:
3477:
3471:
3469:
3467:
3465:
3463:
3461:
3459:
3457:
3455:
3453:
3451:
3447:
3442:
3438:
3433:
3428:
3424:
3420:
3416:
3412:
3408:
3404:
3400:
3393:
3390:
3385:
3381:
3376:
3371:
3366:
3361:
3357:
3353:
3349:
3342:
3340:
3336:
3325:
3321:
3315:
3313:
3309:
3298:
3294:
3288:
3286:
3282:
3277:
3273:
3268:
3263:
3259:
3255:
3251:
3247:
3243:
3236:
3234:
3230:
3226:. 2022-04-22.
3225:
3219:
3216:
3211:
3207:
3203:
3199:
3195:
3191:
3183:
3180:
3169:
3165:
3159:
3157:
3155:
3153:
3151:
3149:
3147:
3145:
3143:
3141:
3139:
3137:
3133:
3128:
3124:
3119:
3114:
3110:
3106:
3102:
3098:
3094:
3087:
3085:
3081:
3076:
3072:
3067:
3062:
3058:
3054:
3050:
3046:
3042:
3038:
3034:
3027:
3025:
3021:
3016:
3012:
3006:
3003:
2998:
2994:
2988:
2985:
2981:
2977:
2972:
2970:
2968:
2964:
2960:
2956:
2951:
2949:
2947:
2943:
2936:
2934:
2932:
2928:
2924:
2920:
2916:
2912:
2908:
2904:
2900:
2892:
2885:
2883:
2880:
2878:
2875:
2873:
2870:
2869:
2865:
2863:
2860:
2858:
2855:
2853:
2852:
2848:
2846:
2843:
2841:
2838:
2836:
2833:
2832:
2828:
2826:
2823:
2821:
2818:
2816:
2815:
2811:
2809:
2806:
2804:
2801:
2799:
2798:
2794:
2792:
2789:
2787:
2784:
2782:
2781:
2777:
2775:
2771:
2768:
2766:
2763:
2761:
2760:
2756:
2754:
2750:
2747:
2745:
2742:
2740:
2739:
2735:
2733:
2730:
2728:
2725:
2723:
2722:
2718:
2716:
2713:
2711:
2708:
2706:
2703:
2702:
2699:
2696:
2694:
2691:
2689:Protein Name
2688:
2685:
2684:
2680:
2675:
2673:
2669:
2665:
2661:
2657:
2653:
2649:
2648:
2640:
2638:
2636:
2635:immune system
2632:
2629:
2628:
2623:
2619:
2618:
2610:
2603:
2600:
2597:
2594:
2592:
2589:
2587:
2584:
2582:
2579:
2577:
2576:
2572:
2569:
2566:
2563:
2561:
2558:
2556:
2553:
2551:
2548:
2546:
2545:
2541:
2538:
2535:
2532:
2530:
2527:
2525:
2522:
2520:
2517:
2515:
2512:
2511:
2507:
2504:
2501:
2498:
2496:
2495:Cypriniformes
2493:
2491:
2488:
2486:
2483:
2481:
2480:
2476:
2473:
2470:
2467:
2465:
2462:
2460:
2457:
2455:
2452:
2450:
2449:
2445:
2442:
2439:
2436:
2434:
2433:Salmoniformes
2431:
2429:
2426:
2424:
2421:
2419:
2418:
2414:
2411:
2408:
2405:
2403:
2402:Gymnotiformes
2400:
2398:
2395:
2393:
2390:
2388:
2385:
2384:
2380:
2377:
2374:
2371:
2369:
2366:
2364:
2361:
2359:
2356:
2354:
2353:
2349:
2346:
2343:
2340:
2338:
2335:
2333:
2330:
2328:
2325:
2323:
2320:
2319:
2315:
2312:
2309:
2306:
2304:
2301:
2299:
2296:
2294:
2291:
2289:
2288:
2284:
2281:
2278:
2275:
2273:
2270:
2268:
2265:
2263:
2260:
2258:
2257:
2253:
2250:
2247:
2244:
2242:
2239:
2237:
2234:
2232:
2229:
2227:
2226:
2222:
2219:
2216:
2213:
2211:
2208:
2206:
2203:
2201:
2198:
2196:
2193:
2192:
2188:
2185:
2182:
2179:
2177:
2176:Diprotodontia
2174:
2172:
2169:
2167:
2164:
2162:
2161:
2157:
2154:
2151:
2148:
2146:
2143:
2141:
2138:
2136:
2133:
2131:
2130:
2126:
2123:
2120:
2117:
2115:
2112:
2110:
2107:
2105:
2102:
2100:
2099:
2095:
2092:
2089:
2086:
2084:
2081:
2079:
2078:Big brown bat
2076:
2074:
2071:
2069:
2068:
2064:
2061:
2058:
2055:
2053:
2050:
2048:
2045:
2043:
2040:
2038:
2037:
2033:
2030:
2027:
2024:
2022:
2019:
2017:
2014:
2012:
2009:
2007:
2004:
2003:
2000:
1997:
1995:
1992:
1990:
1987:
1985:
1984:
1979:
1977:
1973:
1971:
1968:
1966:
1963:
1961:
1957:
1956:
1952:
1949:Orthologs of
1946:
1944:
1943:
1938:
1936:
1931:
1927:
1923:
1918:
1916:
1912:
1908:
1904:
1900:
1896:
1892:
1888:
1884:
1880:
1879:
1874:
1870:
1866:
1862:
1858:
1854:
1853:invertebrates
1850:
1846:
1842:
1838:
1834:
1830:
1826:
1822:
1818:
1814:
1810:
1806:
1802:
1801:
1796:
1788:
1784:
1781:
1776:
1769:
1762:
1759:
1756:
1755:
1751:
1748:
1745:
1744:
1740:
1737:
1734:
1733:
1729:
1726:
1723:
1722:
1718:
1715:
1712:
1711:
1707:
1704:
1701:
1700:
1696:
1693:
1690:
1689:
1685:
1682:
1680:Protein Name
1679:
1678:
1674:
1668:
1666:
1665:
1660:
1656:
1652:
1648:
1644:
1640:
1636:
1635:
1626:
1621:
1619:
1617:
1616:glycosylation
1613:
1609:
1605:
1601:
1597:
1593:
1589:
1588:
1579:
1577:
1575:
1572:
1571:
1566:
1562:
1558:
1551:
1546:
1544:
1542:
1538:
1534:
1530:
1526:
1522:
1518:
1514:
1510:
1506:
1505:
1495:
1492:Schematic of
1490:
1483:
1476:
1473:
1470:
1467:
1466:
1462:
1459:
1456:
1453:
1452:
1448:
1445:
1442:
1439:
1438:
1434:
1431:
1428:
1425:
1424:
1420:
1417:
1414:
1411:
1410:
1406:
1403:
1400:
1397:
1396:
1392:
1389:
1386:
1383:
1382:
1378:
1375:
1372:
1369:
1368:
1364:
1361:
1358:
1355:
1354:
1350:
1344:
1342:
1338:
1330:
1328:
1326:
1323:are the THAP
1322:
1321:
1316:
1312:
1308:
1304:
1300:
1296:
1292:
1288:
1284:
1280:
1279:
1270:
1265:
1258:
1251:
1248:
1245:
1244:
1240:
1237:
1234:
1233:
1229:
1226:
1223:
1222:
1218:
1215:
1212:
1211:
1207:
1204:
1201:
1200:
1196:
1193:
1190:
1189:
1185:
1182:
1179:
1178:
1174:
1171:
1168:
1167:
1164:
1161:
1158:
1155:
1154:
1150:
1144:
1142:
1138:
1134:
1131:of the THAP3
1130:
1129:Transcription
1123:
1121:
1119:
1116:
1112:
1111:
1106:
1103:
1099:
1098:
1093:
1089:
1085:
1081:
1077:
1073:
1069:
1065:
1064:adrenal gland
1061:
1057:
1053:
1049:
1045:
1041:
1037:
1033:
1029:
1025:
1021:
1020:
1011:
1006:
1001:
997:
995:
991:
987:
983:
979:
975:
971:
970:
961:
959:
957:
953:
951:
946:
942:
938:
937:transcription
934:
930:
926:
922:
919:contains the
918:
914:
910:
906:
902:
898:
897:
892:
888:
884:
877:
872:
860:
855:
851:
847:
844:
840:
833:
831:
828:
824:
820:
816:
813:
809:
805:
798:
796:
792:
786:
782:
779:
773:
771:
767:
763:
757:
753:
750:
746:
739:
737:
733:
727:
723:
720:
714:
712:
708:
704:
698:
694:
690:
686:
682:
678:
674:
671:
669:RefSeq (mRNA)
667:
660:
659:
654:
650:
647:
641:
640:
635:
631:
628:
626:
622:
615:
614:
609:
605:
602:
596:
595:
590:
586:
583:
581:
577:
570:
569:
564:
560:
557:
551:
550:
545:
541:
538:
536:
532:
529:
526:
524:
521:
517:
514:
510:
506:
494:
489:
486:
484:
480:
472:
467:
456:
452:
448:
444:
440:
436:
432:
428:
424:
420:
419:
416:
412:
407:
404:
394:
390:
386:
382:
378:
374:
370:
366:
362:
359:apex of heart
358:
357:
354:
350:
345:
342:
341:
338:
336:
332:
330:
329:
325:
324:
321:
319:
315:
311:
307:
303:
295:
290:
286:
282:
277:
267:
263:
256:
249:
243:
236:
228:
224:
220:
215:
211:
206:
202:
194:
189:
185:
181:
176:
166:
162:
155:
148:
142:
135:
131:
125:
121:
117:
112:
108:
103:
99:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
4853:(2): 32–38.
4850:
4846:
4822:. Retrieved
4818:
4809:
4798:. Retrieved
4794:
4771:. Retrieved
4767:
4758:
4747:. Retrieved
4743:
4734:
4725:
4716:
4707:
4698:
4689:
4680:
4671:
4662:
4653:
4644:
4635:
4626:
4617:
4608:
4599:
4590:
4581:
4572:
4563:
4554:
4545:
4536:
4527:
4518:
4509:
4500:
4491:
4482:
4473:
4464:
4455:
4446:
4437:
4428:
4419:
4410:
4401:
4392:
4381:. Retrieved
4377:
4368:
4333:
4329:
4319:
4308:. Retrieved
4304:
4295:
4260:
4256:
4246:
4237:
4228:
4219:
4210:
4201:
4192:
4183:
4174:
4165:
4156:
4147:
4138:
4129:
4120:
4083:
4079:
4069:
4037:(2): 76–85.
4034:
4030:
4020:
4009:. Retrieved
4006:psort.hgc.jp
4005:
3996:
3959:
3955:
3917:
3913:
3896:
3851:
3847:
3837:
3828:
3819:
3810:
3801:
3792:
3783:
3774:
3765:
3756:
3747:
3738:
3729:
3720:
3711:
3702:
3693:
3685:
3680:
3635:
3631:
3604:
3595:
3586:
3572:
3558:
3544:
3535:
3526:
3517:
3508:
3494:
3483:. Retrieved
3479:
3406:
3402:
3392:
3355:
3351:
3327:. Retrieved
3323:
3300:. Retrieved
3297:www.omim.org
3296:
3249:
3245:
3218:
3196:(2): 66–69.
3193:
3189:
3182:
3171:. Retrieved
3167:
3100:
3096:
3040:
3036:
3014:
3005:
2996:
2987:
2915:bradykinesia
2896:
2697:
2692:
2679:Homo sapiens
2678:
2645:
2644:
2625:
2615:
2614:
2586:Thorny skate
2580:
2549:
2518:
2490:Sumatra barb
2484:
2453:
2422:
2397:Electric eel
2391:
2357:
2326:
2292:
2261:
2230:
2199:
2165:
2134:
2103:
2072:
2041:
2010:
1998:
1993:
1988:
1980:
1951:Homo sapiens
1950:
1940:
1933:
1919:
1876:
1807:, including
1798:
1792:
1786:
1782:
1779:
1673:Homo sapiens
1672:
1671:Paralogs of
1662:
1632:
1630:
1606:involved in
1585:
1583:
1568:
1565:mitochondria
1556:
1555:
1552:Localization
1502:
1500:
1494:Homo sapiens
1493:
1390:NP_612359.2
1349:Homo sapiens
1348:
1347:Isoforms of
1334:
1318:
1301:sequence is
1276:
1274:
1269:Homo sapiens
1268:
1186:NM_138350.4
1162:
1149:Homo sapiens
1148:
1127:
1108:
1095:
1017:
1015:
1005:Homo sapiens
1004:
986:chromosome 1
967:
965:
948:
903:. The THAP3
896:Homo sapiens
894:
886:
882:
881:
876:Homo sapiens
875:
791:NP_001139401
788:
766:NP_001182682
762:NP_001182681
759:
732:NM_001145929
729:
711:NM_001394500
707:NM_001394499
703:NM_001394498
700:
693:NM_001394497
689:NM_001394496
681:NM_001195753
677:NM_001195752
656:
637:
611:
592:
566:
547:
527:
522:
421:otic vesicle
395:frontal pole
333:
326:
292:152,073,454
279:152,067,096
53:External IDs
2866:Functional
2849:Functional
2829:Functional
2812:Functional
2795:Functional
2778:Functional
2757:Functional
2736:Functional
2719:Functional
2672:translation
2670:during its
2524:Whale shark
2387:Bony Fishes
2368:Gymnophiona
2337:Gymnophiona
1970:Common Name
1913:(frogs) or
1821:bony fishes
1541:amino acids
1537:alpha helix
1533:amino acids
1531:. It spans
1517:alpha helix
1511:contains a
1365:Encoded by
1291:kilodaltons
911:associated
383:granulocyte
271:4|4 E2
31:Identifiers
4824:2022-12-08
4800:2022-12-16
4773:2022-12-16
4749:2022-12-16
4383:2022-12-08
4310:2022-12-08
4263:(1): 539.
4011:2022-12-16
3962:: 831740.
3485:2022-12-08
3329:2022-12-16
3302:2022-12-15
3173:2022-12-08
2982:, May 2017
2961:, May 2017
2937:References
2647:H. sapiens
2627:H. sapiens
2620:THAP3 has
2617:H. sapiens
2591:Rajiformes
2459:Baby whale
2322:Amphibians
2303:Testudines
2272:Testudines
2241:Testudines
2210:Testudines
2109:Blue whale
2083:Chiroptera
1983:Divergence
1974:Taxonomic
1958:Taxonomic
1942:H. sapiens
1935:H. sapiens
1903:amphibians
1887:crocodilia
1883:testudines
1878:H. sapiens
1817:amphibians
1800:H. sapiens
1795:orthlologs
1787:H. sapiens
1664:H. sapiens
1634:H. sapiens
1590:the THAP3
1587:H. sapiens
1570:H. sapiens
1547:Regulation
1535:4-82. The
1525:N-terminus
1504:H. sapiens
1477:Variant 8
1463:Variant 7
1449:Variant 6
1435:Variant 5
1421:Variant 4
1407:Variant 3
1393:Variant 2
1379:Variant 1
1320:H. sapiens
1303:isoleucine
1299:amino acid
1278:H. sapiens
1110:H. sapiens
1097:H. sapiens
1080:expression
1040:expression
1032:expression
1019:H. sapiens
1012:Expression
990:base pairs
980:-encoding
969:H. sapiens
950:H. sapiens
433:knee joint
337:(ortholog)
191:6,635,586
178:6,624,868
74:HomoloGene
4740:"UniProt"
2611:Evolution
2052:Carnivora
1926:orthologs
1922:organisms
1907:orthologs
1895:orthologs
1873:orthologs
1829:orthologs
1770:Orthologs
1683:E-Value!
1484:Structure
1309:rich and
1078:, though
945:expressed
909:apoptosis
893:that, in
795:NP_780361
770:NP_612359
736:NM_175152
685:NM_138350
513:Orthologs
82:GeneCards
4891:Category
4877:24868378
4360:35932227
4287:21988835
4112:30836974
4086:(1): 4.
4061:24388790
3988:35252351
3934:10600390
3878:26069263
3441:25970244
3384:24309898
3276:20010837
3210:12575992
3127:34791371
3075:34265844
2978:–
2957:–
2931:dystonia
2919:rigidity
2686:Process
2652:proteins
2195:Reptiles
2021:Rodentia
1981:Date of
1891:squamata
1869:reptiles
1841:protists
1833:bacteria
1813:reptiles
1659:paralogs
1651:proteins
1643:proteins
1627:Paralogs
1604:proteins
1521:globular
1513:globular
1356:Isoform
1341:isoforms
1331:Isoforms
1311:arginine
1307:tyrosine
1289:of 26.9
1156:Variant
1107:than in
1090:. THAP3
1060:prostate
1022:, THAP3
921:Thanatos
915:3. This
843:Wikidata
4868:4027667
4351:9400175
4278:3261699
4103:6402169
4052:3954851
3979:8892267
3869:4595897
3672:1549558
3640:Bibcode
3432:4529404
3411:Bibcode
3375:3916642
3267:2933787
3118:8728224
3066:8371605
3045:Bibcode
2980:Ensembl
2959:Ensembl
2911:tremors
2658:, like
2622:evolved
2114:Cetacea
2006:Mammals
1930:rodents
1915:urodela
1901:within
1845:archaea
1809:mammals
1805:classes
1783:sapiens
1667:THAP3.
1639:protein
1592:protein
1561:nucleus
1315:domains
1283:protein
1259:Protein
1084:kidneys
1082:in the
1052:ovaries
1048:abdomen
1036:kidneys
1028:tissues
978:protein
956:kidneys
933:domains
917:protein
913:protein
905:protein
891:protein
889:) is a
625:UniProt
580:Ensembl
519:Species
312:pattern
170:1p36.31
70:1917126
38:Aliases
4875:
4865:
4358:
4348:
4285:
4275:
4110:
4100:
4059:
4049:
3986:
3976:
3932:
3876:
3866:
3670:
3660:
3439:
3429:
3403:Nature
3382:
3372:
3274:
3264:
3208:
3125:
3115:
3073:
3063:
3037:Nature
2857:DNAJB6
2820:TARDBP
2803:POLR2A
1953:THAP3
1861:orders
1849:plants
1823:, and
1763:32.99
1757:THAP9
1752:31.96
1746:THAP8
1741:33.33
1735:THAP7
1730:34.44
1724:THAP6
1719:31.96
1713:THAP5
1708:45.24
1702:THAP2
1697:48.00
1691:THAP1
1655:domain
1637:THAP3
1529:domain
1519:. The
1507:THAP3
1351:THAP3
1325:domain
1293:and a
1281:THAP3
1118:tissue
1115:kidney
1113:adult
1105:tissue
1100:fetal
1088:organs
1074:, and
1068:spleen
1056:testes
1044:organs
1030:, and
972:THAP3
927:and a
925:domain
829:search
827:PubMed
658:Q8BJ25
639:Q8WTV1
535:Entrez
483:BioGPS
62:612532
3663:48584
2840:LSAMP
2744:HCF1C
2727:FGFR3
2604:54.1
2601:40.2
2573:53.0
2570:39.0
2542:53.4
2539:39.0
2508:48.1
2505:34.0
2477:46.3
2474:33.5
2446:47.7
2443:32.9
2415:41.3
2412:31.9
2381:57.8
2378:44.2
2350:56.8
2347:41.2
2316:60.9
2313:49.0
2285:61.4
2282:48.9
2254:58.1
2251:48.9
2223:47.2
2220:36.9
2189:76.4
2186:65.7
2171:Koala
2158:74.5
2155:64.6
2127:82.9
2124:77.5
2096:69.6
2093:65.0
2065:65.8
2062:59.5
2031:29.9
1976:Order
1960:Class
1911:anura
1899:apoda
1865:class
1857:birds
1855:, or
1837:fungi
1760:2×10
1749:8×10
1738:1×10
1727:6×10
1716:4×10
1705:6×10
1694:8×10
1574:cells
1557:THAP3
1249:1120
1238:1123
1227:2047
1216:2050
1205:1262
1194:1361
1183:2071
1172:1358
1102:brain
1076:colon
1072:liver
994:exons
976:is a
887:THAP3
568:69876
549:90326
528:Mouse
523:Human
371:gonad
335:Mouse
328:Human
275:Start
210:Mouse
174:Start
107:Human
86:THAP3
78:18413
45:THAP3
22:THAP3
4873:PMID
4356:PMID
4283:PMID
4108:PMID
4057:PMID
3984:PMID
3930:PMID
3874:PMID
3668:PMID
3437:PMID
3380:PMID
3272:PMID
3206:PMID
3123:PMID
3071:PMID
2929:and
2877:BAG6
2786:PKN1
2710:CHAT
2662:and
2595:464
2564:464
2533:464
2499:431
2468:431
2437:431
2406:431
2372:353
2341:353
2307:319
2276:319
2245:319
2214:319
2180:160
2149:160
1780:Homo
1631:The
1614:and
1584:The
1471:147
1457:148
1443:167
1429:168
1415:236
1401:239
1387:175
1373:238
1305:and
1275:The
1137:mRNA
1133:gene
1124:mRNA
1092:mRNA
1024:gene
982:gene
974:gene
966:The
962:Gene
939:and
901:gene
318:Bgee
266:Band
227:Chr.
165:Band
124:Chr.
58:OMIM
4863:PMC
4855:doi
4346:PMC
4338:doi
4273:PMC
4265:doi
4098:PMC
4088:doi
4047:PMC
4039:doi
3974:PMC
3964:doi
3922:doi
3918:294
3864:PMC
3856:doi
3658:PMC
3648:doi
3427:PMC
3419:doi
3407:521
3370:PMC
3360:doi
3262:PMC
3254:doi
3198:doi
3113:PMC
3105:doi
3061:PMC
3053:doi
3041:596
2765:OGT
2118:94
2087:94
2056:94
2034:36
2025:87
1909:in
1897:in
1875:to
1831:in
1797:of
1661:of
1567:of
1563:or
1317:of
1016:In
996:.
947:in
491:n/a
425:lip
288:End
187:End
90:OMA
66:MGI
4893::
4871:.
4861:.
4849:.
4845:.
4833:^
4817:.
4793:.
4782:^
4766:.
4742:.
4724:.
4706:.
4688:.
4670:.
4652:.
4634:.
4616:.
4598:.
4580:.
4562:.
4544:.
4526:.
4508:.
4490:.
4472:.
4454:.
4436:.
4418:.
4400:.
4376:.
4354:.
4344:.
4334:39
4332:.
4328:.
4303:.
4281:.
4271:.
4259:.
4255:.
4236:.
4218:.
4200:.
4182:.
4164:.
4146:.
4128:.
4106:.
4096:.
4084:19
4082:.
4078:.
4055:.
4045:.
4035:35
4033:.
4029:.
4004:.
3982:.
3972:.
3958:.
3954:.
3942:^
3928:.
3916:.
3904:^
3886:^
3872:.
3862:.
3852:31
3850:.
3846:.
3827:.
3809:.
3791:.
3773:.
3755:.
3737:.
3719:.
3701:.
3666:.
3656:.
3646:.
3636:89
3634:.
3630:.
3618:^
3594:.
3534:.
3516:.
3478:.
3449:^
3435:.
3425:.
3417:.
3405:.
3401:.
3378:.
3368:.
3356:13
3354:.
3350:.
3338:^
3322:.
3311:^
3295:.
3284:^
3270:.
3260:.
3250:17
3248:.
3244:.
3232:^
3204:.
3194:28
3192:.
3166:.
3135:^
3121:.
3111:.
3101:50
3099:.
3095:.
3083:^
3069:.
3059:.
3051:.
3039:.
3035:.
3023:^
3013:.
2995:.
2966:^
2945:^
2925:,
2921:,
2917:,
2913:,
2772:-
2751:-
2674:.
2637:.
1871:,
1851:,
1847:,
1843:,
1839:,
1835:,
1819:,
1815:,
1811:,
1576:.
1468:8
1454:7
1440:6
1426:5
1412:4
1398:3
1384:2
1370:1
1343:.
1295:pI
1246:8
1235:7
1224:6
1213:5
1202:4
1191:3
1180:2
1169:1
1120:.
1070:,
1066:,
1062:,
1058:,
1054:,
958:.
294:bp
281:bp
193:bp
180:bp
88:;
84::
80:;
76::
72:;
68::
64:;
60::
4879:.
4857::
4851:3
4827:.
4803:.
4776:.
4752:.
4728:.
4710:.
4692:.
4674:.
4656:.
4638:.
4620:.
4602:.
4584:.
4566:.
4548:.
4530:.
4512:.
4494:.
4476:.
4458:.
4440:.
4422:.
4404:.
4386:.
4362:.
4340::
4313:.
4289:.
4267::
4261:7
4240:.
4222:.
4204:.
4186:.
4168:.
4150:.
4132:.
4114:.
4090::
4063:.
4041::
4014:.
3990:.
3966::
3960:9
3936:.
3924::
3880:.
3858::
3831:.
3813:.
3795:.
3777:.
3759:.
3741:.
3723:.
3705:.
3674:.
3650::
3642::
3488:.
3443:.
3421::
3413::
3386:.
3362::
3332:.
3305:.
3278:.
3256::
3212:.
3200::
3176:.
3129:.
3107::
3077:.
3055::
3047::
3017:.
2999:.
1937:.
952:,
885:(
212:)
109:)
92::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
