Knowledge (XXG)

TIPIN

Source 📝

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Gotter AL (Aug 2003). "Tipin, a novel timeless-interacting protein, is developmentally co-expressed with timeless and disrupts its self-association".
1617: 1593: 1612: 1162: 1144: 241: 996: 1003: 218: 1256: 1217:"Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint" 1131: 1110: 140: 115: 1127: 1106: 1412:"Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function" 57: 1326:"The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement" 1272:"The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement" 1078: 254: 153: 1586: 247: 146: 781: 65: 762: 1082: 1579: 129: 1423: 44: 975: 971: 967: 942: 916: 912: 908: 883: 879: 875: 871: 861: 857: 853: 845: 1465:"Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing" 1324:
Unsal-Kaçmaz K, Chastain PD, Qu PP, Minoo P, Cordeiro-Stone M, Sancar A, Kaufmann WK (Apr 2007).
1270:
Unsal-Kaçmaz K, Chastain PD, Qu PP, Minoo P, Cordeiro-Stone M, Sancar A, Kaufmann WK (Apr 2007).
89: 979: 946: 904: 849: 1369:"Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors" 1529: 1494: 1451: 1398: 1355: 1301: 1238: 1197: 37: 1563: 1519: 1484: 1476: 1441: 1431: 1388: 1380: 1345: 1337: 1291: 1283: 1228: 1189: 334: 265: 209: 164: 492: 85: 309: 1427: 1489: 1464: 1446: 1411: 1393: 1368: 1350: 1325: 1296: 1271: 1193: 651: 646: 641: 636: 631: 626: 621: 616: 611: 606: 601: 596: 591: 575: 570: 565: 560: 555: 539: 534: 1606: 1559: 521: 69: 327: 106: 1480: 93: 1167:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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Proceedings of the National Academy of Sciences of the United States of America
410: 1384: 226: 123: 73: 1508:"Normalization and subtraction: two approaches to facilitate gene discovery" 1436: 681: 470: 348: 293: 280: 192: 179: 81: 1498: 1463:
Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (Sep 2000).
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positive regulation of cell population proliferation
960: 935: 897: 844: 1123: 1121: 1119: 1102: 1100: 1098: 1257:"Entrez Gene: TIPIN TIMELESS interacting protein" 264: 163: 617:regulation of nuclear cell cycle DNA replication 597:mitotic intra-S DNA damage checkpoint signaling 16:Protein-coding gene in the species Homo sapiens 1128:GRCm38: Ensembl release 89: ENSMUSG00000032397 1587: 8: 1506:Bonaldo MF, Lennon G, Soares MB (Sep 1996). 1367:Gotter AL, Suppa C, Emanuel BS (Feb 2007). 1107:GRCh38: Ensembl release 89: ENSG00000075131 1594: 1580: 841: 677: 517: 305: 204: 101: 1523: 1488: 1445: 1435: 1392: 1349: 1295: 1232: 421:fetal liver hematopoietic progenitor cell 1215:Yoshizawa-Sugata N, Masai H (Jan 2007). 602:cellular response to DNA damage stimulus 556:intracellular membrane-bounded organelle 1094: 18: 269: 230: 225: 168: 127: 122: 7: 1544: 1542: 612:DNA replication checkpoint signaling 1221:The Journal of Biological Chemistry 576:replication fork protection complex 1566:. You can help Knowledge (XXG) by 957: 932: 894: 817: 798: 772: 753: 727: 708: 487: 405: 343: 322: 14: 1062:that in humans is encoded by the 1546: 1410:Chou DM, Elledge SJ (Nov 2006). 491: 253: 246: 240: 217: 152: 145: 139: 114: 642:DNA damage checkpoint signaling 1618:Human chromosome 15 gene stubs 1330:Molecular and Cellular Biology 1276:Molecular and Cellular Biology 502:More reference expression data 471:More reference expression data 48:, TIMELESS interacting protein 1: 1194:10.1016/S0022-2836(03)00633-8 238: 137: 1613:Genes on human chromosome 15 1373:Journal of Molecular Biology 1182:Journal of Molecular Biology 1056:TIMELESS-interacting protein 1481:10.1093/embo-reports/kvd058 637:replication fork protection 592:cell cycle phase transition 1634: 1541: 425:medial ganglionic eminence 1385:10.1016/j.jmb.2006.10.097 1163:"Mouse PubMed Reference:" 1145:"Human PubMed Reference:" 1042: 1037: 1033: 1026: 1010: 991: 964: 939: 928: 901: 868: 837: 824: 820: 805: 801: 792: 779: 775: 760: 756: 747: 734: 730: 715: 711: 702: 687: 680: 676: 660: 520: 516: 499: 490: 481: 468: 417: 408: 355: 346: 316: 308: 304: 287: 274: 237: 216: 207: 203: 186: 173: 136: 113: 104: 100: 55: 52: 42: 35: 30: 26: 21: 1077:TIPIN has been shown to 997:Chr 15: 66.34 – 66.39 Mb 1437:10.1073/pnas.0609251103 1004:Chr 9: 64.19 – 64.21 Mb 632:replication fork arrest 1234:10.1074/jbc.M605596200 1083:Replication protein A1 429:mandibular prominence 130:Chromosome 15 (human) 1342:10.1128/MCB.02190-06 1288:10.1128/MCB.02190-06 445:maxillary prominence 232:Chromosome 9 (mouse) 1428:2006PNAS..10318143C 391:islet of Langerhans 383:ganglionic eminence 1554:This article on a 1525:10.1101/gr.6.9.791 782:ENSMUSG00000032397 585:Biological process 549:Cellular component 528:Molecular function 271:9 C|9 34.6 cM 1575: 1574: 1053: 1052: 1049: 1048: 1022: 1021: 987: 986: 954: 953: 924: 923: 891: 890: 833: 832: 814: 813: 788: 787: 769: 768: 743: 742: 724: 723: 672: 671: 512: 511: 508: 507: 477: 476: 464: 463: 402: 401: 300: 299: 199: 198: 94:TIPIN - orthologs 1625: 1596: 1589: 1582: 1550: 1543: 1537: 1527: 1502: 1492: 1459: 1449: 1439: 1406: 1396: 1363: 1353: 1310: 1309: 1299: 1267: 1261: 1260: 1253: 1247: 1246: 1236: 1212: 1206: 1205: 1177: 1171: 1170: 1159: 1153: 1152: 1141: 1135: 1125: 1114: 1104: 1035: 1034: 1006: 999: 982: 958: 949: 933: 929:RefSeq (protein) 919: 895: 886: 842: 818: 799: 773: 754: 728: 709: 678: 518: 504: 495: 488: 473: 457:ventricular zone 453:primitive streak 413: 411:Top expressed in 406: 387:ventricular zone 371:secondary oocyte 351: 349:Top expressed in 344: 323: 306: 296: 283: 272: 257: 250: 244: 233: 221: 205: 195: 182: 171: 156: 149: 143: 132: 118: 102: 96: 47: 40: 19: 1633: 1632: 1628: 1627: 1626: 1624: 1623: 1622: 1603: 1602: 1601: 1600: 1540: 1512:Genome Research 1505: 1462: 1422:(48): 18143–7. 1409: 1366: 1323: 1319: 1317:Further reading 1314: 1313: 1269: 1268: 1264: 1255: 1254: 1250: 1214: 1213: 1209: 1179: 1178: 1174: 1161: 1160: 1156: 1143: 1142: 1138: 1126: 1117: 1105: 1096: 1091: 1075: 1044:View/Edit Mouse 1039:View/Edit Human 1002: 995: 992:Location (UCSC) 978: 974: 970: 966: 945: 941: 915: 911: 907: 903: 882: 878: 874: 870: 864: 860: 856: 852: 848: 763:ENSG00000075131 656: 652:DNA replication 580: 544: 535:protein binding 500: 469: 460: 455: 451: 447: 443: 439: 435: 431: 427: 423: 409: 398: 393: 389: 385: 381: 377: 373: 369: 367:Achilles tendon 365: 361: 347: 291: 278: 270: 260: 259: 258: 251: 231: 208:Gene location ( 190: 177: 169: 159: 158: 157: 150: 128: 105:Gene location ( 56: 43: 36: 17: 12: 11: 5: 1631: 1629: 1621: 1620: 1615: 1605: 1604: 1599: 1598: 1591: 1584: 1576: 1573: 1572: 1551: 1539: 1538: 1518:(9): 791–806. 1503: 1460: 1407: 1364: 1336:(8): 3131–42. 1320: 1318: 1315: 1312: 1311: 1282:(8): 3131–42. 1262: 1248: 1227:(4): 2729–40. 1207: 1172: 1154: 1136: 1115: 1093: 1092: 1090: 1087: 1074: 1071: 1051: 1050: 1047: 1046: 1041: 1031: 1030: 1024: 1023: 1020: 1019: 1017: 1015: 1008: 1007: 1000: 993: 989: 988: 985: 984: 962: 961: 955: 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151: 144: 138: 134: 133: 126: 120: 119: 111: 110: 98: 97: 54: 50: 49: 41: 33: 32: 28: 27: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 1630: 1619: 1616: 1614: 1611: 1610: 1608: 1597: 1592: 1590: 1585: 1583: 1578: 1577: 1571: 1569: 1565: 1561: 1560:chromosome 15 1557: 1552: 1549: 1545: 1535: 1531: 1526: 1521: 1517: 1513: 1509: 1504: 1500: 1496: 1491: 1486: 1482: 1478: 1475:(3): 287–92. 1474: 1470: 1466: 1461: 1457: 1453: 1448: 1443: 1438: 1433: 1429: 1425: 1421: 1417: 1413: 1408: 1404: 1400: 1395: 1390: 1386: 1382: 1378: 1374: 1370: 1365: 1361: 1357: 1352: 1347: 1343: 1339: 1335: 1331: 1327: 1322: 1321: 1316: 1307: 1303: 1298: 1293: 1289: 1285: 1281: 1277: 1273: 1266: 1263: 1258: 1252: 1249: 1244: 1240: 1235: 1230: 1226: 1222: 1218: 1211: 1208: 1203: 1199: 1195: 1191: 1188:(1): 167–76. 1187: 1183: 1176: 1173: 1168: 1164: 1158: 1155: 1150: 1146: 1140: 1137: 1133: 1129: 1124: 1122: 1120: 1116: 1112: 1108: 1103: 1101: 1099: 1095: 1088: 1086: 1084: 1080: 1072: 1070: 1068: 1065: 1061: 1057: 1045: 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379:left testis 292:64,212,706 279:64,188,863 191:66,386,746 178:66,336,191 31:Identifiers 1607:Categories 1134:, May 2017 1113:, May 2017 1089:References 627:cell cycle 337:(ortholog) 74:HomoloGene 1558:on human 980:NP_079648 947:NP_060328 905:NM_025372 850:NM_017858 682:Orthologs 571:cytoplasm 82:GeneCards 1499:11256614 1456:17116885 1403:17141802 1360:17296725 1306:17296725 1243:17102137 1202:12875843 1130:– 1109:– 1079:interact 1028:Wikidata 661:Sources: 363:testicle 170:15q22.31 1534:8889548 1490:1083732 1447:1654129 1424:Bibcode 1394:4151250 1351:1899931 1297:1899931 1132:Ensembl 1111:Ensembl 1060:protein 794:UniProt 749:Ensembl 688:Species 667:QuickGO 561:nucleus 312:pattern 70:1921571 38:Aliases 1532:  1497:  1487:  1454:  1444:  1401:  1391:  1358:  1348:  1304:  1294:  1241:  1200:  1014:search 1012:PubMed 827:Q91WA1 808:Q9BVW5 704:Entrez 483:BioGPS 449:somite 441:embryo 62:610716 1562:is a 1081:with 1064:TIPIN 1058:is a 737:66131 718:54962 697:Mouse 692:Human 663:Amigo 395:sperm 359:gonad 335:Mouse 328:Human 275:Start 210:Mouse 174:Start 107:Human 86:TIPIN 78:32373 45:TIPIN 22:TIPIN 1564:stub 1556:gene 1530:PMID 1495:PMID 1452:PMID 1399:PMID 1356:PMID 1302:PMID 1239:PMID 1198:PMID 1067:gene 318:Bgee 266:Band 227:Chr. 165:Band 124:Chr. 58:OMIM 1520:doi 1485:PMC 1477:doi 1442:PMC 1432:doi 1420:103 1389:PMC 1381:doi 1377:366 1346:PMC 1338:doi 1292:PMC 1284:doi 1229:doi 1225:282 1190:doi 1186:331 288:End 187:End 90:OMA 66:MGI 1609:: 1528:. 1514:. 1510:. 1493:. 1483:. 1471:. 1467:. 1450:. 1440:. 1430:. 1418:. 1414:. 1397:. 1387:. 1375:. 1371:. 1354:. 1344:. 1334:27 1332:. 1328:. 1300:. 1290:. 1280:27 1278:. 1274:. 1237:. 1223:. 1219:. 1196:. 1184:. 1165:. 1147:. 1118:^ 1097:^ 1085:. 1069:. 665:/ 294:bp 281:bp 193:bp 180:bp 88:; 84:: 80:; 76:: 72:; 68:: 64:; 60:: 1595:e 1588:t 1581:v 1570:. 1536:. 1522:: 1516:6 1501:. 1479:: 1473:1 1458:. 1434:: 1426:: 1405:. 1383:: 1362:. 1340:: 1308:. 1286:: 1259:. 1245:. 1231:: 1204:. 1192:: 1169:. 1151:. 212:) 109:) 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Index

Aliases
TIPIN
OMIM
610716
MGI
1921571
HomoloGene
32373
GeneCards
TIPIN
OMA
TIPIN - orthologs
Human
Chromosome 15 (human)
Chr.
Chromosome 15 (human)
Chromosome 15 (human)
Genomic location for TIPIN
Genomic location for TIPIN
Band
bp
bp
Mouse
Chromosome 9 (mouse)
Chr.
Chromosome 9 (mouse)
Genomic location for TIPIN
Genomic location for TIPIN
Band
bp

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