247:
224:
121:
146:
505:
498:
1775:
1760:
253:
152:
29:
1745:
1803:
1448:
Stifani S, Blaumueller CM, Redhead NJ, Hill RE, Artavanis-Tsakonas S (October 1992). "Human homologs of a
Drosophila Enhancer of split gene product define a novel family of nuclear proteins".
260:
159:
1487:"Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro"
1292:"Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein"
743:
82:
724:
1872:
1848:
1774:
1759:
1724:
1272:
1254:
53:, BCE-1, BCE1, E(spI), ESG, ESG4, GRG4, Grg-4, transducin like enhancer of split 4, TLE family member 4, transcriptional corepressor, E(spl)
1867:
246:
1110:
1103:
223:
1331:
1241:
1220:
1659:
Heimbucher T, Murko C, Bajoghli B, Aghaallaei N, Huber A, Stebegg R, Eberhard D, Fink M, Simeone A, Czerny T (January 2007).
1237:
145:
120:
1744:
1216:
62:
1188:
259:
158:
1841:
1717:
1606:
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (August 2004).
252:
151:
788:
70:
769:
1522:"Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family"
1347:"Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family"
1834:
1710:
1619:
134:
49:
1082:
1078:
1074:
1053:
1049:
1045:
1041:
1037:
1033:
1029:
1025:
1021:
1017:
1013:
1009:
1005:
991:
987:
983:
979:
959:
955:
951:
926:
922:
918:
914:
910:
906:
902:
898:
894:
890:
886:
882:
878:
864:
860:
856:
852:
1473:
94:
1565:"A new Groucho TLE4 protein may regulate the repressive activity of Pax5 in human B lymphocytes"
1396:"A new Groucho TLE4 protein may regulate the repressive activity of Pax5 in human B lymphocytes"
1086:
995:
947:
868:
1690:
1647:
1594:
1551:
1508:
1465:
1425:
1376:
1313:
42:
1818:
1680:
1672:
1637:
1627:
1584:
1576:
1541:
1533:
1498:
1457:
1415:
1407:
1366:
1358:
1303:
504:
339:
270:
214:
169:
547:
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
497:
314:
90:
1623:
1685:
1660:
1589:
1564:
1420:
1395:
1308:
1291:
1642:
1607:
1546:
1521:
1371:
1346:
658:
653:
648:
643:
638:
633:
628:
623:
618:
602:
597:
592:
587:
571:
566:
561:
556:
551:
28:
1861:
1580:
1411:
533:
1477:
1332:"Entrez Gene: TLE4 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)"
1814:
332:
111:
74:
98:
1277:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1259:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1612:
Proceedings of the
National Academy of Sciences of the United States of America
1537:
1362:
415:
1485:
Nagase T, Ishikawa K, Kikuno R, Hirosawa M, Nomura N, Ohara O (October 1999).
231:
128:
78:
1503:
1486:
1632:
688:
475:
353:
298:
285:
197:
184:
86:
1694:
1651:
1598:
1555:
1512:
1429:
1380:
1469:
1317:
1150:
1145:
546:
1676:
1661:"Gbx2 and Otx2 interact with the WD40 domain of Groucho/Tle corepressors"
1134:
833:
814:
1461:
1166:
800:
755:
1118:
710:
567:
DNA-binding transcription factor activity, RNA polymerase II-specific
1802:
1608:"Large-scale characterization of HeLa cell nuclear phosphoproteins"
1563:
Milili M, Gauthier L, Veran J, Mattei MG, Schiff C (August 2002).
1394:
Milili M, Gauthier L, Veran J, Mattei MG, Schiff C (August 2002).
673:
669:
1810:
1192:
1173:
66:
1706:
513:
1702:
1520:
Eberhard D, Jiménez G, Heavey B, Busslinger M (May 2000).
1345:
Eberhard D, Jiménez G, Heavey B, Busslinger M (May 2000).
629:
negative regulation of transcription by RNA polymerase II
322:
1822:
1290:
Miyasaka H, Choudhury BK, Hou EW, Li SS (August 1993).
1783:: A WRPW PEPTIDE BOUND TO THE GROUCHO-TLE WD40 DOMAIN.
1768:: AN EH1 PEPTIDE BOUND TO THE GROUCHO-TLE WD40 DOMAIN.
659:
negative regulation of canonical Wnt signaling pathway
487:
1067:
978:
940:
851:
619:
negative regulation of transcription, DNA-templated
1233:
1231:
1229:
1212:
1210:
1208:
269:
168:
649:cellular response to leukemia inhibitory factor
16:Protein-coding gene in the species Homo sapiens
1238:GRCm38: Ensembl release 89: ENSMUSG00000024642
1842:
1718:
8:
1217:GRCh38: Ensembl release 89: ENSG00000106829
1849:
1835:
1725:
1711:
1703:
975:
848:
684:
624:regulation of transcription, DNA-templated
529:
310:
209:
106:
1684:
1641:
1631:
1588:
1545:
1502:
1419:
1370:
1307:
1740:
1204:
18:
274:
235:
230:
173:
132:
127:
7:
1799:
1797:
434:vestibular membrane of cochlear duct
1753:: WD40 REGION OF HUMAN GROUCHO/TLE1
392:dorsal motor nucleus of vagus nerve
1821:. You can help Knowledge (XXG) by
1309:10.1111/j.1432-1033.1993.tb18151.x
1163:Transducin-like enhancer protein 4
1064:
937:
824:
805:
779:
760:
734:
715:
562:transcription corepressor activity
492:
410:
348:
327:
14:
1169:that in humans is encoded by the
644:beta-catenin-TCF complex assembly
1801:
1773:
1758:
1743:
1581:10.1046/j.1365-2567.2002.01456.x
1412:10.1046/j.1365-2567.2002.01456.x
1296:European Journal of Biochemistry
503:
496:
388:inferior ganglion of vagus nerve
258:
251:
245:
222:
157:
150:
144:
119:
27:
598:transcription regulator complex
1665:Molecular and Cellular Biology
514:More reference expression data
476:More reference expression data
396:Region I of hippocampus proper
1:
1873:Human chromosome 9 gene stubs
243:
142:
639:transcription, DNA-templated
1868:Genes on human chromosome 9
1889:
1796:
454:retinal pigment epithelium
438:superior cervical ganglion
1738:
1273:"Mouse PubMed Reference:"
1255:"Human PubMed Reference:"
1149:
1144:
1140:
1133:
1117:
1098:
1071:
1002:
971:
944:
875:
844:
831:
827:
812:
808:
799:
786:
782:
767:
763:
754:
741:
737:
722:
718:
709:
694:
687:
683:
667:
532:
528:
511:
495:
486:
473:
430:medullary collecting duct
422:
413:
360:
351:
321:
313:
309:
292:
279:
242:
221:
212:
208:
191:
178:
141:
118:
109:
105:
60:
57:
47:
40:
35:
26:
21:
1538:10.1093/emboj/19.10.2292
1363:10.1093/emboj/19.10.2292
1111:Chr 19: 14.43 – 14.58 Mb
603:beta-catenin-TCF complex
384:inferior olivary nucleus
1633:10.1073/pnas.0404720101
1187:TLE4 has been shown to
1104:Chr 9: 79.57 – 79.73 Mb
442:suprachiasmatic nucleus
1504:10.1093/dnares/6.5.337
634:Wnt signaling pathway
237:Chromosome 19 (mouse)
1677:10.1128/MCB.00811-06
276:19 A|19 9.11 cM
135:Chromosome 9 (human)
1624:2004PNAS..10112130B
446:conjunctival fornix
1809:This article on a
1462:10.1038/ng1092-119
789:ENSMUSG00000024642
654:biological process
612:Biological process
581:Cellular component
572:molecular function
540:Molecular function
462:olfactory tubercle
1830:
1829:
1791:
1790:
1160:
1159:
1156:
1155:
1129:
1128:
1094:
1093:
1061:
1060:
967:
966:
934:
933:
840:
839:
821:
820:
795:
794:
776:
775:
750:
749:
731:
730:
679:
678:
552:chromatin binding
524:
523:
520:
519:
482:
481:
469:
468:
450:nucleus accumbens
407:
406:
400:bone marrow cells
305:
304:
204:
203:
1880:
1851:
1844:
1837:
1805:
1798:
1777:
1762:
1747:
1727:
1720:
1713:
1704:
1698:
1688:
1655:
1645:
1635:
1602:
1592:
1559:
1549:
1532:(10): 2292–303.
1526:The EMBO Journal
1516:
1506:
1481:
1434:
1433:
1423:
1391:
1385:
1384:
1374:
1357:(10): 2292–303.
1351:The EMBO Journal
1342:
1336:
1335:
1328:
1322:
1321:
1311:
1287:
1281:
1280:
1269:
1263:
1262:
1251:
1245:
1235:
1224:
1214:
1142:
1141:
1113:
1106:
1089:
1065:
1056:
976:
972:RefSeq (protein)
962:
938:
929:
849:
825:
806:
780:
761:
735:
716:
685:
530:
516:
507:
500:
493:
478:
418:
416:Top expressed in
411:
376:endothelial cell
356:
354:Top expressed in
349:
328:
311:
301:
288:
277:
262:
255:
249:
238:
226:
210:
200:
187:
176:
161:
154:
148:
137:
123:
107:
101:
99:TLE4 - orthologs
52:
45:
31:
19:
1888:
1887:
1883:
1882:
1881:
1879:
1878:
1877:
1858:
1857:
1856:
1855:
1794:
1792:
1787:
1784:
1778:
1769:
1763:
1754:
1748:
1734:
1731:
1701:
1658:
1618:(33): 12130–5.
1605:
1562:
1519:
1484:
1450:Nature Genetics
1447:
1443:
1441:Further reading
1438:
1437:
1393:
1392:
1388:
1344:
1343:
1339:
1330:
1329:
1325:
1289:
1288:
1284:
1271:
1270:
1266:
1253:
1252:
1248:
1236:
1227:
1215:
1206:
1201:
1185:
1179:
1151:View/Edit Mouse
1146:View/Edit Human
1109:
1102:
1099:Location (UCSC)
1085:
1081:
1077:
1073:
1052:
1048:
1044:
1040:
1036:
1032:
1028:
1024:
1020:
1016:
1012:
1008:
1004:
998:
994:
990:
986:
982:
958:
954:
950:
946:
925:
921:
917:
913:
909:
905:
901:
897:
893:
889:
885:
881:
877:
871:
867:
863:
859:
855:
770:ENSG00000106829
663:
607:
576:
557:protein binding
512:
502:
501:
474:
465:
460:
456:
452:
448:
444:
440:
436:
432:
428:
426:renal corpuscle
414:
403:
398:
394:
390:
386:
382:
380:corpus callosum
378:
374:
370:
366:
352:
296:
283:
275:
265:
264:
263:
256:
236:
213:Gene location (
195:
182:
174:
164:
163:
162:
155:
133:
110:Gene location (
61:
48:
41:
17:
12:
11:
5:
1886:
1884:
1876:
1875:
1870:
1860:
1859:
1854:
1853:
1846:
1839:
1831:
1828:
1827:
1806:
1789:
1788:
1786:
1785:
1779:
1772:
1770:
1764:
1757:
1755:
1749:
1742:
1739:
1736:
1735:
1732:
1730:
1729:
1722:
1715:
1707:
1700:
1699:
1656:
1603:
1560:
1517:
1482:
1444:
1442:
1439:
1436:
1435:
1386:
1337:
1323:
1282:
1264:
1246:
1225:
1203:
1202:
1200:
1197:
1184:
1181:
1158:
1157:
1154:
1153:
1148:
1138:
1137:
1131:
1130:
1127:
1126:
1124:
1122:
1115:
1114:
1107:
1100:
1096:
1095:
1092:
1091:
1069:
1068:
1062:
1059:
1058:
1000:
999:
973:
969:
968:
965:
964:
942:
941:
935:
932:
931:
873:
872:
846:
842:
841:
838:
837:
829:
828:
822:
819:
818:
810:
809:
803:
797:
796:
793:
792:
784:
783:
777:
774:
773:
765:
764:
758:
752:
751:
748:
747:
739:
738:
732:
729:
728:
720:
719:
713:
707:
706:
701:
696:
692:
691:
681:
680:
677:
676:
665:
664:
662:
661:
656:
651:
646:
641:
636:
631:
626:
621:
615:
613:
609:
608:
606:
605:
600:
595:
590:
584:
582:
578:
577:
575:
574:
569:
564:
559:
554:
549:
543:
541:
537:
536:
526:
525:
522:
521:
518:
517:
509:
508:
490:
484:
483:
480:
479:
471:
470:
467:
466:
464:
463:
459:
458:tail of embryo
455:
451:
447:
443:
439:
435:
431:
427:
423:
420:
419:
408:
405:
404:
402:
401:
397:
393:
389:
385:
381:
377:
373:
369:
365:
361:
358:
357:
345:
344:
336:
325:
319:
318:
315:RNA expression
307:
306:
303:
302:
294:
290:
289:
281:
278:
273:
267:
266:
257:
250:
244:
240:
239:
234:
228:
227:
219:
218:
206:
205:
202:
201:
193:
189:
188:
180:
177:
172:
166:
165:
156:
149:
143:
139:
138:
131:
125:
124:
116:
115:
103:
102:
59:
55:
54:
46:
38:
37:
33:
32:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1885:
1874:
1871:
1869:
1866:
1865:
1863:
1852:
1847:
1845:
1840:
1838:
1833:
1832:
1826:
1824:
1820:
1816:
1812:
1807:
1804:
1800:
1795:
1782:
1776:
1771:
1767:
1761:
1756:
1752:
1746:
1741:
1737:
1728:
1723:
1721:
1716:
1714:
1709:
1708:
1705:
1696:
1692:
1687:
1682:
1678:
1674:
1671:(1): 340–51.
1670:
1666:
1662:
1657:
1653:
1649:
1644:
1639:
1634:
1629:
1625:
1621:
1617:
1613:
1609:
1604:
1600:
1596:
1591:
1586:
1582:
1578:
1575:(4): 447–55.
1574:
1570:
1566:
1561:
1557:
1553:
1548:
1543:
1539:
1535:
1531:
1527:
1523:
1518:
1514:
1510:
1505:
1500:
1497:(5): 337–45.
1496:
1492:
1488:
1483:
1479:
1475:
1471:
1467:
1463:
1459:
1456:(2): 119–27.
1455:
1451:
1446:
1445:
1440:
1431:
1427:
1422:
1417:
1413:
1409:
1406:(4): 447–55.
1405:
1401:
1397:
1390:
1387:
1382:
1378:
1373:
1368:
1364:
1360:
1356:
1352:
1348:
1341:
1338:
1333:
1327:
1324:
1319:
1315:
1310:
1305:
1302:(1): 343–52.
1301:
1297:
1293:
1286:
1283:
1278:
1274:
1268:
1265:
1260:
1256:
1250:
1247:
1243:
1239:
1234:
1232:
1230:
1226:
1222:
1218:
1213:
1211:
1209:
1205:
1198:
1196:
1194:
1190:
1182:
1180:
1177:
1175:
1172:
1168:
1164:
1152:
1147:
1143:
1139:
1136:
1132:
1125:
1123:
1120:
1116:
1112:
1108:
1105:
1101:
1097:
1090:
1088:
1084:
1080:
1076:
1070:
1066:
1063:
1057:
1055:
1051:
1047:
1043:
1039:
1035:
1031:
1027:
1023:
1019:
1015:
1011:
1007:
1001:
997:
993:
989:
985:
981:
977:
974:
970:
963:
961:
957:
953:
949:
943:
939:
936:
930:
928:
924:
920:
916:
912:
908:
904:
900:
896:
892:
888:
884:
880:
874:
870:
866:
862:
858:
854:
850:
847:
845:RefSeq (mRNA)
843:
836:
835:
830:
826:
823:
817:
816:
811:
807:
804:
802:
798:
791:
790:
785:
781:
778:
772:
771:
766:
762:
759:
757:
753:
746:
745:
740:
736:
733:
727:
726:
721:
717:
714:
712:
708:
705:
702:
700:
697:
693:
690:
686:
682:
675:
671:
666:
660:
657:
655:
652:
650:
647:
645:
642:
640:
637:
635:
632:
630:
627:
625:
622:
620:
617:
616:
614:
611:
610:
604:
601:
599:
596:
594:
591:
589:
586:
585:
583:
580:
579:
573:
570:
568:
565:
563:
560:
558:
555:
553:
550:
548:
545:
544:
542:
539:
538:
535:
534:Gene ontology
531:
527:
515:
510:
506:
499:
494:
491:
489:
485:
477:
472:
461:
457:
453:
449:
445:
441:
437:
433:
429:
425:
424:
421:
417:
412:
409:
399:
395:
391:
387:
383:
379:
375:
371:
367:
363:
362:
359:
355:
350:
347:
346:
343:
341:
337:
335:
334:
330:
329:
326:
324:
320:
316:
312:
308:
300:
295:
291:
287:
282:
272:
268:
261:
254:
248:
241:
233:
229:
225:
220:
216:
211:
207:
199:
194:
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186:
181:
171:
167:
160:
153:
147:
140:
136:
130:
126:
122:
117:
113:
108:
104:
100:
96:
92:
88:
84:
80:
76:
72:
68:
64:
56:
51:
44:
39:
34:
30:
25:
20:
1823:expanding it
1815:chromosome 9
1808:
1793:
1780:
1765:
1750:
1668:
1664:
1615:
1611:
1572:
1568:
1529:
1525:
1494:
1491:DNA Research
1490:
1453:
1449:
1403:
1399:
1389:
1354:
1350:
1340:
1326:
1299:
1295:
1285:
1276:
1267:
1258:
1249:
1186:
1183:Interactions
1178:
1170:
1162:
1161:
1083:NP_001289880
1079:NP_001289879
1075:NP_001289876
1072:
1054:NP_001338485
1050:NP_001338493
1046:NP_001338492
1042:NP_001338491
1038:NP_001338489
1034:NP_001338487
1030:NP_001338481
1026:NP_001338479
1022:NP_001338476
1018:NP_001338475
1014:NP_001338472
1010:NP_001338471
1006:NP_001338470
1003:
992:NP_001269689
988:NP_001269682
984:NP_001269678
980:NP_001269677
960:NM_001302951
956:NM_001302950
952:NM_001302947
945:
927:NM_001351556
923:NM_001351564
919:NM_001351563
915:NM_001351562
911:NM_001351560
907:NM_001351558
903:NM_001351552
899:NM_001351550
895:NM_001351547
891:NM_001351546
887:NM_001351543
883:NM_001351542
879:NM_001351541
876:
865:NM_001282760
861:NM_001282753
857:NM_001282749
853:NM_001282748
832:
813:
787:
768:
742:
723:
703:
698:
372:right testis
338:
331:
58:External IDs
1733:PDB gallery
593:nucleoplasm
368:left testis
364:optic nerve
297:14,575,415
284:14,425,514
196:79,726,882
183:79,571,773
36:Identifiers
1862:Categories
1569:Immunology
1400:Immunology
1244:, May 2017
1223:, May 2017
1199:References
342:(ortholog)
79:HomoloGene
1813:on human
1087:NP_035730
996:NP_008936
948:NM_011600
869:NM_007005
689:Orthologs
87:GeneCards
1695:17060451
1652:15302935
1599:12153506
1556:10811620
1513:10574462
1478:32142845
1430:12153506
1381:10811620
1240:–
1219:–
1189:interact
1135:Wikidata
668:Sources:
1686:1800652
1620:Bibcode
1590:1782747
1470:1303260
1421:1782747
1318:8365415
1242:Ensembl
1221:Ensembl
1167:protein
801:UniProt
756:Ensembl
695:Species
674:QuickGO
588:nucleus
317:pattern
175:9q21.31
43:Aliases
1693:
1683:
1650:
1643:514446
1640:
1597:
1587:
1554:
1547:384353
1544:
1511:
1476:
1468:
1428:
1418:
1379:
1372:384353
1369:
1316:
1121:search
1119:PubMed
834:Q62441
815:Q04727
711:Entrez
488:BioGPS
75:104633
67:605132
1817:is a
1474:S2CID
1191:with
1165:is a
744:21888
704:Mouse
699:Human
670:Amigo
340:Mouse
333:Human
280:Start
215:Mouse
179:Start
112:Human
83:38259
1819:stub
1811:gene
1781:2ce9
1766:2ce8
1751:1gxr
1691:PMID
1648:PMID
1595:PMID
1552:PMID
1509:PMID
1466:PMID
1426:PMID
1377:PMID
1314:PMID
1193:PAX5
1174:gene
1171:TLE4
725:7091
323:Bgee
271:Band
232:Chr.
170:Band
129:Chr.
91:TLE4
63:OMIM
50:TLE4
22:TLE4
1681:PMC
1673:doi
1638:PMC
1628:doi
1616:101
1585:PMC
1577:doi
1573:106
1542:PMC
1534:doi
1499:doi
1458:doi
1416:PMC
1408:doi
1404:106
1367:PMC
1359:doi
1304:doi
1300:216
293:End
192:End
95:OMA
71:MGI
1864::
1689:.
1679:.
1669:27
1667:.
1663:.
1646:.
1636:.
1626:.
1614:.
1610:.
1593:.
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1571:.
1567:.
1550:.
1540:.
1530:19
1528:.
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1398:.
1375:.
1365:.
1355:19
1353:.
1349:.
1312:.
1298:.
1294:.
1275:.
1257:.
1228:^
1207:^
1195:.
1176:.
672:/
299:bp
286:bp
198:bp
185:bp
93:;
89::
85:;
81::
77:;
73::
69:;
65::
1850:e
1843:t
1836:v
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1726:e
1719:t
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217:)
114:)
97::
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