242:
219:
116:
141:
493:
248:
147:
1311:
1200:
Kaneko R, Tsuji N, Kamagata C, et al. (2002). "Amount of expression of the tumor-associated antigen L6 gene and transmembrane 4 superfamily member 5 gene in gastric cancers and gastric mucosa".
979:
Muller-Pillasch F, Wallrapp C, Lacher U, Friess H, Buchler M, Adler G, Gress TM (Mar 1998). "Identification of a new tumour-associated antigen TM4SF5 and its expression in human cancer".
255:
154:
1065:
Lee SY, Kim YT, Lee MS, et al. (2006). "Focal adhesion and actin organization by a cross-talk of TM4SF5 with integrin alpha2 are regulated by serum treatment".
576:
557:
77:
1380:
1356:
1375:
961:
943:
241:
779:
218:
772:
1017:
930:
909:
140:
115:
926:
905:
57:
254:
153:
1349:
247:
146:
876:
and is highly similar in sequence and structure to transmembrane 4 superfamily member 1. It may play a role in
621:
65:
1106:"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)"
1280:
Gress TM, Müller-Pillasch F, Geng M, et al. (1996). "A pancreatic cancer-specific expression profile".
602:
1342:
129:
1160:
44:
861:
848:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the
1225:
877:
89:
1149:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"
736:
710:
689:
1289:
1268:
1217:
1188:
1135:
1092:
1053:
996:
37:
1326:
1036:
Berditchevski F (2002). "Complexes of tetraspanins with integrins: more than meets the eye".
1258:
1250:
1209:
1178:
1168:
1125:
1117:
1082:
1074:
1045:
988:
492:
334:
265:
209:
164:
85:
309:
1164:
1263:
1238:
880:, and overexpression of this protein may be associated with the uncontrolled growth of
1183:
1148:
1130:
1105:
992:
1369:
1322:
1213:
869:
1229:
69:
881:
873:
853:
327:
106:
93:
1078:
966:
National Center for
Biotechnology Information, U.S. National Library of Medicine
948:
National Center for
Biotechnology Information, U.S. National Library of Medicine
865:
857:
849:
410:
226:
123:
73:
1049:
521:
470:
348:
293:
280:
192:
179:
81:
1272:
1221:
1192:
1173:
1139:
1096:
1057:
864:
events that play a role in the regulation of cell development, activation,
1293:
1000:
819:
814:
803:
647:
1254:
1121:
835:
633:
588:
1087:
787:
543:
1310:
1318:
1239:"The L6 membrane proteins--a new four-transmembrane superfamily"
842:
61:
501:
1147:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
1018:"Entrez Gene: TM4SF5 transmembrane 4 L six family member 5"
856:
proteins that are characterized by the presence of four
317:
1330:
1104:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
482:
750:
729:
703:
682:
922:
920:
918:
901:
899:
897:
264:
163:
16:Protein-coding gene in the species Homo sapiens
927:GRCm38: Ensembl release 89: ENSMUSG00000018919
1350:
8:
906:GRCh38: Ensembl release 89: ENSG00000142484
1357:
1343:
517:
305:
204:
101:
1262:
1182:
1172:
1129:
1086:
872:. This encoded protein is a cell surface
1012:
1010:
893:
48:, transmembrane 4 L six family member 5
433:crypt of lieberkuhn of small intestine
18:
269:
230:
225:
168:
127:
122:
7:
1307:
1305:
441:vestibular membrane of cochlear duct
429:migratory enteric neural crest cell
1329:. You can help Knowledge (XXG) by
852:family. Most of these members are
832:Transmembrane 4 L6 family member 5
747:
726:
700:
679:
657:
638:
612:
593:
567:
548:
487:
405:
343:
322:
14:
1237:Wright MD, Ni J, Rudy GB (2000).
838:that in humans is encoded by the
1309:
1214:10.1111/j.1572-0241.2001.05355.x
491:
253:
246:
240:
217:
152:
145:
139:
114:
1381:Human chromosome 17 gene stubs
860:domains. The proteins mediate
502:More reference expression data
471:More reference expression data
1:
993:10.1016/S0378-1119(97)00633-1
449:epithelium of small intestine
238:
137:
1376:Genes on human chromosome 17
1153:Proc. Natl. Acad. Sci. U.S.A
1079:10.1016/j.yexcr.2006.06.001
1397:
1304:
375:mucosa of transverse colon
962:"Mouse PubMed Reference:"
944:"Human PubMed Reference:"
818:
813:
809:
802:
786:
767:
754:
733:
722:
707:
686:
675:
664:
660:
645:
641:
632:
619:
615:
600:
596:
587:
574:
570:
555:
551:
542:
527:
520:
516:
499:
490:
481:
468:
417:
408:
355:
346:
316:
308:
304:
287:
274:
237:
216:
207:
203:
186:
173:
136:
113:
104:
100:
55:
52:
42:
35:
30:
26:
21:
1050:10.1242/jcs.114.23.4143
1174:10.1073/pnas.242603899
780:Chr 11: 70.4 – 70.4 Mb
773:Chr 17: 4.77 – 4.78 Mb
453:mucous cell of stomach
445:intestinal epithelium
232:Chromosome 11 (mouse)
130:Chromosome 17 (human)
1202:Am. J. Gastroenterol
1255:10.1110/ps.9.8.1594
1165:2002PNAS...9916899M
862:signal transduction
363:right lobe of liver
1317:This article on a
1122:10.1101/gr.2596504
1044:(Pt 23): 4143–51.
878:cell proliferation
622:ENSMUSG00000018919
94:TM4SF5 - orthologs
1338:
1337:
1159:(26): 16899–903.
829:
828:
825:
824:
798:
797:
763:
762:
744:
743:
718:
717:
697:
696:
671:
670:
654:
653:
628:
627:
609:
608:
583:
582:
564:
563:
512:
511:
508:
507:
477:
476:
464:
463:
457:intestinal villus
402:
401:
300:
299:
199:
198:
1388:
1359:
1352:
1345:
1313:
1306:
1297:
1276:
1266:
1233:
1196:
1186:
1176:
1143:
1133:
1100:
1090:
1061:
1022:
1021:
1014:
1005:
1004:
976:
970:
969:
958:
952:
951:
940:
934:
924:
913:
903:
811:
810:
782:
775:
758:
748:
739:
727:
723:RefSeq (protein)
713:
701:
692:
680:
658:
639:
613:
594:
568:
549:
518:
504:
495:
488:
473:
413:
411:Top expressed in
406:
351:
349:Top expressed in
344:
323:
306:
296:
283:
272:
257:
250:
244:
233:
221:
205:
195:
182:
171:
156:
149:
143:
132:
118:
102:
96:
47:
40:
19:
1396:
1395:
1391:
1390:
1389:
1387:
1386:
1385:
1366:
1365:
1364:
1363:
1302:
1300:
1279:
1249:(8): 1594–600.
1236:
1199:
1146:
1116:(10B): 2121–7.
1103:
1073:(16): 2983–99.
1064:
1035:
1031:
1029:Further reading
1026:
1025:
1016:
1015:
1008:
978:
977:
973:
960:
959:
955:
942:
941:
937:
925:
916:
904:
895:
890:
820:View/Edit Mouse
815:View/Edit Human
778:
771:
768:Location (UCSC)
756:
735:
709:
688:
603:ENSG00000142484
500:
469:
460:
455:
451:
447:
443:
439:
435:
431:
427:
423:
409:
398:
393:
389:
385:
381:
377:
373:
371:mucosa of ileum
369:
365:
361:
347:
291:
278:
270:
260:
259:
258:
251:
231:
208:Gene location (
190:
177:
169:
159:
158:
157:
150:
128:
105:Gene location (
56:
43:
36:
17:
12:
11:
5:
1394:
1392:
1384:
1383:
1378:
1368:
1367:
1362:
1361:
1354:
1347:
1339:
1336:
1335:
1314:
1299:
1298:
1288:(8): 1819–30.
1277:
1234:
1208:(12): 3457–8.
1197:
1144:
1101:
1062:
1032:
1030:
1027:
1024:
1023:
1006:
971:
953:
935:
914:
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891:
889:
886:
827:
826:
823:
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698:
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684:
683:
677:
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669:
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636:
630:
629:
626:
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617:
616:
610:
607:
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591:
585:
584:
581:
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572:
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438:
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430:
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422:
418:
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414:
403:
400:
399:
397:
396:
392:
388:
384:
380:
376:
372:
368:
364:
360:
359:jejunal mucosa
356:
353:
352:
340:
339:
331:
320:
314:
313:
310:RNA expression
302:
301:
298:
297:
289:
285:
284:
276:
273:
268:
262:
261:
252:
245:
239:
235:
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188:
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175:
172:
167:
161:
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144:
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133:
126:
120:
119:
111:
110:
98:
97:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1393:
1382:
1379:
1377:
1374:
1373:
1371:
1360:
1355:
1353:
1348:
1346:
1341:
1340:
1334:
1332:
1328:
1324:
1323:chromosome 17
1320:
1315:
1312:
1308:
1303:
1295:
1291:
1287:
1283:
1278:
1274:
1270:
1265:
1260:
1256:
1252:
1248:
1244:
1240:
1235:
1231:
1227:
1223:
1219:
1215:
1211:
1207:
1203:
1198:
1194:
1190:
1185:
1180:
1175:
1170:
1166:
1162:
1158:
1154:
1150:
1145:
1141:
1137:
1132:
1127:
1123:
1119:
1115:
1111:
1107:
1102:
1098:
1094:
1089:
1084:
1080:
1076:
1072:
1068:
1067:Exp. Cell Res
1063:
1059:
1055:
1051:
1047:
1043:
1039:
1034:
1033:
1028:
1019:
1013:
1011:
1007:
1002:
998:
994:
990:
986:
982:
975:
972:
967:
963:
957:
954:
949:
945:
939:
936:
932:
928:
923:
921:
919:
915:
911:
907:
902:
900:
898:
894:
887:
885:
883:
879:
875:
871:
867:
863:
859:
855:
851:
846:
844:
841:
837:
833:
821:
816:
812:
808:
805:
801:
794:
792:
789:
785:
781:
777:
774:
770:
766:
759:
753:
749:
746:
740:
738:
732:
728:
725:
721:
714:
712:
706:
702:
699:
693:
691:
685:
681:
678:
676:RefSeq (mRNA)
674:
667:
663:
659:
656:
650:
649:
644:
640:
637:
635:
631:
624:
623:
618:
614:
611:
605:
604:
599:
595:
592:
590:
586:
579:
578:
573:
569:
566:
560:
559:
554:
550:
547:
545:
541:
538:
535:
533:
530:
526:
523:
519:
515:
503:
498:
494:
489:
486:
484:
480:
472:
467:
456:
452:
448:
444:
440:
436:
432:
428:
424:
420:
419:
416:
412:
407:
404:
394:
390:
387:kidney tubule
386:
382:
378:
374:
370:
366:
362:
358:
357:
354:
350:
345:
342:
341:
338:
336:
332:
330:
329:
325:
324:
321:
319:
315:
311:
307:
303:
295:
290:
286:
282:
277:
271:11|11 B3
267:
263:
256:
249:
243:
236:
228:
224:
220:
215:
211:
206:
202:
194:
189:
185:
181:
176:
166:
162:
155:
148:
142:
135:
131:
125:
121:
117:
112:
108:
103:
99:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
1331:expanding it
1316:
1301:
1285:
1281:
1246:
1242:
1205:
1201:
1156:
1152:
1113:
1109:
1070:
1066:
1041:
1037:
987:(1): 25–30.
984:
980:
974:
965:
956:
947:
938:
882:tumour cells
874:glycoprotein
854:cell-surface
847:
839:
831:
830:
755:
734:
708:
687:
665:
646:
620:
601:
575:
556:
536:
531:
395:human kidney
333:
326:
53:External IDs
1243:Protein Sci
1038:J. Cell Sci
858:hydrophobic
850:tetraspanin
292:70,402,004
279:70,396,070
31:Identifiers
1370:Categories
1110:Genome Res
1088:10371/3238
933:, May 2017
912:, May 2017
888:References
337:(ortholog)
191:4,783,213
178:4,771,884
74:HomoloGene
1321:on human
737:NP_003954
711:NM_029360
690:NM_003963
522:Orthologs
82:GeneCards
1282:Oncogene
1273:10975581
1230:31864317
1222:11774983
1193:12477932
1140:15489334
1097:16828471
1058:11739647
929:–
908:–
870:motility
804:Wikidata
421:duodenum
379:testicle
367:duodenum
1294:8895530
1264:2144728
1161:Bibcode
1001:9479038
931:Ensembl
910:Ensembl
836:protein
634:UniProt
589:Ensembl
528:Species
425:jejunum
312:pattern
170:17p13.2
70:1922854
38:Aliases
1292:
1271:
1261:
1228:
1220:
1191:
1184:139241
1181:
1138:
1131:528928
1128:
1095:
1056:
999:
866:growth
840:TM4SF5
790:search
788:PubMed
648:O14894
544:Entrez
483:BioGPS
391:rectum
86:TM4SF5
62:604657
45:TM4SF5
22:TM4SF5
1325:is a
1226:S2CID
834:is a
577:75604
537:Mouse
532:Human
437:ileum
383:gonad
335:Mouse
328:Human
275:Start
210:Mouse
174:Start
107:Human
1327:stub
1319:gene
1290:PMID
1269:PMID
1218:PMID
1189:PMID
1136:PMID
1093:PMID
1054:PMID
997:PMID
981:Gene
868:and
843:gene
558:9032
318:Bgee
266:Band
227:Chr.
165:Band
124:Chr.
78:2947
58:OMIM
1259:PMC
1251:doi
1210:doi
1179:PMC
1169:doi
1126:PMC
1118:doi
1083:hdl
1075:doi
1071:312
1046:doi
1042:114
989:doi
985:208
757:n/a
666:n/a
288:End
187:End
90:OMA
66:MGI
1372::
1286:13
1284:.
1267:.
1257:.
1245:.
1241:.
1224:.
1216:.
1206:96
1204:.
1187:.
1177:.
1167:.
1157:99
1155:.
1151:.
1134:.
1124:.
1114:14
1112:.
1108:.
1091:.
1081:.
1069:.
1052:.
1040:.
1009:^
995:.
983:.
964:.
946:.
917:^
896:^
884:.
845:.
294:bp
281:bp
193:bp
180:bp
88:;
84::
80:;
76::
72:;
68::
64:;
60::
1358:e
1351:t
1344:v
1333:.
1296:.
1275:.
1253::
1247:9
1232:.
1212::
1195:.
1171::
1163::
1142:.
1120::
1099:.
1085::
1077::
1060:.
1048::
1020:.
1003:.
991::
968:.
950:.
212:)
109:)
92::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
