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TMEM131

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1839: 242: 982: 219: 116: 141: 1092: 1110: 248: 147: 1133:. It has been shown to contain two transmembrane domains at residues 1,091-1,111 and 1,118-1,138. Three DUF3651 regions are located on the N-terminal side of the two adjacent transmembrane domains. These are located at residues 173-245, 502-582, and 639-708. The intercellular location of the protein has not been experimentally determined, but it is thought to reside in either the 1062: 1019:
through the Genomatix software page. The predicted promoter region spans 1002 base pairs from 98,611,892 through 98,612,893 on the minus strand of chromosome 2. The program predicted two potential transcriptional start locations. The first spans 216 base pairs from 98,612,501 through 98,612,716. The
1141:, with each domain on both the N-terminal and C-terminal sides of the transmembrane regions being cytosolic. It contains numerous phosphorylation sites which have been shown both experimentally and with bioinformatic tools. Bioinformatic analysis of the protein using the 1158:, although none of these should be considered actual protein-protein interactions. Closer analysis of the results shows very little potential for these predictions to be real. The IntAct tool was also used, and this revealed a potential interaction had been found with 964:. The authors of this study proposed that, given TMEM131s supposed function in T cell development and function, this hypermethylation may play a role in the suppressed immune function in patients with Down Syndrome. 1153:
Protein interaction analysis for TMEM131 has been carried out using computational tools. No interactions were identified through the MINT database. A STRING search revealed ten possible protein interactions through
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TMEM131 has also been shown to be up-regulated during the development and differentiation of T cells, and has been shown to have relatively high levels of expression in T cells relative to other tissue types.
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in the human gene. Ensembl predicts ten alternative splice forms, four of which are protein coding. Promoter prediction and analysis was carried out using
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and the ALIGN tool through the San Diego Super Computer Biology Workbench. The following table gives information on the homologs of TMEM131.
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Steucgen-Gersdorf, E (December 2008). "Triangular tibia with fibular aplasia associated with a microdeletion on 2q11.2 encompassing LAF4".
241: 856: 863: 218: 2028: 1586: 1565: 1582: 140: 115: 1881: 1561: 2079: 985:
Predicted promoter sequence layout as well as potential transcriptional start sites (TSS) as predicted by the Genomatix
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is expressed in low to moderate levels throughout most of the body, with slightly increased levels occurring in the
247: 146: 997: 981: 942: 697: 65: 1541:. This gene is very similar to TMEM131, but it does not include the second two of the three DUF3651 regions. 1475: 678: 1952: 1500: 1450: 1350: 1213: 1138: 1046: 1923: 1194:
orthologs, while conservation is high within the DUF3651 and transmembrane regions in the more distant
1980: 1091: 1170: 930: 129: 44: 1095:
Expression profile from 79 physiologically normal tissues obtained from various sources for TMEM131.
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in humans. The TMEM131 protein contains three domains of unknown function 3651 (DUF3651) and two
1840:"GDS596 / TMEM131 / Homo Sapiens - Gene expression profile from 79 physiologically normal tissues" 1816: 1400: 1195: 1145:
tool predicted 145 potential phosphorylation sites throughout the entire length of the protein.
89: 1745:"Molecular Dissection of Prethymic Progenitor Entry into the T Lymphocyte Developmental Pathway" 839: 818: 792: 771: 767: 2430: 2188: 2048: 1808: 1766: 1722: 1122: 37: 2115: 85: 2178: 2170: 2040: 1800: 1756: 1712: 1702: 1206: 1117:
The primary function of the TMEM131 protein is not well understood. The human form has 1883
1042: 334: 265: 209: 164: 1109: 1275: 1134: 309: 2157:
Chenna R, Sugawara H, Koike T, Lopez R, Gibson TJ, Higgins DG, Thompson JD (July 2003).
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and T cells. Expression data in developing fruit fly embryos is available from the BDGP
1717: 1690: 1126: 2409: 2183: 2158: 2056: 2029:"Sequence- and structure-based prediction of eukaryotic protein phosphorylation sites" 567: 551: 546: 541: 525: 2450: 1804: 1375: 1130: 961: 512: 2101: 1820: 69: 2388: 2276: 2255: 1325: 1250: 1001: 327: 106: 2367: 2353: 2332: 2318: 2297: 2234: 1744: 1707: 1644: 93: 1622:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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gene (98,330,331 - 98,356,323) on the positive DNA strand, as well as numerous
410: 1300: 1118: 1077: 1038: 226: 123: 73: 1187: 1005: 597: 470: 348: 293: 280: 192: 179: 81: 2192: 2052: 2044: 1812: 1770: 1726: 2206: 2006: 1665: 1061: 903: 898: 2174: 1537: 887: 742: 723: 1225: 1191: 919: 709: 664: 1202: 1081: 934: 871: 619: 1222: 1167: 1108: 1090: 1060: 1033: 1012: 980: 2159:"Multiple sequence alignment with the Clustal series of programs" 582: 578: 1163: 1020:
second spans 182 base pairs from 98,612,262 through 98,612,443.
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from 98,372,799 - 98,612,354. The gene product is a 6,657
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also resides in a locus (2q11.1) that is associated with
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Orthologs were found in species as distantly related to
1069:
hybridization data available from BDGP (stage 11 shown).
933:. This protein has been implicated as having a role in 317: 1691:"Altered DNA Methylation in Leukocytes with Trisomy 21" 1876: 1874: 48:, CC28, PRO1048, RW1, YR-23, transmembrane protein 131 1684: 1682: 482: 1639: 1637: 1635: 1633: 1631: 832: 811: 785: 760: 1975: 1973: 1971: 1969: 1578: 1576: 1574: 1557: 1555: 1553: 1053:on the positive strand (98,703,595 - 98,929,410). 1049:containing gene (VWA3B) is located upstream from 264: 163: 1113:Schematic representation of the TMEM131 protein. 16:Protein-coding gene in the species Homo sapiens 1583:GRCm38: Ensembl release 89: ENSMUSG00000026116 2027:Blom, N.; Gammeltoft, S.; Brunak, S. (1999). 8: 1851: 1849: 1190:. The entire protein is highly conserved in 1562:GRCh38: Ensembl release 89: ENSG00000075568 1186:TMEM131 is conserved throughout all of its 996:is located on the negative DNA strand (see 1218: 593: 508: 305: 204: 101: 2182: 1834: 1832: 1830: 1760: 1716: 1706: 429:fetal liver hematopoietic progenitor cell 1549: 18: 269: 230: 225: 168: 127: 122: 7: 1031:is located directly adjacent to the 441:migratory enteric neural crest cell 1166:), which had been identified in a 829: 808: 782: 757: 733: 714: 688: 669: 643: 624: 487: 405: 343: 322: 14: 2410:"NCBI Nucleotide: XP_001744482.1" 2354:"NCBI Nucleotide: XP_001923340.1" 2298:"NCBI Nucleotide: XM_001367646.2" 2319:"NCBI Nucleotide:XM_001233588.2" 1805:10.1111/j.1399-0004.2008.01050.x 1689:Kerkel, Kristi (November 2010). 253: 246: 240: 217: 152: 145: 139: 114: 2333:"NCBI Nucleotide: NP_001135552" 2389:"NCBI Nucleotide: NP_611073.2" 2368:"NCBI Nucleotide: NP_498059.2" 2277:"NCBI Nucleotide: NP_061360.2" 2235:"NCBI Nucleotide: XP_515638.2" 1531:TMEM131 has a single paralog, 547:integral component of membrane 471:More reference expression data 1: 1743:Tydell, Chace (1 July 2007). 1470:Hypothetical Protein C27F2.8 1236:NCBI Protein Accession Number 1233:Divergence from Humans (MYA) 238: 137: 2256:"NCBI Nucleotide: XP_613474" 2033:Journal of Molecular Biology 1708:10.1371/journal.pgen.1001212 2457:Genes on human chromosome 2 1926:. Genomatix. Archived from 2473: 1762:10.4049/jimmunol.179.1.421 1105:Properties/Characteristics 956:has been shown to exhibit 937:function and development. 1749:The Journal of Immunology 1618:"Mouse PubMed Reference:" 1600:"Human PubMed Reference:" 916:Transmembrane protein 131 902: 897: 893: 886: 870: 851: 836: 815: 804: 789: 764: 753: 740: 736: 721: 717: 708: 695: 691: 676: 672: 663: 650: 646: 631: 627: 618: 603: 596: 592: 576: 511: 507: 495: 490: 481: 468: 417: 408: 375:mucosa of paranasal sinus 359:bronchial epithelial cell 355: 346: 316: 308: 304: 287: 274: 237: 216: 207: 203: 186: 173: 136: 113: 104: 100: 55: 52: 42: 35: 30: 26: 21: 1981:"SDSC Biology Workbench" 1645:"NCBI Protein: TMEM131" 1476:Drosophila melanogaster 949:Role In T Cell Function 922:that is encoded by the 864:Chr 1: 36.83 – 36.98 Mb 363:mucosa of sigmoid colon 2045:10.1006/jmbi.1999.3310 1451:Caenorhabditis elegans 1160:Superoxide dismutase 2 1114: 1096: 1070: 990: 2431:"GeneCards: TMEM131L" 1520:Hypothetical Protein 1351:Monodelphis domestica 1139:endoplasmic reticulum 1112: 1094: 1064: 1047:Von Willebrand factor 984: 943:Nievergelt's Syndrome 931:transmembrane domains 1501:Monosiga brevicollis 1230:Organism Common Name 1210:Monosiga brevicollis 1171:Two-hybrid screening 1149:Protein Interactions 857:Chr 2: 97.76 – 98 Mb 453:skin of external ear 232:Chromosome 1 (mouse) 130:Chromosome 2 (human) 1445:Predicted: TMEM131 425:submandibular gland 271:1 B|1 15.42 cM 94:TMEM131 - orthologs 2175:10.1093/nar/gkg500 1930:on 2 December 2021 1903:"Ensembl: TMEM131" 1401:Xenopus tropicalis 1239:Sequence Identity 1121:residues, with an 1115: 1097: 1071: 1011:with 41 predicted 991: 698:ENSMUSG00000026116 568:biological process 561:Biological process 552:cellular component 535:Cellular component 526:molecular function 519:Molecular function 2163:Nucleic Acids Res 2080:"NetPhos TMEM131" 2059:on 10 August 2021 1987:on 11 August 2003 1793:Clinical Genetics 1524: 1523: 1245:Common Gene Name 1123:isoelectric point 1024:Gene Neighborhood 960:in patients with 913: 912: 909: 908: 882: 881: 847: 846: 826: 825: 800: 799: 779: 778: 749: 748: 730: 729: 704: 703: 685: 684: 659: 658: 640: 639: 588: 587: 503: 502: 499: 498: 477: 476: 464: 463: 402: 401: 300: 299: 199: 198: 2464: 2442: 2441: 2439: 2437: 2427: 2421: 2420: 2418: 2416: 2406: 2400: 2399: 2397: 2395: 2385: 2379: 2378: 2376: 2374: 2364: 2358: 2357: 2350: 2344: 2343: 2341: 2339: 2329: 2323: 2322: 2315: 2309: 2308: 2306: 2304: 2294: 2288: 2287: 2285: 2283: 2273: 2267: 2266: 2264: 2262: 2252: 2246: 2245: 2243: 2241: 2231: 2225: 2224: 2217: 2211: 2210: 2203: 2197: 2196: 2186: 2169:(13): 3497–500. 2154: 2148: 2147: 2145: 2143: 2137:"IntAct TMEM131" 2133: 2127: 2126: 2124: 2122: 2116:"STRING TMEM131" 2112: 2106: 2105: 2098: 2092: 2091: 2089: 2087: 2075: 2069: 2068: 2066: 2064: 2055:. Archived from 2039:(5): 1351–1362. 2024: 2018: 2017: 2015: 2013: 2003: 1997: 1996: 1994: 1992: 1983:. Archived from 1977: 1964: 1963: 1961: 1959: 1949: 1940: 1939: 1937: 1935: 1920: 1914: 1913: 1911: 1909: 1899: 1893: 1892: 1890: 1888: 1882:"TMEM131: 23505" 1878: 1869: 1868: 1866: 1864: 1853: 1844: 1843: 1836: 1825: 1824: 1788: 1782: 1781: 1779: 1777: 1764: 1740: 1731: 1730: 1720: 1710: 1701:(11): e1001212. 1686: 1677: 1676: 1674: 1672: 1662: 1656: 1655: 1653: 1651: 1641: 1626: 1625: 1614: 1608: 1607: 1596: 1590: 1580: 1569: 1559: 1505:Choanoflagellate 1219: 1207:Choanoflagellate 958:hypermethylation 895: 894: 866: 859: 842: 830: 821: 809: 805:RefSeq (protein) 795: 783: 774: 758: 734: 715: 689: 670: 644: 625: 594: 509: 488: 473: 433:genital tubercle 413: 411:Top expressed in 406: 351: 349:Top expressed in 344: 323: 306: 296: 283: 272: 257: 250: 244: 233: 221: 205: 195: 182: 171: 156: 149: 143: 132: 118: 102: 96: 47: 40: 19: 2472: 2471: 2467: 2466: 2465: 2463: 2462: 2461: 2447: 2446: 2445: 2435: 2433: 2429: 2428: 2424: 2414: 2412: 2408: 2407: 2403: 2393: 2391: 2387: 2386: 2382: 2372: 2370: 2366: 2365: 2361: 2352: 2351: 2347: 2337: 2335: 2331: 2330: 2326: 2317: 2316: 2312: 2302: 2300: 2296: 2295: 2291: 2281: 2279: 2275: 2274: 2270: 2260: 2258: 2254: 2253: 2249: 2239: 2237: 2233: 2232: 2228: 2219: 2218: 2214: 2205: 2204: 2200: 2156: 2155: 2151: 2141: 2139: 2135: 2134: 2130: 2120: 2118: 2114: 2113: 2109: 2100: 2099: 2095: 2085: 2083: 2077: 2076: 2072: 2062: 2060: 2026: 2025: 2021: 2011: 2009: 2007:"Expasy: Psort" 2005: 2004: 2000: 1990: 1988: 1979: 1978: 1967: 1957: 1955: 1951: 1950: 1943: 1933: 1931: 1922: 1921: 1917: 1907: 1905: 1901: 1900: 1896: 1886: 1884: 1880: 1879: 1872: 1862: 1860: 1855: 1854: 1847: 1838: 1837: 1828: 1790: 1789: 1785: 1775: 1773: 1742: 1741: 1734: 1688: 1687: 1680: 1670: 1668: 1664: 1663: 1659: 1649: 1647: 1643: 1642: 1629: 1616: 1615: 1611: 1598: 1597: 1593: 1581: 1572: 1560: 1551: 1547: 1529: 1276:Pan troglodytes 1184: 1179: 1151: 1135:plasma membrane 1107: 1102: 1059: 1057:Gene Expression 1026: 979: 974: 951: 918:(TMEM131) is a 904:View/Edit Mouse 899:View/Edit Human 862: 855: 852:Location (UCSC) 838: 817: 791: 770: 766: 679:ENSG00000075568 572: 556: 530: 469: 460: 455: 451: 447: 443: 439: 435: 431: 427: 423: 409: 398: 393: 389: 387:trabecular bone 385: 381: 377: 373: 369: 365: 361: 347: 291: 278: 270: 260: 259: 258: 251: 231: 208:Gene location ( 190: 177: 169: 159: 158: 157: 150: 128: 105:Gene location ( 56: 43: 36: 17: 12: 11: 5: 2470: 2468: 2460: 2459: 2449: 2448: 2444: 2443: 2422: 2401: 2380: 2359: 2345: 2324: 2310: 2289: 2268: 2247: 2226: 2212: 2198: 2149: 2128: 2107: 2102:"MINT TMEM131" 2093: 2070: 2019: 1998: 1965: 1953:"BDGP in situ" 1941: 1915: 1894: 1870: 1845: 1826: 1783: 1755:(1): 421–438. 1732: 1678: 1657: 1627: 1609: 1591: 1570: 1548: 1546: 1543: 1528: 1525: 1522: 1521: 1518: 1515: 1512: 1511:XP_001744482.1 1509: 1506: 1503: 1497: 1496: 1493: 1490: 1487: 1484: 1481: 1478: 1472: 1471: 1468: 1465: 1462: 1459: 1456: 1453: 1447: 1446: 1443: 1440: 1437: 1436:XP_001923340.1 1434: 1431: 1428: 1422: 1421: 1418: 1415: 1412: 1409: 1406: 1403: 1397: 1396: 1393: 1390: 1387: 1386:XM_001233588.2 1384: 1381: 1378: 1372: 1371: 1368: 1365: 1362: 1361:XM_001367646.2 1359: 1356: 1353: 1347: 1346: 1343: 1340: 1337: 1334: 1331: 1328: 1322: 1321: 1318: 1315: 1312: 1309: 1306: 1303: 1297: 1296: 1293: 1290: 1287: 1284: 1281: 1278: 1272: 1271: 1268: 1265: 1262: 1259: 1256: 1253: 1247: 1246: 1243: 1242:Protein Length 1240: 1237: 1234: 1231: 1228: 1183: 1180: 1178: 1175: 1150: 1147: 1127:molecular mass 1125:of 8.74 and a 1106: 1103: 1101: 1098: 1058: 1055: 1041:at the 2q11.2 1025: 1022: 978: 975: 973: 970: 950: 947: 945:when deleted. 911: 910: 907: 906: 901: 891: 890: 884: 883: 880: 879: 877: 875: 868: 867: 860: 853: 849: 848: 845: 844: 834: 833: 827: 824: 823: 813: 812: 806: 802: 801: 798: 797: 787: 786: 780: 777: 776: 762: 761: 755: 751: 750: 747: 746: 738: 737: 731: 728: 727: 719: 718: 712: 706: 705: 702: 701: 693: 692: 686: 683: 682: 674: 673: 667: 661: 660: 657: 656: 648: 647: 641: 638: 637: 629: 628: 622: 616: 615: 610: 605: 601: 600: 590: 589: 586: 585: 574: 573: 571: 570: 564: 562: 558: 557: 555: 554: 549: 544: 538: 536: 532: 531: 529: 528: 522: 520: 516: 515: 505: 504: 501: 500: 497: 496: 493: 492: 485: 479: 478: 475: 474: 466: 465: 462: 461: 459: 458: 454: 450: 449:abdominal wall 446: 442: 438: 437:tail of embryo 434: 430: 426: 422: 418: 415: 414: 403: 400: 399: 397: 396: 392: 388: 384: 380: 376: 372: 368: 367:jejunal mucosa 364: 360: 356: 353: 352: 340: 339: 331: 320: 314: 313: 310:RNA expression 302: 301: 298: 297: 289: 285: 284: 276: 273: 268: 262: 261: 252: 245: 239: 235: 234: 229: 223: 222: 214: 213: 201: 200: 197: 196: 188: 184: 183: 175: 172: 167: 161: 160: 151: 144: 138: 134: 133: 126: 120: 119: 111: 110: 98: 97: 54: 50: 49: 41: 33: 32: 28: 27: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 2469: 2458: 2455: 2454: 2452: 2432: 2426: 2423: 2411: 2405: 2402: 2390: 2384: 2381: 2369: 2363: 2360: 2355: 2349: 2346: 2334: 2328: 2325: 2320: 2314: 2311: 2299: 2293: 2290: 2278: 2272: 2269: 2257: 2251: 2248: 2236: 2230: 2227: 2222: 2216: 2213: 2208: 2202: 2199: 2194: 2190: 2185: 2180: 2176: 2172: 2168: 2164: 2160: 2153: 2150: 2138: 2132: 2129: 2117: 2111: 2108: 2103: 2097: 2094: 2081: 2074: 2071: 2058: 2054: 2050: 2046: 2042: 2038: 2034: 2030: 2023: 2020: 2008: 2002: 1999: 1986: 1982: 1976: 1974: 1972: 1970: 1966: 1954: 1948: 1946: 1942: 1929: 1925: 1919: 1916: 1904: 1898: 1895: 1883: 1877: 1875: 1871: 1858: 1852: 1850: 1846: 1841: 1835: 1833: 1831: 1827: 1822: 1818: 1814: 1810: 1806: 1802: 1798: 1794: 1787: 1784: 1772: 1768: 1763: 1758: 1754: 1750: 1746: 1739: 1737: 1733: 1728: 1724: 1719: 1714: 1709: 1704: 1700: 1696: 1692: 1685: 1683: 1679: 1667: 1661: 1658: 1646: 1640: 1638: 1636: 1634: 1632: 1628: 1623: 1619: 1613: 1610: 1605: 1601: 1595: 1592: 1588: 1584: 1579: 1577: 1575: 1571: 1567: 1563: 1558: 1556: 1554: 1550: 1544: 1542: 1540: 1539: 1534: 1526: 1519: 1516: 1513: 1510: 1507: 1504: 1502: 1499: 1498: 1494: 1491: 1488: 1485: 1482: 1479: 1477: 1474: 1473: 1469: 1466: 1463: 1460: 1457: 1454: 1452: 1449: 1448: 1444: 1441: 1438: 1435: 1432: 1429: 1427: 1424: 1423: 1419: 1416: 1413: 1410: 1407: 1404: 1402: 1399: 1398: 1394: 1391: 1388: 1385: 1382: 1379: 1377: 1376:Gallus gallus 1374: 1373: 1369: 1366: 1363: 1360: 1357: 1354: 1352: 1349: 1348: 1344: 1341: 1338: 1335: 1332: 1329: 1327: 1324: 1323: 1319: 1316: 1313: 1310: 1307: 1304: 1302: 1299: 1298: 1294: 1291: 1288: 1285: 1282: 1279: 1277: 1274: 1273: 1269: 1266: 1263: 1260: 1257: 1254: 1252: 1249: 1248: 1244: 1241: 1238: 1235: 1232: 1229: 1227: 1224: 1221: 1220: 1217: 1215: 1211: 1208: 1204: 1199: 1197: 1193: 1189: 1181: 1176: 1174: 1172: 1169: 1165: 1161: 1157: 1148: 1146: 1144: 1140: 1136: 1132: 1128: 1124: 1120: 1111: 1104: 1099: 1093: 1089: 1087: 1083: 1079: 1075: 1068: 1063: 1056: 1054: 1052: 1048: 1044: 1040: 1036: 1035: 1030: 1023: 1021: 1018: 1014: 1010: 1007: 1003: 999: 995: 988: 983: 976: 971: 969: 965: 963: 962:Down Syndrome 959: 955: 948: 946: 944: 940: 936: 932: 928: 925: 921: 917: 905: 900: 896: 892: 889: 885: 878: 876: 873: 869: 865: 861: 858: 854: 850: 843: 841: 835: 831: 828: 822: 820: 814: 810: 807: 803: 796: 794: 788: 784: 781: 775: 773: 769: 763: 759: 756: 754:RefSeq (mRNA) 752: 745: 744: 739: 735: 732: 726: 725: 720: 716: 713: 711: 707: 700: 699: 694: 690: 687: 681: 680: 675: 671: 668: 666: 662: 655: 654: 649: 645: 642: 636: 635: 630: 626: 623: 621: 617: 614: 611: 609: 606: 602: 599: 595: 591: 584: 580: 575: 569: 566: 565: 563: 560: 559: 553: 550: 548: 545: 543: 540: 539: 537: 534: 533: 527: 524: 523: 521: 518: 517: 514: 513:Gene ontology 510: 506: 494: 489: 486: 484: 480: 472: 467: 456: 452: 448: 444: 440: 436: 432: 428: 424: 420: 419: 416: 412: 407: 404: 395:hair follicle 394: 390: 386: 383:skin of thigh 382: 378: 374: 370: 366: 362: 358: 357: 354: 350: 345: 342: 341: 338: 336: 332: 330: 329: 325: 324: 321: 319: 315: 311: 307: 303: 295: 290: 286: 282: 277: 267: 263: 256: 249: 243: 236: 228: 224: 220: 215: 211: 206: 202: 194: 189: 185: 181: 176: 166: 162: 155: 148: 142: 135: 131: 125: 121: 117: 112: 108: 103: 99: 95: 91: 87: 83: 79: 75: 71: 67: 63: 59: 51: 46: 39: 34: 29: 25: 20: 2434:. Retrieved 2425: 2413:. Retrieved 2404: 2392:. Retrieved 2383: 2371:. Retrieved 2362: 2348: 2336:. Retrieved 2327: 2313: 2301:. Retrieved 2292: 2280:. Retrieved 2271: 2259:. Retrieved 2250: 2238:. Retrieved 2229: 2215: 2207:"NCBI BLAST" 2201: 2166: 2162: 2152: 2140:. Retrieved 2131: 2119:. Retrieved 2110: 2096: 2084:. Retrieved 2073: 2061:. Retrieved 2057:the original 2036: 2032: 2022: 2010:. Retrieved 2001: 1989:. Retrieved 1985:the original 1956:. Retrieved 1932:. Retrieved 1928:the original 1918: 1906:. Retrieved 1897: 1885:. Retrieved 1861:. Retrieved 1799:(6): 560–5. 1796: 1792: 1786: 1774:. Retrieved 1752: 1748: 1698: 1694: 1669:. Retrieved 1660: 1648:. Retrieved 1621: 1612: 1603: 1594: 1536: 1532: 1530: 1411:NP_001135552 1326:Mus musculus 1280:Common Chimp 1251:Homo sapiens 1209: 1200: 1185: 1177:Conservation 1159: 1152: 1142: 1116: 1085: 1073: 1072: 1066: 1050: 1032: 1028: 1027: 1016: 1002:chromosome 2 993: 992: 986: 966: 953: 952: 938: 923: 915: 914: 837: 816: 790: 765: 741: 722: 696: 677: 651: 632: 612: 607: 333: 326: 53:External IDs 2221:"Time Tree" 1924:"Genomatix" 1859:. Genomatix 1857:"El Dorado" 1486:NP_611073.2 1461:NP_498059.2 1426:Danio rerio 1336:NP_061360.2 1286:XP_515638.2 1261:NP_056163.1 1156:text mining 1129:of 205,100 1088:homepage. 1078:lymph nodes 1065:Example of 1039:pseudogenes 457:Paneth cell 421:human fetus 379:skin of hip 292:36,982,747 279:36,831,272 191:97,995,948 178:97,756,333 31:Identifiers 1695:PLOS Genet 1666:"DUF 3651" 1589:, May 2017 1568:, May 2017 1545:References 1430:Zebra Fish 1301:Bos taurus 1119:amino acid 445:left colon 337:(ortholog) 74:HomoloGene 2082:. NetPhos 2078:Blom, N. 1480:Fruit Fly 1311:XP_613474 1188:orthologs 1182:Orthologs 1017:El Dorado 1006:base pair 987:El Dorado 840:NP_061360 819:NP_056163 793:NM_018872 772:NM_018497 768:NM_015348 598:Orthologs 82:GeneCards 2451:Category 2436:17 April 2415:28 April 2394:28 April 2373:28 April 2338:28 April 2303:28 April 2282:17 April 2261:17 April 2240:17 April 2193:12824352 2053:10600390 2012:29 April 1991:15 April 1908:28 April 1887:28 April 1821:32617869 1813:18616733 1776:28 April 1771:17579063 1727:21124956 1671:28 April 1650:15 April 1585:– 1564:– 1538:KIAA0922 1533:TMEM131L 1455:Nematode 1420:TMEM131 1395:TMEM131 1370:TMEM131 1345:TMEM131 1320:TMEM131 1295:TMEM131 1270:TMEM131 1196:homologs 977:Overview 888:Wikidata 577:Sources: 542:membrane 1842:. NCBI. 1718:2987931 1587:Ensembl 1566:Ensembl 1527:Paralog 1495:CG8370 1380:Chicken 1355:Opossum 1226:Species 1205:as the 1192:primate 1173:study. 1143:NetPhos 1131:daltons 1100:Protein 1086:in situ 1074:TMEM131 1067:in situ 1051:TMEM131 1029:TMEM131 994:TMEM131 954:TMEM131 939:TMEM131 924:TMEM131 920:protein 710:UniProt 665:Ensembl 604:Species 583:QuickGO 391:pylorus 312:pattern 86:TMEM131 70:1927110 45:TMEM131 38:Aliases 22:TMEM131 2191:  2184:168907 2181:  2051:  1819:  1811:  1769:  1725:  1715:  1305:Cattle 1255:Humans 1212:using 1203:Humans 1082:uterus 935:T cell 874:search 872:PubMed 743:O70472 724:Q92545 620:Entrez 483:BioGPS 170:2q11.2 62:615659 2142:5 May 2121:5 May 2086:5 May 2063:5 May 1958:4 May 1934:5 May 1863:5 May 1817:S2CID 1514:21.2% 1508:856.0 1489:24.0% 1483:725.5 1464:24.1% 1458:274.8 1439:59.6% 1433:436.8 1414:70.3% 1408:359.0 1389:76.3% 1383:323.0 1364:81.3% 1358:170.0 1339:89.7% 1330:Mouse 1314:92.1% 1289:99.6% 1223:Genus 1214:BLAST 1168:yeast 1043:locus 1034:ZAP70 1013:exons 1000:) of 998:Sense 989:tool. 653:56030 634:23505 613:Mouse 608:Human 579:Amigo 371:tibia 335:Mouse 328:Human 275:Start 210:Mouse 174:Start 107:Human 78:32428 2438:2012 2417:2012 2396:2012 2375:2012 2340:2012 2305:2012 2284:2012 2263:2012 2242:2012 2189:PMID 2144:2012 2123:2012 2088:2012 2065:2012 2049:PMID 2014:2012 1993:2012 1960:2012 1936:2012 1910:2012 1889:2012 1865:2012 1809:PMID 1778:2012 1767:PMID 1723:PMID 1673:2012 1652:2012 1517:1781 1492:1567 1467:1831 1442:1799 1417:1877 1405:Frog 1392:1821 1367:1840 1342:1877 1333:94.5 1317:1876 1308:96.6 1292:1883 1267:1883 1264:100% 1164:SOD2 1045:. A 1009:mRNA 972:Gene 927:gene 318:Bgee 266:Band 227:Chr. 165:Band 124:Chr. 58:OMIM 2179:PMC 2171:doi 2041:doi 2037:294 1801:doi 1757:doi 1753:179 1713:PMC 1703:doi 1535:or 1283:6.2 1137:or 491:n/a 288:End 187:End 90:OMA 66:MGI 2453:: 2187:. 2177:. 2167:31 2165:. 2161:. 2047:. 2035:. 2031:. 1968:^ 1944:^ 1873:^ 1848:^ 1829:^ 1815:. 1807:. 1797:74 1795:. 1765:. 1751:. 1747:. 1735:^ 1721:. 1711:. 1697:. 1693:. 1681:^ 1630:^ 1620:. 1602:. 1573:^ 1552:^ 1258:-- 1198:. 1080:, 581:/ 294:bp 281:bp 193:bp 180:bp 88:; 84:: 80:; 76:: 72:; 68:: 64:; 60:: 2440:. 2419:. 2398:. 2377:. 2356:. 2342:. 2321:. 2307:. 2286:. 2265:. 2244:. 2223:. 2209:. 2195:. 2173:: 2146:. 2125:. 2104:. 2090:. 2067:. 2043:: 2016:. 1995:. 1962:. 1938:. 1912:. 1891:. 1867:. 1823:. 1803:: 1780:. 1759:: 1729:. 1705:: 1699:6 1675:. 1654:. 1624:. 1606:. 1162:( 212:) 109:) 92::

Index

Aliases
TMEM131
OMIM
615659
MGI
1927110
HomoloGene
32428
GeneCards
TMEM131
OMA
TMEM131 - orthologs
Human
Chromosome 2 (human)
Chr.
Chromosome 2 (human)
Chromosome 2 (human)
Genomic location for TMEM131
Genomic location for TMEM131
Band
bp
bp
Mouse
Chromosome 1 (mouse)
Chr.
Chromosome 1 (mouse)
Genomic location for TMEM131
Genomic location for TMEM131
Band
bp

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