94:
1497:
1485:
158:
110:
134:
126:
118:
102:
1545:
1558:
1695:
62:, and is an integral component of cellular membranes. Transmembrane protein 151A has three transmembrane domains. The N-terminus of the protein is located in the cytosol and the C-terminus is located in the extracellular matrix. According to Compute pI, this protein has a molecular weight of approximately 51 kDa, which is the same molecular weight provided by NCBI protein.
166:
1215:
The TMEM151A promoter region consists of 1101 base pairs and it is directly adjacent to the base pairs which code for the first amino acid of the TMEM151A protein. Thousands of transcription factors were predicted to bind on this promoter region. Of those, 20 transcription factors are listed in the
1698:
This table shows a list of TMEM151 orthologues in 28 species. The table demonstrates whether TMEM151A or TMEM151B is found in the animal, the name of the species as well as its clade, the percent identity of the orthologue to humans, how many millions of years ago the species diverged from humans,
1516:
Immunohistochemistry demonstrates that TMEM151A RNA is primarily expressed in the brain (specifically the hippocampus, caudate, cerebellum, and pituitary gland), and has low levels of expression in the stomach, adipose tissue, retina, gallbladder, testes, colon, heart muscle, pancreas, salivary
2906:
Sklar, P.; Ripke, S.; Scott, L. J.; Andreassen, O. A.; Cichon, S.; Craddock, N.; Edenberg, H. J.; Nurnberger, J. I.; Rietschel, M.; Blackwood, D.; Corvin, A.; Flickinger, M.; Guan, W.; Mattingsdal, M.; McQuillin, A.; Kwan, P.; Wienker, T. F.; Daly, M.; Dudbridge, F.; Holmans, P. A.; Lin, D.;
1565:
Transmembrane protein 151A has one paralogue: TMEM151B which has a 50.76% identity with TMEM151A. It is hypothesized that TMEM151A first arose as a gene duplicate of TMEM151B approximately 320 Million Years Ago in reptiles. TMEM151A is evolving at approximately the same rate as
Hemoglobin B.
1536:
TMEM151a DNA has increased levels of expression in the heart, and has lower levels of expressions in multiple other tissues. Results from the Allen Brain Atlas demonstrate that the mouse isocortex has increased levels of in situ hybridization with TMEM151A. Microarray analysis of
1853:
p < 0.05. An unspecified variant of TMEM151A is one of 27 genes (out of 47,296 rare exonic variants that were analyzed) that has been associated with major depression disorder in
Mexican Americans. These Mexican Americans experienced hyperactivation of the
2888:
260:, 2 palmoylation sites, many phosphorylation sites, 1 signal peptide, 1 arginine and lysine cleavage site, and multiple O-BetaGlcNac sites. The table below lists predicted post translational modifications for TMEM151A in several species.
176:, the grey represents transmembrane domains, the blue circles represent extracellular regions. The red diamonds represent the locations of amino acids that are conserved in all 28 species tested. The blue line represents the predicted
1624:. TMEM151A was not present in any bird species. This suggests that TMEM151A evolved via gene duplication approximately 320 million years ago, as reptiles do have both TMEM151A and TMEM151B, but birds only have TMEM151A.
1858:
due to significant stress. Transplanted livers that came from deceased donors had a 4.83-fold upregulated expression of TMEM151A when compared to the expression levels of TMEM151A in livers that came from live donors.
1760:– May localize in the mitochondrion or plasma membrane. It is primarily expressed in the circulatory (blood, lymph node, cardiac cells) and nervous system (brain, cortex, cerebellum, spinal cord, tibial nerve).
1776:– this encodes the queosine salvage protein (the function of which is not well understood). Expression of this gene is highest in the duodenum and small intestine, it is a member of the DUF 2419 family.
1569:
It appears as though TMEM151 is conserved in most if not all vertebrates, and is conserved in many invertebrates (except for
Porifera and Cnidaria). The details of this conclusion are listed below:
208:, and lysine than would be expected for an average protein. The internal compositional analysis of all the individual segments of the protein (ex. transmembrane domain 1, intermembrane space,
1524:
TMEM151a DNA is found at relatively higher levels in the heart and the brain (specifically the frontal and occipital cortexes), and has lower levels of expression in multiple other tissues.
145:
of the protein is predicted to consist of approximately alpha helices and beta sheets (the exact location and number of which depend on the program which is used for the prediction) but no
1818:– is associated with diseases: Meckel syndrome, type 6 and type 1. It is located on chromosome 16 and is predicted to localize in the nucleus, cytosol, and most likely in the cytoskeleton.
1683:
in BLAST; however, TMEM151B was found in BLAT for lampreys. This suggests that TMEM151B is likely found in many cartilaginous fishes; it is simply not recorded. TMEM151B could
78:
1 is smaller and more acidic than exon 2. Transmembrane domain 2 is acidic, although it is located in exon 2 which averages to be basic. TMEM151A has no known
42:
The gene encoding transmembrane protein 151A is located on the positive strand of chromosome 11q13.2 and has two exons. The gene consists of a total of 2538
2143:
2907:
Burmeister, M.; Greenwood, T. A.; Hamshere, M. L.; Muglia, P.; Smith, E. N.; Zandi, P. P.; Nievergelt, C. M.; McKinney, R.; et al. (September 2012).
1824:– is located on chromosome 17 and is crucial for heart development and aids in the specification of lineage commitment of cardiomyocyte development
2052:
2823:
1796:– stands for sterile alpha motif domain containing protein 10. It is located on chromosome 20. Diseases associated with this gene include
1973:
1517:
gland; a polyclonal rabbit TMEM151A antibody from Sigma
Aldrich was used to get these results. These results were listed as “uncertain.”
2168:
1925:
1855:
1833:
Illumina analysis has demonstrated that TMEM151A is one of 336 genes that may be used, in combination with the other genes, to diagnose
814:, mammals, lancelets, and some invertebrates. It is predicted to localize in the nucleus for birds and other invertebrates (Table 1).
93:
1812:– Sosondowah Ankyrin repeat domain family member D. It is located on chromosome X and predicted to localize in the mitochondrion.
1647:. This absence in amphibians may be due to (1) a lack of records or (2) genetic divergence. TMEM151B is present in several
97:
Tertiary structure TMEM151A as predicted by Swiss Model. The arrows represent beta sheets and the coils represent alpha helices.
3068:
1496:
1484:
67:
3023:"Gene Expression Profile in Liver Transplantation and the Influence of Gene Dysregulation Occurring in Deceased Donor Grafts"
2909:"Erratum: Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4"
2771:
2701:
1216:
table below. Many transcription factors predicted to bind to the promoter region were related to the following categories:
220:
than would be expected for an average protein in the c-terminus. TMEM151A composition is highly conserved between mammals.
66:
demonstrates that TMEM151A has a molecular weight of approximately 55 kDa which suggests that the protein may undergo
2662:
2607:
2552:
2440:
2408:
2365:
2312:
2204:
2530:
2291:
2964:
Wong, M-L; Arcos-Burgos, M; Liu, S; Vélez, J I; Yu, C; Baune, B T; Jawahar, M C; Arolt, V; Dannlowski, U (2016-10-25).
2837:
2470:
2233:
2030:
2500:
2262:
1782:– is a protein encoding gene of unknown function. It is associated with neural tube defects and folate sensitivity.
87:
1763:
2743:
2640:
2387:
2147:
157:
2757:
2081:
1223:
109:
2729:
847:
294:
1644:
1640:
807:
257:
2585:
2344:
1561:
Transmembrane protein 151A rate of evolution in comparison to cytochrome C, fibrinogen, and hemoglobin.
133:
125:
1797:
1668:
2866:
248:
sites in the N-terminus whereas non vertebrates (capitella teleta and water bear) instead have more
1845:
circulating in the blood during colorectal cancer. TMEM151A is in linkage disequilibrium with gene
142:
117:
1768:-is located on chromosome 14, and or 90. It is predicted to localize in the mitochondria membrane
1320:(likely involved in nuclear control of mitochondrial function and cytochrome oxidase expression)
2119:
1994:
1965:
3044:
3003:
2985:
2946:
2928:
2829:
2819:
1917:
1834:
1656:
101:
71:
1707:, but it was found in one lancelet. As TMEM151B was found in lancelets, TMEM151B is found in
3034:
2993:
2977:
2936:
2920:
1850:
1806:– is located on chromosome 15 and is predicted to localize in the peroxisome and/or cytosol.
1613:
1557:
856:
303:
1694:
1544:
149:. Diagrams of the predicted tertiary structure and transmembrane domains are to the right.
249:
252:
sites instead (and one n-myrstyolation site) in the N-terminus. TMEM151A in humans has 3
1790:– is a human cervical cancer suppressor gene. It has RNA polymerase II specific activity
105:
Predicted tertiary structure of TMEM151A with hydrophobic elements highlighted in green.
2998:
2966:"The PHF21B gene is associated with major depression and modulates the stress response"
2965:
2941:
2908:
245:
177:
3062:
2095:
1708:
1609:
1597:
838:
63:
59:
1947:
212:, etc.) all had amino acid abundances that fell into expected ranges except for the
1688:
1664:
1660:
1628:
1621:
1593:
1585:
828:
278:
233:
3039:
3022:
2182:
1881:
1652:
1617:
1605:
1229:
146:
43:
2432:
2196:
1838:
1736:
1732:
1581:
1285:
Huntington's disease gene regulatory region binding proteins (more downstream
864:
311:
213:
209:
205:
201:
197:
55:
3048:
2989:
2932:
2833:
2522:
2283:
1453:
Huntington's disease gene regulatory region binding proteins (most upstream)
1296:
Huntington's disease gene regulatory region binding proteins (more upstream)
1842:
1704:
1648:
1636:
1600:. TMEM151A and TMEM151B were present in the following reptile orders:
1589:
253:
83:
3007:
2950:
2813:
2687:
2462:
2225:
2018:
216:. Specifically, there is less asparagine, isoleucine, and lysine and more
172:. The green spaces represent regions of the protein that are found in the
2924:
2493:"GPS-SUMO: Prediction of SUMOylation Sites & SUMO-interaction Motifs"
2492:
2255:"GPS-SUMO: Prediction of SUMOylation Sites & SUMO-interaction Motifs"
2254:
1837:
and/or the stage of that cancer. Specifically, TMEM151A is significantly
1728:
1724:
1720:
1716:
1712:
1680:
1676:
1601:
1577:
1573:
1239:
1235:
241:
217:
2981:
1541:
shows that TMEM151a DNA increased in both the cerebrum and the pancreas.
1475:
Krueppel-associated box-containing zinc-finger protein 57 (KRAB-ZFP 57)
17:
2799:
1846:
1785:
1772:
1632:
1572:
TMEM151A and TMEM151B are conserved in all of the major mammal orders:
286:
237:
189:
185:
173:
79:
2632:
2379:
1750:
193:
165:
46:, 1407 of which encode for the amino acids of the final transcript.
1966:"Tissue expression of TMEM151A – Summary – The Human Protein Atlas"
1693:
1608:. TMEM151B (only) was found in many extant bird orders including:
1556:
1543:
1495:
1483:
164:
132:
124:
116:
108:
100:
92:
1753:, TMEM151A is predicted to interact with the following proteins:
2715:
1508:
Five different promoters influence the expression of this gene.
1420:
EGR/nerve growth factor induced protein C & related factors
75:
1206:
Table 1: Predicted localization of TMEM151 in various species
2577:
2336:
113:
TMEM151A transmembrane domains visualized as helical wheels
2785:
2858:
1800:. It is predicted to localize in the nucleus/nucleoplasm.
1995:"Anti-TMEM151A antibody produced in rabbit HPA041035"
1631:. TMEM151B could not be found in the amphibian order
34:, is a protein that is encoded by the TMEM151A gene.
1849:; CACNA1C mutation is significantly associated with
1464:
Leucine rich repeat (in FLII) interacting protein 1
1387:Pleomorphic adenoma gene 1 (salivary gland tumor)
2859:"STRING: functional protein association networks"
2096:"NPS@ : GOR4 secondary structure prediction"
806:TMEM151A protein is predicted to localize in the
616:Prediction of arginine and lysine cleavage sites
1912:
1910:
1908:
1906:
1699:and the NCBI accession code for the orthologue.
1663:. It could not be found in the bony fish order
1318:GA binding protein transcription factor, alpha
2053:"Gene: TMEM151A (ENSG00000179292) – Summary –
1398:Glial cells (nerve support) missing homolog 1
184:The most abundant amino acids in TMEM151A are
82:, and is a part of family pfam15857 with one
8:
2433:"CSS-Palm – Palmitoylation Site Prediction"
2197:"CSS-Palm – Palmitoylation Site Prediction"
1627:TMEM151B is present in the amphibian order
579:Another prediction of transmembrane regions
2019:"TMEM151A transmembrane protein 151A [
3038:
2997:
2940:
1876:
1874:
1872:
129:TMEM151A Annotated Translation C-Terminus
74:of the whole protein is approximately 8.
2730:"NCBI Unigene Transmembrane Protein151A"
1245:
816:
262:
156:
1868:
1520:Unigene microarray analysis shows that
1532:Microarray analysis demonstrates that
1354:Nerve growth factor induced protein C
121:TMEM151A Annotated Protein N-Terminus
2503:from the original on 17 February 2019
1196:
1191:
1186:
1181:
1176:
1171:
1166:
1159:
1154:
1149:
1144:
1139:
1134:
1129:
1122:
1117:
1112:
1107:
1102:
1097:
1092:
1085:
1080:
1075:
1070:
1065:
1060:
1055:
1048:
1043:
1038:
1033:
1028:
1023:
1018:
1011:
1006:
1001:
996:
991:
986:
981:
974:
969:
967:
962:
957:
952:
947:
940:
935:
930:
925:
920:
915:
910:
903:
898:
893:
888:
883:
878:
873:
862:
853:
844:
835:
826:
821:
819:
7:
2473:from the original on 5 February 2018
1928:from the original on 26 October 2017
1671:, specifically sharks. TMEM151B was
1528:TMEM151A expression in other animals
1274:KRAB containing zinc finger protein
2533:from the original on 2 January 2019
1856:hypothalamic-pituitary-adrenal axis
1431:KRAB domain zinc finger protein 57
1332:ZF5 POZ domain zinc finger protein
54:Transmembrane protein 151A has 468
2758:"TMEM151A Allen Mouse Brain Atlas"
2663:"5CBABD7D0000393B3A8B36C4 expired"
2608:"5CBAB33C00002F5C22ED82DB expired"
2588:from the original on 27 April 2019
2553:"5CBA9F710000143B6B879311 expired"
2313:"5CBA9F710000143B6B879311 expired"
2033:from the original on 15 April 2016
1719:. TMEM151B is also found in
1343:ZF1-myeloid zinc finger 1 protein
137:TMEM151A annotated translation key
25:
2643:from the original on 2 April 2019
2443:from the original on 20 July 2018
1882:"transmembrane protein 151A [
1252:Transcription factor description
2889:"Monocyte Cancer Biomarker 2013"
1409:Androgene receptor binding site
1263:cAMP-responsive binding element
68:post-translational modifications
2869:from the original on 2019-04-26
2840:from the original on 2019-03-18
2390:from the original on 2019-04-02
2347:from the original on 2019-04-27
2294:from the original on 2019-01-02
2265:from the original on 2019-02-17
2236:from the original on 2018-02-05
2207:from the original on 2018-07-20
1976:from the original on 2015-11-05
1703:TMEM151B could not be found in
161:TMEM151A amino acid composition
2716:"TMEM151A Human Protein Atlas"
2183:"N-Myristylation Sites ExPasy"
1504:microarray expression GDS 3113
1492:microarray expression GDS 3113
1307:EGR1, early growth response 1
764:O-beta glcnac attachment sites
153:Protein compositional analysis
1:
1948:"Compute PI/Molecular Weight"
1512:TMEM151A expression in humans
2057:– Ensembl genome browser 96"
204:. There is less asparagine,
3040:10.2174/1874300501105010001
2772:"TMEM151A GDS4164 NCBI NIH"
2124:zhanglab.ccmb.med.umich.edu
2023:(human)] – Gene – NCBI"
1635:(newts and salamanders) or
1442:Estrogen related receptors
1376:GATA-GATA binding factor 1
727:TMHMM transmembrane regions
3085:
3021:Conti, Anna (2011-02-10).
2633:"ExPASy – Sulfinator tool"
2380:"ExPASy – Sulfinator tool"
28:Transmembrane protein 151A
1691:in either BLAST or BLAT.
1667:. TMEM151B is present in
1548:Orthologue space TMEM151A
1220:Neural and growth related
949:Secretory system vesicles
866:Ramazzottius varieornatus
653:Signal peptide prediction
312:Ramazzottius varieornatus
192:. The least abundant are
3027:The Open Surgery Journal
224:Protein level regulation
2523:"NetGlycate 1.0 Server"
2284:"NetGlycate 1.0 Server"
2144:"Helical Wheel Rutgers"
1886:] – Protein – NCBI"
1639:(caecilians) in either
830:Ursus arctos horribilis
279:Ursus arctos horribilis
267:Number of modifications
232:and other vertebrates (
3069:Transmembrane proteins
2744:"TMEM151A GDS3052 GEO"
1700:
1562:
1553:Homology and evolution
1549:
1539:Canis lupus familiaris
1505:
1493:
848:Branchiostoma floridae
505:Nuclear export signals
394:Phosphorylation sites*
295:Branchiostoma floridae
181:
162:
138:
130:
122:
114:
106:
98:
2893:United States Patents
2887:Mazzone; et al.
2702:"TMEM151A Genomatrix"
2463:"DAS-TMfilter server"
2437:csspalm.biocuckoo.org
2226:"DAS-TMfilter server"
2201:csspalm.biocuckoo.org
1918:"Gene Cards TMEM151A"
1697:
1645:BLAT (bioinformatics)
1560:
1547:
1499:
1487:
1211:Gene level regulation
875:Endoplasmic reticulum
808:endoplasmic reticulum
802:Cellular localization
542:Phosphorylation sites
357:Transmembrane regions
258:nuclear export signal
256:sites, it may have a
168:
160:
136:
128:
120:
112:
104:
96:
2970:Molecular Psychiatry
2925:10.1038/ng0912-1072a
2497:sumosp.biocuckoo.org
2259:sumosp.biocuckoo.org
2027:www.ncbi.nlm.nih.gov
1970:www.proteinatlas.org
1890:www.ncbi.nlm.nih.gov
1798:retinitis pigmentosa
1745:Protein interactions
1669:cartilaginous fishes
1365:Estrogen Receptor 2
690:Sulfinated tyrosines
2982:10.1038/mp.2016.174
1711:, but not found in
143:secondary structure
2120:"I-TASSER results"
2100:npsa-prabi.ibcp.fr
2061:uswest.ensembl.org
1829:Research in humans
1701:
1651:orders including:
1563:
1550:
1506:
1494:
1255:Matrix similarity
320:Palmoylation sites
182:
170:TMEM151A animation
163:
139:
131:
123:
115:
107:
99:
70:. The theoretical
2825:978-1-4493-5811-2
2582:phobius.sbc.su.se
2341:phobius.sbc.su.se
1835:colorectal cancer
1657:tetraodontiformes
1482:
1481:
1203:
1202:
799:
798:
16:(Redirected from
3076:
3053:
3052:
3042:
3018:
3012:
3011:
3001:
2976:(7): 1015–1025.
2961:
2955:
2954:
2944:
2903:
2897:
2896:
2884:
2878:
2877:
2875:
2874:
2855:
2849:
2848:
2846:
2845:
2810:
2804:
2803:
2796:
2790:
2789:
2782:
2776:
2775:
2768:
2762:
2761:
2754:
2748:
2747:
2740:
2734:
2733:
2726:
2720:
2719:
2712:
2706:
2705:
2698:
2692:
2691:
2684:
2678:
2677:
2675:
2673:
2659:
2653:
2652:
2650:
2648:
2629:
2623:
2622:
2620:
2618:
2604:
2598:
2597:
2595:
2593:
2574:
2568:
2567:
2565:
2563:
2549:
2543:
2542:
2540:
2538:
2519:
2513:
2512:
2510:
2508:
2489:
2483:
2482:
2480:
2478:
2467:mendel.imp.ac.at
2459:
2453:
2452:
2450:
2448:
2429:
2423:
2422:
2420:
2419:
2405:
2399:
2398:
2396:
2395:
2376:
2370:
2369:
2362:
2356:
2355:
2353:
2352:
2333:
2327:
2326:
2324:
2323:
2309:
2303:
2302:
2300:
2299:
2280:
2274:
2273:
2271:
2270:
2251:
2245:
2244:
2242:
2241:
2230:mendel.imp.ac.at
2222:
2216:
2215:
2213:
2212:
2193:
2187:
2186:
2179:
2173:
2172:
2165:
2159:
2158:
2156:
2155:
2146:. Archived from
2140:
2134:
2133:
2131:
2130:
2116:
2110:
2109:
2107:
2106:
2092:
2086:
2085:
2078:
2072:
2071:
2069:
2067:
2049:
2043:
2042:
2040:
2038:
2015:
2009:
2008:
2006:
2005:
1991:
1985:
1984:
1982:
1981:
1962:
1956:
1955:
1944:
1938:
1937:
1935:
1933:
1914:
1901:
1900:
1898:
1896:
1878:
1851:bipolar disorder
1614:Caprimulgiformes
1246:
857:Capitella teleta
817:
468:Net glycation **
431:Sumo-interaction
304:Capitella teleta
263:
246:N-myristoylation
58:, weighs 51,278
30:, also known as
21:
3084:
3083:
3079:
3078:
3077:
3075:
3074:
3073:
3059:
3058:
3057:
3056:
3020:
3019:
3015:
2963:
2962:
2958:
2913:Nature Genetics
2905:
2904:
2900:
2886:
2885:
2881:
2872:
2870:
2857:
2856:
2852:
2843:
2841:
2826:
2812:
2811:
2807:
2798:
2797:
2793:
2784:
2783:
2779:
2770:
2769:
2765:
2756:
2755:
2751:
2742:
2741:
2737:
2728:
2727:
2723:
2714:
2713:
2709:
2700:
2699:
2695:
2686:
2685:
2681:
2671:
2669:
2661:
2660:
2656:
2646:
2644:
2631:
2630:
2626:
2616:
2614:
2606:
2605:
2601:
2591:
2589:
2576:
2575:
2571:
2561:
2559:
2551:
2550:
2546:
2536:
2534:
2521:
2520:
2516:
2506:
2504:
2491:
2490:
2486:
2476:
2474:
2461:
2460:
2456:
2446:
2444:
2431:
2430:
2426:
2417:
2415:
2407:
2406:
2402:
2393:
2391:
2378:
2377:
2373:
2364:
2363:
2359:
2350:
2348:
2335:
2334:
2330:
2321:
2319:
2311:
2310:
2306:
2297:
2295:
2282:
2281:
2277:
2268:
2266:
2253:
2252:
2248:
2239:
2237:
2224:
2223:
2219:
2210:
2208:
2195:
2194:
2190:
2181:
2180:
2176:
2167:
2166:
2162:
2153:
2151:
2142:
2141:
2137:
2128:
2126:
2118:
2117:
2113:
2104:
2102:
2094:
2093:
2089:
2080:
2079:
2075:
2065:
2063:
2051:
2050:
2046:
2036:
2034:
2017:
2016:
2012:
2003:
2001:
1993:
1992:
1988:
1979:
1977:
1964:
1963:
1959:
1946:
1945:
1941:
1931:
1929:
1916:
1915:
1904:
1894:
1892:
1880:
1879:
1870:
1865:
1831:
1747:
1555:
1530:
1514:
1213:
983:Plasma membrane
804:
250:phosphorylation
226:
155:
52:
40:
23:
22:
15:
12:
11:
5:
3082:
3080:
3072:
3071:
3061:
3060:
3055:
3054:
3013:
2956:
2919:(9): 977–983.
2898:
2879:
2850:
2824:
2805:
2791:
2777:
2763:
2749:
2735:
2721:
2707:
2693:
2679:
2667:www.cbs.dtu.dk
2654:
2637:web.expasy.org
2624:
2612:www.cbs.dtu.dk
2599:
2569:
2557:www.cbs.dtu.dk
2544:
2527:www.cbs.dtu.dk
2514:
2484:
2454:
2424:
2413:www.cbs.dtu.dk
2400:
2384:web.expasy.org
2371:
2357:
2328:
2317:www.cbs.dtu.dk
2304:
2288:www.cbs.dtu.dk
2275:
2246:
2217:
2188:
2174:
2160:
2135:
2111:
2087:
2073:
2044:
2010:
1986:
1957:
1939:
1902:
1867:
1866:
1864:
1861:
1830:
1827:
1826:
1825:
1819:
1813:
1807:
1801:
1791:
1783:
1777:
1769:
1761:
1746:
1743:
1584:, Chiropetra,
1554:
1551:
1529:
1526:
1513:
1510:
1480:
1479:
1476:
1473:
1469:
1468:
1465:
1462:
1458:
1457:
1454:
1451:
1447:
1446:
1443:
1440:
1436:
1435:
1432:
1429:
1425:
1424:
1421:
1418:
1414:
1413:
1410:
1407:
1403:
1402:
1399:
1396:
1392:
1391:
1388:
1385:
1381:
1380:
1377:
1374:
1370:
1369:
1366:
1363:
1359:
1358:
1355:
1352:
1348:
1347:
1344:
1341:
1337:
1336:
1333:
1330:
1326:
1325:
1322:
1316:
1312:
1311:
1308:
1305:
1301:
1300:
1297:
1294:
1290:
1289:
1286:
1283:
1279:
1278:
1275:
1272:
1268:
1267:
1264:
1261:
1257:
1256:
1253:
1250:
1244:
1243:
1232:
1226:
1221:
1212:
1209:
1201:
1200:
1195:
1190:
1185:
1180:
1175:
1170:
1164:
1163:
1158:
1153:
1148:
1143:
1138:
1133:
1127:
1126:
1121:
1116:
1111:
1106:
1101:
1096:
1090:
1089:
1084:
1079:
1074:
1069:
1064:
1059:
1053:
1052:
1047:
1042:
1037:
1032:
1027:
1022:
1016:
1015:
1010:
1005:
1000:
995:
990:
985:
979:
978:
973:
968:
966:
961:
956:
951:
945:
944:
939:
934:
929:
924:
919:
914:
908:
907:
902:
897:
892:
887:
882:
877:
871:
870:
861:
852:
843:
834:
825:
820:
803:
800:
797:
796:
791:
786:
781:
776:
771:
766:
760:
759:
754:
749:
744:
739:
734:
729:
723:
722:
717:
712:
707:
702:
697:
692:
686:
685:
680:
675:
670:
665:
660:
655:
649:
648:
643:
638:
633:
628:
623:
618:
612:
611:
606:
601:
596:
591:
586:
581:
575:
574:
569:
564:
559:
554:
549:
544:
538:
537:
532:
527:
522:
517:
512:
507:
501:
500:
495:
490:
485:
480:
475:
470:
464:
463:
458:
453:
448:
443:
438:
433:
427:
426:
421:
416:
411:
406:
401:
396:
390:
389:
384:
379:
374:
369:
364:
359:
353:
352:
347:
342:
337:
332:
327:
322:
316:
315:
308:
299:
290:
283:
274:
269:
225:
222:
178:signal peptide
154:
151:
51:
48:
39:
36:
24:
14:
13:
10:
9:
6:
4:
3:
2:
3081:
3070:
3067:
3066:
3064:
3050:
3046:
3041:
3036:
3032:
3028:
3024:
3017:
3014:
3009:
3005:
3000:
2995:
2991:
2987:
2983:
2979:
2975:
2971:
2967:
2960:
2957:
2952:
2948:
2943:
2938:
2934:
2930:
2926:
2922:
2918:
2914:
2910:
2902:
2899:
2894:
2890:
2883:
2880:
2868:
2864:
2863:string-db.org
2860:
2854:
2851:
2839:
2835:
2831:
2827:
2821:
2817:
2816:
2809:
2806:
2801:
2795:
2792:
2787:
2781:
2778:
2773:
2767:
2764:
2759:
2753:
2750:
2745:
2739:
2736:
2731:
2725:
2722:
2717:
2711:
2708:
2703:
2697:
2694:
2689:
2683:
2680:
2668:
2664:
2658:
2655:
2642:
2638:
2634:
2628:
2625:
2613:
2609:
2603:
2600:
2587:
2583:
2579:
2573:
2570:
2558:
2554:
2548:
2545:
2532:
2528:
2524:
2518:
2515:
2502:
2498:
2494:
2488:
2485:
2472:
2468:
2464:
2458:
2455:
2442:
2438:
2434:
2428:
2425:
2414:
2410:
2404:
2401:
2389:
2385:
2381:
2375:
2372:
2367:
2361:
2358:
2346:
2342:
2338:
2332:
2329:
2318:
2314:
2308:
2305:
2293:
2289:
2285:
2279:
2276:
2264:
2260:
2256:
2250:
2247:
2235:
2231:
2227:
2221:
2218:
2206:
2202:
2198:
2192:
2189:
2184:
2178:
2175:
2170:
2164:
2161:
2150:on 2019-07-15
2149:
2145:
2139:
2136:
2125:
2121:
2115:
2112:
2101:
2097:
2091:
2088:
2083:
2077:
2074:
2062:
2058:
2056:
2048:
2045:
2032:
2028:
2024:
2022:
2014:
2011:
2000:
1999:Sigma-Aldrich
1996:
1990:
1987:
1975:
1971:
1967:
1961:
1958:
1953:
1949:
1943:
1940:
1927:
1923:
1922:genecards.org
1919:
1913:
1911:
1909:
1907:
1903:
1891:
1887:
1885:
1877:
1875:
1873:
1869:
1862:
1860:
1857:
1852:
1848:
1844:
1840:
1836:
1828:
1823:
1820:
1817:
1814:
1811:
1808:
1805:
1802:
1799:
1795:
1792:
1789:
1788:
1784:
1781:
1778:
1775:
1774:
1770:
1767:
1766:
1762:
1759:
1756:
1755:
1754:
1752:
1749:According to
1744:
1742:
1741:
1738:
1734:
1730:
1726:
1722:
1718:
1714:
1710:
1709:Echinodermata
1706:
1696:
1692:
1690:
1686:
1682:
1678:
1674:
1670:
1666:
1662:
1658:
1654:
1650:
1646:
1642:
1638:
1634:
1630:
1625:
1623:
1619:
1615:
1611:
1610:Columbiformes
1607:
1603:
1599:
1598:Diprotodontia
1595:
1591:
1587:
1583:
1579:
1575:
1570:
1567:
1559:
1552:
1546:
1542:
1540:
1535:
1527:
1525:
1523:
1518:
1511:
1509:
1503:
1498:
1491:
1486:
1477:
1474:
1471:
1470:
1466:
1463:
1460:
1459:
1455:
1452:
1449:
1448:
1444:
1441:
1438:
1437:
1433:
1430:
1427:
1426:
1422:
1419:
1416:
1415:
1411:
1408:
1405:
1404:
1400:
1397:
1394:
1393:
1389:
1386:
1383:
1382:
1378:
1375:
1372:
1371:
1367:
1364:
1361:
1360:
1356:
1353:
1350:
1349:
1345:
1342:
1339:
1338:
1334:
1331:
1328:
1327:
1323:
1321:
1317:
1314:
1313:
1309:
1306:
1303:
1302:
1298:
1295:
1292:
1291:
1287:
1284:
1281:
1280:
1276:
1273:
1270:
1269:
1265:
1262:
1259:
1258:
1254:
1251:
1248:
1247:
1241:
1237:
1233:
1231:
1227:
1225:
1222:
1219:
1218:
1217:
1210:
1208:
1207:
1199:
1194:
1189:
1184:
1179:
1174:
1169:
1165:
1162:
1157:
1152:
1147:
1142:
1137:
1132:
1128:
1125:
1120:
1115:
1110:
1105:
1100:
1095:
1094:Extracellular
1091:
1088:
1083:
1078:
1073:
1068:
1063:
1058:
1054:
1051:
1046:
1041:
1036:
1031:
1026:
1021:
1017:
1014:
1009:
1004:
999:
994:
989:
984:
980:
977:
972:
965:
960:
955:
950:
946:
943:
938:
933:
928:
923:
918:
913:
909:
906:
901:
896:
891:
886:
881:
876:
872:
869:
868:
867:
860:
859:
858:
851:
850:
849:
842:
841:
840:
839:Gallus gallus
833:
832:
831:
824:
818:
815:
813:
809:
801:
795:
792:
790:
787:
785:
782:
780:
777:
775:
772:
770:
767:
765:
762:
761:
758:
755:
753:
750:
748:
745:
743:
740:
738:
735:
733:
730:
728:
725:
724:
721:
718:
716:
713:
711:
708:
706:
703:
701:
698:
696:
693:
691:
688:
687:
684:
681:
679:
676:
674:
671:
669:
666:
664:
661:
659:
656:
654:
651:
650:
647:
644:
642:
639:
637:
634:
632:
629:
627:
624:
622:
619:
617:
614:
613:
610:
607:
605:
602:
600:
597:
595:
592:
590:
587:
585:
582:
580:
577:
576:
573:
570:
568:
565:
563:
560:
558:
555:
553:
550:
548:
545:
543:
540:
539:
536:
533:
531:
528:
526:
523:
521:
518:
516:
513:
511:
508:
506:
503:
502:
499:
496:
494:
491:
489:
486:
484:
481:
479:
476:
474:
471:
469:
466:
465:
462:
459:
457:
454:
452:
449:
447:
444:
442:
439:
437:
434:
432:
429:
428:
425:
422:
420:
417:
415:
412:
410:
407:
405:
402:
400:
397:
395:
392:
391:
388:
385:
383:
380:
378:
375:
373:
370:
368:
365:
363:
360:
358:
355:
354:
351:
348:
346:
343:
341:
338:
336:
333:
331:
328:
326:
323:
321:
318:
317:
314:
313:
309:
307:
306:
305:
300:
298:
297:
296:
291:
289:
288:
287:Gallus gallus
284:
282:
281:
280:
275:
273:
270:
268:
265:
264:
261:
259:
255:
251:
247:
243:
239:
235:
234:grizzly bears
231:
223:
221:
219:
215:
211:
207:
203:
199:
195:
191:
187:
179:
175:
171:
167:
159:
152:
150:
148:
144:
135:
127:
119:
111:
103:
95:
91:
89:
85:
81:
77:
73:
69:
65:
64:Sigma-Aldrich
61:
57:
49:
47:
45:
37:
35:
33:
29:
19:
3030:
3026:
3016:
2973:
2969:
2959:
2916:
2912:
2901:
2892:
2882:
2871:. Retrieved
2862:
2853:
2842:. Retrieved
2814:
2808:
2800:"NCBI Blast"
2794:
2780:
2766:
2752:
2738:
2724:
2710:
2696:
2682:
2670:. Retrieved
2666:
2657:
2645:. Retrieved
2636:
2627:
2615:. Retrieved
2611:
2602:
2590:. Retrieved
2581:
2572:
2560:. Retrieved
2556:
2547:
2535:. Retrieved
2526:
2517:
2505:. Retrieved
2496:
2487:
2475:. Retrieved
2466:
2457:
2445:. Retrieved
2436:
2427:
2416:. Retrieved
2412:
2403:
2392:. Retrieved
2383:
2374:
2360:
2349:. Retrieved
2340:
2331:
2320:. Retrieved
2316:
2307:
2296:. Retrieved
2287:
2278:
2267:. Retrieved
2258:
2249:
2238:. Retrieved
2229:
2220:
2209:. Retrieved
2200:
2191:
2177:
2163:
2152:. Retrieved
2148:the original
2138:
2127:. Retrieved
2123:
2114:
2103:. Retrieved
2099:
2090:
2076:
2064:. Retrieved
2060:
2055:Homo sapiens
2054:
2047:
2035:. Retrieved
2026:
2021:Homo sapiens
2020:
2013:
2002:. Retrieved
1998:
1989:
1978:. Retrieved
1969:
1960:
1951:
1942:
1930:. Retrieved
1921:
1893:. Retrieved
1889:
1884:Homo sapiens
1883:
1832:
1821:
1815:
1809:
1803:
1793:
1786:
1779:
1771:
1764:
1757:
1748:
1739:
1702:
1689:jawless fish
1687:be found in
1684:
1672:
1665:lophiiformes
1661:siluriformes
1626:
1622:Cuculiformes
1594:Soricomorpha
1586:Artiodactyla
1571:
1568:
1564:
1538:
1534:Mus musculus
1533:
1531:
1522:Homo sapiens
1521:
1519:
1515:
1507:
1502:Homo sapiens
1501:
1490:Homo sapiens
1489:
1319:
1224:Huntington's
1214:
1205:
1204:
1197:
1192:
1187:
1182:
1177:
1172:
1167:
1160:
1155:
1150:
1145:
1140:
1135:
1130:
1123:
1118:
1113:
1108:
1103:
1098:
1093:
1086:
1081:
1076:
1071:
1066:
1061:
1056:
1049:
1044:
1039:
1034:
1029:
1024:
1019:
1012:
1007:
1002:
997:
992:
987:
982:
975:
970:
963:
958:
953:
948:
941:
936:
931:
926:
921:
916:
912:Mitochondria
911:
904:
899:
894:
889:
884:
879:
874:
865:
863:
855:
854:
846:
845:
837:
836:
829:
827:
822:
812:Homo sapiens
811:
805:
793:
788:
783:
778:
773:
768:
763:
756:
751:
746:
741:
736:
731:
726:
719:
714:
709:
704:
699:
694:
689:
682:
677:
672:
667:
662:
657:
652:
645:
640:
635:
630:
625:
620:
615:
608:
603:
598:
593:
588:
583:
578:
571:
566:
561:
556:
551:
546:
541:
534:
529:
524:
519:
514:
509:
504:
497:
492:
487:
482:
477:
472:
467:
460:
455:
450:
445:
440:
435:
430:
423:
418:
413:
408:
403:
398:
393:
386:
381:
376:
371:
366:
361:
356:
349:
344:
339:
334:
329:
324:
319:
310:
302:
301:
293:
292:
285:
277:
276:
271:
266:
230:Homo sapiens
229:
228:TMEM151A in
227:
183:
169:
147:coiled coils
140:
53:
41:
31:
27:
26:
3033:(1): 1–11.
1839:upregulated
1653:perciformes
1618:Apodiformes
1606:Testudinata
1230:Zinc finger
1057:Cytoplasmic
180:cut region.
56:amino acids
44:nucleotides
2873:2019-04-21
2844:2019-04-21
2786:"TimeTree"
2688:"PSORT II"
2418:2019-04-21
2394:2019-04-21
2351:2019-04-21
2322:2019-04-21
2298:2019-04-21
2269:2019-04-21
2240:2019-04-21
2211:2019-04-21
2154:2019-05-06
2129:2019-05-05
2105:2019-05-05
2004:2019-04-21
1980:2019-04-21
1863:References
1737:Arthropoda
1733:Tardigrada
1675:found for
1582:Lagomorpha
214:c-terminus
210:n-terminus
206:isoleucine
202:asparagine
198:methionine
3049:1874-3005
2990:1359-4184
2933:1061-4036
2834:326794237
2578:"Phobius"
2337:"Phobius"
1843:monocytes
1841:in human
1705:tunicates
1649:bony fish
1590:Carnivora
1500:TMEM151A
1488:TMEM151A
1234:Steroid (
254:glycation
242:lancelets
84:paralogue
3063:Category
3008:27777418
2951:21926972
2867:Archived
2838:Archived
2672:27 April
2647:27 April
2641:Archived
2617:27 April
2592:27 April
2586:Archived
2562:27 April
2537:27 April
2531:Archived
2507:27 April
2501:Archived
2477:27 April
2471:Archived
2447:27 April
2441:Archived
2388:Archived
2345:Archived
2292:Archived
2263:Archived
2234:Archived
2205:Archived
2066:27 April
2037:27 April
2031:Archived
1974:Archived
1932:27 April
1926:Archived
1895:27 April
1780:C1orf167
1729:Nematoda
1725:Mollusca
1721:Annelida
1717:Cnidaria
1713:Porifera
1677:lampreys
1602:Squamata
1578:Rodentia
1574:Primates
1240:estrogen
1236:androgen
1131:Vacuolar
794:multiple
789:multiple
784:multiple
779:multiple
774:multiple
769:multiple
238:chickens
218:arginine
88:TMEM151B
80:isoforms
32:TMEM151A
18:TMEM151A
2999:5461220
2942:3637176
2409:"TMHMM"
2082:"JPRED"
1847:CACNA1C
1816:CCDC135
1804:ANKDD1A
1787:ZSCAN32
1773:C9orf64
1765:TMEM179
1633:Caudata
1020:Nuclear
244:) have
190:leucine
186:alanine
174:cytosol
60:daltons
50:Protein
3047:
3006:
2996:
2988:
2949:
2939:
2931:
2832:
2822:
2366:"ProP"
2169:"SAPS"
1952:ExPasy
1822:TMEM88
1810:SOWAHD
1794:SAMD10
1758:TMEM71
1751:STRING
1735:, and
1715:, nor
1659:, and
1620:, and
1596:, and
1478:0.960
1467:0.865
1456:0.850
1445:0.924
1434:0.942
1423:0.902
1412:0.935
1401:0.953
1379:0.989
1368:0.914
1357:0.803
1346:0.992
1335:0.836
1324:0.935
1310:0.906
1299:0.888
1288:0.859
823:Humans
240:, and
200:, and
194:lysine
2815:BLAST
1641:BLAST
1637:Apoda
1629:Anura
1228:KRAB/
1168:Golgi
272:Human
3045:ISSN
3004:PMID
2986:ISSN
2947:PMID
2929:ISSN
2830:OCLC
2820:ISBN
2674:2019
2649:2019
2619:2019
2594:2019
2564:2019
2539:2019
2509:2019
2479:2019
2449:2019
2068:2019
2039:2019
1934:2019
1897:2019
1681:rays
1604:and
1193:11.1
1156:11.1
1151:11.1
1119:11.1
1050:17.4
1035:52.2
1013:34.8
1003:22.2
988:11.1
954:11.1
932:11.1
927:17.4
922:30.4
917:22.2
900:66.7
895:55.6
885:39.1
880:55.6
810:for
424:1076
188:and
141:The
76:Exon
38:Gene
3035:doi
2994:PMC
2978:doi
2937:PMC
2921:doi
1685:not
1679:or
1673:not
1643:or
1472:20
1461:19
1450:18
1439:17
1428:16
1417:15
1406:14
1395:13
1384:12
1373:11
1362:10
1124:8.7
1109:4.3
1087:4.3
1072:8.7
1067:8.7
1030:8.7
998:8.7
976:4.3
964:4.3
942:8.7
890:4.3
572:102
557:129
498:N/A
493:N/A
488:N/A
483:N/A
419:538
414:574
409:999
404:765
399:743
3065::
3043:.
3029:.
3025:.
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2992:.
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1576:,
1390:1
1351:9
1340:8
1329:7
1315:6
1304:5
1293:4
1282:3
1277:1
1271:2
1266:1
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993:13
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567:54
562:70
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1161:0
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1136:0
1114:0
1104:0
1099:0
1082:0
1077:0
1062:0
1045:0
1040:0
1025:0
1008:0
971:0
959:0
937:0
757:3
752:3
747:3
742:3
737:3
732:3
720:1
715:0
710:1
705:1
700:2
695:2
683:0
678:1
673:1
668:0
663:1
658:1
646:0
641:0
636:0
631:0
626:1
621:1
609:3
604:3
599:3
594:3
589:3
584:3
535:4
530:8
525:0
520:2
515:3
510:3
478:3
473:3
461:4
456:0
451:0
446:1
441:1
436:1
387:3
382:3
377:3
372:3
367:3
362:3
350:2
345:2
340:1
335:0
330:2
325:2
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