1580:
1567:
1554:
881:
925:
934:
905:
893:
234:
211:
108:
133:
1184:
1536:
240:
139:
1579:
1566:
1553:
3308:
854:
880:
864:
Studies have found that after using single nucleotide polymorphism (SNP) genotyping array method the TMEM19 gene was identified to be associated with ammonia nitrogen tolerance. Using a genome-wide association study of individuals with non-syndromic cleft lip with palate (NSCLP) to identify loci that
1016:
Plays a role in regulating the plasma triglyceride levels, a major risk factor of CAD. Is a component of high-density lipoprotein, similar to a rat protein that is upregulated in response to liver injury. Mutations in the gene are associated with hypertriglyceridemia and hyperlipoproteinemia type 5.
873:
The mRNA transcript of TMEM19 is 5662 base pairs. The TMEM19 transcript was found to be expressed in most tissues but has increased expression in duodenum, kidney, skin, small intestine, and urinary bladder. in a non-alcoholic fatty liver disease (NAFLD) model in cells that were subjected to glucose
1540:
Sequence
Divergence of TMEM19. The sequence divergence of TMEM19 was compared alongside Cytochrome C and Fibrinogen alpha. Sequence identity of each protein was determined in order to find the sequence divergence. The sequence divergence was used to calculate the corrected divergence (M). A line of
920:
TMEM19 is a protein spanning 336 amino acids. It has 6 transmembrane regions. The protein is found at moderate levels in the body, with the highest expression found in superior cervical ganglia and cardiac myocytes. TMEM19 interacts with many proteins, most of these proteins are localized around
1546:
TMEM19 Orthologs were sorted by the median date of divergence. TMEM19 has a median date of divergence greater than 1598 MYA which is found in Thale cress. TMEM19 does not have any paralogs, this was determined after running TMEM19 through BLAST. The human TMEM19 protein is closely related to
928:
Data was obtained from a large-scale analysis of the human transcriptome on NCBI Geo. The data contains expression patterns of TMEM19 in different tissues in the body. The value in red shows the amount of expression and the blue dot signifies the rank of expression compared to other protein
996:
Also known as Seipin, a multi-pass transmembrane protein. Localized in the ER and is predicted to be associated with lipid droplet morphology. Mutations of this gene leads to
Berardinelli-Seip syndrome which results in absence of adipose tissue and severe insulin resistance. (NCBI)
904:
892:
1187:
Visual predicted representation of TMEM19 in the cell membrane. In image A the transmembrane regions were selected using NCBI and in image B the seventh predicted transmembrane region found from SOSUI analysis was added. Amino acids in red are sites of kinase
1585:
TMEM19 Strict
Orthologs (Vertebrates) Multiple Sequence Alignment. Sequences were aligned using ClustalO, transmembrane regions and exons were boxed. Consensus of amino acids are shown at 100% and 90%. Amino acids are colored based on their physicochemical
1572:
TMEM19 Strict
Orthologs (Vertebrates) Multiple Sequence Alignment. Sequences were aligned using ClustalO, transmembrane regions and exons were boxed. Consensus of amino acids are shown at 100% and 90%. Amino acids are colored based on their physicochemical
1559:
TMEM19 Strict
Orthologs (Vertebrates) Multiple Sequence Alignment. Sequences were aligned using ClustalO, transmembrane regions and exons were boxed. Consensus of amino acids are shown at 100% and 90%. Amino acids are colored based on their physicochemical
1168:
Normally found in the membrane of ER. Upon stress to ER the protein is cleaved and released into the cytoplasm where is translocated to the nucleus. It then activates the transcription of target genes by binding to box-B elements. (NCBI)
910:
A conceptual translation of the human TMEM19 was made using data from NCBI and translated using Six Frame
Translations. Transmembrane regions are highlighted in gray, and highly conserved regions are bolded.
898:
A conceptual translation of the human TMEM19 was made using data from NCBI and translated using Six Frame
Translations. Transmembrane regions are highlighted in gray, and highly conserved regions are bolded.
886:
A conceptual translation of the human TMEM19 was made using data from NCBI and translated using Six Frame
Translations. Transmembrane regions are highlighted in gray, and highly conserved regions are bolded.
1148:
Transcription factor that bind to cAMP-response element and regulates cell proliferation. Also plays a role in leukocyte migration, tumor suppression, and ER stress-associated protein degradation. (NCBI)
247:
146:
937:
TMEM19 expression in Mus musculus brain. A sagittal slice of a mouse midbrain shows expression of TMEM19 shown in purple. The image was collected by the Allen Brain Map.
1112:
G protein-coupled receptor from cannabinoid family. Related to CB1 which is responsible for the efficacy of THC. Mainly expressed in cells of the immune system. (NCBI)
977:
Membrane-bound receptor and member of the melanocortin receptor family. Protein interacts with adrenocorticotropic and MSH hormones. Mediated by G proteins. (NCBI)
874:
deficiency or oxidative stress. This results in cell death due to excessive disulfide formation in actin cytoskeleton and actin filament called disulfidptosis.
559:
540:
69:
865:
are at risk for the birth defect. From this they were able to identify the loci of TMEM19 as a risk for this birth defect, along with 25 other loci.
924:
3358:
2469:
2451:
1200:
available. Phosphorylation sites are in order of decreasing score. AGC represents protein kinase A, protein kinase G, and protein kinase C.
861:
The TMEM19 gene is located on chromosome 12(12q21.1) spanning 18,966 base pairs on the + strand. The gene has a total of 6 exon regions.
233:
790:
783:
210:
1395:
3363:
2438:
2417:
3329:
1074:
Component of the T-cell receptor-CD3 complex. Mutations with this protein are associated with T cell immunodeficieny. (NCBI)
132:
107:
2434:
933:
2413:
1836:
246:
145:
3318:
2601:"Identification and validation of disulfidptosis-associated molecular clusters in non-alcoholic fatty liver disease"
239:
138:
604:
57:
2544:"Genome-wide analyses of non-syndromic cleft lip with palate identify 14 novel loci and genetic heterogeneity"
1547:
vertebrates and moderately related to fungi/plants. TMEM19 evolves at a rate that is related to cytochrome c.
1391:
1193:
966:
585:
1976:
1801:
1101:
121:
2931:"CREB3L1 cAMP responsive element binding protein 3 like 1 [Homo sapiens (Human)] - Gene - NCBI"
2811:"BSCL2 BSCL2 lipid droplet biogenesis associated, seipin [Homo sapiens (Human)] - Gene - NCBI"
2726:
2555:
2359:
44:
1183:
2079:
766:
762:
758:
707:
703:
699:
1731:
81:
2861:"CD3G CD3 gamma subunit of T-cell receptor complex [Homo sapiens (Human)] - Gene - NCBI"
1535:
754:
733:
695:
674:
1196:
sites in the protein sequence. The program was run on a medium threshold and scanned for every
2917:"CREB3 cAMP responsive element binding protein 3 [Homo sapiens (Human)] - Gene - NCBI"
2754:
2632:
2581:
2524:
2489:"Genome-wide association study identified genes associated with ammonia nitrogen tolerance in
2324:
2157:
2046:
1906:
37:
3264:"Integral membrane protein DUF92-domain-containing protein [Mucor muced - Protein - NCBI"
2744:
2734:
2622:
2612:
2571:
2563:
2514:
2504:
326:
257:
201:
156:
77:
1055:
Predicted to be located in mitochondrion. Possible link to Crohn's and sarcoidosis. (NCBI)
2184:
1984:
1509:
1483:
1457:
1431:
1365:
1339:
1287:
301:
3292:"Integral membrane protein (Protein of unknown function DUF92, transmem - Protein - NCBI"
3082:"PREDICTED: Transmembrane protein 19, partial [Gekko japonicus] - Protein - NCBI"
2730:
2627:
2600:
2559:
3291:
3277:
3263:
3249:
3235:
3221:
3207:
3193:
3179:
3165:
3151:
3137:
3123:
3109:
3095:
3081:
3067:
3053:
3039:
3025:
3011:
2576:
2543:
2519:
2488:
2011:
1949:
1871:
1313:
1261:
1235:
2749:
2714:
2686:
3352:
3068:"Transmembrane protein 19 isoform X1 [Dermochelys coriacea] - Protein - NCBI"
2149:
3250:"Transmembrane protein 19 isoform X1 [Stegostoma tigrinum] - Protein - NCBI"
2997:
2713:
Su AI, Wiltshire T, Batalov S, Lapp H, Ching KA, Block D, et al. (April 2004).
61:
3236:"Transmembrane protein 19 isoform X1 [Petromyzon marinus] - Protein - NCBI"
3054:"PREDICTED: Transmembrane protein 19 [Lipotes vexillifer] - Protein - NCBI"
2902:
2262:
319:
98:
3096:"Transmembrane protein 19 isoform X1 [Python bivittatus] - Protein - NCBI"
2810:
3110:"Transmembrane protein 19 isoform X2 [Zootoca vivipara] - Protein - NCBI"
85:
2474:
National Center for
Biotechnology Information, U.S. National Library of Medicine
2456:
National Center for
Biotechnology Information, U.S. National Library of Medicine
2367:
2254:
2219:
2019:
1774:
1025:
2719:
Proceedings of the National Academy of Sciences of the United States of America
2617:
402:
3124:"Transmembrane protein 19 [Dromaius novaehollandiae] - Protein - NCBI"
2772:
2658:"TMEM19 transmembrane protein 19 [Homo sapiens (human)] - Gene - NCBI"
2509:
2332:
218:
115:
65:
3222:"Transmembrane protein 19 [Hippoglossus stenolepis] - Protein - NCBI"
3166:"Transmembrane protein 19 [Gymnogyps californianus] - Protein - NCBI"
3012:"Transmembrane protein 19 isoform 1 [Mus musculus] - Protein - NCBI"
2973:
2739:
2297:
2122:
2114:
1704:
504:
462:
340:
285:
272:
184:
171:
73:
3307:
3194:"Transmembrane protein 19 [Rhinatrema bivittatum] - Protein - NCBI"
2848:
2823:
2797:"MC4R melanocortin 4 receptor [Homo sapiens (Human)] - Gene - NCBI"
2758:
2636:
2585:
2528:
3208:"Transmembrane protein 19 [Scleropages formosus] - Protein - NCBI"
3040:"Transmembrane protein 19 [Artibeus jamaicensis] - Protein - NCBI"
2930:
2916:
2889:"CNR2 cannabinoid receptor 2 [Homo sapiens (Human)] - Gene - NCBI"
2657:
830:
825:
2888:
2796:
2192:
1914:
1879:
1844:
1044:
814:
649:
630:
3026:"Transmembrane protein 19 [Suricata suricatta] - Protein - NCBI"
2874:
2860:
2835:
2567:
853:
3152:"Transmembrane protein 19 [Coturnix japonica] - Protein - NCBI"
2227:
1696:
1634:
1157:
616:
571:
3278:"Transmembrane protein [Lachnellula hyalina] - Protein - NCBI"
3138:"Transmembrane protein 19 [Rissa tridactyla] - Protein - NCBI"
1036:
Functions as a water channel in cells. Specific to the kidney. (NCBI)
2715:"A gene atlas of the mouse and human protein-encoding transcriptomes"
1809:
1669:
1197:
798:
526:
3180:"Transmembrane protein 19 [Xenopus laevis] - Protein - NCBI"
2542:
Yu Y, Zuo X, He M, Gao J, Fu Y, Qin C, et al. (February 2017).
2875:"CD79A CD79a molecule [Homo sapiens (Human)] - Gene - NCBI"
2998:"Transmembrane protein 19 [Homo sapiens] - Protein - NCBI"
2289:
1766:
1661:
1626:
1534:
1400:
1182:
1137:
1082:
1005:
985:
932:
923:
852:
2903:"CPLX4 complexin 4 [Homo sapiens (Human)] - Gene - NCBI"
2599:
Yu X, Guo Z, Fang Z, Yang K, Liu C, Dong Z, Liu C (2023-09-08).
2087:
1404:
1063:
2836:"AQP6 aquaporin 6 [Homo sapiens (Human)] - Gene - NCBI"
3301:
2974:"Clustal Omega < Multiple Sequence Alignment < EMBL-EBI"
1941:
1739:
1093:
The Ig-alpha protein of the B-cell antigen component. (NCBI)
990:
Bernardinelli-Seip Congenital Lipodystrophy Type 2 Protein
845:
is a protein that in humans is encoded by the TMEM19 gene.
2944:
309:
3325:
1541:
best fit was included to show the projected divergence.
1129:
May be involved in synaptic vesicle exocytosis. (NCBI)
3332:
to it so that it can be listed with similar articles.
474:
2773:"Gene Detail :: Allen Brain Atlas: Mouse Brain"
747:
726:
688:
667:
2430:
2428:
2426:
2409:
2407:
2405:
1162:cAMP responsive element binding protein 3 like 1
256:
155:
2435:GRCm38: Ensembl release 89: ENSMUSG00000069520
1068:CD3 gamma subunit of T-cell receptor complex
8:
2414:GRCh38: Ensembl release 89: ENSG00000139291
1590:
1202:
1142:cAMP responsive element binding protein 3
500:
297:
196:
93:
2748:
2738:
2626:
2616:
2575:
2518:
2508:
1192:Using BioCuckoo, TMEM19 was analyzed for
2849:https://www.ncbi.nlm.nih.gov/gene/256815
2824:https://www.ncbi.nlm.nih.gov/gene/116519
945:
2401:
1549:
876:
18:
2968:
2966:
2964:
2708:
2706:
1621:Sequence Similarity to Humans %
363:cardiac muscle tissue of right atrium
261:
222:
217:
160:
119:
114:
7:
2681:
2679:
2677:
2652:
2650:
2648:
2646:
1049:Chromosome 10 open reading frame 67
1618:Sequence Identity to Humans %
3317:needs additional or more specific
744:
723:
685:
664:
640:
621:
595:
576:
550:
531:
479:
397:
335:
314:
16:Protein encoded by the TMEM19 gene
14:
3306:
1578:
1565:
1552:
1179:Post translational modifications
903:
891:
879:
857:TMEM19 location on chromosome 12
245:
238:
232:
209:
144:
137:
131:
106:
463:More reference expression data
1:
921:membranes found in the cell.
429:epithelium of small intestine
230:
129:
3359:Genes on human chromosome 12
359:myocardium of left ventricle
3380:
2618:10.3389/fgene.2023.1251999
2487:Fu S, Liu J (2022-08-22).
1609:Median Date of Divergence
1592:Orthologs of Human TMEM19
48:, transmembrane protein 19
2510:10.3389/fgene.2022.961009
2470:"Mouse PubMed Reference:"
2452:"Human PubMed Reference:"
1837:Schlegal's Japanese Gecko
974:Ubiquitin Reconstruction
829:
824:
820:
813:
797:
791:Chr 10: 115.18 – 115.2 Mb
778:
751:
730:
719:
692:
671:
660:
647:
643:
628:
624:
615:
602:
598:
583:
579:
570:
557:
553:
538:
534:
525:
510:
503:
499:
487:
482:
473:
460:
409:
400:
347:
338:
308:
300:
296:
279:
266:
229:
208:
199:
195:
178:
165:
128:
105:
96:
92:
55:
52:
42:
35:
30:
26:
21:
1955:Dromaius novaehollandiae
971:Melanocortin 4 Receptor
843:Transmembrane protein 19
784:Chr 12: 71.69 – 71.71 Mb
2740:10.1073/pnas.0400782101
2687:"Six-Frame Translation"
2198:Hippoglossus stenolepis
1106:Cannabinoid receptor 2
3364:Transmembrane proteins
2945:"The CUCKOO Workgroup"
1977:Black Legged Kittiwake
1543:
1218:Protein Sequence Pos.
1204:Phosphorylation Sites
1189:
938:
930:
929:expression in tissues.
858:
371:pancreatic ductal cell
2605:Frontiers in Genetics
2548:Nature Communications
2497:Frontiers in Genetics
2128:Rhinatrema bivittatum
1538:
1186:
936:
927:
856:
433:stroma of bone marrow
224:Chromosome 10 (mouse)
122:Chromosome 12 (human)
2662:www.ncbi.nlm.nih.gov
2491:Litopenaeus vannamei
2373:Arabidopsis thaliana
2163:Scleropages formosus
2115:Two-Lined Caecillian
1815:Dermochelys coriacea
1745:Artibeus jamaicensis
1531:Evolutionary history
942:Protein Interactions
2777:mouse.brain-map.org
2731:2004PNAS..101.6062S
2568:10.1038/ncomms14364
2560:2017NatCo...814364Y
2338:Lachnellula hyalina
2268:Stegostoma tigrinum
2080:African Clawed Frog
1593:
1205:
2233:Petromyzon marinus
2228:Petromyzontiformes
1802:Leatherback Turtle
1780:Lipotes vexillifer
1732:Jamaican Fruit Bat
1710:Suricata suricatta
1606:Genus and Species
1591:
1544:
1203:
1190:
1010:Apolipoprotein A5
939:
931:
859:
605:ENSMUSG00000069520
421:left lobe of liver
86:TMEM19 - orthologs
3347:
3346:
3330:adding categories
2725:(16): 6062–6067.
2393:
2392:
2193:Pleuronectiformes
2158:Osteoglossiformes
2047:California Condor
2025:Coturnix japonica
1907:Viviparous Lizard
1885:Python bivittatus
1612:Accession Number
1528:
1527:
1176:
1175:
955:Detection Method
840:
839:
836:
835:
809:
808:
774:
773:
741:
740:
715:
714:
682:
681:
656:
655:
637:
636:
611:
610:
592:
591:
566:
565:
547:
546:
495:
494:
491:
490:
469:
468:
456:
455:
445:intestinal villus
394:
393:
387:bone marrow cells
292:
291:
191:
190:
3371:
3342:
3339:
3333:
3310:
3302:
3296:
3295:
3288:
3282:
3281:
3274:
3268:
3267:
3260:
3254:
3253:
3246:
3240:
3239:
3232:
3226:
3225:
3218:
3212:
3211:
3204:
3198:
3197:
3190:
3184:
3183:
3176:
3170:
3169:
3162:
3156:
3155:
3148:
3142:
3141:
3134:
3128:
3127:
3120:
3114:
3113:
3106:
3100:
3099:
3092:
3086:
3085:
3078:
3072:
3071:
3064:
3058:
3057:
3050:
3044:
3043:
3036:
3030:
3029:
3022:
3016:
3015:
3008:
3002:
3001:
2994:
2988:
2987:
2985:
2984:
2970:
2959:
2958:
2956:
2955:
2941:
2935:
2934:
2927:
2921:
2920:
2913:
2907:
2906:
2899:
2893:
2892:
2885:
2879:
2878:
2871:
2865:
2864:
2857:
2851:
2846:
2840:
2839:
2832:
2826:
2821:
2815:
2814:
2807:
2801:
2800:
2793:
2787:
2786:
2784:
2783:
2769:
2763:
2762:
2752:
2742:
2710:
2701:
2700:
2698:
2697:
2683:
2672:
2671:
2669:
2668:
2654:
2641:
2640:
2630:
2620:
2596:
2590:
2589:
2579:
2539:
2533:
2532:
2522:
2512:
2484:
2478:
2477:
2466:
2460:
2459:
2448:
2442:
2432:
2421:
2411:
2325:Ascomycete Fungi
2263:Orectolobiformes
1990:Rissa tridactyla
1920:Zootoca vivipara
1615:Sequence Length
1594:
1582:
1569:
1556:
1206:
1188:phosphorylation.
946:
907:
895:
883:
822:
821:
793:
786:
769:
745:
736:
724:
720:RefSeq (protein)
710:
686:
677:
665:
641:
622:
596:
577:
551:
532:
501:
480:
465:
405:
403:Top expressed in
398:
343:
341:Top expressed in
336:
315:
298:
288:
275:
264:
249:
242:
236:
225:
213:
197:
187:
174:
163:
148:
141:
135:
124:
110:
94:
88:
47:
40:
19:
3379:
3378:
3374:
3373:
3372:
3370:
3369:
3368:
3349:
3348:
3343:
3337:
3334:
3323:
3311:
3300:
3299:
3290:
3289:
3285:
3276:
3275:
3271:
3262:
3261:
3257:
3248:
3247:
3243:
3234:
3233:
3229:
3220:
3219:
3215:
3206:
3205:
3201:
3192:
3191:
3187:
3178:
3177:
3173:
3164:
3163:
3159:
3150:
3149:
3145:
3136:
3135:
3131:
3122:
3121:
3117:
3108:
3107:
3103:
3094:
3093:
3089:
3080:
3079:
3075:
3066:
3065:
3061:
3052:
3051:
3047:
3038:
3037:
3033:
3024:
3023:
3019:
3010:
3009:
3005:
2996:
2995:
2991:
2982:
2980:
2972:
2971:
2962:
2953:
2951:
2943:
2942:
2938:
2929:
2928:
2924:
2915:
2914:
2910:
2901:
2900:
2896:
2887:
2886:
2882:
2873:
2872:
2868:
2859:
2858:
2854:
2847:
2843:
2834:
2833:
2829:
2822:
2818:
2809:
2808:
2804:
2795:
2794:
2790:
2781:
2779:
2771:
2770:
2766:
2712:
2711:
2704:
2695:
2693:
2691:www.bioline.com
2685:
2684:
2675:
2666:
2664:
2656:
2655:
2644:
2598:
2597:
2593:
2541:
2540:
2536:
2486:
2485:
2481:
2468:
2467:
2463:
2450:
2449:
2445:
2433:
2424:
2412:
2403:
2398:
2380:NP_001190343.1
2345:XP_031007997.1
2310:XP_051459555.1
2275:XP_048404699.1
2240:XP_032815808.1
2205:XP_035003305.1
2185:Pacific Halibut
2170:XP_018611167.1
2135:XP_029453037.1
2100:NP_001085034.1
2065:XP_050753817.1
2058:Accipitriformes
2032:XP_015711317.1
1997:XP_054044439.1
1985:Charadriiformes
1962:XP_025956153.1
1927:XP_034984278.1
1892:XP_007423004.1
1857:XP_015261175.1
1850:Gekko japonicus
1822:XP_038233118.1
1787:XP_007448836.1
1752:XP_037017069.2
1717:XP_029810978.1
1682:NP_001346399.1
1587:
1583:
1574:
1570:
1561:
1557:
1533:
1194:phosphorylation
1181:
1087:CD79a molecule
944:
918:
911:
908:
899:
896:
887:
884:
871:
851:
831:View/Edit Mouse
826:View/Edit Human
789:
782:
779:Location (UCSC)
765:
761:
757:
753:
732:
706:
702:
698:
694:
673:
586:ENSG00000139291
461:
452:
447:
443:
439:
435:
431:
427:
423:
419:
417:proximal tubule
415:
401:
390:
385:
381:
377:
373:
369:
365:
361:
357:
353:
351:mucosa of ileum
339:
283:
270:
262:
252:
251:
250:
243:
223:
200:Gene location (
182:
169:
161:
151:
150:
149:
142:
120:
97:Gene location (
56:
43:
36:
17:
12:
11:
5:
3377:
3375:
3367:
3366:
3361:
3351:
3350:
3345:
3344:
3314:
3312:
3305:
3298:
3297:
3283:
3269:
3255:
3241:
3227:
3213:
3199:
3185:
3171:
3157:
3143:
3129:
3115:
3101:
3087:
3073:
3059:
3045:
3031:
3017:
3003:
2989:
2960:
2936:
2922:
2908:
2894:
2880:
2866:
2852:
2841:
2827:
2816:
2802:
2788:
2764:
2702:
2673:
2642:
2591:
2534:
2479:
2461:
2443:
2422:
2400:
2399:
2397:
2394:
2391:
2390:
2387:
2384:
2381:
2378:
2375:
2370:
2365:
2362:
2356:
2355:
2352:
2349:
2346:
2343:
2340:
2335:
2330:
2327:
2321:
2320:
2317:
2314:
2311:
2308:
2305:
2300:
2295:
2292:
2286:
2285:
2282:
2279:
2276:
2273:
2270:
2265:
2260:
2257:
2251:
2250:
2247:
2244:
2241:
2238:
2235:
2230:
2225:
2222:
2216:
2215:
2212:
2209:
2206:
2203:
2200:
2195:
2190:
2187:
2181:
2180:
2177:
2174:
2171:
2168:
2165:
2160:
2155:
2152:
2146:
2145:
2142:
2139:
2136:
2133:
2130:
2125:
2120:
2117:
2111:
2110:
2107:
2104:
2101:
2098:
2095:
2093:Xenopus laevis
2090:
2085:
2082:
2076:
2075:
2072:
2069:
2066:
2063:
2060:
2055:
2052:
2049:
2043:
2042:
2039:
2036:
2033:
2030:
2027:
2022:
2017:
2014:
2012:Japanese Quail
2008:
2007:
2004:
2001:
1998:
1995:
1992:
1987:
1982:
1979:
1973:
1972:
1969:
1966:
1963:
1960:
1957:
1952:
1950:Casuariiformes
1947:
1944:
1938:
1937:
1934:
1931:
1928:
1925:
1922:
1917:
1912:
1909:
1903:
1902:
1899:
1896:
1893:
1890:
1887:
1882:
1877:
1874:
1872:Burmese Python
1868:
1867:
1864:
1861:
1858:
1855:
1852:
1847:
1842:
1839:
1833:
1832:
1829:
1826:
1823:
1820:
1817:
1812:
1807:
1804:
1798:
1797:
1794:
1791:
1788:
1785:
1782:
1777:
1772:
1769:
1763:
1762:
1759:
1756:
1753:
1750:
1747:
1742:
1737:
1734:
1728:
1727:
1724:
1721:
1718:
1715:
1712:
1707:
1702:
1699:
1693:
1692:
1689:
1686:
1683:
1680:
1677:
1672:
1667:
1664:
1658:
1657:
1654:
1651:
1648:
1645:
1642:
1637:
1632:
1629:
1623:
1622:
1619:
1616:
1613:
1610:
1607:
1604:
1601:
1598:
1589:
1588:
1584:
1577:
1575:
1571:
1564:
1562:
1558:
1551:
1532:
1529:
1526:
1525:
1522:
1519:
1512:
1507:
1504:
1500:
1499:
1496:
1493:
1486:
1481:
1478:
1474:
1473:
1470:
1467:
1460:
1455:
1452:
1448:
1447:
1444:
1441:
1434:
1429:
1426:
1422:
1421:
1418:
1415:
1408:
1389:
1386:
1382:
1381:
1378:
1375:
1368:
1363:
1360:
1356:
1355:
1352:
1349:
1342:
1337:
1334:
1330:
1329:
1326:
1323:
1316:
1311:
1308:
1304:
1303:
1300:
1297:
1290:
1285:
1282:
1278:
1277:
1274:
1271:
1264:
1259:
1256:
1252:
1251:
1248:
1245:
1238:
1233:
1230:
1226:
1225:
1222:
1219:
1216:
1213:
1210:
1180:
1177:
1174:
1173:
1170:
1166:
1163:
1160:
1154:
1153:
1150:
1146:
1143:
1140:
1134:
1133:
1130:
1127:
1124:
1121:
1117:
1116:
1113:
1110:
1107:
1104:
1098:
1097:
1094:
1091:
1088:
1085:
1079:
1078:
1075:
1072:
1069:
1066:
1060:
1059:
1056:
1053:
1050:
1047:
1041:
1040:
1037:
1034:
1031:
1028:
1022:
1021:
1018:
1014:
1011:
1008:
1002:
1001:
998:
994:
991:
988:
982:
981:
978:
975:
972:
969:
963:
962:
959:
956:
953:
950:
943:
940:
917:
914:
913:
912:
909:
902:
900:
897:
890:
888:
885:
878:
870:
867:
850:
847:
838:
837:
834:
833:
828:
818:
817:
811:
810:
807:
806:
804:
802:
795:
794:
787:
780:
776:
775:
772:
771:
749:
748:
742:
739:
738:
728:
727:
721:
717:
716:
713:
712:
690:
689:
683:
680:
679:
669:
668:
662:
658:
657:
654:
653:
645:
644:
638:
635:
634:
626:
625:
619:
613:
612:
609:
608:
600:
599:
593:
590:
589:
581:
580:
574:
568:
567:
564:
563:
555:
554:
548:
545:
544:
536:
535:
529:
523:
522:
517:
512:
508:
507:
497:
496:
493:
492:
489:
488:
485:
484:
477:
471:
470:
467:
466:
458:
457:
454:
453:
451:
450:
446:
442:
438:
434:
430:
426:
422:
418:
414:
410:
407:
406:
395:
392:
391:
389:
388:
384:
380:
376:
372:
368:
367:jejunal mucosa
364:
360:
356:
352:
348:
345:
344:
332:
331:
323:
312:
306:
305:
302:RNA expression
294:
293:
290:
289:
281:
277:
276:
268:
265:
260:
254:
253:
244:
237:
231:
227:
226:
221:
215:
214:
206:
205:
193:
192:
189:
188:
180:
176:
175:
167:
164:
159:
153:
152:
143:
136:
130:
126:
125:
118:
112:
111:
103:
102:
90:
89:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
3376:
3365:
3362:
3360:
3357:
3356:
3354:
3341:
3338:December 2023
3331:
3327:
3321:
3320:
3315:This article
3313:
3309:
3304:
3303:
3293:
3287:
3284:
3279:
3273:
3270:
3265:
3259:
3256:
3251:
3245:
3242:
3237:
3231:
3228:
3223:
3217:
3214:
3209:
3203:
3200:
3195:
3189:
3186:
3181:
3175:
3172:
3167:
3161:
3158:
3153:
3147:
3144:
3139:
3133:
3130:
3125:
3119:
3116:
3111:
3105:
3102:
3097:
3091:
3088:
3083:
3077:
3074:
3069:
3063:
3060:
3055:
3049:
3046:
3041:
3035:
3032:
3027:
3021:
3018:
3013:
3007:
3004:
2999:
2993:
2990:
2979:
2978:www.ebi.ac.uk
2975:
2969:
2967:
2965:
2961:
2950:
2949:biocuckoo.org
2946:
2940:
2937:
2932:
2926:
2923:
2918:
2912:
2909:
2904:
2898:
2895:
2890:
2884:
2881:
2876:
2870:
2867:
2862:
2856:
2853:
2850:
2845:
2842:
2837:
2831:
2828:
2825:
2820:
2817:
2812:
2806:
2803:
2798:
2792:
2789:
2778:
2774:
2768:
2765:
2760:
2756:
2751:
2746:
2741:
2736:
2732:
2728:
2724:
2720:
2716:
2709:
2707:
2703:
2692:
2688:
2682:
2680:
2678:
2674:
2663:
2659:
2653:
2651:
2649:
2647:
2643:
2638:
2634:
2629:
2624:
2619:
2614:
2610:
2606:
2602:
2595:
2592:
2587:
2583:
2578:
2573:
2569:
2565:
2561:
2557:
2553:
2549:
2545:
2538:
2535:
2530:
2526:
2521:
2516:
2511:
2506:
2502:
2498:
2494:
2492:
2483:
2480:
2475:
2471:
2465:
2462:
2457:
2453:
2447:
2444:
2440:
2436:
2431:
2429:
2427:
2423:
2419:
2415:
2410:
2408:
2406:
2402:
2395:
2388:
2385:
2382:
2379:
2376:
2374:
2371:
2369:
2366:
2363:
2361:
2358:
2357:
2353:
2350:
2347:
2344:
2341:
2339:
2336:
2334:
2331:
2328:
2326:
2323:
2322:
2318:
2315:
2312:
2309:
2306:
2304:
2301:
2299:
2296:
2293:
2291:
2288:
2287:
2283:
2280:
2277:
2274:
2271:
2269:
2266:
2264:
2261:
2258:
2256:
2253:
2252:
2248:
2245:
2242:
2239:
2236:
2234:
2231:
2229:
2226:
2223:
2221:
2218:
2217:
2213:
2210:
2207:
2204:
2201:
2199:
2196:
2194:
2191:
2188:
2186:
2183:
2182:
2178:
2175:
2172:
2169:
2166:
2164:
2161:
2159:
2156:
2153:
2151:
2150:Asian Arowana
2148:
2147:
2143:
2140:
2137:
2134:
2131:
2129:
2126:
2124:
2121:
2118:
2116:
2113:
2112:
2108:
2105:
2102:
2099:
2096:
2094:
2091:
2089:
2086:
2083:
2081:
2078:
2077:
2073:
2070:
2067:
2064:
2061:
2059:
2056:
2053:
2050:
2048:
2045:
2044:
2040:
2037:
2034:
2031:
2028:
2026:
2023:
2021:
2018:
2015:
2013:
2010:
2009:
2005:
2002:
1999:
1996:
1993:
1991:
1988:
1986:
1983:
1980:
1978:
1975:
1974:
1970:
1967:
1964:
1961:
1958:
1956:
1953:
1951:
1948:
1945:
1943:
1940:
1939:
1935:
1932:
1929:
1926:
1923:
1921:
1918:
1916:
1913:
1910:
1908:
1905:
1904:
1900:
1897:
1894:
1891:
1888:
1886:
1883:
1881:
1878:
1875:
1873:
1870:
1869:
1865:
1862:
1859:
1856:
1853:
1851:
1848:
1846:
1843:
1840:
1838:
1835:
1834:
1830:
1827:
1824:
1821:
1818:
1816:
1813:
1811:
1808:
1805:
1803:
1800:
1799:
1795:
1792:
1789:
1786:
1783:
1781:
1778:
1776:
1773:
1770:
1768:
1767:Baiji Dolphin
1765:
1764:
1760:
1757:
1754:
1751:
1748:
1746:
1743:
1741:
1738:
1735:
1733:
1730:
1729:
1725:
1722:
1719:
1716:
1713:
1711:
1708:
1706:
1703:
1700:
1698:
1695:
1694:
1690:
1687:
1684:
1681:
1678:
1676:
1673:
1671:
1668:
1665:
1663:
1660:
1659:
1655:
1652:
1649:
1646:
1643:
1641:
1638:
1636:
1633:
1630:
1628:
1625:
1624:
1620:
1617:
1614:
1611:
1608:
1605:
1602:
1599:
1596:
1595:
1581:
1576:
1568:
1563:
1555:
1550:
1548:
1542:
1537:
1530:
1523:
1520:
1517:
1513:
1511:
1508:
1505:
1502:
1501:
1497:
1494:
1491:
1487:
1485:
1482:
1479:
1476:
1475:
1471:
1468:
1465:
1461:
1459:
1456:
1453:
1450:
1449:
1445:
1442:
1439:
1435:
1433:
1430:
1427:
1424:
1423:
1419:
1416:
1413:
1409:
1407:
1406:
1402:
1397:
1393:
1390:
1387:
1384:
1383:
1379:
1376:
1373:
1369:
1367:
1364:
1361:
1358:
1357:
1353:
1350:
1347:
1343:
1341:
1338:
1335:
1332:
1331:
1327:
1324:
1321:
1317:
1315:
1312:
1309:
1306:
1305:
1301:
1298:
1295:
1291:
1289:
1286:
1283:
1280:
1279:
1275:
1272:
1269:
1265:
1263:
1260:
1257:
1254:
1253:
1249:
1246:
1243:
1239:
1237:
1234:
1231:
1228:
1227:
1223:
1220:
1217:
1214:
1211:
1208:
1207:
1201:
1199:
1195:
1185:
1178:
1171:
1167:
1164:
1161:
1159:
1156:
1155:
1151:
1147:
1144:
1141:
1139:
1136:
1135:
1131:
1128:
1125:
1122:
1119:
1118:
1114:
1111:
1108:
1105:
1103:
1100:
1099:
1095:
1092:
1089:
1086:
1084:
1081:
1080:
1076:
1073:
1070:
1067:
1065:
1062:
1061:
1057:
1054:
1051:
1048:
1046:
1043:
1042:
1038:
1035:
1032:
1029:
1027:
1024:
1023:
1019:
1015:
1012:
1009:
1007:
1004:
1003:
999:
995:
992:
989:
987:
984:
983:
979:
976:
973:
970:
968:
965:
964:
960:
957:
954:
951:
948:
947:
941:
935:
926:
922:
915:
906:
901:
894:
889:
882:
877:
875:
868:
866:
862:
855:
848:
846:
844:
832:
827:
823:
819:
816:
812:
805:
803:
800:
796:
792:
788:
785:
781:
777:
770:
768:
764:
760:
756:
750:
746:
743:
737:
735:
729:
725:
722:
718:
711:
709:
705:
701:
697:
691:
687:
684:
678:
676:
670:
666:
663:
661:RefSeq (mRNA)
659:
652:
651:
646:
642:
639:
633:
632:
627:
623:
620:
618:
614:
607:
606:
601:
597:
594:
588:
587:
582:
578:
575:
573:
569:
562:
561:
556:
552:
549:
543:
542:
537:
533:
530:
528:
524:
521:
518:
516:
513:
509:
506:
502:
498:
486:
481:
478:
476:
472:
464:
459:
448:
444:
440:
436:
432:
428:
424:
420:
416:
412:
411:
408:
404:
399:
396:
386:
382:
379:skin of thigh
378:
374:
370:
366:
362:
358:
354:
350:
349:
346:
342:
337:
334:
333:
330:
328:
324:
322:
321:
317:
316:
313:
311:
307:
303:
299:
295:
287:
282:
278:
274:
269:
263:10|10 D2
259:
255:
248:
241:
235:
228:
220:
216:
212:
207:
203:
198:
194:
186:
181:
177:
173:
168:
158:
154:
147:
140:
134:
127:
123:
117:
113:
109:
104:
100:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
3335:
3316:
3286:
3272:
3258:
3244:
3230:
3216:
3202:
3188:
3174:
3160:
3146:
3132:
3118:
3104:
3090:
3076:
3062:
3048:
3034:
3020:
3006:
2992:
2981:. Retrieved
2977:
2952:. Retrieved
2948:
2939:
2925:
2911:
2897:
2883:
2869:
2855:
2844:
2830:
2819:
2805:
2791:
2780:. Retrieved
2776:
2767:
2722:
2718:
2694:. Retrieved
2690:
2665:. Retrieved
2661:
2608:
2604:
2594:
2551:
2547:
2537:
2500:
2496:
2490:
2482:
2473:
2464:
2455:
2446:
2372:
2337:
2303:Mucor mucedo
2302:
2267:
2232:
2197:
2162:
2127:
2092:
2057:
2024:
1989:
1954:
1919:
1884:
1849:
1814:
1779:
1775:Artiodactyla
1744:
1709:
1675:Mus musculus
1674:
1647:NP_060749.2
1640:Homo sapiens
1639:
1597:Common Name
1545:
1539:
1515:
1489:
1463:
1437:
1411:
1399:
1371:
1345:
1319:
1293:
1267:
1241:
1191:
1123:Complexin 4
1030:Aquaporin 6
958:Description
919:
872:
863:
860:
842:
841:
767:NP_001346401
763:NP_001346400
759:NP_001346399
752:
731:
708:NM_001359472
704:NM_001359471
700:NM_001359470
693:
672:
648:
629:
603:
584:
558:
539:
519:
514:
425:human kidney
413:right kidney
325:
318:
284:115,198,406
271:115,175,579
53:External IDs
2611:: 1251999.
2368:Brassicales
2360:Thale Cress
2255:Zebra Shark
2220:Sea Lamprey
2123:Gymnophiona
2020:Galliformes
1586:properties.
1573:properties.
1560:properties.
1165:Two Hybrid
1145:Two Hybrid
1126:Two Hybrid
1109:Two Hybrid
1090:Two Hybrid
1071:Two Hybrid
1052:Two Hybrid
1033:Two Hybrid
1013:Two Hybrid
993:Two Hybrid
383:skin of hip
355:skin of arm
183:71,705,047
170:71,686,082
31:Identifiers
3353:Categories
3319:categories
2983:2023-12-16
2954:2023-12-07
2782:2023-12-16
2696:2023-12-16
2667:2023-12-16
2503:: 961009.
2441:, May 2017
2420:, May 2017
2396:References
2333:Helotiales
2119:Amphibian
2084:Amphibian
2054:Gymnogyps
1810:Testudines
952:Full Name
869:Transcript
329:(ortholog)
66:HomoloGene
2554:: 14364.
2298:Mucorales
2290:Pin Mould
1705:Carnivora
1209:Position
755:NP_598444
734:NP_060749
696:NM_133683
675:NM_018279
505:Orthologs
74:GeneCards
3326:help out
2759:15075390
2637:37745847
2628:10514914
2586:28232668
2529:36072655
2437:–
2416:–
1915:Squamata
1911:Reptile
1880:Squamata
1876:Reptile
1845:Squamata
1841:Reptile
1806:Reptile
1670:Rodentia
1635:Primates
1518:TGLDEST
1492:SASWMCL
1466:KEGGQRN
1440:NKARHIA
1414:PRLITTW
1374:TGMVVNS
1348:GMVVNSP
1322:KLTKWKG
1296:WASEVGP
1270:NGGVTVV
1244:KSSPRLI
1045:C10orf67
949:Protein
815:Wikidata
449:yolk sac
437:duodenum
375:duodenum
3324:Please
2727:Bibcode
2577:5333091
2556:Bibcode
2520:9441690
2439:Ensembl
2418:Ensembl
1771:Mammal
1736:Mammal
1701:Mammal
1697:Meerkat
1666:Mammal
1631:Mammal
1524:0.7641
1521:0.9762
1514:YLGATMQ
1498:0.7641
1495:0.8679
1488:PVDFSKQ
1472:0.7641
1469:0.7851
1462:KKRLDSE
1446:0.0532
1443:0.2926
1436:GMVVNSP
1420:0.0403
1417:0.1546
1410:GPVLSKS
1380:0.0532
1377:0.1517
1370:QYTGLDE
1354:0.0532
1351:0.1427
1344:YTGLDES
1328:0.0197
1325:0.1333
1318:LMFFLSS
1302:0.0532
1299:0.0666
1292:LACSAGD
1276:0.0197
1273:0.0568
1266:WEKVPVG
1250:0.0197
1247:0.0559
1240:SEVGPVL
1224:Cutoff
1215:Kinase
1158:CREB3L1
1017:(NCBI)
916:Protein
617:UniProt
572:Ensembl
511:Species
304:pattern
162:12q21.1
62:1914476
38:Aliases
2757:
2750:395923
2747:
2635:
2625:
2584:
2574:
2527:
2517:
2364:Plant
2329:Fungi
2294:Fungi
2281:73.59
2246:63.35
2211:67.87
2176:69.33
2141:76.12
2106:76.12
2038:76.13
2003:77.31
1968:77.38
1933:79.85
1898:80.06
1863:81.23
1828:82.26
1793:89.58
1758:90.45
1723:91.92
1688:87.46
1627:Humans
1603:Order
1600:Class
1221:Score
1198:kinase
1120:CPLX4
801:search
799:PubMed
650:Q91W52
631:Q96HH6
527:Entrez
475:BioGPS
78:TMEM19
45:TMEM19
22:TMEM19
2386:34.6
2377:1598
2354:35.9
2351:23.3
2342:1275
2319:47.7
2316:32.8
2307:1275
2284:80.5
2259:Fish
2224:Fish
2189:Fish
2179:84.5
2154:Fish
2144:89.3
2109:89.3
2088:Anura
2074:89.6
2071:77.4
2051:Bird
2041:86.4
2016:Bird
2006:82.3
1981:Bird
1971:89.3
1946:Bird
1936:88.3
1901:80.1
1866:77.4
1831:89.9
1796:90.8
1761:95.5
1726:96.4
1691:90.3
1662:Mouse
1212:Code
1172:0.56
1152:0.56
1138:CREB3
1132:0.56
1115:0.56
1096:0.56
1083:CD79A
1077:0.56
1058:0.56
1039:0.56
1020:0.56
1006:APOA5
1000:0.67
986:BSCL2
980:0.37
560:67226
541:55266
520:Mouse
515:Human
327:Mouse
320:Human
267:Start
202:Mouse
166:Start
99:Human
70:10107
2755:PMID
2633:PMID
2582:PMID
2525:PMID
2383:288
2348:383
2313:284
2278:354
2272:462
2243:362
2237:563
2208:335
2202:429
2173:336
2167:429
2138:336
2132:352
2103:336
2097:352
2068:336
2062:319
2035:344
2029:319
2000:367
1994:319
1965:336
1959:319
1930:336
1924:319
1895:371
1889:319
1860:282
1854:319
1825:335
1819:319
1790:358
1755:336
1740:Bats
1720:336
1685:351
1656:100
1653:100
1650:336
1503:281
1477:167
1451:125
1425:296
1396:MAPK
1385:200
1359:287
1333:288
1307:108
1281:187
1255:214
1229:197
1102:CNR2
1064:CD3G
1026:AQP6
967:MC4R
849:Gene
310:Bgee
258:Band
219:Chr.
157:Band
116:Chr.
3328:by
2745:PMC
2735:doi
2723:101
2623:PMC
2613:doi
2572:PMC
2564:doi
2515:PMC
2505:doi
2389:50
2249:73
2214:83
1942:Emu
1784:94
1749:94
1714:94
1679:87
1432:CK1
1405:CLK
1401:GSK
1392:CDK
1366:CK1
1340:CK1
1314:AGC
1288:CK1
1262:AGC
1236:AGC
961:CV
483:n/a
441:lip
280:End
179:End
82:OMA
58:MGI
3355::
2976:.
2963:^
2947:.
2775:.
2753:.
2743:.
2733:.
2721:.
2717:.
2705:^
2689:.
2676:^
2660:.
2645:^
2631:.
2621:.
2609:14
2607:.
2603:.
2580:.
2570:.
2562:.
2550:.
2546:.
2523:.
2513:.
2501:13
2499:.
2495:.
2472:.
2454:.
2425:^
2404:^
1644:0
1510:TK
1506:Y
1484:TK
1480:Y
1458:TK
1454:Y
1428:T
1403:,
1398:,
1394:,
1388:S
1362:S
1336:T
1310:S
1284:T
1258:T
1232:S
286:bp
273:bp
185:bp
172:bp
80:;
76::
72:;
68::
64:;
60::
3340:)
3336:(
3322:.
3294:.
3280:.
3266:.
3252:.
3238:.
3224:.
3210:.
3196:.
3182:.
3168:.
3154:.
3140:.
3126:.
3112:.
3098:.
3084:.
3070:.
3056:.
3042:.
3028:.
3014:.
3000:.
2986:.
2957:.
2933:.
2919:.
2905:.
2891:.
2877:.
2863:.
2838:.
2813:.
2799:.
2785:.
2761:.
2737::
2729::
2699:.
2670:.
2639:.
2615::
2588:.
2566::
2558::
2552:8
2531:.
2507::
2493:"
2476:.
2458:.
1516:Y
1490:Y
1464:Y
1438:T
1412:S
1372:S
1346:T
1320:S
1294:T
1268:T
1242:S
204:)
101:)
84::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
