244:
221:
118:
143:
509:
502:
495:
250:
149:
1867:
1752:
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P,
1634:
Tiacci E, Orvietani PL, Bigerna B, Pucciarini A, Corthals GL, Pettirossi V, Martelli MP, Liso A, Benedetti R, Pacini R, Bolli N, Pileri S, Pulford K, Gambacorta M, Carbone A, Pasquarello C, Scherl A, Robertson H, Sciurpi MT, Alunni-Bistocchi G, Binaglia L, Byrne JA, Falini B (2005).
1206:
Byrne JA, Tomasetto C, Garnier JM, Rouyer N, Mattei MG, Bellocq JP, Rio MC, Basset P (August 1995). "A screening method to identify genes commonly overexpressed in carcinomas and the identification of a novel complementary DNA sequence".
1251:
Byrne JA, Nourse CR, Basset P, Gunning P (February 1998). "Identification of homo- and heteromeric interactions between members of the breast carcinoma-associated D52 protein family using the yeast two-hybrid system".
1295:
Wilson SH, Bailey AM, Nourse CR, Mattei MG, Byrne JA (August 2001). "Identification of MAL2, a novel member of the mal proteolipid family, though interactions with TPD52-like proteins in the yeast two-hybrid system".
1753:
Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network".
1827:
Cao Q, Chen J, Zhu L, Liu Y, Zhou Z, Sha J, Wang S, Li J (2006). "A testis-specific and testis developmentally regulated tumor protein D52 (TPD52)-like protein TPD52L3/hD55 interacts with TPD52 family proteins".
1511:
Wilson SH, Bailey AM, Nourse CR, Mattei MG, Byrne JA (2001). "Identification of MAL2, a novel member of the mal proteolipid family, though interactions with TPD52-like proteins in the yeast two-hybrid system".
1444:
Byrne JA, Nourse CR, Basset P, Gunning P (1998). "Identification of homo- and heteromeric interactions between members of the breast carcinoma-associated D52 protein family using the yeast two-hybrid system".
1570:
Boutros R, Bailey AM, Wilson SH, Byrne JA (2003). "Alternative splicing as a mechanism for regulating 14-3-3 binding: interactions between hD53 (TPD52L1) and 14-3-3 proteins".
1365:
Chen SL, Maroulakou IG, Green JE, Romano-Spica V, Modi W, Lautenberger J, Bhat NK (1996). "Isolation and characterization of a novel gene expressed in multiple cancers".
1798:
Barbaric D, Byth K, Dalla-Pozza L, Byrne JA (2007). "Expression of tumor protein D52-like genes in childhood leukemia at diagnosis: clinical and sample considerations".
1415:
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library".
257:
156:
1599:
Wang R, Xu J, SaramΓ€ki O, Visakorpi T, Sutherland WM, Zhou J, Sen B, Lim SD, Mabjeesh N, Amin M, Dong JT, Petros JA, Nelson PS, Marshall FF, Zhau HE, Chung LW (2004).
1386:
Byrne JA, Mattei MG, Basset P (1996). "Definition of the tumor protein D52 (TPD52) gene family through cloning of D52 homologues in human (hD53) and mouse (mD52)".
1680:
Byrne JA, Balleine RL, Schoenberg Fejzo M, Mercieca J, Chiew YE, Livnat Y, St Heaps L, Peters GB, Byth K, Karlan BY, Slamon DJ, Harnett P, Defazio A (2005).
1601:"PrLZ, a novel prostate-specific and androgen-responsive gene of the TPD52 family, amplified in chromosome 8q21.1 and overexpressed in human prostate cancer"
702:
79:
683:
1723:
Boutros R, Byrne JA (2005). "D53 (TPD52L1) is a cell cycle-regulated protein maximally expressed at the G2-M transition in breast cancer cells".
1637:"Tumor protein D52 (TPD52): a novel B-cell/plasma-cell molecule with unique expression pattern and Ca(2+)-dependent association with annexin VI"
1936:
1912:
1188:
1170:
1931:
1336:
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides".
243:
1014:
220:
1021:
1234:
1157:
1136:
1541:
Sathasivam P, Bailey AM, Crossley M, Byrne JA (2001). "The role of the coiled-coil motif in interactions mediated by TPD52".
1153:
1482:
Hoja MR, Wahlestedt C, HΓΆΓΆg C (2000). "A visual intracellular classification strategy for uncharacterized human proteins".
142:
117:
1132:
59:
1096:
256:
155:
249:
148:
1905:
747:
67:
728:
1898:
1762:
131:
46:
997:
993:
989:
975:
971:
967:
963:
944:
934:
930:
926:
922:
918:
898:
894:
890:
876:
872:
868:
864:
849:
845:
837:
827:
823:
819:
815:
811:
1786:
1711:
1470:
1277:
91:
979:
948:
880:
841:
1845:
1815:
1778:
1740:
1703:
1682:"Tumor protein D52 (TPD52) is overexpressed and a gene amplification target in ovarian cancer"
1668:
1622:
1587:
1558:
1529:
1499:
1462:
1432:
1403:
1374:
1353:
1313:
1269:
1216:
508:
501:
494:
39:
1882:
1837:
1807:
1770:
1732:
1693:
1658:
1648:
1612:
1579:
1550:
1521:
1491:
1454:
1424:
1395:
1345:
1305:
1261:
336:
267:
211:
166:
87:
311:
1766:
1583:
1428:
617:
612:
607:
591:
586:
581:
565:
560:
555:
550:
1925:
1349:
537:
1715:
1878:
1790:
1474:
1281:
329:
108:
71:
1811:
1617:
1600:
95:
1736:
1193:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1175:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1108:
1841:
1653:
1636:
412:
228:
125:
75:
647:
472:
350:
295:
282:
194:
181:
83:
1849:
1819:
1782:
1744:
1707:
1672:
1626:
1591:
1562:
1554:
1533:
1525:
1503:
1495:
1458:
1399:
1317:
1309:
1265:
1466:
1436:
1407:
1378:
1357:
1273:
1220:
1061:
1056:
1045:
792:
773:
1774:
1663:
1104:
1100:
1077:
759:
714:
1698:
1681:
1029:
669:
1866:
632:
628:
1874:
1084:
63:
517:
319:
1886:
484:
962:
917:
863:
810:
1149:
1147:
1145:
1128:
1126:
1124:
266:
165:
50:, D52, N8L, PC-1, PrLZ, hD52, tumor protein D52
18:Protein-coding gene in the species Homo sapiens
1154:GRCm38: Ensembl release 89: ENSMUSG00000027506
1906:
1246:
1244:
8:
1133:GRCh38: Ensembl release 89: ENSG00000076554
1913:
1899:
959:
914:
860:
807:
643:
533:
307:
206:
103:
1697:
1662:
1652:
1616:
1120:
1235:"Entrez Gene: TPD52 tumor protein D52"
423:crypt of lieberkuhn of small intestine
20:
271:
232:
227:
170:
129:
124:
7:
1863:
1861:
566:protein heterodimerization activity
1885:. You can help Knowledge (XXG) by
783:
764:
738:
719:
693:
674:
613:anatomical structure morphogenesis
489:
407:
345:
324:
14:
1080:that in humans is encoded by the
561:protein homodimerization activity
365:lateral nuclear group of thalamus
1865:
507:
500:
493:
255:
248:
242:
219:
154:
147:
141:
116:
587:perinuclear region of cytoplasm
518:More reference expression data
473:More reference expression data
1:
1937:Human chromosome 8 gene stubs
1830:Biochem. Biophys. Res. Commun
1812:10.1016/j.leukres.2006.03.009
1618:10.1158/0008-5472.CAN-03-3331
1584:10.1016/S0022-2836(03)00944-6
1543:Biochem. Biophys. Res. Commun
1429:10.1016/S0378-1119(97)00411-3
240:
139:
1350:10.1016/0378-1119(94)90802-8
1932:Genes on human chromosome 8
1737:10.1016/j.yexcr.2005.07.009
1953:
1860:
1842:10.1016/j.bbrc.2006.03.208
1654:10.1182/blood-2004-07-2630
1189:"Mouse PubMed Reference:"
1171:"Human PubMed Reference:"
1060:
1055:
1051:
1044:
1028:
1009:
986:
941:
910:
887:
834:
803:
790:
786:
771:
767:
758:
745:
741:
726:
722:
713:
700:
696:
681:
677:
668:
653:
646:
642:
626:
536:
532:
515:
492:
483:
470:
419:
410:
393:epithelium of nasopharynx
357:
348:
318:
310:
306:
289:
276:
239:
218:
209:
205:
188:
175:
138:
115:
106:
102:
57:
54:
44:
37:
32:
28:
23:
1095:TPD52 has been shown to
1015:Chr 8: 80.03 β 80.23 Mb
373:mucosa of sigmoid colon
1555:10.1006/bbrc.2001.5721
1526:10.1006/geno.2001.6610
1496:10.1006/excr.2000.4948
1459:10.1038/sj.onc.1201604
1400:10.1006/geno.1996.0393
1310:10.1006/geno.2001.6610
1266:10.1038/sj.onc.1201604
608:B cell differentiation
455:neural layer of retina
1022:Chr 3: 8.99 β 9.07 Mb
592:endoplasmic reticulum
447:epithelium of stomach
234:Chromosome 3 (mouse)
132:Chromosome 8 (human)
1775:10.1038/nature04209
1767:2005Natur.437.1173R
551:calcium ion binding
443:submandibular gland
381:islet of Langerhans
1873:This article on a
748:ENSMUSG00000027506
601:Biological process
575:Cellular component
544:Molecular function
1894:
1893:
1699:10.1002/ijc.21250
1074:Tumor protein D52
1071:
1070:
1067:
1066:
1040:
1039:
1005:
1004:
956:
955:
906:
905:
857:
856:
799:
798:
780:
779:
754:
753:
735:
734:
709:
708:
690:
689:
638:
637:
528:
527:
524:
523:
479:
478:
466:
465:
404:
403:
302:
301:
201:
200:
96:TPD52 - orthologs
1944:
1915:
1908:
1901:
1869:
1862:
1853:
1823:
1794:
1761:(7062): 1173β8.
1748:
1719:
1701:
1676:
1666:
1656:
1630:
1620:
1595:
1566:
1537:
1507:
1478:
1440:
1411:
1382:
1361:
1322:
1321:
1292:
1286:
1285:
1248:
1239:
1238:
1231:
1225:
1224:
1215:(13): 2896β903.
1203:
1197:
1196:
1185:
1179:
1178:
1167:
1161:
1151:
1140:
1130:
1053:
1052:
1024:
1017:
1000:
960:
951:
915:
911:RefSeq (protein)
901:
861:
852:
808:
784:
765:
739:
720:
694:
675:
644:
534:
520:
511:
504:
497:
490:
475:
415:
413:Top expressed in
408:
377:endothelial cell
369:secondary oocyte
353:
351:Top expressed in
346:
325:
308:
298:
285:
274:
259:
252:
246:
235:
223:
207:
197:
184:
173:
158:
151:
145:
134:
120:
104:
98:
49:
42:
21:
1952:
1951:
1947:
1946:
1945:
1943:
1942:
1941:
1922:
1921:
1920:
1919:
1858:
1856:
1826:
1806:(11): 1355β63.
1797:
1751:
1722:
1679:
1633:
1598:
1569:
1540:
1510:
1481:
1443:
1423:(1β2): 149β56.
1414:
1385:
1364:
1335:
1331:
1329:Further reading
1326:
1325:
1294:
1293:
1289:
1250:
1249:
1242:
1233:
1232:
1228:
1205:
1204:
1200:
1187:
1186:
1182:
1169:
1168:
1164:
1152:
1143:
1131:
1122:
1117:
1093:
1062:View/Edit Mouse
1057:View/Edit Human
1020:
1013:
1010:Location (UCSC)
996:
992:
988:
982:
978:
974:
970:
966:
947:
943:
937:
933:
929:
925:
921:
897:
893:
889:
883:
879:
875:
871:
867:
848:
844:
840:
836:
830:
826:
822:
818:
814:
729:ENSG00000076554
622:
596:
570:
556:protein binding
516:
506:
505:
499:
498:
471:
462:
457:
453:
449:
445:
441:
437:
433:
429:
425:
411:
400:
395:
391:
387:
383:
379:
375:
371:
367:
363:
349:
293:
280:
272:
262:
261:
260:
253:
233:
210:Gene location (
192:
179:
171:
161:
160:
159:
152:
130:
107:Gene location (
58:
45:
38:
19:
12:
11:
5:
1950:
1948:
1940:
1939:
1934:
1924:
1923:
1918:
1917:
1910:
1903:
1895:
1892:
1891:
1870:
1855:
1854:
1836:(3): 798β806.
1824:
1795:
1749:
1720:
1692:(6): 1049β54.
1686:Int. J. Cancer
1677:
1647:(7): 2812β20.
1631:
1611:(5): 1589β94.
1596:
1567:
1538:
1508:
1479:
1441:
1412:
1383:
1362:
1344:(1β2): 171β4.
1332:
1330:
1327:
1324:
1323:
1287:
1240:
1226:
1198:
1180:
1162:
1141:
1119:
1118:
1116:
1113:
1092:
1089:
1069:
1068:
1065:
1064:
1059:
1049:
1048:
1042:
1041:
1038:
1037:
1035:
1033:
1026:
1025:
1018:
1011:
1007:
1006:
1003:
1002:
984:
983:
957:
954:
953:
939:
938:
912:
908:
907:
904:
903:
885:
884:
858:
855:
854:
832:
831:
805:
801:
800:
797:
796:
788:
787:
781:
778:
777:
769:
768:
762:
756:
755:
752:
751:
743:
742:
736:
733:
732:
724:
723:
717:
711:
710:
707:
706:
698:
697:
691:
688:
687:
679:
678:
672:
666:
665:
660:
655:
651:
650:
640:
639:
636:
635:
624:
623:
621:
620:
615:
610:
604:
602:
598:
597:
595:
594:
589:
584:
578:
576:
572:
571:
569:
568:
563:
558:
553:
547:
545:
541:
540:
530:
529:
526:
525:
522:
521:
513:
512:
487:
481:
480:
477:
476:
468:
467:
464:
463:
461:
460:
456:
452:
448:
444:
440:
439:lacrimal gland
436:
432:
431:salivary gland
428:
427:pyloric antrum
424:
420:
417:
416:
405:
402:
401:
399:
398:
394:
390:
386:
382:
378:
374:
370:
366:
362:
361:jejunal mucosa
358:
355:
354:
342:
341:
333:
322:
316:
315:
312:RNA expression
304:
303:
300:
299:
291:
287:
286:
278:
275:
270:
264:
263:
254:
247:
241:
237:
236:
231:
225:
224:
216:
215:
203:
202:
199:
198:
190:
186:
185:
177:
174:
169:
163:
162:
153:
146:
140:
136:
135:
128:
122:
121:
113:
112:
100:
99:
56:
52:
51:
43:
35:
34:
30:
29:
26:
25:
17:
13:
10:
9:
6:
4:
3:
2:
1949:
1938:
1935:
1933:
1930:
1929:
1927:
1916:
1911:
1909:
1904:
1902:
1897:
1896:
1890:
1888:
1884:
1880:
1876:
1871:
1868:
1864:
1859:
1851:
1847:
1843:
1839:
1835:
1831:
1825:
1821:
1817:
1813:
1809:
1805:
1801:
1796:
1792:
1788:
1784:
1780:
1776:
1772:
1768:
1764:
1760:
1756:
1750:
1746:
1742:
1738:
1734:
1731:(1): 152β65.
1730:
1726:
1725:Exp. Cell Res
1721:
1717:
1713:
1709:
1705:
1700:
1695:
1691:
1687:
1683:
1678:
1674:
1670:
1665:
1660:
1655:
1650:
1646:
1642:
1638:
1632:
1628:
1624:
1619:
1614:
1610:
1606:
1602:
1597:
1593:
1589:
1585:
1581:
1578:(3): 675β87.
1577:
1573:
1568:
1564:
1560:
1556:
1552:
1548:
1544:
1539:
1535:
1531:
1527:
1523:
1520:(1β3): 81β8.
1519:
1515:
1509:
1505:
1501:
1497:
1493:
1490:(1): 239β46.
1489:
1485:
1484:Exp. Cell Res
1480:
1476:
1472:
1468:
1464:
1460:
1456:
1453:(7): 873β81.
1452:
1448:
1442:
1438:
1434:
1430:
1426:
1422:
1418:
1413:
1409:
1405:
1401:
1397:
1394:(3): 523β32.
1393:
1389:
1384:
1380:
1376:
1373:(4): 741β51.
1372:
1368:
1363:
1359:
1355:
1351:
1347:
1343:
1339:
1334:
1333:
1328:
1319:
1315:
1311:
1307:
1304:(1β3): 81β8.
1303:
1299:
1291:
1288:
1283:
1279:
1275:
1271:
1267:
1263:
1260:(7): 873β81.
1259:
1255:
1247:
1245:
1241:
1236:
1230:
1227:
1222:
1218:
1214:
1210:
1202:
1199:
1194:
1190:
1184:
1181:
1176:
1172:
1166:
1163:
1159:
1155:
1150:
1148:
1146:
1142:
1138:
1134:
1129:
1127:
1125:
1121:
1114:
1112:
1110:
1106:
1102:
1098:
1090:
1088:
1086:
1083:
1079:
1075:
1063:
1058:
1054:
1050:
1047:
1043:
1036:
1034:
1031:
1027:
1023:
1019:
1016:
1012:
1008:
1001:
999:
995:
991:
985:
981:
977:
973:
969:
965:
961:
958:
952:
950:
946:
940:
936:
932:
928:
924:
920:
916:
913:
909:
902:
900:
896:
892:
886:
882:
878:
874:
870:
866:
862:
859:
853:
851:
847:
843:
839:
833:
829:
825:
821:
817:
813:
809:
806:
804:RefSeq (mRNA)
802:
795:
794:
789:
785:
782:
776:
775:
770:
766:
763:
761:
757:
750:
749:
744:
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1879:chromosome 8
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1572:J. Mol. Biol
1571:
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1091:Interactions
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998:NP_001344003
994:NP_001344002
990:NP_001344001
987:
976:NP_001020435
972:NP_001020434
968:NP_001020433
964:NP_001020432
945:NP_001274073
942:
935:NP_001274072
931:NP_001274071
927:NP_001274069
923:NP_001020424
919:NP_001020423
899:NM_001357074
895:NM_001357073
891:NM_001357072
888:
877:NM_001025264
873:NM_001025263
869:NM_001025262
865:NM_001025261
850:NM_001387780
846:NM_001387779
838:NM_001287144
835:
828:NM_001287143
824:NM_001287142
820:NM_001287140
816:NM_001025253
812:NM_001025252
791:
772:
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682:
662:
657:
335:
328:
55:External IDs
15:
1664:2434/602659
451:granulocyte
273:3|3 A1
193:80,231,232
180:80,034,745
33:Identifiers
1926:Categories
1605:Cancer Res
1209:Cancer Res
1160:, May 2017
1139:, May 2017
1115:References
435:left colon
339:(ortholog)
294:9,069,783
281:8,990,653
76:HomoloGene
1877:on human
1800:Leuk. Res
980:NP_033438
949:NP_005070
881:NM_009412
842:NM_005079
648:Orthologs
618:secretion
582:cytoplasm
84:GeneCards
1850:16631610
1820:16620967
1783:16189514
1745:16112108
1716:38845575
1708:15986428
1673:15576473
1627:14996714
1592:12963375
1563:11594751
1534:11549320
1514:Genomics
1504:10942595
1447:Oncogene
1388:Genomics
1367:Oncogene
1318:11549320
1298:Genomics
1254:Oncogene
1156:–
1135:–
1097:interact
1046:Wikidata
627:Sources:
397:duodenum
1791:4427026
1763:Bibcode
1475:9948136
1467:9484778
1437:9373149
1408:8812487
1379:8632896
1358:8125298
1282:9948136
1274:9484778
1221:7796418
1158:Ensembl
1137:Ensembl
1105:TPD52L1
1101:TPD52L2
1078:protein
760:UniProt
715:Ensembl
654:Species
633:QuickGO
314:pattern
172:8q21.13
40:Aliases
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1032:search
1030:PubMed
793:Q62393
774:P55327
670:Entrez
485:BioGPS
389:rectum
72:107749
64:604068
1881:is a
1787:S2CID
1712:S2CID
1641:Blood
1471:S2CID
1278:S2CID
1099:with
1082:TPD52
1076:is a
703:21985
663:Mouse
658:Human
629:Amigo
459:ileum
337:Mouse
330:Human
277:Start
212:Mouse
176:Start
109:Human
88:TPD52
80:38007
47:TPD52
24:TPD52
1883:stub
1875:gene
1846:PMID
1816:PMID
1779:PMID
1741:PMID
1704:PMID
1669:PMID
1623:PMID
1588:PMID
1559:PMID
1530:PMID
1500:PMID
1463:PMID
1433:PMID
1417:Gene
1404:PMID
1375:PMID
1354:PMID
1338:Gene
1314:PMID
1270:PMID
1217:PMID
1109:MAL2
1107:and
1085:gene
684:7163
320:Bgee
268:Band
229:Chr.
167:Band
126:Chr.
60:OMIM
1838:doi
1834:344
1808:doi
1771:doi
1759:437
1733:doi
1729:310
1694:doi
1690:117
1659:hdl
1649:doi
1645:105
1613:doi
1580:doi
1576:332
1551:doi
1547:288
1522:doi
1492:doi
1488:259
1455:doi
1425:doi
1421:200
1396:doi
1346:doi
1342:138
1306:doi
1262:doi
290:End
189:End
92:OMA
68:MGI
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