Knowledge (XXG)

TSPAN3

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242: 219: 116: 141: 493: 500: 248: 147: 2007: 1493: 255: 154: 1927: 1987: 1161:"Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries" 1486: 678: 659: 77: 1723: 1718: 2076: 1471: 2052: 2071: 1479: 1090: 1072: 1690: 1447: 1407:"Activation of globin gene expression by cDNAs from induced K562 cells. Evidence for involvement of ferritin in globin gene expression" 241: 894: 901: 1194:
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network".
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The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the
848: 797: 1227: 89: 1319:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" 877: 856: 852: 822: 801: 793: 492: 1428: 1393: 1358: 1305: 1270: 1219: 1182: 1147: 37: 2022: 1906: 1901: 1846: 1836: 1831: 1821: 1816: 1811: 1791: 1130:
Berditchevski F (2002). "Complexes of tetraspanins with integrins: more than meets the eye".
1932: 1761: 1741: 1648: 1643: 1638: 1633: 1628: 1623: 1613: 1603: 1598: 1588: 1583: 1506: 1418: 1383: 1348: 1338: 1295: 1260: 1252: 1211: 1172: 1139: 499: 334: 265: 209: 164: 85: 1618: 1593: 1545: 1540: 1010: 1006: 309: 1334: 1207: 1002: 1423: 1406: 1388: 1371: 1353: 1318: 1265: 1240: 593: 588: 572: 567: 562: 557: 541: 2065: 2018: 528: 69: 1518: 1231: 1009:
sites has been found for this gene. Two alternative transcripts encoding different
983: 327: 106: 93: 1871: 1733: 1095:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
998: 979: 965: 410: 1954: 1937: 1535: 1177: 1160: 987: 226: 123: 73: 1372:"Sequences and expression of six new members of the tetraspanin/TM4SF family" 1964: 1284:"Complete sequencing and characterization of 21,243 full-length human cDNAs" 1143: 623: 470: 348: 293: 280: 192: 179: 81: 1362: 1343: 1309: 1274: 1223: 1186: 1151: 997:
events that play a role in the regulation of cell development, activation,
1432: 1397: 941: 936: 1922: 1527: 925: 768: 749: 1215: 1896: 1891: 1851: 1841: 1826: 1806: 1801: 1796: 1786: 1502: 1256: 957: 735: 690: 1781: 1776: 1771: 1766: 1756: 1746: 1658: 1514: 909: 645: 2006: 1300: 1283: 1947: 1942: 1856: 1608: 1578: 1573: 961: 608: 604: 2014: 1974: 1969: 1886: 1876: 1866: 1861: 1671: 1568: 1550: 972: 508: 61: 1475: 1881: 1317:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
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proteins that are characterized by the presence of four
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Gerhard DS, Wagner L, Feingold EA, et al. (2004).
482: 1915: 1732: 1709: 1657: 1559: 1526: 870: 841: 815: 786: 1282:Ota T, Suzuki Y, Nishikawa T, et al. (2004). 1159:Otsuki T, Ota T, Nishikawa T, et al. (2007). 1051: 1049: 1047: 1030: 1028: 1026: 264: 163: 1928:LDL-receptor-related protein-associated protein 1056:GRCm38: Ensembl release 89: ENSMUSG00000032324 2046: 1487: 8: 1035:GRCh38: Ensembl release 89: ENSG00000140391 2053: 2039: 1494: 1480: 1472: 619: 524: 305: 204: 101: 1724:Pulmonary surfactant-associated protein C 1719:Pulmonary surfactant-associated protein B 1422: 1387: 1352: 1342: 1299: 1264: 1176: 1106: 1104: 1022: 589:cell surface receptor signaling pathway 48:, TM4-A, TM4SF8, TSPAN-3, tetraspanin 3 18: 1988:other cell membrane protein disorders 563:integral component of plasma membrane 269: 230: 225: 168: 127: 122: 7: 2003: 2001: 1691:Myelin oligodendrocyte glycoprotein 1370:Todd SC, Doctor VS, Levy S (1998). 1112:"Entrez Gene: TSPAN3 tetraspanin 3" 2025:. You can help Knowledge (XXG) by 982:family. Most of these members are 867: 838: 812: 783: 759: 740: 714: 695: 669: 650: 487: 433:central gray substance of midbrain 405: 343: 322: 14: 2005: 498: 491: 453:dorsomedial hypothalamic nucleus 253: 246: 240: 217: 152: 145: 139: 114: 2077:Human chromosome 15 gene stubs 1960:Phospholipid transfer proteins 1696:Myelin-associated glycoprotein 558:integral component of membrane 509:More reference expression data 471:More reference expression data 1: 1424:10.1016/S0021-9258(19)47409-7 1389:10.1016/s0167-4781(98)00087-6 421:vestibular sensory epithelium 238: 137: 16:Protein-coding gene in humans 2072:Genes on human chromosome 15 1323:Proc. Natl. Acad. Sci. U.S.A 425:Epithelium of choroid plexus 1452:human gene location in the 429:nucleus of stria terminalis 2093: 2000: 1679:Myelin proteolipid protein 1464:human gene details in the 1405:Wu YJ, Noguchi CT (1991). 1983: 1091:"Mouse PubMed Reference:" 1073:"Human PubMed Reference:" 940: 935: 931: 924: 908: 889: 874: 845: 834: 819: 790: 779: 766: 762: 747: 743: 734: 721: 717: 702: 698: 689: 676: 672: 657: 653: 644: 629: 622: 618: 602: 527: 523: 506: 490: 481: 468: 417: 408: 359:bronchial epithelial cell 355: 346: 316: 308: 304: 287: 274: 237: 216: 207: 203: 186: 173: 136: 113: 104: 100: 55: 52: 42: 35: 30: 26: 21: 895:Chr 15: 77.04 – 77.08 Mb 395:external globus pallidus 1178:10.1093/dnares/12.2.117 1144:10.1242/jcs.114.23.4143 1005:. The use of alternate 902:Chr 9: 56.04 – 56.07 Mb 363:mucosa of sigmoid colon 1376:Biochim. Biophys. Acta 1344:10.1073/pnas.242603899 437:ventral tegmental area 1511:Cell surface receptor 1013:have been described. 993:The proteins mediate 568:extracellular exosome 387:palpebral conjunctiva 130:Chromosome 15 (human) 1711:Pulmonary surfactant 1667:Myelin basic protein 1561:Membrane-spanning 4A 232:Chromosome 9 (mouse) 1701:Myelin protein zero 1466:UCSC Genome Browser 1454:UCSC Genome Browser 1335:2002PNAS...9916899M 1216:10.1038/nature04209 1208:2005Natur.437.1173R 995:signal transduction 457:superior colliculus 2013:This article on a 1257:10.1101/gr.2596504 1138:(Pt 23): 4143–51. 724:ENSMUSG00000032324 594:biological process 582:Biological process 551:Cellular component 542:molecular function 535:Molecular function 391:right uterine tube 94:TSPAN3 - orthologs 2034: 2033: 1995: 1994: 1507:membrane proteins 1329:(26): 16899–903. 951: 950: 947: 946: 920: 919: 885: 884: 864: 863: 830: 829: 809: 808: 775: 774: 756: 755: 730: 729: 711: 710: 685: 684: 666: 665: 614: 613: 519: 518: 515: 514: 477: 476: 464: 463: 402: 401: 375:corpus epididymis 300: 299: 199: 198: 2084: 2055: 2048: 2041: 2009: 2002: 1496: 1489: 1482: 1473: 1436: 1426: 1417:(26): 17566–72. 1401: 1391: 1366: 1356: 1346: 1313: 1303: 1278: 1268: 1235: 1202:(7062): 1173–8. 1190: 1180: 1155: 1116: 1115: 1108: 1099: 1098: 1087: 1081: 1080: 1069: 1063: 1053: 1042: 1032: 933: 932: 904: 897: 880: 868: 859: 839: 835:RefSeq (protein) 825: 813: 804: 784: 760: 741: 715: 696: 670: 651: 620: 525: 511: 502: 495: 488: 473: 413: 411:Top expressed in 406: 383:caput epididymis 367:ventricular zone 351: 349:Top expressed in 344: 323: 306: 296: 283: 272: 257: 250: 244: 233: 221: 205: 195: 182: 171: 156: 149: 143: 132: 118: 102: 96: 47: 40: 19: 2092: 2091: 2087: 2086: 2085: 2083: 2082: 2081: 2062: 2061: 2060: 2059: 1998: 1996: 1991: 1979: 1933:Neurofibromin 2 1916:Other/ungrouped 1911: 1728: 1705: 1653: 1555: 1522: 1500: 1444: 1439: 1404: 1369: 1316: 1281: 1251:(10B): 2121–7. 1238: 1193: 1158: 1129: 1125: 1123:Further reading 1120: 1119: 1110: 1109: 1102: 1089: 1088: 1084: 1071: 1070: 1066: 1054: 1045: 1033: 1024: 1019: 1007:polyadenylation 942:View/Edit Mouse 937:View/Edit Human 900: 893: 890:Location (UCSC) 876: 855: 851: 847: 821: 800: 796: 792: 705:ENSG00000140391 598: 577: 546: 507: 497: 496: 469: 460: 455: 451: 447: 443: 439: 435: 431: 427: 423: 409: 398: 393: 389: 385: 381: 377: 373: 369: 365: 361: 347: 291: 278: 270: 260: 259: 258: 251: 231: 208:Gene location ( 190: 177: 169: 159: 158: 157: 150: 128: 105:Gene location ( 56: 43: 36: 17: 12: 11: 5: 2090: 2088: 2080: 2079: 2074: 2064: 2063: 2058: 2057: 2050: 2043: 2035: 2032: 2031: 2010: 1993: 1992: 1984: 1981: 1980: 1978: 1977: 1972: 1967: 1962: 1957: 1952: 1951: 1950: 1945: 1935: 1930: 1925: 1919: 1917: 1913: 1912: 1910: 1909: 1904: 1899: 1894: 1889: 1884: 1879: 1874: 1869: 1864: 1859: 1854: 1849: 1844: 1839: 1834: 1829: 1824: 1819: 1814: 1809: 1804: 1799: 1794: 1789: 1784: 1779: 1774: 1769: 1764: 1759: 1754: 1749: 1744: 1738: 1736: 1730: 1729: 1727: 1726: 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1463: 1462: 1458: 1455: 1451: 1450: 1446: 1445: 1441: 1434: 1430: 1425: 1420: 1416: 1412: 1411:J. Biol. Chem 1408: 1403: 1399: 1395: 1390: 1385: 1381: 1377: 1373: 1368: 1364: 1360: 1355: 1350: 1345: 1340: 1336: 1332: 1328: 1324: 1320: 1315: 1311: 1307: 1302: 1297: 1293: 1289: 1285: 1280: 1276: 1272: 1267: 1262: 1258: 1254: 1250: 1246: 1242: 1237: 1233: 1229: 1225: 1221: 1217: 1213: 1209: 1205: 1201: 1197: 1192: 1188: 1184: 1179: 1174: 1171:(2): 117–26. 1170: 1166: 1162: 1157: 1153: 1149: 1145: 1141: 1137: 1133: 1128: 1127: 1122: 1113: 1107: 1105: 1101: 1096: 1092: 1086: 1083: 1078: 1074: 1068: 1065: 1061: 1057: 1052: 1050: 1048: 1044: 1040: 1036: 1031: 1029: 1027: 1023: 1016: 1014: 1012: 1008: 1004: 1000: 996: 991: 989: 985: 981: 976: 974: 971: 967: 963: 959: 955: 954:Tetraspanin-3 943: 938: 934: 930: 927: 923: 916: 914: 911: 907: 903: 899: 896: 892: 888: 881: 879: 873: 869: 866: 860: 858: 854: 850: 844: 840: 837: 833: 826: 824: 818: 814: 811: 805: 803: 799: 795: 789: 785: 782: 780:RefSeq (mRNA) 778: 771: 770: 765: 761: 758: 752: 751: 746: 742: 739: 737: 733: 726: 725: 720: 716: 713: 707: 706: 701: 697: 694: 692: 688: 681: 680: 675: 671: 668: 662: 661: 656: 652: 649: 647: 643: 640: 637: 635: 632: 628: 625: 621: 617: 610: 606: 601: 595: 592: 590: 587: 586: 584: 581: 580: 574: 571: 569: 566: 564: 561: 559: 556: 555: 553: 550: 549: 543: 540: 539: 537: 534: 533: 530: 529:Gene ontology 526: 522: 510: 505: 501: 494: 489: 486: 484: 480: 472: 467: 456: 452: 448: 444: 440: 436: 432: 428: 424: 420: 419: 416: 412: 407: 404: 394: 390: 386: 382: 378: 374: 370: 366: 362: 358: 357: 354: 350: 345: 342: 341: 338: 336: 332: 330: 329: 325: 324: 321: 319: 315: 311: 307: 303: 295: 290: 286: 282: 277: 267: 263: 256: 249: 243: 236: 228: 224: 220: 215: 211: 206: 202: 194: 189: 185: 181: 176: 166: 162: 155: 148: 142: 135: 131: 125: 121: 117: 112: 108: 103: 99: 95: 91: 87: 83: 79: 75: 71: 67: 63: 59: 51: 46: 39: 34: 29: 25: 20: 2027:expanding it 2012: 1997: 1985: 1751: 1519:cytoskeleton 1509:(other than 1460: 1448: 1414: 1410: 1382:(1): 101–4. 1379: 1375: 1326: 1322: 1291: 1287: 1248: 1244: 1199: 1195: 1168: 1164: 1135: 1131: 1094: 1085: 1076: 1067: 992: 984:cell-surface 977: 969: 953: 952: 875: 849:NP_001161884 846: 820: 798:NM_001168412 791: 767: 748: 722: 703: 677: 658: 638: 633: 441:right kidney 333: 326: 53:External IDs 1734:Tetraspanin 1294:(1): 40–5. 1132:J. Cell Sci 988:hydrophobic 980:tetraspanin 292:56,072,761 279:56,039,009 191:77,083,984 178:77,041,404 31:Identifiers 2066:Categories 1938:Presenilin 1288:Nat. Genet 1245:Genome Res 1062:, May 2017 1041:, May 2017 1017:References 990:domains. 445:left colon 337:(ortholog) 271:9|9 B 74:HomoloGene 2017:on human 1986:see also 1965:Dysferlin 878:NP_062767 857:NP_944492 853:NP_005715 823:NM_019793 802:NM_005724 794:NM_198902 624:Orthologs 379:beta cell 82:GeneCards 1923:Calnexin 1528:Arrestin 1363:12477932 1310:14702039 1275:15489334 1224:16189514 1187:16303743 1152:11739647 1058:– 1037:– 1011:isoforms 1003:motility 960:that in 926:Wikidata 603:Sources: 573:membrane 1907:TSPAN34 1902:TSPAN33 1897:TSPAN32 1892:TSPAN31 1887:TSPAN30 1882:TSPAN29 1877:TSPAN28 1872:TSPAN27 1867:TSPAN26 1862:TSPAN25 1857:TSPAN24 1852:TSPAN23 1847:TSPAN22 1842:TSPAN21 1837:TSPAN20 1832:TSPAN19 1827:TSPAN18 1822:TSPAN17 1817:TSPAN16 1812:TSPAN15 1807:TSPAN14 1802:TSPAN13 1797:TSPAN12 1792:TSPAN11 1787:TSPAN10 1515:enzymes 1505:: cell 1503:Protein 1433:1840594 1398:9714763 1331:Bibcode 1232:4427026 1204:Bibcode 1165:DNA Res 1060:Ensembl 1039:Ensembl 968:by the 966:encoded 958:protein 736:UniProt 691:Ensembl 630:Species 609:QuickGO 449:saccule 312:pattern 170:15q24.3 70:1928098 38:Aliases 1782:TSPAN9 1777:TSPAN8 1772:TSPAN7 1767:TSPAN6 1762:TSPAN5 1757:TSPAN4 1752:TSPAN3 1747:TSPAN2 1742:TSPAN1 1659:Myelin 1649:MS4A18 1644:MS4A15 1639:MS4A14 1634:MS4A13 1629:MS4A12 1624:MS4A10 1614:MS4A8B 1604:MS4A6E 1599:MS4A6A 1589:MS4A4E 1584:MS4A4A 1517:, and 1461:TSPAN3 1449:TSPAN3 1431:  1396:  1361:  1354:139241 1351:  1308:  1273:  1266:528928 1263:  1230:  1222:  1196:Nature 1185:  1150:  999:growth 970:TSPAN3 962:humans 912:search 910:PubMed 769:Q9QY33 750:O60637 646:Entrez 483:BioGPS 371:rectum 86:TSPAN3 62:613134 45:TSPAN3 22:TSPAN3 2021:is a 1948:PSEN2 1943:PSEN1 1619:MS4A9 1609:MS4A7 1594:MS4A5 1579:MS4A3 1574:MS4A2 1569:MS4A1 1546:ARRB2 1541:ARRB1 1228:S2CID 956:is a 679:56434 660:10099 639:Mouse 634:Human 605:Amigo 335:Mouse 328:Human 275:Start 210:Mouse 174:Start 107:Human 78:21168 2023:stub 2015:gene 1975:OTOF 1970:STRC 1684:PLP1 1672:PMP2 1551:ARR3 1429:PMID 1394:PMID 1380:1399 1359:PMID 1306:PMID 1271:PMID 1220:PMID 1183:PMID 1148:PMID 1001:and 973:gene 318:Bgee 266:Band 227:Chr. 165:Band 124:Chr. 58:OMIM 1955:HFE 1536:SAG 1419:doi 1415:266 1384:doi 1349:PMC 1339:doi 1296:doi 1261:PMC 1253:doi 1212:doi 1200:437 1173:doi 1140:doi 1136:114 964:is 288:End 187:End 90:OMA 66:MGI 2068:: 1513:, 1427:. 1413:. 1409:. 1392:. 1378:. 1374:. 1357:. 1347:. 1337:. 1327:99 1325:. 1321:. 1304:. 1292:36 1290:. 1286:. 1269:. 1259:. 1249:14 1247:. 1243:. 1226:. 1218:. 1210:. 1198:. 1181:. 1169:12 1167:. 1163:. 1146:. 1134:. 1103:^ 1093:. 1075:. 1046:^ 1025:^ 975:. 607:/ 294:bp 281:bp 193:bp 180:bp 88:; 84:: 80:; 76:: 72:; 68:: 64:; 60:: 2054:e 2047:t 2040:v 2029:. 1521:) 1495:e 1488:t 1481:v 1468:. 1456:. 1435:. 1421:: 1400:. 1386:: 1365:. 1341:: 1333:: 1312:. 1298:: 1277:. 1255:: 1234:. 1214:: 1206:: 1189:. 1175:: 1154:. 1142:: 1114:. 1097:. 1079:. 212:) 109:) 92::

Index

Aliases
TSPAN3
OMIM
613134
MGI
1928098
HomoloGene
21168
GeneCards
TSPAN3
OMA
TSPAN3 - orthologs
Human
Chromosome 15 (human)
Chr.
Chromosome 15 (human)
Chromosome 15 (human)
Genomic location for TSPAN3
Genomic location for TSPAN3
Band
bp
bp
Mouse
Chromosome 9 (mouse)
Chr.
Chromosome 9 (mouse)
Genomic location for TSPAN3
Genomic location for TSPAN3
Band
bp

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