242:
219:
116:
141:
493:
500:
248:
147:
2007:
1493:
255:
154:
1927:
1987:
1161:"Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries"
1486:
678:
659:
77:
1723:
1718:
2076:
1471:
2052:
2071:
1479:
1090:
1072:
1690:
1447:
1407:"Activation of globin gene expression by cDNAs from induced K562 cells. Evidence for involvement of ferritin in globin gene expression"
241:
894:
901:
1194:
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network".
218:
1111:
1059:
1038:
1695:
140:
115:
1459:
1055:
1034:
57:
254:
153:
2045:
1678:
247:
146:
723:
65:
1241:"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)"
1959:
704:
2038:
1683:
1510:
129:
1710:
1666:
1560:
1330:
1203:
44:
1700:
1465:
1453:
994:
978:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the
848:
797:
1227:
89:
1319:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"
877:
856:
852:
822:
801:
793:
492:
1428:
1393:
1358:
1305:
1270:
1219:
1182:
1147:
37:
2022:
1906:
1901:
1846:
1836:
1831:
1821:
1816:
1811:
1791:
1130:
Berditchevski F (2002). "Complexes of tetraspanins with integrins: more than meets the eye".
1932:
1761:
1741:
1648:
1643:
1638:
1633:
1628:
1623:
1613:
1603:
1598:
1588:
1583:
1506:
1418:
1383:
1348:
1338:
1295:
1260:
1252:
1211:
1172:
1139:
499:
334:
265:
209:
164:
85:
1618:
1593:
1545:
1540:
1010:
1006:
309:
1334:
1207:
1002:
1423:
1406:
1388:
1371:
1353:
1318:
1265:
1240:
593:
588:
572:
567:
562:
557:
541:
2065:
2018:
528:
69:
1518:
1231:
1009:
sites has been found for this gene. Two alternative transcripts encoding different
983:
327:
106:
93:
1871:
1733:
1095:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1077:
National Center for
Biotechnology Information, U.S. National Library of Medicine
998:
979:
965:
410:
1954:
1937:
1535:
1177:
1160:
987:
226:
123:
73:
1372:"Sequences and expression of six new members of the tetraspanin/TM4SF family"
1964:
1284:"Complete sequencing and characterization of 21,243 full-length human cDNAs"
1143:
623:
470:
348:
293:
280:
192:
179:
81:
1362:
1343:
1309:
1274:
1223:
1186:
1151:
997:
events that play a role in the regulation of cell development, activation,
1432:
1397:
941:
936:
1922:
1527:
925:
768:
749:
1215:
1896:
1891:
1851:
1841:
1826:
1806:
1801:
1796:
1786:
1502:
1256:
957:
735:
690:
1781:
1776:
1771:
1766:
1756:
1746:
1658:
1514:
909:
645:
2006:
1300:
1283:
1947:
1942:
1856:
1608:
1578:
1573:
961:
608:
604:
2014:
1974:
1969:
1886:
1876:
1866:
1861:
1671:
1568:
1550:
972:
508:
61:
1475:
1881:
1317:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
986:
proteins that are characterized by the presence of four
317:
2026:
1239:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
482:
1915:
1732:
1709:
1657:
1559:
1526:
870:
841:
815:
786:
1282:Ota T, Suzuki Y, Nishikawa T, et al. (2004).
1159:Otsuki T, Ota T, Nishikawa T, et al. (2007).
1051:
1049:
1047:
1030:
1028:
1026:
264:
163:
1928:LDL-receptor-related protein-associated protein
1056:GRCm38: Ensembl release 89: ENSMUSG00000032324
2046:
1487:
8:
1035:GRCh38: Ensembl release 89: ENSG00000140391
2053:
2039:
1494:
1480:
1472:
619:
524:
305:
204:
101:
1724:Pulmonary surfactant-associated protein C
1719:Pulmonary surfactant-associated protein B
1422:
1387:
1352:
1342:
1299:
1264:
1176:
1106:
1104:
1022:
589:cell surface receptor signaling pathway
48:, TM4-A, TM4SF8, TSPAN-3, tetraspanin 3
18:
1988:other cell membrane protein disorders
563:integral component of plasma membrane
269:
230:
225:
168:
127:
122:
7:
2003:
2001:
1691:Myelin oligodendrocyte glycoprotein
1370:Todd SC, Doctor VS, Levy S (1998).
1112:"Entrez Gene: TSPAN3 tetraspanin 3"
2025:. You can help Knowledge (XXG) by
982:family. Most of these members are
867:
838:
812:
783:
759:
740:
714:
695:
669:
650:
487:
433:central gray substance of midbrain
405:
343:
322:
14:
2005:
498:
491:
453:dorsomedial hypothalamic nucleus
253:
246:
240:
217:
152:
145:
139:
114:
2077:Human chromosome 15 gene stubs
1960:Phospholipid transfer proteins
1696:Myelin-associated glycoprotein
558:integral component of membrane
509:More reference expression data
471:More reference expression data
1:
1424:10.1016/S0021-9258(19)47409-7
1389:10.1016/s0167-4781(98)00087-6
421:vestibular sensory epithelium
238:
137:
16:Protein-coding gene in humans
2072:Genes on human chromosome 15
1323:Proc. Natl. Acad. Sci. U.S.A
425:Epithelium of choroid plexus
1452:human gene location in the
429:nucleus of stria terminalis
2093:
2000:
1679:Myelin proteolipid protein
1464:human gene details in the
1405:Wu YJ, Noguchi CT (1991).
1983:
1091:"Mouse PubMed Reference:"
1073:"Human PubMed Reference:"
940:
935:
931:
924:
908:
889:
874:
845:
834:
819:
790:
779:
766:
762:
747:
743:
734:
721:
717:
702:
698:
689:
676:
672:
657:
653:
644:
629:
622:
618:
602:
527:
523:
506:
490:
481:
468:
417:
408:
359:bronchial epithelial cell
355:
346:
316:
308:
304:
287:
274:
237:
216:
207:
203:
186:
173:
136:
113:
104:
100:
55:
52:
42:
35:
30:
26:
21:
895:Chr 15: 77.04 – 77.08 Mb
395:external globus pallidus
1178:10.1093/dnares/12.2.117
1144:10.1242/jcs.114.23.4143
1005:. The use of alternate
902:Chr 9: 56.04 – 56.07 Mb
363:mucosa of sigmoid colon
1376:Biochim. Biophys. Acta
1344:10.1073/pnas.242603899
437:ventral tegmental area
1511:Cell surface receptor
1013:have been described.
993:The proteins mediate
568:extracellular exosome
387:palpebral conjunctiva
130:Chromosome 15 (human)
1711:Pulmonary surfactant
1667:Myelin basic protein
1561:Membrane-spanning 4A
232:Chromosome 9 (mouse)
1701:Myelin protein zero
1466:UCSC Genome Browser
1454:UCSC Genome Browser
1335:2002PNAS...9916899M
1216:10.1038/nature04209
1208:2005Natur.437.1173R
995:signal transduction
457:superior colliculus
2013:This article on a
1257:10.1101/gr.2596504
1138:(Pt 23): 4143–51.
724:ENSMUSG00000032324
594:biological process
582:Biological process
551:Cellular component
542:molecular function
535:Molecular function
391:right uterine tube
94:TSPAN3 - orthologs
2034:
2033:
1995:
1994:
1507:membrane proteins
1329:(26): 16899–903.
951:
950:
947:
946:
920:
919:
885:
884:
864:
863:
830:
829:
809:
808:
775:
774:
756:
755:
730:
729:
711:
710:
685:
684:
666:
665:
614:
613:
519:
518:
515:
514:
477:
476:
464:
463:
402:
401:
375:corpus epididymis
300:
299:
199:
198:
2084:
2055:
2048:
2041:
2009:
2002:
1496:
1489:
1482:
1473:
1436:
1426:
1417:(26): 17566–72.
1401:
1391:
1366:
1356:
1346:
1313:
1303:
1278:
1268:
1235:
1202:(7062): 1173–8.
1190:
1180:
1155:
1116:
1115:
1108:
1099:
1098:
1087:
1081:
1080:
1069:
1063:
1053:
1042:
1032:
933:
932:
904:
897:
880:
868:
859:
839:
835:RefSeq (protein)
825:
813:
804:
784:
760:
741:
715:
696:
670:
651:
620:
525:
511:
502:
495:
488:
473:
413:
411:Top expressed in
406:
383:caput epididymis
367:ventricular zone
351:
349:Top expressed in
344:
323:
306:
296:
283:
272:
257:
250:
244:
233:
221:
205:
195:
182:
171:
156:
149:
143:
132:
118:
102:
96:
47:
40:
19:
2092:
2091:
2087:
2086:
2085:
2083:
2082:
2081:
2062:
2061:
2060:
2059:
1998:
1996:
1991:
1979:
1933:Neurofibromin 2
1916:Other/ungrouped
1911:
1728:
1705:
1653:
1555:
1522:
1500:
1444:
1439:
1404:
1369:
1316:
1281:
1251:(10B): 2121–7.
1238:
1193:
1158:
1129:
1125:
1123:Further reading
1120:
1119:
1110:
1109:
1102:
1089:
1088:
1084:
1071:
1070:
1066:
1054:
1045:
1033:
1024:
1019:
1007:polyadenylation
942:View/Edit Mouse
937:View/Edit Human
900:
893:
890:Location (UCSC)
876:
855:
851:
847:
821:
800:
796:
792:
705:ENSG00000140391
598:
577:
546:
507:
497:
496:
469:
460:
455:
451:
447:
443:
439:
435:
431:
427:
423:
409:
398:
393:
389:
385:
381:
377:
373:
369:
365:
361:
347:
291:
278:
270:
260:
259:
258:
251:
231:
208:Gene location (
190:
177:
169:
159:
158:
157:
150:
128:
105:Gene location (
56:
43:
36:
17:
12:
11:
5:
2090:
2088:
2080:
2079:
2074:
2064:
2063:
2058:
2057:
2050:
2043:
2035:
2032:
2031:
2010:
1993:
1992:
1984:
1981:
1980:
1978:
1977:
1972:
1967:
1962:
1957:
1952:
1951:
1950:
1945:
1935:
1930:
1925:
1919:
1917:
1913:
1912:
1910:
1909:
1904:
1899:
1894:
1889:
1884:
1879:
1874:
1869:
1864:
1859:
1854:
1849:
1844:
1839:
1834:
1829:
1824:
1819:
1814:
1809:
1804:
1799:
1794:
1789:
1784:
1779:
1774:
1769:
1764:
1759:
1754:
1749:
1744:
1738:
1736:
1730:
1729:
1727:
1726:
1721:
1715:
1713:
1707:
1706:
1704:
1703:
1698:
1693:
1688:
1687:
1686:
1676:
1675:
1674:
1663:
1661:
1655:
1654:
1652:
1651:
1646:
1641:
1636:
1631:
1626:
1621:
1616:
1611:
1606:
1601:
1596:
1591:
1586:
1581:
1576:
1571:
1565:
1563:
1557:
1556:
1554:
1553:
1548:
1543:
1538:
1532:
1530:
1524:
1523:
1501:
1499:
1498:
1491:
1484:
1476:
1470:
1469:
1457:
1443:
1442:External links
1440:
1438:
1437:
1402:
1367:
1314:
1301:10.1038/ng1285
1279:
1236:
1191:
1156:
1126:
1124:
1121:
1118:
1117:
1100:
1082:
1064:
1043:
1021:
1020:
1018:
1015:
949:
948:
945:
944:
939:
929:
928:
922:
921:
918:
917:
915:
913:
906:
905:
898:
891:
887:
886:
883:
882:
872:
871:
865:
862:
861:
843:
842:
836:
832:
831:
828:
827:
817:
816:
810:
807:
806:
788:
787:
781:
777:
776:
773:
772:
764:
763:
757:
754:
753:
745:
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738:
732:
731:
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719:
718:
712:
709:
708:
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682:
674:
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667:
664:
663:
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648:
642:
641:
636:
631:
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612:
611:
600:
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596:
591:
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583:
579:
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565:
560:
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552:
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545:
544:
538:
536:
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531:
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516:
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512:
504:
503:
485:
479:
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459:
458:
454:
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446:
442:
438:
434:
430:
426:
422:
418:
415:
414:
403:
400:
399:
397:
396:
392:
388:
384:
380:
376:
372:
368:
364:
360:
356:
353:
352:
340:
339:
331:
320:
314:
313:
310:RNA expression
302:
301:
298:
297:
289:
285:
284:
276:
273:
268:
262:
261:
252:
245:
239:
235:
234:
229:
223:
222:
214:
213:
201:
200:
197:
196:
188:
184:
183:
175:
172:
167:
161:
160:
151:
144:
138:
134:
133:
126:
120:
119:
111:
110:
98:
97:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
2089:
2078:
2075:
2073:
2070:
2069:
2067:
2056:
2051:
2049:
2044:
2042:
2037:
2036:
2030:
2028:
2024:
2020:
2019:chromosome 15
2016:
2011:
2008:
2004:
1999:
1990:
1989:
1982:
1976:
1973:
1971:
1968:
1966:
1963:
1961:
1958:
1956:
1953:
1949:
1946:
1944:
1941:
1940:
1939:
1936:
1934:
1931:
1929:
1926:
1924:
1921:
1920:
1918:
1914:
1908:
1905:
1903:
1900:
1898:
1895:
1893:
1890:
1888:
1885:
1883:
1880:
1878:
1875:
1873:
1870:
1868:
1865:
1863:
1860:
1858:
1855:
1853:
1850:
1848:
1845:
1843:
1840:
1838:
1835:
1833:
1830:
1828:
1825:
1823:
1820:
1818:
1815:
1813:
1810:
1808:
1805:
1803:
1800:
1798:
1795:
1793:
1790:
1788:
1785:
1783:
1780:
1778:
1775:
1773:
1770:
1768:
1765:
1763:
1760:
1758:
1755:
1753:
1750:
1748:
1745:
1743:
1740:
1739:
1737:
1735:
1731:
1725:
1722:
1720:
1717:
1716:
1714:
1712:
1708:
1702:
1699:
1697:
1694:
1692:
1689:
1685:
1682:
1681:
1680:
1677:
1673:
1670:
1669:
1668:
1665:
1664:
1662:
1660:
1656:
1650:
1647:
1645:
1642:
1640:
1637:
1635:
1632:
1630:
1627:
1625:
1622:
1620:
1617:
1615:
1612:
1610:
1607:
1605:
1602:
1600:
1597:
1595:
1592:
1590:
1587:
1585:
1582:
1580:
1577:
1575:
1572:
1570:
1567:
1566:
1564:
1562:
1558:
1552:
1549:
1547:
1544:
1542:
1539:
1537:
1534:
1533:
1531:
1529:
1525:
1520:
1516:
1512:
1508:
1504:
1497:
1492:
1490:
1485:
1483:
1478:
1477:
1474:
1467:
1463:
1462:
1458:
1455:
1451:
1450:
1446:
1445:
1441:
1434:
1430:
1425:
1420:
1416:
1412:
1411:J. Biol. Chem
1408:
1403:
1399:
1395:
1390:
1385:
1381:
1377:
1373:
1368:
1364:
1360:
1355:
1350:
1345:
1340:
1336:
1332:
1328:
1324:
1320:
1315:
1311:
1307:
1302:
1297:
1293:
1289:
1285:
1280:
1276:
1272:
1267:
1262:
1258:
1254:
1250:
1246:
1242:
1237:
1233:
1229:
1225:
1221:
1217:
1213:
1209:
1205:
1201:
1197:
1192:
1188:
1184:
1179:
1174:
1171:(2): 117–26.
1170:
1166:
1162:
1157:
1153:
1149:
1145:
1141:
1137:
1133:
1128:
1127:
1122:
1113:
1107:
1105:
1101:
1096:
1092:
1086:
1083:
1078:
1074:
1068:
1065:
1061:
1057:
1052:
1050:
1048:
1044:
1040:
1036:
1031:
1029:
1027:
1023:
1016:
1014:
1012:
1008:
1004:
1000:
996:
991:
989:
985:
981:
976:
974:
971:
967:
963:
959:
955:
954:Tetraspanin-3
943:
938:
934:
930:
927:
923:
916:
914:
911:
907:
903:
899:
896:
892:
888:
881:
879:
873:
869:
866:
860:
858:
854:
850:
844:
840:
837:
833:
826:
824:
818:
814:
811:
805:
803:
799:
795:
789:
785:
782:
780:RefSeq (mRNA)
778:
771:
770:
765:
761:
758:
752:
751:
746:
742:
739:
737:
733:
726:
725:
720:
716:
713:
707:
706:
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697:
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688:
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628:
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621:
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610:
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584:
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571:
569:
566:
564:
561:
559:
556:
555:
553:
550:
549:
543:
540:
539:
537:
534:
533:
530:
529:Gene ontology
526:
522:
510:
505:
501:
494:
489:
486:
484:
480:
472:
467:
456:
452:
448:
444:
440:
436:
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407:
404:
394:
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378:
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366:
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342:
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319:
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311:
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295:
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267:
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194:
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176:
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155:
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135:
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108:
103:
99:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
2027:expanding it
2012:
1997:
1985:
1751:
1519:cytoskeleton
1509:(other than
1460:
1448:
1414:
1410:
1382:(1): 101–4.
1379:
1375:
1326:
1322:
1291:
1287:
1248:
1244:
1199:
1195:
1168:
1164:
1135:
1131:
1094:
1085:
1076:
1067:
992:
984:cell-surface
977:
969:
953:
952:
875:
849:NP_001161884
846:
820:
798:NM_001168412
791:
767:
748:
722:
703:
677:
658:
638:
633:
441:right kidney
333:
326:
53:External IDs
1734:Tetraspanin
1294:(1): 40–5.
1132:J. Cell Sci
988:hydrophobic
980:tetraspanin
292:56,072,761
279:56,039,009
191:77,083,984
178:77,041,404
31:Identifiers
2066:Categories
1938:Presenilin
1288:Nat. Genet
1245:Genome Res
1062:, May 2017
1041:, May 2017
1017:References
990:domains.
445:left colon
337:(ortholog)
271:9|9 B
74:HomoloGene
2017:on human
1986:see also
1965:Dysferlin
878:NP_062767
857:NP_944492
853:NP_005715
823:NM_019793
802:NM_005724
794:NM_198902
624:Orthologs
379:beta cell
82:GeneCards
1923:Calnexin
1528:Arrestin
1363:12477932
1310:14702039
1275:15489334
1224:16189514
1187:16303743
1152:11739647
1058:–
1037:–
1011:isoforms
1003:motility
960:that in
926:Wikidata
603:Sources:
573:membrane
1907:TSPAN34
1902:TSPAN33
1897:TSPAN32
1892:TSPAN31
1887:TSPAN30
1882:TSPAN29
1877:TSPAN28
1872:TSPAN27
1867:TSPAN26
1862:TSPAN25
1857:TSPAN24
1852:TSPAN23
1847:TSPAN22
1842:TSPAN21
1837:TSPAN20
1832:TSPAN19
1827:TSPAN18
1822:TSPAN17
1817:TSPAN16
1812:TSPAN15
1807:TSPAN14
1802:TSPAN13
1797:TSPAN12
1792:TSPAN11
1787:TSPAN10
1515:enzymes
1505:: cell
1503:Protein
1433:1840594
1398:9714763
1331:Bibcode
1232:4427026
1204:Bibcode
1165:DNA Res
1060:Ensembl
1039:Ensembl
968:by the
966:encoded
958:protein
736:UniProt
691:Ensembl
630:Species
609:QuickGO
449:saccule
312:pattern
170:15q24.3
70:1928098
38:Aliases
1782:TSPAN9
1777:TSPAN8
1772:TSPAN7
1767:TSPAN6
1762:TSPAN5
1757:TSPAN4
1752:TSPAN3
1747:TSPAN2
1742:TSPAN1
1659:Myelin
1649:MS4A18
1644:MS4A15
1639:MS4A14
1634:MS4A13
1629:MS4A12
1624:MS4A10
1614:MS4A8B
1604:MS4A6E
1599:MS4A6A
1589:MS4A4E
1584:MS4A4A
1517:, and
1461:TSPAN3
1449:TSPAN3
1431:
1396:
1361:
1354:139241
1351:
1308:
1273:
1266:528928
1263:
1230:
1222:
1196:Nature
1185:
1150:
999:growth
970:TSPAN3
962:humans
912:search
910:PubMed
769:Q9QY33
750:O60637
646:Entrez
483:BioGPS
371:rectum
86:TSPAN3
62:613134
45:TSPAN3
22:TSPAN3
2021:is a
1948:PSEN2
1943:PSEN1
1619:MS4A9
1609:MS4A7
1594:MS4A5
1579:MS4A3
1574:MS4A2
1569:MS4A1
1546:ARRB2
1541:ARRB1
1228:S2CID
956:is a
679:56434
660:10099
639:Mouse
634:Human
605:Amigo
335:Mouse
328:Human
275:Start
210:Mouse
174:Start
107:Human
78:21168
2023:stub
2015:gene
1975:OTOF
1970:STRC
1684:PLP1
1672:PMP2
1551:ARR3
1429:PMID
1394:PMID
1380:1399
1359:PMID
1306:PMID
1271:PMID
1220:PMID
1183:PMID
1148:PMID
1001:and
973:gene
318:Bgee
266:Band
227:Chr.
165:Band
124:Chr.
58:OMIM
1955:HFE
1536:SAG
1419:doi
1415:266
1384:doi
1349:PMC
1339:doi
1296:doi
1261:PMC
1253:doi
1212:doi
1200:437
1173:doi
1140:doi
1136:114
964:is
288:End
187:End
90:OMA
66:MGI
2068::
1513:,
1427:.
1413:.
1409:.
1392:.
1378:.
1374:.
1357:.
1347:.
1337:.
1327:99
1325:.
1321:.
1304:.
1292:36
1290:.
1286:.
1269:.
1259:.
1249:14
1247:.
1243:.
1226:.
1218:.
1210:.
1198:.
1181:.
1169:12
1167:.
1163:.
1146:.
1134:.
1103:^
1093:.
1075:.
1046:^
1025:^
975:.
607:/
294:bp
281:bp
193:bp
180:bp
88:;
84::
80:;
76::
72:;
68::
64:;
60::
2054:e
2047:t
2040:v
2029:.
1521:)
1495:e
1488:t
1481:v
1468:.
1456:.
1435:.
1421::
1400:.
1386::
1365:.
1341::
1333::
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1298::
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1234:.
1214::
1206::
1189:.
1175::
1154:.
1142::
1114:.
1097:.
1079:.
212:)
109:)
92::
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