Talk:Methamphetamine

1447:"In the United States, methamphetamine hydrochloride, under the trade name Desoxyn, has been approved by the FDA for treating ADHD and obesity in both adults and children; however, the FDA also indicates that the limited therapeutic usefulness of methamphetamine should be weighed against the inherent risks associated with its use. To avoid toxicity and a risk of side effects, FDA guidelines recommend the initial dose of methamphetamine at doses 5-10mg/day for the treatment of ADHD in adults, and for the treatment of ADHD and obesity in children over six years of age. If a patient's therapeutic dose has not been reached, the dose may be increased by 5mg in weekly intervals until the optimum clinical response is found. The usual effective dose is around 20-25mg, however some people may find lower doses to be more therapeutic. "Methamphetamine should be administered at the lowest effective dosage, and dosage should be individually adjusted." If required, a daily dose may be divided into 2 effective doses. Methamphetamine is sometimes prescribed off label for narcolepsy and idiopathic hypersomnia in doses up to 60mg. In the United States, methamphetamine's levorotary form is available in some over-the-counter (OTC) nasal decongestant products. 2495:

Really? I mean come on lol, I know RLS sucks but people get that from SO many drugs. You do know RLS is mostly correlated with deficient dopamine levels right? Also no offense but virtually everything you said here pretty much goes without saying, it’s kind of just a reiteration of the same stuff people have said for a while now but it still doesn’t reconcile how the dependence is not physical. It’s still physical. We already know the presentation symptoms between these drugs. Like we know dude lol but come on you can’t really think that actually changes this issue. We don’t have to be experts to discern this. And I would gladly change or look into changing the “psychological dependence” article to a title such as “neurological dependence” but the terminology as of now makes no sense and is CLEARLY outdated. And yes credentialed people have pointed this out. But either way it’s a pretty obvious thing. I mean the title and what it implies is like straight out of the 80/90s or something. I even kinda wish there was even room for debate on this topic there really isn’t.. Sorry but there’s just no debatable angles to this. All drug dependencies are physical. There’s no way around that.

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drug/“scientific”/autodidact community in general. It really makes no sense and it treats neurological dependence like something which somehow isn’t “physical” merely because the symptoms are not somatic. The symptoms may not be “physical” but the dependency itself certainly is. Even coffee causes physical/neurological dependence. It seems to just be harping on the grossly outdated idea that stimulant dependencies are ‘fictive’ or just “in your head” with no palpable mechanisms which is clearly not the case. Meanwhile we have the other extreme going on with the cocaine article where people keep insisting on putting “high physical dependence” propensity which seems just as senseless. I can’t see any justifications for the meth/cocaine articles saying anything other than “moderate” in regards to the physical dependence sections. Maybe moderate - high at most. But just shamelessly saying straight up “high” or “none” is pretty ridiculous and essentially impossible to justify.

1436:"In the United States, methamphetamine hydrochloride, under the trade name Desoxyn, has been approved by the FDA for treating ADHD and obesity in both adults and children; however, the FDA also indicates that the limited therapeutic usefulness of methamphetamine should be weighed against the inherent risks associated with its use. To avoid toxicity, FDA guidelines recommend methamphetamine at doses 25mg/day for ADHD in adults and children over six years of age. Methamphetamine is sometimes prescribed off label for narcolepsy and idiopathic hypersomnia. In the United States, methamphetamine's levorotary form is available in some over-the-counter (OTC) nasal decongestant products." 3099:

Methamphetamine is a direct neurotoxin to DA neurons and current reviews of neuroimaging studies show that methamphetamine use correlates with neurotoxicity/neurodegeneration. Obviously, given (1) the common dosage patterns amongst methamphetamine users worldwide and (2) how irrelevant Desoxyn is relative to other USFDA-approved ADHD psychostimulants, meth use correlates with high-dose meth use in general. So, again, methamphetamine is clearly directly toxic at higher doses in humans, but that finding cannot be extended to lower (i.e., ~25 mg) doses.

182: 1506:"For treatment of children 6 years or older with a behavioral syndrome characterized by moderate to severe distractibility, short attention span, hyperactivity, emotional lability and impulsivity: an initial dose of 5 mg DESOXYN once or twice a day is recommended. Daily dosage may be raised in increments of 5 mg at weekly intervals until an optimum clinical response is achieved. The usual effective dose is 20 to 25 mg daily. The total daily dose may be given in two divided doses daily." 583: 1730:. I know I've read this in a handful of sources before, so it shouldn't be difficult to cite. If a comparison between amphetamine and methamphetamine enantiomers is included at all, then all 4 should probably be mentioned. Otherwise, I think cutting it seems justified. Also, while levomethamphetamine technically is a CNS stimulant, it's a fairly weak one in comparison to the other enantiomers, particularly considering that it's sold OTC in the United States as a nasal decongestant. 1186: 1168: 166: 1096: 1075: 308: 736: 715: 1029: 1004: 355: 574: 637: 2368: 616: 2821: 1595: 1401: 503: 403: 278: 1328: 936: 915: 825: 804: 3090:

transport chain enzyme subunits. I think it's also worth pointing out that any neurotoxicity is also potentiated by meth's activity at Sigma 1&2 receptors in human DA neurons, which increases DA release and elevates body temperature (NB activation of sigma receptors aren't inherently neurotoxic, but they potentiate meth's neurotoxicity because of several

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969.7 (psychostimulant poisoning) or E854.2 The study was based on a review of hospital records, so the doses used cannot be determined. People admitted into the study had to have been medically treated for either dependance, abuse or poisoning related to stimulants. What do you think the low dose vs high dose breakdown is for each of those categories?

835: 2995:. A UK study, zero meth use. All Amphetamine for the stimulant users. All amphetamine users took street amphetamine daily; 7 were also receiving a dextroamphetamine prescription (dose36.421.9 mg); none reported methamphetamine use. I'm not sure why the authors cited this. They do know that amphetamine and methamphetamine are different drugs right? 1243: 3147: 1668: 1527: 2886: 3195:, I owe you an apology. I distinctly remmeber adding that line to the source code, but, I've just checked the revision history for this article and there's no update from me on the 28th. So, I assume I simply forgot to click publish afterwards because of sleep deprivation and/or my medication having worn off. My bad. 2975:", but never quantify the "low dose" part of the title. Maybe there was some confusion during editing and that sentence got cut? They must have got that from somewhere though, so I read the cited papers and see to see what dose is considered low dose methamphetamine. There are eight papers cited in the section, 3032:

Is there anymore evidence that asserts that methamphetamine is toxic at low doses? I understand that there's going to be a greater prevalence of evidence covering high-dose users because methamphetamine is primarily a recreationally used drug. But, surely there needs to be some direct coverage of low

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Not low doses. The minimum dose to be admitted into the study is at least 5-10 times the therapeutic dose range. "METH abusers fulfilled Diagnostic and Statistical Manual of Mental Disorders IV criteria for METH dependence (average METH use of at least 0.25 gm /d, at least 5 d per week for at least 2

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Uhm... I'm pretty sure if the racemate is common name, then the dextro and levo enantiomers have the same common name. If you want to make a big fucking deal about this and draw other editors in simply because you don't like being reverted, then we can go back through the motions all over again. But,

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This is misleading, considering that a beginning dose, 25mg of methamphetamine, is NOT recommended by the FDA for the treatment of ADHD in adults, as well as the treatment of ADHD and obesity in children over six years of age without an observed clinical trial. A dose of 25mg is only "recommended" in

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Anyway, I was looking through the citations to better understand how and why methamphetamine is neurotoxic even at the doses indicated for ADHD, because they aren't as direct and straight forward as the imaging meta-analysis on ADHD amphetamine use in that article. I found two citations that seem to

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In the United States, methamphetamine hydrochloride, under the trade name Desoxyn, has been approved by the FDA for treating ADHD and obesity in both adults and children; however, the FDA also indicates that the limited therapeutic usefulness of methamphetamine should be weighed against the inherent

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for this to occur. Increases of sufficiently high DA via meth's participation in TAAR1- and CAMKII-mediated signaling cascades that phosphorylate DAT - and subsequent DA autoxidation can definitely amplify the neurotoxic effects of meth due DA quinones also having the capacity to mess with electron

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which allows it to permeate mitochondria in DA neurons and inhibit complexes II and III of the electron transport chain to trigger mitochondria depolarisation. Inhibition of those complexes from sufficient concentration of methamphetamine disrupts oxidative phosphorylation and ATP production (i.e.,

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Individuals aged at least 50 years were assigned to the methamphetamine group only if they had the following characteristics: (1) an ICD-9 diagnosis, in any diagnostic position, of 304.4 (amphetamine and other psychostimulant dependence), 305.7 (amphetamine or related acting sympathomimetic abuse),

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Also not that it really matters and it’s certainly not a competition but.. Those “opioid withdrawal symptoms“ you listed sound like some pretty rookie shit to me. I’ve had weed withdrawals that make those symptoms you listed look like a freaking trip to Disneyland. And I mean restless leg syndrome?

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itself is still clearly physical. I don’t understand why people have such a problem accepting that drug dependencies are either neurological or somatic (or even both) but there’s literally still no such thing as a “non-physical drug dependency”. That’s a pretty contradictory notion. I mean somebody

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Well I don’t see what that link has to do with dependence since that word isn’t even mentioned, nor do I see how it’s even a remotely reputable source. I bet I could scour that site and find dozens of bits of misinformation. I’ve found worse from “better sites” after all. At the end of the day many

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As a convention, most substituted amphetamines that are also prescription drugs don't use the INN, as is evident from the tracking category entries below. Their INNs are much less recognizable than the names derived from the amphetamine contraction (i.e., the common names that are used instead) in

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Accidentally said levoamphetamine instead of levomethamphetamine in my edit summary but I still don’t see how it’s relevant, particularly right there. Seems pretty random and I don’t see the point of comparing an isomer of methamphetamine to one of amphetamine when it’s not even comparing the same

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at doses 5-10mg/day for ADHD in adults and children over six years of age, and may be increased at weekly intervals of 5mg, up to 25mg/day, until optimum clinical response is found; the usual effective dose is around 20-25mg/day. Methamphetamine is sometimes prescribed off label for narcolepsy and

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I was debating whether I should've included that Desoxyn can be prescribed for Narcolepsy at up to 60mg, but I later realized that it was unnecessary to include the maximum dosages because the clinical period is probably the same for somebody being prescribed methamphetamine for narcolepsy. Thanks

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Reference states that, "Methamphetamine is used as a secondary treatment for attention deficit hyperactivity disorder (ADHD) in children over the age of six and for the short-term management of exogenous obesity. Used in this context, the FDA has approved the administration of methamphetamine at

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This article refers to methamphetamine as a neurotoxin, aka a direct neurotoxin. Before I continue, I just want to state that it's very clear that methamphetamine will induce neurodegeneration with chronic exposure to high doses. Not only is this evident from the generous amount of brain imaging

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Oh hey, a rat study. "The next day, rats received 4 injections at 2-hr intervals of either 0.9% saline or METH (10 mg/kg, s.c.). The rats were repeatedly injected with high doses (the LD50 of meth for rats is ~50mg/kg)." So after reading every single citation in the section, the lowest dose

2404:", per the lead of that article. All of those symptoms reflect a withdrawal syndrome associated with physical dependence. The symptoms I didn't quote from the lead - given that they're cognitive in nature - reflect psychological dependence. That being said, I don't see where in this article or 2348:

Also while I’m here, is there actually a source that says methamphetamine hydrochloride (HCl) is the crystallized form of methamphetamine because that sounds sort of contradictory to me but maybe I just don’t know enough about chemistry. I thought hydrochloric salts were literally removed from

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No mention of dose - Users recruited into the study came from treatment programs. MA and COC using participants were recruited from people treatment clinics in San Bernardino and Los Angeles counties in California. All of the participants for either drug group met DSM-IV criteria for abuse or

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In any event, all direct neurotoxins have a threshold dose they must meet in order to exert their relative toxic effect on the brain. What makes them direct neurotoxins is the fact that the substance engages in a direct pharmacological interaction with some aspect of a neuron that results in

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With all that said, I doubt we're going to get a clear answer on whether methamphetamine is neurotoxic or neuroprotective at the USFDA-approved dose range for Desoxyn pharmaceuticals through meta-analytic reviews of neuroimaging studies of low-dose users, a la amphetamine, any time soon.

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there's virtually no way you're going to convince everyone to keep the INN of that page the way it is given previous discussions about these article names. Also, using an INN for an enantiomer and a different common name for the racemate in their respective articles is just weird.

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Admittedly I’m not sure on that one about the hydrochloride form but I do know for a fact that physical dependence saying “none” is undoubtedly incorrect. This notion that only downers cause genuine physical dependencies is getting pretty old. Not just on Knowledge but in the

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As for the revised wording RE: meth nTox across the 2nd and 3rd editions of the Molecular Neuropharamcology textbook, that likely happened as a result of increasing questions of whether methamphetamine at lower doses is actually toxic to DA neurons, especially in humans.

1863:. The exceptions to using the INN and when to use a different common name as the pagename is explicitly stated on the MOS page, and the particular exceptions for methamphetamine and several amphetamine derivatives are stated as examples on the MOS page as well. To quote 2549:

People think “psychological dependence” means a fictive craving or just a mental desire. They don’t realize that it has neurological foundations and if they did they would admit that it’s physical, which it is. This is one of the things that’s not debatable.

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I'm not Seppi, but I feel the need to point that this article doesn't actually quantify the threshold exposure (i.e., dose) of methamphetamine that's necessary for DA neurotoxicity. The only mention of dose "range" is in the lead with the statement that

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mentioned is 250mg a day. I don't think anyone could call that a "low dose". I have no idea why the section was named the way it was when there is zero evidence to support it. It's unfortunate that seems to have confused a number of individuals.

3001:. The present study was designed to further our understanding of changes in brain function in humans that might result from chronic high dose use of MA after at least 3 months of abstinence. The study specifically recruited high dose users. 2863: 1858:

talk page archives and search for discussions about "INN" if you want to read the discussion about the use of the INN as the pagename and exceptions to this rule, but that's a bit unnecessary given what's actually written on

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s that they interact with; sigma-2 receptor activation can also trigger apoptotic cascades). That being said, the biggest contributor to neurodegeneration when using methamphetamine at relatively high doses is cerebral

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the occurrence of physical dependence is mentioned. They shouldn't state this because neither one - nor virtually any other psychostimulant drug - induces physical/somatic withdrawal symptoms after repeated use.

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Where is the arbitration or discussion that determined this should be the case? I checked the Manuals of Style, but couldn’t find such a supposed exception. If you could let me know, that would be appreciated.

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studies avaliable on meth recreational (high) and binge (very high) users, but also from the neurotoxic mechanisms methamphetamine has at high doses via EAAT inhibition and hyperthermia/BBB permeability.

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Based on autopsies, 11 out of 16 were reported to have methamphetamine intoxication as cause of death. I think we can all agree that a lethal dose of methamphetamine would not be considered a "low" dose?.

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mitochondrial dysfunction) which confers increased susceptibility to apoptosis. This is a direct pharmacological effect of the methamphetamine molecule in DA neurons and DA neurotransmission is not

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https://www.researchgate.net/publication/232545123_Comparative_Epidemiology_of_Dependence_on_Tobacco_Alcohol_Controlled_Substances_and_Inhalants_Basic_Findings_From_the_National_Comorbidity_Survey

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certain drugs (such as cocaine) to make them “smokable” (unless it’s a case by case thing), and from what I understand crystallized methamphetamine was first introduced specifically to be smoked.

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for the content in the destination pages and must not be deleted as long as the copies exist. For attribution and to access older versions of the copied text, please see the history links below.

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criteria. If you want to disseminate your personal opinion, you should do that in your own blog or somewhere else, and not infiltrate into every medical article pushing your personal opinion. --

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contains an updated list of of articles that don't follow this article title guideline and include the INN in the drugbox INN parameter; these articles are listed under the underscore section.

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a particular drug, I made that change, the CDC implies that these numbers represent the number of deaths with a particular drug, at least with opiates. See Understanding the Opiate Epidemic.

3040: 1806:. Just wanted to give you advance notice that I'll swap back the pagenames sometime in the near future. Since the page has fairly low traffic, this isn't a matter of any particular urgency. 1035: 1009: 3054:

Apologies in advanced for any grammatical errors; I finished writing this some time after my medication wore off and I pretty much lost all interest in proof reading by the end of it.

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Meanwhile, studies show Methamphetamine to have moderate addiction potential, 10-15%, which is the same addiction liability as Alcohol which has “Moderate (10-15%)” on its wiki page.

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be the most relevant for claims of low dose/direct neurotoxicity. The first one is" Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2nd ed.)" which states

2276:. I mean, one of those is an FA and this page is a GA. Obviously, the pagenames have been discussed ad nauseum. I just don't remember if they primarily took place on this page, 2392:- the more general concept - can entail either or both, depending on the drug. Physical/somatic withdrawal symptoms are easily observable/measurable. E.g., ethanol can induce 1278: 853: 195: 2989:. The subjects were included in the study if their average methamphetamine use involved at least 0.5 g/day, at least 5 days per week,for at least 2 years. No low doses here 2758:, not just methamphetamine. This nuance should be included if we write a section on overdose deaths. It should be tailored to incidents of only methamphetamine overdose. -- 2296:

want to read the relevant discussions, I'll link them for you later tonight or tomorrow. But again, I don't really see why you find it necessary given the fact that for

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Not trying to be a dick, but you need to understand there has been a lot of discussion about these article names in the past. It's not like MOS:PHARM is just ignored on

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Hmm. I tend to agree; that seems like a weird comparison without additional context, especially given that it's in the lead. Ranked by psychostimulant potency, it's:

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Granted, this kind of feels contradictory. If something is directly toxic, surely it should cause toxicity upon exposure. Say, if a 5mg Desoxyn tablet were given.

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dose/therapeutic dose range to be stating outright that methamphetamine is directly neurotoxic in the article. I feel like if anyone would know, it would be @

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Secondly, the source "Recent Advances in Methamphetamine Neurotoxicity Mechanisms and Its Molecular Pathophysiology". has a section in the paper titled "

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idiopathic hypersomnia. In the United States, methamphetamine's levorotary form is available in some over-the-counter (OTC) nasal decongestant products.

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idiopathic hypersomnia. In the United States, methamphetamine's levorotary form is available in some over-the-counter (OTC) nasal decongestant products.

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There is no evidence that Methamphetamine addiction potential is ‘very high’, and there is no source linked to back up that claim on this page.

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to be written into a project MOS, it has to be discussed ad nauseum on the talk page first. So, you already know you'll find a consensus there.

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I appreciate you being proactive about moving pages on drug articles to their INN pagename. There are, however, a handful of exceptions to the

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yeah that makes no sense because obviously the mechanisms which cause psychological symptoms are still very physical regardless, therefore the

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I think that information would be very useful for readers, so I think it should be included.Another editor recently moved the page

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type of isomer. Comparing potency of dextroamphetamine to dexromethamphetamine would make exponentially more sense (in the intro).

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I suggest that we revise the Medical section of methamphetamine to become more informative and to ensure maximum risk prevention.

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reliasmedia.com, nchrc.org, amegroups.org, consultant360.com, and chooser.crossref.org are not reliable sources.Interpreting

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If you want to conflate the two, that’s your prerogative. Everyone else in the world is still going to make the distinction.

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naming convention on drugs (see the first note), and you incidentally happened to come across one of those exceptions with

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methamphetamine is neurotoxic to human midbrain dopamine neurons and, to a lesser extent, serotonin neurons at high doses.

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English-speaking countries. As a rather extreme example, I doubt even 1% of the general population would even recognize

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https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=81bfc45f-c345-47d0-9fc9-77abe553b541&type=display

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It might be that opiates are perceived to be more lethal than methamphetamine or cocaine which is probably true.

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FDA guidelines recommend methamphetamine at doses 25mg/day for ADHD in adults and children over six years of age.

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dependence. I think it's safe to assume that most users in treatment for addiction were not low dose users.

2375:. Pure, unadulterated methamphetamine hydrochloride looks like a translucent white crystal, hence the name. 3192: 2042: 602: 531: 513: 354: 1647:

To avoid toxicity and risk of side effects, FDA guidelines recommend an initial dose of methamphetamine

222: 2940:"unlike cocaine and amphetamine, methamphetamine is directly neurotoxic to midbrain dopamine neurons." 2372: 2371:

This is the image we use to illustrate methamphetamine hydrochloride (crystal meth). Compare this to

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the treatment of ADHD (Or a child's obesity) after testing a patient's dose-responsive relationship.

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Association of Dopamine Transporter Reduction With Psychomotor Impairment in Methamphetamine Abusers

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To avoid toxicity and risk of side effects, FDA guidelines recommend initial dose of methamphetamine

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It doesn't matter what your opinion is. Knowledge articles are based on reliable sources that meet

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on Knowledge. If you would like to participate, please visit the project page, where you can join

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on Knowledge. If you would like to participate, please visit the project page, where you can join

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on Knowledge. If you would like to participate, please visit the project page, where you can join

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Hmmm... it seems that the category is still missing actually. Would you mind checking it again,

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Where’s this supposed “big fucking deal” you’re whining about? I was nothing but polite to you.

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Text has been copied to or from this article; see the list below. The source pages now serve to

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That’s methamphetamine, racemic, not enantiopure levmetamfetamine which is being referred to.

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Loss of Dopamine Transporters in Methamphetamine Abusers Recovers with Protracted Abstinence.

1488:" section for methamphetamine, there is a distressing error that claims, "To avoid toxicity, 3005:

Incidence of Parkinson’s disease among hospital patients with methamphetamine-use disorders.

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dependence is ALWAYS physical and that’s an inescapable fact. So this is clearly a misnomer.

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Stated within the Desoxyn Prescribing Information PDF, reference 24, and according to "",

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Here is a link to one such study that shows Methamphetamine’s 10-15% addiction liability:

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is literally just based on whether withdrawal symptoms are physical/somatic or cognitive.

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I also like how you improved the readability of the edit through the use of semicolons.

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Methamphetamine overdose deaths often involves polydrug abuse, involving various drug

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Hello. Requesting that the following category be added to this semi-protected page:

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Drugbox tracking category entries for pages that don't use their INN as the pagename

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However, I have read the third edition from 2015, which has revised this claim to

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can say what they want about the symptoms themselves but the dependence.. like the

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Cognitive function and nigrostriatal markers in abstinent methamphetamine abusers

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restless legs, nausea, vomiting, diarrhea, sweating, and an increased heart rate

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True, but I wouldn't expect to be immediately reverted by someone non-combative.

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This information should also be added to the pharmacology section on the page.

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Everyone else in the world? Nobody believes neurological doesn’t mean physical

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However, I have read the third edition from 2015, which has revised this claim

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This section is well reference by many reliable sources including the CDC.

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This article needs mentions and definitions of "super meth" and "P2P meth"

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Perseverative behavior in rats with methamphetamine-induced neurotoxicity.

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toxicity. Methamphetamine is a direct neurotoxin if only due its high

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I appreciate the quick fix. Thanks for updating my talk page as well!

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Cognitive Performance of Current Methamphetamine and Cocaine Abusers

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Change “Addiction liability” from Very High to Moderate (10-15%).

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History_and_culture_of_substituted_amphetamines#Illegal_synthesis

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Anyway, I've rectified this in the latest revision of the page.

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Knowledge level-5 vital articles in Biology and health sciences

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Methamphetamine Hcl =\= Crystal meth? Also physical dependence

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Category:Infobox drug articles with non-default infobox title

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Dextroamphetamine stronger stimulant than levomethamphetamine

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Reflection Impulsivity in Current and Former Substance Users

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for Knowledge's health content are defined in the guideline

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Brain serotonin transporter in human methamphetamine users

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and that when it is smoked it causes a massive release of

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Knowledge:WikiProject Psychoactive and Recreational Drugs

662:. To participate, help improve this article or visit the 173: 2893:: Methamphetamine have established addiction liability. 2678:

sources (such as stats, invidual case reports, etc.) is

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Knowledge vital articles in Biology and health sciences

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GA-Class vital articles in Biology and health sciences

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Knowledge Did you know articles that are good articles

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Thank you for your help. That is greatly appreciated.

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clinical publications about evidence-based medicine

2786:Although these statistics are reported as deaths 1869:A drug article should be titled according to its 1254:Knowledge:Identifying reliable sources (medicine) 506:A fact from this article appeared on Knowledge's 2792:https://www.cdc.gov/opioids/basics/epidemic.html 1038:, a project which is currently considered to be 656:, which aims to improve Knowledge's coverage of 57:for general discussion of the article's subject. 2926:Methamphetamine "direct" neurotoxicity validity 1377:History and culture of substituted amphetamines 1354:History and culture of substituted amphetamines 1036:WikiProject Psychoactive and Recreational Drugs 856:and that biomedical information in any article 2682:. Overdose information should be sourced from 1568:for catching that and shortening up the edit! 382:If it no longer meets these criteria, you can 854:Manual of Style for medicine-related articles 221: 181: 8: 3229:Knowledge articles that use American English 3021:years, at least2 weeks of METH abstinence).: 1056:Psychoactive and Recreational Drugs articles 2812:Semi-protected edit request on 7 March 2024 1586:Semi-protected edit request on 18 July 2023 1959: 1623:Reason for edit: Small grammatical error. 1392:Semi-protected edit request on 7 July 2023 1326: 1162: 1069: 998: 909: 798: 709: 610: 396: 349: 320:, which has its own spelling conventions ( 3129:page for details and sources. Thank you. 1764:. It would benefit a review from you. -- 1279:review articles from the past five years 1962: 1892: 1455: 1164: 1071: 1000: 911: 800: 711: 612: 3066: 3059: 2439:for the name reflecting the HCL salt. 2401: 1899: 1868: 1443:Methamphetamine < Uses < Medical 1432:Methamphetamine < Uses < Medical 3299:High-importance pharmacology articles 340:, this should not be changed without 207: 7: 3329:Mid-importance neuroscience articles 3041:2001:388:6080:84:44D5:6AD6:DCAC:9235 1473:The explanation for my edit request: 1307:Centre for Reviews and Dissemination 1101:This article is within the scope of 1034:This article is within the scope of 941:This article is within the scope of 846:This article is within the scope of 741:This article is within the scope of 642:This article is within the scope of 573: 571: 1047:Psychoactive and Recreational Drugs 1010:Psychoactive and Recreational Drugs 863:Knowledge talk:WikiProject Medicine 47:for discussing improvements to the 3289:High-importance chemicals articles 1200:. For more information, visit the 961:Knowledge:WikiProject Neuroscience 761:Knowledge:WikiProject Pharmacology 25: 3314:High-importance medicine articles 3304:WikiProject Pharmacology articles 2969:2.2. Long-Term Damage of Low Dose 1871:International Nonproprietary Name 1304:Other potential sources include: 964:Template:WikiProject Neuroscience 764:Template:WikiProject Pharmacology 375:. If you can improve it further, 3259:Knowledge level-5 vital articles 3145: 2884: 2819: 2123:Pfizer–BioNTech COVID-19 vaccine 1666: 1593: 1525: 1399: 1241: 1214:Knowledge:WikiProject Disability 1184: 1166: 1094: 1073: 1027: 1002: 934: 913: 858:use high-quality medical sources 833: 823: 802: 734: 713: 635: 614: 581: 572: 501: 401: 353: 306: 276: 69:Click here to start a new topic. 3354:WikiProject Disability articles 3339:High-importance Autism articles 3269:GA-Class level-5 vital articles 3127:monoaminergic activity enhancer 1854:I mean ... you could check the 1645:risks associated with its use. 1633:risks associated with its use. 1217:Template:WikiProject Disability 1145:This article has been rated as 981:This article has been rated as 892:This article has been rated as 781:This article has been rated as 692:This article has been rated as 672:Knowledge:WikiProject Chemicals 3324:GA-Class neuroscience articles 3319:All WikiProject Medicine pages 3294:GA-Class pharmacology articles 3239:Natural sciences good articles 2958:to midbrain dopamine neurons." 2078:Lutetium (177Lu) oxodotreotide 872:Knowledge:WikiProject Medicine 675:Template:WikiProject Chemicals 601:It is of interest to multiple 367:Natural sciences good articles 363:has been listed as one of the 1: 3074:It clearly is at higher doses 2806:03:40, 28 November 2023 (UTC) 2781:13:16, 27 November 2023 (UTC) 2750:15:09, 22 November 2023 (UTC) 2727:20:10, 22 November 2023 (UTC) 2713:19:04, 22 November 2023 (UTC) 2669:13:48, 22 November 2023 (UTC) 2649:01:54, 14 November 2023 (UTC) 2617:20:39, 13 November 2023 (UTC) 1973:3,4-Methylenedioxyamphetamine 1865:MOS:PHARM#Articles to use INN 1800:MOS:PHARM#Articles to use INN 1265:sources of information about 1119:and see a list of open tasks. 955:and see a list of open tasks. 875:Template:WikiProject Medicine 755:and see a list of open tasks. 66:Put new text under old text. 3349:GA-Class Disability articles 3244:Old requests for peer review 1125:Knowledge:WikiProject Autism 3344:WikiProject Autism articles 3284:GA-Class chemicals articles 3208:10:21, 19 August 2024 (UTC) 3187:19:27, 17 August 2024 (UTC) 3115:Protected page edit request 2842:to reactivate your request. 2830:has been answered. Set the 2023:Copper (64Cu) oxodotreotide 1900:Notable exceptions include 1725:dextromethamphetamine : --> 1616:to reactivate your request. 1604:has been answered. Set the 1500:doses of up to 25 mg/day." 1422:to reactivate your request. 1410:has been answered. Set the 1128:Template:WikiProject Autism 666:for details on the project. 527:The text of the entry was: 74:New to Knowledge? Welcome! 3370: 3309:GA-Class medicine articles 2591:18:24, 4 August 2023 (UTC) 2560:18:18, 4 August 2023 (UTC) 2545:18:13, 4 August 2023 (UTC) 2531:20:36, 3 August 2023 (UTC) 1151:project's importance scale 987:project's importance scale 898:project's importance scale 787:project's importance scale 698:project's importance scale 432:Featured article candidate 3200:Professional Crastination 3175:Professional Crastination 3163:04:40, 28 July 2024 (UTC) 3155:Professional Crastination 3139:19:57, 25 July 2024 (UTC) 3109:14:31, 28 June 2024 (UTC) 3101:Professional Crastination 2920:00:05, 8 March 2024 (UTC) 2895:Methamphetamine#Addictive 2878:22:06, 7 March 2024 (UTC) 2505:16:43, 29 July 2023 (UTC) 2476:16:49, 29 July 2023 (UTC) 2461:02:09, 22 July 2023 (UTC) 2431:02:03, 22 July 2023 (UTC) 2363:01:20, 22 July 2023 (UTC) 2322:03:16, 24 July 2023 (UTC) 2253:03:02, 24 July 2023 (UTC) 2239:02:39, 24 July 2023 (UTC) 2212:02:21, 24 July 2023 (UTC) 2198:02:09, 24 July 2023 (UTC) 1843:01:17, 24 July 2023 (UTC) 1828:21:00, 23 July 2023 (UTC) 1787:15:14, 22 July 2023 (UTC) 1752:01:43, 22 July 2023 (UTC) 1718:01:04, 22 July 2023 (UTC) 1697:03:00, 18 July 2023 (UTC) 1660:02:55, 18 July 2023 (UTC) 1179: 1144: 1089: 1022: 980: 929: 891: 818: 780: 729: 691: 630: 609: 554: 498: 399: 395: 104:Be welcoming to newcomers 33:Skip to table of contents 3334:GA-Class Autism articles 3087:necessary and sufficient 2386:psychological dependence 2380:The distinction between 2373:this google image search 2108:Moderna COVID-19 vaccine 2028:CureVac COVID-19 vaccine 1578:07:25, 8 July 2023 (UTC) 1557:01:06, 8 July 2023 (UTC) 1519:22:44, 7 July 2023 (UTC) 944:WikiProject Neuroscience 744:WikiProject Pharmacology 650:, a daughter project of 32: 3254:GA-Class vital articles 3234:Knowledge good articles 3049:09:31, 5 May 2024 (UTC) 2128:Recombinant factor VIIa 2083:Magnesium (medical use) 1726:dextroamphetamine : --> 1652:Seventeenyearoldchemist 1570:Seventeenyearoldchemist 1511:Seventeenyearoldchemist 1360:) on September 24, 2013 1194:is within the scope of 2376: 2298:basically any guidance 1383:) on December 31, 2013 1197:WikiProject Disability 535:is a highly addictive 99:avoid personal attacks 2370: 2043:Dibrospidium chloride 1727:levoamphetamine : --> 1480:Contained within the 967:neuroscience articles 767:pharmacology articles 653:WikiProject Chemistry 646:WikiProject Chemicals 588:level-5 vital article 529:Did you know ...that 373:good article criteria 270:Auto-archiving period 147:Find medical sources: 124:Neutral point of view 2153:Tetrahydrocannabinol 2058:Imidazole salicylate 1978:4-Hydroxyamphetamine 1877:is more appropriate. 1285:free review articles 1261:. Here are links to 849:WikiProject Medicine 489:Good article nominee 470:Good article nominee 338:relevant style guide 334:varieties of English 129:No original research 2655:Death from Overdose 2382:physical dependence 2274:levomethamphetamine 2148:Tetrahydrobiopterin 1804:levomethamphetamine 1758:levomethamphetamine 1728:levomethamphetmaine 1335:provide attribution 1220:Disability articles 336:. According to the 2686:sources that meet 2377: 1257:and are typically 1104:WikiProject Autism 678:chemicals articles 597:content assessment 407:Article milestones 153: 110:dispute resolution 71: 2846: 2845: 2398:opioid withdrawal 2266:dextroamphetamine 2165: 2164: 2038:Dextroamphetamine 1998:Bempegaldesleukin 1694: 1620: 1619: 1426: 1425: 1389: 1388: 1321: 1320: 1236: 1235: 1232: 1231: 1228: 1227: 1161: 1160: 1157: 1156: 1068: 1067: 1064: 1063: 997: 996: 993: 992: 908: 907: 904: 903: 878:medicine articles 797: 796: 793: 792: 708: 707: 704: 703: 566: 565: 562: 561: 463:December 26, 2008 444:December 10, 2006 391: 348: 347: 301: 300: 152:Source guidelines 151: 90:Assume good faith 67: 38: 37: 16:(Redirected from 3361: 3153: 3149: 3148: 2916: 2910: 2909: 2892: 2888: 2887: 2837: 2833: 2823: 2822: 2816: 2777: 2771: 2770: 2740: 2709: 2703: 2702: 2645: 2639: 2638: 2587: 2581: 2580: 2518: 2514: 2448: 2444: 2418: 2414: 2394:delirium tremens 2309: 2305: 2278:talk:amphetamine 2226: 2222: 2185: 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