Talk:Methamphetamine/Archive 5

199:"Brace yourself for a blowout of biblical proportions. Do yourself a favor.. While your standing there with the bottle still in your hand with your ears ringing so scared your afraid to look at your hand b/c your not sure you still have one. (This happened to me 3 times) When you realize your hand is still intact b/c its still holding the bottle with a gigantic fucking hole in it this is when you have roughly 3 minutes to grab a shitload of kitty litter before the lithium firework display starts. THUD THUD THUD THUD. Fire here, fire there. Oh shit.. now the sodium/potassium nitrate is on fire!!! Panic... throw water on it... j/k.. but I know ppl who freaked out and did just that. Long story short... one guy in particular was burnt so bad his gf took him to the ER b/c they were afraid of LE intervention calling 911. Guess what they came home too?? Punch line... What home!" 1377:

endless bureaucratic paper trail would have survived in the German archives - typical of the Wehrmacht was endless record keeping - including: endless lists of people who were to receive the drug on a regular basis, fixed distribution points for the public, a sophisticated logistical apparatus which would transport the drugs from depots to these distribution points; and if not that, at least an order from the central health authorities instructing physicians to prescribe the drug to their patients. Aside from an estimate of how many pervitin tablets were manufactured by the pharmaceutical company Temmler Werke, nothing has ever been found to substantiate this claim. In all, the German military did not receive many pills; certainly not enough to have the entire military high for the duration of a five and a half years war.

4843:

al., 2004). In addition, the brains of METH abusers show evidence of hyperintensities in white matter (Bae et al., 2006; Ernst et al., 2000), decreases in the neuronal marker, N-acetylaspartate (Ernst et al., 2000; Sung et al., 2007), reductions in a marker of metabolic integrity, creatine (Sekine et al., 2002) and increases in a marker of glial activation, myoinositol (Chang et al., 2002; Ernst et al., 2000; Sung et al., 2007; Yen et al., 1994). Elevated choline levels, which are indicative of increased cellular membrane synthesis and turnover are also evident in the frontal gray matter of METH abusers (Ernst et al., 2000; Salo et al., 2007; Taylor et al., 2007).

2903: 4326:

discussed in concert, at minimum.) Astute viewers of "Breaking Bad" (the popularity of which has no doubt greatly increased traffic to this page!) will realize that the different processes are a key plot point of the show. Those coming to Wikipeia hungering to understand more will be sadly disappointed by the dryly scientific and technical article they encounter here. IF the cultural (i.e., "street" aspects of the drug are discussed elsewhere, then THAT link needs to be made MUCH more prominent. It was not discernable in my quick scan of the disambig. page!) Anhow, a few other specific comments:

1627: 361:

ever-expanding child's chemistry set of compounds now banned to the public because somehow they can be used to make it. I'm sure there are better sources; my philosophy is that one source is better than no source, two are better than one, three... etc. It's very hard to look up technical details about something until you know what you're looking for. So for example, at the moment I don't understand why using mercuric chloride would lead to environmental lead contamination - but a source says it, and until proven wrong my guess is that there's some reason.

2877: 2890: 1385:

Whereas the military limited the use of pervitin the fall of 1941, for civilians, dolantin (an opiate), pervitin (crystal meth), and benzedrine (‘bennies,’ an American amphetamine popular at the time) were included in the sixth amendment of the drug law a few months earlier on 21 June 1941. The reason, according to Oberregierungsrat Kärber of the Ministry of Health, was the addictive nature of the drugs, not pilot experiences in the Luftwaffe.

31: 1366:

It was widely distributed across rank and division, from elite forces to tank crews and aircraft personnel, with many millions of tablets being distributed throughout the war. Its use by German Panzer crews also led to it being known as "Panzerschokolade" ("Panzer chocolate" or "tankers' chocolate"). More than 35 million three-milligram doses of Pervitin were manufactured for the German army and air force between April and July 1940.

1373:

widely distributed across rank and division, from elite forces to tank crews and aircraft personnel, with many millions of tablets being distributed throughout the war. Its use by German Panzer crews also led to it being known as "Panzerschokolade" ("Panzer chocolate" or "tankers' chocolate"). More than 35 million three-milligram doses of Pervitin were manufactured for the German army and air force between April and July 1940.

772:"Over 20% of people addicted to methamphetamine develop a long-lasting psychosis resembling schizophrenia after stopping methamphetamine. The condition persists for longer than 6 months and is often treatment resistant." This is false, looking at the source it says of those who develop psychosis from MA 20% get those kinds of symptoms, not that 20% of addicts do. Very big difference, someone please change. 1540: 1334: 1264: 1084: 965: 812: 4322:

Knowledge to reach its readers. I can ASSURE you that 95% (if not more) of the people coming to Knowledge to read more on "meth" are interested in it as a street drug and the history related to it's rise as such. Case in point: I went to Knowledge to research "meth" after I started reading the excellent NF book, "Methland: The Death and Life of an American Small Town," by Nick Reding.

2019:

after the split. The idea was to omit everything that didn't fit well into that layout and move it to a new page, since one page is simply too big for all that information. Consequently, there would more or less be 2 pages on the same topic from different perspectives. A small amount of redundancy would therefore be inevitable, but it would be a lot less redundant than, for example,

4383:(2) As noted in the censored comments in the lead, the citations are coupled to the equivalent statements in the body of the article - every section except contraindications was summarized. As for the more controversial statements related to adverse effects and amphetamine vs methamphetamine, the associated text (including refs) from the body is the following quotes. 2823: 4836:

prefrontal cortex, and the caudate-putamen (McCann et al., 1998, 2008; Sekine et al., 2003; Volkow et al., 2001a, 2001c). The density of serotonin transporters (5-HTT) is also decreased in the midbrain, caudate, putamen, hypothalamus, thalamus, the orbitofrontal, temporal, and cingulate cortices of METH-dependent individuals (Sekine et al., 2006) ...

5615: 1046: 927: 262:, half the sites you visit won't work unless you enable Google scripts on the page. We have no guarantee that one day they're not going to announce from on high that from now on you have to pay a subscription fee every month or else no searches, no scripts, no YouTube, no Yahoo, no maps, no translators. Knowledge is supposed to be an 4371:, I'll probably copy/paste the relevant citations from the body to the lead to address your citation concerns. The source contains comments after each lead paragraph that the relevant sources are attached to the corresponding sentence in the body (the lead is supposed to be a summary of the body). As for the specific issues you raised: 1389:

rapidly that Oberregierungsrat Linz of the Ministry of Health predicted in 1942 that more extreme measures would have to be taken against the drug, even though it had acceptable medical uses in treating vascular diseases. Such measures were never implemented, perhaps because the German police only knew of 84 pervitin addicts in 1942.

126:

that with an answer, and I shouldn't even have dignified this with a response. It's a ridiculous notion that you have introduced, and I suggest you do some more research to educate yourself. I wasn't trying to be rude, it's just offensive to the people who have contributed to the whole article, and that includes this section.

2045:

Nobody but you can ever know what you think doesn't fit - there's no way any reader is going to guess that pharmaceutical trademarks and production would go under the title you've come up with. I think at this point it may be best to go back and come up with a brand new idea for how to split it, if at all, based on

5534:

I, for one, agree with dream the wording is just bordering on inaccuracy and hence I can see his reason for editing it. Extensively, generally means that every part of the Axis powers would be using it, at least to some extent. But my agreement isn't strong enough for me to do anything about it, I'll

4229:

effects on male/female sex organs and libido (the explanation is rather technical); in a nutshell, men are far more likely to experience hypersexuality/hyperarousal symptoms than women. Unfortunately, that puts gay methamphetamine users at greater risk for pathological use than heterosexual or other

1812:

Because every section contains a lot of overlapping medical and recreational ("socio-cultural") components, components of several sections will need to either be removed or copied. I'm not certain about which sections to copy and which sections to remove when making the page split at this point; any

1388:

It must be clearly stated: the amendment did not constitute a ban; instead, a prescription was needed to obtain the drugs, and if the prescription was given for a long period of time, a record had to be sent to the proper authorities. In spite of the amendment, pervitin consumption ostensibly rose so

1291:

Possible cutting agents/substitute ingredients may include cyproterone acetate(Birth Control Pill) or the medroxyprogesterone acetate (MPA, the base ingredient in Depo Provera) for male impotence and hidden mobile phones for auditory hallucinations whhich can cause anxienty and as a result production

1014:

Note that "L-Methamphetamine" does not mean levorotary. It is using L/D notation. The L/D systems relies on the chemical correlation of the configuration of the chiral center to one of the sterospecific enantiomers. The compounds which can be correlated without inverting the chiral center are named

456:

This article is not vary informative in regards to Methamphetamine's use as a prescription drug for the treatment of ADHD. Almost all the information in the article is mostly relevant to abuse or use as a recreational drug. Should there be a second article or at least a section on medical use to make

4321:

Hi fellow Wikipedians, kudos to you all for tackling this topic! It seems to still have some problems, however. At least - here are my two cents for what its worth (if naything). First and foremost: treating the "meth" entry as just another pharmacological article squanders a HUGE opportunity for

4109:

I noticed that the only photos avalible here is the white legal pills. Should there not be a photo for each illegal form? what about adding a section dedicated to overcoming meth addiction and cravings? There is also no metion of the fact that Ice is 80 - 90% pure compared to Speed which is 50 - 60%

4049:

Ok, thanks. I missed the 5/10-year deadline. Better edit summaries in future, or simultaneous mention on Talk of planned deletions & rationale, would be quite helpful. On the subject of this material, is it not still of historical interest, as in, "As of 2002, it was though that (brief summary),

1719:

Carondelet St. Mary’s Hospital announced Friday that without a full-time medical director to oversee its burn unit, the hospital will have to close that portion of its Burn and Wound Care Program. ... She said the hospital initially looked at expanding the burn unit into a verified burn program with

1707:

The burn unit’s former medical director, Dr. Lesley Wong, left in February for family reasons. Her departure prompted hospital physicians and officials to reevaluate the capacity of the burn center and to acknowledge the unlikelihood of recruiting a new medical director to oversee a relatively small

1376:

However, according to Werner Pieper’s book, Nazis on Speed, the Nazis deliberately distributed the drug freely, intending to subdue the public and increase productivity. This claim has been cited and recited time and again, without a single shred of evidence. If such a grand conspiracy were true, an

419:

such as that parents can reduce drug use by using netnanny software and Erowid methamphetamine instructions are a threat to public health. I think that there could be some excellent social science done here, by someone willing to work - e.g. to track down a large number of people actually suffering

4835:

Neuroimaging studies have revealed that METH can indeed cause neurodegenerative changes in the brains of human addicts (Aron and Paulus, 2007; Chang et al., 2007). These abnormalities include persistent decreases in the levels of dopamine transporters (DAT) in the orbitofrontal cortex, dorsolateral

4341:

Lastly, I really don't want to embroil mysef in a highly technical edit of a highly viewed page. So, I hope my comments will be taken as helpful, rather than trollish. And, sorry for the typos -- I'm on my iPad, in bed, sick with th flu (and hopped to the gills on legal drugs, ironically!) (That's

4135:

I was planning on using the crystal shard image in recreational and an image of the free base (if I can find one) in chemical/physical properties. If you have a ref handy, I can add the purity info to the recreational section now. I'm still in the process of re-framing and adding relevant parts of

2835:

If you're not too busy at the time that I GA-nominate this article (sometime within the next 7 days), you'd probably be the ideal reviewer due to your familiarity with amphetamine and its layout. I don't plan or want to take this article to FA-class, so hopefully it won't be as much of a burden on

2287:

After thinking it over, I think breaking it down into sub-articles is a suitable idea if you want to do it that way. Go ahead and make the split if you're still interested; just be sure to use the copied template when you do. That said, what do you propose for the remaining content on amphetamine

1930:

The sections on the illicit production and distribution of the drug, including forensic analysis of impurities, belong in this main article because they are about the chemistry. The other article says rather explicitly the chemistry belongs here in the note at the beginning of it, and these things

1365:

X says: One of the earliest uses of methamphetamine was during World War II, when it was used by Axis and Allied forces. The company Temmler produced methamphetamine under the trademark Pervitin and so did the German and Finnish militaries. It was also dubbed "Pilot's chocolate" or "Pilot's salt".

1115:

REASON: The referenced article does not support the claim. Here is the relevant quote from the abstract: "At the temperature range examined, the higher ambient temperature did not significantly enhance METH-induced hyperthermia or METH-induced dopaminergic neurotoxicity, although there were trends

1111:

Please either remove the line "It has been demonstrated that a high ambient temperature increases the neurotoxic effects of methamphetamine." or change it to one of "It has been suggested that a high core temperature increases the neurotoxic effects of methamphetamine." or "It has been demonstrated

209:

see if we can use the leads we find in such ways to get to solid sources about how these things go wrong. Chemistry is not innately doomed to blow up; you just have to treat the would-be chemists with respect and foster an adult understanding of what they are contemplating, even if it doesn't seem

4842:

Structural magnetic resonance imaging (MRI) studies in METH addicts have revealed substantial morphological changes in their brains. These include loss of gray matter in the cingulate, limbic and paralimbic cortices, significant shrinkage of hippocampi, and hypertrophy of white matter (Thompson et

4325:

I wanted to gain a clearer picture of the different "types" of meth. ("Biker meth" versus "crystal" meth, which I gather are actually from different starting materals &/or methods of synthesis, so may be different chemicals entirely, but are nonetheless related culturally, and, thus should be

2190:

M Medical use M Effects M - 2.1 Physical M - 2.2 Psychological M - 2.3 Withdrawal M - 2.4 Long-term M - 2.5 Tolerance M 3 Adverse effects M - 3.1 Addiction M - 3.2 Psychosis M - 3.3 Meth mouth M - 3.4 Pregnancy and breastfeeding M - 3.5 Risk of sexually transmitted disease M 4 Pharmacology M - 4.1

2018:

I guess I should probably just explain what I had in mind when making the split. Both this and the amphetamine article are more or less structured like a combination of a chemical data sheet and medication guide for healthcare professionals - that's what I envisioned the two articles to look like

1780:

The current page has information on methamphetamine from a medical/chemistry standpoint, a historical perspective, and a socio-cultural standpoint, so I think moving some of the material to a page on the collective history and socio-cultural aspects of amphetamine and methamphetamine would help to

1372:

One of the earliest uses of methamphetamine was during World War II, when it was used by Axis and Allied forces. The company Temmler produced methamphetamine under the trademark Pervitin and so did the German and Finnish militaries. It was also dubbed "Pilot's chocolate" or "Pilot's salt". It was

1218:

The effects of 0.5 mg/kg are stronger for l-meth than d-meth, but at half that dose, l-meth shows no difference with placebo? And despite it's longer half-life, the effects dissipated more quickly.. This look more like a psychological phenomenon than anything else, perhaps associating the physical

1119:

The abstract does support a similar statement about core temperatures, but it is clear that causation has not been demonstrated: "Acute METH-induced increases in core temperature correlated highly and directly with subsequent decreases in striatal dopaminergic markers." and "These results suggest

379:

Oh, and as for "peer reviewed secondary sources", that's a standard that can't be met here, because we're not speaking of a scientific study but rather a sort of crime. It's not submitted for publication. We have to rely on sources like reporters and police and firefighters for their accounts of

5496:

It currently says "During World War II, methamphetamine was used extensively by the Axis forces for its stimulant effects." "The Axis forces" is nonspecific language; it's not saying just one, all, or a particular combination of the associated countries in that alliance. Feel free to specify it

5148:

I also wonder if any study has been done on toxic substances that unscrupulous drug dealers add to 'crystal meth' to stretch their inventories. One additive that I know of (methylsulfonylmethane) does not seem to bother 'snorters' or 'slammers', but causes 'smokers' to suffer headaches, abdominal

2306:

I'd likely leave the unwanted bits where they are until someone thinks of something for that end. I'm not going to rush to do this split right now - I'm amazed that an article like this that must have a high readership doesn't get more opinions on its talk page, but I should see if more comments

2109:

your title don't have anything to do with it - you have to recognize that's not going to work. (To illustrate that your move was not really that carefully looked over, no matter what projects weighed in on it, note that your new title doesn't even follow the standard rules for no-capitalization)

2108:

We don't normally do things in such a formal way - for one thing, the WikiProjects don't have any formal authority; they're just places to round up some editors. Certainly I can and have split articles in the past without looking for support in advance. But the sections you propose moving under

1485:

Ok. Which is it? Is it rarely prescribed as said in the lead or does everyone who gets a prescription (mostly people with narcolepsy, i'd imagine) going off and selling their pills? and that entire paragraph including the black box warning excerpt could stand to be rewritten or flat out deleted.

1207:

l-Methamphetamine, 0.5 mg/kg, was psychoactive, producing peak intoxication (46.0 +/- 35.3 versus 30.3 +/- 24.9) and drug liking (47.7 +/- 35.1 versus 28.6 +/- 24.8) ratings similar to 0.5 mg/kg d-methamphetamine, but the effects of l-methamphetamine dissipated more quickly (approximately 3 hours

233:

I do have some general concerns that if we're going to talk about synthesis, we should make an effort to link to authoritative external harm reduction-based guides, but I would prefer that we not talk about the precursors and synthesis process at all. I ask others to join me in keeping an eye on

125:

Maybe that's because most synthetic drugs are not made illicitly, even if they have a potential for abuse, you cannot illicitly produce most synthetic drugs yourself. This is a methamphetamine phenomenon, and what's laughable is that you think it's some sort of instruction manual? I can't dignify

5462:

What about Italy? There are three Axis powers. Was it "used extensively" for all three of them, or just extensively in Germany, and somewhat in Japan, and not in Italy at all? It says everyone used it for their pilots at times. Was Germany the only one who used it for ground soldiers though?

5345:

Its illegal to possess a drug like meth. It is not illegal to take a photo of said drug though provided it is not in one's possession and even then taking the photo would not be illegal. And besides while wikipedia likely has a moral duty to help enforce laws agaionst child sexual exploitation I

2044:

Honestly, I think that splitting the article was a bad idea in the first place, and splitting it according to "history, society, and culture" was a worse one. But using an article with a specified title as an unofficial grab bag for "everything that doesn't fit" absolutely isn't going to wash.

1954:

I agree that there's chemistry-related content in that section, but I'm kind of confused as to why you don't think that's entirely in the context of illicit methamphetamine culture. I'm not going to revert your edits, but instead just point out that if you really want that chemistry information

1795:

The content in several sections (Meth mouth, Public health issues, Risk of sexually transmitted disease, routes of administration, Natural occurrence, History, Illicit production, and Slang terms) are equally or more relevant to a socio-cultural context than the medical/chemistry context of this

1380:

During the Second World War, German military officials and the medical authorities debated the effectiveness of pervitin, especially for pilots. In the end, it was decided on October 25, 1941 that the drug should be put under lock and key. Official use continued in the military, but with extreme

360:

So far I've been looking at the section more as news than as science - the fact that there are a bazillion ways to make this simple compound is of some chemical interest, but mostly it becomes notable on account of the burns, explosions, environmental contamination, and the remarkably large and

1384:

Pervitin was not banned in Germany. In fact, the German drug law (known as the Opium Law of 1929) did not prohibit any type of drug, be it an amphetamine or another. Instead, drug use remained legal in Germany, but possession of drugs without a proper prescription was considered a misdemeanor.

5210:, but more or less the issue is whether or not the compounds are direct neurotoxins (usually analogous to saying that a substance is neurotoxic - these terms are loosely defined). All substances are indirectly neurotoxic at some (possibly extreme) dose or during unusual circumstances - e.g., 2073:

In that case, make your proposition, leave it open for a full week like I did, and propose it to WPMed and WPPharm like I did. I received a total of three message of positive feedback, 1 neutral, and 0 negative during the split discussion. IE this was a fully discussed, highly visible, 100%

1731:

So two burn units closed in 2008, for reasons that have nothing to do with meth patients or what AP calls "a crude new method of making methamphetamine". In summary: 2004-2007: 5 closures, 2007-2010: 3 closures, 2010-2012: one opening. Stating in 2012 that this new method is causing burn unit

4220:

I'd be quite happy to add more material, but I really don't have a decent secondary source on hand to document other groups of users. I expect more will be added in time if I don't come across any while I work on related articles (for comparison, there's literally nothing comparable to that

1511:

I honestly am done with this. This article is a lost cause right now. Really disappointing that this article can be protected and be so clearly vandalized and not immediately fixed. Maybe one day I'll torture myself and get those stupid 5 edits or whatever so I can fix shit like this...

5371:

It current says "During World War II, methamphetamine was used extensively by the Axis forces for its stimulant effects". The reference is a book about the Germans using it. I don't see any mention of it anywhere being used by the other Axis powers. Anyone got a reference for that?

4294:

Sorry for the delay in responding. I took a look at your edit to the article and it does seem to help clarify what is happening, while also taking a neutral line on the issue. As long as there are no other users who object to the section, I believe that the issue has been resolved.

5306:

I agree with Muchotreeo, having pictures provided they do not contain children engaged in sex acts, is perfectly legal, hence while the picture may cause government authorities to start enquiring into the personal life of the uploader it is of no concern to us as users of said image.

4072:

I'm not opposed to the idea, but it might be difficult for me to assess what the scientific consensus at some point in the past compared to the present. Even so, if there is a notable/interesting difference in consensus, I'll likely add it when I get to the history section. Regards,

1239:

Feel free to revert it back to the version saying levomethamphetamine is CNS inactive throughout the article without any citation, primary or otherwise. Although, personally, I don't think advocating the safety of a neurotoxin to midbrain dopamine neurons (i.e. meth) is a good idea.

479:

Given that it is a very rarely prescribed drug, I don't think it is justified to create a separate article. I do like your suggestion of creating a section for medical uses/therapeutic uses. A few sentences or paragraph in the lead/intro summarising therapeutic uses would be good as

4329:(1) NPOV violated by phrase, "Entirely opposite to the long-term use of amphetamine, ..." (This phrase is gratuitous; not necessary to the topic at had which is meth effects on brain, NOT differences between meth and other types of amphetamines.) Particularly as no citation given. 1720:

a full-time burn care medical director and specialized physicians. However, when recruitment failed, the next option was to close the program. Officials also cited a decreasing patient population – an average of two patients per day – as one of the factors leading to the closure.

5594:

pointed out, a lot of people are coming here to learn more about "street" meth. If the synthesis section of this article isn't going to cover the stereospecific reduction of l-ephedrine/d-pseudoephedrine to d-methamphetamine, it should at least provide a link to one that does.

848:

Desoxyn is known as methamphetamine hydrochloride; the chemical name is "(S)-N,α-dimethylbenzeneethanamine hydrochloride." This name may also be referred to as "metamfetamine" in the EU using International Non-Proprietary naming or "methylamphetamine" in the United Kingdom.

1990:

social consequences, rather than about the drug itself, but I think that tangible facts about the drug itself (not just the theoretical mode of synthesis, but how much in what form is made where) belong here. Put it this way: this article still needs a section detailing the

285:

Hmmm, looking at this again there's a chance I misunderstood you - "replacing" is one of those words with two equal and opposite meanings. Could you link an example of a "guide to reduce harm in production" so I get what you mean? (And more sources are always a good thing)

660:

EDIT: I know it mentions a few things, what I mean is that the recreational use section starts in the 1950s rather than covering recreational use beforehand. I know "shabu" was quite a hit in Japan even in the 1920s at least within some social circles. Why no mention of

5001:

Hart H, Radua J, Nakao T, Mataix-Cols D, Rubia K (February 2013). "Meta-analysis of functional magnetic resonance imaging studies of inhibition and attention in attention-deficit/hyperactivity disorder: exploring task-specific, stimulant medication, and age effects".

2191:

Pharmacokinetics M - - 4.1.1 Detection in biological fluids A - 2.2 Military use A - 2.3 Medical and legal over-the-counter sales A 6 Recreational use A - 6.1 Routes of administration A - 6.1.1 Injection A - 6.1.2 Smoking A - 6.1.3 Insufflation A - 6.1.4 Suppository

4527:

In contrast to the adverse neuroplastic effects evident in methamphetamine addicts and abusers, long-term use of amphetamine or methylphenidate at therapeutic doses appears to produce beneficial changes in brain function and structure, such as normalization of the

1409:

That's far too long for this article, and it is also completely lacking in source information that could be used to verify the statements. I have no idea why you call this a "racial pejorative" -- I'm of German ancestry myself, and I see nothing offensive in it.

1985:

is also "culture". Everything is kind of society or culture, because it happens in the context of society or culture. So that's not really a workable distinction. I think that bits like the closing of burn wards can be transferred to society because they're

380:

what they're run into, because nobody shows up at a meth-maker's doorstep says he's from the local university and he's taking a representative statistical survey of manufacturers and he'd like to start by asking whether the synthesis uses mercury chloride...

3904:

by default). I didn't state this in my edit summary, but the following uncited sentence was entirely wrong (and non-sequitur due to use of "neurotransmitter" in place of "dopamine"), since meth's neurotoxicity in human dopamine neurons involves transporters

895:

The citation is a link to the abstract information but not the full journal article. I included a link to the full PDF file only so you can verify the contents and see that the information cited is mis-cited and the reference supports my change request.

4338:(4) If you can find it online, the book Methland makes repeated mention of a groundbreaking series of articles on the spread and scourge of meth that appeared in the newspaper, The Oregonian, by journalist Steve Sou, "An Unnecessary Epidemic," Oct. 2004. 1689:

Associated Press interviews and an examination of official figures found that the shrinking number of beds is a growing cause for concern in this post-Sept. 11, 2001, world. The number of burn centers in the United States has dropped from 132 in 2004 to

1507:

I propose that "Uses" section be totally reserved for "Medical Usage" and the title changed accordingly. Recreational use section is completely redundant as is the "Effects" section. All of that information repeats itself below under "Adverse effects."

5137: 1219:

effects with methamphetamine use, and anticipating the desired effects, which never came. I guess the authors themselves realized that, seeing as they use the term "psychodynamic effect", for which google only returns psychotherapy related links.

1995:

synthesis of Desoxyn in the same way, describing the synthesis route used, what companies make it, how much they make and how many people it is prescribed to, etc. Would you put all that in the article about "society, history, and culture"?

5188:

show that data on the neurotoxicity of amphetamine is inconclusive and needs to be studied more, while it is listed as fact that amphetamine and cocaine are not neurotoxic. (I found an abstract on cocaine neurotoxicity but I lost it)

2265:

Sorry, I meant to strike those items out. Done now. Also the reason why I keep saying it's the wrong title isn't even because of the amphetamine/methamphetamine part, rather the second part seems to rule out chemistry and industry.

179:

to cover this is if we use the opportunity and do our job of getting comprehensive information to those who request it, namely, explaining to the would-be soda pop bottle rebels exactly how their procedure can turn into a nightmare.

552:

The first paragraph says "Methamphetamine , japaneses and germany make this medicine of bad killing people , in oosaka japan methamphetamine making city do kill japaneses self from 1883 1888 1943 1945 1947 1952 2012 with making 731

257:

excuse. The point of Knowledge is to make information free, not under the copyright of some private corporation. If you haven't noticed, Google keeps buying up vastly important Internet companies one after another. If you run

4904:

Itzhak Y, Martin JL, Ali SF (October 2002). "Methamphetamine-induced dopaminergic neurotoxicity in mice: long-lasting sensitization to the locomotor stimulation and desensitization to the rewarding effects of methamphetamine".

1471:

the frequency in which this drug is prescribed isn't particularly relevant and this sentence is what made me curious to finish reading. the entire article seems to be written by someone who has a very clear anti meth agenda.

277:

The other issue is that a desperate meth head may be satisfied with the first hit that gives him a simple recipe, without bothering to look on for other pages that might talk about safety issues. Let's make his first hit a

4855:

Yuan J, Hatzidimitriou G, Suthar P, Mueller M, McCann U, Ricaurte G (March 2006). "Relationship between temperature, dopaminergic neurotoxicity, and plasma drug concentrations in methamphetamine-treated squirrel monkeys".

2175:

the article is split, it should be into three branches. I'm thinking the breakdown would be roughly as follows - though some sections, especially those for history, would need to be split up almost sentence by sentence.

1683:"At least seven burn units across the nation have shut down over the past six years, partly due to consolidation but also because of the cost of treating uninsured patients, many of whom are connected to methamphetamine." 995:

REASONING: This is unsubstantiated. The source referenced does not state that levomethamphetamine is an OTC nasal decongestant. The source does not contain the word "levomethamphetamine" nor "nasal" nor "decongestant."

1785:(this will need to be renamed after the split to incorporate the material on meth) and reduce the excessive size of the current article. I'm proposing this for the following policy and article-quality related reasons: 609:

It looks to me as if the benzene ring contains the correct alternating double- and single-bonds. Perhaps the "shininess" of the bonds is making it look to you as if there is a triple bond that is not really there? --

1481:

Because methamphetamine is highly abused for negative purposes such as selling the prescription to others, or overdosing (which c ontributes to very dangerous side effects) than using the medication medically ... "

845:

REASON FOR CHANGE, ADDITIONAL INFORMATION AND SOURCES: The referenced article does not make any mention to "dextromethamphetamine." I believe this is a typo/oversight. (PDF link to Journal article found below.)

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The final product shown in the synthetic route to methamphetamine by the thionyl chloride route is labelled incorrectly - it is methamphetamine, not amphetamine; amphetamine has no methyl group off the nitrogen.

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M 5 Illicit production of methamphetamine M - 5.1 Synthesis M - 5.2 Production and distribution M - 5.3 Impurities and adulterants A - 2.1 Discovery (Missing) Legal production and distribution of methamphetamine

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There is compelling evidence that the negative neuropsychiatric consequences of METH abuse are due, at least in part, to drug-induced neuropathological changes in the brains of these METH-exposed individuals ...

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I actually wasn't aware that I was "replacing" anything; I'll have to look over the history to see if there are goodies there I can work with. The only recent removal I noticed before was a small unsourced bit.

4205:

Just a question, but does the Recreational section need to focus on only one source talking specifically about people who are gay who use it? I at least feel it could be a violation of NPoV due to the focus.

1983:"Methamphetamine is sold under the name Desoxyn, trademarked by the Danish pharmaceutical company Lundbeck. As of January 2013, the Desoxyn trademark had been sold to Italian pharmaceutical company Recordati." 1800:

also provides guidance on dividing the article into its medical/chemistry component and the aforementioned components, which have a content/context (socio-cultural and historical) overlap with the material in

1022:. You can search and find "cough/cold" under Monograph and "nasal decongestant" under Sub-category. This FDA list of OTC medications in the United States contains two entries for "levmetamfetamine" . 4335:(3) To have "meth" diambiguate to here is a huge disservice, as there is almost no cultural info. on "meth" here. It's all chemistry, which even makes MY eyes glaze over, even WITH my minor in chemstry! 502:

That article did exist at one point, but has since been deleted or merged. This article has had a medical use section for years and it's hardly changed so if you have something to add to it, please do.

144:

I'm sorry you are upset and offended, but yes, I do think the synthesis descriptions act as a basic instruction manual. Would you object to rewording the section in less procedural terms, on principle?

2897: 1935:"history", "society", or "culture", but scientific in nature. Therefore I've brought them back. I've also moved a little section on present legality to that article, because it doesn't make sense ( 679:"while levomethamphetamine is a non-prescription over-the-counter nasal decongestant." Please specify what countries you are talking about, or else I beleive this is referring to pseudoephedrine. 2030:

Also, now that you point it out, that information should probably go on the other page as well. I'll need to make another small split in the future to gather things I missed from the first split.

5149:

discomfort, and other symptoms of acute poisoning. Possibly heating the mixture to over 300 degrees Celsius while subjecting it to a blast of air in the 'meth pipe' creates a more toxic product.

1478:,... the therapeutic/recreational effects of this drug is not called amphetamine psychosis. I'm not a medical profession but amphetamine psychosis is caused by staying up for 4+ days while high 2243:

Just to make sure I understand, you're proposing to put amphetamine content under a methamphetamine title (Methamphetamine and Society), after raising the issue an hour ago that the (formerly)

624:

Oooh... you are right. I guess there are only 2 bonds, but the reflections (which are less pronounced on the other two double bonds in the ring) made it look different. No problems here, then.

3917:

synthesis: "Short-term tolerance typically lasts until neurotransmitter levels are fully replenished; because of the toxic effects on dopaminergic neurons, this can be greater than 2–3 days."

843:

TO: "Although rarely prescribed, methamphetamine hydrochloride is approved by the U.S. Food and Drug Administration (FDA) for the treatment of ADHD and obesity under the trade name Desoxyn."

195:(incidentally, I would not recommend joining in that conversation, as some of the questions seem phrased so as to support a conspiracy charge). There are little nuggets of joy in there like 2808:

and subsequently GA-nominate this article upon completion. If anyone has an objection to any of my changes, I'd ask that you bring up your concerns here instead of immediately reverting.

1292:

of adrenaline by user. The lack of stimulant properties may also induce anger in the user and therefor also assisting the production of adrenaline by user. Fear and Loathing, Lol...

1193:

The reference for stereotypy and psychosis is a study of rats with stereotaxically implanted guide cannulae in their skull. Makes me wonder how one would recognize psychosis in rats...

841:

FROM: "Although rarely prescribed, dextromethamphetamine is approved by the U.S. Food and Drug Administration (FDA) for the treatment of ADHD and obesity under the trade name Desoxyn"

1808:

I don't see this article achieving a higher rating from the chemicals/medicine/pharmacology wikiprojects without some action being taken to address the size and scope of the article.

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neurons. It has been demonstrated that a high core temperature is correlated with an increase in the neurotoxic effects of methamphetamine. As a result of methamphetamine-induced

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that the whatever deficiencies you find in the image outweigh its value to the article. The way to do that is most certainly not to namecall. Incidentally, the image is hosted on

2218:

A 4 Society and culture (methamphetamine) A - 4.1 Risk of sexually transmitted disease A - 4.2 Ambulance attendances A - 4.3 Illegal laboratories A - 4.4 Burns A 5 Slang terms

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It mentions nothing about its use in Japan or the rest of the world in its earlier years before it became illegal. Why does the history in this article start in the 1950s?

3432:

Santagati NA, Ferrara G, Marrazzo A, Ronsisvalle G (2002). "Simultaneous determination of amphetamine and one of its metabolites by HPLC with electrochemical detection".

1430:

The current mol wt is 149.2337 - I think the value should be 149.237 carried to three places based on the atomic weights for C, H and N in wikipedia for formula C10H15N

2522:

Kuczenski, R (1995 Feb). "Hippocampus norepinephrine, caudate dopamine and serotonin, and behavioral responses to the stereoisomers of amphetamine and methamphetamine".

2221:

Each branch should have a more specific article, and each specific article should be summarized in the main article. The idea is that all aspects of the drug should be

1002:

If the author is trying to reference the levorotary enantiomer for "methamphetamine," simply adding the prefix "levo" is not the proper use of chemical nomenclature.

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Davidson C, Gow AJ, Lee TH, Ellinwood EH (August 2001). "Methamphetamine neurotoxicity: necrotic and apoptotic mechanisms and relevance to human abuse and treatment".

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At high doses, l-methamphetamine intoxication is similar to that of d-methamphetamine, but the psychodynamic effects are shorter-lived and less desired by abusers.

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seen on PubMedCentral. Their experiment involved running a total of nine Google searches, looking at the first 20 hits, and concluding from them a long list of

2135:

in such cases. This is a contentious enough move to require discussion simply because I disagree with you. Moreover, you should probably take the time to read

1586:

ya some asshole fucktard added something completely off topic and unrelated. its a disgusting photo. i simply just want to take it off and block the uploader.

1501:

Moreover, methamphetamine use is associated with an increased risk of Parkinson's disease due to the fact that uncontrolled dopamine effluxion is neurotoxic. "

121:

I'm sorry, but that is just laugh out loud funny. There is an illicit production section because there is an illicit production epidemic with methamphetamine.

5052:"Effect of psychostimulants on brain structure and function in ADHD: a qualitative literature review of magnetic resonance imaging-based neuroimaging studies" 2051:

classifications. By monophyletic, I mean, any sub-articles are about one particular topic and branches of that topic. So we could end up with articles like

1361:

Please change X to Y because X (the current Wiki entry) is a racial pejorative against Germans & improperly uses sensationalized magazines as citations!

1634: 175:. This makes the shake-and-bake method notable and appropriate for Knowledge to cover. The current version is indeed woefully incomplete. What makes it 1010:

Also known as: L-Methamphetamine, l-Methylamphetamine, (-)-Methamphetamine, Vicks Inhaler, d-Methamphetamine, (-)-Deoxyephedrine, R(-)-N-Methylamphetamine

4495:. Moreover, there are adverse changes in various metabolic markers of metabolic integrity or synthesis in methamphetamine abusers, such as reductions in 2244: 2083: 1802: 1782: 4456:

Although all of the mechanisms are not fully understood, methamphetamine is a known neurotoxin in both lab animals and humans. Beyond neurotoxicity,

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Thanks for taking the time to respond, Seppi. I shall hold off on my comments (if any) till later, since clearly these pages are in flux. Cheers!

3896:

This isn't really relevant now that I'm done editing that section. In any event, both sources were way out of date for a medical secondary source (

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like a how-to manual - it's not a call for censorship but a matter of style. We don't say "first add this, then this, shake, wait 15 minutes". We

1671:

this method of synthesis has been blamed for the closure of hospital burn units and a cost to taxpayers of tens or hundreds of millions of dollars.

274:

with private search engines which, to me, seem largely overlapping in function, by doing so we help reduce the chance such a scenario will develop.

3618:"Recommended methods of the identification and analysis of amphetamine, methamphetamine, and their ring-substituted analogues in seized materials" 234:

this, and if consensus develops for replacing precursor information or including detailed synthesis information (which I still believe is against

1123:

So the present wording is simply not supported. It should be eliminated or replaced with one of the weaker conclusions about core temperatures.

2441:

Melega, WP (1999 Feb). "l-methamphetamine pharmacokinetics and pharmacodynamics for assessment of in vivo deprenyl-derived l-methamphetamine".

2123:

Given that methamphetamine is a highly visible article and content moves are likely to be contentious, I did it the formal way as suggested in

420:

severe burns from these attempts and figuring out what methods and specific reagents they used and seeing if they can explain what went wrong.

4424:, a mechanism of neurotoxicity. Similar to the neurotoxic effects on the dopamine system, methamphetamine can also result in neurotoxicity to 2139:(as well as archived discussion in WPMED) before you make more assertions about the lack of oversight. I did find the comment amusing though. 4611: 3970: 1465:

This article is a disaster. I've read it before at least a year ago but wow... Did it get vandalized and people were too lazy to revert it?

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How legal is it to have that image of a person holding meth as in the Recreational Use section? It must mean possession because how else?

4264:

Ha, ok... I just realized why it might seem homophobic on the face of it without additional knowledge of that sub-culture - let me know if

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I'm swamped with school work at the moment, but this article could really use a brief discussion of the purported epidemic in North Korea:

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The study linked is from 1994 and is not relevant to this claim. I'm certain this sentence is correct but a better cite is needed imo

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A 3 Society and culture (amphetamine) A - 3.1 In literature A - 3.2 In music A - 3.3 In film A - 3.4 In mathematics A - 3.5 Smuggling

172: 5276: 4380:) differences between amphetamine and methamphetamine. The relevant passages from the body, with citations, are included in item 2. 882:

methylphenidate - Ritalin, Ritalin SR, Ritalin LA, Concerta, Daytrana, Metadate, Metadate CD, Metadate ER, Methylin, Quillivant XR

171:

explain the process conceptually. I've looked up this article just now because I saw perhaps the same AP article you did, namely

3986:

Bennett BA, Hollingsworth CK, Martin RS, Harp JJ (1998). "Methamphetamine-induced alterations in dopamine transporter function".

3562:

Eiden LE, Weihe E (2011). "VMAT2: a dynamic regulator of brain monoaminergic neuronal function interacting with drugs of abuse".

2779:

I strongly disagree, Seppi333. Why do you think this? The lack of emntion of North Korea in this article is, IMO, systemic bias♫

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I doubt two animal studies (one about deprenyl, not amphetamine) and one study with 12 addicts, all three primary sources, meet

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ball-and-stick model of the chemical, why is there a triple carbon-carbon bond in the ring? Shouldn't it only be a double bond?

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Neuropsychological studies have detected deficits in attention, working memory, and decision-making in chronic METH addicts ...

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I agree that the wording was not supported by the cited references. I have altered the wording according to your suggestion.

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appears to be on-topic and very much related to the subject of the article. "Disgusting" is in the eye of the beholder, and

1202:

The elimination half-lives were longer for l-methamphetamine (13.3-15.0 hours) than for d-methamphetamine (10.2-10.7 hours).

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Subsequent comments should be made on the appropriate discussion page. No further edits should be made to this discussion.

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The conclusions regarding psychostimulant effects in humans come from a trial involving twelve methamphetamine "abusers":

4332:(2) NO CITATIONS indicated for any of the first three paragraphs! MUST be fixed, as very specific assertions are made. 1963:

content relevant to illicit drug culture than synthesis information, so I personally think it belongs on the other page.

102:

Why does this article have an "Illicit production" section? Is there any good reason this article gets an exemption from

5219: 4464:

changes, such as significant abnormalities in various brain structures. In particular, methamphetamine appears to cause

3877:

was improperly reasoned: edit summary claimed failure of MEDRS, which is false on its face. Both sources have excellent

4234:

BT meth users. In the event you want to see it, there's several copies of the complete documentary on youtube, e.g.,

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Perhaps the author intended to write "levmetamfetamine" is a non-prescription over-the-counter nasal decongestant.."

303:

says, "Erowid was the only website in this sample to contain detailed information on methamphetamine synthesis," but

2804:

Over the course of this week, I'm going to rewrite and resource this article to mirror the layout and formatting of

992:

REMOVE THE FOLLOWING LINE: ", while levomethamphetamine is a non-prescription over-the-counter nasal decongestant."

4457: 38: 3900:- 5 year limit for areas of active research. 10 years is pushing it.) Half of each paragraph was uncited (Fails 1792:

suggests cutting an article when the size reaches 100k. As of writing this talkpage entry, the article is at 113k.

238:) that we link to guides specifically designed to reduce harm in production and use. They are not hard to google. 5548: 5320: 2385: 2211: 1517: 1033: 914: 906: 839:

Please change "dextromethamphetamine" to "methamphetamine hydrochloride" as found in the FROM/TO sections below.

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For the same argument on the amphetamine page (copy/pasting what I wrote from that talk page, with some edits):

270:

source of information, not under anybody's lock and key. And by keeping it free, keeping it useful, keeping it

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Miyazaki I, Asanuma M (June 2008). "Dopaminergic neuron-specific oxidative stress caused by dopamine itself".

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by triggering a cascading release of dopamine in the brain characterized as Amphetamine/Stimulant psychosis.

338:

Do you mean to do that? Would you agree to requiring peer reviewed secondary sources for this sort of thing?

5346:

think it would be highly controversial to argue that wikipedia has a duty to enforce drug prohibition laws♫

5050:

Spencer TJ, Brown A, Seidman LJ, Valera EM, Makris N, Lomedico A, Faraone SV, Biederman J (September 2013).

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During World War II, methamphetamine was used extensively by the Axis forces for its stimulant effects????

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Desoxyn may be prescribed off-label for the treatment of narcolepsy and treatment-resistant depression. "

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bupropion - Wellbutrin, Zyban, Budeprion SR, Aplenzin, Buproban, Wellbutrin SR, Wellbutrin XL, Forfivo XL

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feedback would really be appreciated, as this split isn't going to be as clear-cut as recent one on the

1737: 1678: 1399: 1230: 1189:, but levomethamphetamine is less desired by drug abusers because of its weaker pharmacodynamic profile. 1186: 441: 2730:

http://www.washingtonpost.com/blogs/worldviews/wp/2013/08/21/how-north-korea-got-itself-hooked-on-meth/

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use). In any event, the coverage of meth use in the gay population is mainly due to meth's differing

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I've given the source a close reading and the text now reflects what the paper actually says. Thanks.

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http://www.redorbit.com/news/health/1470803/chattanooga_erlanger_officials_explain_burn_unit_closure/

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http://www.cbsnews.com/8301-501367_162-57363650/ap-impact-meth-fills-hospitals-with-burn-patients/

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Cruickshank CC, Dyer KR (July 2009). "A review of the clinical pharmacology of methamphetamine".

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In the event you have time, I'll probably need your expertise with the synthesis section again.

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Unlike cocaine and amphetamine, methamphetamine is directly toxic to midbrain dopamine neurons.

2329:

I accidentally removed the info box from here instead of the article I thought I was starting.

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to dopamine neurons. Moreover, methamphetamine abuse is associated with an increased risk of

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versus 6 hours). The effects of 0.25 mg/kg l-methamphetamine were similar to those of placebo.

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lol. as if this section is needed when the entire article is devoted to demonizing this drug

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Methamphetamine is used as a recreational drug for its euphoric and stimulant properties. "

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that a high core temperature is correlated with the neurotoxic effects of methamphetamine."

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site. Nor is it a reliable source, having apparently been composed from monograph e-mails.

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Sulzer D, Zecca L (February 2000). "Intraneuronal dopamine-quinone synthesis: a review".

300:

I may be mistaken. I've seen some over the past year which look to have been taken down.

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http://tucsoncitizen.com/morgue/2008/08/23/94600-st-mary-s-closing-burn-unit-on-sept-1/

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I can't even understand that -- but I'm sure that if I did, the answer would be "no".

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that, as in rodents, core temperature can influence METH neurotoxicity in primates."

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It could be a DEA image, but it doesn't matter because have pictures isn't illegal.

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but research in the 2010s showed that (case) was a more accurate model." ? Best, --

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Mendelson, J (2006 Oct). "Human pharmacology of the methamphetamine stereoisomers".

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Besides some minor issues, I'm more or less finished with editing. How's it look?

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In 2010, there were 124 burn units, in 2012 there were 125 (ABA NBR Annual report).

1015:

D (capital D), those correlated to its enantiomer are designated as L (capital L).

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The Journal of neuroscience : the official journal of the Society for Neuroscience

2214:

A - 2.4 Recreational use and prohibitive regulations A - 2.5 Present legal status

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i have intimate experience -- gave it up when the old stuff was gone .......ck

2696:

old way--50 miles from anywhere -- it stank new way--the motel room next to you

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If you wish to start a new discussion or revive an old one, please do so on the

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page. Tentatively, my thoughts on what to do with these sections is as follows:

1025:

Please remove the end of the statement as requested above, as it is incorrect.

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http://www.vicks.com/products/vapo-family/vapoinhaler-nasal-congestion-relief/

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which persist beyond the withdrawal period for months, and even up to a year.

436:

I agree with Selery. The instruction section does not belong in the article.

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Source given is About.com which in turn gives this 2012 AP story as source:

205:

Now of course we can't cite a bunch of meth heads gabbing on a forum but we

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Thrash B, Thiruchelvan K, Ahuja M, Suppiramaniam V, Dhanasekaran M (2009).

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Malenka RC, Nestler EJ, Hyman SE (2009). "15". In Sydor A, Brown RY (ed.).

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clonidine - Catapres, Catapres-TTS, Duraclon, Jenloga, Kapvay, Nexiclon XR

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deletion of unsourced statements pertaining to ingredients and precursors

211: 187: 4683:"Methamphetamine-induced neurotoxicity: the road to Parkinson's disease" 1939:) to separate the modern-day legality from the historical legal status. 1649:, an affiliated site over whose content Knowledge exercises no control. 4741: 4507: 4436: 3840:

I added an abbreviated list of these in note 1 (note in 1st sentence).

2430:

http://www.fda.gov/downloads/AboutFDA/CentersOffices/CDER/UCM135691.pdf

1020:

http://www.fda.gov/downloads/AboutFDA/CentersOffices/CDER/UCM135691.pdf

4460:

studies on human methamphetamine addicts and abusers indicate adverse

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http://www.sagepub.com/weisiacapstudy/articles/Chapter08_Article03.pdf

1679:

http://www.nbcnews.com/id/46104151/ns/health-addictions/#.Uixi19e-6CF

3801:-- My question would be- how to keep this list reliably referenced. 457:

the article as informative as other pages on pharmaceutical drugs?

4605:

Molecular Neuropharmacology: A Foundation for Clinical Neuroscience

1902:. Seems like a good idea to me. The article is indeed overly long. 5206:

Sorry for the late reply! This issue is actually in discussion at

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http://www.unodc.org/unodc/en/frontpage/tik-meth-in-cape-town.html

336:

replacing informal synthesis instructions sourced to news stories.

2938:

Supplemental Amphetamine pharmacodynamics for comparison section

2225:

in the main article, rather than delegating some and not others.

230:

and no longer have any concerns with the section in particular.

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Progress in Neuro-psychopharmacology & Biological Psychiatry

2419:

http://en.wikipedia.org/Chirality_(chemistry)#Naming_conventions

3787:

There should be a list of slang and other names for Meth added

2898:

File:Methamphetamine from ephedrine via chloroephedrine en.png

2397:

http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=841240

2132: 1769:

The discussion concluded with a consensus to merge the content

1534: 1328: 1258: 1078: 959: 806: 106:? Most articles on synthetic drugs don't have such a section. 25: 1018:

Here is a comprehensive list of OTC drugs listed by the FDA:

741:

Well here's some citation for any diligent editor to put in:

123:"Most articles on synthetic drugs don't have such a section." 4342:

why I'm in the Talk pages and not doing actual edits! lol)

2733:

http://www.cnn.com/2013/08/30/world/asia/north-korea-drugs/

2699:

there is a big difference it may be the dextro vs levro

2375:

http://www.fda.gov/downloads/Drugs/DrugSafety/ucm088582.pdf

2207:

Laws, social reactions, and consequences of methamphetamine

2094:; i.e. none of those are sub-articles of one of the others. 4521:

Methamphetamine#Comparison to amphetamine pharmacodynamics

2941:

Amphetamine psychosis section w/ Cochrane ref (See source)

1981:

Well, you could say the same thing about a paragraph like

1173:

Dextromethamphetamine is a stronger psychostimulant, but

4858:

The Journal of Pharmacology and Experimental Therapeutics

2443:

The Journal of pharmacology and experimental therapeutics

2082:) 17:53, 27 September 2013 (UTC) I should also add that 1149:

http://elkhorn.unl.edu/epublic/live/g1748/build/g1748.pdf

5220:

catastrophic brain damage from a water/salt interaction

4265: 4175: 4171: 3875: 2247:

title didn't fit well with content on methamphetamine?

701:

Minor Correction in "Thionyl chloride synthesis" scheme

335: 227: 2920:

Drugbank Methamphetamine (Toxicity excerpt censored)

2074:

consensus split - so you seem to be alone on that one.

899:

Here is a pdf file to the Desoxyn medication guide: .

5434:

page 3 discusses Japanese use during the war briefly,

858:

amphetamine/dextroamphetamine - Adderall XR, Adderall

192:

Now there are indeed how-to sites out there, such as

1762:

Subsequent comments should be made in a new section.

4642: 4640: 3963:

Drugs and Addictive Behaviour: A Guide to Treatment

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Methamphetamine as a chemical or industrial product

642:

What About Really Early History of Methamphetamine?

4799:"Methamphetamine toxicity and messengers of death" 4607:(2nd ed.). New York: McGraw-Hill Medical. p. 370. 4110:pure. Thorghts on adding these ideas and photos? ( 2872:File:Methamphetamine from ephedrine with HI en.png 1699:Two units that closed between 2007 and 2012 were: 1687:Five years earlier, in 2007, we had this report: " 1005:Levmetamfetamine - Substance Summary (SID 841240): 5442: 870:dextroamphetamine - Dexedrine, Liquadd, ProCentra 5497:though - I don't really care how it's written. 5449: 2137:Talk: Amphetamine: History, Society, and Culture 2059:. Again, I'm not sure about even those splits. 1609:I don't see anything. Can you be more specific? 909:) 01:34, 3 February 2013 (UTC)ChemistryWikiWiki 5575:Under synthesis, there should be a link to the 5440:discusses its use by several major combatants. 4792: 4790: 4788: 4786: 4784: 3818:History and culture of amphetamines#Slang terms 3745:. National Center for Biotechnology Information 3393:. National Center for Biotechnology Information 3297:. National Center for Biotechnology Information 3251:. National Center for Biotechnology Information 3205:. National Center for Biotechnology Information 2866:Possible images to use in the synthesis section 1955:devoid of a cultural context on this page, use 851:ADHD medications in the United States include: 523:Archived all talk from 2009-2011 to Archive 4. 5128:Note to self: link to the relevant section on 893:Here is a pdf file to the inline citation : . 676:I beleive there is an error in the text here: 1765:A summary of the conclusions reached follows. 8: 5096:: CS1 maint: multiple names: authors list ( 5035:: CS1 maint: multiple names: authors list ( 4986:: CS1 maint: multiple names: authors list ( 4938:: CS1 maint: multiple names: authors list ( 4889:: CS1 maint: multiple names: authors list ( 4713:: CS1 maint: multiple names: authors list ( 4629:: CS1 maint: multiple names: authors list ( 1705:Chattanooga, Tenn. Erlanger hospital 2008: 186:? It looks like someone shaving meat for a 163:That policy says that an article should not 2836:you if you decide to take on the GA-review. 2057:Methamphetamine production and distribution 5587:. I'd do it myself but my account is new. 4598: 4596: 4387: 3344:United States Food and Drug Administration 2972:United States Food and Drug Administration 2245:Amphetamine: History, Society, and Culture 2084:Amphetamine: History, Society, and Culture 1803:Amphetamine: History, Society, and Culture 1783:Amphetamine: History, Society, and Culture 1575:The following discussion has been closed. 1566: 5535:leave it to him/her to fix this problem. 5074: 4821: 4551:, but I'll look into it for that article. 4033:CS1 maint: multiple names: authors list ( 3518: 3479:CS1 maint: multiple names: authors list ( 2926:Metabolite citations for the amph pathway 2798:Major rewrite + content re-split underway 2682:http://www.jonathanlewy.com/tag/pervitin/ 1665:Burn unit closures due to "Shake 'n Bake" 452:Seperate page for Desoxyn or medical use? 5179:Neurotoxicity of amphetamine and cocaine 3913:) as opposed to the enzymes involved in 3699:. University of Alberta. 8 February 2013 3653:. University of Alberta. 8 February 2013 3625:United Nations Office on Drugs and Crime 3159:. University of Alberta. 8 February 2013 3113:. University of Alberta. 8 February 2013 3067:. University of Alberta. 8 February 2013 3021:. University of Alberta. 8 February 2013 1147:Reference 88 seems to be a dead link to 4592: 4420:due to excessive pre-synaptic dopamine 4390: 3952: 2956: 2408:http://en.wikipedia.org/Stereoisomerism 2356: 5089: 5028: 4979: 4955:Brain Research. Brain Research Reviews 4931: 4882: 4706: 4622: 4221:documentary available on recreational 4105:Photos and Other ideas for new section 4023: 4012: 3966:. Cambridge University Press. p. 114. 3766: 3756: 3720: 3710: 3674: 3664: 3599: 3588: 3544: 3533: 3469: 3458: 3414: 3404: 3368: 3357: 3318: 3308: 3272: 3262: 3226: 3216: 3180: 3170: 3134: 3124: 3088: 3078: 3042: 3032: 2996: 2985: 2663: 2659: 2647: 2635: 2631: 2621: 2605:Clinical pharmacology and therapeutics 2582: 2578: 2566: 2554: 2550: 2540: 2501: 2497: 2485: 2473: 2469: 2459: 2344:Dummy section for reflist talk closure 2188:Methamphetamine use and health effects 1883:Comments would be greatly appreciated! 738:Sentence one: "also known as... tik " 44:Do not edit the contents of this page. 3337:"Adderall XR Prescribing Information" 2027:, which are virtually the same topic. 1959:. That material definitely contains 1717:Carondelet St. Mary’s Hospital 2008: 548:Someone vandalized the 1st paragraph. 7: 5401:I don't see what the issue is here. 4547:(4) That's probably more suited for 4136:the split content though. Regards, 2885:File:Methamphetamine from P2P en.png 2820: 2200:Methamphetamine production and trade 2129:Knowledge:Merging#Proposing a merger 1847:Risk of sexually transmitted disease 1796:article. Because of this,, I think 1756:The following discussion is closed. 1708:unit, Erlanger CEO Jim Brexler said. 5581:History and culture of amphetamines 5130:history and culture of amphetamines 4549:History and culture of amphetamines 2912:Pre-formatted sources for inclusion 2751:History and culture of amphetamines 1732:closures seems a bit of a stretch. 253:"They are not hard to Google" is a 4797:Krasnova IN, Cadet JL (May 2009). 568:Who gives a shit? Just revert it. 24: 4815:10.1016/j.brainresrev.2009.03.002 2965:"Desoxyn Prescribing Information" 1957:Substituted_amphetamine#Synthesis 1169:Regarding the following claims: 5613: 4661:10.1111/j.1360-0443.2009.02564.x 4450:Methamphetamine#Pharmacodynamics 3627:. United Nations. 2006. pp. 9–12 3576:10.1111/j.1749-6632.2010.05906.x 3512:10.1111/j.1471-4159.2010.07109.x 2821: 2749:It's probably more suitable for 1917:The discussion above is closed. 1625: 1538: 1332: 1262: 1082: 1044: 963: 925: 885:nortriptyline - Pamelor, Aventyl 810: 29: 5016:10.1001/jamapsychiatry.2013.277 4439:, chronic use may also lead to 4118:) 12:43, 2 January 2014 (UTC)) 956:Edit request on 3 February 2013 803:Edit request on 3 February 2013 4412:, methamphetamine is directly 2348:22:58, 31 December 2013 (UTC) 2317:20:20, 30 September 2013 (UTC) 2298:20:54, 29 September 2013 (UTC) 2276:00:37, 28 September 2013 (UTC) 2257:00:19, 28 September 2013 (UTC) 2235:23:12, 27 September 2013 (UTC) 2149:23:22, 27 September 2013 (UTC) 2119:22:36, 27 September 2013 (UTC) 2104:17:57, 27 September 2013 (UTC) 2069:16:45, 27 September 2013 (UTC) 2040:16:12, 27 September 2013 (UTC) 2006:02:49, 27 September 2013 (UTC) 1973:19:14, 26 September 2013 (UTC) 1949:07:37, 26 September 2013 (UTC) 1912:01:35, 23 September 2013 (UTC) 1894:05:27, 16 September 2013 (UTC) 1531:Edit request on 25 August 2013 1426:Molecular Weight Appears Wrong 1177:has a longer half-life and is 855:amitriptyline - Elavil, Levate 1: 5119:17:14, 23 February 2014 (UTC) 4967:10.1016/S0165-0173(01)00054-6 4919:10.1016/S0278-5846(02)00257-9 4402:Methamphetamine#Neurotoxicity 4000:10.1016/S0006-8993(97)01281-X 3446:10.1016/S0731-7085(02)00330-8 2861:19:40, 31 December 2013 (UTC) 1742:13:40, 8 September 2013 (UTC) 1160:15:47, 22 February 2013 (UTC) 1069:02:27, 22 February 2013 (UTC) 950:02:23, 22 February 2013 (UTC) 695:17:20, 27 December 2012 (UTC) 671:03:03, 26 December 2012 (UTC) 656:03:01, 26 December 2012 (UTC) 473:21:44, 10 February 2012 (UTC) 5174:00:56, 21 January 2014 (UTC) 4583:16:54, 6 February 2014 (UTC) 4305:22:51, 26 January 2014 (UTC) 4290:05:48, 20 January 2014 (UTC) 4260:04:07, 20 January 2014 (UTC) 4216:01:47, 20 January 2014 (UTC) 3960:Ghodse, Hamid (2002-08-15). 2917:Desoxyn Dec 2013 label info 2744:19:31, 3 November 2013 (UTC) 2339:23:07, 14 October 2013 (UTC) 1468:Although rarely prescribed, 1461:Some heavy editing requested 1325:Edit request on 27 July 2013 1255:Edit request on 23 July 2013 1137:15:05, 8 February 2013 (UTC) 1038:03:06, 3 February 2013 (UTC) 919:03:09, 3 February 2013 (UTC) 797:17:40, 20 January 2013 (UTC) 782:12:16, 16 January 2013 (UTC) 446:01:41, 9 December 2012 (UTC) 430:22:05, 24 January 2012 (UTC) 390:21:24, 24 January 2012 (UTC) 375:21:16, 24 January 2012 (UTC) 348:21:42, 23 January 2012 (UTC) 324:21:12, 23 January 2012 (UTC) 296:20:32, 23 January 2012 (UTC) 248:17:45, 23 January 2012 (UTC) 220:17:14, 23 January 2012 (UTC) 155:13:07, 17 January 2012 (UTC) 136:15:14, 14 January 2012 (UTC) 116:12:35, 11 January 2012 (UTC) 4200:03:24, 6 January 2014 (UTC) 4158:17:51, 2 January 2014 (UTC) 4128:12:43, 2 January 2014 (UTC) 4095:17:51, 2 January 2014 (UTC) 4060:08:57, 2 January 2014 (UTC) 3942:08:19, 2 January 2014 (UTC) 3891:06:52, 2 January 2014 (UTC) 3862:17:51, 2 January 2014 (UTC) 3832:00:32, 1 January 2014 (UTC) 3811:00:29, 1 January 2014 (UTC) 3797:00:27, 1 January 2014 (UTC) 2775:01:29, 6 January 2014 (UTC) 2718:10:06, 20 August 2014 (UTC) 2212:Methamphetamine and society 1926:Retrieved chemical sections 1659:07:47, 25 August 2013 (UTC) 1619:03:40, 25 August 2013 (UTC) 1602:02:41, 25 August 2013 (UTC) 1561:to reactivate your request. 1549:has been answered. Set the 1522:21:46, 23 August 2013 (UTC) 1451:19:00, 11 August 2013 (UTC) 1355:to reactivate your request. 1343:has been answered. Set the 1285:to reactivate your request. 1273:has been answered. Set the 1105:to reactivate your request. 1093:has been answered. Set the 986:to reactivate your request. 974:has been answered. Set the 873:guanfacine - Intuniv, Tenex 833:to reactivate your request. 821:has been answered. Set the 762:12:32, 5 January 2013 (UTC) 727:00:37, 2 January 2013 (UTC) 634:18:40, 21 August 2012 (UTC) 620:18:36, 21 August 2012 (UTC) 604:18:32, 21 August 2012 (UTC) 5665: 5649:22:34, 24 April 2014 (UTC) 5607:15:54, 24 April 2014 (UTC) 5525:02:52, 15 April 2014 (UTC) 5487:02:46, 15 April 2014 (UTC) 5458:01:46, 15 April 2014 (UTC) 5429:01:18, 15 April 2014 (UTC) 5396:20:21, 14 April 2014 (UTC) 4458:magnetic resonance imaging 2935:Methamphetamine synthesis 1664: 1570:personal attack collapsed 1250:21:51, 5 August 2013 (UTC) 1075:Edit Request, February 7th 876:lisdexamfetamine - Vyvanse 513:03:09, 25 April 2012 (UTC) 498:17:58, 17 March 2012 (UTC) 407:. That is quite possibly 5561:14:17, 20 July 2014 (UTC) 5357:14:24, 20 July 2014 (UTC) 5333:14:14, 20 July 2014 (UTC) 5298:05:30, 20 July 2014 (UTC) 5281:02:15, 2 April 2014 (UTC) 5250:15:55, 6 March 2014 (UTC) 5201:06:19, 1 March 2014 (UTC) 4361:) 04:48, 6 February 2014 2790:15:24, 20 July 2014 (UTC) 1420:17:28, 27 July 2013 (UTC) 1404:08:01, 27 July 2013 (UTC) 1319:22:13, 23 July 2013 (UTC) 1304:21:46, 23 July 2013 (UTC) 1235:08:07, 19 July 2013 (UTC) 1165:L-methamphetamine effects 879:methamphetamine - Desoxyn 585:File:Methamphetamine2.png 578:08:30, 12 July 2012 (UTC) 543:21:15, 9 April 2012 (UTC) 4268:addresses your concern. 3870:Radical (IMHO) deletions 3816:There is such a list at 2923:Pubchem Methamphetamine 1919:Please do not modify it. 1853:Routes of administration 1759:Please do not modify it. 1639:Knowledge isn't censored 1578:Please do not modify it. 563:11:14, 29 May 2012 (UTC) 405:that paper you mentioned 4870:10.1124/jpet.105.096503 861:atomoxetine - Strattera 5151: 5132:after copyediting it. 4534: 4516: 4475:, marked shrinkage of 4445: 4441:post acute withdrawals 3434:J. Pharm. Biomed. Anal 2906: 2893: 2880: 2646:Check date values in: 2565:Check date values in: 2484:Check date values in: 2180:Methamphetamine as an 184:Trauma: Life in the ER 5146: 5136:76.206.202.48 posted 4530:right caudate nucleus 4525: 4479:, and a reduction in 4454: 4406: 2905: 2892: 2879: 2724:North Korean Epidemic 2171:I would suggest that 2053:Methamphetamine slang 1879:- move entire section 1873:- move entire section 1867:- move entire section 1861:- move entire section 1855:- move entire section 1843:- move entire section 1841:Ambulance attendances 1837:- move entire section 1825:- move entire section 1781:broaden the scope of 768:Incorrect information 42:of past discussions. 5140:on 19 January 2014 ( 5068:10.4088/JCP.12r08287 4506:as well as elevated 3564:Ann. N. Y. Acad. Sci 1835:Illegal laboratories 1643:persuade other users 403:. I just looked at 182:(Have you ever seen 18:Talk:Methamphetamine 5583:, like there is on 5056:J. Clin. Psychiatry 4418:Parkinson's disease 3783:Slang / Other Names 2167:Organizational idea 1641:, so you'd need to 1175:levomethamphetamine 1116:toward increases." 411:publication I have 334:Um, you seem to be 226:I'm satisfied with 5212:water intoxication 4742:10.1007/BF03033289 4022:Unknown parameter 3598:Unknown parameter 3543:Unknown parameter 3494:Miller GM (2011). 3468:Unknown parameter 3367:Unknown parameter 2995:Unknown parameter 2907: 2894: 2881: 2658:Unknown parameter 2577:Unknown parameter 2496:Unknown parameter 2217: 2182:ingested substance 1871:Illicit production 1859:Natural occurrence 1040:ChemistryWikiWiki 921:ChemistryWikiWiki 5577:illegal synthesis 5571:Illegal Synthesis 5284: 5267:comment added by 5216:salt intoxication 5142:view all feedback 4764:Acta Med. Okayama 4613:978-0-07-148127-4 4540: 4539: 4493:paralimbic cortex 4363: 4349:comment added by 4166:More or less done 3972:978-0-521-00001-7 3346:. 2013. pp. 12–13 3291:"Methamphetamine" 3245:"Methamphetamine" 3199:"Methamphetamine" 3153:"Methamphetamine" 3107:"Methamphetamine" 3061:"Methamphetamine" 3015:"Methamphetamine" 2708:comment added by 2215: 2086:is disjoint from 2021:dextroamphetamine 1647:Knowledge Commons 1594:Tyson.kaemmer9411 1591: 1590: 1565: 1564: 1454: 1437:comment added by 1359: 1358: 1289: 1288: 1109: 1108: 1030:ChemistryWikiWiki 990: 989: 911:ChemistryWikiWiki 903:ChemistryWikiWiki 888:pemoline - Cylert 837: 836: 752:comment added by 730: 713:comment added by 685:comment added by 541: 463:comment added by 191: 95: 94: 54: 53: 48:current talk page 5656: 5630: 5626: 5621: 5617: 5616: 5541: 5506: 5502: 5483: 5480: 5477: 5474: 5471: 5468: 5455: 5446: 5410: 5406: 5392: 5389: 5386: 5383: 5380: 5377: 5313: 5283: 5261: 5231: 5227: 5208:talk:amphetamine 5161: 5157: 5124:Reader feedback. 5102: 5101: 5095: 5087: 5078: 5047: 5041: 5040: 5034: 5026: 4998: 4992: 4991: 4985: 4977: 4950: 4944: 4943: 4937: 4929: 4913:(6): 1177–1183. 4901: 4895: 4894: 4888: 4880: 4864:(3): 1210–1218. 4852: 4846: 4845: 4825: 4794: 4779: 4778: 4759: 4753: 4752: 4725: 4719: 4718: 4712: 4704: 4687: 4678: 4672: 4671: 4655:(7): 1085–1099. 4644: 4635: 4634: 4628: 4620: 4600: 4564: 4560: 4500:-acetylaspartate 4485:cingulate cortex 4388: 4362: 4343: 4277: 4273: 4247: 4243: 4187: 4183: 4145: 4141: 4082: 4078: 4039: 4038: 4031: 4025: 4020: 4018: 4010: 3983: 3977: 3976: 3957: 3929: 3925: 3849: 3845: 3775: 3774: 3768: 3764: 3762: 3754: 3752: 3750: 3743:PubChem Compound 3735: 3729: 3728: 3722: 3718: 3716: 3708: 3706: 3704: 3689: 3683: 3682: 3676: 3672: 3670: 3662: 3660: 3658: 3643: 3637: 3636: 3634: 3632: 3622: 3614: 3608: 3607: 3601: 3596: 3594: 3586: 3559: 3553: 3552: 3546: 3541: 3539: 3531: 3522: 3491: 3485: 3484: 3477: 3471: 3466: 3464: 3456: 3429: 3423: 3422: 3416: 3412: 3410: 3402: 3400: 3398: 3391:Pubchem Compound 3383: 3377: 3376: 3370: 3365: 3363: 3355: 3353: 3351: 3341: 3333: 3327: 3326: 3320: 3316: 3314: 3306: 3304: 3302: 3295:PubChem Compound 3287: 3281: 3280: 3274: 3270: 3268: 3260: 3258: 3256: 3249:PubChem Compound 3241: 3235: 3234: 3228: 3224: 3222: 3214: 3212: 3210: 3203:PubChem Compound 3195: 3189: 3188: 3182: 3178: 3176: 3168: 3166: 3164: 3149: 3143: 3142: 3136: 3132: 3130: 3122: 3120: 3118: 3103: 3097: 3096: 3090: 3086: 3084: 3076: 3074: 3072: 3057: 3051: 3050: 3044: 3040: 3038: 3030: 3028: 3026: 3011: 3005: 3004: 2998: 2993: 2991: 2983: 2981: 2979: 2969: 2961: 2848: 2844: 2834: 2826: 2825: 2824: 2818: 2762: 2758: 2720: 2684: 2678: 2672: 2671: 2665: 2661: 2655: 2649: 2643: 2637: 2633: 2629: 2627: 2619: 2600: 2591: 2590: 2584: 2580: 2574: 2568: 2562: 2556: 2552: 2548: 2546: 2538: 2519: 2510: 2509: 2503: 2499: 2493: 2487: 2481: 2475: 2471: 2467: 2465: 2457: 2438: 2432: 2427: 2421: 2416: 2410: 2405: 2399: 2394: 2388: 2383: 2377: 2372: 2366: 2361: 2288:from that page? 1823:Recreational use 1761: 1629: 1628: 1580: 1567: 1556: 1552: 1542: 1541: 1535: 1453: 1431: 1350: 1346: 1336: 1335: 1329: 1280: 1276: 1266: 1265: 1259: 1100: 1096: 1086: 1085: 1079: 1066: 1061: 1056: 1048: 1047: 981: 977: 967: 966: 960: 947: 942: 937: 929: 928: 828: 824: 814: 813: 807: 764: 729: 707: 697: 529: 495: 487: 484: 475: 181: 81: 56: 55: 33: 32: 26: 5664: 5663: 5659: 5658: 5657: 5655: 5654: 5653: 5628: 5624: 5614: 5612: 5573: 5537: 5504: 5500: 5481: 5478: 5475: 5472: 5469: 5466: 5408: 5404: 5390: 5387: 5384: 5381: 5378: 5375: 5369: 5309: 5262: 5258: 5229: 5225: 5181: 5159: 5155: 5126: 5107: 5106: 5105: 5088: 5049: 5048: 5044: 5027: 5004:JAMA Psychiatry 5000: 4999: 4995: 4978: 4952: 4951: 4947: 4930: 4903: 4902: 4898: 4881: 4854: 4853: 4849: 4796: 4795: 4782: 4761: 4760: 4756: 4727: 4726: 4722: 4705: 4685: 4680: 4679: 4675: 4646: 4645: 4638: 4621: 4614: 4602: 4601: 4594: 4562: 4558: 4541: 4393: 4378:pharmacodynamic 4344: 4319: 4275: 4271: 4245: 4241: 4185: 4181: 4168: 4143: 4139: 4107: 4080: 4076: 4044: 4043: 4042: 4032: 4021: 4011: 3994:(1–2): 219–27. 3985: 3984: 3980: 3973: 3959: 3958: 3954: 3927: 3923: 3872: 3847: 3843: 3785: 3780: 3779: 3778: 3765: 3755: 3748: 3746: 3737: 3736: 3732: 3719: 3709: 3702: 3700: 3691: 3690: 3686: 3673: 3663: 3656: 3654: 3645: 3644: 3640: 3630: 3628: 3620: 3616: 3615: 3611: 3597: 3587: 3561: 3560: 3556: 3542: 3532: 3493: 3492: 3488: 3478: 3467: 3457: 3431: 3430: 3426: 3413: 3403: 3396: 3394: 3385: 3384: 3380: 3366: 3356: 3349: 3347: 3339: 3335: 3334: 3330: 3317: 3307: 3300: 3298: 3289: 3288: 3284: 3271: 3261: 3254: 3252: 3243: 3242: 3238: 3225: 3215: 3208: 3206: 3197: 3196: 3192: 3179: 3169: 3162: 3160: 3151: 3150: 3146: 3133: 3123: 3116: 3114: 3105: 3104: 3100: 3087: 3077: 3070: 3068: 3059: 3058: 3054: 3041: 3031: 3024: 3022: 3013: 3012: 3008: 2994: 2984: 2977: 2975: 2967: 2963: 2962: 2958: 2914: 2868: 2846: 2842: 2828: 2822: 2812: 2800: 2760: 2756: 2753:at this point. 2726: 2703: 2694: 2689: 2688: 2687: 2679: 2675: 2657: 2645: 2630: 2620: 2602: 2601: 2594: 2576: 2564: 2549: 2539: 2521: 2520: 2513: 2495: 2483: 2468: 2458: 2440: 2439: 2435: 2428: 2424: 2417: 2413: 2406: 2402: 2395: 2391: 2384: 2380: 2373: 2369: 2362: 2358: 2346: 2327: 2209: 2197: 2185: 2169: 2088:Methamphetamine 1928: 1923: 1922: 1775: 1757: 1750: 1667: 1626: 1576: 1554: 1550: 1539: 1533: 1514:Mister Infamous 1502: 1496: 1490: 1483: 1476: 1469: 1463: 1432: 1428: 1348: 1344: 1333: 1327: 1296:139.218.218.187 1278: 1274: 1263: 1257: 1167: 1145: 1098: 1094: 1083: 1077: 1064: 1059: 1054: 1045: 979: 975: 964: 958: 945: 940: 935: 926: 826: 822: 811: 805: 770: 747: 736: 708: 703: 680: 644: 588: 550: 521: 491: 485: 482: 458: 454: 100: 77: 30: 22: 21: 20: 12: 11: 5: 5662: 5660: 5652: 5651: 5572: 5569: 5568: 5567: 5566: 5565: 5564: 5563: 5494: 5493: 5492: 5491: 5490: 5489: 5368: 5365: 5364: 5363: 5362: 5361: 5360: 5359: 5338: 5337: 5336: 5335: 5301: 5300: 5257: 5254: 5253: 5252: 5180: 5177: 5135: 5125: 5122: 5104: 5103: 5062:(9): 902–917. 5042: 5010:(2): 185–198. 4993: 4945: 4896: 4847: 4841: 4839: 4837: 4809:(2): 379–407. 4803:Brain Res. Rev 4780: 4770:(3): 141–150. 4754: 4736:(3): 181–195. 4720: 4696:(6): 966–977. 4673: 4636: 4612: 4591: 4590: 4586: 4553: 4552: 4545: 4538: 4537: 4536: 4535: 4523: 4517: 4469:hyperintensity 4452: 4446: 4404: 4395: 4394: 4392:Article quotes 4391: 4386: 4385: 4384: 4381: 4373: 4372: 4318: 4315: 4314: 4313: 4312: 4311: 4310: 4309: 4308: 4307: 4227:neuroendocrine 4167: 4164: 4163: 4162: 4161: 4160: 4106: 4103: 4102: 4101: 4100: 4099: 4098: 4097: 4065: 4064: 4063: 4062: 4041: 4040: 3978: 3971: 3951: 3950: 3946: 3945: 3944: 3918: 3871: 3868: 3867: 3866: 3865: 3864: 3835: 3834: 3784: 3781: 3777: 3776: 3730: 3684: 3638: 3609: 3554: 3506:(2): 164–176. 3486: 3440:(2): 247–255. 3424: 3378: 3328: 3282: 3236: 3190: 3144: 3098: 3052: 3006: 2955: 2954: 2950: 2948: 2945: 2943: 2942: 2939: 2936: 2933: 2930: 2927: 2924: 2921: 2918: 2913: 2910: 2909: 2908: 2900: 2895: 2887: 2882: 2874: 2867: 2864: 2838: 2837: 2827: 2811: 2799: 2796: 2795: 2794: 2793: 2792: 2725: 2722: 2693: 2690: 2686: 2685: 2673: 2592: 2530:(2): 1308–17. 2511: 2433: 2422: 2411: 2400: 2389: 2378: 2367: 2355: 2354: 2350: 2345: 2342: 2326: 2323: 2322: 2321: 2320: 2319: 2301: 2300: 2281: 2280: 2279: 2278: 2260: 2259: 2208: 2205: 2196: 2193: 2184: 2178: 2168: 2165: 2164: 2163: 2162: 2161: 2160: 2159: 2158: 2157: 2156: 2155: 2154: 2153: 2152: 2151: 2028: 2011: 2010: 2009: 2008: 1976: 1975: 1927: 1924: 1916: 1915: 1914: 1884: 1881: 1880: 1874: 1868: 1862: 1856: 1850: 1844: 1838: 1832: 1826: 1818: 1810: 1809: 1806: 1793: 1774: 1773: 1772: 1771: 1770: 1752: 1751: 1749: 1748:Split sections 1746: 1745: 1744: 1729: 1728: 1727: 1715: 1697: 1696: 1693: 1685: 1666: 1663: 1662: 1661: 1623: 1622: 1621: 1589: 1588: 1582: 1581: 1572: 1571: 1563: 1562: 1543: 1532: 1529: 1528: 1527: 1500: 1494: 1488: 1480: 1474: 1467: 1462: 1459: 1457: 1427: 1424: 1423: 1422: 1394: 1364: 1357: 1356: 1337: 1326: 1323: 1322: 1321: 1287: 1286: 1267: 1256: 1253: 1220: 1216: 1215: 1210: 1204: 1194: 1191: 1190: 1166: 1163: 1144: 1141: 1140: 1139: 1107: 1106: 1087: 1076: 1073: 1072: 1071: 1012: 1011: 1003: 988: 987: 968: 957: 954: 953: 952: 894: 892: 890: 889: 886: 883: 880: 877: 874: 871: 868: 865: 862: 859: 856: 850: 847: 844: 842: 840: 835: 834: 815: 804: 801: 800: 799: 774:83.180.236.136 769: 766: 735: 732: 702: 699: 675: 643: 640: 639: 638: 637: 636: 587: 582: 581: 580: 570:203.97.127.101 549: 546: 520: 517: 516: 515: 500: 465:129.115.29.186 453: 450: 449: 448: 433: 432: 397: 396: 395: 394: 393: 392: 377: 362: 353: 352: 351: 350: 329: 328: 327: 326: 312:harm reduction 283: 275: 225: 223: 222: 203: 202: 201: 160: 159: 158: 157: 139: 138: 99: 96: 93: 92: 87: 82: 75: 70: 65: 62: 52: 51: 34: 23: 15: 14: 13: 10: 9: 6: 4: 3: 2: 5661: 5650: 5646: 5645: 5640: 5639: 5633: 5632: 5631: 5620: 5611: 5610: 5609: 5608: 5604: 5600: 5596: 5593: 5588: 5586: 5582: 5578: 5570: 5562: 5558: 5554: 5550: 5546: 5542: 5540: 5533: 5532: 5531: 5530: 5529: 5528: 5527: 5526: 5522: 5521: 5516: 5515: 5509: 5508: 5507: 5488: 5485: 5484: 5461: 5460: 5459: 5456: 5454: 5453: 5447: 5445: 5439: 5435: 5432: 5431: 5430: 5426: 5425: 5420: 5419: 5413: 5412: 5411: 5400: 5399: 5398: 5397: 5394: 5393: 5366: 5358: 5355: 5352: 5349: 5344: 5343: 5342: 5341: 5340: 5339: 5334: 5330: 5326: 5322: 5318: 5314: 5312: 5305: 5304: 5303: 5302: 5299: 5295: 5291: 5287: 5286: 5285: 5282: 5278: 5274: 5270: 5266: 5255: 5251: 5247: 5246: 5241: 5240: 5234: 5233: 5232: 5221: 5217: 5213: 5209: 5205: 5204: 5203: 5202: 5198: 5194: 5190: 5187: 5184: 5178: 5176: 5175: 5171: 5170: 5164: 5163: 5162: 5150: 5145: 5143: 5139: 5133: 5131: 5123: 5121: 5120: 5116: 5112: 5099: 5093: 5085: 5082: 5077: 5073: 5069: 5065: 5061: 5057: 5053: 5046: 5043: 5038: 5032: 5024: 5021: 5017: 5013: 5009: 5005: 4997: 4994: 4989: 4983: 4975: 4972: 4968: 4964: 4960: 4956: 4949: 4946: 4941: 4935: 4927: 4924: 4920: 4916: 4912: 4908: 4900: 4897: 4892: 4886: 4878: 4875: 4871: 4867: 4863: 4859: 4851: 4848: 4844: 4832: 4829: 4824: 4820: 4816: 4812: 4808: 4804: 4800: 4793: 4791: 4789: 4787: 4785: 4781: 4776: 4773: 4769: 4765: 4758: 4755: 4750: 4747: 4743: 4739: 4735: 4731: 4730:Neurotox. Res 4724: 4721: 4716: 4710: 4702: 4699: 4695: 4691: 4690:Pharmacol Rep 4684: 4677: 4674: 4669: 4666: 4662: 4658: 4654: 4650: 4643: 4641: 4637: 4632: 4626: 4619: 4615: 4610: 4606: 4599: 4597: 4593: 4589: 4585: 4584: 4580: 4579: 4574: 4573: 4567: 4566: 4565: 4550: 4546: 4543: 4542: 4533: 4531: 4524: 4522: 4518: 4515: 4513: 4509: 4505: 4501: 4499: 4494: 4490: 4489:limbic cortex 4486: 4482: 4478: 4474: 4470: 4467: 4463: 4459: 4453: 4451: 4447: 4444: 4442: 4438: 4435: 4431: 4430:neurotoxicity 4427: 4423: 4419: 4415: 4411: 4405: 4403: 4399: 4398: 4397: 4396: 4389: 4382: 4379: 4375: 4374: 4370: 4366: 4365: 4364: 4360: 4356: 4352: 4348: 4339: 4336: 4333: 4330: 4327: 4323: 4317:Not There Yet 4316: 4306: 4302: 4298: 4293: 4292: 4291: 4287: 4286: 4280: 4279: 4278: 4267: 4263: 4262: 4261: 4257: 4256: 4250: 4249: 4248: 4237: 4236:like this one 4233: 4228: 4224: 4219: 4218: 4217: 4213: 4209: 4204: 4203: 4202: 4201: 4197: 4196: 4190: 4189: 4188: 4177: 4173: 4165: 4159: 4155: 4154: 4148: 4147: 4146: 4134: 4133: 4132: 4131: 4130: 4129: 4125: 4121: 4117: 4113: 4104: 4096: 4092: 4091: 4085: 4084: 4083: 4071: 4070: 4069: 4068: 4067: 4066: 4061: 4057: 4053: 4048: 4047: 4046: 4045: 4036: 4029: 4016: 4008: 4005: 4001: 3997: 3993: 3989: 3982: 3979: 3974: 3969: 3965: 3964: 3956: 3953: 3949: 3943: 3939: 3938: 3932: 3931: 3930: 3919: 3916: 3915:catecholamine 3912: 3908: 3903: 3899: 3895: 3894: 3893: 3892: 3888: 3884: 3880: 3876: 3869: 3863: 3859: 3858: 3852: 3851: 3850: 3839: 3838: 3837: 3836: 3833: 3829: 3825: 3824: 3819: 3815: 3814: 3813: 3812: 3808: 3804: 3799: 3798: 3794: 3790: 3782: 3772: 3760: 3744: 3740: 3739:"Amphetamine" 3734: 3731: 3726: 3714: 3698: 3694: 3693:"Amphetamine" 3688: 3685: 3680: 3668: 3652: 3648: 3647:"Amphetamine" 3642: 3639: 3626: 3619: 3613: 3610: 3605: 3592: 3584: 3581: 3577: 3573: 3569: 3565: 3558: 3555: 3550: 3537: 3529: 3526: 3521: 3517: 3513: 3509: 3505: 3501: 3497: 3490: 3487: 3482: 3475: 3462: 3454: 3451: 3447: 3443: 3439: 3435: 3428: 3425: 3420: 3408: 3392: 3388: 3387:"Amphetamine" 3382: 3379: 3374: 3361: 3345: 3338: 3332: 3329: 3324: 3312: 3296: 3292: 3286: 3283: 3278: 3266: 3250: 3246: 3240: 3237: 3232: 3220: 3204: 3200: 3194: 3191: 3186: 3174: 3158: 3154: 3148: 3145: 3140: 3128: 3112: 3108: 3102: 3099: 3094: 3082: 3066: 3062: 3056: 3053: 3048: 3036: 3020: 3016: 3010: 3007: 3002: 2989: 2973: 2966: 2960: 2957: 2953: 2949: 2946: 2940: 2937: 2934: 2932:VMAT2 review 2931: 2929:TAAR1 review 2928: 2925: 2922: 2919: 2916: 2915: 2911: 2904: 2899: 2896: 2891: 2886: 2883: 2878: 2873: 2870: 2869: 2865: 2863: 2862: 2858: 2857: 2851: 2850: 2849: 2832: 2816: 2809: 2807: 2802: 2797: 2791: 2788: 2785: 2782: 2778: 2777: 2776: 2772: 2771: 2765: 2764: 2763: 2752: 2748: 2747: 2746: 2745: 2741: 2737: 2734: 2731: 2723: 2721: 2719: 2715: 2711: 2710:71.222.170.54 2707: 2700: 2697: 2691: 2683: 2677: 2674: 2669: 2653: 2641: 2632:|access-date= 2625: 2617: 2614: 2611:(4): 403–20. 2610: 2606: 2599: 2597: 2593: 2588: 2572: 2560: 2551:|access-date= 2544: 2536: 2533: 2529: 2525: 2518: 2516: 2512: 2507: 2491: 2479: 2470:|access-date= 2463: 2455: 2452: 2448: 2444: 2437: 2434: 2431: 2426: 2423: 2420: 2415: 2412: 2409: 2404: 2401: 2398: 2393: 2390: 2387: 2382: 2379: 2376: 2371: 2368: 2365: 2360: 2357: 2353: 2349: 2343: 2341: 2340: 2336: 2332: 2324: 2318: 2314: 2310: 2305: 2304: 2303: 2302: 2299: 2295: 2291: 2286: 2283: 2282: 2277: 2273: 2269: 2264: 2263: 2262: 2261: 2258: 2254: 2250: 2246: 2242: 2239: 2238: 2237: 2236: 2232: 2228: 2224: 2219: 2213: 2206: 2204: 2201: 2194: 2192: 2189: 2183: 2179: 2177: 2174: 2166: 2150: 2146: 2142: 2138: 2134: 2130: 2126: 2122: 2121: 2120: 2116: 2112: 2107: 2106: 2105: 2101: 2097: 2093: 2089: 2085: 2081: 2077: 2072: 2071: 2070: 2066: 2062: 2058: 2054: 2050: 2049: 2043: 2042: 2041: 2037: 2033: 2029: 2026: 2022: 2017: 2016: 2015: 2014: 2013: 2012: 2007: 2003: 1999: 1994: 1989: 1984: 1980: 1979: 1978: 1977: 1974: 1970: 1966: 1962: 1958: 1953: 1952: 1951: 1950: 1946: 1942: 1938: 1934: 1925: 1920: 1913: 1909: 1905: 1904:99.153.64.179 1901: 1898: 1897: 1896: 1895: 1891: 1887: 1878: 1875: 1872: 1869: 1866: 1863: 1860: 1857: 1854: 1851: 1848: 1845: 1842: 1839: 1836: 1833: 1830: 1827: 1824: 1821: 1820: 1819: 1816: 1807: 1804: 1799: 1794: 1791: 1788: 1787: 1786: 1784: 1778: 1768: 1767: 1766: 1763: 1760: 1754: 1753: 1747: 1743: 1739: 1735: 1730: 1725: 1721: 1716: 1713: 1709: 1704: 1703: 1702: 1701: 1700: 1694: 1691: 1686: 1684: 1680: 1676: 1675: 1674: 1672: 1660: 1656: 1652: 1648: 1644: 1640: 1636: 1632: 1624: 1620: 1616: 1612: 1608: 1607: 1606: 1605: 1604: 1603: 1599: 1595: 1587: 1584: 1583: 1579: 1574: 1573: 1569: 1568: 1560: 1557:parameter to 1548: 1544: 1537: 1536: 1530: 1526: 1525: 1524: 1523: 1519: 1515: 1509: 1505: 1499: 1493: 1487: 1479: 1473: 1466: 1460: 1458: 1455: 1452: 1448: 1444: 1440: 1436: 1425: 1421: 1417: 1413: 1408: 1407: 1406: 1405: 1401: 1397: 1392: 1390: 1386: 1382: 1378: 1374: 1370: 1367: 1362: 1354: 1351:parameter to 1342: 1338: 1331: 1330: 1324: 1320: 1316: 1312: 1308: 1307: 1306: 1305: 1301: 1297: 1293: 1284: 1281:parameter to 1272: 1268: 1261: 1260: 1254: 1252: 1251: 1247: 1243: 1237: 1236: 1232: 1228: 1224: 1214: 1211: 1209: 1205: 1203: 1200: 1199: 1198: 1195: 1188: 1184: 1180: 1176: 1172: 1171: 1170: 1164: 1162: 1161: 1157: 1153: 1150: 1142: 1138: 1134: 1130: 1126: 1125: 1124: 1121: 1117: 1113: 1104: 1101:parameter to 1092: 1088: 1081: 1080: 1074: 1070: 1067: 1062: 1057: 1051: 1043: 1042: 1041: 1039: 1035: 1031: 1026: 1023: 1021: 1016: 1009: 1008: 1007: 1006: 1000: 997: 993: 985: 982:parameter to 973: 969: 962: 961: 955: 951: 948: 943: 938: 932: 924: 923: 922: 920: 916: 912: 908: 904: 900: 897: 887: 884: 881: 878: 875: 872: 869: 866: 863: 860: 857: 854: 853: 852: 832: 829:parameter to 820: 816: 809: 808: 802: 798: 794: 790: 789:ButOnMethItIs 786: 785: 784: 783: 779: 775: 767: 765: 763: 759: 755: 754:196.2.126.176 751: 746: 742: 739: 733: 731: 728: 724: 720: 716: 712: 700: 698: 696: 692: 688: 687:74.93.162.113 684: 677: 673: 672: 668: 664: 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