604:
Moffat FL, Pinsky CM, Hammershaimb L, Petrelli NJ, Patt YZ, Whaley FS, Goldenberg DM (August 1996). "Clinical utility of external immunoscintigraphy with the IMMU-4 technetium-99m Fab' antibody fragment in patients undergoing surgery for carcinoma of the colon and rectum: results of a pivotal, phase
486:"Detection of blood-borne cells in colorectal cancer patients by nested reverse transcription-polymerase chain reaction for carcinoembryonic antigen messenger RNA: longitudinal analyses and demonstration of its potential importance as an adjunct to multiple serum markers"
515:
Behr T, Becker W, Hannappel E, Goldenberg DM, Wolf F (December 1995). "Targeting of liver metastases of colorectal cancer with IgG, F(ab')2, and Fab' anti-carcinoembryonic antigen antibodies labeled with 99mTc: the role of metabolism and kinetics".
548:
Primus FJ, Newell KD, Blue A, Goldenberg DM (February 1983). "Immunological heterogeneity of carcinoembryonic antigen: antigenic determinants on carcinoembryonic antigen distinguished by monoclonal antibodies".
656:
396:
for patients with known allergies or hypersensitivity to mouse proteins, as well as during pregnancy. Women should pause breast feeding for 24 hours after application of the drug.
570:
Hansen HJ, Jones AL, Sharkey RM, Grebenau R, Blazejewski N, Kunz A, et al. (February 1990). "Preclinical evaluation of an "instant" 99mTc-labeling kit for antibody imaging".
89:
1685:
649:
1458:
373:
2690:
34:
2094:
642:
416:. High doses of IMMU-4 (up to 20-fold diagnostic arcitumomab dose) have not led to any serious events. One patient has been reported to develop a
2626:
2295:
866:
2515:
1678:
1009:
2152:
2079:
1984:
1026:
2685:
2009:
1021:
870:
806:
757:
695:
368:
in 95% of colorectal cancers. Consequently, the antibody accumulates in such tumours together with the radioisotope, which emits
1671:
119:
965:
955:
898:
691:
2680:
2670:
2099:
802:
1958:
1409:
1087:
1004:
960:
893:
227:
459:
2643:
1104:
928:
591:
Hughes K (1995). "Use of radioimmunodetection with CEAScan in planning for resection of recurrent colorectal cancer".
20:
1737:
1040:
2202:
1379:
409:
1175:
1082:
908:
361:
63:
2675:
2631:
2598:
2539:
2490:
2405:
2029:
75:
2569:
2559:
2529:
2320:
2265:
2192:
2182:
2059:
679:
413:
1343:
2544:
2533:
2495:
2385:
2370:
2300:
2280:
2275:
2054:
1808:
1313:
1240:
365:
338:
2395:
2255:
2024:
1989:
1433:
1359:
1354:
1273:
918:
780:
377:
349:
153:
2510:
2480:
2475:
2460:
2290:
2137:
2089:
2049:
1694:
485:
424:
291:
171:
46:
27:
1748:
2232:
1783:
1743:
1424:
1298:
1293:
1158:
1142:
1111:
1077:
881:
844:
734:
344:
Before application, arcitumomab is reconstituted with a solution of the radioactive agent sodium
1364:
1303:
2119:
1938:
1399:
1288:
1283:
1235:
1205:
730:
710:
666:
622:
579:
558:
525:
497:
279:
404:
Only mild and transient side effects have been observed, mostly immunological reactions like
817:
720:
715:
705:
614:
484:
Guadagni F, Kantor J, Aloe S, Carone MD, Spila A, D'Alessandro R, et al. (March 2001).
287:
180:
135:
39:
236:
1172:
1092:
745:
393:
315:
143:
634:
2637:
2603:
2270:
1635:
1521:
1121:
994:
951:
889:
862:
798:
753:
687:
303:
2664:
2485:
2340:
1893:
1728:
1338:
1261:
1188:
345:
2500:
2465:
2450:
2445:
2440:
2435:
2410:
2365:
2360:
2355:
2350:
2335:
2222:
2197:
2177:
2039:
2004:
1943:
1923:
1733:
1718:
1663:
1653:
1640:
1625:
1526:
1511:
1462:
1369:
1308:
1153:
939:
670:
405:
299:
283:
102:
97:
2608:
2582:
2577:
2549:
2525:
2520:
2455:
2430:
2420:
2390:
2380:
2345:
2330:
2315:
2305:
2285:
2260:
2245:
2217:
2167:
2162:
2157:
2142:
2132:
2109:
2104:
2074:
2019:
1963:
1953:
1928:
1918:
1913:
1908:
1883:
1858:
1848:
1843:
1838:
1828:
1813:
1798:
1793:
1778:
1773:
1763:
1758:
1753:
1723:
1630:
1620:
1610:
1605:
1570:
1555:
1516:
1506:
1471:
1429:
1328:
1256:
1210:
1072:
914:
857:
829:
726:
463:
82:
618:
2554:
2505:
2470:
2400:
2375:
2325:
2310:
2250:
2240:
2212:
2187:
2127:
2069:
2064:
1999:
1979:
1933:
1903:
1898:
1888:
1878:
1873:
1863:
1853:
1823:
1818:
1788:
1768:
1600:
1595:
1590:
1585:
1580:
1575:
1501:
1496:
1491:
1486:
1481:
1439:
1384:
1349:
1332:
1323:
1278:
1245:
1230:
1225:
1138:
1134:
1129:
1066:
1059:
1053:
1046:
1033:
1016:
976:
971:
924:
904:
776:
701:
381:
252:
211:
2425:
2415:
2207:
2172:
2147:
2084:
2044:
2034:
2014:
1948:
1868:
1833:
1803:
1645:
1615:
1565:
1560:
1550:
1531:
1476:
1450:
1414:
1268:
1250:
1194:
1184:
1099:
943:
852:
786:
417:
337:
fragment off the antibody. From this, the Fab' fragment is prepared by mild
501:
626:
583:
562:
529:
1703:
1168:
191:
200:
1317:
1200:
821:
428:
326:
58:
1454:
1404:
1389:
833:
369:
330:
319:
1418:
1374:
986:
768:
51:
1394:
1220:
1215:
791:
322:
1667:
638:
427:. Since the dose of an arcitumomab application is about 10 m
265:
376:(SPECT), high-resolution images showing localisation,
2591:
2568:
2231:
2118:
1972:
1711:
1702:
1449:
1167:
1152:
1120:
985:
938:
880:
843:
816:
767:
744:
678:
251:
246:
226:
210:
190:
170:
165:
152:
142:
134:
118:
113:
88:
74:
69:
57:
45:
33:
26:
179:
318:. Arcitumomab is a Fab' fragment of IMMU-4, a
1679:
650:
460:"CEA-Scan Summary of Product Characteristics"
412:, so there is the theoretical possibility of
278:is a drug used for the diagnostic imaging of
8:
19:
408:, itching and fever. Some patients develop
127:In general: ā (Prescription only)
1708:
1686:
1672:
1664:
1164:
657:
643:
635:
605:III trial. The Immunomedics Study Group".
374:single photon emission computed tomography
235:
440:
325:monoclonal antibody extracted from the
199:
1654:Therapeutic radiopharmaceuticals (V10)
18:
454:
452:
450:
448:
446:
444:
7:
101:
314:Technetium (Tc) arcitumomab is an
14:
2691:Monoclonal antibodies for tumors
431:, such an overdose is unlikely.
392:Technetium (Tc) arcitumomab is
384:of the tumour can be obtained.
462:. Immunomedics. Archived from
1:
607:Journal of Clinical Oncology
400:Adverse effects and overdose
410:human anti-mouse antibodies
276:Technetium (Tc) arcitumomab
21:Technetium (Tc) arcitumomab
2707:
619:10.1200/JCO.1996.14.8.2295
423:Radioactivity can lead to
247:Chemical and physical data
2621:
2203:Mirvetuximab soravtansine
1544:
524:(23 Suppl): 5777sā5785s.
294:(arcitumomab, trade name
261:
2686:Antibody-drug conjugates
593:Proc Amer Soc Clin Oncol
362:carcinoembryonic antigen
2599:Depatuxizumab mafodotin
2540:Tucotuzumab celmoleukin
2491:Rovalpituzumab tesirine
2406:Lorvotuzumab mertansine
2296:Clivatuzumab tetraxetan
1380:Gallium (Ga) gozetotide
929:Iodinated human albumin
364:(CEA), an antigen over-
360:Arcitumomab recognizes
2560:Vorsetuzumab mafodotin
2516:Tacatuzumab tetraxetan
2321:Denintuzumab mafodotin
2266:Bivatuzumab mertansine
2193:Loncastuximab tesirine
2183:Indatuximab ravtansine
2060:Naptumomab estafenatox
680:Central nervous system
578:(3 Suppl): 794sā798s.
414:anaphylactic reactions
2545:Vandortuzumab vedotin
2496:Sacituzumab govitecan
2386:Inotuzumab ozogamicin
2371:Gemtuzumab ozogamicin
2301:Cofetuzumab pelidotin
2281:Cantuzumab ravtansine
2276:Cantuzumab mertansine
2095:Nofetumomab merpentan
2055:Moxetumomab pasudotox
1809:Glembatumumab vedotin
1695:Monoclonal antibodies
1314:Fludeoxyglucose (18F)
1241:Pittsburgh compound B
882:Cardiovascular system
286:. It consists of the
2681:Technetium compounds
2671:Radiopharmaceuticals
2592:Chimeric + humanized
2396:Lifastuzumab vedotin
2256:Belantamab mafodotin
2025:Ibritumomab tiuxetan
1990:Anatumomab mafenatox
1360:Fluorothymidine F-18
1355:Fluoroestradiol F-18
1274:Desmethoxyfallypride
781:Sodium iodohippurate
667:radiopharmaceuticals
380:or progression, and
350:technetium generator
329:of mice. The enzyme
2511:Sofituzumab vedotin
2481:Polatuzumab vedotin
2476:Pinatuzumab vedotin
2461:Oportuzumab monatox
2291:Citatuzumab bogatox
2153:Derlotuximab biotin
2138:Brentuximab vedotin
2090:Taplitumomab paptox
2080:Satumomab pendetide
2050:Nacolomab tafenatox
1985:Altumomab pentetate
1344:Fluorodeoxysorbitol
1088:Fluoroethyltyrosine
1027:Satumomab pendetide
425:radiation poisoning
420:after application.
356:Mechanism of action
292:monoclonal antibody
28:Monoclonal antibody
23:
16:Pharmaceutical drug
2648:Never to phase III
2010:Capromab pendetide
1784:Enfortumab vedotin
1425:Piflufolastat F-18
1299:Flotufolastat F-18
1294:Flortaucipir (18F)
1112:Piflufolastat F-18
1083:Fluorodeoxyglucose
1022:Capromab pendetide
845:Respiratory system
735:Flutemetamol (18F)
333:cleaves the F(ab')
280:colorectal cancers
2658:
2657:
2617:
2616:
1939:Tisotumab vedotin
1661:
1660:
1540:
1539:
1434:Rubidium chloride
1400:N-Methylspiperone
1289:Florbetapir (18F)
1284:Florbetaben (18F)
1236:N-Methylspiperone
1067:Iobenguane (131I)
1054:Iobenguane (123I)
919:Rubidium chloride
731:Florbetapir (18F)
711:Iofetamine (123I)
388:Contraindications
273:
272:
2698:
2570:Rat/mouse hybrid
1709:
1688:
1681:
1674:
1665:
1165:
1064:
1051:
1038:
1010:Hynic-octreotide
818:Gastrointestinal
716:Iolopride (123I)
706:Ioflupane (123I)
659:
652:
645:
636:
630:
600:
587:
566:
534:
533:
512:
506:
505:
481:
475:
474:
472:
471:
456:
269:
268:
239:
203:
183:
157:
105:
24:
22:
2706:
2705:
2701:
2700:
2699:
2697:
2696:
2695:
2661:
2660:
2659:
2654:
2653:
2638:Clinical trials
2613:
2587:
2564:
2227:
2114:
1968:
1698:
1692:
1662:
1657:
1656:
1650:
1546:Isotopes used:
1536:
1445:
1156:
1148:
1143:Iodocholesterol
1116:
1093:Sodium fluoride
1062:
1049:
1036:
981:
934:
876:
839:
812:
763:
746:Skeletal system
740:
674:
663:
633:
613:(8): 2295ā305.
603:
590:
572:Cancer Research
569:
551:Cancer Research
547:
543:
541:Further reading
538:
537:
518:Cancer Research
514:
513:
509:
490:Cancer Research
483:
482:
478:
469:
467:
458:
457:
442:
437:
402:
394:contraindicated
390:
358:
336:
316:immunoconjugate
312:
264:
262:
242:
222:
206:
186:
155:
144:Bioavailability
136:Pharmacokinetic
130:
109:
77:
17:
12:
11:
5:
2704:
2702:
2694:
2693:
2688:
2683:
2678:
2676:Technetium-99m
2673:
2663:
2662:
2656:
2655:
2652:
2651:
2650:
2649:
2646:
2635:
2629:
2623:
2622:
2619:
2618:
2615:
2614:
2612:
2611:
2606:
2604:Duvortuxizumab
2601:
2595:
2593:
2589:
2588:
2586:
2585:
2580:
2574:
2572:
2566:
2565:
2563:
2562:
2557:
2552:
2547:
2542:
2537:
2523:
2518:
2513:
2508:
2503:
2498:
2493:
2488:
2483:
2478:
2473:
2468:
2463:
2458:
2453:
2448:
2443:
2438:
2433:
2428:
2423:
2418:
2413:
2408:
2403:
2398:
2393:
2388:
2383:
2378:
2373:
2368:
2363:
2358:
2353:
2348:
2343:
2338:
2333:
2328:
2323:
2318:
2313:
2308:
2303:
2298:
2293:
2288:
2283:
2278:
2273:
2271:Brontictuzumab
2268:
2263:
2258:
2253:
2248:
2243:
2237:
2235:
2229:
2228:
2226:
2225:
2220:
2215:
2210:
2205:
2200:
2195:
2190:
2185:
2180:
2175:
2170:
2165:
2160:
2155:
2150:
2145:
2140:
2135:
2130:
2124:
2122:
2116:
2115:
2113:
2112:
2107:
2102:
2097:
2092:
2087:
2082:
2077:
2072:
2067:
2062:
2057:
2052:
2047:
2042:
2037:
2032:
2027:
2022:
2017:
2012:
2007:
2002:
1997:
1992:
1987:
1982:
1976:
1974:
1970:
1969:
1967:
1966:
1961:
1956:
1951:
1946:
1941:
1936:
1931:
1926:
1921:
1916:
1911:
1906:
1901:
1896:
1891:
1886:
1881:
1876:
1871:
1866:
1861:
1856:
1851:
1846:
1841:
1836:
1831:
1826:
1821:
1816:
1811:
1806:
1801:
1796:
1791:
1786:
1781:
1776:
1771:
1766:
1761:
1756:
1751:
1746:
1741:
1738:+hyaluronidase
1731:
1726:
1721:
1715:
1713:
1706:
1700:
1699:
1693:
1691:
1690:
1683:
1676:
1668:
1659:
1658:
1651:
1649:
1648:
1643:
1638:
1636:technetium-99m
1633:
1628:
1623:
1618:
1613:
1608:
1603:
1598:
1593:
1588:
1583:
1578:
1573:
1568:
1563:
1558:
1553:
1547:
1545:
1542:
1541:
1538:
1537:
1535:
1534:
1529:
1524:
1519:
1514:
1509:
1504:
1499:
1494:
1489:
1484:
1479:
1474:
1468:
1466:
1447:
1446:
1444:
1443:
1437:
1427:
1422:
1412:
1407:
1402:
1397:
1392:
1387:
1382:
1377:
1372:
1367:
1362:
1357:
1352:
1347:
1341:
1336:
1326:
1321:
1311:
1306:
1301:
1296:
1291:
1286:
1281:
1276:
1271:
1266:
1265:
1264:
1254:
1248:
1243:
1238:
1233:
1228:
1223:
1218:
1213:
1208:
1203:
1198:
1192:
1181:
1179:
1162:
1150:
1149:
1147:
1146:
1132:
1126:
1124:
1122:Adrenal cortex
1118:
1117:
1115:
1114:
1109:
1108:
1107:
1097:
1096:
1095:
1090:
1085:
1080:
1070:
1057:
1044:
1031:
1030:
1029:
1024:
1014:
1013:
1012:
1007:
1002:
991:
989:
983:
982:
980:
979:
974:
969:
963:
958:
948:
946:
936:
935:
933:
932:
922:
912:
902:
896:
886:
884:
878:
877:
875:
874:
860:
855:
849:
847:
841:
840:
838:
837:
826:
824:
814:
813:
811:
810:
796:
795:
794:
784:
773:
771:
765:
764:
762:
761:
750:
748:
742:
741:
739:
738:
724:
718:
713:
708:
699:
684:
682:
676:
675:
664:
662:
661:
654:
647:
639:
632:
631:
601:
588:
567:
544:
542:
539:
536:
535:
507:
496:(6): 2523ā32.
476:
439:
438:
436:
433:
401:
398:
389:
386:
357:
354:
334:
311:
308:
304:technetium-99m
282:, marketed by
271:
270:
259:
258:
255:
249:
248:
244:
243:
241:
240:
232:
230:
224:
223:
221:
220:
216:
214:
208:
207:
205:
204:
196:
194:
188:
187:
185:
184:
176:
174:
168:
167:
163:
162:
159:
150:
149:
146:
140:
139:
132:
131:
129:
128:
124:
122:
116:
115:
111:
110:
108:
107:
94:
92:
86:
85:
80:
78:administration
72:
71:
67:
66:
61:
55:
54:
49:
43:
42:
37:
31:
30:
15:
13:
10:
9:
6:
4:
3:
2:
2703:
2692:
2689:
2687:
2684:
2682:
2679:
2677:
2674:
2672:
2669:
2668:
2666:
2647:
2645:
2642:
2641:
2639:
2636:
2633:
2630:
2628:
2625:
2624:
2620:
2610:
2607:
2605:
2602:
2600:
2597:
2596:
2594:
2590:
2584:
2581:
2579:
2576:
2575:
2573:
2571:
2567:
2561:
2558:
2556:
2553:
2551:
2548:
2546:
2543:
2541:
2538:
2535:
2531:
2527:
2524:
2522:
2519:
2517:
2514:
2512:
2509:
2507:
2504:
2502:
2499:
2497:
2494:
2492:
2489:
2487:
2486:Rosmantuzumab
2484:
2482:
2479:
2477:
2474:
2472:
2469:
2467:
2464:
2462:
2459:
2457:
2454:
2452:
2449:
2447:
2444:
2442:
2439:
2437:
2434:
2432:
2429:
2427:
2424:
2422:
2419:
2417:
2414:
2412:
2409:
2407:
2404:
2402:
2399:
2397:
2394:
2392:
2389:
2387:
2384:
2382:
2379:
2377:
2374:
2372:
2369:
2367:
2364:
2362:
2359:
2357:
2354:
2352:
2349:
2347:
2344:
2342:
2341:Enoblituzumab
2339:
2337:
2334:
2332:
2329:
2327:
2324:
2322:
2319:
2317:
2314:
2312:
2309:
2307:
2304:
2302:
2299:
2297:
2294:
2292:
2289:
2287:
2284:
2282:
2279:
2277:
2274:
2272:
2269:
2267:
2264:
2262:
2259:
2257:
2254:
2252:
2249:
2247:
2244:
2242:
2239:
2238:
2236:
2234:
2230:
2224:
2221:
2219:
2216:
2214:
2211:
2209:
2206:
2204:
2201:
2199:
2196:
2194:
2191:
2189:
2186:
2184:
2181:
2179:
2176:
2174:
2171:
2169:
2166:
2164:
2161:
2159:
2156:
2154:
2151:
2149:
2146:
2144:
2141:
2139:
2136:
2134:
2131:
2129:
2126:
2125:
2123:
2121:
2117:
2111:
2108:
2106:
2103:
2101:
2098:
2096:
2093:
2091:
2088:
2086:
2083:
2081:
2078:
2076:
2073:
2071:
2068:
2066:
2063:
2061:
2058:
2056:
2053:
2051:
2048:
2046:
2043:
2041:
2038:
2036:
2033:
2031:
2028:
2026:
2023:
2021:
2018:
2016:
2013:
2011:
2008:
2006:
2003:
2001:
1998:
1996:
1993:
1991:
1988:
1986:
1983:
1981:
1978:
1977:
1975:
1971:
1965:
1962:
1960:
1957:
1955:
1952:
1950:
1947:
1945:
1942:
1940:
1937:
1935:
1932:
1930:
1927:
1925:
1922:
1920:
1917:
1915:
1912:
1910:
1907:
1905:
1902:
1900:
1897:
1895:
1894:Pembrolizumab
1892:
1890:
1887:
1885:
1882:
1880:
1877:
1875:
1872:
1870:
1867:
1865:
1862:
1860:
1857:
1855:
1852:
1850:
1847:
1845:
1842:
1840:
1837:
1835:
1832:
1830:
1827:
1825:
1822:
1820:
1817:
1815:
1812:
1810:
1807:
1805:
1802:
1800:
1797:
1795:
1792:
1790:
1787:
1785:
1782:
1780:
1777:
1775:
1772:
1770:
1767:
1765:
1762:
1760:
1757:
1755:
1752:
1750:
1747:
1745:
1742:
1739:
1735:
1732:
1730:
1729:Ascrinvacumab
1727:
1725:
1722:
1720:
1717:
1716:
1714:
1710:
1707:
1705:
1701:
1696:
1689:
1684:
1682:
1677:
1675:
1670:
1669:
1666:
1655:
1647:
1644:
1642:
1639:
1637:
1634:
1632:
1629:
1627:
1624:
1622:
1619:
1617:
1614:
1612:
1609:
1607:
1604:
1602:
1599:
1597:
1594:
1592:
1589:
1587:
1584:
1582:
1579:
1577:
1574:
1572:
1569:
1567:
1564:
1562:
1559:
1557:
1554:
1552:
1549:
1548:
1543:
1533:
1530:
1528:
1525:
1523:
1520:
1518:
1515:
1513:
1510:
1508:
1505:
1503:
1500:
1498:
1495:
1493:
1490:
1488:
1485:
1483:
1480:
1478:
1475:
1473:
1470:
1469:
1467:
1464:
1460:
1456:
1452:
1448:
1441:
1438:
1435:
1431:
1428:
1426:
1423:
1420:
1416:
1413:
1411:
1408:
1406:
1403:
1401:
1398:
1396:
1393:
1391:
1388:
1386:
1383:
1381:
1378:
1376:
1373:
1371:
1368:
1366:
1363:
1361:
1358:
1356:
1353:
1351:
1348:
1345:
1342:
1340:
1339:Fluorocholine
1337:
1334:
1330:
1327:
1325:
1322:
1319:
1315:
1312:
1310:
1307:
1305:
1302:
1300:
1297:
1295:
1292:
1290:
1287:
1285:
1282:
1280:
1277:
1275:
1272:
1270:
1267:
1263:
1260:
1259:
1258:
1255:
1252:
1249:
1247:
1244:
1242:
1239:
1237:
1234:
1232:
1229:
1227:
1224:
1222:
1219:
1217:
1214:
1212:
1209:
1207:
1204:
1202:
1199:
1196:
1193:
1190:
1186:
1183:
1182:
1180:
1177:
1174:
1170:
1166:
1163:
1160:
1155:
1154:Radionuclides
1151:
1144:
1140:
1136:
1133:
1131:
1128:
1127:
1125:
1123:
1119:
1113:
1110:
1106:
1103:
1102:
1101:
1098:
1094:
1091:
1089:
1086:
1084:
1081:
1079:
1076:
1075:
1074:
1071:
1068:
1061:
1058:
1055:
1048:
1045:
1042:
1035:
1032:
1028:
1025:
1023:
1020:
1019:
1018:
1015:
1011:
1008:
1006:
1003:
1001:
998:
997:
996:
993:
992:
990:
988:
984:
978:
975:
973:
970:
967:
964:
962:
959:
957:
953:
950:
949:
947:
945:
941:
937:
930:
926:
923:
920:
916:
913:
910:
906:
903:
900:
897:
895:
891:
888:
887:
885:
883:
879:
872:
871:Pentetic acid
868:
864:
861:
859:
856:
854:
851:
850:
848:
846:
842:
835:
831:
828:
827:
825:
823:
819:
815:
808:
807:Pentetic acid
804:
800:
797:
793:
790:
789:
788:
785:
782:
778:
775:
774:
772:
770:
766:
759:
758:Medronic acid
755:
752:
751:
749:
747:
743:
736:
732:
728:
725:
722:
719:
717:
714:
712:
709:
707:
703:
700:
697:
696:Pentetic acid
693:
689:
686:
685:
683:
681:
677:
672:
668:
660:
655:
653:
648:
646:
641:
640:
637:
628:
624:
620:
616:
612:
608:
602:
598:
594:
589:
585:
581:
577:
573:
568:
564:
560:
557:(2): 686ā92.
556:
552:
546:
545:
540:
531:
527:
523:
519:
511:
508:
503:
499:
495:
491:
487:
480:
477:
466:on 2016-03-13
465:
461:
455:
453:
451:
449:
447:
445:
441:
434:
432:
430:
426:
421:
419:
415:
411:
407:
399:
397:
395:
387:
385:
383:
379:
375:
371:
367:
363:
355:
353:
351:
347:
346:pertechnetate
342:
340:
332:
328:
324:
321:
317:
309:
307:
305:
301:
297:
293:
289:
288:Fab' fragment
285:
281:
277:
267:
260:
256:
254:
250:
245:
238:
234:
233:
231:
229:
225:
218:
217:
215:
213:
209:
202:
198:
197:
195:
193:
189:
182:
178:
177:
175:
173:
169:
164:
160:
158:
151:
147:
145:
141:
137:
133:
126:
125:
123:
121:
117:
112:
104:
99:
96:
95:
93:
91:
87:
84:
81:
79:
73:
70:Clinical data
68:
65:
62:
60:
56:
53:
50:
48:
44:
41:
40:Fab' fragment
38:
36:
32:
29:
25:
2501:Sibrotuzumab
2466:Parsatuzumab
2451:Otlertuzumab
2446:Odronextamab
2441:Ocaratuzumab
2436:Obinutuzumab
2411:Lumretuzumab
2366:Flotetuzumab
2361:Ficlatuzumab
2356:Farletuzumab
2351:Etaracizumab
2336:Emibetuzumab
2223:Zolbetuximab
2198:Margetuximab
2178:Girentuximab
2040:Minretumomab
2005:Blinatumomab
1994:
1944:Teprotumumab
1924:Seribantumab
1749:Botensilimab
1734:Atezolizumab
1719:Adecatumumab
1641:thallium-201
1626:samarium-153
1463:scintigraphy
1370:Flutemetamol
1309:Fluciclovine
1078:Fluciclovine
1041:Minretumomab
999:
940:Inflammation
610:
606:
596:
592:
575:
571:
554:
550:
521:
517:
510:
493:
489:
479:
468:. Retrieved
464:the original
422:
406:eosinophilia
403:
391:
359:
348:(Tc) from a
343:
313:
300:radionuclide
295:
284:Immunomedics
275:
274:
263:
161:13 Ā± 4 hours
154:Elimination
120:Legal status
114:Legal status
2634:from market
2609:Ontuxizumab
2583:Ertumaxomab
2578:Catumaxomab
2550:Vanucizumab
2530:+deruxtecan
2526:Trastuzumab
2521:Tigatuzumab
2456:Onartuzumab
2431:Nimotuzumab
2421:Milatuzumab
2391:Labetuzumab
2381:Imgatuzumab
2346:Epcoritamab
2331:Emactuzumab
2316:Dalotuzumab
2306:Dacetuzumab
2286:Cirmtuzumab
2261:Bevacizumab
2246:Alemtuzumab
2218:Ublituximab
2168:Ensituximab
2163:Ecromeximab
2158:Dinutuximab
2143:Carotuximab
2133:Bavituximab
2110:Tositumomab
2105:Tenatumomab
2075:Racotumomab
2020:Edrecolomab
1995:Arcitumomab
1964:Zalutumumab
1954:Vantictumab
1929:Sugemalimab
1919:Robatumumab
1914:Rilotumumab
1909:Ramucirumab
1884:Panitumumab
1859:Necitumumab
1849:Mapatumumab
1844:Lucatumumab
1839:Lexatumumab
1829:Istiratumab
1814:Intetumumab
1799:Flanvotumab
1794:Figitumumab
1779:Dusigitumab
1774:Duligotumab
1764:Daratumumab
1759:Conatumumab
1754:Cixutumumab
1744:Balstilimab
1724:Amivantamab
1631:selenium-75
1621:rubidium-82
1611:nitrogen-13
1606:krypton-81m
1571:fluorine-18
1556:chromium-51
1211:Carfentanil
1157:(including
1000:Arcitumomab
966:Tilmanocept
956:Exametazime
899:Tetrofosmin
692:Exametazime
665:Diagnostic
257:54 kDa
181:154361-49-6
166:Identifiers
83:Intravenous
2665:Categories
2555:Veltuzumab
2534:+emtansine
2506:Simtuzumab
2471:Pertuzumab
2401:Lintuzumab
2376:Glofitamab
2326:Elotuzumab
2311:Demcizumab
2251:Axatilimab
2241:Abituzumab
2213:Siltuximab
2188:Isatuximab
2128:Amatuximab
2100:Pintumomab
2070:Pemtumomab
2065:Oregovomab
2000:Bectumomab
1980:Abagovomab
1934:Tarextumab
1904:Radretumab
1899:Pritumumab
1889:Patritumab
1879:Olaratumab
1874:Ofatumumab
1864:Nesvacumab
1854:Narnatumab
1824:Iratumumab
1819:Ipilimumab
1789:Enoticumab
1769:Drozitumab
1697:for tumors
1652:See also:
1601:iodine-131
1596:iodine-125
1591:iodine-123
1586:indium-111
1581:gallium-68
1576:gallium-67
1440:Setoperone
1365:Fluspidine
1350:Fluorodopa
1333:Altanserin
1324:Flumazenil
1279:Fallypride
1246:Raclopride
1231:Methionine
1226:Flumazenil
1197:(Cimbi-36)
803:Mertiatide
470:2009-10-28
435:References
382:metastases
253:Molar mass
237:029JF1SCU8
212:ChemSpider
172:CAS Number
2644:Phase III
2632:Withdrawn
2426:Naxitamab
2416:Matuzumab
2233:Humanized
2208:Rituximab
2173:Futuximab
2148:Cetuximab
2085:Solitomab
2045:Mitumomab
2035:Lilotomab
2015:Detumomab
1959:Votumumab
1949:Tovetumab
1869:Nivolumab
1834:Icrucumab
1804:Ganitumab
1646:xenon-133
1616:oxygen-15
1566:copper-64
1561:cobalt-57
1551:carbon-11
1451:gamma ray
1304:Flubatine
1251:Verapamil
1195:25B-NBOMe
1189:ME@HAPTHI
1005:Votumumab
961:Sulesomab
944:infection
909:Imciromab
894:Sestamibi
721:Iomazenil
418:grand mal
378:remission
366:expressed
339:reduction
310:Chemistry
156:half-life
76:Routes of
2120:Chimeric
2030:Igovomab
1320:analogue
1169:positron
1105:Dotatate
502:11289125
298:) and a
296:CEA-Scan
266:(verify)
192:DrugBank
90:ATC code
1318:glucose
1262:Ammonia
1206:Choline
1201:Acetate
1159:tracers
822:Hepatic
627:8708720
584:2297726
563:6184152
530:7493346
370:photons
327:ascites
201:DB00113
106:)
100: (
98:V09IA06
2627:WHO-EM
1455:photon
1405:Nifene
1390:Mefway
1316:(FDG)-
1063:
1050:
1037:
867:Tc-MAA
834:SeHCAT
625:
599:: 544.
582:
561:
528:
500:
372:. Via
331:pepsin
320:murine
59:Target
47:Source
1973:Mouse
1712:Human
1704:Tumor
1459:SPECT
1419:Water
1375:FMISO
1346:(FDS)
987:Tumor
769:Renal
290:of a
52:Mouse
1395:MPPF
1221:DTBZ
1216:DASB
1176:list
792:ETS2
623:PMID
580:PMID
559:PMID
526:PMID
498:PMID
323:IgG1
228:UNII
219:none
138:data
35:Type
1410:FET
1173:PET
671:V09
615:doi
148:N/A
103:WHO
64:CEA
2667::
2640::
2532:/
1532:Xe
1527:Tl
1522:Tc
1517:Se
1512:Sm
1507:Kr
1487:In
1482:Ga
1477:Co
1472:Cr
1430:Rb
1385:Ga
1269:Cu
1137:/
1100:Cu
1017:In
995:Tc
977:Ga
972:In
952:Tc
915:Rb
905:In
890:Tc
869:,
863:Tc
858:Kr
853:Xe
830:Se
805:,
799:Tc
787:Cu
754:Tc
733:,
694:,
688:Tc
621:.
611:14
609:.
597:14
595:.
576:50
574:.
555:43
553:.
522:55
520:.
494:61
492:.
488:.
443:^
429:Sv
352:.
341:.
306:.
302:,
2536:)
2528:(
1740:)
1736:(
1687:e
1680:t
1673:v
1502:I
1497:I
1492:I
1465:)
1461:/
1457:(
1453:/
1442:)
1436:)
1432:(
1421:)
1417:(
1415:O
1335:)
1331:(
1329:F
1257:N
1253:)
1191:)
1187:(
1185:C
1178:)
1171:(
1161:)
1145:)
1141:(
1139:I
1135:I
1130:I
1073:F
1069:)
1065:(
1060:I
1056:)
1052:(
1047:I
1043:)
1039:(
1034:I
968:)
954:(
942:/
931:)
927:(
925:I
921:)
917:(
911:)
907:(
901:)
892:(
873:)
865:(
836:)
832:(
820:/
809:)
801:(
783:)
779:(
777:I
760:)
756:(
737:)
729:(
727:F
723:)
704:(
702:I
698:)
690:(
673:)
669:(
658:e
651:t
644:v
629:.
617::
586:.
565:.
532:.
504:.
473:.
335:2
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