582:
974:
605:
34:
27:
600:
785:
Fishman J, Martucci CP (1980). "New
Concepts of Estrogenic Activity: the Role of Metabolites in the Expression of Hormone Action". In Pasetto N, Paoletti R, Ambrus JL (eds.).
1000:
625:
Martucci C, Fishman J (March 1976). "Uterine estrogen receptor binding of catecholestrogens and of estetrol (1,3,5(10)-estratriene-3,15alpha,16alpha,17beta-tetrol)".
668:
Martucci C, Fishman J (December 1977). "Direction of estradiol metabolism as a control of its hormonal action--uterotrophic activity of estradiol metabolites".
750:
Martucci CP, Fishman J (December 1979). "Impact of continuously administered catechol estrogens on uterine growth and luteinizing hormone secretion".
818:
Fishman J, Martucci C (September 1980). "Biological properties of 16 alpha-hydroxyestrone: implications in estrogen physiology and pathophysiology".
891:
Estrogens in the
Environment: Proceedings of the Symposium on Estrogens in the Environment, Raleigh, North Carolina, U.S.A., September 10-12, 1979
802:
568:). = Atypical uterotrophic effect which plateaus within 48 hours (estradiol's uterotrophy continues linearly up to 72 hours).
899:
556:
levels relative to baseline of ovariectomized rats after 24 to 72 hours of continuous administration via subcutaneous implant.
995:
888:
Fishman J, Martucci C (1980). "Dissociation of biological activities in metabolites of estradiol". In McLachlan JA (ed.).
97:
915:
Kuhl H (August 2005). "Pharmacology of estrogens and progestogens: influence of different routes of administration".
523:
105:
64:
138:
595:
204:
51:
43:
446:
542:
182:
160:
553:
86:
990:
936:
732:
650:
561:
314:
292:
270:
248:
928:
895:
870:
835:
798:
767:
724:
685:
642:
527:
336:
56:
920:
862:
827:
790:
759:
716:
677:
634:
490:
468:
424:
402:
380:
358:
704:
606:
Template:Relative affinities of estrogens for steroid hormone receptors and blood proteins
984:
866:
638:
940:
736:
654:
545:
889:
794:
538:
226:
81:
924:
565:
541:
rats after 72 hours with continuous administration of 1 μg/hour via
853:
Martucci CP (July 1983). "The role of 2-methoxyestrone in estrogen action".
763:
681:
932:
720:
576:
874:
839:
831:
771:
728:
689:
646:
534:
531:
75:
601:
Template:Affinities of estrogen receptor ligands for the ERα and ERβ
537:. Uterine weight = Percentage change in uterine wet weight of
705:"Differential biological activity of estradiol metabolites"
967:
959:
955:
820:
The
Journal of Clinical Endocrinology and Metabolism
98:
952:Editors can experiment in this template's sandbox
519:
106:
65:
42:Selected biological properties of endogenous
28:
8:
549:
87:
35:
21:
15:
516:
57:
1001:Templates that generate named references
703:Fishman J, Martucci C (December 1978).
617:
510:
16:
7:
596:Estrogen (medication) § Pharmacology
103:Tooltip Sex hormone-binding globulin
14:
111:Tooltip relative binding affinity
70:Tooltip relative binding affinity
580:
855:Journal of Steroid Biochemistry
787:The Menopause and Postmenopause
515:Values are mean ± SD or range.
894:. Elsevier. pp. 131–145.
1:
867:10.1016/0022-4731(83)90229-7
639:10.1016/0039-128x(76)90054-4
795:10.1007/978-94-011-7230-1_5
92:Tooltip Luteinizing hormone
1017:
951:
975:Subpages of this template
925:10.1080/13697130500148875
524:Relative binding affinity
511:
62:Tooltip Estrogen receptor
543:subcutaneously implanted
764:10.1210/endo-105-6-1288
682:10.1210/endo-101-6-1709
721:10.1542/peds.62.6.1128
585:Template documentation
832:10.1210/jcem-51-3-611
715:(6 Pt 2): 1128–1133.
996:Medication templates
919:. 8 Suppl 1: 3–63.
554:Luteinizing hormone
47:
789:. pp. 43–52.
528:estrogen receptors
447:16α-Hydroxyestrone
315:4-Methoxyestradiol
293:4-Hydroxyestradiol
271:2-Methoxyestradiol
249:2-Hydroxyestradiol
804:978-94-011-7232-5
575:
574:
337:4-Fluoroestradiol
1008:
971:
963:
945:
944:
912:
906:
905:
885:
879:
878:
850:
844:
843:
815:
809:
808:
782:
776:
775:
758:(6): 1288–1292.
747:
741:
740:
700:
694:
693:
676:(6): 1709–1715.
665:
659:
658:
622:
586:
584:
583:
551:
521:
518:
491:2-Methoxyestriol
469:2-Hydroxyestriol
425:4-Methoxyestrone
403:4-Hydroxyestrone
381:2-Methoxyestrone
359:2-Hydroxyestrone
112:
108:
104:
100:
93:
89:
71:
67:
63:
59:
48:
37:
30:
23:
1016:
1015:
1011:
1010:
1009:
1007:
1006:
1005:
981:
980:
979:
978:
973:
965:
953:
950:
949:
948:
914:
913:
909:
902:
887:
886:
882:
861:(1B): 635–638.
852:
851:
847:
817:
816:
812:
805:
784:
783:
779:
749:
748:
744:
702:
701:
697:
667:
666:
662:
624:
623:
619:
614:
592:
587:
581:
579:
110:
102:
91:
69:
61:
41:
12:
11:
5:
1014:
1012:
1004:
1003:
998:
993:
983:
982:
964:and testcases
947:
946:
907:
900:
880:
845:
826:(3): 611–615.
810:
803:
777:
742:
695:
660:
633:(3): 325–333.
616:
615:
613:
610:
609:
608:
603:
598:
591:
588:
578:
577:
573:
572:
539:ovariectomized
509:
508:
505:
502:
499:
496:
493:
487:
486:
483:
480:
477:
474:
471:
465:
464:
461:
458:
455:
452:
449:
443:
442:
439:
436:
433:
430:
427:
421:
420:
417:
414:
411:
408:
405:
399:
398:
395:
392:
389:
386:
383:
377:
376:
373:
370:
367:
364:
361:
355:
354:
351:
348:
345:
342:
339:
333:
332:
329:
326:
323:
320:
317:
311:
310:
307:
304:
301:
298:
295:
289:
288:
285:
282:
279:
276:
273:
267:
266:
263:
260:
257:
254:
251:
245:
244:
241:
238:
235:
232:
229:
223:
222:
219:
216:
213:
210:
207:
201:
200:
197:
194:
191:
188:
185:
179:
178:
175:
172:
169:
166:
163:
157:
156:
153:
150:
147:
144:
141:
139:Estradiol (E2)
135:
134:
131:
128:
125:
122:
119:
115:
114:
95:
84:
79:
76:Uterine weight
73:
54:
40:
39:
32:
25:
17:
13:
10:
9:
6:
4:
3:
2:
1013:
1002:
999:
997:
994:
992:
989:
988:
986:
976:
969:
961:
957:
942:
938:
934:
930:
926:
922:
918:
911:
908:
903:
901:9780444003720
897:
893:
892:
884:
881:
876:
872:
868:
864:
860:
856:
849:
846:
841:
837:
833:
829:
825:
821:
814:
811:
806:
800:
796:
792:
788:
781:
778:
773:
769:
765:
761:
757:
753:
752:Endocrinology
746:
743:
738:
734:
730:
726:
722:
718:
714:
710:
706:
699:
696:
691:
687:
683:
679:
675:
671:
670:Endocrinology
664:
661:
656:
652:
648:
644:
640:
636:
632:
628:
621:
618:
611:
607:
604:
602:
599:
597:
594:
593:
589:
571:
567:
563:
559:
555:
547:
546:osmotic pumps
544:
540:
536:
533:
529:
525:
514:
506:
503:
500:
497:
494:
492:
489:
488:
484:
481:
478:
475:
472:
470:
467:
466:
462:
459:
456:
453:
450:
448:
445:
444:
440:
437:
434:
431:
428:
426:
423:
422:
418:
415:
412:
409:
406:
404:
401:
400:
396:
393:
390:
387:
384:
382:
379:
378:
374:
371:
368:
365:
362:
360:
357:
356:
352:
349:
346:
343:
340:
338:
335:
334:
330:
327:
324:
321:
318:
316:
313:
312:
308:
305:
302:
299:
296:
294:
291:
290:
286:
283:
280:
277:
274:
272:
269:
268:
264:
261:
258:
255:
252:
250:
247:
246:
242:
239:
236:
233:
230:
228:
227:17α-Estradiol
225:
224:
220:
217:
214:
211:
208:
206:
205:Estetrol (E4)
203:
202:
198:
195:
192:
189:
186:
184:
181:
180:
176:
173:
170:
167:
164:
162:
159:
158:
154:
151:
148:
145:
142:
140:
137:
136:
132:
129:
126:
123:
120:
117:
116:
109:
101:
96:
90:
85:
83:
80:
77:
74:
68:
60:
55:
53:
50:
49:
45:
38:
33:
31:
26:
24:
19:
18:
916:
910:
890:
883:
858:
854:
848:
823:
819:
813:
786:
780:
755:
751:
745:
712:
708:
698:
673:
669:
663:
630:
626:
620:
569:
557:
512:
183:Estriol (E3)
161:Estrone (E1)
20:
917:Climacteric
564:(i.e., not
495:0.01 ± 0.00
429:0.13 ± 0.04
385:0.01 ± 0.00
275:0.05 ± 0.04
82:Uterotrophy
985:Categories
709:Pediatrics
612:References
566:endogenous
558:Footnotes:
94:levels (%)
991:Estrogens
562:Synthetic
552:levels =
473:0.9 ± 0.3
451:2.8 ± 1.0
363:1.9 ± 0.8
319:1.3 ± 0.2
231:4.2 ± 0.8
209:0.5 ± 0.2
44:estrogens
941:24616324
933:16112947
737:29609115
655:54412821
627:Steroids
590:See also
570:Sources:
501:Inactive
463:<0.5
454:552 ± 42
391:Inactive
369:Inactive
341:180 ± 43
281:Inactive
215:Inactive
190:468 ± 30
168:490 ± 22
146:506 ± 20
52:Estrogen
46:in rats
958:|
875:6310247
840:7190977
535:cytosol
532:uterine
530:of rat
388:103 ± 7
372:110–142
366:130 ± 9
297:45 ± 12
256:285 ± 8
118:Control
972:pages.
968:create
960:mirror
956:create
939:
931:
898:
873:
838:
801:
772:499073
770:
735:
729:724350
727:
690:590186
688:
653:
647:178074
645:
513:Notes:
407:11 ± 4
394:95–100
253:24 ± 7
187:10 ± 4
165:11 ± 8
937:S2CID
733:S2CID
651:S2CID
438:65–92
416:21–50
262:31–61
152:12–19
929:PMID
896:ISBN
871:PMID
836:PMID
799:ISBN
768:PMID
725:PMID
686:PMID
643:PMID
460:7–24
397:120
287:130
196:8–18
155:100
113:(%)
99:SHBG
921:doi
863:doi
828:doi
791:doi
760:doi
756:105
717:doi
678:doi
674:101
635:doi
526:to
520:RBA
476:302
457:+++
441:12
432:338
419:35
410:351
347:+++
322:260
278:101
265:28
193:+++
177:20
171:+++
149:+++
143:100
130:100
124:100
107:RBA
78:(%)
72:(%)
66:RBA
987::
935:.
927:.
869:.
859:19
857:.
834:.
824:51
822:.
797:.
766:.
754:.
731:.
723:.
713:62
711:.
707:.
684:.
672:.
649:.
641:.
631:27
629:.
560:=
550:LH
548:.
522:=
517:ER
507:4
485:?
435:++
413:++
375:8
353:?
331:9
325:++
309:?
243:?
221:1
199:3
133:–
88:LH
58:ER
977:.
970:)
966:(
962:)
954:(
943:.
923::
904:.
877:.
865::
842:.
830::
807:.
793::
774:.
762::
739:.
719::
692:.
680::
657:.
637::
504:?
498:?
482:?
479:+
350:?
344:?
328:?
306:?
303:?
300:?
284:?
259:+
240:?
237:?
234:?
218:?
212:?
174:?
127:–
121:–
36:e
29:t
22:v
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.