312:
289:
186:
211:
3828:
3813:
3798:
318:
217:
31:
2028:
1793:
1240:
gene which always has active copies. For example, in a bimodular configuration most common among
Europeans, the cluster consists of the following genes: STK19-C4A-CYP21A1P-TNXA-STK19B-C4B-CYP21A2-TNXB. As such, TNXA is a duplicated copy of TNXB, but is incomplete, therefore, TNXA a pseudogene that is
1455:
Tenascin-X (TNX) protein was discovered during studies of human steroidogenesis and its disorders, particularly in patients with 21-hydroxylase deficiency, rather than during studies of connective tissue disorders. Researchers sequenced a 2.7 kb cDNA clone that showed similarities to tenascin,
57:
1481:
ENSG00000236221, ENSG00000229353, ENSG00000229341, ENSG00000233323, ENSG00000231608, ENSG00000206258, ENSG00000168477 GRCh38: Ensembl release 89: ENSG00000236236, ENSG00000236221, ENSG00000229353, ENSG00000229341, ENSG00000233323, ENSG00000231608, ENSG00000206258,
2738:
Zweers MC, Schalkwijk J, van
Kuppevelt TH, van Vlijmen-Willems IM, Bergers M, Lethias C, et al. (February 2005). "Transplantation of reconstructed human skin on nude mice: a model system to study expression of human tenascin-X and elastic fiber components".
1456:
leading to the identification of the XB gene. This gene was initially called "Gene X" because its nature and function were unknown at the time. Further research revealed that this gene encodes the
Tenascin-X protein, which belongs to the family of tenascins.
2782:
Voermans NC, Jenniskens GJ, Hamel BC, Schalkwijk J, Guicheney P, van
Engelen BG (September 2007). "Ehlers-Danlos syndrome due to tenascin-X deficiency: muscle weakness and contractures support overlap with collagen VI myopathies".
1555:
Tee MK, Thomson AA, Bristow J, Miller WL (July 1995). "Sequences promoting the transcription of the human XA gene overlapping P450c21A correctly predict the presence of a novel, adrenal-specific, truncated form of tenascin-X".
2032:
1797:
3625:
Vignal C, Bansal AT, Balding DJ, Binks MH, Dickson MC, Montgomery DS, et al. (January 2009). "Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci".
3016:
Egging D, van
Vlijmen-Willems I, van Tongeren T, Schalkwijk J, Peeters A (2007). "Wound healing in tenascin-X deficient mice suggests that tenascin-X is involved in matrix maturation rather than matrix deposition".
3692:
Gudbjartsson DF, Bjornsdottir US, Halapi E, Helgadottir A, Sulem P, Jonsdottir GM, et al. (March 2009). "Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction".
3097:
Kato A, Endo T, Abiko S, Ariga H, Matsumoto K (August 2008). "Induction of truncated form of tenascin-X (XB-S) through dissociation of HDAC1 from SP-1/HDAC1 complex in response to hypoxic conditions".
2695:
Demirdas S, Dulfer E, Robert L, Kempers M, van Beek D, Micha D, et al. (March 2017). "Recognizing the tenascin-X deficient type of Ehlers-Danlos syndrome: a cross-sectional study in 17 patients".
1347:(muscle components), renal glomeruli, blood vessels and skin dermis. TN-X has been proposed to have an important structural and architectural function, especially within the skin. In fact,
2599:
Mao JR, Taylor G, Dean WB, Wagner DR, Afzal V, Lotz JC, et al. (April 2002). "Tenascin-X deficiency mimics Ehlers-Danlos syndrome in mice through alteration of collagen deposition".
2642:
Schalkwijk J, Zweers MC, Steijlen PM, Dean WB, Taylor G, van
Vlijmen IM, et al. (October 2001). "A recessive form of the Ehlers-Danlos syndrome caused by tenascin-X deficiency".
3457:
Gudbjartsson DF, Walters GB, Thorleifsson G, Stefansson H, Halldorsson BV, Zusmanovich P, et al. (May 2008). "Many sequence variants affecting diversity of adult human height".
3827:
3812:
3797:
3496:"High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions"
325:
224:
2944:
Goepel C (2008). "Differential elastin and tenascin immunolabeling in the uterosacral ligaments in postmenopausal women with and without pelvic organ prolapse".
2047:
1812:
1120:
Deficiencies in the TN-X protein due to mutations or not enough of it being produced (haploinsufficiency) can lead to a rare condition called classical-like
3420:
Araújo VC, Furuse C, Cury PR, Altemani A, Alves VA, de Araújo NS (January 2008). "Tenascin and fibronectin expression in carcinoma ex pleomorphic adenoma".
3868:
3745:
3655:
Buysschaert ID, Grulois V, Eloy P, Jorissen M, Rombaux P, Bertrand B, et al. (May 2010). "Genetic evidence for a role of IL33 in nasal polyposis".
787:
147:
768:
3225:"Identification of a significant association of a single nucleotide polymorphism in TNXB with systemic lupus erythematosus in a Japanese population"
2325:
Lethias C, Descollonges Y, Boutillon MM, Garrone R (April 1996). "Flexilin: a new extracellular matrix glycoprotein localized on collagen fibrils".
1132:
TN-X possesses a modular structure composed, from the N- to the C-terminal part by a
Tenascin assembly domain (TAD), a series of 18.5 repeats of
3777:
1537:
1519:
4547:
1117:
The TN-X protein is expressed in many parts of the human body, including the skin, muscles, kidneys, blood vessels, and digestive tract.
311:
4516:
1758:
1741:
3163:
1036:
1029:
288:
3377:"Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966"
1370:(Fibrillar Associated Collagen with Interruption of the Triple helix) including type XII and XIV collagens. It also interacts with
1742:"The tenascin family of ECM glycoproteins: structure, function, and regulation during embryonic development and tissue remodeling"
1401:
1439:(EDS), a rare and hereditary connective tissue disorder in mice and human. This pathology is characterized by skin hyperlaxity,
1232:, but if there are two or more modules within the cluster, there is only one copy of each functional gene rest being non-coding
1506:
1485:
1371:
4526:
3861:
3338:
Endo T, Ariga H, Matsumoto K (January 2009). "Truncated form of tenascin-X, XB-S, interacts with mitotic motor kinesin Eg5".
1502:
210:
185:
4248:
4152:
4127:
1480:
4280:
4209:
4147:
4142:
1124:(EDS). People with EDS may have loose joints and weak tissues because their bodies don't make enough collagen properly.
127:
1436:
4198:
4157:
4044:
4039:
4034:
4028:
3947:
2066:"Tenascin-X haploinsufficiency associated with Ehlers-Danlos syndrome in patients with congenital adrenal hyperplasia"
1359:
1137:
1121:
1404:
coupled with immuno-labelling confirms the very close location of TN-X with collagen fibbers in dermis, tendons and
324:
223:
4236:
4172:
4115:
4087:
4077:
4007:
3940:
1980:"Molecular basis and genetic testing strategies for diagnosing 21-hydroxylase deficiency, including CAH-X syndrome"
1411:
In addition to this architectural function, TN-X also demonstrated counter-adhesive properties, at least for human
3178:
Fellay J, Ge D, Shianna KV, Colombo S, Ledergerber B, Cirulli ET, et al. (December 2009). McCarthy MI (ed.).
2882:"Transcript encoded on the opposite strand of the human steroid 21-hydroxylase/complement component C4 gene locus"
4225:
3960:
3922:
3854:
3770:
317:
216:
3494:
Barcellos LF, May SL, Ramsay PP, Quach HL, Lane JA, Nititham J, et al. (October 2009). Roopenian DC (ed.).
3375:
Sovio U, Bennett AJ, Millwood IY, Molitor J, O'Reilly PF, Timpson NJ, et al. (March 2009). Gibson G (ed.).
862:
135:
1882:"Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes"
54:
1199:
843:
839:
835:
825:
821:
817:
813:
809:
3056:"Analysis of obstetric complications and uterine connective tissue in tenascin-X-deficient humans and mice"
2503:"Ehlers-Danlos Syndrome Caused by Biallelic TNXB Variants in Patients with Congenital Adrenal Hyperplasia"
1316:
1209:
3737:
4294:
1257:
3541:"Association of MHC SNP genotype with susceptibility to type 1 diabetes: a modified survival approach"
1931:"Intraspecific evolution of human RCCX copy number variation traced by haplotypes of the CYP21A2 gene"
3889:
3763:
3260:"Several loci in the HLA class III region are associated with T1D risk after adjusting for DRB1-DQB1"
2893:
2362:"Cell adhesion to tenascin-X mapping of cell adhesion sites and identification of integrin receptors"
2281:
2175:
199:
114:
4121:
3054:
Egging DF, van
Vlijmen-Willems I, Choi J, Peeters AC, van Rens D, Veit G, et al. (June 2008).
2454:"Broadening the Spectrum of Ehlers Danlos Syndrome in Patients With Congenital Adrenal Hyperplasia"
1440:
1229:
993:
938:
2501:
Chen W, Perritt AF, Morissette R, Dreiling JL, Bohn MF, Mallappa A, et al. (September 2016).
4552:
4460:
4271:
3718:
3680:
3482:
3445:
3363:
3326:
3155:
3042:
2808:
2764:
2720:
2677:
2624:
2581:
2307:
2201:
1911:
1771:
1432:
159:
989:
985:
959:
934:
930:
3584:"Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease"
3582:
Chapuis J, Hot D, Hansmannel F, Kerdraon O, Ferreira S, Hubans C, et al. (November 2009).
118:, EDS3, HXBL, TENX, TN-X, TNX, TNXB1, TNXB2, TNXBS, VUR8, XB, XBS, tenascin XB, EDSCLL, EDSCLL1
4465:
4275:
4066:
3710:
3672:
3643:
3613:
3570:
3527:
3474:
3437:
3408:
3355:
3318:
3289:
3246:
3211:
3147:
3114:
3085:
3034:
3004:
2961:
2921:
2862:
2800:
2756:
2712:
2669:
2616:
2573:
2532:
2483:
2452:
Morissette R, Chen W, Perritt AF, Dreiling JL, Arai AE, Sachdev V, et al. (August 2015).
2434:
2383:
2342:
2299:
2250:
2193:
2144:
2095:
2009:
1960:
1903:
1862:
1763:
1722:
1673:
1622:
1573:
1336:
107:
47:
4390:
4385:
4346:
4341:
4336:
4331:
4326:
4071:
3935:
3702:
3664:
3635:
3603:
3595:
3560:
3552:
3517:
3507:
3466:
3429:
3398:
3388:
3347:
3310:
3279:
3271:
3236:
3201:
3191:
3139:
3106:
3075:
3067:
3026:
2994:
2986:
2953:
2911:
2901:
2852:
2842:
2792:
2748:
2704:
2659:
2651:
2608:
2563:
2550:
Malfait F, Francomano C, Byers P, Belmont J, Berglund B, Black J, et al. (March 2017).
2522:
2514:
2473:
2465:
2424:
2414:
2403:"Tenascin-X induces cell detachment through p38 mitogen-activated protein kinase activation"
2373:
2334:
2289:
2240:
2232:
2183:
2134:
2126:
2085:
2077:
1999:
1991:
1950:
1942:
1893:
1852:
1842:
1753:
1712:
1704:
1663:
1653:
1612:
1604:
1565:
1405:
1386:
404:
335:
279:
234:
3127:
2219:
Alcaraz LB, Exposito JY, Chuvin N, Pommier RM, Cluzel C, Martel S, et al. (May 2014).
2064:
Merke DP, Chen W, Morissette R, Xu Z, Van Ryzin C, Sachdev V, et al. (February 2013).
4511:
4368:
4363:
4358:
3954:
3916:
1393:
1363:
1355:
1133:
379:
155:
1228:). In a monomodular structure of the RCCX cluster, all of the genes are functional, i.e.
2973:
Yuan Y, Nymoen DA, Stavnes HT, Rosnes AK, Bjørang O, Wu C, et al. (November 2009).
2897:
2285:
2179:
2004:
1979:
1668:
1641:
1161:) region on chromosome 6. The structure of this gene is unusual in that it overlaps the
3998:
3608:
3583:
3565:
3540:
3522:
3495:
3403:
3376:
3284:
3259:
3206:
3179:
3080:
3055:
2999:
2974:
2857:
2830:
2527:
2502:
2478:
2453:
2245:
2220:
2139:
2114:
2090:
2065:
1955:
1930:
1857:
1830:
1717:
1692:
1617:
1592:
1367:
1217:
1166:
2916:
2881:
2338:
2294:
2269:
702:
697:
692:
687:
682:
677:
661:
656:
651:
646:
641:
636:
631:
615:
610:
605:
600:
595:
4541:
4299:
3881:
3749:
3668:
3556:
3275:
2724:
2378:
2361:
2221:"Tenascin-X promotes epithelial-to-mesenchymal transition by activating latent TGF-β"
1300:
1245:
1158:
582:
3836:: Solution structure of the 31st fibronectin type III domain of the human tenascin X
3821:: Solution structure of the 31st fibronectin type III domain of the human tenascin X
3806:: The solution structure of the 33rd fibronectin type III domain of human Tenascin-X
3684:
3449:
3367:
3330:
3223:
Kamatani Y, Matsuda K, Ohishi T, Ohtsubo S, Yamazaki K, Iida A, et al. (2008).
3159:
3046:
2681:
2628:
2311:
2205:
1929:
Bánlaki Z, Szabó JA, Szilágyi Á, Patócs A, Prohászka Z, Füst G, et al. (2013).
1915:
1775:
139:
4423:
3722:
3486:
2812:
2768:
2585:
1412:
1389:
1304:
1100:
397:
176:
2188:
2163:
3512:
3433:
3393:
3196:
2990:
2957:
2130:
1608:
163:
4501:
4430:
4166:
4111:
3110:
1542:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1524:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1420:
1296:
1107:
family, that is expressed in connective tissues. In humans it is encoded by the
1658:
1335:, and colon. In this wide variety of organs, TN-X is mainly located within the
1198:
cluster, which consists of a series of modules with genes close to each other:
480:
4132:
3351:
3241:
3224:
3071:
3030:
2847:
2752:
1847:
1416:
1344:
1233:
296:
193:
143:
3301:
Yu CY (1998). "Molecular genetics of the human MHC complement gene cluster".
1995:
2906:
1340:
732:
540:
418:
363:
350:
262:
249:
151:
3738:
GeneReviews/NCBI/NIH/UW entry on Ehlers-Danlos Syndrome, Hypermobility Type
3714:
3676:
3647:
3617:
3574:
3531:
3478:
3441:
3412:
3359:
3322:
3293:
3250:
3215:
3151:
3118:
3089:
3038:
3008:
2965:
2866:
2804:
2760:
2716:
2673:
2620:
2577:
2536:
2487:
2438:
2387:
2303:
2254:
2197:
2148:
2099:
2013:
1964:
1907:
1866:
1767:
1726:
1677:
1626:
1569:
3846:
3132:
American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
2925:
2556:
American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
2346:
2236:
2113:
Valcourt U, Alcaraz LB, Exposito JY, Lethias C, Bartholin L (2015-01-02).
1759:
10.1002/(SICI)1097-0177(200006)218:2<235::AID-DVDY2>3.0.CO;2-G
1577:
1076:
1071:
30:
4284:
4263:
3900:
3143:
2796:
2655:
2568:
2551:
2469:
2081:
2037:
1946:
1898:
1881:
1802:
1378:
1375:
1352:
1320:
1308:
1280:
1104:
1060:
888:
2419:
2402:
4506:
4497:
4445:
4418:
4313:
4289:
4253:
4241:
4059:
4054:
4049:
3977:
3877:
3599:
2664:
2518:
1642:"Tenascin-X as a causal gene for classical-like Ehlers-Danlos syndrome"
1444:
1382:
1328:
1324:
874:
799:
3639:
3314:
2708:
2552:"The 2017 international classification of the Ehlers-Danlos syndromes"
2429:
2162:
Lethias C, Carisey A, Comte J, Cluzel C, Exposito JY (November 2006).
1880:
Bánlaki Z, Doleschall M, Rajczy K, Fust G, Szilágyi A (October 2012).
1708:
1431:
Homozygous mutations, heterozygous compound (bi-allelic) mutations or
1351:
experiments demonstrate that TN-X physically interacts with fibrillar
84:
80:
76:
4450:
4214:
4187:
4182:
4177:
4102:
4097:
4092:
4082:
4017:
4012:
3970:
3965:
3927:
2042:
1807:
1292:
1284:
1162:
1044:
754:
1693:"Tenascin-X, Congenital Adrenal Hyperplasia, and the CAH-X Syndrome"
1591:
Valcourt U, Alcaraz LB, Exposito JY, Lethias C, Bartholin L (2015).
3706:
3470:
2975:"Tenascin-X is a novel diagnostic marker of malignant mesothelioma"
4475:
4470:
4440:
4435:
4413:
4395:
4373:
3982:
2612:
2164:"A model of tenascin-X integration within the collagenous network"
1339:
such as peritendineum (external structural component of tendons),
1332:
1312:
1204:
1831:"Genes and Pseudogenes: Complexity of the RCCX Locus and Disease"
717:
713:
4455:
2038:"TNXA tenascin XA (pseudogene) [ Homo sapiens (human) ]"
1447:
fragmentation and reduced collagen density, especially in skin.
1288:
1276:
1195:
1178:
1111:
131:
3850:
3759:
3128:"Tenascin-X, collagen, elastin, and the Ehlers-Danlos syndrome"
2360:
Elefteriou F, Exposito JY, Garrone R, Lethias C (August 1999).
1248:
locus duplication during evolution. Strong 3' homology between
3755:
2268:
Elefteriou F, Exposito JY, Garrone R, Lethias C (April 2001).
1140:(FNIII) module, and a fibrinogen (FBG)-like globular domain.
3180:"Common genetic variation and the control of HIV-1 in humans"
2880:
Morel Y, Bristow J, Gitelman SE, Miller WL (September 1989).
3126:
Bristow J, Carey W, Egging D, Schalkwijk J (November 2005).
1275:
TN-X is constitutively expressed in adult tissues such as
3539:
McKinnon E, Morahan G, Nolan D, James I (February 2009).
1260:
between the two loci, thus leading to the apparition of
1157:
gene localizes to the major histocompatibility complex (
387:
3422:
Applied Immunohistochemistry & Molecular Morphology
2401:
Fujie S, Maita H, Ariga H, Matsumoto K (October 2009).
1829:
Carrozza C, Foca L, De Paolis E, Concolino P (2021).
552:
2458:
The Journal of Clinical Endocrinology and Metabolism
2070:
The Journal of Clinical Endocrinology and Metabolism
1315:. It is also found in different compartments of the
4490:
4406:
4312:
4262:
3991:
3908:
3899:
3888:
1787:
1785:
1007:
978:
952:
923:
1498:
1496:
1494:
1476:
1474:
1472:
1244:The presence of the pseudogeneis a consequence of
334:
233:
1194:Both TNXA and TNXB genes are located within the
2824:
2822:
2115:"Tenascin-X: beyond the architectural function"
1824:
1822:
1593:"Tenascin-X: beyond the architectural function"
1443:and global tissue weakness as a consequence of
16:Protein-coding gene in the species Homo sapiens
1503:GRCm38: Ensembl release 89: ENSMUSG00000033327
3862:
3771:
2048:National Center for Biotechnology Information
1978:Kim JH, Kim GH, Yoo HW, Choi JH (June 2023).
1813:National Center for Biotechnology Information
1803:"TNXB tenascin XB [ Homo sapiens (human)"
8:
2785:American Journal of Medical Genetics. Part A
1241:transcribed but does not encode a protein.
1169:genes at its 5' and 3' ends, respectively.
611:extracellular matrix structural constituent
3905:
3896:
3869:
3855:
3847:
3778:
3764:
3756:
3746:United States National Library of Medicine
2979:The American Journal of Surgical Pathology
804:
728:
578:
375:
274:
171:
65:
3607:
3564:
3521:
3511:
3402:
3392:
3283:
3240:
3205:
3195:
3079:
2998:
2915:
2905:
2856:
2846:
2831:"Tenascin-X-Discovery and Early Research"
2663:
2567:
2526:
2477:
2428:
2418:
2377:
2293:
2244:
2187:
2138:
2089:
2003:
1954:
1897:
1856:
1846:
1757:
1716:
1667:
1657:
1616:
3744:This article incorporates text from the
3303:Experimental and Clinical Immunogenetics
2407:Biological & Pharmaceutical Bulletin
1134:epidermal growth factor (EGF)-like motif
662:collagen-containing extracellular matrix
3793:
1640:Okuda-Ashitaka E, Matsumoto KI (2023).
1468:
3258:Valdes AM, Thomson G (February 2009).
1392:that plays a crucial role in collagen
20:
2059:
2057:
339:
300:
295:
238:
197:
192:
7:
4517:Cartilage oligomeric matrix protein
3340:Molecular and Cellular Biochemistry
2644:The New England Journal of Medicine
1187:gene has an associated pseudogene,
527:medial head of gastrocnemius muscle
3545:Diabetes, Obesity & Metabolism
3264:Diabetes, Obesity & Metabolism
2270:"Binding of tenascin-X to decorin"
1372:Transforming Growth Factor (TGF)-β
1004:
975:
949:
920:
898:
879:
853:
778:
759:
637:intracellular anatomical structure
557:
475:
413:
392:
14:
688:extracellular matrix organization
3826:
3811:
3796:
3669:10.1111/j.1398-9995.2009.02227.x
3557:10.1111/j.1463-1326.2008.01009.x
3276:10.1111/j.1463-1326.2008.01002.x
2379:10.1046/j.1432-1327.1999.00563.x
2366:European Journal of Biochemistry
2031: This article incorporates
2026:
1796: This article incorporates
1791:
1740:Jones FS, Jones PL (June 2000).
1415:cells (MG-63), murine embryonic
1402:transmission electron microscopy
515:extensor digitorum longus muscle
323:
316:
310:
287:
222:
215:
209:
184:
29:
3166:from the original on 2022-06-10
703:actin cytoskeleton organization
541:More reference expression data
1:
2339:10.1016/S0945-053X(96)90122-5
2295:10.1016/S0014-5793(01)02361-4
2189:10.1016/j.febslet.2006.10.037
2119:Cell Adhesion & Migration
2043:Reference Sequence collection
1808:Reference Sequence collection
1435:in TN-X cause classical-like
507:tunica media of zone of aorta
308:
207:
4281:Cartilage associated protein
3513:10.1371/journal.pgen.1000696
3434:10.1097/PAI.0b013e31802eff1c
3394:10.1371/journal.pgen.1000409
3197:10.1371/journal.pgen.1000791
2991:10.1097/PAS.0b013e3181b6bde3
2958:10.1016/j.acthis.2007.10.014
2131:10.4161/19336918.2014.994893
1984:Ann Pediatr Endocrinol Metab
1691:Miller WL, Merke DP (2018).
1609:10.4161/19336918.2014.994893
678:collagen fibril organization
4548:Genes on human chromosome 6
3111:10.1016/j.yexcr.2008.05.019
2225:The Journal of Cell Biology
1835:Front Endocrinol (Lausanne)
4569:
3099:Experimental Cell Research
3019:Connective Tissue Research
1659:10.3389/fgene.2023.1107787
1236:with the exception of the
1176:
683:collagen metabolic process
3791:
3352:10.1007/s11010-008-9898-y
3242:10.1007/s10038-007-0219-1
3229:Journal of Human Genetics
3072:10.1007/s00441-008-0591-y
3031:10.1080/03008200601166160
2848:10.3389/fimmu.2020.612497
2753:10.1007/s00441-004-1011-6
1848:10.3389/fendo.2021.709758
1538:"Mouse PubMed Reference:"
1520:"Human PubMed Reference:"
1419:(MRC-5) as well as human
1097:hexabrachion-like protein
1075:
1070:
1066:
1059:
1043:
1024:
1011:
982:
971:
956:
927:
916:
905:
901:
886:
882:
873:
860:
856:
833:
807:
798:
785:
781:
766:
762:
753:
738:
731:
727:
711:
642:fibrillar collagen trimer
581:
577:
565:
560:
551:
538:
487:
478:
425:
416:
386:
378:
374:
357:
344:
307:
286:
277:
273:
256:
243:
206:
183:
174:
170:
125:
122:
112:
105:
100:
73:
68:
51:
46:
41:
37:
28:
23:
3628:Arthritis and Rheumatism
3060:Cell and Tissue Research
2886:Proc Natl Acad Sci U S A
2741:Cell and Tissue Research
1996:10.6065/apem.2346108.054
1037:Chr 17: 34.88 – 34.94 Mb
2907:10.1073/pnas.86.17.6582
1200:serine/threonine kinase
1030:Chr 6: 32.04 – 32.12 Mb
616:collagen fibril binding
2033:public domain material
1798:public domain material
1746:Developmental Dynamics
1570:10.1006/geno.1995.1128
1437:Ehlers-Danlos syndrome
1218:steroid 21-hydroxylase
1149:TNXB (functional gene)
1122:Ehlers-Danlos syndrome
1091:(TN-X), also known as
698:elastic fiber assembly
341:17 B1|17 18.24 cM
52:Human UniProt search:
4295:Procollagen peptidase
2237:10.1083/jcb.201308031
1427:Clinical significance
1258:genetic recombination
647:extracellular exosome
302:Chromosome 17 (mouse)
3588:Molecular Psychiatry
3144:10.1002/ajmg.c.30071
2797:10.1002/ajmg.a.31899
2656:10.1056/NEJMoa002939
2569:10.1002/ajmg.c.31552
2470:10.1210/jc.2015-2232
2082:10.1210/jc.2012-3148
1899:10.1038/gene.2012.29
1138:Fibronectin type III
657:extracellular region
632:extracellular matrix
523:skin of external ear
433:right adrenal cortex
200:Chromosome 6 (human)
69:List of PDB id codes
42:Available structures
3551:(Suppl 1): 92–100.
2898:1989PNAS...86.6582M
2420:10.1248/bpb.32.1795
2286:2001FEBSL.495...44E
2180:2006FEBSL.580.6281L
1441:joint hypermobility
1224:), and tenascin-X (
1136:, a high number of
652:extracellular space
441:left adrenal cortex
4461:Matrix gla protein
4272:Prolyl hydroxylase
3748:, which is in the
3600:10.1038/mp.2009.10
3270:(Suppl 1): 46–52.
2829:Miller WL (2020).
2519:10.1002/humu.23028
2464:(8): E1143–E1152.
1947:10.1093/gbe/evs121
1433:haploinsufficiency
1385:, a small 100 kDa
1103:, a member of the
863:ENSMUSG00000033327
671:Biological process
625:Cellular component
589:Molecular function
499:extraocular muscle
437:left adrenal gland
4535:
4534:
4486:
4485:
4308:
4307:
4276:Lysyl hydroxylase
4067:basement membrane
3844:
3843:
3640:10.1002/art.24138
3594:(11): 1004–1016.
3315:10.1159/000019075
3105:(14): 2661–2673.
2985:(11): 1673–1682.
2946:Acta Histochemica
2791:(18): 2215–2219.
2709:10.1111/cge.12853
2697:Clinical Genetics
2650:(16): 1167–1175.
2413:(10): 1795–1799.
2174:(26): 6281–6285.
1709:10.1159/000481911
1697:Horm Res Paediatr
1423:cells (ECV-304).
1337:connective tissue
1173:TNXA (pseudogene)
1086:
1085:
1082:
1081:
1055:
1054:
1020:
1019:
1001:
1000:
967:
966:
946:
945:
912:
911:
895:
894:
869:
868:
850:
849:
794:
793:
775:
774:
723:
722:
573:
572:
569:
568:
547:
546:
534:
533:
519:lactiferous gland
472:
471:
370:
369:
269:
268:
96:
95:
92:
91:
4560:
3906:
3897:
3871:
3864:
3857:
3848:
3830:
3815:
3800:
3780:
3773:
3766:
3757:
3726:
3688:
3651:
3621:
3611:
3578:
3568:
3535:
3525:
3515:
3506:(10): e1000696.
3490:
3453:
3416:
3406:
3396:
3371:
3334:
3297:
3287:
3254:
3244:
3219:
3209:
3199:
3190:(12): e1000791.
3174:
3172:
3171:
3122:
3093:
3083:
3050:
3012:
3002:
2969:
2930:
2929:
2919:
2909:
2877:
2871:
2870:
2860:
2850:
2826:
2817:
2816:
2779:
2773:
2772:
2735:
2729:
2728:
2692:
2686:
2685:
2667:
2639:
2633:
2632:
2596:
2590:
2589:
2571:
2547:
2541:
2540:
2530:
2498:
2492:
2491:
2481:
2449:
2443:
2442:
2432:
2422:
2398:
2392:
2391:
2381:
2357:
2351:
2350:
2322:
2316:
2315:
2297:
2265:
2259:
2258:
2248:
2216:
2210:
2209:
2191:
2159:
2153:
2152:
2142:
2125:(1–2): 154–165.
2110:
2104:
2103:
2093:
2076:(2): E379–E387.
2061:
2052:
2051:
2030:
2029:
2024:
2018:
2017:
2007:
1975:
1969:
1968:
1958:
1935:Genome Biol Evol
1926:
1920:
1919:
1901:
1877:
1871:
1870:
1860:
1850:
1826:
1817:
1816:
1795:
1794:
1789:
1780:
1779:
1761:
1737:
1731:
1730:
1720:
1688:
1682:
1681:
1671:
1661:
1637:
1631:
1630:
1620:
1588:
1582:
1581:
1552:
1546:
1545:
1534:
1528:
1527:
1516:
1510:
1500:
1489:
1478:
1406:kidney glomeruli
1387:dermatan sulfate
1068:
1067:
1039:
1032:
1015:
1005:
996:
976:
972:RefSeq (protein)
962:
950:
941:
921:
899:
880:
854:
829:
805:
779:
760:
729:
596:integrin binding
579:
558:
543:
511:plantaris muscle
483:
481:Top expressed in
476:
421:
419:Top expressed in
414:
393:
376:
366:
353:
342:
327:
320:
314:
303:
291:
275:
265:
252:
241:
226:
219:
213:
202:
188:
172:
166:
164:TNXB - orthologs
117:
110:
87:
66:
60:
39:
38:
33:
21:
4568:
4567:
4563:
4562:
4561:
4559:
4558:
4557:
4538:
4537:
4536:
4531:
4482:
4402:
4304:
4258:
4141:transmembrane:
3987:
3891:
3884:
3875:
3845:
3840:
3837:
3831:
3822:
3816:
3807:
3801:
3787:
3784:
3734:
3729:
3695:Nature Genetics
3691:
3654:
3624:
3581:
3538:
3493:
3459:Nature Genetics
3456:
3419:
3387:(3): e1000409.
3374:
3337:
3300:
3257:
3222:
3177:
3169:
3167:
3125:
3096:
3053:
3015:
2972:
2943:
2939:
2937:Further reading
2934:
2933:
2879:
2878:
2874:
2828:
2827:
2820:
2781:
2780:
2776:
2737:
2736:
2732:
2694:
2693:
2689:
2641:
2640:
2636:
2601:Nature Genetics
2598:
2597:
2593:
2549:
2548:
2544:
2500:
2499:
2495:
2451:
2450:
2446:
2400:
2399:
2395:
2359:
2358:
2354:
2324:
2323:
2319:
2267:
2266:
2262:
2218:
2217:
2213:
2161:
2160:
2156:
2112:
2111:
2107:
2063:
2062:
2055:
2036:
2027:
2025:
2021:
1977:
1976:
1972:
1928:
1927:
1923:
1879:
1878:
1874:
1828:
1827:
1820:
1801:
1792:
1790:
1783:
1739:
1738:
1734:
1690:
1689:
1685:
1639:
1638:
1634:
1603:(1–2): 154–65.
1590:
1589:
1585:
1554:
1553:
1549:
1536:
1535:
1531:
1518:
1517:
1513:
1501:
1492:
1482:ENSG00000168477
1479:
1470:
1465:
1459:
1453:
1429:
1394:fibrillogenesis
1374:which is a pro-
1317:digestive tract
1273:
1181:
1175:
1151:
1146:
1130:
1077:View/Edit Mouse
1072:View/Edit Human
1035:
1028:
1025:Location (UCSC)
1013:
992:
988:
984:
958:
937:
933:
929:
844:ENSG00000168477
842:
840:ENSG00000206258
838:
836:ENSG00000231608
828:
826:ENSG00000233323
824:
822:ENSG00000229341
820:
818:ENSG00000229353
816:
814:ENSG00000236221
812:
810:ENSG00000236236
808:
707:
666:
620:
606:heparin binding
601:protein binding
539:
530:
525:
521:
517:
513:
509:
505:
501:
497:
493:
479:
468:
463:
459:
455:
451:
447:
443:
439:
435:
431:
417:
361:
348:
340:
330:
329:
328:
321:
301:
278:Gene location (
260:
247:
239:
229:
228:
227:
220:
198:
175:Gene location (
126:
113:
106:
75:
53:
17:
12:
11:
5:
4566:
4564:
4556:
4555:
4550:
4540:
4539:
4533:
4532:
4530:
4529:
4524:
4520:
4519:
4514:
4509:
4504:
4494:
4492:
4488:
4487:
4484:
4483:
4481:
4480:
4479:
4478:
4473:
4463:
4458:
4453:
4448:
4443:
4438:
4433:
4428:
4427:
4426:
4416:
4410:
4408:
4404:
4403:
4401:
4400:
4399:
4398:
4393:
4388:
4378:
4377:
4376:
4371:
4366:
4361:
4351:
4350:
4349:
4344:
4339:
4334:
4329:
4318:
4316:
4310:
4309:
4306:
4305:
4303:
4302:
4297:
4292:
4287:
4278:
4268:
4266:
4260:
4259:
4257:
4256:
4251:
4246:
4245:
4244:
4239:
4229:
4219:
4218:
4217:
4212:
4202:
4192:
4191:
4190:
4185:
4180:
4175:
4161:
4160:
4155:
4150:
4145:
4138:
4137:
4136:
4135:
4130:
4118:
4108:
4107:
4106:
4105:
4100:
4095:
4090:
4085:
4080:
4063:
4062:
4057:
4052:
4047:
4042:
4037:
4032:
4022:
4021:
4020:
4015:
4010:
3995:
3993:
3989:
3988:
3986:
3985:
3980:
3975:
3974:
3973:
3968:
3963:
3951:
3944:
3932:
3931:
3930:
3925:
3912:
3910:
3909:Fibril forming
3903:
3894:
3890:Extracellular
3886:
3885:
3882:scleroproteins
3876:
3874:
3873:
3866:
3859:
3851:
3842:
3841:
3839:
3838:
3832:
3825:
3823:
3817:
3810:
3808:
3802:
3795:
3792:
3789:
3788:
3785:
3783:
3782:
3775:
3768:
3760:
3741:
3740:
3733:
3732:External links
3730:
3728:
3727:
3707:10.1038/ng.323
3701:(3): 342–347.
3689:
3663:(5): 616–622.
3652:
3622:
3579:
3536:
3491:
3471:10.1038/ng.122
3465:(5): 609–615.
3454:
3417:
3372:
3346:(1–2): 53–66.
3335:
3309:(4): 213–230.
3298:
3255:
3220:
3175:
3123:
3094:
3066:(3): 523–532.
3051:
3013:
2970:
2952:(3): 204–209.
2940:
2938:
2935:
2932:
2931:
2892:(17): 6582–6.
2872:
2818:
2774:
2747:(2): 279–287.
2730:
2703:(3): 411–425.
2687:
2634:
2607:(4): 421–425.
2591:
2542:
2513:(9): 893–897.
2507:Human Mutation
2493:
2444:
2393:
2372:(3): 840–848.
2352:
2327:Matrix Biology
2317:
2280:(1–2): 44–47.
2260:
2231:(3): 409–428.
2211:
2154:
2105:
2053:
2019:
1970:
1921:
1892:(7): 530–535.
1872:
1818:
1781:
1752:(2): 235–259.
1732:
1703:(5): 352–361.
1683:
1632:
1583:
1564:(2): 171–178.
1547:
1529:
1511:
1490:
1467:
1466:
1464:
1461:
1452:
1449:
1428:
1425:
1301:adrenal glands
1299:, mammary and
1272:
1269:
1230:protein-coding
1174:
1171:
1150:
1147:
1145:
1142:
1129:
1126:
1099:, is a 450kDa
1084:
1083:
1080:
1079:
1074:
1064:
1063:
1057:
1056:
1053:
1052:
1050:
1048:
1041:
1040:
1033:
1026:
1022:
1021:
1018:
1017:
1009:
1008:
1002:
999:
998:
980:
979:
973:
969:
968:
965:
964:
954:
953:
947:
944:
943:
925:
924:
918:
914:
913:
910:
909:
903:
902:
896:
893:
892:
884:
883:
877:
871:
870:
867:
866:
858:
857:
851:
848:
847:
831:
830:
802:
796:
795:
792:
791:
783:
782:
776:
773:
772:
764:
763:
757:
751:
750:
745:
740:
736:
735:
725:
724:
721:
720:
709:
708:
706:
705:
700:
695:
690:
685:
680:
674:
672:
668:
667:
665:
664:
659:
654:
649:
644:
639:
634:
628:
626:
622:
621:
619:
618:
613:
608:
603:
598:
592:
590:
586:
585:
575:
574:
571:
570:
567:
566:
563:
562:
555:
549:
548:
545:
544:
536:
535:
532:
531:
529:
528:
524:
520:
516:
512:
508:
504:
500:
496:
492:
488:
485:
484:
473:
470:
469:
467:
466:
462:
458:
454:
453:body of uterus
450:
446:
445:gastric mucosa
442:
438:
434:
430:
426:
423:
422:
410:
409:
401:
390:
384:
383:
380:RNA expression
372:
371:
368:
367:
359:
355:
354:
346:
343:
338:
332:
331:
322:
315:
309:
305:
304:
299:
293:
292:
284:
283:
271:
270:
267:
266:
258:
254:
253:
245:
242:
240:6p21.33-p21.32
237:
231:
230:
221:
214:
208:
204:
203:
196:
190:
189:
181:
180:
168:
167:
124:
120:
119:
111:
103:
102:
98:
97:
94:
93:
90:
89:
71:
70:
62:
61:
50:
44:
43:
35:
34:
26:
25:
15:
13:
10:
9:
6:
4:
3:
2:
4565:
4554:
4551:
4549:
4546:
4545:
4543:
4528:
4525:
4522:
4521:
4518:
4515:
4513:
4510:
4508:
4505:
4503:
4499:
4496:
4495:
4493:
4489:
4477:
4474:
4472:
4469:
4468:
4467:
4464:
4462:
4459:
4457:
4454:
4452:
4449:
4447:
4444:
4442:
4439:
4437:
4434:
4432:
4429:
4425:
4422:
4421:
4420:
4417:
4415:
4412:
4411:
4409:
4405:
4397:
4394:
4392:
4389:
4387:
4384:
4383:
4382:
4379:
4375:
4372:
4370:
4367:
4365:
4362:
4360:
4357:
4356:
4355:
4352:
4348:
4345:
4343:
4340:
4338:
4335:
4333:
4330:
4328:
4325:
4324:
4323:
4320:
4319:
4317:
4315:
4311:
4301:
4300:Lysyl oxidase
4298:
4296:
4293:
4291:
4288:
4286:
4282:
4279:
4277:
4273:
4270:
4269:
4267:
4265:
4261:
4255:
4252:
4250:
4247:
4243:
4240:
4238:
4235:
4234:
4233:
4230:
4227:
4223:
4220:
4216:
4213:
4211:
4208:
4207:
4206:
4203:
4200:
4196:
4193:
4189:
4186:
4184:
4181:
4179:
4176:
4174:
4171:
4170:
4169:
4168:
4163:
4162:
4159:
4156:
4154:
4151:
4149:
4146:
4144:
4140:
4139:
4134:
4131:
4129:
4126:
4125:
4124:
4123:
4119:
4117:
4113:
4110:
4109:
4104:
4101:
4099:
4096:
4094:
4091:
4089:
4086:
4084:
4081:
4079:
4076:
4075:
4074:
4073:
4068:
4065:
4064:
4061:
4058:
4056:
4053:
4051:
4048:
4046:
4043:
4041:
4038:
4036:
4033:
4030:
4026:
4023:
4019:
4016:
4014:
4011:
4009:
4006:
4005:
4004:
4000:
3997:
3996:
3994:
3990:
3984:
3981:
3979:
3976:
3972:
3969:
3967:
3964:
3962:
3959:
3958:
3957:
3956:
3952:
3950:
3949:
3945:
3942:
3938:
3937:
3933:
3929:
3926:
3924:
3921:
3920:
3919:
3918:
3914:
3913:
3911:
3907:
3904:
3902:
3898:
3895:
3893:
3887:
3883:
3879:
3872:
3867:
3865:
3860:
3858:
3853:
3852:
3849:
3835:
3829:
3824:
3820:
3814:
3809:
3805:
3799:
3794:
3790:
3781:
3776:
3774:
3769:
3767:
3762:
3761:
3758:
3754:
3753:
3751:
3750:public domain
3747:
3739:
3736:
3735:
3731:
3724:
3720:
3716:
3712:
3708:
3704:
3700:
3696:
3690:
3686:
3682:
3678:
3674:
3670:
3666:
3662:
3658:
3653:
3649:
3645:
3641:
3637:
3633:
3629:
3623:
3619:
3615:
3610:
3605:
3601:
3597:
3593:
3589:
3585:
3580:
3576:
3572:
3567:
3562:
3558:
3554:
3550:
3546:
3542:
3537:
3533:
3529:
3524:
3519:
3514:
3509:
3505:
3501:
3500:PLOS Genetics
3497:
3492:
3488:
3484:
3480:
3476:
3472:
3468:
3464:
3460:
3455:
3451:
3447:
3443:
3439:
3435:
3431:
3427:
3423:
3418:
3414:
3410:
3405:
3400:
3395:
3390:
3386:
3382:
3381:PLOS Genetics
3378:
3373:
3369:
3365:
3361:
3357:
3353:
3349:
3345:
3341:
3336:
3332:
3328:
3324:
3320:
3316:
3312:
3308:
3304:
3299:
3295:
3291:
3286:
3281:
3277:
3273:
3269:
3265:
3261:
3256:
3252:
3248:
3243:
3238:
3234:
3230:
3226:
3221:
3217:
3213:
3208:
3203:
3198:
3193:
3189:
3185:
3184:PLOS Genetics
3181:
3176:
3165:
3161:
3157:
3153:
3149:
3145:
3141:
3137:
3133:
3129:
3124:
3120:
3116:
3112:
3108:
3104:
3100:
3095:
3091:
3087:
3082:
3077:
3073:
3069:
3065:
3061:
3057:
3052:
3048:
3044:
3040:
3036:
3032:
3028:
3024:
3020:
3014:
3010:
3006:
3001:
2996:
2992:
2988:
2984:
2980:
2976:
2971:
2967:
2963:
2959:
2955:
2951:
2947:
2942:
2941:
2936:
2927:
2923:
2918:
2913:
2908:
2903:
2899:
2895:
2891:
2887:
2883:
2876:
2873:
2868:
2864:
2859:
2854:
2849:
2844:
2840:
2836:
2835:Front Immunol
2832:
2825:
2823:
2819:
2814:
2810:
2806:
2802:
2798:
2794:
2790:
2786:
2778:
2775:
2770:
2766:
2762:
2758:
2754:
2750:
2746:
2742:
2734:
2731:
2726:
2722:
2718:
2714:
2710:
2706:
2702:
2698:
2691:
2688:
2683:
2679:
2675:
2671:
2666:
2661:
2657:
2653:
2649:
2645:
2638:
2635:
2630:
2626:
2622:
2618:
2614:
2613:10.1038/ng850
2610:
2606:
2602:
2595:
2592:
2587:
2583:
2579:
2575:
2570:
2565:
2561:
2557:
2553:
2546:
2543:
2538:
2534:
2529:
2524:
2520:
2516:
2512:
2508:
2504:
2497:
2494:
2489:
2485:
2480:
2475:
2471:
2467:
2463:
2459:
2455:
2448:
2445:
2440:
2436:
2431:
2426:
2421:
2416:
2412:
2408:
2404:
2397:
2394:
2389:
2385:
2380:
2375:
2371:
2367:
2363:
2356:
2353:
2348:
2344:
2340:
2336:
2332:
2328:
2321:
2318:
2313:
2309:
2305:
2301:
2296:
2291:
2287:
2283:
2279:
2275:
2271:
2264:
2261:
2256:
2252:
2247:
2242:
2238:
2234:
2230:
2226:
2222:
2215:
2212:
2207:
2203:
2199:
2195:
2190:
2185:
2181:
2177:
2173:
2169:
2165:
2158:
2155:
2150:
2146:
2141:
2136:
2132:
2128:
2124:
2120:
2116:
2109:
2106:
2101:
2097:
2092:
2087:
2083:
2079:
2075:
2071:
2067:
2060:
2058:
2054:
2049:
2045:
2044:
2039:
2034:
2023:
2020:
2015:
2011:
2006:
2001:
1997:
1993:
1989:
1985:
1981:
1974:
1971:
1966:
1962:
1957:
1952:
1948:
1944:
1941:(1): 98–112.
1940:
1936:
1932:
1925:
1922:
1917:
1913:
1909:
1905:
1900:
1895:
1891:
1887:
1883:
1876:
1873:
1868:
1864:
1859:
1854:
1849:
1844:
1840:
1836:
1832:
1825:
1823:
1819:
1814:
1810:
1809:
1804:
1799:
1788:
1786:
1782:
1777:
1773:
1769:
1765:
1760:
1755:
1751:
1747:
1743:
1736:
1733:
1728:
1724:
1719:
1714:
1710:
1706:
1702:
1698:
1694:
1687:
1684:
1679:
1675:
1670:
1665:
1660:
1655:
1651:
1647:
1643:
1636:
1633:
1628:
1624:
1619:
1614:
1610:
1606:
1602:
1598:
1597:Cell Adh Migr
1594:
1587:
1584:
1579:
1575:
1571:
1567:
1563:
1559:
1551:
1548:
1543:
1539:
1533:
1530:
1525:
1521:
1515:
1512:
1508:
1504:
1499:
1497:
1495:
1491:
1487:
1483:
1477:
1475:
1473:
1469:
1462:
1460:
1457:
1450:
1448:
1446:
1442:
1438:
1434:
1426:
1424:
1422:
1418:
1414:
1409:
1407:
1403:
1399:
1395:
1391:
1388:
1384:
1380:
1377:
1373:
1369:
1366:, as well as
1365:
1361:
1357:
1354:
1350:
1346:
1342:
1338:
1334:
1330:
1326:
1322:
1318:
1314:
1310:
1306:
1305:blood vessels
1302:
1298:
1294:
1290:
1286:
1282:
1278:
1270:
1268:
1267:
1263:
1259:
1255:
1251:
1247:
1246:MHC class III
1242:
1239:
1235:
1231:
1227:
1223:
1219:
1215:
1211:
1207:
1206:
1201:
1197:
1192:
1190:
1186:
1180:
1172:
1170:
1168:
1164:
1160:
1159:MHC class III
1156:
1148:
1143:
1141:
1139:
1135:
1127:
1125:
1123:
1118:
1115:
1113:
1110:
1106:
1102:
1098:
1094:
1090:
1078:
1073:
1069:
1065:
1062:
1058:
1051:
1049:
1046:
1042:
1038:
1034:
1031:
1027:
1023:
1016:
1010:
1006:
1003:
997:
995:
991:
987:
981:
977:
974:
970:
963:
961:
955:
951:
948:
942:
940:
936:
932:
926:
922:
919:
917:RefSeq (mRNA)
915:
908:
904:
900:
897:
891:
890:
885:
881:
878:
876:
872:
865:
864:
859:
855:
852:
846:
845:
841:
837:
832:
827:
823:
819:
815:
811:
806:
803:
801:
797:
790:
789:
784:
780:
777:
771:
770:
765:
761:
758:
756:
752:
749:
746:
744:
741:
737:
734:
730:
726:
719:
715:
710:
704:
701:
699:
696:
694:
693:cell adhesion
691:
689:
686:
684:
681:
679:
676:
675:
673:
670:
669:
663:
660:
658:
655:
653:
650:
648:
645:
643:
640:
638:
635:
633:
630:
629:
627:
624:
623:
617:
614:
612:
609:
607:
604:
602:
599:
597:
594:
593:
591:
588:
587:
584:
583:Gene ontology
580:
576:
564:
559:
556:
554:
550:
542:
537:
526:
522:
518:
514:
510:
506:
503:sciatic nerve
502:
498:
494:
490:
489:
486:
482:
477:
474:
464:
460:
456:
452:
449:right auricle
448:
444:
440:
436:
432:
429:apex of heart
428:
427:
424:
420:
415:
412:
411:
408:
406:
402:
400:
399:
395:
394:
391:
389:
385:
381:
377:
373:
365:
360:
356:
352:
347:
337:
333:
326:
319:
313:
306:
298:
294:
290:
285:
281:
276:
272:
264:
259:
255:
251:
246:
236:
232:
225:
218:
212:
205:
201:
195:
191:
187:
182:
178:
173:
169:
165:
161:
157:
153:
149:
145:
141:
137:
133:
129:
121:
116:
109:
104:
99:
88:
86:
82:
78:
72:
67:
64:
63:
59:
56:
49:
45:
40:
36:
32:
27:
22:
19:
4424:Tropoelastin
4380:
4353:
4321:
4231:
4221:
4204:
4194:
4165:
4120:
4070:
4024:
4002:
3953:
3946:
3934:
3915:
3833:
3818:
3803:
3743:
3742:
3698:
3694:
3660:
3656:
3634:(1): 53–62.
3631:
3627:
3591:
3587:
3548:
3544:
3503:
3499:
3462:
3458:
3428:(1): 48–53.
3425:
3421:
3384:
3380:
3343:
3339:
3306:
3302:
3267:
3263:
3235:(1): 64–73.
3232:
3228:
3187:
3183:
3168:. Retrieved
3138:(1): 24–30.
3135:
3131:
3102:
3098:
3063:
3059:
3025:(2): 93–98.
3022:
3018:
2982:
2978:
2949:
2945:
2889:
2885:
2875:
2838:
2834:
2788:
2784:
2777:
2744:
2740:
2733:
2700:
2696:
2690:
2647:
2643:
2637:
2604:
2600:
2594:
2559:
2555:
2545:
2510:
2506:
2496:
2461:
2457:
2447:
2410:
2406:
2396:
2369:
2365:
2355:
2333:(1): 11–19.
2330:
2326:
2320:
2277:
2274:FEBS Letters
2273:
2263:
2228:
2224:
2214:
2171:
2168:FEBS Letters
2167:
2157:
2122:
2118:
2108:
2073:
2069:
2041:
2022:
1990:(2): 77–86.
1987:
1983:
1973:
1938:
1934:
1924:
1889:
1885:
1875:
1838:
1834:
1806:
1749:
1745:
1735:
1700:
1696:
1686:
1649:
1645:
1635:
1600:
1596:
1586:
1561:
1557:
1550:
1541:
1532:
1523:
1514:
1458:
1454:
1430:
1413:osteosarcoma
1410:
1397:
1390:proteoglycan
1348:
1319:, including
1297:optic nerves
1274:
1265:
1261:
1256:can provoke
1253:
1249:
1243:
1237:
1225:
1221:
1213:
1210:complement 4
1203:
1193:
1188:
1184:
1182:
1154:
1152:
1131:
1119:
1116:
1108:
1101:glycoprotein
1096:
1092:
1088:
1087:
1012:
994:NP_001352205
983:
957:
939:NM_001365276
928:
906:
887:
861:
834:
786:
767:
747:
742:
465:tibial nerve
403:
396:
123:External IDs
74:
18:
4502:Cytokeratin
4431:Vitronectin
4112:multiplexin
3786:PDB gallery
2665:2066/185552
2562:(1): 8–26.
1886:Genes Immun
1652:: 1107787.
1646:Front Genet
1421:endothelial
1417:fibroblasts
1234:pseudogenes
491:ankle joint
362:34,938,789
349:34,879,431
261:32,115,334
248:32,041,153
101:Identifiers
4542:Categories
4133:Endostatin
4122:type XVIII
3170:2019-07-11
2841:: 612497.
2430:2115/53700
1841:. 709758.
1509:, May 2017
1488:, May 2017
1463:References
1345:perimysium
1177:See also:
1089:Tenascin X
461:myometrium
457:left ovary
407:(ortholog)
144:HomoloGene
4553:Tenascins
4512:Reticulin
4205:type VIII
2725:205001452
1353:collagens
1341:epimysium
1281:ligaments
1262:TNXA/TNXB
1128:Structure
1093:flexillin
990:NP_115859
986:NP_061978
960:NM_031176
935:NM_019105
931:NM_032470
733:Orthologs
152:GeneCards
4527:diseases
4523:See also
4466:Tectorin
4285:Leprecan
4195:type VII
4025:type XII
3948:type III
3901:Collagen
3715:19198610
3685:33878118
3677:19860791
3648:19116923
3618:19204726
3575:19143821
3532:19851445
3479:18391951
3450:23304572
3442:18091320
3413:19266077
3368:23394214
3360:18679583
3331:25061446
3323:10072631
3294:19143814
3251:18058064
3216:20041166
3164:Archived
3160:23825221
3152:16278880
3119:18588874
3090:18335242
3047:34586536
3039:17453911
3009:19738457
2966:18155129
2867:33505400
2805:17702048
2761:15558324
2717:27582382
2682:42748708
2674:11642233
2629:21274161
2621:11925569
2578:28306229
2537:27297501
2488:26075496
2439:19801846
2388:10469149
2312:13988411
2304:11322944
2255:24821840
2206:29297624
2198:17078949
2149:25793578
2100:23284009
2014:37401054
2005:10329939
1965:23241443
1916:36582994
1908:22785613
1867:34394006
1776:16267174
1768:10842355
1727:29734195
1678:37007968
1669:10050494
1627:25793578
1558:Genomics
1505:–
1484:–
1379:cytokine
1376:fibrotic
1349:in vitro
1321:pancreas
1271:Function
1105:tenascin
1061:Wikidata
712:Sources:
4507:Gelatin
4498:Keratin
4446:Decorin
4419:Elastin
4314:Laminin
4290:ADAMTS2
4264:Enzymes
4254:COL28A1
4249:COL27A1
4242:COL11A2
4237:COL11A1
4232:type XI
4226:COL10A1
4167:type VI
4164:other:
4158:COL25A1
4153:COL23A1
4148:COL17A1
4143:COL13A1
4128:COL18A1
4116:COL15A1
4072:type IV
4060:COL22A1
4055:COL21A1
4050:COL20A1
4045:COL19A1
4040:COL16A1
4035:COL14A1
4029:COL12A1
4003:type IX
3983:COL26A1
3978:COL24A1
3936:type II
3878:Protein
3723:4964308
3657:Allergy
3609:2860783
3566:2755510
3523:2758598
3487:3005450
3404:2646138
3285:2755069
3207:2791220
3081:2386751
3000:2783994
2926:2475872
2894:Bibcode
2858:7829301
2813:6760626
2769:5889106
2586:4440499
2528:4983206
2479:4525000
2347:8783183
2282:Bibcode
2246:4018787
2176:Bibcode
2140:4422802
2091:3565116
1956:3595039
1858:8362596
1718:6057477
1618:4422802
1578:8530023
1507:Ensembl
1486:Ensembl
1451:History
1445:elastin
1398:In vivo
1383:Decorin
1329:jejunum
1325:stomach
1313:ovaries
1293:kidneys
1285:tendons
1264:chimera
1167:CYP21A2
875:UniProt
800:Ensembl
739:Species
718:QuickGO
382:pattern
140:1932137
108:Aliases
4451:FAM20C
4222:type X
4215:COL8A2
4210:COL8A1
4199:COL7A1
4188:COL6A5
4183:COL6A3
4178:COL6A2
4173:COL6A1
4103:COL4A6
4098:COL4A5
4093:COL4A4
4088:COL4A3
4083:COL4A2
4078:COL4A1
4018:COL9A3
4013:COL9A2
4008:COL9A1
3971:COL5A3
3966:COL5A2
3961:COL5A1
3955:type V
3941:COL2A1
3928:COL1A2
3923:COL1A1
3917:type I
3892:matrix
3721:
3713:
3683:
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