344:
321:
218:
243:
2545:
602:
2485:
2530:
595:
2515:
350:
249:
31:
2500:
2437:
1381:
Verhagen HJ, Heijnen-Snyder GJ, Pronk A, Vroom TM, van
Vroonhoven TJ, Eikelboom BC, et al. (December 1996). "Thrombomodulin activity on mesothelial cells: perspectives for mesothelial cells as an alternative for endothelial cells for cell seeding on vascular grafts".
57:
2061:
Yonezawa S, Maruyama I, Tanaka S, Nakamura T, Sato E (August 1988). "Immunohistochemical localization of thrombomodulin in chorionic diseases of the uterus and choriocarcinoma of the stomach. A comparative study with the distribution of human chorionic gonadotropin".
1227:
pathway by forming a 1:1 stoichiometric complex with thrombin. This raises the speed of protein C activation thousandfold. Thrombomodulin-bound thrombin has procoagulant effect at the same time by inhibiting fibrinolysis by cleaving
2243:"Identification of the predominant glycosaminoglycan-attachment site in soluble recombinant human thrombomodulin: potential regulation of functionality by glycosyltransferase competition for serine474"
2212:
Srinivasan J, Hu S, Hrabal R, Zhu Y, Komives EA, Ni F (November 1994). "Thrombin-bound structure of an EGF subdomain from human thrombomodulin determined by transferred nuclear
Overhauser effects".
2022:
Shirai T, Shiojiri S, Ito H, Yamamoto S, Kusumoto H, Deyashiki Y, et al. (February 1988). "Gene structure of human thrombomodulin, a cofactor for thrombin-catalyzed activation of protein C".
3446:
1645:
Dzionek A, Inagaki Y, Okawa K, Nagafune J, RΓΆck J, Sohma Y, et al. (December 2002). "Plasmacytoid dendritic cells: from specific surface markers to specific cellular functions".
2585:
2544:
357:
256:
3436:
1254:
described as BDCA-3 has turned out to be identical to thrombomodulin. Thus, it was revealed that this molecule also occurs on a very rare (0.02%) subset of human
1993:
Wen DZ, Dittman WA, Ye RD, Deaven LL, Majerus PW, Sadler JE (July 1987). "Human thrombomodulin: complete cDNA sequence and chromosome localization of the gene".
1425:
Wen DZ, Dittman WA, Ye RD, Deaven LL, Majerus PW, Sadler JE (July 1987). "Human thrombomodulin: complete cDNA sequence and chromosome localization of the gene".
2284:
Yasuda K, Espinosa R, Davis EM, Le Beau MM, Bell GI (September 1993). "Human somatostatin receptor genes: localization of SSTR5 to human chromosome 20p11.2".
2484:
1899:"Human thrombomodulin gene is intron depleted: nucleic acid sequences of the cDNA and gene predict protein structure and suggest sites of regulatory control"
3416:
860:
841:
4278:
2602:
2578:
179:
2529:
4009:
2514:
1847:
Van de Wouwer M, Collen D, Conway EM (August 2004). "Thrombomodulin-protein C-EPCR system: integrated to regulate coagulation and inflammation".
3997:
3775:
4610:
4061:
4056:
4002:
3782:
2563:
2464:
1351:
1333:
4620:
3515:
3441:
2571:
2313:
Yamamoto S, Mizoguchi T, Tamaki T, Ohkuchi M, Kimura S, Aoki N (April 1993). "Urinary thrombomodulin, its isolation and characterization".
4544:
4539:
4534:
4529:
3456:
2075:
343:
1682:"TAFI, or plasma procarboxypeptidase B, couples the coagulation and fibrinolytic cascades through the thrombin-thrombomodulin complex"
1244:
1067:
1060:
4509:
1952:"Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation"
320:
3745:
2499:
4313:
3807:
3493:
1320:
1299:
2388:, Feldblyum TV, Durkin AS, Nierman WC (May 1996). "Radiation hybrid mapping of SNAP, PCSK2, and THBD (human chromosome 20p)".
3952:
3488:
242:
217:
2144:"The structure of a 19-residue fragment from the C-loop of the fourth epidermal growth factor-like domain of thrombomodulin"
1316:
54:
4449:
3921:
3916:
3861:
3595:
3044:
1769:"Thrombomodulin as a model of molecular mechanisms that modulate protease specificity and function at the vessel surface"
1295:
4143:
3866:
159:
4615:
3461:
2179:"The first mutation identified in the thrombomodulin gene in a 45-year-old man presenting with thromboembolic disease"
1267:
1243:
inactivation by factor I. Mutations in the thrombomodulin gene (THBD) have also been reported to be associated with
356:
255:
4173:
2598:
1127:
3039:
2457:
1131:
349:
248:
4223:
3118:
905:
167:
1606:"BDCA-2, BDCA-3, and BDCA-4: three markers for distinct subsets of dendritic cells in human peripheral blood"
4187:
1212:
886:
3530:
3525:
3520:
3510:
2817:
2745:
2031:
1876:
Boffa MC, Jackman RW, Peyri N, Boffa JF, George B (1991). "Thrombomodulin in the central nervous system".
1810:
Ohlin AK, Norlund L, Marlar RA (July 1997). "Thrombomodulin gene variations and thromboembolic disease".
2874:
2792:
231:
4111:
3824:
2450:
2036:
1910:
1200:
146:
4138:
3957:
1229:
3545:
3279:
2413:
2087:
1835:
1798:
1488:
1407:
191:
2344:"Synthesis, activity, and preliminary structure of the fourth EGF-like domain of thrombomodulin"
1043:
1022:
996:
975:
2405:
2373:
2330:
2301:
2272:
2229:
2200:
2165:
2130:
2079:
2049:
2010:
1981:
1938:
1885:
1864:
1827:
1790:
1744:
1703:
1662:
1627:
1586:
1537:
1480:
1442:
1399:
1143:
139:
47:
1950:
Suzuki K, Kusumoto H, Deyashiki Y, Nishioka J, Maruyama I, Zushi M, et al. (July 1987).
1172:
4318:
4051:
3972:
3535:
2728:
2654:
2397:
2385:
2363:
2355:
2322:
2293:
2262:
2254:
2221:
2190:
2155:
2120:
2112:
2071:
2041:
2002:
1971:
1963:
1928:
1918:
1856:
1819:
1780:
1734:
1693:
1654:
1617:
1576:
1568:
1527:
1519:
1472:
1434:
1391:
1151:
1135:
601:
436:
367:
311:
266:
4378:
2914:
2909:
2832:
2326:
2045:
1604:
Dzionek A, Fuchs A, Schmidt P, Cremer S, Zysk M, Miltenyi S, et al. (December 2000).
1555:
Delvaeye M, Noris M, De Vriese A, Esmon CT, Esmon NL, Ferrell G, et al. (July 2009).
1184:
594:
411:
187:
1914:
1395:
4163:
3096:
2899:
2368:
2343:
2267:
2242:
1967:
1860:
1723:"Macromolecular specificity determinants on thrombin for fibrinogen and thrombomodulin"
1581:
1556:
1532:
1507:
1460:
1255:
1159:
2125:
2100:
1976:
1951:
1933:
1898:
1739:
1722:
1658:
775:
770:
765:
760:
755:
750:
745:
740:
735:
730:
725:
709:
704:
699:
694:
689:
684:
679:
674:
658:
653:
648:
643:
30:
4604:
4133:
3590:
2681:
1508:"C-type lectin domain group 14 proteins in vascular biology, cancer and inflammation"
1239:
on the surface of endothelial cells that, in addition to binding thrombin, regulates
1224:
1196:
1180:
630:
2553:: FIFTH EGF-LIKE DOMAIN OF THROMBOMODULIN (TMEGF5), NMR, MINIMIZED AVERAGE STRUCTURE
2417:
2241:
Gerlitz B, Hassell T, Vlahos CJ, Parkinson JF, Bang NU, Grinnell BW (October 1993).
2091:
1839:
1802:
1492:
1368:
4489:
3797:
3787:
3318:
3284:
1411:
1236:
429:
208:
171:
1622:
1605:
195:
4499:
4148:
3926:
3901:
3600:
3222:
3148:
2622:
2195:
2178:
1785:
1768:
1356:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1338:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1903:
Proceedings of the
National Academy of Sciences of the United States of America
512:
4429:
4153:
3834:
3575:
3451:
3084:
3079:
3074:
2929:
2713:
2432:
2076:
10.1002/1097-0142(19880801)62:3<569::AID-CNCR2820620322>3.0.CO;2-T
328:
225:
175:
2160:
2143:
1698:
1681:
4268:
4263:
4258:
4248:
4243:
4238:
4233:
1923:
1220:
1192:
805:
572:
450:
395:
382:
294:
281:
183:
2359:
2297:
1868:
1823:
1666:
1631:
1590:
1541:
1476:
2409:
2401:
2377:
2334:
2305:
2276:
2233:
2204:
2169:
2134:
2083:
2053:
2014:
1985:
1942:
1889:
1831:
1794:
1748:
1707:
1572:
1484:
1446:
1403:
1107:
1102:
4574:
4474:
4288:
4273:
3476:
3471:
3379:
3069:
2142:
Adler M, Seto MH, Nitecki DE, Lin JH, Light DR, Morser J (October 1995).
1271:
1216:
1155:
1139:
1091:
950:
931:
2225:
2006:
1897:
Jackman RW, Beeler DL, Fritze L, Soff G, Rosenberg RD (September 1987).
1438:
4524:
4519:
4514:
4414:
4228:
4218:
4045:
4024:
4019:
3987:
3792:
3712:
3707:
3702:
3697:
3692:
3610:
3303:
3143:
3138:
3133:
3128:
3123:
2594:
1523:
1251:
917:
872:
2493:: FIFTH EGF-LIKE DOMAIN OF THROMBOMODULIN (TMEGF5), NMR, 14 STRUCTURES
2258:
2116:
1150:
from a procoagulant enzyme. Thrombomodulin is also expressed on human
116:
112:
108:
104:
100:
96:
92:
88:
84:
80:
76:
4464:
4424:
4409:
4393:
4388:
4368:
4363:
4298:
4106:
4076:
4040:
4031:
3844:
3812:
3676:
3671:
3641:
3620:
3580:
3540:
3406:
3384:
3343:
3267:
3262:
3257:
3252:
3247:
3242:
3111:
3106:
3101:
3049:
3034:
2904:
2894:
2857:
2852:
2770:
2765:
1188:
1147:
1075:
827:
2433:
GeneReviews/NCBI/NIH/UW entry on
Atypical Hemolytic-Uremic Syndrome
4589:
4564:
4484:
4479:
4469:
4459:
4444:
4439:
4434:
4419:
4373:
4358:
4323:
4308:
4303:
4293:
4213:
4208:
4203:
4182:
4178:
4168:
4081:
3982:
3977:
3936:
3886:
3881:
3876:
3871:
3856:
3849:
3829:
3817:
3760:
3755:
3750:
3740:
3735:
3728:
3666:
3656:
3651:
3646:
3636:
3615:
3605:
3570:
3565:
3560:
3555:
3550:
3505:
3500:
3466:
3431:
3426:
3421:
3411:
3399:
3394:
3374:
3369:
3364:
3359:
3313:
3205:
3200:
3019:
3003:
2996:
2991:
2986:
2981:
2976:
2971:
2946:
2924:
2919:
2812:
2738:
2733:
2723:
790:
786:
4584:
4579:
4569:
4559:
4554:
4549:
4504:
4494:
4454:
4383:
4353:
4348:
4343:
4338:
4333:
4328:
4283:
4253:
4158:
4126:
4121:
4101:
4091:
4086:
4071:
4066:
3967:
3962:
3931:
3911:
3906:
3896:
3891:
3770:
3723:
3683:
3338:
3333:
3328:
3323:
3308:
3299:
3294:
3289:
3274:
3232:
3227:
3217:
3212:
3195:
3190:
3185:
3180:
3175:
3170:
3165:
3160:
3155:
3091:
3064:
3059:
3054:
3029:
3024:
2961:
2956:
2951:
2941:
2936:
2889:
2884:
2879:
2869:
2864:
2847:
2842:
2837:
2827:
2822:
2807:
2802:
2797:
2787:
2782:
2777:
2760:
2755:
2750:
2701:
2669:
2664:
2659:
2642:
2637:
2632:
2627:
1557:"Thrombomodulin mutations in atypical hemolytic-uremic syndrome"
1176:
163:
2567:
2446:
1506:
Khan KA, McMurray JL, Mohammed F, Bicknell R (September 2019).
610:
150:, AHUS6, BDCA3, CD141, THPH12, THRM, TM, thrombomodulin, BDCA-3
4096:
2708:
2696:
2691:
2686:
2676:
2649:
2617:
2538:: FOURTH EGF-LIKE DOMAIN OF THROMBOMODULIN, NMR, 12 STRUCTURES
2442:
1240:
1183:, and consists of a single chain with six tandemly repeated
2523:: CRYSTAL STRUCTURE OF THE THROMBIN-THROMBOMODULIN COMPLEX
419:
2342:
Meininger DP, Hunter MJ, Komives EA (September 1995).
1463:(July 1997). "Thrombomodulin structure and function".
1232:(TAFI, aka carboxypeptidase B2) into its active form.
2101:"Thrombomodulin is present in human plasma and urine"
1258:
called MDC2. Its function on these cells is unknown.
584:
4402:
4196:
3945:
3629:
3352:
3012:
2610:
1036:
1015:
989:
968:
2438:OMIM entries on Atypical Hemolytic-Uremic Syndrome
1849:Arteriosclerosis, Thrombosis, and Vascular Biology
1312:
1310:
1308:
1291:
1289:
1287:
366:
265:
1317:GRCm38: Ensembl release 89: ENSMUSG00000074743
2579:
2458:
8:
1170:In humans, thrombomodulin is encoded by the
1680:Bajzar L, Morser J, Nesheim M (July 1996).
1296:GRCh38: Ensembl release 89: ENSG00000178726
1230:thrombin-activatable fibrinolysis inhibitor
1146:by converting thrombin to an anticoagulant
2586:
2572:
2564:
2508:: NMR STRUCTURE OF THROMBOMODULIN EGF(4-5)
2465:
2451:
2443:
801:
736:negative regulation of platelet activation
626:
407:
306:
203:
65:
2603:list of human clusters of differentiation
2367:
2266:
2194:
2159:
2124:
2035:
1975:
1932:
1922:
1784:
1738:
1697:
1621:
1580:
1531:
1179:. The protein has a molecular mass of 74k
654:transmembrane signaling receptor activity
771:negative regulation of blood coagulation
2480:
1283:
16:Mammalian protein found in Homo sapiens
1878:Nouvelle Revue Française d'Hématologie
20:
2327:10.1093/oxfordjournals.jbchem.a124063
2105:The Journal of Clinical Investigation
2099:Ishii H, Majerus PW (December 1985).
2046:10.1093/oxfordjournals.jbchem.a122261
690:integral component of plasma membrane
371:
332:
327:
270:
229:
224:
7:
2177:Ohlin AK, Marlar RA (January 1995).
1721:Jakubowski HV, Owen WG (July 1989).
2148:The Journal of Biological Chemistry
1727:The Journal of Biological Chemistry
1686:The Journal of Biological Chemistry
1561:The New England Journal of Medicine
1396:10.1046/j.1365-2141.1996.d01-1935.x
751:negative regulation of fibrinolysis
1968:10.1002/j.1460-2075.1987.tb02448.x
1861:10.1161/01.ATV.0000134298.25489.92
1245:atypical hemolytic-uremic syndrome
1033:
1012:
986:
965:
941:
922:
896:
877:
851:
832:
589:
507:
445:
424:
14:
1266:Thrombomodulin has been shown to
2543:
2528:
2513:
2498:
2483:
600:
593:
355:
348:
342:
319:
254:
247:
241:
216:
29:
1384:British Journal of Haematology
1211:Thrombomodulin functions as a
1199:domain. It is a member of the
741:response to lipopolysaccharide
675:integral component of membrane
611:More reference expression data
573:More reference expression data
1:
1740:10.1016/S0021-9258(18)60437-5
1659:10.1016/S0198-8859(02)00752-8
1138:and serves as a cofactor for
340:
239:
4611:Genes on human chromosome 20
1623:10.4049/jimmunol.165.11.6037
1134:expressed on the surface of
700:apicolateral plasma membrane
4621:Clusters of differentiation
2599:clusters of differentiation
2196:10.1182/blood.V85.2.330.330
1786:10.1096/fasebj.9.10.7615164
659:signaling receptor activity
4637:
1812:Thrombosis and Haemostasis
1465:Thrombosis and Haemostasis
1371:Accessed January 19, 2012.
2478:
1352:"Mouse PubMed Reference:"
1334:"Human PubMed Reference:"
1132:integral membrane protein
1106:
1101:
1097:
1090:
1074:
1068:Chr 2: 148.25 β 148.25 Mb
1055:
1040:
1019:
1008:
993:
972:
961:
948:
944:
929:
925:
916:
903:
899:
884:
880:
871:
858:
854:
839:
835:
826:
811:
804:
800:
784:
629:
625:
608:
592:
583:
570:
519:
510:
457:
448:
418:
410:
406:
389:
376:
339:
318:
309:
305:
288:
275:
238:
215:
206:
202:
157:
154:
144:
137:
132:
73:
68:
51:
46:
41:
37:
28:
23:
2161:10.1074/jbc.270.40.23366
1699:10.1074/jbc.271.28.16603
1369:IPR001491 Thrombomodulin
1203:(CTLD) group 14 family.
1061:Chr 20: 23.05 β 23.05 Mb
2315:Journal of Biochemistry
2247:The Biochemical Journal
2024:Journal of Biochemistry
1924:10.1073/pnas.84.18.6425
1219:-induced activation of
493:upper lobe of left lung
2360:10.1002/pro.5560040904
2298:10.1006/geno.1993.1410
1824:10.1055/s-0038-1657559
1767:Esmon CT (July 1995).
1477:10.1055/s-0038-1657558
1166:Genetics and structure
2402:10.1007/s003359900120
1610:Journal of Immunology
1573:10.1056/NEJMoa0810739
232:Chromosome 20 (human)
1235:Thrombomodulin is a
1201:C-type lectin domain
1130:141 or BDCA-3 is an
555:white adipose tissue
497:left coronary artery
373:2 G3|2 73.45 cM
334:Chromosome 2 (mouse)
69:List of PDB id codes
42:Available structures
2226:10.1021/bi00250a007
2220:(46): 13553β13560.
2154:(40): 23366β23372.
2007:10.1021/bi00388a025
1915:1987PNAS...84.6425J
1733:(19): 11117β11121.
1692:(28): 16603β16608.
1439:10.1021/bi00388a025
1195:-rich spacer and a
776:leukocyte migration
766:signal transduction
710:extracellular space
644:calcium ion binding
461:gingival epithelium
4616:Coagulation system
1524:10.1111/febs.14985
906:ENSMUSG00000074743
719:Biological process
668:Cellular component
637:Molecular function
489:lower lobe of lung
4598:
4597:
2561:
2560:
2259:10.1042/bj2950131
2117:10.1172/JCI112225
2001:(14): 4350β4357.
1909:(18): 6425β6429.
1653:(12): 1133β1148.
1616:(11): 6037β6046.
1518:(17): 3299β3332.
1433:(14): 4350β4357.
1144:blood coagulation
1136:endothelial cells
1117:
1116:
1113:
1112:
1086:
1085:
1051:
1050:
1030:
1029:
1004:
1003:
983:
982:
957:
956:
938:
937:
912:
911:
893:
892:
867:
866:
848:
847:
796:
795:
761:response to X-ray
756:blood coagulation
705:vacuolar membrane
621:
620:
617:
616:
579:
578:
566:
565:
504:
503:
485:periodontal fiber
402:
401:
301:
300:
128:
127:
124:
123:
52:Ortholog search:
4628:
2588:
2581:
2574:
2565:
2547:
2532:
2517:
2502:
2487:
2467:
2460:
2453:
2444:
2421:
2390:Mammalian Genome
2381:
2371:
2354:(9): 1683β1695.
2338:
2309:
2280:
2270:
2237:
2208:
2198:
2173:
2163:
2138:
2128:
2111:(6): 2178β2181.
2095:
2057:
2039:
2037:10.1.1.1006.6759
2018:
1989:
1979:
1962:(7): 1891β1897.
1956:The EMBO Journal
1946:
1936:
1926:
1893:
1872:
1855:(8): 1374β1383.
1843:
1806:
1788:
1753:
1752:
1742:
1718:
1712:
1711:
1701:
1677:
1671:
1670:
1647:Human Immunology
1642:
1636:
1635:
1625:
1601:
1595:
1594:
1584:
1552:
1546:
1545:
1535:
1512:The FEBS Journal
1503:
1497:
1496:
1457:
1451:
1450:
1422:
1416:
1415:
1378:
1372:
1366:
1360:
1359:
1348:
1342:
1341:
1330:
1324:
1314:
1303:
1293:
1185:EGF-like domains
1152:mesothelial cell
1099:
1098:
1070:
1063:
1046:
1034:
1025:
1013:
1009:RefSeq (protein)
999:
987:
978:
966:
942:
923:
897:
878:
852:
833:
802:
746:response to cAMP
731:female pregnancy
627:
613:
604:
597:
590:
575:
515:
513:Top expressed in
508:
453:
451:Top expressed in
446:
425:
408:
398:
385:
374:
359:
352:
346:
335:
323:
307:
297:
284:
273:
258:
251:
245:
234:
220:
204:
198:
196:THBD - orthologs
149:
142:
119:
66:
60:
39:
38:
33:
21:
4636:
4635:
4631:
4630:
4629:
4627:
4626:
4625:
4601:
4600:
4599:
4594:
4398:
4192:
3941:
3625:
3348:
3008:
2606:
2592:
2562:
2557:
2554:
2548:
2539:
2533:
2524:
2518:
2509:
2503:
2494:
2488:
2474:
2471:
2429:
2424:
2384:
2348:Protein Science
2341:
2312:
2283:
2240:
2211:
2176:
2141:
2098:
2060:
2021:
1992:
1949:
1896:
1875:
1846:
1809:
1779:(10): 946β955.
1766:
1762:
1760:Further reading
1757:
1756:
1720:
1719:
1715:
1679:
1678:
1674:
1644:
1643:
1639:
1603:
1602:
1598:
1554:
1553:
1549:
1505:
1504:
1500:
1459:
1458:
1454:
1424:
1423:
1419:
1380:
1379:
1375:
1367:
1363:
1350:
1349:
1345:
1332:
1331:
1327:
1315:
1306:
1294:
1285:
1280:
1264:
1256:dendritic cells
1209:
1168:
1108:View/Edit Mouse
1103:View/Edit Human
1066:
1059:
1056:Location (UCSC)
1042:
1021:
995:
974:
887:ENSG00000178726
780:
714:
685:plasma membrane
663:
649:protein binding
609:
599:
598:
571:
562:
557:
553:
551:ascending aorta
549:
545:
541:
537:
533:
529:
525:
523:right lung lobe
511:
500:
495:
491:
487:
483:
479:
477:skin of abdomen
475:
471:
467:
463:
449:
393:
380:
372:
362:
361:
360:
353:
333:
310:Gene location (
292:
279:
271:
261:
260:
259:
252:
230:
207:Gene location (
158:
145:
138:
75:
53:
17:
12:
11:
5:
4634:
4632:
4624:
4623:
4618:
4613:
4603:
4602:
4596:
4595:
4593:
4592:
4587:
4582:
4577:
4572:
4567:
4562:
4557:
4552:
4547:
4542:
4537:
4532:
4527:
4522:
4517:
4512:
4507:
4502:
4497:
4492:
4487:
4482:
4477:
4472:
4467:
4462:
4457:
4452:
4447:
4442:
4437:
4432:
4427:
4422:
4417:
4412:
4406:
4404:
4400:
4399:
4397:
4396:
4391:
4386:
4381:
4376:
4371:
4366:
4361:
4356:
4351:
4346:
4341:
4336:
4331:
4326:
4321:
4316:
4311:
4306:
4301:
4296:
4291:
4286:
4281:
4276:
4271:
4266:
4261:
4256:
4251:
4246:
4241:
4236:
4231:
4226:
4221:
4216:
4211:
4206:
4200:
4198:
4194:
4193:
4191:
4190:
4185:
4176:
4171:
4166:
4161:
4156:
4151:
4146:
4141:
4136:
4131:
4130:
4129:
4124:
4114:
4109:
4104:
4099:
4094:
4089:
4084:
4079:
4074:
4069:
4064:
4059:
4054:
4049:
4043:
4034:
4029:
4028:
4027:
4022:
4012:
4007:
4006:
4005:
4000:
3990:
3985:
3980:
3975:
3970:
3965:
3960:
3955:
3949:
3947:
3943:
3942:
3940:
3939:
3934:
3929:
3924:
3919:
3914:
3909:
3904:
3899:
3894:
3889:
3884:
3879:
3874:
3869:
3864:
3859:
3854:
3853:
3852:
3847:
3837:
3832:
3827:
3822:
3821:
3820:
3815:
3810:
3800:
3795:
3790:
3785:
3780:
3779:
3778:
3773:
3763:
3758:
3753:
3748:
3743:
3738:
3733:
3732:
3731:
3726:
3716:
3710:
3705:
3700:
3695:
3686:
3681:
3680:
3679:
3674:
3669:
3659:
3654:
3649:
3644:
3639:
3633:
3631:
3627:
3626:
3624:
3623:
3618:
3613:
3608:
3603:
3598:
3593:
3588:
3583:
3578:
3573:
3568:
3563:
3558:
3553:
3548:
3543:
3538:
3533:
3528:
3523:
3518:
3513:
3508:
3503:
3498:
3497:
3496:
3491:
3481:
3480:
3479:
3474:
3464:
3459:
3454:
3449:
3444:
3439:
3434:
3429:
3424:
3419:
3414:
3409:
3404:
3403:
3402:
3397:
3387:
3382:
3377:
3372:
3367:
3362:
3356:
3354:
3350:
3349:
3347:
3346:
3341:
3336:
3331:
3326:
3321:
3316:
3311:
3306:
3297:
3292:
3287:
3282:
3277:
3272:
3271:
3270:
3265:
3260:
3255:
3250:
3245:
3235:
3230:
3225:
3220:
3215:
3210:
3209:
3208:
3203:
3193:
3188:
3183:
3178:
3173:
3168:
3163:
3158:
3153:
3152:
3151:
3146:
3141:
3136:
3131:
3126:
3116:
3115:
3114:
3109:
3104:
3094:
3089:
3088:
3087:
3082:
3077:
3067:
3062:
3057:
3052:
3047:
3042:
3037:
3032:
3027:
3022:
3016:
3014:
3010:
3009:
3007:
3006:
3001:
3000:
2999:
2994:
2989:
2984:
2979:
2974:
2964:
2959:
2954:
2949:
2944:
2939:
2934:
2933:
2932:
2927:
2922:
2917:
2907:
2902:
2897:
2892:
2887:
2882:
2877:
2872:
2867:
2862:
2861:
2860:
2855:
2845:
2840:
2835:
2830:
2825:
2820:
2815:
2810:
2805:
2800:
2795:
2790:
2785:
2780:
2775:
2774:
2773:
2768:
2758:
2753:
2748:
2743:
2742:
2741:
2736:
2731:
2726:
2716:
2711:
2706:
2705:
2704:
2694:
2689:
2684:
2679:
2674:
2673:
2672:
2667:
2662:
2652:
2647:
2646:
2645:
2640:
2635:
2630:
2625:
2614:
2612:
2608:
2607:
2593:
2591:
2590:
2583:
2576:
2568:
2559:
2558:
2556:
2555:
2549:
2542:
2540:
2534:
2527:
2525:
2519:
2512:
2510:
2504:
2497:
2495:
2489:
2482:
2479:
2476:
2475:
2472:
2470:
2469:
2462:
2455:
2447:
2441:
2440:
2435:
2428:
2427:External links
2425:
2423:
2422:
2396:(5): 400β401.
2382:
2339:
2321:(4): 433β440.
2310:
2292:(3): 785β786.
2281:
2253:(1): 131β140.
2238:
2209:
2189:(2): 330β336.
2174:
2139:
2096:
2070:(3): 569β576.
2058:
2030:(2): 281β285.
2019:
1990:
1947:
1894:
1884:(6): 423β429.
1873:
1844:
1818:(1): 396β400.
1807:
1763:
1761:
1758:
1755:
1754:
1713:
1672:
1637:
1596:
1567:(4): 345β357.
1547:
1498:
1471:(1): 392β395.
1452:
1417:
1390:(3): 542β549.
1373:
1361:
1343:
1325:
1304:
1282:
1281:
1279:
1276:
1263:
1260:
1208:
1205:
1167:
1164:
1160:dendritic cell
1120:Thrombomodulin
1115:
1114:
1111:
1110:
1105:
1095:
1094:
1088:
1087:
1084:
1083:
1081:
1079:
1072:
1071:
1064:
1057:
1053:
1052:
1049:
1048:
1038:
1037:
1031:
1028:
1027:
1017:
1016:
1010:
1006:
1005:
1002:
1001:
991:
990:
984:
981:
980:
970:
969:
963:
959:
958:
955:
954:
946:
945:
939:
936:
935:
927:
926:
920:
914:
913:
910:
909:
901:
900:
894:
891:
890:
882:
881:
875:
869:
868:
865:
864:
856:
855:
849:
846:
845:
837:
836:
830:
824:
823:
818:
813:
809:
808:
798:
797:
794:
793:
782:
781:
779:
778:
773:
768:
763:
758:
753:
748:
743:
738:
733:
728:
722:
720:
716:
715:
713:
712:
707:
702:
697:
692:
687:
682:
677:
671:
669:
665:
664:
662:
661:
656:
651:
646:
640:
638:
634:
633:
623:
622:
619:
618:
615:
614:
606:
605:
587:
581:
580:
577:
576:
568:
567:
564:
563:
561:
560:
556:
552:
548:
544:
540:
536:
532:
531:left lung lobe
528:
524:
520:
517:
516:
505:
502:
501:
499:
498:
494:
490:
486:
482:
478:
474:
470:
466:
462:
458:
455:
454:
442:
441:
433:
422:
416:
415:
412:RNA expression
404:
403:
400:
399:
391:
387:
386:
378:
375:
370:
364:
363:
354:
347:
341:
337:
336:
331:
325:
324:
316:
315:
303:
302:
299:
298:
290:
286:
285:
277:
274:
269:
263:
262:
253:
246:
240:
236:
235:
228:
222:
221:
213:
212:
200:
199:
156:
152:
151:
143:
135:
134:
130:
129:
126:
125:
122:
121:
71:
70:
62:
61:
50:
44:
43:
35:
34:
26:
25:
15:
13:
10:
9:
6:
4:
3:
2:
4633:
4622:
4619:
4617:
4614:
4612:
4609:
4608:
4606:
4591:
4588:
4586:
4583:
4581:
4578:
4576:
4573:
4571:
4568:
4566:
4563:
4561:
4558:
4556:
4553:
4551:
4548:
4546:
4543:
4541:
4538:
4536:
4533:
4531:
4528:
4526:
4523:
4521:
4518:
4516:
4513:
4511:
4508:
4506:
4503:
4501:
4498:
4496:
4493:
4491:
4488:
4486:
4483:
4481:
4478:
4476:
4473:
4471:
4468:
4466:
4463:
4461:
4458:
4456:
4453:
4451:
4448:
4446:
4443:
4441:
4438:
4436:
4433:
4431:
4428:
4426:
4423:
4421:
4418:
4416:
4413:
4411:
4408:
4407:
4405:
4401:
4395:
4392:
4390:
4387:
4385:
4382:
4380:
4377:
4375:
4372:
4370:
4367:
4365:
4362:
4360:
4357:
4355:
4352:
4350:
4347:
4345:
4342:
4340:
4337:
4335:
4332:
4330:
4327:
4325:
4322:
4320:
4317:
4315:
4312:
4310:
4307:
4305:
4302:
4300:
4297:
4295:
4292:
4290:
4287:
4285:
4282:
4280:
4277:
4275:
4272:
4270:
4267:
4265:
4262:
4260:
4257:
4255:
4252:
4250:
4247:
4245:
4242:
4240:
4237:
4235:
4232:
4230:
4227:
4225:
4222:
4220:
4217:
4215:
4212:
4210:
4207:
4205:
4202:
4201:
4199:
4195:
4189:
4186:
4184:
4180:
4177:
4175:
4172:
4170:
4167:
4165:
4162:
4160:
4157:
4155:
4152:
4150:
4147:
4145:
4142:
4140:
4137:
4135:
4132:
4128:
4125:
4123:
4120:
4119:
4118:
4115:
4113:
4110:
4108:
4105:
4103:
4100:
4098:
4095:
4093:
4090:
4088:
4085:
4083:
4080:
4078:
4075:
4073:
4070:
4068:
4065:
4063:
4060:
4058:
4055:
4053:
4050:
4047:
4044:
4042:
4038:
4035:
4033:
4030:
4026:
4023:
4021:
4018:
4017:
4016:
4013:
4011:
4008:
4004:
4001:
3999:
3996:
3995:
3994:
3991:
3989:
3986:
3984:
3981:
3979:
3976:
3974:
3971:
3969:
3966:
3964:
3961:
3959:
3956:
3954:
3951:
3950:
3948:
3944:
3938:
3935:
3933:
3930:
3928:
3925:
3923:
3920:
3918:
3915:
3913:
3910:
3908:
3905:
3903:
3900:
3898:
3895:
3893:
3890:
3888:
3885:
3883:
3880:
3878:
3875:
3873:
3870:
3868:
3865:
3863:
3860:
3858:
3855:
3851:
3848:
3846:
3843:
3842:
3841:
3838:
3836:
3833:
3831:
3828:
3826:
3823:
3819:
3816:
3814:
3811:
3809:
3806:
3805:
3804:
3801:
3799:
3796:
3794:
3791:
3789:
3786:
3784:
3781:
3777:
3774:
3772:
3769:
3768:
3767:
3764:
3762:
3759:
3757:
3754:
3752:
3749:
3747:
3744:
3742:
3739:
3737:
3734:
3730:
3727:
3725:
3722:
3721:
3720:
3717:
3714:
3711:
3709:
3706:
3704:
3701:
3699:
3696:
3694:
3690:
3687:
3685:
3682:
3678:
3675:
3673:
3670:
3668:
3665:
3664:
3663:
3660:
3658:
3655:
3653:
3650:
3648:
3645:
3643:
3640:
3638:
3635:
3634:
3632:
3628:
3622:
3619:
3617:
3614:
3612:
3609:
3607:
3604:
3602:
3599:
3597:
3594:
3592:
3589:
3587:
3584:
3582:
3579:
3577:
3574:
3572:
3569:
3567:
3564:
3562:
3559:
3557:
3554:
3552:
3549:
3547:
3544:
3542:
3539:
3537:
3534:
3532:
3529:
3527:
3524:
3522:
3519:
3517:
3514:
3512:
3509:
3507:
3504:
3502:
3499:
3495:
3492:
3490:
3487:
3486:
3485:
3482:
3478:
3475:
3473:
3470:
3469:
3468:
3465:
3463:
3460:
3458:
3455:
3453:
3450:
3448:
3445:
3443:
3440:
3438:
3435:
3433:
3430:
3428:
3425:
3423:
3420:
3418:
3415:
3413:
3410:
3408:
3405:
3401:
3398:
3396:
3393:
3392:
3391:
3388:
3386:
3383:
3381:
3378:
3376:
3373:
3371:
3368:
3366:
3363:
3361:
3358:
3357:
3355:
3351:
3345:
3342:
3340:
3337:
3335:
3332:
3330:
3327:
3325:
3322:
3320:
3317:
3315:
3312:
3310:
3307:
3305:
3301:
3298:
3296:
3293:
3291:
3288:
3286:
3283:
3281:
3278:
3276:
3273:
3269:
3266:
3264:
3261:
3259:
3256:
3254:
3251:
3249:
3246:
3244:
3241:
3240:
3239:
3236:
3234:
3231:
3229:
3226:
3224:
3221:
3219:
3216:
3214:
3211:
3207:
3204:
3202:
3199:
3198:
3197:
3194:
3192:
3189:
3187:
3184:
3182:
3179:
3177:
3174:
3172:
3169:
3167:
3164:
3162:
3159:
3157:
3154:
3150:
3147:
3145:
3142:
3140:
3137:
3135:
3132:
3130:
3127:
3125:
3122:
3121:
3120:
3117:
3113:
3110:
3108:
3105:
3103:
3100:
3099:
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2025:
2020:
2016:
2012:
2008:
2004:
2000:
1996:
1991:
1987:
1983:
1978:
1973:
1969:
1965:
1961:
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1773:FASEB Journal
1770:
1765:
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1736:
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1728:
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1409:
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1397:
1393:
1389:
1385:
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1374:
1370:
1365:
1362:
1357:
1353:
1347:
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1339:
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1329:
1326:
1322:
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1297:
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1269:
1261:
1259:
1257:
1253:
1248:
1246:
1242:
1238:
1233:
1231:
1226:
1225:anticoagulant
1222:
1218:
1214:
1206:
1204:
1202:
1198:
1197:transmembrane
1194:
1190:
1186:
1182:
1178:
1175:
1174:
1165:
1163:
1161:
1157:
1153:
1149:
1145:
1142:. It reduces
1141:
1137:
1133:
1129:
1125:
1121:
1109:
1104:
1100:
1096:
1093:
1089:
1082:
1080:
1077:
1073:
1069:
1065:
1062:
1058:
1054:
1047:
1045:
1039:
1035:
1032:
1026:
1024:
1018:
1014:
1011:
1007:
1000:
998:
992:
988:
985:
979:
977:
971:
967:
964:
962:RefSeq (mRNA)
960:
953:
952:
947:
943:
940:
934:
933:
928:
924:
921:
919:
915:
908:
907:
902:
898:
895:
889:
888:
883:
879:
876:
874:
870:
863:
862:
857:
853:
850:
844:
843:
838:
834:
831:
829:
825:
822:
819:
817:
814:
810:
807:
803:
799:
792:
788:
783:
777:
774:
772:
769:
767:
764:
762:
759:
757:
754:
752:
749:
747:
744:
742:
739:
737:
734:
732:
729:
727:
724:
723:
721:
718:
717:
711:
708:
706:
703:
701:
698:
696:
693:
691:
688:
686:
683:
681:
678:
676:
673:
672:
670:
667:
666:
660:
657:
655:
652:
650:
647:
645:
642:
641:
639:
636:
635:
632:
631:Gene ontology
628:
624:
612:
607:
603:
596:
591:
588:
586:
582:
574:
569:
558:
554:
550:
546:
542:
539:Gonadal ridge
538:
534:
530:
526:
522:
521:
518:
514:
509:
506:
496:
492:
488:
484:
481:skin of thigh
480:
476:
472:
468:
464:
460:
459:
456:
452:
447:
444:
443:
440:
438:
434:
432:
431:
427:
426:
423:
421:
417:
413:
409:
405:
397:
392:
388:
384:
379:
369:
365:
358:
351:
345:
338:
330:
326:
322:
317:
313:
308:
304:
296:
291:
287:
283:
278:
268:
264:
257:
250:
244:
237:
233:
227:
223:
219:
214:
210:
205:
201:
197:
193:
189:
185:
181:
177:
173:
169:
165:
161:
153:
148:
141:
136:
131:
120:
118:
114:
110:
106:
102:
98:
94:
90:
86:
82:
78:
72:
67:
64:
63:
59:
56:
49:
45:
40:
36:
32:
27:
22:
19:
4116:
4036:
4014:
3992:
3839:
3802:
3765:
3718:
3688:
3661:
3585:
3483:
3389:
3237:
2966:
2718:
2550:
2535:
2520:
2505:
2490:
2393:
2389:
2351:
2347:
2318:
2314:
2289:
2285:
2250:
2246:
2217:
2214:Biochemistry
2213:
2186:
2182:
2151:
2147:
2108:
2104:
2067:
2063:
2027:
2023:
1998:
1995:Biochemistry
1994:
1959:
1955:
1906:
1902:
1881:
1877:
1852:
1848:
1815:
1811:
1776:
1772:
1730:
1726:
1716:
1689:
1685:
1675:
1650:
1646:
1640:
1613:
1609:
1599:
1564:
1560:
1550:
1515:
1511:
1501:
1468:
1464:
1455:
1430:
1427:Biochemistry
1426:
1420:
1387:
1383:
1376:
1364:
1355:
1346:
1337:
1328:
1265:
1262:Interactions
1249:
1237:glycoprotein
1234:
1210:
1171:
1169:
1123:
1119:
1118:
1041:
1020:
994:
973:
949:
930:
904:
885:
859:
840:
820:
815:
680:cell surface
547:aortic valve
435:
428:
394:148,250,108
381:148,246,386
155:External IDs
74:
18:
2473:PDB gallery
473:skin of hip
293:23,049,672
280:23,045,633
133:Identifiers
4605:Categories
2601:(see also
2386:Maglott DR
1323:, May 2017
1302:, May 2017
1278:References
726:hemostasis
469:right lung
439:(ortholog)
176:HomoloGene
2032:CiteSeerX
1461:Sadler JE
1221:protein C
1193:Threonine
1044:NP_033404
1023:NP_000352
997:NM_009378
976:NM_000361
806:Orthologs
527:left lung
465:vena cava
184:GeneCards
2595:Proteins
2418:34951074
2286:Genomics
2092:28744944
1869:15178554
1840:25122238
1803:19565674
1667:12480257
1632:11086035
1591:19625716
1542:31287944
1493:32297505
1319:–
1298:–
1272:thrombin
1268:interact
1247:(aHUS).
1217:thrombin
1213:cofactor
1207:Function
1162:subset.
1156:monocyte
1140:thrombin
1092:Wikidata
785:Sources:
695:membrane
535:calvaria
272:20p11.21
4403:301β350
4197:251β300
4149:CD240CE
3946:201β250
3630:151β200
3353:101β150
2410:8661740
2378:8528067
2369:2143218
2335:8390446
2306:8244401
2277:8216207
2268:1134829
2234:7947766
2205:7811989
2170:7559494
2135:3001144
2084:2839283
2054:2836377
2015:2822087
1986:2820710
1943:2819876
1911:Bibcode
1890:1667949
1832:9198186
1795:7615164
1749:2544585
1708:8663147
1582:3530919
1533:6852297
1485:9198185
1447:2822087
1412:8417511
1404:8943899
1321:Ensembl
1300:Ensembl
1252:antigen
1223:in the
1215:in the
918:UniProt
873:Ensembl
812:Species
791:QuickGO
559:decidua
414:pattern
140:Aliases
4410:CD300A
4369:CDw293
4154:CD240D
4015:CD213a
3993:CDw210
3958:CD202b
3932:CDw199
3927:CDw198
3581:CD140b
3013:51β100
2416:
2408:
2376:
2366:
2333:
2304:
2275:
2265:
2232:
2203:
2168:
2133:
2126:424339
2123:
2090:
2082:
2064:Cancer
2052:
2034:
2013:
1984:
1977:553573
1974:
1941:
1934:299089
1931:
1888:
1867:
1838:
1830:
1801:
1793:
1747:
1706:
1665:
1630:
1589:
1579:
1540:
1530:
1491:
1483:
1445:
1410:
1402:
1189:Serine
1158:and a
1148:enzyme
1078:search
1076:PubMed
951:P15306
932:P07204
828:Entrez
585:BioGPS
164:188040
4590:CD350
4585:CD349
4580:CD344
4575:CD340
4570:CD339
4565:CD338
4560:CD337
4555:CD336
4550:CD335
4545:CD334
4540:CD333
4535:CD332
4530:CD331
4525:CD329
4520:CD328
4515:CD327
4510:CD326
4505:CD325
4500:CD324
4495:CD322
4490:CD321
4485:CD320
4480:CD318
4475:CD317
4470:CD316
4465:CD315
4460:CD314
4455:CD312
4450:CD309
4445:CD307
4440:CD306
4435:CD305
4430:CD304
4425:CD303
4420:CD302
4415:CD301
4394:CD299
4389:CD298
4384:CD297
4379:CD295
4374:CD294
4364:CD292
4359:CD290
4354:CD289
4349:CD288
4344:CD286
4339:CD284
4334:CD283
4329:CD282
4324:CD281
4319:CD280
4314:CD279
4309:CD278
4304:CD276
4299:CD275
4294:CD274
4289:CD273
4284:CD272
4279:CD271
4274:CD269
4269:CD268
4264:CD267
4259:CD266
4254:CD265
4249:CD264
4244:CD263
4239:CD262
4234:CD261
4229:CD258
4224:CD257
4219:CD256
4214:CD254
4209:CD253
4204:CD252
4188:CD249
4183:CD248
4179:CD247
4174:CD246
4169:CD244
4164:CD243
4159:CD241
4144:CD239
4139:CD238
4134:CD236
4117:CD235
4112:CD234
4107:CD233
4102:CD230
4097:CD229
4092:CD228
4087:CD227
4082:CD226
4077:CD225
4072:CD224
4067:CD223
4062:CD222
4057:CD221
4052:CD220
4037:CD218
4032:CD217
4010:CD212
3988:CD209
3983:CD208
3978:CD207
3973:CD206
3968:CD205
3963:CD204
3953:CD201
3937:CD200
3922:CD197
3917:CD196
3912:CD195
3907:CD194
3902:CD193
3897:CD192
3892:CD191
3887:CD186
3882:CD185
3877:CD184
3872:CD183
3867:CD182
3862:CD181
3857:CD180
3840:CD179
3835:CD178
3830:CD177
3825:CD174
3803:CD172
3798:CD171
3793:CD170
3788:CD169
3783:CD168
3766:CD167
3761:CD166
3756:CD164
3751:CD163
3746:CD162
3741:CD161
3736:CD160
3719:CD159
3689:CD158
3684:CD157
3662:CD156
3657:CD155
3652:CD154
3647:CD153
3642:CD152
3637:CD151
3621:CD150
3616:CD148
3611:CD147
3606:CD146
3601:CD144
3596:CD143
3591:CD142
3586:CD141
3576:CD138
3571:CD137
3566:CD136
3561:CD135
3556:CD134
3551:CD133
3546:CD132
3541:CD131
3536:CD130
3531:CD129
3526:CD127
3521:CD126
3516:CD125
3511:CD124
3506:CD123
3501:CD122
3484:CD121
3467:CD120
3462:CD119
3457:CD118
3452:CD117
3447:CD116
3442:CD115
3437:CD114
3432:CD113
3427:CD112
3422:CD111
3417:CD110
3412:CD109
3407:CD108
3390:CD107
3385:CD106
3380:CD105
3375:CD104
3370:CD103
3365:CD102
3360:CD101
3344:CD100
2414:S2CID
2183:Blood
2088:S2CID
1836:S2CID
1799:S2CID
1489:S2CID
1408:S2CID
1270:with
861:21824
821:Mouse
816:Human
787:Amigo
543:ankle
437:Mouse
430:Human
377:Start
312:Mouse
276:Start
209:Human
172:98736
3339:CD99
3334:CD98
3329:CD97
3324:CD96
3319:CD95
3314:CD94
3309:CD93
3304:CD92
3300:CD91
3295:CD90
3290:CD89
3285:CD88
3280:CD87
3275:CD86
3238:CD85
3233:CD84
3228:CD83
3223:CD82
3218:CD81
3213:CD80
3196:CD79
3191:CD78
3186:CD74
3181:CD73
3176:CD72
3171:CD71
3166:CD70
3161:CD69
3156:CD68
3119:CD66
3097:CD64
3092:CD63
3070:CD62
3065:CD61
3060:CD59
3055:CD58
3050:CD57
3045:CD56
3040:CD55
3035:CD54
3030:CD53
3025:CD52
3020:CD51
3004:CD50
2967:CD49
2962:CD48
2957:CD47
2952:CD46
2947:CD45
2942:CD44
2937:CD43
2910:CD42
2905:CD41
2900:CD40
2895:CD39
2890:CD38
2885:CD37
2880:CD36
2875:CD35
2870:CD34
2865:CD33
2848:CD32
2843:CD31
2838:CD30
2833:CD29
2828:CD28
2823:CD27
2818:CD26
2813:CD25
2808:CD24
2803:CD23
2798:CD22
2793:CD21
2788:CD20
2783:CD19
2778:CD18
2761:CD16
2756:CD15
2751:CD14
2746:CD13
2719:CD11
2714:CD10
2611:1β50
2551:2adx
2536:1zaq
2521:1dx5
2506:1dqb
2491:1adx
2406:PMID
2374:PMID
2331:PMID
2302:PMID
2273:PMID
2230:PMID
2201:PMID
2166:PMID
2131:PMID
2080:PMID
2050:PMID
2011:PMID
1982:PMID
1939:PMID
1886:PMID
1865:PMID
1828:PMID
1791:PMID
1745:PMID
1704:PMID
1663:PMID
1628:PMID
1587:PMID
1538:PMID
1481:PMID
1443:PMID
1400:PMID
1250:The
1187:, a
1177:gene
1173:THBD
842:7056
420:Bgee
368:Band
329:Chr.
267:Band
226:Chr.
188:THBD
160:OMIM
147:THBD
117:3GIS
113:2ADX
109:1ZAQ
105:1TMR
101:1HLT
97:1FGE
93:1FGD
89:1EGT
85:1DX5
81:1DQB
77:1ADX
58:RCSB
55:PDBe
24:THBD
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