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Alpha 1-antitrypsin comprised 50% of the total protein in Tracy's milk, a remarkably high level maintained after lactation. Similar levels were detected in the milk produced by her granddaughters. A deficiency in this protein in humans can produce lung diseases, and its artificial creation was
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thought to be a potential success in the diseases' treatment. Clinical trials for the engineered protein in 1998 revealed that it developed breathing problems in patients, and research for the milk as a remedy for the diseases has not continued since then.
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39:. Notably, she is the first transgenic farm mammal ever created.
107:"Animal Pharming: The Industrialization of Transgenic Animals"
134:Castro, Fidel O.; Jänne, Juhani (4 October 2014).
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82:"Tracy, a transgenic sheep, Scotland, 1999"
23:sheep created by scientists at Scotland's
159:Newton PhD, David E. (12 November 2009).
195:Individual animals in the United Kingdom
138:(1998 ed.). Springer. p. 167.
114:United States Department of Agriculture
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161:DNA Technology: A Reference Handbook
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63:Genetically modified organisms
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27:to produce the human protein
136:Mammary Glands Transgenesis
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86:www.sciencemuseum.org.uk
163:. ABC-CLIO. p. 25.
21:transgenically modified
19:(1990 – 1997) was a
58:Pharming (genetics)
29:alpha 1-antitrypsin
190:1997 animal deaths
185:1990 animal births
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174:Categories
69:References
37:emphysema
47:See also
119:17 June
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110:(PDF)
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140:ISBN
121:2014
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