290:
195:
24:
442:
614:"Comparison of oral psoralen-UV-A with a portable tanning unit at home vs hospital-administered bath psoralen-UV-A in patients with chronic hand eczema: an open-label randomized controlled trial of efficacy"
401:
455:
653:
Thazhathveetil, AK; Liu, ST; Indig, FE; Seidman, MM (2007). "Psoralen conjugates for visualization of genomic interstrand cross-links localized by laser photoactivation".
339:
798:
910:
1004:
92:
1060:
486:
304:
1399:
462:
791:
247:
1169:
1021:
268:
690:"Synthesis and properties of photo-reactive antisense oligonucleotides containing 2'-O-psoralen-conjugated adenosine"
578:. UV/TMP generates small deletions (~1-3 Kbp), but all base transitions and transversions can also be obtained.
1394:
1009:
784:
190:
1053:
730:
549:
132:
1353:
36:
556:
and used to visualize sites of DNA damage. The compound is also being explored for development of
553:
545:
285:
58:
1358:
509:
594:
1046:
756:
711:
670:
635:
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362:
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68:
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112:
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1015:
751:
494:
433:
612:
Van
Coevorden, AM; Kamphof, WG; Van Sonderen, E; Bruynzeel, DP; Coenraads, PJ (2004).
552:
unless repaired by cellular mechanisms. In research it can be conjugated to dyes for
1388:
1368:
1343:
1338:
1096:
807:
183:
567:
sequence without affecting normal transcripts differing at even a single base pair.
905:
894:
811:
529:
422:
417:
412:
407:
776:
630:
613:
236:
1363:
1298:
1293:
1247:
1221:
958:
953:
878:
525:
313:
InChI=1S/C14H12O3/c1-7-4-12(15)17-14-9(3)13-10(6-11(7)14)5-8(2)16-13/h4-6H,1-3H3
570:
Trioxsalen (abbreviated as TMP) activated by UV-A exposure is commonly used in
323:
InChI=1/C14H12O3/c1-7-4-12(15)17-14-9(3)13-10(6-11(7)14)5-8(2)16-13/h4-6H,1-3H3
1322:
1127:
1086:
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920:
915:
847:
385:
143:
742:
1348:
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1201:
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1117:
986:
963:
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855:
706:
689:
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674:
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1373:
1211:
1206:
1164:
1149:
1112:
1078:
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973:
865:
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571:
533:
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498:
163:
172:
1272:
1216:
1159:
1091:
575:
513:
223:
23:
666:
1154:
1122:
1038:
688:
Higuchi, M; Yamayoshi, A; Kobori, A; Yamaoka, T; Murakami, A (2005).
537:
123:
432:
Except where otherwise noted, data are given for materials in their
211:
517:
103:
91:
81:
564:
521:
202:
1042:
780:
833:
273:
501:
derivative. It is obtained from several plants, mainly
450:
1331:
1315:
1281:
1265:
1230:
1194:
1185:
1178:
1140:
1105:
1077:
972:
946:
939:
887:
864:
846:
826:
819:
563:that can be cross-linked specifically to a mutant
735:WormBook: The Online Review of C. Elegans Biology
235:
731:"Forward and reverse mutagenesis in C. elegans"
67:
1054:
792:
8:
1227:
1191:
1182:
1102:
1061:
1047:
1039:
943:
823:
799:
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777:
288:
193:
151:
15:
750:
705:
629:
255:
729:Kutscher, Lena M.; Shaham, Shai (2014).
512:of the skin. It is administered either
586:
344:
309:
284:
171:
184:
316:Key: FMHHVULEAZTJMA-UHFFFAOYSA-N
131:
111:
7:
421:
411:
326:Key: FMHHVULEAZTJMA-UHFFFAOYAF
226:
210:
508:. Like other psoralens it causes
347:Cc1cc2c(o1)c(C)c1c(c2)c(C)cc(=O)o1
14:
1282:Meroterpene furanocoumarin ether
1170:Umbelliferone 7-apiosylglucoside
440:
22:
595:"Trioxsalen - Compound Summary"
436:(at 25 °C , 100 kPa).
694:Nucleic Acids Symposium Series
1:
631:10.1001/archderm.140.12.1463
574:research as an experimental
524:(the least damaging form of
1416:
911:Calcipotriol/betamethasone
1266:Furanocoumarin glycosides
999:
430:
394:
355:
335:
300:
51:
35:
30:
21:
808:Drugs used for psoriasis
743:10.1895/wormbook.1.167.1
548:in DNA, which can cause
618:Archives of Dermatology
546:interstrand cross-links
479:trimethylpsoralen (TMP)
390:228.24328
1400:O-methylated coumarins
655:Bioconjugate Chemistry
707:10.1093/nass/49.1.331
550:programmed cell death
45:-furobenzopyran-7-one
1354:Ethyl biscoumacetate
520:in conjunction with
37:Preferred IUPAC name
554:confocal microscopy
18:
1359:4-Hydroxycoumarins
1026:Never to phase III
510:photosensitization
463:Infobox references
16:
1382:
1381:
1311:
1310:
1307:
1306:
1261:
1260:
1136:
1135:
1036:
1035:
995:
994:
935:
934:
667:10.1021/bc060309t
471:Chemical compound
469:
468:
269:CompTox Dashboard
93:Interactive image
41:2,5,9-Trimethyl-7
1407:
1228:
1192:
1183:
1103:
1063:
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1049:
1040:
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772:
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561:oligonucleotides
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447:
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363:Chemical formula
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115:
95:
71:
26:
19:
1415:
1414:
1410:
1409:
1408:
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1405:
1404:
1395:Furanocoumarins
1385:
1384:
1383:
1378:
1327:
1303:
1277:
1257:
1226:
1187:Furanocoumarins
1174:
1132:
1101:
1073:
1067:
1037:
1032:
1031:
1016:Clinical trials
991:
968:
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883:
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805:
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723:
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542:photoactivation
472:
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459:
458: ?)
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365:
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12:
11:
5:
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1243:Isopimpinellin
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773:
721:
680:
645:
624:(12): 1463–6.
604:
585:
583:
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495:furanocoumarin
470:
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466:
461:
439:
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434:standard state
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1369:Phenprocoumon
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1357:
1355:
1352:
1350:
1347:
1345:
1344:Coumatetralyl
1342:
1340:
1339:Acenocoumarol
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1119:
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1110:
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1098:
1097:Umbelliferone
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758:
753:
748:
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736:
732:
725:
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717:
713:
708:
703:
700:(49): 331–2.
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532:treatment of
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395:Pharmacology
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341:
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286:DTXSID3023716
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185:ECHA InfoCard
182:
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56:
55:
50:
44:
38:
34:
29:
25:
20:
1252:
1231:O-Methylated
1106:O-Methylated
906:Calcipotriol
899:
895:Fumaric acid
873:
764:. Retrieved
734:
724:
697:
693:
683:
661:(2): 431–7.
658:
654:
648:
621:
617:
607:
598:
589:
569:
530:phototherapy
502:
490:
482:
478:
474:
473:
52:Identifiers
42:
1364:Hymecromone
1299:Imperatorin
1294:Bergamottin
1248:Methoxsalen
1222:Xanthotoxol
1179:Derivatives
1012:from market
959:Methoxsalen
954:Trioxysalen
879:Methoxsalen
874:Trioxysalen
544:it creates
528:light) for
526:ultraviolet
506:corylifolia
483:trioxysalen
356:Properties
191:100.021.327
113:CHEBI:28329
17:Trioxsalen
1389:Categories
1323:Dicoumarol
1253:Trioxsalen
1142:Glycosides
1128:Scopoletin
1087:Aesculetin
982:Etretinate
927:Tazarotene
921:Tacalcitol
916:Calcitriol
582:References
491:Trisoralen
475:Trioxsalen
386:Molar mass
257:Y6UY8OV51T
144:ChemSpider
133:ChEMBL1475
80:3D model (
59:CAS Number
1349:Ensaculin
1332:Synthetic
1316:Oligomers
1289:Auraptene
1238:Bergapten
1202:Angelicin
1195:Aglycones
1118:Herniarin
1079:Aglycones
1071:coumarins
1069:Types of
1022:Phase III
1010:Withdrawn
987:Acitretin
974:Retinoids
964:Bergapten
947:Psoralens
901:vitamin D
866:Psoralens
856:Dithranol
848:Antracens
558:antisense
540:. After
536:and hand
514:topically
69:3902-71-4
1374:Warfarin
1212:Psoralen
1207:Marmesin
1165:Scopolin
1150:Aesculin
1113:Fraxetin
940:Systemic
838:Coal tar
761:24449699
737:: 1–26.
716:17150768
675:17373769
640:15611423
572:genetics
534:vitiligo
504:Psoralea
499:psoralen
402:ATC code
164:DrugBank
1273:Apterin
1217:Vaginol
1160:Skimmin
1092:Ferujol
820:Topical
766:18 June
752:4078664
599:PubChem
576:mutagen
493:) is a
456:what is
454: (
420: (
418:D05BA01
416:)
410: (
408:D05AD01
380:
224:PubChem
173:DB04571
1155:Fraxin
1123:Osthol
1005:WHO-EM
759:
749:
714:
673:
638:
538:eczema
518:orally
497:and a
451:verify
448:
340:SMILES
212:D01034
124:ChEMBL
31:Names
888:Other
489:) or
305:InChI
104:ChEBI
82:JSmol
827:Tars
768:2021
757:PMID
712:PMID
671:PMID
636:PMID
565:mRNA
522:UV-A
248:UNII
237:5585
203:KEGG
153:5383
834:Tar
812:D05
747:PMC
739:doi
702:doi
663:doi
626:doi
622:140
516:or
487:INN
423:WHO
413:WHO
274:EPA
227:CID
1391::
1018::
836:/
755:.
745:.
733:.
710:.
698:49
696:.
692:.
669:.
659:18
657:.
634:.
620:.
616:.
597:.
481:,
426:)
374:12
370:14
1062:e
1055:t
1048:v
923:)
904:(
814:)
810:(
800:e
793:t
786:v
770:.
741::
718:.
704::
677:.
665::
642:.
628::
601:.
485:(
477:(
446:N
378:3
376:O
372:H
368:C
276:)
272:(
84:)
43:H
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
