Knowledge (XXG)

Triptonide

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Chang, Zongliang; Qin, Weibing; Zheng, Huili; Schegg, Kathleen; Han, Lu; Liu, Xiaohua; Wang, Yue; Wang, Zhuqing; McSwiggin, Hayden; Peng, Hongying; Yuan, Shuiqiao; Wu, Jiabao; Wang, Yongxia; Zhu, Shenghui; Jiang, Yanjia; Nie, Hua; Tang, Yuan; Zhou, Yu; Hitchcock, Michael J. M.; Tang, Yunge; Yan, Wei
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InChI=1S/C20H22O6/c1-8(2)18-13(25-18)14-20(26-14)17(3)5-4-9-10(7-23-15(9)21)11(17)6-12-19(20,24-12)16(18)22/h8,11-14H,4-7H2,1-3H3/t11-,12-,13-,14-,17-,18-,19+,20+/m0/s1
536: 263: 414: 529: 238: 585: 555: 522: 335: 575: 357: 352: 22: 179: 360:. A 2021 trial in mice and monkeys suggested that triptonide may offer a reversible male contraceptive. 49: 446: 105: 435:"Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates" 570: 565: 474: 506: 580: 502: 464: 454: 286: 199: 115: 415:"Male Birth Control Pill: Natural Compound Discovered With "Ideal" Contraceptive Effects" 159: 450: 469: 434: 329: 549: 395: 377: 224: 494: 459: 85:)-1-methyl-7-propan-2-yl-3,6,10,16-tetraoxaheptacycloicos-14(18)-ene-8,17-dione 314: 190: 17: 478: 211: 36: 170: 328:
Except where otherwise noted, data are given for materials in their
150: 138: 128: 510: 93:Triptonide; NSC 165677; 14-deoxy-14-oxo-triptolide 223: 271:CC(C)12(O1)34(O3)5(CCC6=C(5C74(C2=O)O7)COC6=O)C 114: 530: 8: 561:Heterocyclic compounds with 7 or more rings 537: 523: 413:Institute, The Lundquist (April 1, 2022). 198: 28: 468: 458: 369: 268: 243: 250:Key: SWOVVKGLGOOUKI-ZHGGVEMFSA-N 178: 158: 7: 491: 489: 214: 509:. You can help Knowledge (XXG) by 14: 493: 350:is a chemical compound found in 298: 35: 332:(at 25 °C , 100 kPa). 304: 292: 1: 358:traditional Chinese medicine 602: 488: 460:10.1038/s41467-021-21517-5 15: 326: 279: 259: 234: 98: 90: 48: 43: 34: 382:pubchem.ncbi.nlm.nih.gov 20:, another derivative of 16:Not to be confused with 586:Contraception for males 556:Organic compound stubs 501:This article about an 353:Tripterygium wilfordii 23:Tripterygium wilfordii 439:Nature Communications 576:Isopropyl compounds 451:2021NatCo..12.1253C 322: g·mol 31: 396:"Thunder God Vine" 356:, a plant used in 336:Infobox references 29: 518: 517: 433:(December 2021). 344:Chemical compound 342: 341: 140:Interactive image 593: 539: 532: 525: 503:organic compound 497: 490: 483: 482: 472: 462: 429: 423: 422: 410: 404: 403: 392: 386: 385: 374: 321: 306: 300: 294: 287:Chemical formula 227: 216: 202: 182: 162: 142: 118: 39: 32: 601: 600: 596: 595: 594: 592: 591: 590: 546: 545: 544: 543: 487: 486: 431: 430: 426: 412: 411: 407: 394: 393: 389: 376: 375: 371: 366: 345: 338: 333: 319: 309: 303: 297: 289: 275: 272: 267: 266: 255: 252: 251: 248: 242: 241: 230: 217: 205: 185: 165: 145: 132: 121: 108: 94: 86: 27: 12: 11: 5: 599: 597: 589: 588: 583: 578: 573: 568: 563: 558: 548: 547: 542: 541: 534: 527: 519: 516: 515: 498: 485: 484: 424: 405: 387: 368: 367: 365: 362: 343: 340: 339: 334: 330:standard state 327: 324: 323: 317: 311: 310: 307: 301: 295: 290: 285: 282: 281: 277: 276: 274: 273: 270: 262: 261: 260: 257: 256: 254: 253: 249: 246: 245: 237: 236: 235: 232: 231: 229: 228: 220: 218: 210: 207: 206: 204: 203: 195: 193: 187: 186: 184: 183: 175: 173: 167: 166: 164: 163: 155: 153: 147: 146: 144: 143: 135: 133: 126: 123: 122: 120: 119: 111: 109: 104: 101: 100: 96: 95: 92: 88: 87: 52: 46: 45: 41: 40: 13: 10: 9: 6: 4: 3: 2: 598: 587: 584: 582: 579: 577: 574: 572: 569: 567: 564: 562: 559: 557: 554: 553: 551: 540: 535: 533: 528: 526: 521: 520: 514: 512: 508: 504: 499: 496: 492: 480: 476: 471: 466: 461: 456: 452: 448: 444: 440: 436: 428: 425: 420: 416: 409: 406: 401: 397: 391: 388: 383: 379: 373: 370: 363: 361: 359: 355: 354: 349: 337: 331: 325: 318: 316: 313: 312: 291: 288: 284: 283: 278: 269: 265: 258: 244: 240: 233: 226: 222: 221: 219: 213: 209: 208: 201: 197: 196: 194: 192: 189: 188: 181: 177: 176: 174: 172: 169: 168: 161: 157: 156: 154: 152: 149: 148: 141: 137: 136: 134: 130: 125: 124: 117: 113: 112: 110: 107: 103: 102: 97: 89: 84: 80: 76: 72: 68: 64: 60: 56: 51: 47: 42: 38: 33: 25: 24: 19: 511:expanding it 500: 442: 438: 427: 419:SciTechDaily 418: 408: 399: 390: 381: 378:"Triptonide" 372: 351: 347: 346: 180:ChEMBL205190 160:CHEBI:132267 99:Identifiers 91:Other names 82: 78: 74: 70: 66: 62: 58: 54: 21: 445:(1): 1253. 280:Properties 30:Triptonide 550:Categories 364:References 348:Triptonide 315:Molar mass 191:ChemSpider 127:3D model ( 116:38647-11-9 106:CAS Number 50:IUPAC name 18:Triptolide 571:Lactones 566:Epoxides 479:33623031 581:Ketones 470:7902613 447:Bibcode 320:358.390 212:PubChem 477:  467:  264:SMILES 171:ChEMBL 44:Names 505:is a 400:NCCIH 239:InChI 225:65411 200:58875 151:ChEBI 129:JSmol 507:stub 475:PMID 465:PMC 455:doi 215:CID 81:,13 77:,11 552:: 473:. 463:. 453:. 443:12 441:. 437:. 417:. 398:. 380:. 302:22 296:20 73:,9 69:,7 65:,5 61:,4 57:,2 53:(1 538:e 531:t 524:v 513:. 481:. 457:: 449:: 421:. 402:. 384:. 308:6 305:O 299:H 293:C 131:) 83:S 79:S 75:S 71:S 67:S 63:S 59:S 55:S 26:.

Index

Triptolide
Tripterygium wilfordii

IUPAC name
CAS Number
38647-11-9
JSmol
Interactive image
ChEBI
CHEBI:132267
ChEMBL
ChEMBL205190
ChemSpider
58875
PubChem
65411
InChI
SMILES
Chemical formula
Molar mass
standard state
Infobox references
Tripterygium wilfordii
traditional Chinese medicine
"Triptonide"
"Thunder God Vine"
"Male Birth Control Pill: Natural Compound Discovered With "Ideal" Contraceptive Effects"
"Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates"
Bibcode
2021NatCo..12.1253C

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