Knowledge (XXG)

UBR4

Source 📝

1125:
Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S (Dec 2003).
242: 219: 116: 141: 500: 493: 248: 147: 1639: 1124:
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M,
255: 154: 1168:"Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro" 753: 734: 77: 1708: 1684: 1106: 1088: 1703: 241: 960: 953: 1275:
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction".
218: 1256: 1437:"Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600" 1075: 1054: 1071: 140: 115: 1050: 57: 254: 153: 1677: 247: 146: 798: 65: 779: 1670: 1546: 1448: 1395: 129: 44: 1209:"A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons" 936: 889: 1207:
Tasaki T, Mulder LC, Iwamatsu A, Lee MJ, Davydov IV, Varshavsky A, Muesing M, Kwon YT (Aug 2005).
89: 1384:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" 915: 868: 1617: 1574: 1521: 1476: 1423: 1370: 1335: 1292: 1238: 1189: 1148: 37: 1654: 1607: 1599: 1564: 1554: 1535:"The response of autologous T cells to a human melanoma is dominated by mutated neoantigens" 1511: 1501: 1466: 1456: 1413: 1403: 1360: 1325: 1317: 1284: 1228: 1220: 1179: 1138: 334: 265: 209: 164: 499: 492: 309: 85: 1550: 1452: 1399: 1612: 1587: 1569: 1534: 1516: 1489: 1471: 1436: 1233: 1208: 1418: 1383: 1349:"Characterization of cDNA clones in size-fractionated cDNA libraries from human brain" 1330: 1305: 668: 663: 658: 653: 637: 632: 627: 622: 617: 612: 607: 602: 597: 592: 587: 582: 566: 561: 556: 551: 546: 541: 1697: 1224: 528: 69: 1650: 327: 106: 93: 1588:"Large-scale mapping of human protein-protein interactions by mass spectrometry" 1111:
National Center for Biotechnology Information, U.S. National Library of Medicine
1093:
National Center for Biotechnology Information, U.S. National Library of Medicine
410: 1490:"p600, a unique protein required for membrane morphogenesis and cell survival" 226: 123: 73: 1365: 1348: 1559: 1506: 1461: 1184: 1167: 1127:"Complete sequencing and characterization of 21,243 full-length human cDNAs" 698: 470: 348: 293: 280: 192: 179: 81: 1621: 1578: 1525: 1480: 1427: 1408: 1288: 1242: 1193: 1152: 1374: 1339: 1296: 1000: 995: 48:, RBAF600, ZUBR1, p600, ubiquitin protein ligase E3 component n-recognin 4 984: 843: 824: 1603: 1321: 810: 765: 1016: 968: 720: 1638: 1143: 1126: 1166:
Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O (Apr 2000).
683: 679: 1646: 1023: 508: 61: 1382:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
317: 1658: 1488:
Nakatani Y, Konishi H, Vassilev A, et al. (2005).
1533:
Lennerz V, Fatho M, Gentilini C, et al. (2005).
482: 929: 908: 882: 861: 445:
dentate gyrus of hippocampal formation granule cell
1304:Yu W, Andersson B, Worley KC, et al. (1997). 1067: 1065: 1063: 1046: 1044: 1042: 264: 163: 1586:Ewing RM, Chu P, Elisma F, et al. (2007). 1435:Huh KW, DeMasi J, Ogawa H, et al. (2005). 1347:Seki N, Ohira M, Nagase T, et al. (1998). 16:Protein-coding gene in the species Homo sapiens 1072:GRCm38: Ensembl release 89: ENSMUSG00000066036 1678: 1257:"Entrez Gene: ZUBR1 zinc finger, UBR1 type 1" 669:ubiquitin-dependent protein catabolic process 8: 1306:"Large-scale concatenation cDNA sequencing" 1051:GRCh38: Ensembl release 89: ENSG00000127481 1685: 1671: 694: 524: 305: 204: 101: 1611: 1568: 1558: 1515: 1505: 1470: 1460: 1417: 1407: 1364: 1329: 1232: 1183: 1142: 1038: 562:ubiquitin-protein transferase activity 18: 269: 230: 225: 168: 127: 122: 7: 1635: 1633: 1657:. You can help Knowledge (XXG) by 926: 905: 879: 858: 834: 815: 789: 770: 744: 725: 487: 457:choroid plexus of fourth ventricle 405: 343: 322: 14: 1019:that in humans is encoded by the 1637: 1225:10.1128/MCB.25.16.7120-7136.2005 1013:E3 ubiquitin-protein ligase UBR4 498: 491: 253: 246: 240: 217: 152: 145: 139: 114: 638:ficolin-1-rich granule membrane 583:integral component of membrane 509:More reference expression data 471:More reference expression data 1: 1709:Human chromosome 1 gene stubs 238: 137: 1539:Proc. Natl. Acad. Sci. U.S.A 1494:Proc. Natl. Acad. Sci. U.S.A 1441:Proc. Natl. Acad. Sci. U.S.A 1388:Proc. Natl. Acad. Sci. U.S.A 1704:Genes on human chromosome 1 383:stromal cell of endometrium 1725: 1632: 1107:"Mouse PubMed Reference:" 1089:"Human PubMed Reference:" 999: 994: 990: 983: 967: 961:Chr 4: 139.08 – 139.22 Mb 948: 933: 912: 901: 886: 865: 854: 841: 837: 822: 818: 809: 796: 792: 777: 773: 764: 751: 747: 732: 728: 719: 704: 697: 693: 677: 633:tertiary granule membrane 628:specific granule membrane 527: 523: 506: 490: 481: 468: 417: 408: 355: 346: 316: 308: 304: 287: 274: 237: 216: 207: 203: 186: 173: 136: 113: 104: 100: 55: 52: 42: 35: 30: 26: 21: 664:neutrophil degranulation 1560:10.1073/pnas.0500090102 1507:10.1073/pnas.0507458102 1462:10.1073/pnas.0505337102 954:Chr 1: 19.07 – 19.21 Mb 1409:10.1073/pnas.242603899 1366:10.1093/dnares/4.5.345 1289:10.1006/abio.1996.0138 659:protein ubiquitination 449:superior frontal gyrus 441:neural layer of retina 1185:10.1093/dnares/7.1.65 567:transferase activity 232:Chromosome 4 (mouse) 130:Chromosome 1 (human) 1551:2005PNAS..10216013L 1545:(44): 16013–16018. 1500:(42): 15093–15098. 1453:2005PNAS..10211492H 1447:(32): 11492–11497. 1400:2002PNAS...9916899M 1394:(26): 16899–16903. 1645:This article on a 1604:10.1038/msb4100134 1322:10.1101/gr.7.4.353 799:ENSMUSG00000066036 647:Biological process 576:Cellular component 557:calmodulin binding 535:Molecular function 379:anterior pituitary 1666: 1665: 1219:(16): 7120–7136. 1010: 1009: 1006: 1005: 979: 978: 944: 943: 923: 922: 897: 896: 876: 875: 850: 849: 831: 830: 805: 804: 786: 785: 760: 759: 741: 740: 689: 688: 552:metal ion binding 519: 518: 515: 514: 477: 476: 464: 463: 429:lactiferous gland 425:perirhinal cortex 421:entorhinal cortex 402: 401: 300: 299: 199: 198: 1716: 1687: 1680: 1673: 1641: 1634: 1625: 1615: 1582: 1572: 1562: 1529: 1519: 1509: 1484: 1474: 1464: 1431: 1421: 1411: 1378: 1368: 1343: 1333: 1300: 1261: 1260: 1253: 1247: 1246: 1236: 1204: 1198: 1197: 1187: 1163: 1157: 1156: 1146: 1121: 1115: 1114: 1103: 1097: 1096: 1085: 1079: 1069: 1058: 1048: 992: 991: 963: 956: 939: 927: 918: 906: 902:RefSeq (protein) 892: 880: 871: 859: 835: 816: 790: 771: 745: 726: 695: 542:zinc ion binding 525: 511: 502: 495: 488: 473: 453:ventricular zone 413: 411:Top expressed in 406: 351: 349:Top expressed in 344: 323: 306: 296: 283: 272: 257: 250: 244: 233: 221: 205: 195: 182: 171: 156: 149: 143: 132: 118: 102: 96: 94:UBR4 - orthologs 47: 40: 19: 1724: 1723: 1719: 1718: 1717: 1715: 1714: 1713: 1694: 1693: 1692: 1691: 1630: 1628: 1592:Mol. Syst. Biol 1585: 1532: 1487: 1434: 1381: 1346: 1303: 1274: 1270: 1268:Further reading 1265: 1264: 1255: 1254: 1250: 1206: 1205: 1201: 1165: 1164: 1160: 1123: 1122: 1118: 1105: 1104: 1100: 1087: 1086: 1082: 1070: 1061: 1049: 1040: 1035: 1029: 1001:View/Edit Mouse 996:View/Edit Human 959: 952: 949:Location (UCSC) 935: 914: 888: 867: 780:ENSG00000127481 673: 642: 623:plasma membrane 571: 547:protein binding 507: 497: 496: 469: 460: 455: 451: 447: 443: 439: 437:muscle of thigh 435: 431: 427: 423: 409: 398: 393: 389: 385: 381: 377: 373: 369: 365: 363:skin of abdomen 361: 347: 291: 278: 270: 260: 259: 258: 251: 231: 208:Gene location ( 190: 177: 169: 159: 158: 157: 150: 128: 105:Gene location ( 56: 43: 36: 17: 12: 11: 5: 1722: 1720: 1712: 1711: 1706: 1696: 1695: 1690: 1689: 1682: 1675: 1667: 1664: 1663: 1642: 1627: 1626: 1583: 1530: 1485: 1432: 1379: 1359:(5): 345–349. 1344: 1301: 1283:(1): 107–113. 1271: 1269: 1266: 1263: 1262: 1248: 1199: 1158: 1144:10.1038/ng1285 1116: 1098: 1080: 1059: 1037: 1036: 1034: 1031: 1008: 1007: 1004: 1003: 998: 988: 987: 981: 980: 977: 976: 974: 972: 965: 964: 957: 950: 946: 945: 942: 941: 931: 930: 924: 921: 920: 910: 909: 903: 899: 898: 895: 894: 884: 883: 877: 874: 873: 863: 862: 856: 852: 851: 848: 847: 839: 838: 832: 829: 828: 820: 819: 813: 807: 806: 803: 802: 794: 793: 787: 784: 783: 775: 774: 768: 762: 761: 758: 757: 749: 748: 742: 739: 738: 730: 729: 723: 717: 716: 711: 706: 702: 701: 691: 690: 687: 686: 675: 674: 672: 671: 666: 661: 656: 650: 648: 644: 643: 641: 640: 635: 630: 625: 620: 615: 610: 605: 600: 595: 590: 585: 579: 577: 573: 572: 570: 569: 564: 559: 554: 549: 544: 538: 536: 532: 531: 521: 520: 517: 516: 513: 512: 504: 503: 485: 479: 478: 475: 474: 466: 465: 462: 461: 459: 458: 454: 450: 446: 442: 438: 434: 430: 426: 422: 418: 415: 414: 403: 400: 399: 397: 396: 392: 388: 384: 380: 376: 375:gastric mucosa 372: 368: 364: 360: 356: 353: 352: 340: 339: 331: 320: 314: 313: 310:RNA expression 302: 301: 298: 297: 289: 285: 284: 276: 273: 268: 262: 261: 252: 245: 239: 235: 234: 229: 223: 222: 214: 213: 201: 200: 197: 196: 188: 184: 183: 175: 172: 167: 161: 160: 151: 144: 138: 134: 133: 126: 120: 119: 111: 110: 98: 97: 54: 50: 49: 41: 33: 32: 28: 27: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 1721: 1710: 1707: 1705: 1702: 1701: 1699: 1688: 1683: 1681: 1676: 1674: 1669: 1668: 1662: 1660: 1656: 1652: 1648: 1643: 1640: 1636: 1631: 1623: 1619: 1614: 1609: 1605: 1601: 1597: 1593: 1589: 1584: 1580: 1576: 1571: 1566: 1561: 1556: 1552: 1548: 1544: 1540: 1536: 1531: 1527: 1523: 1518: 1513: 1508: 1503: 1499: 1495: 1491: 1486: 1482: 1478: 1473: 1468: 1463: 1458: 1454: 1450: 1446: 1442: 1438: 1433: 1429: 1425: 1420: 1415: 1410: 1405: 1401: 1397: 1393: 1389: 1385: 1380: 1376: 1372: 1367: 1362: 1358: 1354: 1350: 1345: 1341: 1337: 1332: 1327: 1323: 1319: 1315: 1311: 1307: 1302: 1298: 1294: 1290: 1286: 1282: 1278: 1277:Anal. Biochem 1273: 1272: 1267: 1258: 1252: 1249: 1244: 1240: 1235: 1230: 1226: 1222: 1218: 1214: 1213:Mol Cell Biol 1210: 1203: 1200: 1195: 1191: 1186: 1181: 1177: 1173: 1169: 1162: 1159: 1154: 1150: 1145: 1140: 1136: 1132: 1128: 1120: 1117: 1112: 1108: 1102: 1099: 1094: 1090: 1084: 1081: 1077: 1073: 1068: 1066: 1064: 1060: 1056: 1052: 1047: 1045: 1043: 1039: 1032: 1030: 1027: 1025: 1022: 1018: 1014: 1002: 997: 993: 989: 986: 982: 975: 973: 970: 966: 962: 958: 955: 951: 947: 940: 938: 932: 928: 925: 919: 917: 911: 907: 904: 900: 893: 891: 885: 881: 878: 872: 870: 864: 860: 857: 855:RefSeq (mRNA) 853: 846: 845: 840: 836: 833: 827: 826: 821: 817: 814: 812: 808: 801: 800: 795: 791: 788: 782: 781: 776: 772: 769: 767: 763: 756: 755: 750: 746: 743: 737: 736: 731: 727: 724: 722: 718: 715: 712: 710: 707: 703: 700: 696: 692: 685: 681: 676: 670: 667: 665: 662: 660: 657: 655: 654:viral process 652: 651: 649: 646: 645: 639: 636: 634: 631: 629: 626: 624: 621: 619: 616: 614: 611: 609: 606: 604: 601: 599: 596: 594: 591: 589: 586: 584: 581: 580: 578: 575: 574: 568: 565: 563: 560: 558: 555: 553: 550: 548: 545: 543: 540: 539: 537: 534: 533: 530: 529:Gene ontology 526: 522: 510: 505: 501: 494: 489: 486: 484: 480: 472: 467: 456: 452: 448: 444: 440: 436: 432: 428: 424: 420: 419: 416: 412: 407: 404: 394: 390: 387:apex of heart 386: 382: 378: 374: 370: 366: 362: 358: 357: 354: 350: 345: 342: 341: 338: 336: 332: 330: 329: 325: 324: 321: 319: 315: 311: 307: 303: 295: 290: 286: 282: 277: 267: 263: 256: 249: 243: 236: 228: 224: 220: 215: 211: 206: 202: 194: 189: 185: 181: 176: 166: 162: 155: 148: 142: 135: 131: 125: 121: 117: 112: 108: 103: 99: 95: 91: 87: 83: 79: 75: 71: 67: 63: 59: 51: 46: 39: 34: 29: 25: 20: 1659:expanding it 1651:chromosome 1 1644: 1629: 1595: 1591: 1542: 1538: 1497: 1493: 1444: 1440: 1391: 1387: 1356: 1352: 1316:(4): 353–8. 1313: 1309: 1280: 1276: 1251: 1216: 1212: 1202: 1178:(1): 65–73. 1175: 1171: 1161: 1137:(1): 40–45. 1134: 1130: 1119: 1110: 1101: 1092: 1083: 1028: 1020: 1012: 1011: 937:NP_001153791 934: 913: 890:NM_001160319 887: 866: 842: 823: 797: 778: 752: 733: 713: 708: 593:cytoskeleton 367:right testis 333: 326: 292:139,216,899 279:139,079,920 53:External IDs 608:nucleoplasm 371:left testis 359:skin of leg 271:4|4 D3 191:19,210,266 178:19,074,510 31:Identifiers 1698:Categories 1310:Genome Res 1078:, May 2017 1057:, May 2017 1033:References 588:centrosome 395:left ovary 391:right lung 337:(ortholog) 74:HomoloGene 1649:on human 1598:(1): 89. 1131:Nat Genet 916:NP_065816 869:NM_020765 699:Orthologs 613:cytoplasm 433:CA3 field 82:GeneCards 1622:17353931 1579:16247014 1526:16214886 1481:16061792 1428:12477932 1243:16055722 1194:10718198 1153:14702039 1074:– 1053:– 985:Wikidata 678:Sources: 598:membrane 1613:1847948 1570:1266037 1547:Bibcode 1517:1247991 1472:1182135 1449:Bibcode 1396:Bibcode 1375:9455484 1353:DNA Res 1340:9110174 1297:8619474 1234:1190250 1172:DNA Res 1076:Ensembl 1055:Ensembl 811:UniProt 766:Ensembl 705:Species 684:QuickGO 618:cytosol 603:nucleus 312:pattern 170:1p36.13 70:1916366 38:Aliases 1620:  1610:  1577:  1567:  1524:  1514:  1479:  1469:  1426:  1419:139241 1416:  1373:  1338:  1331:139146 1328:  1295:  1241:  1231:  1192:  1151:  1017:enzyme 1015:is an 971:search 969:PubMed 844:A2AN08 825:Q5T4S7 721:Entrez 483:BioGPS 62:609890 1653:is a 754:69116 735:23352 714:Mouse 709:Human 680:Amigo 335:Mouse 328:Human 275:Start 210:Mouse 174:Start 107:Human 78:10804 1655:stub 1647:gene 1618:PMID 1575:PMID 1522:PMID 1477:PMID 1424:PMID 1371:PMID 1336:PMID 1293:PMID 1239:PMID 1190:PMID 1149:PMID 1024:gene 1021:UBR4 318:Bgee 266:Band 227:Chr. 165:Band 124:Chr. 86:UBR4 58:OMIM 45:UBR4 22:UBR4 1608:PMC 1600:doi 1565:PMC 1555:doi 1543:102 1512:PMC 1502:doi 1498:102 1467:PMC 1457:doi 1445:102 1414:PMC 1404:doi 1361:doi 1326:PMC 1318:doi 1285:doi 1281:236 1229:PMC 1221:doi 1180:doi 1139:doi 288:End 187:End 90:OMA 66:MGI 1700:: 1616:. 1606:. 1594:. 1590:. 1573:. 1563:. 1553:. 1541:. 1537:. 1520:. 1510:. 1496:. 1492:. 1475:. 1465:. 1455:. 1443:. 1439:. 1422:. 1412:. 1402:. 1392:99 1390:. 1386:. 1369:. 1355:. 1351:. 1334:. 1324:. 1312:. 1308:. 1291:. 1279:. 1237:. 1227:. 1217:25 1215:. 1211:. 1188:. 1174:. 1170:. 1147:. 1135:36 1133:. 1129:. 1109:. 1091:. 1062:^ 1041:^ 1026:. 682:/ 294:bp 281:bp 193:bp 180:bp 88:; 84:: 80:; 76:: 72:; 68:: 64:; 60:: 1686:e 1679:t 1672:v 1661:. 1624:. 1602:: 1596:3 1581:. 1557:: 1549:: 1528:. 1504:: 1483:. 1459:: 1451:: 1430:. 1406:: 1398:: 1377:. 1363:: 1357:4 1342:. 1320:: 1314:7 1299:. 1287:: 1259:. 1245:. 1223:: 1196:. 1182:: 1176:7 1155:. 1141:: 1113:. 1095:. 212:) 109:) 92::

Index

Aliases
UBR4
OMIM
609890
MGI
1916366
HomoloGene
10804
GeneCards
UBR4
OMA
UBR4 - orthologs
Human
Chromosome 1 (human)
Chr.
Chromosome 1 (human)
Chromosome 1 (human)
Genomic location for UBR4
Genomic location for UBR4
Band
bp
bp
Mouse
Chromosome 4 (mouse)
Chr.
Chromosome 4 (mouse)
Genomic location for UBR4
Genomic location for UBR4
Band
bp

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