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VCAM-1

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cells can use VCAM-1 to adhere to the endothelium, VCAM-1 may participate in monocyte recruitment to atherosclerotic sites, and it is highly overexpressed in the inflamed brain. As a result, VCAM-1 is a potential
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Cybulsky M, Fries JW, Williams AJ, Sultan P, Eddy RL, Byers MG, Shows TB, Gimbrone MA Jr, Collins T (1991). "The human VCAM1 gene is assigned to chromosome 1p31-p32".
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VCAM-1 is also upregulated if vWF (Von Willebrand Factor) is given in knock-out (KO) ADMATS13 mice but not on mice without KO.
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Barreiro O, Yanez-Mo M, Serrador JM, Montoya MC, Vicente-Manzanares M, Tejedor R, Furthmayr H, Sanchez-Madrid F (Jun 2002).
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Upregulation of VCAM-1 in endothelial cells by cytokines occurs as a result of increased
1731: 1425:(nuclear factor-kappa B) sites. The sustained expression of VCAM-1 lasts over 24 hours. 3671: 3093: 2604: 2407: 1925: 1900: 1836: 1809: 1750: 1713: 1648: 1623: 1320: 44: 1671:
Le Besnerais M, Favre J, Denis CV, Mulder P, Martinet J, Nicol L, et al. (2016).
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National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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Proceedings of the National Academy of Sciences of the United States of America
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that encode different isoforms in humans. The gene product is a cell surface
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heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
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Eibl RH, Benoit M (2004). "Molecular resolution of cell adhesion forces".
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Yang ZX, Han ZB, Ji YR, Wang YW, Liang L, Chi Y, et al. (2013).
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cellular response to vascular endothelial growth factor stimulus
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alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex
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calcium-mediated signaling using intracellular calcium source
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Overview of all the structural information available in the
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CD106 also exists on the surface of some subpopulations of
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cell-cell adhesion in response to extracellular stimulus
401: 1606:"Entrez Gene: VCAM1 vascular cell adhesion molecule 1" 566: 132:, CD106, INCAM-100, vascular cell adhesion molecule 1 1350:, a type I membrane protein that is a member of the 4589: 4557: 4482: 4454: 4401: 4375: 4366: 4357: 4270: 4159: 4150: 3910: 3704: 3453: 3137: 2860: 2520: 2118: 1182: 1153: 1127: 1098: 1521: 1519: 1517: 1500: 1498: 1496: 1382:. It also functions in leukocyte-endothelial cell 1323:domains, and is expressed on both large and small 1866:"Targeting leukocyte integrins in human diseases" 348: 247: 1428:Primarily, the VCAM-1 protein is an endothelial 1386:, and it may play a role in the development of 16:Protein-coding gene in the species Homo sapiens 1617: 1615: 1526:GRCm38: Ensembl release 89: ENSMUSG00000027962 4124: 2087: 1996: 8: 1362:The VCAM-1 protein mediates the adhesion of 1505:GRCh38: Ensembl release 89: ENSG00000162692 816:positive regulation of T cell proliferation 766:interferon-gamma-mediated signaling pathway 4372: 4363: 4156: 4131: 4117: 4109: 2094: 2080: 2072: 2003: 1989: 1981: 1973:(Vascular cell adhesion protein 1) at the 931: 771:cellular response to tumor necrosis factor 601: 389: 288: 185: 79: 2111:list of human clusters of differentiation 1952:at the U.S. National Library of Medicine 1924: 1881: 1835: 1825: 1749: 1739: 1688: 1647: 1319:. The VCAM-1 gene contains six or seven 1311:, the superfamily of proteins including 2031:: Highly Hydrated Human VCAM-1 Fragment 2018: 1492: 34: 1409:(IL-1)) and through stabilization of 725:integral component of plasma membrane 353: 314: 309: 252: 211: 206: 7: 1417:(IL-4)). The promoter region of the 1775:IEE Proceedings - Nanobiotechnology 881:cytokine-mediated signaling pathway 1179: 1150: 1124: 1095: 1071: 1052: 1026: 1007: 981: 962: 571: 525:choroid plexus of fourth ventricle 489: 427: 406: 14: 1288:that in humans is encoded by the 1270:vascular cell adhesion molecule 1 906:cellular response to amyloid-beta 791:extracellular matrix organization 2051: 2036: 2021: 1421:gene contains functional tandem 1266:Vascular cell adhesion protein 1 715:external side of plasma membrane 575: 337: 330: 324: 301: 236: 229: 223: 198: 43: 1864:Yonekawa K, Harlan JM (2005). 1278:cluster of differentiation 106 896:cardiac neuron differentiation 886:heterotypic cell-cell adhesion 831:leukocyte tethering or rolling 801:response to lipopolysaccharide 746:response to ionizing radiation 645:integral component of membrane 629:cell adhesion molecule binding 619:primary amine oxidase activity 586:More reference expression data 555:More reference expression data 1: 1917:10.1158/0008-5472.CAN-07-1543 1444:). It has also been shown to 871:chronic inflammatory response 826:regulation of immune response 322: 221: 1808:Marcos-Contreras OA (2020). 1741:10.1371/journal.pone.0059354 821:membrane to membrane docking 741:leukocyte cell-cell adhesion 517:Epithelium of choroid plexus 4670:Genes on human chromosome 1 2107:clusters of differentiation 1403:tumor necrosis factor-alpha 811:acute inflammatory response 4691: 4597:Lymphocyte homing receptor 1309:immunoglobulin superfamily 1307:VCAM-1 is a member of the 25: 18: 2016: 1561:"Mouse PubMed Reference:" 1543:"Human PubMed Reference:" 1252: 1247: 1243: 1236: 1220: 1207:Chr 1: 100.72 – 100.74 Mb 1201: 1186: 1157: 1146: 1131: 1102: 1091: 1078: 1074: 1059: 1055: 1046: 1033: 1029: 1014: 1010: 1001: 988: 984: 969: 965: 956: 941: 934: 930: 914: 604: 600: 583: 574: 565: 552: 501: 492: 439: 430: 400: 392: 388: 371: 358: 321: 300: 291: 287: 270: 257: 220: 197: 188: 184: 139: 136: 126: 119: 114: 87: 82: 65: 60: 55: 51: 42: 37: 4629:Carcinoembryonic antigen 4483:Unconventional/ungrouped 1954:Medical Subject Headings 1331:cells are stimulated by 1295:. VCAM-1 functions as a 1214:Chr 3: 115.9 – 115.92 Mb 455:tendon of biceps brachii 4144:cell adhesion molecules 1827:10.1073/pnas.1912012117 1787:10.1049/ip-nbt:20040707 796:amine metabolic process 1464:mesenchymal stem cells 1401:(e.g., in response to 1297:cell adhesion molecule 841:B cell differentiation 471:metanephric glomerulus 4336:Glycoprotein IIb/IIIa 1640:10.1083/jcb.200112126 1580:Cytogenet. Cell Genet 1337:alternatively spliced 710:extracellular exosome 695:endoplasmic reticulum 505:stroma of bone marrow 4308:Macrophage-1 antigen 4294:Integrin alphaXbeta2 1392:rheumatoid arthritis 851:cell-matrix adhesion 786:response to zinc ion 776:response to nicotine 761:response to nutrient 355:3 G1|3 50.17 cM 316:Chromosome 3 (mouse) 214:Chromosome 1 (human) 83:List of PDB id codes 56:Available structures 4173:Myelin protein zero 4152:Calcium-independent 1883:10.1189/jlb.0804460 1732:2013PLoSO...859354Y 1442:smooth muscle cells 1384:signal transduction 861:response to ethanol 756:response to hypoxia 720:extracellular space 675:apical part of cell 1586:(3–4): 1850–1867. 1399:gene transcription 1036:ENSMUSG00000027962 876:cell-cell adhesion 734:Biological process 638:Cellular component 612:Molecular function 521:tibiofemoral joint 4657: 4656: 4585: 4584: 4553: 4552: 4359:Calcium-dependent 4353: 4352: 4140:Membrane proteins 4106: 4105: 2069: 2068: 1690:10.1111/jth.13439 1683:(10): 1917–1930. 1592:10.1159/000133735 1348:sialoglycoprotein 1263: 1262: 1259: 1258: 1232: 1231: 1197: 1196: 1176: 1175: 1142: 1141: 1121: 1120: 1087: 1086: 1068: 1067: 1042: 1041: 1023: 1022: 997: 996: 978: 977: 926: 925: 596: 595: 592: 591: 561: 560: 548: 547: 486: 485: 384: 383: 283: 282: 178:VCAM1 - orthologs 110: 109: 106: 105: 66:Ortholog search: 4682: 4373: 4364: 4157: 4133: 4126: 4119: 4110: 2096: 2089: 2082: 2073: 2055: 2040: 2025: 2005: 1998: 1991: 1982: 1938: 1928: 1895: 1885: 1850: 1849: 1839: 1829: 1820:(7): 3405–3414. 1805: 1799: 1798: 1770: 1764: 1763: 1753: 1743: 1709: 1703: 1702: 1692: 1677:J Thromb Haemost 1668: 1662: 1661: 1651: 1619: 1610: 1609: 1602: 1596: 1595: 1575: 1569: 1568: 1557: 1551: 1550: 1539: 1533: 1523: 1512: 1502: 1317:T-cell receptors 1245: 1244: 1216: 1209: 1192: 1180: 1171: 1151: 1147:RefSeq (protein) 1137: 1125: 1116: 1096: 1072: 1053: 1027: 1008: 982: 963: 932: 624:integrin binding 602: 588: 579: 572: 557: 497: 495:Top expressed in 490: 443:cartilage tissue 435: 433:Top expressed in 428: 407: 390: 380: 367: 356: 341: 334: 328: 317: 305: 289: 279: 266: 255: 240: 233: 227: 216: 202: 186: 180: 131: 124: 101: 80: 74: 53: 52: 47: 35: 4690: 4689: 4685: 4684: 4683: 4681: 4680: 4679: 4660: 4659: 4658: 4653: 4581: 4549: 4478: 4450: 4397: 4349: 4266: 4146: 4137: 4107: 4102: 3906: 3700: 3449: 3133: 2856: 2516: 2114: 2100: 2070: 2065: 2062: 2056: 2047: 2041: 2032: 2026: 2012: 2009: 1946: 1941: 1898: 1870:J. Leukoc. 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2244: 2239: 2234: 2224: 2219: 2214: 2213: 2212: 2202: 2197: 2192: 2187: 2182: 2181: 2180: 2175: 2170: 2160: 2155: 2154: 2153: 2148: 2143: 2138: 2133: 2122: 2120: 2116: 2115: 2101: 2099: 2098: 2091: 2084: 2076: 2067: 2066: 2064: 2063: 2057: 2050: 2048: 2042: 2035: 2033: 2027: 2020: 2017: 2014: 2013: 2010: 2008: 2007: 2000: 1993: 1985: 1979: 1978: 1957: 1945: 1944:External links 1942: 1940: 1939: 1911:(13): 6003–6. 1899:Wu TC (2007). 1896: 1860: 1858: 1855: 1852: 1851: 1800: 1765: 1704: 1663: 1634:(7): 1233–45. 1611: 1597: 1570: 1552: 1534: 1513: 1491: 1490: 1488: 1485: 1471: 1468: 1413:(mRNA) (e.g., 1359: 1356: 1352:Ig superfamily 1321:immunoglobulin 1304: 1301: 1268:also known as 1261: 1260: 1257: 1256: 1251: 1241: 1240: 1234: 1233: 1230: 1229: 1227: 1225: 1218: 1217: 1210: 1203: 1199: 1198: 1195: 1194: 1184: 1183: 1177: 1174: 1173: 1155: 1154: 1148: 1144: 1143: 1140: 1139: 1129: 1128: 1122: 1119: 1118: 1100: 1099: 1093: 1089: 1088: 1085: 1084: 1076: 1075: 1069: 1066: 1065: 1057: 1056: 1050: 1044: 1043: 1040: 1039: 1031: 1030: 1024: 1021: 1020: 1012: 1011: 1005: 999: 998: 995: 994: 986: 985: 979: 976: 975: 967: 966: 960: 954: 953: 948: 943: 939: 938: 928: 927: 924: 923: 912: 911: 909: 908: 903: 898: 893: 888: 883: 878: 873: 868: 863: 858: 853: 848: 843: 838: 833: 828: 823: 818: 813: 808: 803: 798: 793: 788: 783: 778: 773: 768: 763: 758: 753: 748: 743: 737: 735: 731: 730: 728: 727: 722: 717: 712: 707: 702: 697: 692: 690:early endosome 687: 682: 677: 672: 667: 662: 657: 652: 647: 641: 639: 635: 634: 632: 631: 626: 621: 615: 613: 609: 608: 598: 597: 594: 593: 590: 589: 581: 580: 569: 563: 562: 559: 558: 550: 549: 546: 545: 543: 542: 538: 534: 530: 529:left lung lobe 526: 522: 518: 514: 510: 506: 502: 499: 498: 487: 484: 483: 481: 480: 476: 475:synovial joint 472: 468: 464: 460: 456: 452: 448: 444: 440: 437: 436: 424: 423: 415: 404: 398: 397: 394:RNA expression 386: 385: 382: 381: 373: 369: 368: 360: 357: 352: 346: 345: 336: 329: 323: 319: 318: 313: 307: 306: 298: 297: 285: 284: 281: 280: 272: 268: 267: 259: 256: 251: 245: 244: 235: 228: 222: 218: 217: 210: 204: 203: 195: 194: 182: 181: 138: 134: 133: 125: 117: 116: 112: 111: 108: 107: 104: 103: 85: 84: 76: 75: 64: 58: 57: 49: 48: 40: 39: 15: 13: 10: 9: 6: 4: 3: 2: 4687: 4676: 4673: 4671: 4668: 4667: 4665: 4650: 4647: 4645: 4642: 4640: 4637: 4635: 4632: 4630: 4627: 4626: 4622: 4618: 4614: 4613: 4609: 4607: 4604: 4602: 4598: 4595: 4594: 4592: 4588: 4578: 4575: 4573: 4570: 4568: 4565: 4564: 4562: 4560: 4556: 4546: 4543: 4541: 4538: 4536: 4533: 4531: 4528: 4526: 4523: 4521: 4518: 4516: 4513: 4511: 4508: 4506: 4503: 4501: 4498: 4496: 4493: 4491: 4488: 4487: 4485: 4481: 4475: 4472: 4470: 4467: 4465: 4462: 4461: 4459: 4457: 4456:Protocadherin 4453: 4446: 4442: 4438: 4434: 4431: 4428: 4424: 4420: 4416: 4412: 4409: 4408: 4406: 4404: 4400: 4394: 4391: 4389: 4386: 4384: 4381: 4380: 4378: 4374: 4371: 4369: 4365: 4362: 4360: 4356: 4345: 4341: 4337: 4334: 4331: 4327: 4323: 4320: 4317: 4313: 4309: 4306: 4303: 4299: 4295: 4292: 4289: 4285: 4281: 4278: 4277: 4275: 4273: 4269: 4261: 4258: 4256: 4253: 4251: 4248: 4246: 4243: 4241: 4238: 4236: 4233: 4232: 4231: 4228: 4224: 4221: 4219: 4216: 4214: 4211: 4209: 4206: 4205: 4204: 4201: 4199: 4196: 4194: 4191: 4188: 4184: 4180: 4177: 4174: 4170: 4167: 4166: 4164: 4162: 4158: 4155: 4153: 4149: 4145: 4141: 4134: 4129: 4127: 4122: 4120: 4115: 4114: 4111: 4099: 4096: 4094: 4091: 4089: 4086: 4084: 4081: 4079: 4076: 4074: 4071: 4069: 4066: 4064: 4061: 4059: 4056: 4054: 4051: 4049: 4046: 4044: 4041: 4039: 4036: 4034: 4031: 4029: 4026: 4024: 4021: 4019: 4016: 4014: 4011: 4009: 4006: 4004: 4001: 3999: 3996: 3994: 3991: 3989: 3986: 3984: 3981: 3979: 3976: 3974: 3971: 3969: 3966: 3964: 3961: 3959: 3956: 3954: 3951: 3949: 3946: 3944: 3941: 3939: 3936: 3934: 3931: 3929: 3926: 3924: 3921: 3919: 3916: 3915: 3913: 3909: 3903: 3900: 3898: 3895: 3893: 3890: 3888: 3885: 3883: 3880: 3878: 3875: 3873: 3870: 3868: 3865: 3863: 3860: 3858: 3855: 3853: 3850: 3848: 3845: 3843: 3840: 3838: 3835: 3833: 3830: 3828: 3825: 3823: 3820: 3818: 3815: 3813: 3810: 3808: 3805: 3803: 3800: 3798: 3795: 3793: 3790: 3788: 3785: 3783: 3780: 3778: 3775: 3773: 3770: 3768: 3765: 3763: 3760: 3758: 3755: 3753: 3750: 3748: 3745: 3743: 3740: 3738: 3735: 3733: 3730: 3728: 3725: 3723: 3720: 3718: 3715: 3713: 3710: 3709: 3707: 3703: 3697: 3694: 3692: 3688: 3685: 3683: 3680: 3678: 3675: 3673: 3670: 3668: 3665: 3663: 3660: 3658: 3655: 3653: 3650: 3648: 3645: 3643: 3640: 3636: 3633: 3631: 3628: 3627: 3626: 3623: 3621: 3618: 3616: 3613: 3611: 3608: 3606: 3603: 3601: 3598: 3596: 3593: 3591: 3588: 3586: 3583: 3581: 3578: 3576: 3573: 3571: 3568: 3566: 3563: 3561: 3558: 3555: 3552: 3550: 3546: 3543: 3541: 3538: 3534: 3531: 3529: 3526: 3525: 3524: 3521: 3519: 3516: 3512: 3509: 3507: 3504: 3503: 3502: 3499: 3497: 3494: 3492: 3489: 3487: 3484: 3482: 3479: 3477: 3474: 3472: 3469: 3467: 3464: 3462: 3459: 3458: 3456: 3452: 3446: 3443: 3441: 3438: 3436: 3433: 3431: 3428: 3426: 3423: 3421: 3418: 3416: 3413: 3411: 3408: 3406: 3403: 3401: 3398: 3396: 3393: 3391: 3388: 3386: 3383: 3381: 3378: 3376: 3373: 3371: 3368: 3366: 3363: 3359: 3356: 3354: 3351: 3350: 3349: 3346: 3344: 3341: 3339: 3336: 3334: 3331: 3327: 3324: 3322: 3319: 3317: 3314: 3313: 3312: 3309: 3307: 3304: 3302: 3299: 3297: 3294: 3292: 3289: 3285: 3282: 3280: 3277: 3276: 3275: 3272: 3270: 3267: 3265: 3262: 3260: 3257: 3255: 3252: 3250: 3247: 3245: 3242: 3238: 3235: 3233: 3230: 3229: 3228: 3225: 3222: 3219: 3217: 3214: 3212: 3209: 3207: 3204: 3202: 3198: 3195: 3193: 3190: 3186: 3183: 3181: 3178: 3176: 3173: 3172: 3171: 3168: 3166: 3163: 3161: 3158: 3156: 3153: 3151: 3148: 3146: 3143: 3142: 3140: 3136: 3130: 3127: 3125: 3122: 3120: 3117: 3115: 3112: 3110: 3107: 3105: 3102: 3100: 3097: 3095: 3092: 3090: 3087: 3085: 3082: 3080: 3077: 3075: 3072: 3070: 3067: 3065: 3062: 3060: 3057: 3055: 3052: 3050: 3047: 3045: 3042: 3040: 3037: 3035: 3032: 3030: 3027: 3025: 3022: 3020: 3017: 3015: 3012: 3010: 3007: 3003: 3000: 2998: 2995: 2994: 2993: 2990: 2986: 2983: 2981: 2978: 2977: 2976: 2973: 2971: 2968: 2966: 2963: 2961: 2958: 2956: 2953: 2951: 2948: 2946: 2943: 2941: 2938: 2936: 2933: 2931: 2928: 2926: 2923: 2921: 2918: 2916: 2913: 2909: 2906: 2904: 2901: 2900: 2899: 2896: 2894: 2891: 2889: 2886: 2884: 2881: 2879: 2876: 2874: 2871: 2869: 2866: 2865: 2863: 2859: 2853: 2850: 2848: 2845: 2843: 2840: 2838: 2835: 2833: 2830: 2828: 2825: 2823: 2820: 2818: 2815: 2813: 2809: 2806: 2804: 2801: 2799: 2796: 2794: 2791: 2789: 2786: 2784: 2781: 2777: 2774: 2772: 2769: 2767: 2764: 2762: 2759: 2757: 2754: 2752: 2749: 2748: 2747: 2744: 2742: 2739: 2737: 2734: 2732: 2729: 2727: 2724: 2722: 2719: 2715: 2712: 2710: 2707: 2706: 2705: 2702: 2700: 2697: 2695: 2692: 2690: 2687: 2685: 2682: 2680: 2677: 2675: 2672: 2670: 2667: 2665: 2662: 2658: 2655: 2653: 2650: 2648: 2645: 2643: 2640: 2638: 2635: 2633: 2630: 2629: 2628: 2625: 2621: 2618: 2616: 2613: 2611: 2608: 2607: 2606: 2603: 2601: 2598: 2594: 2591: 2589: 2586: 2584: 2581: 2580: 2579: 2576: 2574: 2571: 2569: 2566: 2564: 2561: 2559: 2556: 2554: 2551: 2549: 2546: 2544: 2541: 2539: 2536: 2534: 2531: 2529: 2526: 2525: 2523: 2519: 2513: 2510: 2506: 2503: 2501: 2498: 2496: 2493: 2491: 2488: 2486: 2483: 2481: 2478: 2477: 2476: 2473: 2471: 2468: 2466: 2463: 2461: 2458: 2456: 2453: 2451: 2448: 2446: 2443: 2439: 2436: 2434: 2431: 2429: 2426: 2424: 2421: 2420: 2419: 2416: 2414: 2411: 2409: 2406: 2404: 2401: 2399: 2396: 2394: 2391: 2389: 2386: 2384: 2381: 2379: 2376: 2374: 2371: 2367: 2364: 2362: 2359: 2358: 2357: 2354: 2352: 2349: 2347: 2344: 2342: 2339: 2337: 2334: 2332: 2329: 2327: 2324: 2322: 2319: 2317: 2314: 2312: 2309: 2307: 2304: 2302: 2299: 2297: 2294: 2292: 2289: 2287: 2284: 2280: 2277: 2275: 2272: 2271: 2270: 2267: 2265: 2262: 2260: 2257: 2255: 2252: 2248: 2245: 2243: 2240: 2238: 2235: 2233: 2230: 2229: 2228: 2225: 2223: 2220: 2218: 2215: 2211: 2208: 2207: 2206: 2203: 2201: 2198: 2196: 2193: 2191: 2188: 2186: 2183: 2179: 2176: 2174: 2171: 2169: 2166: 2165: 2164: 2161: 2159: 2156: 2152: 2149: 2147: 2144: 2142: 2139: 2137: 2134: 2132: 2129: 2128: 2127: 2124: 2123: 2121: 2117: 2112: 2108: 2104: 2097: 2092: 2090: 2085: 2083: 2078: 2077: 2074: 2060: 2054: 2049: 2045: 2039: 2034: 2030: 2024: 2019: 2015: 2006: 2001: 1999: 1994: 1992: 1987: 1986: 1983: 1976: 1972: 1971: 1966: 1962: 1958: 1955: 1951: 1948: 1947: 1943: 1936: 1932: 1927: 1922: 1918: 1914: 1910: 1906: 1902: 1897: 1893: 1889: 1884: 1879: 1876:(2): 129–40. 1875: 1871: 1867: 1862: 1861: 1856: 1847: 1843: 1838: 1833: 1828: 1823: 1819: 1815: 1811: 1804: 1801: 1796: 1792: 1788: 1784: 1781:(3): 128–32. 1780: 1776: 1769: 1766: 1761: 1757: 1752: 1747: 1742: 1737: 1733: 1729: 1726:(3): e59354. 1725: 1721: 1720: 1715: 1708: 1705: 1700: 1696: 1691: 1686: 1682: 1678: 1674: 1667: 1664: 1659: 1655: 1650: 1645: 1641: 1637: 1633: 1629: 1625: 1618: 1616: 1612: 1607: 1601: 1598: 1593: 1589: 1585: 1581: 1574: 1571: 1566: 1562: 1556: 1553: 1548: 1544: 1538: 1535: 1531: 1527: 1522: 1520: 1518: 1514: 1510: 1506: 1501: 1499: 1497: 1493: 1486: 1484: 1482: 1477: 1469: 1467: 1465: 1460: 1457: 1455: 1451: 1447: 1443: 1439: 1435: 1431: 1426: 1424: 1420: 1416: 1415:Interleukin-4 1412: 1411:messenger RNA 1408: 1407:interleukin-1 1404: 1400: 1395: 1393: 1389: 1385: 1381: 1377: 1373: 1369: 1365: 1357: 1355: 1353: 1349: 1345: 1342: 1338: 1334: 1330: 1326: 1325:blood vessels 1322: 1318: 1314: 1310: 1302: 1300: 1298: 1294: 1291: 1287: 1283: 1279: 1275: 1271: 1267: 1255: 1250: 1246: 1242: 1239: 1235: 1228: 1226: 1223: 1219: 1215: 1211: 1208: 1204: 1200: 1193: 1191: 1185: 1181: 1178: 1172: 1170: 1166: 1162: 1156: 1152: 1149: 1145: 1138: 1136: 1130: 1126: 1123: 1117: 1115: 1111: 1107: 1101: 1097: 1094: 1092:RefSeq (mRNA) 1090: 1083: 1082: 1077: 1073: 1070: 1064: 1063: 1058: 1054: 1051: 1049: 1045: 1038: 1037: 1032: 1028: 1025: 1019: 1018: 1013: 1009: 1006: 1004: 1000: 993: 992: 987: 983: 980: 974: 973: 968: 964: 961: 959: 955: 952: 949: 947: 944: 940: 937: 933: 929: 922: 918: 913: 907: 904: 902: 899: 897: 894: 892: 889: 887: 884: 882: 879: 877: 874: 872: 869: 867: 864: 862: 859: 857: 856:viral process 854: 852: 849: 847: 844: 842: 839: 837: 834: 832: 829: 827: 824: 822: 819: 817: 814: 812: 809: 807: 806:cell adhesion 804: 802: 799: 797: 794: 792: 789: 787: 784: 782: 779: 777: 774: 772: 769: 767: 764: 762: 759: 757: 754: 752: 749: 747: 744: 742: 739: 738: 736: 733: 732: 726: 723: 721: 718: 716: 713: 711: 708: 706: 703: 701: 698: 696: 693: 691: 688: 686: 683: 681: 678: 676: 673: 671: 668: 666: 663: 661: 658: 656: 653: 651: 648: 646: 643: 642: 640: 637: 636: 630: 627: 625: 622: 620: 617: 616: 614: 611: 610: 607: 606:Gene ontology 603: 599: 587: 582: 578: 573: 570: 568: 564: 556: 551: 540: 536: 532: 528: 524: 520: 516: 512: 508: 504: 503: 500: 496: 491: 488: 479:kidney tubule 478: 474: 470: 466: 462: 458: 454: 450: 446: 442: 441: 438: 434: 429: 426: 425: 422: 420: 416: 414: 413: 409: 408: 405: 403: 399: 395: 391: 387: 379: 374: 370: 366: 361: 351: 347: 340: 333: 327: 320: 312: 308: 304: 299: 295: 290: 286: 278: 273: 269: 265: 260: 250: 246: 239: 232: 226: 219: 215: 209: 205: 201: 196: 192: 187: 183: 179: 175: 171: 167: 163: 159: 155: 151: 147: 143: 135: 130: 123: 118: 113: 102: 100: 96: 92: 86: 81: 78: 77: 73: 70: 63: 59: 54: 50: 46: 41: 36: 33: 29: 22: 4610: 4192: 3624: 3544: 3522: 3500: 3347: 3310: 3273: 3226: 3196: 3169: 2991: 2897: 2892: 2745: 2474: 2226: 2058: 2043: 2028: 1968: 1908: 1904: 1873: 1869: 1817: 1813: 1803: 1778: 1774: 1768: 1723: 1717: 1707: 1680: 1676: 1666: 1631: 1628:J. Cell Biol 1627: 1600: 1583: 1579: 1573: 1564: 1555: 1546: 1537: 1473: 1470:Pharmacology 1461: 1458: 1427: 1418: 1405:(TNF-α) and 1396: 1378:to vascular 1361: 1306: 1289: 1281: 1277: 1273: 1269: 1265: 1264: 1187: 1165:NP_001186763 1158: 1132: 1114:NM_001199834 1103: 1079: 1060: 1034: 1015: 989: 970: 950: 945: 781:human ageing 685:cell surface 417: 410: 376:115,923,337 363:115,903,598 275:100,739,045 262:100,719,742 137:External IDs 88: 32: 4433:Desmocollin 2011:PDB gallery 1380:endothelium 1372:eosinophils 1364:lymphocytes 1344:transcripts 1329:endothelial 891:innervation 680:microvillus 537:human fetus 115:Identifiers 28:Cadmium-106 4664:Categories 4606:L-selectin 4577:P-selectin 4572:L-selectin 4567:E-selectin 4490:T-cadherin 4411:Desmoglein 4403:Desmosomal 2109:(see also 1905:Cancer Res 1532:, May 2017 1511:, May 2017 1487:References 1313:antibodies 705:sarcolemma 665:filopodium 467:glomerulus 421:(ortholog) 158:HomoloGene 4559:Selectins 4376:Classical 4368:Cadherins 4272:Integrins 4203:L1 family 1438:integrins 1376:basophils 1368:monocytes 1333:cytokines 1303:Structure 1190:NP_035823 1169:NP_542413 1161:NP_001069 1135:NM_011693 1110:NM_001078 1106:NM_080682 936:Orthologs 459:vena cava 166:GeneCards 4612:integrin 4161:IgSF CAM 2103:Proteins 2061:: VCAM-1 1935:17616653 1892:15548573 1846:32005712 1795:16475855 1760:23555021 1719:PLOS One 1699:27501520 1658:12082081 1528:– 1507:– 1483:target. 1476:melanoma 1474:Certain 1446:interact 1358:Function 1335:. It is 1238:Wikidata 915:Sources: 700:podosome 660:membrane 3911:301–350 3705:251–300 3657:CD240CE 3454:201–250 3138:151–200 2861:101–150 1975:PDBe-KB 1965:UniProt 1926:3179385 1837:7035611 1751:3595282 1728:Bibcode 1649:2173557 1530:Ensembl 1509:Ensembl 1466:(MSC). 1286:protein 1284:) is a 1048:UniProt 1003:Ensembl 942:Species 921:QuickGO 396:pattern 122:Aliases 4675:SIGLEC 4474:PCDH19 4469:PCDH15 4340:ITGA2B 4230:Nectin 4208:L1-CAM 4198:PE-CAM 4193:VCAM-1 3918:CD300A 3877:CDw293 3662:CD240D 3523:CD213a 3501:CDw210 3466:CD202b 3440:CDw199 3435:CDw198 3089:CD140b 2521:51–100 1970:P19320 1956:(MeSH) 1950:VCAM-1 1933:  1923:  1890:  1844:  1834:  1793:  1758:  1748:  1697:  1656:  1646:  1454:Moesin 1430:ligand 1374:, and 1274:VCAM-1 1224:search 1222:PubMed 1081:P29533 1062:P19320 958:Entrez 567:BioGPS 541:thymus 533:atrium 513:dermis 509:spleen 463:spleen 254:1p21.2 146:192225 4649:EpCAM 4644:CD146 4621:LFA-1 4617:VLA-4 4590:Other 4545:CDH10 4535:CDH17 4530:CDH16 4525:CDH15 4520:CDH12 4515:CDH11 4464:PCDH1 4344:ITGB3 4326:CD49d 4322:VLA-4 4312:CD11b 4298:CD11c 4284:CD11a 4280:LFA-1 4260:CD155 4255:CADM3 4250:CADM1 4245:PVRL3 4240:PVRL2 4235:PVRL1 4218:NFASC 4213:NRCAM 4169:N-CAM 4098:CD350 4093:CD349 4088:CD344 4083:CD340 4078:CD339 4073:CD338 4068:CD337 4063:CD336 4058:CD335 4053:CD334 4048:CD333 4043:CD332 4038:CD331 4033:CD329 4028:CD328 4023:CD327 4018:CD326 4013:CD325 4008:CD324 4003:CD322 3998:CD321 3993:CD320 3988:CD318 3983:CD317 3978:CD316 3973:CD315 3968:CD314 3963:CD312 3958:CD309 3953:CD307 3948:CD306 3943:CD305 3938:CD304 3933:CD303 3928:CD302 3923:CD301 3902:CD299 3897:CD298 3892:CD297 3887:CD295 3882:CD294 3872:CD292 3867:CD290 3862:CD289 3857:CD288 3852:CD286 3847:CD284 3842:CD283 3837:CD282 3832:CD281 3827:CD280 3822:CD279 3817:CD278 3812:CD276 3807:CD275 3802:CD274 3797:CD273 3792:CD272 3787:CD271 3782:CD269 3777:CD268 3772:CD267 3767:CD266 3762:CD265 3757:CD264 3752:CD263 3747:CD262 3742:CD261 3737:CD258 3732:CD257 3727:CD256 3722:CD254 3717:CD253 3712:CD252 3696:CD249 3691:CD248 3687:CD247 3682:CD246 3677:CD244 3672:CD243 3667:CD241 3652:CD239 3647:CD238 3642:CD236 3625:CD235 3620:CD234 3615:CD233 3610:CD230 3605:CD229 3600:CD228 3595:CD227 3590:CD226 3585:CD225 3580:CD224 3575:CD223 3570:CD222 3565:CD221 3560:CD220 3545:CD218 3540:CD217 3518:CD212 3496:CD209 3491:CD208 3486:CD207 3481:CD206 3476:CD205 3471:CD204 3461:CD201 3445:CD200 3430:CD197 3425:CD196 3420:CD195 3415:CD194 3410:CD193 3405:CD192 3400:CD191 3395:CD186 3390:CD185 3385:CD184 3380:CD183 3375:CD182 3370:CD181 3365:CD180 3348:CD179 3343:CD178 3338:CD177 3333:CD174 3311:CD172 3306:CD171 3301:CD170 3296:CD169 3291:CD168 3274:CD167 3269:CD166 3264:CD164 3259:CD163 3254:CD162 3249:CD161 3244:CD160 3227:CD159 3197:CD158 3192:CD157 3170:CD156 3165:CD155 3160:CD154 3155:CD153 3150:CD152 3145:CD151 3129:CD150 3124:CD148 3119:CD147 3114:CD146 3109:CD144 3104:CD143 3099:CD142 3094:CD141 3084:CD138 3079:CD137 3074:CD136 3069:CD135 3064:CD134 3059:CD133 3054:CD132 3049:CD131 3044:CD130 3039:CD129 3034:CD127 3029:CD126 3024:CD125 3019:CD124 3014:CD123 3009:CD122 2992:CD121 2975:CD120 2970:CD119 2965:CD118 2960:CD117 2955:CD116 2950:CD115 2945:CD114 2940:CD113 2935:CD112 2930:CD111 2925:CD110 2920:CD109 2915:CD108 2898:CD107 2893:CD106 2888:CD105 2883:CD104 2878:CD103 2873:CD102 2868:CD101 2852:CD100 1448:with 1434:VLA-4 1423:NF-κB 1419:VCAM1 1290:VCAM1 1282:CD106 1276:) or 991:22329 951:Mouse 946:Human 917:Amigo 419:Mouse 412:Human 359:Start 294:Mouse 258:Start 191:Human 170:VCAM1 154:98926 129:VCAM1 38:VCAM1 4639:CD44 4634:CD24 4601:CD44 4540:CDH9 4510:CDH8 4505:CDH6 4500:CDH5 4495:CDH4 4445:DSC3 4441:DSC2 4437:DSC1 4427:DSG4 4423:DSG3 4419:DSG2 4415:DSG1 4393:CDH3 4388:CDH2 4383:CDH1 4330:CD29 4316:CD18 4302:CD18 4288:CD18 4223:CHL1 4179:ICAM 2847:CD99 2842:CD98 2837:CD97 2832:CD96 2827:CD95 2822:CD94 2817:CD93 2812:CD92 2808:CD91 2803:CD90 2798:CD89 2793:CD88 2788:CD87 2783:CD86 2746:CD85 2741:CD84 2736:CD83 2731:CD82 2726:CD81 2721:CD80 2704:CD79 2699:CD78 2694:CD74 2689:CD73 2684:CD72 2679:CD71 2674:CD70 2669:CD69 2664:CD68 2627:CD66 2605:CD64 2600:CD63 2578:CD62 2573:CD61 2568:CD59 2563:CD58 2558:CD57 2553:CD56 2548:CD55 2543:CD54 2538:CD53 2533:CD52 2528:CD51 2512:CD50 2475:CD49 2470:CD48 2465:CD47 2460:CD46 2455:CD45 2450:CD44 2445:CD43 2418:CD42 2413:CD41 2408:CD40 2403:CD39 2398:CD38 2393:CD37 2388:CD36 2383:CD35 2378:CD34 2373:CD33 2356:CD32 2351:CD31 2346:CD30 2341:CD29 2336:CD28 2331:CD27 2326:CD26 2321:CD25 2316:CD24 2311:CD23 2306:CD22 2301:CD21 2296:CD20 2291:CD19 2286:CD18 2269:CD16 2264:CD15 2259:CD14 2254:CD13 2227:CD11 2222:CD10 2119:1–50 2059:1vsc 2044:1vca 2029:1ij9 1963:for 1931:PMID 1888:PMID 1842:PMID 1791:PMID 1756:PMID 1695:PMID 1654:PMID 1481:drug 1452:and 1432:for 1390:and 1315:and 1293:gene 972:7412 402:Bgee 350:Band 311:Chr. 249:Band 208:Chr. 142:OMIM 99:1VSC 95:1VCA 91:1IJ9 72:RCSB 69:PDBe 21:WNCD 2217:CD9 2205:CD8 2200:CD7 2195:CD6 2190:CD5 2185:CD4 2163:CD3 2158:CD2 2131:a-c 2126:CD1 1961:PDB 1921:PMC 1913:doi 1878:doi 1832:PMC 1822:doi 1818:117 1783:doi 1779:151 1746:PMC 1736:doi 1685:doi 1644:PMC 1636:doi 1632:157 1588:doi 1450:EZR 1341:RNA 372:End 271:End 174:OMA 162:838 150:MGI 62:PDB 4666:: 4619:, 4599:: 4443:, 4439:, 4425:, 4421:, 4417:, 4185:, 4142:: 3689:- 2810:- 2151:1E 2146:1D 2141:1B 2136:1A 2105:: 1967:: 1929:. 1919:. 1909:67 1907:. 1903:. 1886:. 1874:77 1872:. 1868:. 1840:. 1830:. 1816:. 1812:. 1789:. 1777:. 1754:. 1744:. 1734:. 1722:. 1716:. 1693:. 1681:14 1679:. 1675:. 1652:. 1642:. 1630:. 1626:. 1614:^ 1584:58 1582:. 1563:. 1545:. 1516:^ 1495:^ 1456:. 1394:. 1370:, 1366:, 1354:. 1299:. 919:/ 378:bp 365:bp 277:bp 264:bp 172:; 168:: 164:; 160:: 156:; 152:: 148:; 144:: 97:, 93:, 4623:) 4615:( 4447:) 4435:( 4429:) 4413:( 4346:) 4342:+ 4338:( 4332:) 4328:+ 4324:( 4318:) 4314:+ 4310:( 4304:) 4300:+ 4296:( 4290:) 4286:+ 4282:( 4189:) 4187:5 4183:1 4181:( 4175:) 4171:( 4132:e 4125:t 4118:v 3635:b 3630:a 3556:) 3554:b 3549:a 3547:( 3533:2 3528:1 3511:b 3506:a 3358:b 3353:a 3326:g 3321:b 3316:a 3284:b 3279:a 3237:c 3232:a 3223:) 3221:k 3216:i 3211:e 3206:d 3201:a 3199:( 3185:c 3180:b 3175:a 3002:b 2997:a 2985:b 2980:a 2908:b 2903:a 2776:k 2771:j 2766:h 2761:e 2756:d 2751:a 2714:b 2709:a 2657:f 2652:e 2647:d 2642:c 2637:b 2632:a 2620:C 2615:B 2610:A 2593:P 2588:L 2583:E 2505:f 2500:e 2495:d 2490:c 2485:b 2480:a 2438:d 2433:c 2428:b 2423:a 2366:B 2361:A 2279:B 2274:A 2247:d 2242:c 2237:b 2232:a 2210:a 2178:ε 2173:δ 2168:γ 2113:) 2095:e 2088:t 2081:v 2004:e 1997:t 1990:v 1977:. 1937:. 1915:: 1894:. 1880:: 1848:. 1824:: 1797:. 1785:: 1762:. 1738:: 1730:: 1724:8 1701:. 1687:: 1660:. 1638:: 1608:. 1594:. 1590:: 1567:. 1549:. 1280:( 1272:( 296:) 193:) 176:: 30:. 23:.

Index

WNCD
Cadmium-106

PDB
PDBe
RCSB
1IJ9
1VCA
1VSC
Aliases
VCAM1
OMIM
192225
MGI
98926
HomoloGene
838
GeneCards
VCAM1
OMA
VCAM1 - orthologs
Human
Chromosome 1 (human)
Chr.
Chromosome 1 (human)
Chromosome 1 (human)
Genomic location for VCAM1
Genomic location for VCAM1
Band
bp

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