242:
219:
116:
141:
493:
248:
147:
1652:
1031:
to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including
1287:
Rajasekariah P, Eyre HJ, Stanley KK, et al. (1999). "Molecular cloning and characterization of a cDNA encoding the human leucocyte vacuolar protein sorting (h1Vps45)".
255:
154:
1258:
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library".
711:
692:
77:
1492:
Kim BY, Ueda M, Kominami E, et al. (2004). "Identification of mouse Vps16 and biochemical characterization of mammalian class C Vps complex".
1601:"Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes"
1359:
de Renzis S, Sönnichsen B, Zerial M (2002). "Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes".
1721:
1697:
1113:
1095:
1716:
1194:
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides".
931:
241:
938:
218:
1175:
1082:
1061:
1012:
1078:
140:
115:
1057:
57:
1318:"Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain"
254:
153:
247:
146:
1690:
1133:"Mammalian homologues of yeast vacuolar protein sorting (vps) genes implicated in Golgi-to-lysosome trafficking"
1024:
756:
65:
1558:"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)"
737:
1683:
1452:
129:
44:
889:
885:
834:
830:
826:
1384:
89:
1441:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"
914:
893:
859:
838:
1630:
1587:
1544:
1509:
1480:
1427:
1376:
1347:
1304:
1275:
1246:
1211:
1154:
1028:
1016:
37:
1667:
1620:
1612:
1577:
1569:
1534:
1501:
1470:
1460:
1417:
1409:
1368:
1337:
1329:
1296:
1267:
1236:
1203:
1144:
334:
265:
209:
164:
492:
85:
309:
1456:
48:, H1, H1SCN5, VPS45A, VPS45B, VPS54A, VSP45, VSP45A, vacuolar protein sorting 45 homolog
1625:
1600:
1342:
1317:
1582:
1557:
1475:
1440:
1422:
1397:
1300:
1271:
1149:
1132:
626:
621:
616:
611:
606:
590:
585:
580:
575:
570:
565:
560:
555:
539:
534:
1710:
1207:
521:
1663:
1388:
1033:
327:
106:
69:
93:
1118:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1100:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1019:
plays an important role in segregation of intracellular molecules into distinct
1505:
410:
226:
123:
73:
1523:"Complete sequencing and characterization of 21,243 full-length human cDNAs"
1241:
1224:
1020:
656:
470:
348:
293:
280:
192:
179:
81:
1634:
1591:
1548:
1513:
1484:
1465:
1431:
1413:
1380:
1351:
1308:
1333:
1279:
1250:
1215:
1158:
978:
973:
962:
801:
782:
1176:"Entrez Gene: VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)"
1616:
1573:
1316:
Nielsen E, Christoforidis S, Uttenweiler-Joseph S, et al. (2000).
994:
768:
723:
946:
678:
1651:
1539:
1522:
1372:
641:
637:
1659:
1225:"Identification of a mammalian Golgi Sec1p-like protein, mVps45"
1001:
501:
61:
1439:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
1023:. Genetic studies in yeast have identified more than 40
317:
1671:
1556:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
1599:
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006).
482:
1396:
Dulubova I, Yamaguchi T, Gao Y, et al. (2002).
1131:
Pevsner J, Hsu SC, Hyde PS, Scheller RH (Feb 1997).
907:
878:
852:
819:
433:
dentate gyrus of hippocampal formation granule cell
1521:Ota T, Suzuki Y, Nishikawa T, et al. (2004).
1223:Tellam JT, James DE, Stevens TH, Piper RC (1997).
1074:
1072:
1070:
1053:
1051:
1049:
264:
163:
16:Protein-coding gene in the species Homo sapiens
1079:GRCm38: Ensembl release 89: ENSMUSG00000015747
991:Vacuolar protein sorting-associated protein 45
1691:
8:
1058:GRCh38: Ensembl release 89: ENSG00000136631
1698:
1684:
652:
517:
305:
204:
101:
1624:
1581:
1538:
1474:
1464:
1421:
1341:
1240:
1148:
1170:
1168:
1045:
1398:"How Tlg2p/syntaxin 16 'snares' Vps45"
627:vesicle docking involved in exocytosis
18:
269:
230:
225:
168:
127:
122:
7:
1648:
1646:
1670:. You can help Knowledge (XXG) by
904:
875:
849:
816:
792:
773:
747:
728:
702:
683:
487:
405:
343:
322:
14:
997:that in humans is encoded by the
1650:
491:
253:
246:
240:
217:
152:
145:
139:
114:
612:intracellular protein transport
556:integral component of membrane
502:More reference expression data
471:More reference expression data
449:Region I of hippocampus proper
367:right hemisphere of cerebellum
1:
1722:Human chromosome 1 gene stubs
1494:Biochem. Biophys. Res. Commun
1301:10.1016/S1357-2725(99)00017-5
1272:10.1016/S0378-1119(97)00411-3
1150:10.1016/S0378-1119(96)00367-8
238:
137:
1445:Proc. Natl. Acad. Sci. U.S.A
1208:10.1016/0378-1119(94)90802-8
1717:Genes on human chromosome 1
1738:
1645:
1506:10.1016/j.bbrc.2003.10.030
1289:Int. J. Biochem. Cell Biol
622:vesicle-mediated transport
1114:"Mouse PubMed Reference:"
1096:"Human PubMed Reference:"
977:
972:
968:
961:
945:
932:Chr 1: 150.07 – 150.15 Mb
926:
911:
882:
871:
856:
823:
812:
799:
795:
780:
776:
767:
754:
750:
735:
731:
722:
709:
705:
690:
686:
677:
662:
655:
651:
635:
520:
516:
499:
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481:
468:
417:
408:
355:
346:
316:
308:
304:
287:
274:
237:
216:
207:
203:
186:
173:
136:
113:
104:
100:
55:
52:
42:
35:
30:
26:
21:
1027:(VPS) genes involved in
1025:vacuolar protein sorting
1242:10.1074/jbc.272.10.6187
939:Chr 3: 95.91 – 95.97 Mb
1466:10.1073/pnas.242603899
1034:inflammatory mediators
421:neural layer of retina
271:3 F2.1|3 41.65 cM
1334:10.1083/jcb.151.3.601
363:cerebellar hemisphere
1414:10.1093/emboj/cdf381
429:facial motor nucleus
371:right adrenal cortex
232:Chromosome 3 (mouse)
130:Chromosome 1 (human)
1457:2002PNAS...9916899M
445:ganglionic eminence
391:left adrenal cortex
375:ganglionic eminence
1658:This article on a
1617:10.1101/gr.4039406
1574:10.1101/gr.2596504
757:ENSMUSG00000015747
600:Biological process
586:cellular component
549:Cellular component
540:molecular function
528:Molecular function
457:supraoptic nucleus
383:left adrenal gland
1679:
1678:
1451:(26): 16899–903.
1029:vesicle transport
988:
987:
984:
983:
957:
956:
922:
921:
901:
900:
867:
866:
846:
845:
808:
807:
789:
788:
763:
762:
744:
743:
718:
717:
699:
698:
647:
646:
617:blood coagulation
607:protein transport
571:endosome membrane
512:
511:
508:
507:
477:
476:
464:
463:
402:
401:
379:cerebellar vermis
359:cerebellar cortex
300:
299:
199:
198:
94:VPS45 - orthologs
1729:
1700:
1693:
1686:
1654:
1647:
1638:
1628:
1595:
1585:
1552:
1542:
1517:
1488:
1478:
1468:
1435:
1425:
1392:
1355:
1345:
1312:
1283:
1254:
1244:
1219:
1180:
1179:
1172:
1163:
1162:
1152:
1128:
1122:
1121:
1110:
1104:
1103:
1092:
1086:
1076:
1065:
1055:
970:
969:
941:
934:
917:
905:
896:
876:
872:RefSeq (protein)
862:
850:
841:
817:
793:
774:
748:
729:
703:
684:
653:
591:synaptic vesicle
518:
504:
495:
488:
473:
413:
411:Top expressed in
406:
351:
349:Top expressed in
344:
323:
306:
296:
283:
272:
257:
250:
244:
233:
221:
205:
195:
182:
171:
156:
149:
143:
132:
118:
102:
96:
47:
40:
19:
1737:
1736:
1732:
1731:
1730:
1728:
1727:
1726:
1707:
1706:
1705:
1704:
1643:
1641:
1598:
1568:(10B): 2121–7.
1555:
1520:
1491:
1438:
1408:(14): 3620–31.
1395:
1358:
1315:
1286:
1266:(1–2): 149–56.
1257:
1235:(10): 6187–93.
1222:
1193:
1189:
1187:Further reading
1184:
1183:
1174:
1173:
1166:
1130:
1129:
1125:
1112:
1111:
1107:
1094:
1093:
1089:
1077:
1068:
1056:
1047:
1042:
1017:protein sorting
1010:
979:View/Edit Mouse
974:View/Edit Human
937:
930:
927:Location (UCSC)
913:
892:
888:
884:
858:
837:
833:
829:
825:
738:ENSG00000136631
631:
595:
566:Golgi apparatus
544:
535:protein binding
500:
469:
460:
455:
451:
447:
443:
441:muscle of thigh
439:
435:
431:
427:
423:
409:
398:
395:Achilles tendon
393:
389:
385:
381:
377:
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291:
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258:
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231:
208:Gene location (
190:
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150:
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105:Gene location (
56:
43:
36:
17:
12:
11:
5:
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1702:
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1655:
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1596:
1553:
1540:10.1038/ng1285
1518:
1489:
1436:
1393:
1373:10.1038/ncb744
1361:Nat. Cell Biol
1356:
1313:
1284:
1255:
1220:
1202:(1–2): 171–4.
1190:
1188:
1185:
1182:
1181:
1164:
1123:
1105:
1087:
1066:
1044:
1043:
1041:
1038:
1009:
1006:
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985:
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981:
976:
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958:
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943:
942:
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844:
843:
821:
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786:
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771:
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751:
745:
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741:
733:
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719:
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715:
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688:
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675:
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649:
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644:
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630:
629:
624:
619:
614:
609:
603:
601:
597:
596:
594:
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588:
583:
581:Golgi membrane
578:
573:
568:
563:
558:
552:
550:
546:
545:
543:
542:
537:
531:
529:
525:
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514:
513:
510:
509:
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505:
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372:
368:
364:
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353:
352:
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331:
320:
314:
313:
310:RNA expression
302:
301:
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289:
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284:
276:
273:
268:
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261:
252:
245:
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235:
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214:
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188:
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175:
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167:
161:
160:
151:
144:
138:
134:
133:
126:
120:
119:
111:
110:
98:
97:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1734:
1723:
1720:
1718:
1715:
1714:
1712:
1701:
1696:
1694:
1689:
1687:
1682:
1681:
1675:
1673:
1669:
1665:
1661:
1656:
1653:
1649:
1644:
1636:
1632:
1627:
1622:
1618:
1614:
1610:
1606:
1602:
1597:
1593:
1589:
1584:
1579:
1575:
1571:
1567:
1563:
1559:
1554:
1550:
1546:
1541:
1536:
1532:
1528:
1524:
1519:
1515:
1511:
1507:
1503:
1500:(3): 577–82.
1499:
1495:
1490:
1486:
1482:
1477:
1472:
1467:
1462:
1458:
1454:
1450:
1446:
1442:
1437:
1433:
1429:
1424:
1419:
1415:
1411:
1407:
1403:
1399:
1394:
1390:
1386:
1382:
1378:
1374:
1370:
1367:(2): 124–33.
1366:
1362:
1357:
1353:
1349:
1344:
1339:
1335:
1331:
1328:(3): 601–12.
1327:
1323:
1319:
1314:
1310:
1306:
1302:
1298:
1295:(6): 683–94.
1294:
1290:
1285:
1281:
1277:
1273:
1269:
1265:
1261:
1256:
1252:
1248:
1243:
1238:
1234:
1230:
1229:J. Biol. Chem
1226:
1221:
1217:
1213:
1209:
1205:
1201:
1197:
1192:
1191:
1186:
1177:
1171:
1169:
1165:
1160:
1156:
1151:
1146:
1143:(1–2): 7–14.
1142:
1138:
1134:
1127:
1124:
1119:
1115:
1109:
1106:
1101:
1097:
1091:
1088:
1084:
1080:
1075:
1073:
1071:
1067:
1063:
1059:
1054:
1052:
1050:
1046:
1039:
1037:
1035:
1030:
1026:
1022:
1018:
1014:
1007:
1005:
1003:
1000:
996:
992:
980:
975:
971:
967:
964:
960:
953:
951:
948:
944:
940:
936:
933:
929:
925:
918:
916:
910:
906:
903:
897:
895:
891:
887:
881:
877:
874:
870:
863:
861:
855:
851:
848:
842:
840:
836:
832:
828:
822:
818:
815:
813:RefSeq (mRNA)
811:
804:
803:
798:
794:
791:
785:
784:
779:
775:
772:
770:
766:
759:
758:
753:
749:
746:
740:
739:
734:
730:
727:
725:
721:
714:
713:
708:
704:
701:
695:
694:
689:
685:
682:
680:
676:
673:
670:
668:
665:
661:
658:
654:
650:
643:
639:
634:
628:
625:
623:
620:
618:
615:
613:
610:
608:
605:
604:
602:
599:
598:
592:
589:
587:
584:
582:
579:
577:
574:
572:
569:
567:
564:
562:
559:
557:
554:
553:
551:
548:
547:
541:
538:
536:
533:
532:
530:
527:
526:
523:
522:Gene ontology
519:
515:
503:
498:
494:
489:
486:
484:
480:
472:
467:
456:
452:
448:
444:
440:
436:
432:
428:
424:
420:
419:
416:
412:
407:
404:
394:
390:
386:
382:
378:
374:
370:
366:
362:
358:
357:
354:
350:
345:
342:
341:
338:
336:
332:
330:
329:
325:
324:
321:
319:
315:
311:
307:
303:
295:
290:
286:
282:
277:
267:
263:
256:
249:
243:
236:
228:
224:
220:
215:
211:
206:
202:
194:
189:
185:
181:
176:
166:
162:
155:
148:
142:
135:
131:
125:
121:
117:
112:
108:
103:
99:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
1672:expanding it
1664:chromosome 1
1657:
1642:
1611:(1): 55–65.
1608:
1604:
1565:
1561:
1530:
1526:
1497:
1493:
1448:
1444:
1405:
1401:
1364:
1360:
1325:
1322:J. Cell Biol
1321:
1292:
1288:
1263:
1259:
1232:
1228:
1199:
1195:
1140:
1136:
1126:
1117:
1108:
1099:
1090:
1011:
998:
990:
989:
912:
890:NP_001266283
886:NP_001266282
883:
857:
835:NM_001279355
831:NM_001279354
827:NM_001279353
824:
800:
781:
755:
736:
710:
691:
671:
666:
437:right kidney
333:
326:
191:150,145,329
178:150,067,279
53:External IDs
1533:(1): 40–5.
425:neural tube
292:95,965,778
279:95,907,144
31:Identifiers
1711:Categories
1605:Genome Res
1562:Genome Res
1527:Nat. Genet
1085:, May 2017
1064:, May 2017
1040:References
1021:organelles
337:(ortholog)
74:HomoloGene
1662:on human
1015:mediated
915:NP_038869
894:NP_009190
860:NM_013841
839:NM_007259
657:Orthologs
82:GeneCards
1635:16344560
1592:15489334
1549:14702039
1514:14623309
1485:12477932
1432:12110575
1381:11788822
1352:11062261
1309:10404641
1081:–
1060:–
1008:Function
963:Wikidata
636:Sources:
576:membrane
561:endosome
387:monocyte
1626:1356129
1453:Bibcode
1389:6596498
1343:2185588
1280:9373149
1251:9045632
1216:8125298
1159:8996080
1083:Ensembl
1062:Ensembl
1013:Vesicle
995:protein
769:UniProt
724:Ensembl
663:Species
642:QuickGO
312:pattern
38:Aliases
1633:
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1590:
1583:528928
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1476:139241
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1423:126126
1420:
1402:EMBO J
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1249:
1214:
1157:
949:search
947:PubMed
802:P97390
783:Q9NRW7
679:Entrez
483:BioGPS
170:1q21.2
70:891965
62:610035
1666:is a
1385:S2CID
999:VPS45
993:is a
712:22365
693:11311
672:Mouse
667:Human
638:Amigo
335:Mouse
328:Human
275:Start
210:Mouse
174:Start
107:Human
86:VPS45
45:VPS45
22:VPS45
1668:stub
1660:gene
1631:PMID
1588:PMID
1545:PMID
1510:PMID
1481:PMID
1428:PMID
1377:PMID
1348:PMID
1305:PMID
1276:PMID
1260:Gene
1247:PMID
1212:PMID
1196:Gene
1155:PMID
1137:Gene
1002:gene
453:lens
318:Bgee
266:Band
227:Chr.
165:Band
124:Chr.
78:5250
58:OMIM
1621:PMC
1613:doi
1578:PMC
1570:doi
1535:doi
1502:doi
1498:311
1471:PMC
1461:doi
1418:PMC
1410:doi
1369:doi
1338:PMC
1330:doi
1326:151
1297:doi
1268:doi
1264:200
1237:doi
1233:272
1204:doi
1200:138
1145:doi
1141:183
288:End
187:End
90:OMA
66:MGI
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