Knowledge (XXG)

VPS4A

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Scheuring S, Bodor O, Röhricht RA, Müller S, Beyer A, Köhrer K (1999). "Cloning, characterisation, and functional expression of the Mus musculus SKD1 gene in yeast demonstrates that the mouse SKD1 and the yeast VPS4 genes are orthologues and involved in intracellular protein trafficking".
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Hu RM, Han ZG, Song HD, Peng YD, Huang QH, Ren SX, Gu YJ, Huang CH, Li YB, Jiang CL, Fu G, Zhang QH, Gu BW, Dai M, Mao YF, Gao GF, Rong R, Ye M, Zhou J, Xu SH, Gu J, Shi JX, Jin WR, Zhang CK, Wu TM, Huang GY, Chen Z, Chen MD, Chen JL (2000).
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Scheuring S, Röhricht RA, Schöning-Burkhardt B, Beyer A, Müller S, Abts HF, Köhrer K (September 2001). "Mammalian cells express two VPS4 proteins both of which are involved in intracellular protein trafficking".
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von Schwedler UK, Stuchell M, Müller B, Ward DM, Chung HY, Morita E, Wang HE, Davis T, He GP, Cimbora DM, Scott A, Kräusslich HG, Kaplan J, Morham SG, Sundquist WI (2003).
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Chen VY, Posada MM, Blazer LL, Zhao T, Rosania GR (2007). "The role of the VPS4A-exosome pathway in the intrinsic egress route of a DNA-binding anticancer drug".
2114:"A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex" 2026:"Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1" 1039: 1020: 145: 1565:
Howard TL, Stauffer DR, Degnin CR, Hollenberg SM (July 2001). "CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins".
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Beyer A, Scheuring S, Müller S, Mincheva A, Lichter P, Köhrer K (2003). "Comparative sequence and expression analyses of four mammalian VPS4 genes".
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Howard TL, Stauffer DR, Degnin CR, Hollenberg SM (2002). "CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins".
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similarity with each other, and also with yeast Vps4 and mouse proteins. Functional studies indicate that both human paralogs associate with the
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family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two
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Chagnon P, Michaud J, Mitchell G, Mercier J, Marion JF, Drouin E, Rasquin-Weber A, Hudson TJ, Richter A (2003).
1084: 133: 1065: 1638:"Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning" 2329: 197: 2186:"Hepatitis B Virus Maturation Is Sensitive to Functional Inhibition of ESCRT-III, Vps4, and γ2-Adaptin" 2235: 2072: 1649: 1465:"ATPase-defective Mammalian VPS4 Localizes to Aberrant Endosomes and Impairs Cholesterol Trafficking" 112: 1341: 1333: 1205: 2172: 1977: 1934: 157: 1720:"Vps4-A (vacuolar protein sorting 4-A) is a binding partner for a novel Rho family GTPase, Rnd2" 1226: 1201: 1175: 1154: 1798:"A Missense Mutation (R565W) in Cirhin (FLJ14728) in North American Indian Childhood Cirrhosis" 2215: 2164: 2135: 2100: 2047: 2012: 1969: 1926: 1891: 1856: 1827: 1784: 1749: 1706: 1677: 1623: 1582: 1530: 1494: 105: 45: 2313: 2205: 2197: 2156: 2125: 2090: 2080: 2037: 2002: 1959: 1916: 1881: 1848: 1817: 1809: 1774: 1739: 1731: 1698: 1667: 1657: 1615: 1574: 1522: 1484: 1476: 402: 333: 277: 232: 840:
ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
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Katoh K, Shibata H, Suzuki H, Nara A, Ishidoh K, Kominami E, Yoshimori T, Maki M (2003).
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ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
2076: 1653: 2210: 2185: 2095: 2060: 1744: 1719: 28: 1964: 1947: 1921: 1905:"AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding" 1904: 1852: 1822: 1797: 1619: 1344:, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to 954: 949: 944: 939: 934: 929: 924: 919: 914: 909: 904: 899: 894: 889: 884: 879: 874: 869: 864: 859: 854: 849: 844: 839: 834: 829: 824: 819: 814: 809: 804: 799: 794: 789: 784: 779: 774: 769: 764: 748: 743: 738: 733: 728: 723: 718: 713: 708: 703: 698: 693: 688: 683: 678: 673: 668: 663: 658: 642: 637: 632: 627: 622: 617: 612: 607: 602: 2356: 2309: 1763:"SKD1 AAA ATPase-dependent endosomal transport is involved in autolysosome formation" 1672: 1637: 1489: 1464: 1349: 1345: 589: 2059:
Scott A, Gaspar J, Stuchell-Brereton MD, Alam SL, Skalicky JJ, Sundquist WI (2005).
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National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
1325: 2061:"Structure and ESCRT-III protein interactions of the MIT domain of human VPS4A" 478: 116:, SKD1, SKD1A, SKD2, VPS4, VPS4-1, vacuolar protein sorting 4 homolog A, CIMDAG 2160: 294: 191: 141: 2085: 1702: 1578: 1337: 984: 538: 416: 361: 348: 260: 247: 149: 2219: 2168: 2139: 2104: 2051: 2042: 2025: 2016: 1973: 1930: 1895: 1886: 1869: 1860: 1831: 1788: 1753: 1710: 1681: 1662: 1627: 1586: 1534: 1526: 1498: 1290: 1285: 2201: 2112:
Tsang HT, Connell JW, Brown SE, Thompson A, Reid E, Sanderson CM (2006).
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Nara A, Mizushima N, Yamamoto A, Kabeya Y, Ohsumi Y, Yoshimori T (2002).
1552:"Entrez Gene: VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)" 1480: 1274: 1129: 1110: 1735: 1332:
of the yeast protein have been identified. They share a high degree of
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Strack B, Calistri A, Craig S, Popova E, Göttlinger HG (2003).
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Lin Y, Kimpler LA, Naismith TV, Lauer JM, Hanson PI (2005).
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positive regulation of viral budding via host ESCRT complex
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Tanaka H, Fujita H, Katoh H, Mori K, Negishi M (2002).
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regulation of protein localization to plasma membrane
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The protein encoded by this gene is a member of the
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dentate gyrus of hippocampal formation granule cell
1406: 1404: 1402: 1385: 1383: 1381: 332: 231: 1340:compartments, and are involved in intracellular 16:Protein-coding gene in the species Homo sapiens 1411:GRCm38: Ensembl release 89: ENSMUSG00000031913 1303:Vacuolar protein sorting-associated protein 4A 2337: 2243: 8: 1390:GRCh38: Ensembl release 89: ENSG00000132612 2344: 2330: 2250: 2236: 2228: 1989:Sachse M, Strous GJ, Klumperman J (2004). 980: 585: 439:Skeletal muscle tissue of rectus abdominis 373: 272: 169: 63: 2209: 2129: 2094: 2084: 2041: 2006: 1963: 1920: 1885: 1821: 1778: 1743: 1671: 1661: 1488: 885:positive regulation of exosomal secretion 1546: 1544: 945:mitotic cytokinesis checkpoint signaling 2265: 1377: 925:actomyosin contractile ring contraction 855:positive regulation of viral life cycle 2184:Lambert C, Döring T, Prange R (2007). 18: 337: 298: 293: 236: 195: 190: 7: 2294: 2292: 1948:"The protein network of HIV budding" 1348:; the gene for the other resides on 905:cytoplasmic microtubule organization 785:viral budding via host ESCRT complex 613:microtubule-severing ATPase activity 2278:: NMR Structure of VPS4A MIT Domain 880:mitotic metaphase plate congression 825:intracellular cholesterol transport 2316:. You can help Knowledge (XXG) by 1463:Bishop N, Woodman P (April 2000). 1216: 1191: 1165: 1144: 1120: 1101: 1075: 1056: 1030: 1011: 950:cytoskeleton-dependent cytokinesis 875:septum digestion after cytokinesis 870:negative regulation of cytokinesis 815:regulation of protein localization 643:protein-containing complex binding 555: 473: 411: 390: 14: 1309:that in humans is encoded by the 2296: 2268: 559: 321: 314: 308: 285: 220: 213: 207: 182: 27: 729:perinuclear region of cytoplasm 608:protein domain specific binding 2368:Human chromosome 16 gene stubs 570:More reference expression data 539:More reference expression data 1: 1965:10.1016/S0092-8674(03)00714-1 1922:10.1016/S0092-8674(03)00653-6 1853:10.1016/S0378-1119(02)01205-2 1620:10.1016/S0378-1119(99)00163-8 935:nuclear envelope organization 930:protein targeting to lysosome 900:ESCRT III complex disassembly 835:vesicle budding from membrane 765:late endosomal microautophagy 306: 205: 2363:Genes on human chromosome 16 2065:Proc. Natl. Acad. Sci. U.S.A 1642:Proc. Natl. Acad. Sci. U.S.A 800:multivesicular body assembly 775:viral release from host cell 2131:10.1016/j.ygeno.2006.04.003 940:nuclear membrane reassembly 2384: 2291: 890:vesicle-mediated transport 618:protein C-terminus binding 2263: 2161:10.1007/s11095-006-9043-0 1446:"Mouse PubMed Reference:" 1428:"Human PubMed Reference:" 1289: 1284: 1280: 1273: 1257: 1251:Chr 8: 107.76 – 107.77 Mb 1238: 1223: 1198: 1187: 1172: 1151: 1140: 1127: 1123: 1108: 1104: 1095: 1082: 1078: 1063: 1059: 1050: 1037: 1033: 1018: 1014: 1005: 990: 983: 979: 963: 830:ESCRT complex disassembly 588: 584: 567: 558: 549: 536: 485: 476: 423: 414: 384: 376: 372: 355: 342: 305: 284: 275: 271: 254: 241: 204: 181: 172: 168: 123: 120: 110: 103: 98: 71: 66: 49: 44: 39: 35: 26: 21: 1360:VPS4A has been shown to 1244:Chr 16: 69.31 – 69.33 Mb 770:endosomal vesicle fusion 509:dorsal tegmental nucleus 2086:10.1073/pnas.0502165102 1703:10.1242/jcs.114.13.2395 1579:10.1242/jcs.114.13.2395 2043:10.1074/jbc.M413968200 1887:10.1074/jbc.M301604200 1663:10.1073/pnas.160270997 1527:10.1006/jmbi.2001.4917 699:late endosome membrane 501:neural layer of retina 739:extracellular exosome 525:primary visual cortex 521:medial dorsal nucleus 455:middle temporal gyrus 198:Chromosome 16 (human) 2202:10.1128/JVI.00479-07 1481:10.1091/mbc.11.1.227 1334:amino acid sequence 805:vacuole organization 790:nucleus organization 427:gastrocnemius muscle 300:Chromosome 8 (mouse) 67:List of PDB id codes 40:Available structures 2077:2005PNAS..10213813S 1697:(Pt 13): 2395–404. 1654:2000PNAS...97.9543H 1573:(Pt 13): 2395–404. 1342:protein trafficking 910:endosomal transport 513:superior colliculus 497:seminiferous tubule 2304:This article on a 2001:(Pt 9): 1699–708. 1767:Cell Struct. Funct 1736:10.1042/BJ20020062 1085:ENSMUSG00000031913 955:midbody abscission 758:Biological process 652:Cellular component 628:hydrolase activity 603:nucleotide binding 596:Molecular function 459:right frontal lobe 2325: 2324: 2286: 2285: 2036:(13): 12799–809. 2008:10.1242/jcs.00998 1802:Am. J. Hum. Genet 1780:10.1247/csf.27.29 1300: 1299: 1296: 1295: 1269: 1268: 1234: 1233: 1213: 1212: 1183: 1182: 1162: 1161: 1136: 1135: 1117: 1116: 1091: 1090: 1072: 1071: 1046: 1045: 1027: 1026: 975: 974: 850:protein transport 810:vesicle uncoating 749:endosome membrane 694:vacuolar membrane 664:ESCRT III complex 580: 579: 576: 575: 545: 544: 532: 531: 470: 469: 431:cerebellar vermis 368: 367: 267: 266: 162:VPS4A - orthologs 94: 93: 90: 89: 50:Ortholog search: 2375: 2346: 2339: 2332: 2300: 2293: 2272: 2252: 2245: 2238: 2229: 2223: 2213: 2180: 2143: 2133: 2108: 2098: 2088: 2055: 2045: 2020: 2010: 1985: 1967: 1942: 1924: 1899: 1889: 1880:(40): 39104–13. 1864: 1835: 1825: 1792: 1782: 1757: 1747: 1730:(Pt 2): 349–53. 1714: 1685: 1675: 1665: 1631: 1591: 1590: 1562: 1556: 1555: 1548: 1539: 1538: 1509: 1503: 1502: 1492: 1460: 1454: 1453: 1442: 1436: 1435: 1424: 1418: 1408: 1397: 1387: 1282: 1281: 1253: 1246: 1229: 1217: 1208: 1192: 1188:RefSeq (protein) 1178: 1166: 1157: 1145: 1121: 1102: 1076: 1057: 1031: 1012: 981: 795:viral life cycle 586: 572: 563: 556: 541: 481: 479:Top expressed in 474: 463:endothelial cell 451:Brodmann area 23 419: 417:Top expressed in 412: 391: 374: 364: 351: 340: 325: 318: 312: 301: 289: 273: 263: 250: 239: 224: 217: 211: 200: 186: 170: 164: 115: 108: 85: 64: 58: 37: 36: 31: 19: 2383: 2382: 2378: 2377: 2376: 2374: 2373: 2372: 2353: 2352: 2351: 2350: 2289: 2287: 2282: 2279: 2273: 2259: 2256: 2226: 2196:(17): 9050–60. 2183: 2146: 2111: 2071:(39): 13813–8. 2058: 2023: 1988: 1945: 1902: 1867: 1838: 1795: 1760: 1717: 1688: 1634: 1604: 1600: 1598:Further reading 1595: 1594: 1564: 1563: 1559: 1550: 1549: 1542: 1511: 1510: 1506: 1462: 1461: 1457: 1444: 1443: 1439: 1426: 1425: 1421: 1409: 1400: 1388: 1379: 1374: 1358: 1322: 1291:View/Edit Mouse 1286:View/Edit Human 1249: 1242: 1239:Location (UCSC) 1225: 1204: 1200: 1174: 1153: 1066:ENSG00000132612 959: 753: 714:plasma membrane 647: 638:ATPase activity 623:protein binding 568: 537: 528: 523: 519: 515: 511: 507: 503: 499: 495: 491: 477: 466: 461: 457: 453: 449: 445: 441: 437: 435:muscle of thigh 433: 429: 415: 359: 346: 338: 328: 327: 326: 319: 299: 276:Gene location ( 258: 245: 237: 227: 226: 225: 218: 196: 173:Gene location ( 124: 111: 104: 73: 51: 17: 12: 11: 5: 2381: 2379: 2371: 2370: 2365: 2355: 2354: 2349: 2348: 2341: 2334: 2326: 2323: 2322: 2301: 2284: 2283: 2281: 2280: 2274: 2267: 2264: 2261: 2260: 2257: 2255: 2254: 2247: 2240: 2232: 2225: 2224: 2181: 2155:(8): 1687–95. 2144: 2109: 2056: 2021: 1986: 1943: 1900: 1865: 1836: 1814:10.1086/344580 1793: 1758: 1715: 1686: 1648:(17): 9543–8. 1632: 1601: 1599: 1596: 1593: 1592: 1557: 1540: 1504: 1455: 1437: 1419: 1398: 1376: 1375: 1373: 1370: 1357: 1354: 1321: 1318: 1298: 1297: 1294: 1293: 1288: 1278: 1277: 1271: 1270: 1267: 1266: 1264: 1262: 1255: 1254: 1247: 1240: 1236: 1235: 1232: 1231: 1221: 1220: 1214: 1211: 1210: 1196: 1195: 1189: 1185: 1184: 1181: 1180: 1170: 1169: 1163: 1160: 1159: 1149: 1148: 1142: 1138: 1137: 1134: 1133: 1125: 1124: 1118: 1115: 1114: 1106: 1105: 1099: 1093: 1092: 1089: 1088: 1080: 1079: 1073: 1070: 1069: 1061: 1060: 1054: 1048: 1047: 1044: 1043: 1035: 1034: 1028: 1025: 1024: 1016: 1015: 1009: 1003: 1002: 997: 992: 988: 987: 977: 976: 973: 972: 961: 960: 958: 957: 952: 947: 942: 937: 932: 927: 922: 917: 915:macroautophagy 912: 907: 902: 897: 892: 887: 882: 877: 872: 867: 862: 857: 852: 847: 842: 837: 832: 827: 822: 817: 812: 807: 802: 797: 792: 787: 782: 777: 772: 767: 761: 759: 755: 754: 752: 751: 746: 741: 736: 731: 726: 724:early endosome 721: 716: 711: 706: 701: 696: 691: 686: 681: 676: 671: 666: 661: 655: 653: 649: 648: 646: 645: 640: 635: 630: 625: 620: 615: 610: 605: 599: 597: 593: 592: 582: 581: 578: 577: 574: 573: 565: 564: 553: 547: 546: 543: 542: 534: 533: 530: 529: 527: 526: 522: 518: 517:pontine nuclei 514: 510: 506: 502: 498: 494: 490: 486: 483: 482: 471: 468: 467: 465: 464: 460: 456: 452: 448: 444: 440: 436: 432: 428: 424: 421: 420: 408: 407: 399: 388: 382: 381: 378:RNA expression 370: 369: 366: 365: 357: 353: 352: 344: 341: 336: 330: 329: 320: 313: 307: 303: 302: 297: 291: 290: 282: 281: 269: 268: 265: 264: 256: 252: 251: 243: 240: 235: 229: 228: 219: 212: 206: 202: 201: 194: 188: 187: 179: 178: 166: 165: 122: 118: 117: 109: 101: 100: 96: 95: 92: 91: 88: 87: 69: 68: 60: 59: 48: 42: 41: 33: 32: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 2380: 2369: 2366: 2364: 2361: 2360: 2358: 2347: 2342: 2340: 2335: 2333: 2328: 2327: 2321: 2319: 2315: 2311: 2310:chromosome 16 2307: 2302: 2299: 2295: 2290: 2277: 2271: 2266: 2262: 2253: 2248: 2246: 2241: 2239: 2234: 2233: 2230: 2221: 2217: 2212: 2207: 2203: 2199: 2195: 2191: 2187: 2182: 2178: 2174: 2170: 2166: 2162: 2158: 2154: 2150: 2145: 2141: 2137: 2132: 2127: 2124:(3): 333–46. 2123: 2119: 2115: 2110: 2106: 2102: 2097: 2092: 2087: 2082: 2078: 2074: 2070: 2066: 2062: 2057: 2053: 2049: 2044: 2039: 2035: 2031: 2030:J. Biol. Chem 2027: 2022: 2018: 2014: 2009: 2004: 2000: 1996: 1992: 1987: 1983: 1979: 1975: 1971: 1966: 1961: 1958:(6): 701–13. 1957: 1953: 1949: 1944: 1940: 1936: 1932: 1928: 1923: 1918: 1915:(6): 689–99. 1914: 1910: 1906: 1901: 1897: 1893: 1888: 1883: 1879: 1875: 1874:J. Biol. Chem 1871: 1866: 1862: 1858: 1854: 1850: 1846: 1842: 1837: 1833: 1829: 1824: 1819: 1815: 1811: 1808:(6): 1443–9. 1807: 1803: 1799: 1794: 1790: 1786: 1781: 1776: 1772: 1768: 1764: 1759: 1755: 1751: 1746: 1741: 1737: 1733: 1729: 1725: 1721: 1716: 1712: 1708: 1704: 1700: 1696: 1692: 1687: 1683: 1679: 1674: 1669: 1664: 1659: 1655: 1651: 1647: 1643: 1639: 1633: 1629: 1625: 1621: 1617: 1614:(1): 149–59. 1613: 1609: 1603: 1602: 1597: 1588: 1584: 1580: 1576: 1572: 1568: 1561: 1558: 1553: 1547: 1545: 1541: 1536: 1532: 1528: 1524: 1521:(3): 469–80. 1520: 1516: 1508: 1505: 1500: 1496: 1491: 1486: 1482: 1478: 1475:(1): 227–39. 1474: 1470: 1469:Mol Biol Cell 1466: 1459: 1456: 1451: 1447: 1441: 1438: 1433: 1429: 1423: 1420: 1416: 1412: 1407: 1405: 1403: 1399: 1395: 1391: 1386: 1384: 1382: 1378: 1371: 1369: 1367: 1363: 1355: 1353: 1351: 1350:chromosome 18 1347: 1346:chromosome 16 1343: 1339: 1335: 1331: 1327: 1319: 1317: 1315: 1312: 1308: 1304: 1292: 1287: 1283: 1279: 1276: 1272: 1265: 1263: 1260: 1256: 1252: 1248: 1245: 1241: 1237: 1230: 1228: 1222: 1218: 1215: 1209: 1207: 1203: 1197: 1193: 1190: 1186: 1179: 1177: 1171: 1167: 1164: 1158: 1156: 1150: 1146: 1143: 1141:RefSeq (mRNA) 1139: 1132: 1131: 1126: 1122: 1119: 1113: 1112: 1107: 1103: 1100: 1098: 1094: 1087: 1086: 1081: 1077: 1074: 1068: 1067: 1062: 1058: 1055: 1053: 1049: 1042: 1041: 1036: 1032: 1029: 1023: 1022: 1017: 1013: 1010: 1008: 1004: 1001: 998: 996: 993: 989: 986: 982: 978: 971: 967: 962: 956: 953: 951: 948: 946: 943: 941: 938: 936: 933: 931: 928: 926: 923: 921: 918: 916: 913: 911: 908: 906: 903: 901: 898: 896: 893: 891: 888: 886: 883: 881: 878: 876: 873: 871: 868: 866: 863: 861: 858: 856: 853: 851: 848: 846: 843: 841: 838: 836: 833: 831: 828: 826: 823: 821: 820:cell division 818: 816: 813: 811: 808: 806: 803: 801: 798: 796: 793: 791: 788: 786: 783: 781: 778: 776: 773: 771: 768: 766: 763: 762: 760: 757: 756: 750: 747: 745: 742: 740: 737: 735: 732: 730: 727: 725: 722: 720: 717: 715: 712: 710: 707: 705: 704:Flemming body 702: 700: 697: 695: 692: 690: 687: 685: 682: 680: 679:late endosome 677: 675: 672: 670: 667: 665: 662: 660: 657: 656: 654: 651: 650: 644: 641: 639: 636: 634: 631: 629: 626: 624: 621: 619: 616: 614: 611: 609: 606: 604: 601: 600: 598: 595: 594: 591: 590:Gene ontology 587: 583: 571: 566: 562: 557: 554: 552: 548: 540: 535: 524: 520: 516: 512: 508: 504: 500: 496: 492: 488: 487: 484: 480: 475: 472: 462: 458: 454: 450: 447:apex of heart 446: 443:parotid gland 442: 438: 434: 430: 426: 425: 422: 418: 413: 410: 409: 406: 404: 400: 398: 397: 393: 392: 389: 387: 383: 379: 375: 371: 363: 358: 354: 350: 345: 335: 331: 324: 317: 311: 304: 296: 292: 288: 283: 279: 274: 270: 262: 257: 253: 249: 244: 234: 230: 223: 216: 210: 203: 199: 193: 189: 185: 180: 176: 171: 167: 163: 159: 155: 151: 147: 143: 139: 135: 131: 127: 119: 114: 107: 102: 97: 86: 84: 80: 76: 70: 65: 62: 61: 57: 54: 47: 43: 38: 34: 30: 25: 20: 2318:expanding it 2303: 2288: 2275: 2193: 2189: 2152: 2148: 2121: 2117: 2068: 2064: 2033: 2029: 1998: 1994: 1955: 1951: 1912: 1908: 1877: 1873: 1847:(1): 47–59. 1844: 1840: 1805: 1801: 1773:(1): 29–37. 1770: 1766: 1727: 1723: 1694: 1690: 1645: 1641: 1611: 1607: 1570: 1566: 1560: 1518: 1514: 1507: 1472: 1468: 1458: 1449: 1440: 1431: 1422: 1359: 1356:Interactions 1323: 1310: 1302: 1301: 1224: 1199: 1173: 1152: 1128: 1109: 1083: 1064: 1038: 1019: 999: 994: 689:spindle pole 493:spermatocyte 401: 394: 360:107,772,387 347:107,757,854 121:External IDs 72: 2258:PDB gallery 1995:J. Cell Sci 1691:J. Cell Sci 1567:J. Cell Sci 1326:AAA protein 1206:NP_037377.1 633:ATP binding 339:8|8 D3 259:69,326,939 246:69,311,350 99:Identifiers 2357:Categories 2149:Pharm. Res 1724:Biochem. J 1515:J Mol Biol 1417:, May 2017 1396:, May 2017 1372:References 865:cell cycle 780:abscission 684:centrosome 405:(ortholog) 142:HomoloGene 2308:on human 1338:endosomal 1227:NP_569053 1202:NP_037377 1176:NM_126165 1155:NM_013245 985:Orthologs 845:transport 659:cytoplasm 489:spermatid 150:GeneCards 2220:17553870 2190:J. Virol 2169:16841193 2140:16730941 2118:Genomics 2105:16174732 2052:15632132 2017:15075231 1982:16894972 1974:14505570 1939:10733770 1931:14505569 1896:12860994 1861:12594041 1832:12417987 1789:11937716 1754:11931639 1711:11559748 1682:10931946 1628:10393249 1587:11559748 1535:11563910 1499:10637304 1413:– 1392:– 1362:interact 1330:paralogs 1320:Function 1275:Wikidata 964:Sources: 734:lysosome 709:membrane 674:endosome 2211:1951427 2177:2777033 2096:1236530 2073:Bibcode 1745:1222680 1650:Bibcode 1415:Ensembl 1394:Ensembl 1307:protein 1097:UniProt 1052:Ensembl 991:Species 970:QuickGO 744:nucleus 719:midbody 669:cytosol 380:pattern 238:16q22.1 138:1890520 106:Aliases 2218:  2208:  2175:  2167:  2138:  2103:  2093:  2050:  2015:  1980:  1972:  1937:  1929:  1894:  1859:  1830:  1823:378590 1820:  1787:  1752:  1742:  1709:  1680:  1670:  1626:  1585:  1533:  1497:  1487:  1366:CHMP1A 1261:search 1259:PubMed 1130:Q8VEJ9 1111:Q9UN37 1040:116733 1007:Entrez 551:BioGPS 130:609982 2312:is a 2173:S2CID 1978:S2CID 1935:S2CID 1673:16901 1490:14770 1364:with 1311:VPS4A 1305:is a 1021:27183 1000:Mouse 995:Human 966:Amigo 403:Mouse 396:Human 343:Start 278:Mouse 242:Start 175:Human 154:VPS4A 146:69132 113:VPS4A 22:VPS4A 2314:stub 2306:gene 2276:1yxr 2216:PMID 2165:PMID 2136:PMID 2101:PMID 2048:PMID 2013:PMID 1970:PMID 1952:Cell 1927:PMID 1909:Cell 1892:PMID 1857:PMID 1841:Gene 1828:PMID 1785:PMID 1750:PMID 1707:PMID 1678:PMID 1624:PMID 1608:Gene 1583:PMID 1531:PMID 1495:PMID 1314:gene 386:Bgee 334:Band 295:Chr. 233:Band 192:Chr. 126:OMIM 83:2K3W 79:2JQ9 75:1YXR 56:RCSB 53:PDBe 2206:PMC 2198:doi 2157:doi 2126:doi 2091:PMC 2081:doi 2069:102 2038:doi 2034:280 2003:doi 1999:117 1960:doi 1956:114 1917:doi 1913:114 1882:doi 1878:278 1849:doi 1845:305 1818:PMC 1810:doi 1775:doi 1740:PMC 1732:doi 1728:365 1699:doi 1695:114 1668:PMC 1658:doi 1616:doi 1612:234 1575:doi 1571:114 1523:doi 1519:312 1485:PMC 1477:doi 356:End 255:End 158:OMA 134:MGI 46:PDB 2359:: 2214:. 2204:. 2194:81 2192:. 2188:. 2171:. 2163:. 2153:23 2151:. 2134:. 2122:88 2120:. 2116:. 2099:. 2089:. 2079:. 2067:. 2063:. 2046:. 2032:. 2028:. 2011:. 1997:. 1993:. 1976:. 1968:. 1954:. 1950:. 1933:. 1925:. 1911:. 1907:. 1890:. 1876:. 1872:. 1855:. 1843:. 1826:. 1816:. 1806:71 1804:. 1800:. 1783:. 1771:27 1769:. 1765:. 1748:. 1738:. 1726:. 1722:. 1705:. 1693:. 1676:. 1666:. 1656:. 1646:97 1644:. 1640:. 1622:. 1610:. 1581:. 1569:. 1543:^ 1529:. 1517:. 1493:. 1483:. 1473:11 1471:. 1467:. 1448:. 1430:. 1401:^ 1380:^ 1368:. 1352:. 1316:. 968:/ 362:bp 349:bp 261:bp 248:bp 156:; 152:: 148:; 144:: 140:; 136:: 132:; 128:: 81:, 77:, 2345:e 2338:t 2331:v 2320:. 2251:e 2244:t 2237:v 2222:. 2200:: 2179:. 2159:: 2142:. 2128:: 2107:. 2083:: 2075:: 2054:. 2040:: 2019:. 2005:: 1984:. 1962:: 1941:. 1919:: 1898:. 1884:: 1863:. 1851:: 1834:. 1812:: 1791:. 1777:: 1756:. 1734:: 1713:. 1701:: 1684:. 1660:: 1652:: 1630:. 1618:: 1589:. 1577:: 1554:. 1537:. 1525:: 1501:. 1479:: 1452:. 1434:. 280:) 177:) 160::

Index


PDB
PDBe
RCSB
1YXR
2JQ9
2K3W
Aliases
VPS4A
OMIM
609982
MGI
1890520
HomoloGene
69132
GeneCards
VPS4A
OMA
VPS4A - orthologs
Human
Chromosome 16 (human)
Chr.
Chromosome 16 (human)
Chromosome 16 (human)
Genomic location for VPS4A
Genomic location for VPS4A
Band
bp
bp
Mouse

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