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VCAM-1

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cells can use VCAM-1 to adhere to the endothelium, VCAM-1 may participate in monocyte recruitment to atherosclerotic sites, and it is highly overexpressed in the inflamed brain. As a result, VCAM-1 is a potential
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Cybulsky M, Fries JW, Williams AJ, Sultan P, Eddy RL, Byers MG, Shows TB, Gimbrone MA Jr, Collins T (1991). "The human VCAM1 gene is assigned to chromosome 1p31-p32".
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VCAM-1 is also upregulated if vWF (Von Willebrand Factor) is given in knock-out (KO) ADMATS13 mice but not on mice without KO.
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Barreiro O, Yanez-Mo M, Serrador JM, Montoya MC, Vicente-Manzanares M, Tejedor R, Furthmayr H, Sanchez-Madrid F (Jun 2002).
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Upregulation of VCAM-1 in endothelial cells by cytokines occurs as a result of increased
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Le Besnerais M, Favre J, Denis CV, Mulder P, Martinet J, Nicol L, et al. (2016).
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National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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Proceedings of the National Academy of Sciences of the United States of America
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that encode different isoforms in humans. The gene product is a cell surface
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heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
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Eibl RH, Benoit M (2004). "Molecular resolution of cell adhesion forces".
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Yang ZX, Han ZB, Ji YR, Wang YW, Liang L, Chi Y, et al. (2013).
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cellular response to vascular endothelial growth factor stimulus
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alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex
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calcium-mediated signaling using intracellular calcium source
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Overview of all the structural information available in the
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CD106 also exists on the surface of some subpopulations of
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cell-cell adhesion in response to extracellular stimulus
412: 1617:"Entrez Gene: VCAM1 vascular cell adhesion molecule 1" 577: 143:, CD106, INCAM-100, vascular cell adhesion molecule 1 1361:, a type I membrane protein that is a member of the 4600: 4568: 4493: 4465: 4412: 4386: 4377: 4368: 4281: 4170: 4161: 3921: 3715: 3464: 3148: 2871: 2531: 2129: 1193: 1164: 1138: 1109: 1532: 1530: 1528: 1511: 1509: 1507: 1393:. It also functions in leukocyte-endothelial cell 1334:domains, and is expressed on both large and small 1877:"Targeting leukocyte integrins in human diseases" 359: 258: 1439:Primarily, the VCAM-1 protein is an endothelial 1397:, and it may play a role in the development of 27:Protein-coding gene in the species Homo sapiens 1628: 1626: 1537:GRCm38: Ensembl release 89: ENSMUSG00000027962 4135: 2098: 2007: 8: 1373:The VCAM-1 protein mediates the adhesion of 1516:GRCh38: Ensembl release 89: ENSG00000162692 827:positive regulation of T cell proliferation 777:interferon-gamma-mediated signaling pathway 4383: 4374: 4167: 4142: 4128: 4120: 2105: 2091: 2083: 2014: 2000: 1992: 1984:(Vascular cell adhesion protein 1) at the 942: 782:cellular response to tumor necrosis factor 612: 400: 299: 196: 90: 2122:list of human clusters of differentiation 1963:at the U.S. National Library of Medicine 1935: 1892: 1846: 1836: 1760: 1750: 1699: 1658: 1330:. The VCAM-1 gene contains six or seven 1322:, the superfamily of proteins including 2042:: Highly Hydrated Human VCAM-1 Fragment 2029: 1503: 45: 1420:(IL-1)) and through stabilization of 736:integral component of plasma membrane 364: 325: 320: 263: 222: 217: 7: 1428:(IL-4)). The promoter region of the 1786:IEE Proceedings - Nanobiotechnology 892:cytokine-mediated signaling pathway 1190: 1161: 1135: 1106: 1082: 1063: 1037: 1018: 992: 973: 582: 536:choroid plexus of fourth ventricle 500: 438: 417: 25: 1299:that in humans is encoded by the 1281:vascular cell adhesion molecule 1 917:cellular response to amyloid-beta 802:extracellular matrix organization 18:Vascular cell adhesion molecule-1 2062: 2047: 2032: 1432:gene contains functional tandem 1277:Vascular cell adhesion protein 1 726:external side of plasma membrane 586: 348: 341: 335: 312: 247: 240: 234: 209: 54: 1875:Yonekawa K, Harlan JM (2005). 1289:cluster of differentiation 106 907:cardiac neuron differentiation 897:heterotypic cell-cell adhesion 842:leukocyte tethering or rolling 812:response to lipopolysaccharide 757:response to ionizing radiation 656:integral component of membrane 640:cell adhesion molecule binding 630:primary amine oxidase activity 597:More reference expression data 566:More reference expression data 1: 1928:10.1158/0008-5472.CAN-07-1543 1455:). It has also been shown to 882:chronic inflammatory response 837:regulation of immune response 333: 232: 1819:Marcos-Contreras OA (2020). 1752:10.1371/journal.pone.0059354 832:membrane to membrane docking 752:leukocyte cell-cell adhesion 528:Epithelium of choroid plexus 4681:Genes on human chromosome 1 2118:clusters of differentiation 1414:tumor necrosis factor-alpha 822:acute inflammatory response 4702: 4608:Lymphocyte homing receptor 1320:immunoglobulin superfamily 1318:VCAM-1 is a member of the 36: 29: 2027: 1572:"Mouse PubMed Reference:" 1554:"Human PubMed Reference:" 1263: 1258: 1254: 1247: 1231: 1218:Chr 1: 100.72 – 100.74 Mb 1212: 1197: 1168: 1157: 1142: 1113: 1102: 1089: 1085: 1070: 1066: 1057: 1044: 1040: 1025: 1021: 1012: 999: 995: 980: 976: 967: 952: 945: 941: 925: 615: 611: 594: 585: 576: 563: 512: 503: 450: 441: 411: 403: 399: 382: 369: 332: 311: 302: 298: 281: 268: 231: 208: 199: 195: 150: 147: 137: 130: 125: 98: 93: 76: 71: 66: 62: 53: 48: 4640:Carcinoembryonic antigen 4494:Unconventional/ungrouped 1965:Medical Subject Headings 1342:cells are stimulated by 1306:. VCAM-1 functions as a 1225:Chr 3: 115.9 – 115.92 Mb 466:tendon of biceps brachii 4155:cell adhesion molecules 1838:10.1073/pnas.1912012117 1798:10.1049/ip-nbt:20040707 807:amine metabolic process 1475:mesenchymal stem cells 1412:(e.g., in response to 1308:cell adhesion molecule 852:B cell differentiation 482:metanephric glomerulus 4347:Glycoprotein IIb/IIIa 1651:10.1083/jcb.200112126 1591:Cytogenet. Cell Genet 1348:alternatively spliced 721:extracellular exosome 706:endoplasmic reticulum 516:stroma of bone marrow 4319:Macrophage-1 antigen 4305:Integrin alphaXbeta2 1403:rheumatoid arthritis 862:cell-matrix adhesion 797:response to zinc ion 787:response to nicotine 772:response to nutrient 366:3 G1|3 50.17 cM 327:Chromosome 3 (mouse) 225:Chromosome 1 (human) 94:List of PDB id codes 67:Available structures 4184:Myelin protein zero 4163:Calcium-independent 1894:10.1189/jlb.0804460 1743:2013PLoSO...859354Y 1453:smooth muscle cells 1395:signal transduction 872:response to ethanol 767:response to hypoxia 731:extracellular space 686:apical part of cell 1597:(3–4): 1850–1867. 1410:gene transcription 1047:ENSMUSG00000027962 887:cell-cell adhesion 745:Biological process 649:Cellular component 623:Molecular function 532:tibiofemoral joint 4668: 4667: 4596: 4595: 4564: 4563: 4370:Calcium-dependent 4364: 4363: 4151:Membrane proteins 4117: 4116: 2080: 2079: 1701:10.1111/jth.13439 1694:(10): 1917–1930. 1603:10.1159/000133735 1359:sialoglycoprotein 1274: 1273: 1270: 1269: 1243: 1242: 1208: 1207: 1187: 1186: 1153: 1152: 1132: 1131: 1098: 1097: 1079: 1078: 1053: 1052: 1034: 1033: 1008: 1007: 989: 988: 937: 936: 607: 606: 603: 602: 572: 571: 559: 558: 497: 496: 395: 394: 294: 293: 189:VCAM1 - orthologs 121: 120: 117: 116: 77:Ortholog search: 16:(Redirected from 4693: 4384: 4375: 4168: 4144: 4137: 4130: 4121: 2107: 2100: 2093: 2084: 2066: 2051: 2036: 2016: 2009: 2002: 1993: 1949: 1939: 1906: 1896: 1861: 1860: 1850: 1840: 1831:(7): 3405–3414. 1816: 1810: 1809: 1781: 1775: 1774: 1764: 1754: 1720: 1714: 1713: 1703: 1688:J Thromb Haemost 1679: 1673: 1672: 1662: 1630: 1621: 1620: 1613: 1607: 1606: 1586: 1580: 1579: 1568: 1562: 1561: 1550: 1544: 1534: 1523: 1513: 1328:T-cell receptors 1256: 1255: 1227: 1220: 1203: 1191: 1182: 1162: 1158:RefSeq (protein) 1148: 1136: 1127: 1107: 1083: 1064: 1038: 1019: 993: 974: 943: 635:integrin binding 613: 599: 590: 583: 568: 508: 506:Top expressed in 501: 454:cartilage tissue 446: 444:Top expressed in 439: 418: 401: 391: 378: 367: 352: 345: 339: 328: 316: 300: 290: 277: 266: 251: 244: 238: 227: 213: 197: 191: 142: 135: 112: 91: 85: 64: 63: 58: 46: 21: 4701: 4700: 4696: 4695: 4694: 4692: 4691: 4690: 4671: 4670: 4669: 4664: 4592: 4560: 4489: 4461: 4408: 4360: 4277: 4157: 4148: 4118: 4113: 3917: 3711: 3460: 3144: 2867: 2527: 2125: 2111: 2081: 2076: 2073: 2067: 2058: 2052: 2043: 2037: 2023: 2020: 1957: 1952: 1909: 1881:J. Leukoc. Biol 1874: 1870: 1868:Further reading 1865: 1864: 1818: 1817: 1813: 1783: 1782: 1778: 1722: 1721: 1717: 1681: 1680: 1676: 1632: 1631: 1624: 1615: 1614: 1610: 1588: 1587: 1583: 1570: 1569: 1565: 1552: 1551: 1547: 1535: 1526: 1514: 1505: 1500: 1483: 1399:atherosclerosis 1371: 1350:into two known 1338:only after the 1316: 1265:View/Edit Mouse 1260:View/Edit Human 1223: 1216: 1213:Location (UCSC) 1199: 1178: 1174: 1170: 1144: 1123: 1119: 1115: 1028:ENSG00000162692 921: 847:cell chemotaxis 740: 681:plasma membrane 661:Golgi apparatus 644: 595: 564: 555: 550: 546: 542: 538: 534: 530: 526: 522: 518: 504: 493: 488: 484: 480: 476: 472: 468: 464: 462:parietal pleura 460: 458:trabecular bone 456: 442: 386: 373: 365: 355: 354: 353: 346: 326: 303:Gene location ( 285: 272: 264: 254: 253: 252: 245: 223: 200:Gene location ( 151: 138: 131: 100: 78: 42: 35: 28: 23: 22: 15: 12: 11: 5: 4699: 4697: 4689: 4688: 4683: 4673: 4672: 4666: 4665: 4663: 4662: 4657: 4652: 4647: 4642: 4636: 4635: 4619: 4614: 4604: 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2261: 2260: 2255: 2250: 2245: 2235: 2230: 2225: 2224: 2223: 2213: 2208: 2203: 2198: 2193: 2192: 2191: 2186: 2181: 2171: 2166: 2165: 2164: 2159: 2154: 2149: 2144: 2133: 2131: 2127: 2126: 2112: 2110: 2109: 2102: 2095: 2087: 2078: 2077: 2075: 2074: 2068: 2061: 2059: 2053: 2046: 2044: 2038: 2031: 2028: 2025: 2024: 2021: 2019: 2018: 2011: 2004: 1996: 1990: 1989: 1968: 1956: 1955:External links 1953: 1951: 1950: 1922:(13): 6003–6. 1910:Wu TC (2007). 1907: 1871: 1869: 1866: 1863: 1862: 1811: 1776: 1715: 1674: 1645:(7): 1233–45. 1622: 1608: 1581: 1563: 1545: 1524: 1502: 1501: 1499: 1496: 1482: 1479: 1424:(mRNA) (e.g., 1370: 1367: 1363:Ig superfamily 1332:immunoglobulin 1315: 1312: 1279:also known as 1272: 1271: 1268: 1267: 1262: 1252: 1251: 1245: 1244: 1241: 1240: 1238: 1236: 1229: 1228: 1221: 1214: 1210: 1209: 1206: 1205: 1195: 1194: 1188: 1185: 1184: 1166: 1165: 1159: 1155: 1154: 1151: 1150: 1140: 1139: 1133: 1130: 1129: 1111: 1110: 1104: 1100: 1099: 1096: 1095: 1087: 1086: 1080: 1077: 1076: 1068: 1067: 1061: 1055: 1054: 1051: 1050: 1042: 1041: 1035: 1032: 1031: 1023: 1022: 1016: 1010: 1009: 1006: 1005: 997: 996: 990: 987: 986: 978: 977: 971: 965: 964: 959: 954: 950: 949: 939: 938: 935: 934: 923: 922: 920: 919: 914: 909: 904: 899: 894: 889: 884: 879: 874: 869: 864: 859: 854: 849: 844: 839: 834: 829: 824: 819: 814: 809: 804: 799: 794: 789: 784: 779: 774: 769: 764: 759: 754: 748: 746: 742: 741: 739: 738: 733: 728: 723: 718: 713: 708: 703: 701:early endosome 698: 693: 688: 683: 678: 673: 668: 663: 658: 652: 650: 646: 645: 643: 642: 637: 632: 626: 624: 620: 619: 609: 608: 605: 604: 601: 600: 592: 591: 580: 574: 573: 570: 569: 561: 560: 557: 556: 554: 553: 549: 545: 541: 540:left lung lobe 537: 533: 529: 525: 521: 517: 513: 510: 509: 498: 495: 494: 492: 491: 487: 486:synovial joint 483: 479: 475: 471: 467: 463: 459: 455: 451: 448: 447: 435: 434: 426: 415: 409: 408: 405:RNA expression 397: 396: 393: 392: 384: 380: 379: 371: 368: 363: 357: 356: 347: 340: 334: 330: 329: 324: 318: 317: 309: 308: 296: 295: 292: 291: 283: 279: 278: 270: 267: 262: 256: 255: 246: 239: 233: 229: 228: 221: 215: 214: 206: 205: 193: 192: 149: 145: 144: 136: 128: 127: 123: 122: 119: 118: 115: 114: 96: 95: 87: 86: 75: 69: 68: 60: 59: 51: 50: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 4698: 4687: 4684: 4682: 4679: 4678: 4676: 4661: 4658: 4656: 4653: 4651: 4648: 4646: 4643: 4641: 4638: 4637: 4633: 4629: 4625: 4624: 4620: 4618: 4615: 4613: 4609: 4606: 4605: 4603: 4599: 4589: 4586: 4584: 4581: 4579: 4576: 4575: 4573: 4571: 4567: 4557: 4554: 4552: 4549: 4547: 4544: 4542: 4539: 4537: 4534: 4532: 4529: 4527: 4524: 4522: 4519: 4517: 4514: 4512: 4509: 4507: 4504: 4502: 4499: 4498: 4496: 4492: 4486: 4483: 4481: 4478: 4476: 4473: 4472: 4470: 4468: 4467:Protocadherin 4464: 4457: 4453: 4449: 4445: 4442: 4439: 4435: 4431: 4427: 4423: 4420: 4419: 4417: 4415: 4411: 4405: 4402: 4400: 4397: 4395: 4392: 4391: 4389: 4385: 4382: 4380: 4376: 4373: 4371: 4367: 4356: 4352: 4348: 4345: 4342: 4338: 4334: 4331: 4328: 4324: 4320: 4317: 4314: 4310: 4306: 4303: 4300: 4296: 4292: 4289: 4288: 4286: 4284: 4280: 4272: 4269: 4267: 4264: 4262: 4259: 4257: 4254: 4252: 4249: 4247: 4244: 4243: 4242: 4239: 4235: 4232: 4230: 4227: 4225: 4222: 4220: 4217: 4216: 4215: 4212: 4210: 4207: 4205: 4202: 4199: 4195: 4191: 4188: 4185: 4181: 4178: 4177: 4175: 4173: 4169: 4166: 4164: 4160: 4156: 4152: 4145: 4140: 4138: 4133: 4131: 4126: 4125: 4122: 4110: 4107: 4105: 4102: 4100: 4097: 4095: 4092: 4090: 4087: 4085: 4082: 4080: 4077: 4075: 4072: 4070: 4067: 4065: 4062: 4060: 4057: 4055: 4052: 4050: 4047: 4045: 4042: 4040: 4037: 4035: 4032: 4030: 4027: 4025: 4022: 4020: 4017: 4015: 4012: 4010: 4007: 4005: 4002: 4000: 3997: 3995: 3992: 3990: 3987: 3985: 3982: 3980: 3977: 3975: 3972: 3970: 3967: 3965: 3962: 3960: 3957: 3955: 3952: 3950: 3947: 3945: 3942: 3940: 3937: 3935: 3932: 3930: 3927: 3926: 3924: 3920: 3914: 3911: 3909: 3906: 3904: 3901: 3899: 3896: 3894: 3891: 3889: 3886: 3884: 3881: 3879: 3876: 3874: 3871: 3869: 3866: 3864: 3861: 3859: 3856: 3854: 3851: 3849: 3846: 3844: 3841: 3839: 3836: 3834: 3831: 3829: 3826: 3824: 3821: 3819: 3816: 3814: 3811: 3809: 3806: 3804: 3801: 3799: 3796: 3794: 3791: 3789: 3786: 3784: 3781: 3779: 3776: 3774: 3771: 3769: 3766: 3764: 3761: 3759: 3756: 3754: 3751: 3749: 3746: 3744: 3741: 3739: 3736: 3734: 3731: 3729: 3726: 3724: 3721: 3720: 3718: 3714: 3708: 3705: 3703: 3699: 3696: 3694: 3691: 3689: 3686: 3684: 3681: 3679: 3676: 3674: 3671: 3669: 3666: 3664: 3661: 3659: 3656: 3654: 3651: 3647: 3644: 3642: 3639: 3638: 3637: 3634: 3632: 3629: 3627: 3624: 3622: 3619: 3617: 3614: 3612: 3609: 3607: 3604: 3602: 3599: 3597: 3594: 3592: 3589: 3587: 3584: 3582: 3579: 3577: 3574: 3572: 3569: 3566: 3563: 3561: 3557: 3554: 3552: 3549: 3545: 3542: 3540: 3537: 3536: 3535: 3532: 3530: 3527: 3523: 3520: 3518: 3515: 3514: 3513: 3510: 3508: 3505: 3503: 3500: 3498: 3495: 3493: 3490: 3488: 3485: 3483: 3480: 3478: 3475: 3473: 3470: 3469: 3467: 3463: 3457: 3454: 3452: 3449: 3447: 3444: 3442: 3439: 3437: 3434: 3432: 3429: 3427: 3424: 3422: 3419: 3417: 3414: 3412: 3409: 3407: 3404: 3402: 3399: 3397: 3394: 3392: 3389: 3387: 3384: 3382: 3379: 3377: 3374: 3370: 3367: 3365: 3362: 3361: 3360: 3357: 3355: 3352: 3350: 3347: 3345: 3342: 3338: 3335: 3333: 3330: 3328: 3325: 3324: 3323: 3320: 3318: 3315: 3313: 3310: 3308: 3305: 3303: 3300: 3296: 3293: 3291: 3288: 3287: 3286: 3283: 3281: 3278: 3276: 3273: 3271: 3268: 3266: 3263: 3261: 3258: 3256: 3253: 3249: 3246: 3244: 3241: 3240: 3239: 3236: 3233: 3230: 3228: 3225: 3223: 3220: 3218: 3215: 3213: 3209: 3206: 3204: 3201: 3197: 3194: 3192: 3189: 3187: 3184: 3183: 3182: 3179: 3177: 3174: 3172: 3169: 3167: 3164: 3162: 3159: 3157: 3154: 3153: 3151: 3147: 3141: 3138: 3136: 3133: 3131: 3128: 3126: 3123: 3121: 3118: 3116: 3113: 3111: 3108: 3106: 3103: 3101: 3098: 3096: 3093: 3091: 3088: 3086: 3083: 3081: 3078: 3076: 3073: 3071: 3068: 3066: 3063: 3061: 3058: 3056: 3053: 3051: 3048: 3046: 3043: 3041: 3038: 3036: 3033: 3031: 3028: 3026: 3023: 3021: 3018: 3014: 3011: 3009: 3006: 3005: 3004: 3001: 2997: 2994: 2992: 2989: 2988: 2987: 2984: 2982: 2979: 2977: 2974: 2972: 2969: 2967: 2964: 2962: 2959: 2957: 2954: 2952: 2949: 2947: 2944: 2942: 2939: 2937: 2934: 2932: 2929: 2927: 2924: 2920: 2917: 2915: 2912: 2911: 2910: 2907: 2905: 2902: 2900: 2897: 2895: 2892: 2890: 2887: 2885: 2882: 2880: 2877: 2876: 2874: 2870: 2864: 2861: 2859: 2856: 2854: 2851: 2849: 2846: 2844: 2841: 2839: 2836: 2834: 2831: 2829: 2826: 2824: 2820: 2817: 2815: 2812: 2810: 2807: 2805: 2802: 2800: 2797: 2795: 2792: 2788: 2785: 2783: 2780: 2778: 2775: 2773: 2770: 2768: 2765: 2763: 2760: 2759: 2758: 2755: 2753: 2750: 2748: 2745: 2743: 2740: 2738: 2735: 2733: 2730: 2726: 2723: 2721: 2718: 2717: 2716: 2713: 2711: 2708: 2706: 2703: 2701: 2698: 2696: 2693: 2691: 2688: 2686: 2683: 2681: 2678: 2676: 2673: 2669: 2666: 2664: 2661: 2659: 2656: 2654: 2651: 2649: 2646: 2644: 2641: 2640: 2639: 2636: 2632: 2629: 2627: 2624: 2622: 2619: 2618: 2617: 2614: 2612: 2609: 2605: 2602: 2600: 2597: 2595: 2592: 2591: 2590: 2587: 2585: 2582: 2580: 2577: 2575: 2572: 2570: 2567: 2565: 2562: 2560: 2557: 2555: 2552: 2550: 2547: 2545: 2542: 2540: 2537: 2536: 2534: 2530: 2524: 2521: 2517: 2514: 2512: 2509: 2507: 2504: 2502: 2499: 2497: 2494: 2492: 2489: 2488: 2487: 2484: 2482: 2479: 2477: 2474: 2472: 2469: 2467: 2464: 2462: 2459: 2457: 2454: 2450: 2447: 2445: 2442: 2440: 2437: 2435: 2432: 2431: 2430: 2427: 2425: 2422: 2420: 2417: 2415: 2412: 2410: 2407: 2405: 2402: 2400: 2397: 2395: 2392: 2390: 2387: 2385: 2382: 2378: 2375: 2373: 2370: 2369: 2368: 2365: 2363: 2360: 2358: 2355: 2353: 2350: 2348: 2345: 2343: 2340: 2338: 2335: 2333: 2330: 2328: 2325: 2323: 2320: 2318: 2315: 2313: 2310: 2308: 2305: 2303: 2300: 2298: 2295: 2291: 2288: 2286: 2283: 2282: 2281: 2278: 2276: 2273: 2271: 2268: 2266: 2263: 2259: 2256: 2254: 2251: 2249: 2246: 2244: 2241: 2240: 2239: 2236: 2234: 2231: 2229: 2226: 2222: 2219: 2218: 2217: 2214: 2212: 2209: 2207: 2204: 2202: 2199: 2197: 2194: 2190: 2187: 2185: 2182: 2180: 2177: 2176: 2175: 2172: 2170: 2167: 2163: 2160: 2158: 2155: 2153: 2150: 2148: 2145: 2143: 2140: 2139: 2138: 2135: 2134: 2132: 2128: 2123: 2119: 2115: 2108: 2103: 2101: 2096: 2094: 2089: 2088: 2085: 2071: 2065: 2060: 2056: 2050: 2045: 2041: 2035: 2030: 2026: 2017: 2012: 2010: 2005: 2003: 1998: 1997: 1994: 1987: 1983: 1982: 1977: 1973: 1969: 1966: 1962: 1959: 1958: 1954: 1947: 1943: 1938: 1933: 1929: 1925: 1921: 1917: 1913: 1908: 1904: 1900: 1895: 1890: 1887:(2): 129–40. 1886: 1882: 1878: 1873: 1872: 1867: 1858: 1854: 1849: 1844: 1839: 1834: 1830: 1826: 1822: 1815: 1812: 1807: 1803: 1799: 1795: 1792:(3): 128–32. 1791: 1787: 1780: 1777: 1772: 1768: 1763: 1758: 1753: 1748: 1744: 1740: 1737:(3): e59354. 1736: 1732: 1731: 1726: 1719: 1716: 1711: 1707: 1702: 1697: 1693: 1689: 1685: 1678: 1675: 1670: 1666: 1661: 1656: 1652: 1648: 1644: 1640: 1636: 1629: 1627: 1623: 1618: 1612: 1609: 1604: 1600: 1596: 1592: 1585: 1582: 1577: 1573: 1567: 1564: 1559: 1555: 1549: 1546: 1542: 1538: 1533: 1531: 1529: 1525: 1521: 1517: 1512: 1510: 1508: 1504: 1497: 1495: 1493: 1488: 1480: 1478: 1476: 1471: 1468: 1466: 1462: 1458: 1454: 1450: 1446: 1442: 1437: 1435: 1431: 1427: 1426:Interleukin-4 1423: 1422:messenger RNA 1419: 1418:interleukin-1 1415: 1411: 1406: 1404: 1400: 1396: 1392: 1388: 1384: 1380: 1376: 1368: 1366: 1364: 1360: 1356: 1353: 1349: 1345: 1341: 1337: 1336:blood vessels 1333: 1329: 1325: 1321: 1313: 1311: 1309: 1305: 1302: 1298: 1294: 1290: 1286: 1282: 1278: 1266: 1261: 1257: 1253: 1250: 1246: 1239: 1237: 1234: 1230: 1226: 1222: 1219: 1215: 1211: 1204: 1202: 1196: 1192: 1189: 1183: 1181: 1177: 1173: 1167: 1163: 1160: 1156: 1149: 1147: 1141: 1137: 1134: 1128: 1126: 1122: 1118: 1112: 1108: 1105: 1103:RefSeq (mRNA) 1101: 1094: 1093: 1088: 1084: 1081: 1075: 1074: 1069: 1065: 1062: 1060: 1056: 1049: 1048: 1043: 1039: 1036: 1030: 1029: 1024: 1020: 1017: 1015: 1011: 1004: 1003: 998: 994: 991: 985: 984: 979: 975: 972: 970: 966: 963: 960: 958: 955: 951: 948: 944: 940: 933: 929: 924: 918: 915: 913: 910: 908: 905: 903: 900: 898: 895: 893: 890: 888: 885: 883: 880: 878: 875: 873: 870: 868: 867:viral process 865: 863: 860: 858: 855: 853: 850: 848: 845: 843: 840: 838: 835: 833: 830: 828: 825: 823: 820: 818: 817:cell adhesion 815: 813: 810: 808: 805: 803: 800: 798: 795: 793: 790: 788: 785: 783: 780: 778: 775: 773: 770: 768: 765: 763: 760: 758: 755: 753: 750: 749: 747: 744: 743: 737: 734: 732: 729: 727: 724: 722: 719: 717: 714: 712: 709: 707: 704: 702: 699: 697: 694: 692: 689: 687: 684: 682: 679: 677: 674: 672: 669: 667: 664: 662: 659: 657: 654: 653: 651: 648: 647: 641: 638: 636: 633: 631: 628: 627: 625: 622: 621: 618: 617:Gene ontology 614: 610: 598: 593: 589: 584: 581: 579: 575: 567: 562: 551: 547: 543: 539: 535: 531: 527: 523: 519: 515: 514: 511: 507: 502: 499: 490:kidney tubule 489: 485: 481: 477: 473: 469: 465: 461: 457: 453: 452: 449: 445: 440: 437: 436: 433: 431: 427: 425: 424: 420: 419: 416: 414: 410: 406: 402: 398: 390: 385: 381: 377: 372: 362: 358: 351: 344: 338: 331: 323: 319: 315: 310: 306: 301: 297: 289: 284: 280: 276: 271: 261: 257: 250: 243: 237: 230: 226: 220: 216: 212: 207: 203: 198: 194: 190: 186: 182: 178: 174: 170: 166: 162: 158: 154: 146: 141: 134: 129: 124: 113: 111: 107: 103: 97: 92: 89: 88: 84: 81: 74: 70: 65: 61: 57: 52: 47: 44: 40: 33: 19: 4621: 4203: 3635: 3555: 3533: 3511: 3358: 3321: 3284: 3237: 3207: 3180: 3002: 2908: 2903: 2756: 2485: 2237: 2069: 2054: 2039: 1979: 1919: 1915: 1884: 1880: 1828: 1824: 1814: 1789: 1785: 1779: 1734: 1728: 1718: 1691: 1687: 1677: 1642: 1639:J. Cell Biol 1638: 1611: 1594: 1590: 1584: 1575: 1566: 1557: 1548: 1484: 1481:Pharmacology 1472: 1469: 1438: 1429: 1416:(TNF-α) and 1407: 1389:to vascular 1372: 1317: 1300: 1292: 1288: 1284: 1280: 1276: 1275: 1198: 1176:NP_001186763 1169: 1143: 1125:NM_001199834 1114: 1090: 1071: 1045: 1026: 1000: 981: 961: 956: 792:human ageing 696:cell surface 428: 421: 387:115,923,337 374:115,903,598 286:100,739,045 273:100,719,742 148:External IDs 99: 43: 4444:Desmocollin 2022:PDB gallery 1391:endothelium 1383:eosinophils 1375:lymphocytes 1355:transcripts 1340:endothelial 902:innervation 691:microvillus 548:human fetus 126:Identifiers 39:Cadmium-106 4675:Categories 4617:L-selectin 4588:P-selectin 4583:L-selectin 4578:E-selectin 4501:T-cadherin 4422:Desmoglein 4414:Desmosomal 2120:(see also 1916:Cancer Res 1543:, May 2017 1522:, May 2017 1498:References 1324:antibodies 716:sarcolemma 676:filopodium 478:glomerulus 432:(ortholog) 169:HomoloGene 4570:Selectins 4387:Classical 4379:Cadherins 4283:Integrins 4214:L1 family 1449:integrins 1387:basophils 1379:monocytes 1344:cytokines 1314:Structure 1201:NP_035823 1180:NP_542413 1172:NP_001069 1146:NM_011693 1121:NM_001078 1117:NM_080682 947:Orthologs 470:vena cava 177:GeneCards 4623:integrin 4172:IgSF CAM 2114:Proteins 2072:: VCAM-1 1946:17616653 1903:15548573 1857:32005712 1806:16475855 1771:23555021 1730:PLOS One 1710:27501520 1669:12082081 1539:– 1518:– 1494:target. 1487:melanoma 1485:Certain 1457:interact 1369:Function 1346:. It is 1249:Wikidata 926:Sources: 711:podosome 671:membrane 3922:301–350 3716:251–300 3668:CD240CE 3465:201–250 3149:151–200 2872:101–150 1986:PDBe-KB 1976:UniProt 1937:3179385 1848:7035611 1762:3595282 1739:Bibcode 1660:2173557 1541:Ensembl 1520:Ensembl 1477:(MSC). 1297:protein 1295:) is a 1059:UniProt 1014:Ensembl 953:Species 932:QuickGO 407:pattern 133:Aliases 4686:SIGLEC 4485:PCDH19 4480:PCDH15 4351:ITGA2B 4241:Nectin 4219:L1-CAM 4209:PE-CAM 4204:VCAM-1 3929:CD300A 3888:CDw293 3673:CD240D 3534:CD213a 3512:CDw210 3477:CD202b 3451:CDw199 3446:CDw198 3100:CD140b 2532:51–100 1981:P19320 1967:(MeSH) 1961:VCAM-1 1944:  1934:  1901:  1855:  1845:  1804:  1769:  1759:  1708:  1667:  1657:  1465:Moesin 1441:ligand 1385:, and 1285:VCAM-1 1235:search 1233:PubMed 1092:P29533 1073:P19320 969:Entrez 578:BioGPS 552:thymus 544:atrium 524:dermis 520:spleen 474:spleen 265:1p21.2 157:192225 4660:EpCAM 4655:CD146 4632:LFA-1 4628:VLA-4 4601:Other 4556:CDH10 4546:CDH17 4541:CDH16 4536:CDH15 4531:CDH12 4526:CDH11 4475:PCDH1 4355:ITGB3 4337:CD49d 4333:VLA-4 4323:CD11b 4309:CD11c 4295:CD11a 4291:LFA-1 4271:CD155 4266:CADM3 4261:CADM1 4256:PVRL3 4251:PVRL2 4246:PVRL1 4229:NFASC 4224:NRCAM 4180:N-CAM 4109:CD350 4104:CD349 4099:CD344 4094:CD340 4089:CD339 4084:CD338 4079:CD337 4074:CD336 4069:CD335 4064:CD334 4059:CD333 4054:CD332 4049:CD331 4044:CD329 4039:CD328 4034:CD327 4029:CD326 4024:CD325 4019:CD324 4014:CD322 4009:CD321 4004:CD320 3999:CD318 3994:CD317 3989:CD316 3984:CD315 3979:CD314 3974:CD312 3969:CD309 3964:CD307 3959:CD306 3954:CD305 3949:CD304 3944:CD303 3939:CD302 3934:CD301 3913:CD299 3908:CD298 3903:CD297 3898:CD295 3893:CD294 3883:CD292 3878:CD290 3873:CD289 3868:CD288 3863:CD286 3858:CD284 3853:CD283 3848:CD282 3843:CD281 3838:CD280 3833:CD279 3828:CD278 3823:CD276 3818:CD275 3813:CD274 3808:CD273 3803:CD272 3798:CD271 3793:CD269 3788:CD268 3783:CD267 3778:CD266 3773:CD265 3768:CD264 3763:CD263 3758:CD262 3753:CD261 3748:CD258 3743:CD257 3738:CD256 3733:CD254 3728:CD253 3723:CD252 3707:CD249 3702:CD248 3698:CD247 3693:CD246 3688:CD244 3683:CD243 3678:CD241 3663:CD239 3658:CD238 3653:CD236 3636:CD235 3631:CD234 3626:CD233 3621:CD230 3616:CD229 3611:CD228 3606:CD227 3601:CD226 3596:CD225 3591:CD224 3586:CD223 3581:CD222 3576:CD221 3571:CD220 3556:CD218 3551:CD217 3529:CD212 3507:CD209 3502:CD208 3497:CD207 3492:CD206 3487:CD205 3482:CD204 3472:CD201 3456:CD200 3441:CD197 3436:CD196 3431:CD195 3426:CD194 3421:CD193 3416:CD192 3411:CD191 3406:CD186 3401:CD185 3396:CD184 3391:CD183 3386:CD182 3381:CD181 3376:CD180 3359:CD179 3354:CD178 3349:CD177 3344:CD174 3322:CD172 3317:CD171 3312:CD170 3307:CD169 3302:CD168 3285:CD167 3280:CD166 3275:CD164 3270:CD163 3265:CD162 3260:CD161 3255:CD160 3238:CD159 3208:CD158 3203:CD157 3181:CD156 3176:CD155 3171:CD154 3166:CD153 3161:CD152 3156:CD151 3140:CD150 3135:CD148 3130:CD147 3125:CD146 3120:CD144 3115:CD143 3110:CD142 3105:CD141 3095:CD138 3090:CD137 3085:CD136 3080:CD135 3075:CD134 3070:CD133 3065:CD132 3060:CD131 3055:CD130 3050:CD129 3045:CD127 3040:CD126 3035:CD125 3030:CD124 3025:CD123 3020:CD122 3003:CD121 2986:CD120 2981:CD119 2976:CD118 2971:CD117 2966:CD116 2961:CD115 2956:CD114 2951:CD113 2946:CD112 2941:CD111 2936:CD110 2931:CD109 2926:CD108 2909:CD107 2904:CD106 2899:CD105 2894:CD104 2889:CD103 2884:CD102 2879:CD101 2863:CD100 1459:with 1445:VLA-4 1434:NF-κB 1430:VCAM1 1301:VCAM1 1293:CD106 1287:) or 1002:22329 962:Mouse 957:Human 928:Amigo 430:Mouse 423:Human 370:Start 305:Mouse 269:Start 202:Human 181:VCAM1 165:98926 140:VCAM1 49:VCAM1 4650:CD44 4645:CD24 4612:CD44 4551:CDH9 4521:CDH8 4516:CDH6 4511:CDH5 4506:CDH4 4456:DSC3 4452:DSC2 4448:DSC1 4438:DSG4 4434:DSG3 4430:DSG2 4426:DSG1 4404:CDH3 4399:CDH2 4394:CDH1 4341:CD29 4327:CD18 4313:CD18 4299:CD18 4234:CHL1 4190:ICAM 2858:CD99 2853:CD98 2848:CD97 2843:CD96 2838:CD95 2833:CD94 2828:CD93 2823:CD92 2819:CD91 2814:CD90 2809:CD89 2804:CD88 2799:CD87 2794:CD86 2757:CD85 2752:CD84 2747:CD83 2742:CD82 2737:CD81 2732:CD80 2715:CD79 2710:CD78 2705:CD74 2700:CD73 2695:CD72 2690:CD71 2685:CD70 2680:CD69 2675:CD68 2638:CD66 2616:CD64 2611:CD63 2589:CD62 2584:CD61 2579:CD59 2574:CD58 2569:CD57 2564:CD56 2559:CD55 2554:CD54 2549:CD53 2544:CD52 2539:CD51 2523:CD50 2486:CD49 2481:CD48 2476:CD47 2471:CD46 2466:CD45 2461:CD44 2456:CD43 2429:CD42 2424:CD41 2419:CD40 2414:CD39 2409:CD38 2404:CD37 2399:CD36 2394:CD35 2389:CD34 2384:CD33 2367:CD32 2362:CD31 2357:CD30 2352:CD29 2347:CD28 2342:CD27 2337:CD26 2332:CD25 2327:CD24 2322:CD23 2317:CD22 2312:CD21 2307:CD20 2302:CD19 2297:CD18 2280:CD16 2275:CD15 2270:CD14 2265:CD13 2238:CD11 2233:CD10 2130:1–50 2070:1vsc 2055:1vca 2040:1ij9 1974:for 1942:PMID 1899:PMID 1853:PMID 1802:PMID 1767:PMID 1706:PMID 1665:PMID 1492:drug 1463:and 1443:for 1401:and 1326:and 1304:gene 983:7412 413:Bgee 361:Band 322:Chr. 260:Band 219:Chr. 153:OMIM 110:1VSC 106:1VCA 102:1IJ9 83:RCSB 80:PDBe 32:WNCD 2228:CD9 2216:CD8 2211:CD7 2206:CD6 2201:CD5 2196:CD4 2174:CD3 2169:CD2 2142:a-c 2137:CD1 1972:PDB 1932:PMC 1924:doi 1889:doi 1843:PMC 1833:doi 1829:117 1794:doi 1790:151 1757:PMC 1747:doi 1696:doi 1655:PMC 1647:doi 1643:157 1599:doi 1461:EZR 1352:RNA 383:End 282:End 185:OMA 173:838 161:MGI 73:PDB 4677:: 4630:, 4610:: 4454:, 4450:, 4436:, 4432:, 4428:, 4196:, 4153:: 3700:- 2821:- 2162:1E 2157:1D 2152:1B 2147:1A 2116:: 1978:: 1940:. 1930:. 1920:67 1918:. 1914:. 1897:. 1885:77 1883:. 1879:. 1851:. 1841:. 1827:. 1823:. 1800:. 1788:. 1765:. 1755:. 1745:. 1733:. 1727:. 1704:. 1692:14 1690:. 1686:. 1663:. 1653:. 1641:. 1637:. 1625:^ 1595:58 1593:. 1574:. 1556:. 1527:^ 1506:^ 1467:. 1405:. 1381:, 1377:, 1365:. 1310:. 930:/ 389:bp 376:bp 288:bp 275:bp 183:; 179:: 175:; 171:: 167:; 163:: 159:; 155:: 108:, 104:, 4634:) 4626:( 4458:) 4446:( 4440:) 4424:( 4357:) 4353:+ 4349:( 4343:) 4339:+ 4335:( 4329:) 4325:+ 4321:( 4315:) 4311:+ 4307:( 4301:) 4297:+ 4293:( 4200:) 4198:5 4194:1 4192:( 4186:) 4182:( 4143:e 4136:t 4129:v 3646:b 3641:a 3567:) 3565:b 3560:a 3558:( 3544:2 3539:1 3522:b 3517:a 3369:b 3364:a 3337:g 3332:b 3327:a 3295:b 3290:a 3248:c 3243:a 3234:) 3232:k 3227:i 3222:e 3217:d 3212:a 3210:( 3196:c 3191:b 3186:a 3013:b 3008:a 2996:b 2991:a 2919:b 2914:a 2787:k 2782:j 2777:h 2772:e 2767:d 2762:a 2725:b 2720:a 2668:f 2663:e 2658:d 2653:c 2648:b 2643:a 2631:C 2626:B 2621:A 2604:P 2599:L 2594:E 2516:f 2511:e 2506:d 2501:c 2496:b 2491:a 2449:d 2444:c 2439:b 2434:a 2377:B 2372:A 2290:B 2285:A 2258:d 2253:c 2248:b 2243:a 2221:a 2189:ε 2184:δ 2179:γ 2124:) 2106:e 2099:t 2092:v 2015:e 2008:t 2001:v 1988:. 1948:. 1926:: 1905:. 1891:: 1859:. 1835:: 1808:. 1796:: 1773:. 1749:: 1741:: 1735:8 1712:. 1698:: 1671:. 1649:: 1619:. 1605:. 1601:: 1578:. 1560:. 1291:( 1283:( 307:) 204:) 187:: 41:. 34:. 20:)

Index

Vascular cell adhesion molecule-1
WNCD
Cadmium-106

PDB
PDBe
RCSB
1IJ9
1VCA
1VSC
Aliases
VCAM1
OMIM
192225
MGI
98926
HomoloGene
838
GeneCards
VCAM1
OMA
VCAM1 - orthologs
Human
Chromosome 1 (human)
Chr.
Chromosome 1 (human)
Chromosome 1 (human)
Genomic location for VCAM1
Genomic location for VCAM1
Band

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