337:
314:
211:
236:
2049:
588:
343:
242:
56:
2034:
2064:
82:
1489:
cells can use VCAM-1 to adhere to the endothelium, VCAM-1 may participate in monocyte recruitment to atherosclerotic sites, and it is highly overexpressed in the inflamed brain. As a result, VCAM-1 is a potential
2048:
2965:
2104:
4141:
350:
249:
1589:
Cybulsky M, Fries JW, Williams AJ, Sultan P, Eddy RL, Byers MG, Shows TB, Gimbrone MA Jr, Collins T (1991). "The human VCAM1 gene is assigned to chromosome 1p31-p32".
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1001:
982:
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2121:
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172:
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3528:
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2013:
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4053:
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336:
1224:
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4028:
313:
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1635:"Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes"
1616:
4189:
3832:
3326:
3012:
1540:
1519:
1470:
VCAM-1 is also upregulated if vWF (Von
Willebrand Factor) is given in knock-out (KO) ADMATS13 mice but not on mice without KO.
2033:
3471:
3007:
1633:
Barreiro O, Yanez-Mo M, Serrador JM, Montoya MC, Vicente-Manzanares M, Tejedor R, Furthmayr H, Sanchez-Madrid F (Jun 2002).
1536:
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349:
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2057:: CRYSTAL STRUCTURE OF AN INTEGRIN-BINDING FRAGMENT OF VASCULAR CELL ADHESION MOLECULE-1 AT 1.8 ANGSTROMS RESOLUTION
1684:"Assessment of endothelial damage and cardiac injury in a mouse model mimicking thrombotic thrombocytopenic purpura"
4607:
3692:
2117:
1362:
1319:
342:
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2006:
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1354:
1046:
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3706:
1027:
4369:
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4154:
3049:
3044:
3039:
3029:
2336:
2264:
1307:
1821:"Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood–brain barrier"
4346:
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2311:
1474:
4318:
4304:
3630:
3343:
1999:
1738:
1402:
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139:
1725:"CD106 identifies a subpopulation of mesenchymal stem cells with unique immunomodulatory properties"
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Upregulation of VCAM-1 in endothelial cells by cytokines occurs as a result of increased
1742:
1436:(nuclear factor-kappa B) sites. The sustained expression of VCAM-1 lasts over 24 hours.
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1936:
1911:
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Le
Besnerais M, Favre J, Denis CV, Mulder P, Martinet J, Nicol L, et al. (2016).
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30:"CD106" redirects here. For the radio station formerly known as "CD106 the Wolf", see
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National Center for
Biotechnology Information, U.S. National Library of Medicine
1558:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1390:
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38:
1825:
Proceedings of the
National Academy of Sciences of the United States of America
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that encode different isoforms in humans. The gene product is a cell surface
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heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
1784:
Eibl RH, Benoit M (2004). "Molecular resolution of cell adhesion forces".
1650:
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1985:
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1912:"The role of vascular cell adhesion molecule-1 in tumor immune evasion"
1296:
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37:"Cd106" redirects here. For the isotope of cadmium (Cd-106 or Cd), see
1700:
1683:
1602:
1451:. VCAM-1 expression has also been observed in other cell types (e.g.,
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Yang ZX, Han ZB, Ji YR, Wang YW, Liang L, Chi Y, et al. (2013).
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1491:
1303:
857:
cellular response to vascular endothelial growth factor stimulus
156:
31:
4123:
2086:
1995:
666:
alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex
596:
3615:
2227:
2215:
2210:
2205:
2195:
2168:
2136:
1991:
1447:(Very Late Antigen-4 or integrin α4β1) of the β1 subfamily of
1351:
877:
calcium-mediated signaling using intracellular calcium source
1970:
Overview of all the structural information available in the
1473:
CD106 also exists on the surface of some subpopulations of
912:
cell-cell adhesion in response to extracellular stimulus
412:
1617:"Entrez Gene: VCAM1 vascular cell adhesion molecule 1"
577:
143:, CD106, INCAM-100, vascular cell adhesion molecule 1
1361:, a type I membrane protein that is a member of the
4600:
4568:
4493:
4465:
4412:
4386:
4377:
4368:
4281:
4170:
4161:
3921:
3715:
3464:
3148:
2871:
2531:
2129:
1193:
1164:
1138:
1109:
1532:
1530:
1528:
1511:
1509:
1507:
1393:. It also functions in leukocyte-endothelial cell
1334:domains, and is expressed on both large and small
1877:"Targeting leukocyte integrins in human diseases"
359:
258:
1439:Primarily, the VCAM-1 protein is an endothelial
1397:, and it may play a role in the development of
27:Protein-coding gene in the species Homo sapiens
1628:
1626:
1537:GRCm38: Ensembl release 89: ENSMUSG00000027962
4135:
2098:
2007:
8:
1373:The VCAM-1 protein mediates the adhesion of
1516:GRCh38: Ensembl release 89: ENSG00000162692
827:positive regulation of T cell proliferation
777:interferon-gamma-mediated signaling pathway
4383:
4374:
4167:
4142:
4128:
4120:
2105:
2091:
2083:
2014:
2000:
1992:
1984:(Vascular cell adhesion protein 1) at the
942:
782:cellular response to tumor necrosis factor
612:
400:
299:
196:
90:
2122:list of human clusters of differentiation
1963:at the U.S. National Library of Medicine
1935:
1892:
1846:
1836:
1760:
1750:
1699:
1658:
1330:. The VCAM-1 gene contains six or seven
1322:, the superfamily of proteins including
2042:: Highly Hydrated Human VCAM-1 Fragment
2029:
1503:
45:
1420:(IL-1)) and through stabilization of
736:integral component of plasma membrane
364:
325:
320:
263:
222:
217:
7:
1428:(IL-4)). The promoter region of the
1786:IEE Proceedings - Nanobiotechnology
892:cytokine-mediated signaling pathway
1190:
1161:
1135:
1106:
1082:
1063:
1037:
1018:
992:
973:
582:
536:choroid plexus of fourth ventricle
500:
438:
417:
25:
1299:that in humans is encoded by the
1281:vascular cell adhesion molecule 1
917:cellular response to amyloid-beta
802:extracellular matrix organization
18:Vascular cell adhesion molecule-1
2062:
2047:
2032:
1432:gene contains functional tandem
1277:Vascular cell adhesion protein 1
726:external side of plasma membrane
586:
348:
341:
335:
312:
247:
240:
234:
209:
54:
1875:Yonekawa K, Harlan JM (2005).
1289:cluster of differentiation 106
907:cardiac neuron differentiation
897:heterotypic cell-cell adhesion
842:leukocyte tethering or rolling
812:response to lipopolysaccharide
757:response to ionizing radiation
656:integral component of membrane
640:cell adhesion molecule binding
630:primary amine oxidase activity
597:More reference expression data
566:More reference expression data
1:
1928:10.1158/0008-5472.CAN-07-1543
1455:). It has also been shown to
882:chronic inflammatory response
837:regulation of immune response
333:
232:
1819:Marcos-Contreras OA (2020).
1752:10.1371/journal.pone.0059354
832:membrane to membrane docking
752:leukocyte cell-cell adhesion
528:Epithelium of choroid plexus
4681:Genes on human chromosome 1
2118:clusters of differentiation
1414:tumor necrosis factor-alpha
822:acute inflammatory response
4702:
4608:Lymphocyte homing receptor
1320:immunoglobulin superfamily
1318:VCAM-1 is a member of the
36:
29:
2027:
1572:"Mouse PubMed Reference:"
1554:"Human PubMed Reference:"
1263:
1258:
1254:
1247:
1231:
1218:Chr 1: 100.72 – 100.74 Mb
1212:
1197:
1168:
1157:
1142:
1113:
1102:
1089:
1085:
1070:
1066:
1057:
1044:
1040:
1025:
1021:
1012:
999:
995:
980:
976:
967:
952:
945:
941:
925:
615:
611:
594:
585:
576:
563:
512:
503:
450:
441:
411:
403:
399:
382:
369:
332:
311:
302:
298:
281:
268:
231:
208:
199:
195:
150:
147:
137:
130:
125:
98:
93:
76:
71:
66:
62:
53:
48:
4640:Carcinoembryonic antigen
4494:Unconventional/ungrouped
1965:Medical Subject Headings
1342:cells are stimulated by
1306:. VCAM-1 functions as a
1225:Chr 3: 115.9 – 115.92 Mb
466:tendon of biceps brachii
4155:cell adhesion molecules
1838:10.1073/pnas.1912012117
1798:10.1049/ip-nbt:20040707
807:amine metabolic process
1475:mesenchymal stem cells
1412:(e.g., in response to
1308:cell adhesion molecule
852:B cell differentiation
482:metanephric glomerulus
4347:Glycoprotein IIb/IIIa
1651:10.1083/jcb.200112126
1591:Cytogenet. Cell Genet
1348:alternatively spliced
721:extracellular exosome
706:endoplasmic reticulum
516:stroma of bone marrow
4319:Macrophage-1 antigen
4305:Integrin alphaXbeta2
1403:rheumatoid arthritis
862:cell-matrix adhesion
797:response to zinc ion
787:response to nicotine
772:response to nutrient
366:3 G1|3 50.17 cM
327:Chromosome 3 (mouse)
225:Chromosome 1 (human)
94:List of PDB id codes
67:Available structures
4184:Myelin protein zero
4163:Calcium-independent
1894:10.1189/jlb.0804460
1743:2013PLoSO...859354Y
1453:smooth muscle cells
1395:signal transduction
872:response to ethanol
767:response to hypoxia
731:extracellular space
686:apical part of cell
1597:(3–4): 1850–1867.
1410:gene transcription
1047:ENSMUSG00000027962
887:cell-cell adhesion
745:Biological process
649:Cellular component
623:Molecular function
532:tibiofemoral joint
4668:
4667:
4596:
4595:
4564:
4563:
4370:Calcium-dependent
4364:
4363:
4151:Membrane proteins
4117:
4116:
2080:
2079:
1701:10.1111/jth.13439
1694:(10): 1917–1930.
1603:10.1159/000133735
1359:sialoglycoprotein
1274:
1273:
1270:
1269:
1243:
1242:
1208:
1207:
1187:
1186:
1153:
1152:
1132:
1131:
1098:
1097:
1079:
1078:
1053:
1052:
1034:
1033:
1008:
1007:
989:
988:
937:
936:
607:
606:
603:
602:
572:
571:
559:
558:
497:
496:
395:
394:
294:
293:
189:VCAM1 - orthologs
121:
120:
117:
116:
77:Ortholog search:
16:(Redirected from
4693:
4384:
4375:
4168:
4144:
4137:
4130:
4121:
2107:
2100:
2093:
2084:
2066:
2051:
2036:
2016:
2009:
2002:
1993:
1949:
1939:
1906:
1896:
1861:
1860:
1850:
1840:
1831:(7): 3405–3414.
1816:
1810:
1809:
1781:
1775:
1774:
1764:
1754:
1720:
1714:
1713:
1703:
1688:J Thromb Haemost
1679:
1673:
1672:
1662:
1630:
1621:
1620:
1613:
1607:
1606:
1586:
1580:
1579:
1568:
1562:
1561:
1550:
1544:
1534:
1523:
1513:
1328:T-cell receptors
1256:
1255:
1227:
1220:
1203:
1191:
1182:
1162:
1158:RefSeq (protein)
1148:
1136:
1127:
1107:
1083:
1064:
1038:
1019:
993:
974:
943:
635:integrin binding
613:
599:
590:
583:
568:
508:
506:Top expressed in
501:
454:cartilage tissue
446:
444:Top expressed in
439:
418:
401:
391:
378:
367:
352:
345:
339:
328:
316:
300:
290:
277:
266:
251:
244:
238:
227:
213:
197:
191:
142:
135:
112:
91:
85:
64:
63:
58:
46:
21:
4701:
4700:
4696:
4695:
4694:
4692:
4691:
4690:
4671:
4670:
4669:
4664:
4592:
4560:
4489:
4461:
4408:
4360:
4277:
4157:
4148:
4118:
4113:
3917:
3711:
3460:
3144:
2867:
2527:
2125:
2111:
2081:
2076:
2073:
2067:
2058:
2052:
2043:
2037:
2023:
2020:
1957:
1952:
1909:
1881:J. Leukoc. Biol
1874:
1870:
1868:Further reading
1865:
1864:
1818:
1817:
1813:
1783:
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1778:
1722:
1721:
1717:
1681:
1680:
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1610:
1588:
1587:
1583:
1570:
1569:
1565:
1552:
1551:
1547:
1535:
1526:
1514:
1505:
1500:
1483:
1399:atherosclerosis
1371:
1350:into two known
1338:only after the
1316:
1265:View/Edit Mouse
1260:View/Edit Human
1223:
1216:
1213:Location (UCSC)
1199:
1178:
1174:
1170:
1144:
1123:
1119:
1115:
1028:ENSG00000162692
921:
847:cell chemotaxis
740:
681:plasma membrane
661:Golgi apparatus
644:
595:
564:
555:
550:
546:
542:
538:
534:
530:
526:
522:
518:
504:
493:
488:
484:
480:
476:
472:
468:
464:
462:parietal pleura
460:
458:trabecular bone
456:
442:
386:
373:
365:
355:
354:
353:
346:
326:
303:Gene location (
285:
272:
264:
254:
253:
252:
245:
223:
200:Gene location (
151:
138:
131:
100:
78:
42:
35:
28:
23:
22:
15:
12:
11:
5:
4699:
4697:
4689:
4688:
4683:
4673:
4672:
4666:
4665:
4663:
4662:
4657:
4652:
4647:
4642:
4636:
4635:
4619:
4614:
4604:
4602:
4598:
4597:
4594:
4593:
4591:
4590:
4585:
4580:
4574:
4572:
4566:
4565:
4562:
4561:
4559:
4558:
4553:
4548:
4543:
4538:
4533:
4528:
4523:
4518:
4513:
4508:
4503:
4497:
4495:
4491:
4490:
4488:
4487:
4482:
4477:
4471:
4469:
4463:
4462:
4460:
4459:
4441:
4418:
4416:
4410:
4409:
4407:
4406:
4401:
4396:
4390:
4388:
4381:
4372:
4366:
4365:
4362:
4361:
4359:
4358:
4344:
4330:
4316:
4302:
4287:
4285:
4279:
4278:
4276:
4275:
4274:
4273:
4268:
4263:
4258:
4253:
4248:
4238:
4237:
4236:
4231:
4226:
4221:
4211:
4206:
4201:
4187:
4176:
4174:
4165:
4159:
4158:
4149:
4147:
4146:
4139:
4132:
4124:
4115:
4114:
4112:
4111:
4106:
4101:
4096:
4091:
4086:
4081:
4076:
4071:
4066:
4061:
4056:
4051:
4046:
4041:
4036:
4031:
4026:
4021:
4016:
4011:
4006:
4001:
3996:
3991:
3986:
3981:
3976:
3971:
3966:
3961:
3956:
3951:
3946:
3941:
3936:
3931:
3925:
3923:
3919:
3918:
3916:
3915:
3910:
3905:
3900:
3895:
3890:
3885:
3880:
3875:
3870:
3865:
3860:
3855:
3850:
3845:
3840:
3835:
3830:
3825:
3820:
3815:
3810:
3805:
3800:
3795:
3790:
3785:
3780:
3775:
3770:
3765:
3760:
3755:
3750:
3745:
3740:
3735:
3730:
3725:
3719:
3717:
3713:
3712:
3710:
3709:
3704:
3695:
3690:
3685:
3680:
3675:
3670:
3665:
3660:
3655:
3650:
3649:
3648:
3643:
3633:
3628:
3623:
3618:
3613:
3608:
3603:
3598:
3593:
3588:
3583:
3578:
3573:
3568:
3562:
3553:
3548:
3547:
3546:
3541:
3531:
3526:
3525:
3524:
3519:
3509:
3504:
3499:
3494:
3489:
3484:
3479:
3474:
3468:
3466:
3462:
3461:
3459:
3458:
3453:
3448:
3443:
3438:
3433:
3428:
3423:
3418:
3413:
3408:
3403:
3398:
3393:
3388:
3383:
3378:
3373:
3372:
3371:
3366:
3356:
3351:
3346:
3341:
3340:
3339:
3334:
3329:
3319:
3314:
3309:
3304:
3299:
3298:
3297:
3292:
3282:
3277:
3272:
3267:
3262:
3257:
3252:
3251:
3250:
3245:
3235:
3229:
3224:
3219:
3214:
3205:
3200:
3199:
3198:
3193:
3188:
3178:
3173:
3168:
3163:
3158:
3152:
3150:
3146:
3145:
3143:
3142:
3137:
3132:
3127:
3122:
3117:
3112:
3107:
3102:
3097:
3092:
3087:
3082:
3077:
3072:
3067:
3062:
3057:
3052:
3047:
3042:
3037:
3032:
3027:
3022:
3017:
3016:
3015:
3010:
3000:
2999:
2998:
2993:
2983:
2978:
2973:
2968:
2963:
2958:
2953:
2948:
2943:
2938:
2933:
2928:
2923:
2922:
2921:
2916:
2906:
2901:
2896:
2891:
2886:
2881:
2875:
2873:
2869:
2868:
2866:
2865:
2860:
2855:
2850:
2845:
2840:
2835:
2830:
2825:
2816:
2811:
2806:
2801:
2796:
2791:
2790:
2789:
2784:
2779:
2774:
2769:
2764:
2754:
2749:
2744:
2739:
2734:
2729:
2728:
2727:
2722:
2712:
2707:
2702:
2697:
2692:
2687:
2682:
2677:
2672:
2671:
2670:
2665:
2660:
2655:
2650:
2645:
2635:
2634:
2633:
2628:
2623:
2613:
2608:
2607:
2606:
2601:
2596:
2586:
2581:
2576:
2571:
2566:
2561:
2556:
2551:
2546:
2541:
2535:
2533:
2529:
2528:
2526:
2525:
2520:
2519:
2518:
2513:
2508:
2503:
2498:
2493:
2483:
2478:
2473:
2468:
2463:
2458:
2453:
2452:
2451:
2446:
2441:
2436:
2426:
2421:
2416:
2411:
2406:
2401:
2396:
2391:
2386:
2381:
2380:
2379:
2374:
2364:
2359:
2354:
2349:
2344:
2339:
2334:
2329:
2324:
2319:
2314:
2309:
2304:
2299:
2294:
2293:
2292:
2287:
2277:
2272:
2267:
2262:
2261:
2260:
2255:
2250:
2245:
2235:
2230:
2225:
2224:
2223:
2213:
2208:
2203:
2198:
2193:
2192:
2191:
2186:
2181:
2171:
2166:
2165:
2164:
2159:
2154:
2149:
2144:
2133:
2131:
2127:
2126:
2112:
2110:
2109:
2102:
2095:
2087:
2078:
2077:
2075:
2074:
2068:
2061:
2059:
2053:
2046:
2044:
2038:
2031:
2028:
2025:
2024:
2021:
2019:
2018:
2011:
2004:
1996:
1990:
1989:
1968:
1956:
1955:External links
1953:
1951:
1950:
1922:(13): 6003–6.
1910:Wu TC (2007).
1907:
1871:
1869:
1866:
1863:
1862:
1811:
1776:
1715:
1674:
1645:(7): 1233–45.
1622:
1608:
1581:
1563:
1545:
1524:
1502:
1501:
1499:
1496:
1482:
1479:
1424:(mRNA) (e.g.,
1370:
1367:
1363:Ig superfamily
1332:immunoglobulin
1315:
1312:
1279:also known as
1272:
1271:
1268:
1267:
1262:
1252:
1251:
1245:
1244:
1241:
1240:
1238:
1236:
1229:
1228:
1221:
1214:
1210:
1209:
1206:
1205:
1195:
1194:
1188:
1185:
1184:
1166:
1165:
1159:
1155:
1154:
1151:
1150:
1140:
1139:
1133:
1130:
1129:
1111:
1110:
1104:
1100:
1099:
1096:
1095:
1087:
1086:
1080:
1077:
1076:
1068:
1067:
1061:
1055:
1054:
1051:
1050:
1042:
1041:
1035:
1032:
1031:
1023:
1022:
1016:
1010:
1009:
1006:
1005:
997:
996:
990:
987:
986:
978:
977:
971:
965:
964:
959:
954:
950:
949:
939:
938:
935:
934:
923:
922:
920:
919:
914:
909:
904:
899:
894:
889:
884:
879:
874:
869:
864:
859:
854:
849:
844:
839:
834:
829:
824:
819:
814:
809:
804:
799:
794:
789:
784:
779:
774:
769:
764:
759:
754:
748:
746:
742:
741:
739:
738:
733:
728:
723:
718:
713:
708:
703:
701:early endosome
698:
693:
688:
683:
678:
673:
668:
663:
658:
652:
650:
646:
645:
643:
642:
637:
632:
626:
624:
620:
619:
609:
608:
605:
604:
601:
600:
592:
591:
580:
574:
573:
570:
569:
561:
560:
557:
556:
554:
553:
549:
545:
541:
540:left lung lobe
537:
533:
529:
525:
521:
517:
513:
510:
509:
498:
495:
494:
492:
491:
487:
486:synovial joint
483:
479:
475:
471:
467:
463:
459:
455:
451:
448:
447:
435:
434:
426:
415:
409:
408:
405:RNA expression
397:
396:
393:
392:
384:
380:
379:
371:
368:
363:
357:
356:
347:
340:
334:
330:
329:
324:
318:
317:
309:
308:
296:
295:
292:
291:
283:
279:
278:
270:
267:
262:
256:
255:
246:
239:
233:
229:
228:
221:
215:
214:
206:
205:
193:
192:
149:
145:
144:
136:
128:
127:
123:
122:
119:
118:
115:
114:
96:
95:
87:
86:
75:
69:
68:
60:
59:
51:
50:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
4698:
4687:
4684:
4682:
4679:
4678:
4676:
4661:
4658:
4656:
4653:
4651:
4648:
4646:
4643:
4641:
4638:
4637:
4633:
4629:
4625:
4624:
4620:
4618:
4615:
4613:
4609:
4606:
4605:
4603:
4599:
4589:
4586:
4584:
4581:
4579:
4576:
4575:
4573:
4571:
4567:
4557:
4554:
4552:
4549:
4547:
4544:
4542:
4539:
4537:
4534:
4532:
4529:
4527:
4524:
4522:
4519:
4517:
4514:
4512:
4509:
4507:
4504:
4502:
4499:
4498:
4496:
4492:
4486:
4483:
4481:
4478:
4476:
4473:
4472:
4470:
4468:
4467:Protocadherin
4464:
4457:
4453:
4449:
4445:
4442:
4439:
4435:
4431:
4427:
4423:
4420:
4419:
4417:
4415:
4411:
4405:
4402:
4400:
4397:
4395:
4392:
4391:
4389:
4385:
4382:
4380:
4376:
4373:
4371:
4367:
4356:
4352:
4348:
4345:
4342:
4338:
4334:
4331:
4328:
4324:
4320:
4317:
4314:
4310:
4306:
4303:
4300:
4296:
4292:
4289:
4288:
4286:
4284:
4280:
4272:
4269:
4267:
4264:
4262:
4259:
4257:
4254:
4252:
4249:
4247:
4244:
4243:
4242:
4239:
4235:
4232:
4230:
4227:
4225:
4222:
4220:
4217:
4216:
4215:
4212:
4210:
4207:
4205:
4202:
4199:
4195:
4191:
4188:
4185:
4181:
4178:
4177:
4175:
4173:
4169:
4166:
4164:
4160:
4156:
4152:
4145:
4140:
4138:
4133:
4131:
4126:
4125:
4122:
4110:
4107:
4105:
4102:
4100:
4097:
4095:
4092:
4090:
4087:
4085:
4082:
4080:
4077:
4075:
4072:
4070:
4067:
4065:
4062:
4060:
4057:
4055:
4052:
4050:
4047:
4045:
4042:
4040:
4037:
4035:
4032:
4030:
4027:
4025:
4022:
4020:
4017:
4015:
4012:
4010:
4007:
4005:
4002:
4000:
3997:
3995:
3992:
3990:
3987:
3985:
3982:
3980:
3977:
3975:
3972:
3970:
3967:
3965:
3962:
3960:
3957:
3955:
3952:
3950:
3947:
3945:
3942:
3940:
3937:
3935:
3932:
3930:
3927:
3926:
3924:
3920:
3914:
3911:
3909:
3906:
3904:
3901:
3899:
3896:
3894:
3891:
3889:
3886:
3884:
3881:
3879:
3876:
3874:
3871:
3869:
3866:
3864:
3861:
3859:
3856:
3854:
3851:
3849:
3846:
3844:
3841:
3839:
3836:
3834:
3831:
3829:
3826:
3824:
3821:
3819:
3816:
3814:
3811:
3809:
3806:
3804:
3801:
3799:
3796:
3794:
3791:
3789:
3786:
3784:
3781:
3779:
3776:
3774:
3771:
3769:
3766:
3764:
3761:
3759:
3756:
3754:
3751:
3749:
3746:
3744:
3741:
3739:
3736:
3734:
3731:
3729:
3726:
3724:
3721:
3720:
3718:
3714:
3708:
3705:
3703:
3699:
3696:
3694:
3691:
3689:
3686:
3684:
3681:
3679:
3676:
3674:
3671:
3669:
3666:
3664:
3661:
3659:
3656:
3654:
3651:
3647:
3644:
3642:
3639:
3638:
3637:
3634:
3632:
3629:
3627:
3624:
3622:
3619:
3617:
3614:
3612:
3609:
3607:
3604:
3602:
3599:
3597:
3594:
3592:
3589:
3587:
3584:
3582:
3579:
3577:
3574:
3572:
3569:
3566:
3563:
3561:
3557:
3554:
3552:
3549:
3545:
3542:
3540:
3537:
3536:
3535:
3532:
3530:
3527:
3523:
3520:
3518:
3515:
3514:
3513:
3510:
3508:
3505:
3503:
3500:
3498:
3495:
3493:
3490:
3488:
3485:
3483:
3480:
3478:
3475:
3473:
3470:
3469:
3467:
3463:
3457:
3454:
3452:
3449:
3447:
3444:
3442:
3439:
3437:
3434:
3432:
3429:
3427:
3424:
3422:
3419:
3417:
3414:
3412:
3409:
3407:
3404:
3402:
3399:
3397:
3394:
3392:
3389:
3387:
3384:
3382:
3379:
3377:
3374:
3370:
3367:
3365:
3362:
3361:
3360:
3357:
3355:
3352:
3350:
3347:
3345:
3342:
3338:
3335:
3333:
3330:
3328:
3325:
3324:
3323:
3320:
3318:
3315:
3313:
3310:
3308:
3305:
3303:
3300:
3296:
3293:
3291:
3288:
3287:
3286:
3283:
3281:
3278:
3276:
3273:
3271:
3268:
3266:
3263:
3261:
3258:
3256:
3253:
3249:
3246:
3244:
3241:
3240:
3239:
3236:
3233:
3230:
3228:
3225:
3223:
3220:
3218:
3215:
3213:
3209:
3206:
3204:
3201:
3197:
3194:
3192:
3189:
3187:
3184:
3183:
3182:
3179:
3177:
3174:
3172:
3169:
3167:
3164:
3162:
3159:
3157:
3154:
3153:
3151:
3147:
3141:
3138:
3136:
3133:
3131:
3128:
3126:
3123:
3121:
3118:
3116:
3113:
3111:
3108:
3106:
3103:
3101:
3098:
3096:
3093:
3091:
3088:
3086:
3083:
3081:
3078:
3076:
3073:
3071:
3068:
3066:
3063:
3061:
3058:
3056:
3053:
3051:
3048:
3046:
3043:
3041:
3038:
3036:
3033:
3031:
3028:
3026:
3023:
3021:
3018:
3014:
3011:
3009:
3006:
3005:
3004:
3001:
2997:
2994:
2992:
2989:
2988:
2987:
2984:
2982:
2979:
2977:
2974:
2972:
2969:
2967:
2964:
2962:
2959:
2957:
2954:
2952:
2949:
2947:
2944:
2942:
2939:
2937:
2934:
2932:
2929:
2927:
2924:
2920:
2917:
2915:
2912:
2911:
2910:
2907:
2905:
2902:
2900:
2897:
2895:
2892:
2890:
2887:
2885:
2882:
2880:
2877:
2876:
2874:
2870:
2864:
2861:
2859:
2856:
2854:
2851:
2849:
2846:
2844:
2841:
2839:
2836:
2834:
2831:
2829:
2826:
2824:
2820:
2817:
2815:
2812:
2810:
2807:
2805:
2802:
2800:
2797:
2795:
2792:
2788:
2785:
2783:
2780:
2778:
2775:
2773:
2770:
2768:
2765:
2763:
2760:
2759:
2758:
2755:
2753:
2750:
2748:
2745:
2743:
2740:
2738:
2735:
2733:
2730:
2726:
2723:
2721:
2718:
2717:
2716:
2713:
2711:
2708:
2706:
2703:
2701:
2698:
2696:
2693:
2691:
2688:
2686:
2683:
2681:
2678:
2676:
2673:
2669:
2666:
2664:
2661:
2659:
2656:
2654:
2651:
2649:
2646:
2644:
2641:
2640:
2639:
2636:
2632:
2629:
2627:
2624:
2622:
2619:
2618:
2617:
2614:
2612:
2609:
2605:
2602:
2600:
2597:
2595:
2592:
2591:
2590:
2587:
2585:
2582:
2580:
2577:
2575:
2572:
2570:
2567:
2565:
2562:
2560:
2557:
2555:
2552:
2550:
2547:
2545:
2542:
2540:
2537:
2536:
2534:
2530:
2524:
2521:
2517:
2514:
2512:
2509:
2507:
2504:
2502:
2499:
2497:
2494:
2492:
2489:
2488:
2487:
2484:
2482:
2479:
2477:
2474:
2472:
2469:
2467:
2464:
2462:
2459:
2457:
2454:
2450:
2447:
2445:
2442:
2440:
2437:
2435:
2432:
2431:
2430:
2427:
2425:
2422:
2420:
2417:
2415:
2412:
2410:
2407:
2405:
2402:
2400:
2397:
2395:
2392:
2390:
2387:
2385:
2382:
2378:
2375:
2373:
2370:
2369:
2368:
2365:
2363:
2360:
2358:
2355:
2353:
2350:
2348:
2345:
2343:
2340:
2338:
2335:
2333:
2330:
2328:
2325:
2323:
2320:
2318:
2315:
2313:
2310:
2308:
2305:
2303:
2300:
2298:
2295:
2291:
2288:
2286:
2283:
2282:
2281:
2278:
2276:
2273:
2271:
2268:
2266:
2263:
2259:
2256:
2254:
2251:
2249:
2246:
2244:
2241:
2240:
2239:
2236:
2234:
2231:
2229:
2226:
2222:
2219:
2218:
2217:
2214:
2212:
2209:
2207:
2204:
2202:
2199:
2197:
2194:
2190:
2187:
2185:
2182:
2180:
2177:
2176:
2175:
2172:
2170:
2167:
2163:
2160:
2158:
2155:
2153:
2150:
2148:
2145:
2143:
2140:
2139:
2138:
2135:
2134:
2132:
2128:
2123:
2119:
2115:
2108:
2103:
2101:
2096:
2094:
2089:
2088:
2085:
2071:
2065:
2060:
2056:
2050:
2045:
2041:
2035:
2030:
2026:
2017:
2012:
2010:
2005:
2003:
1998:
1997:
1994:
1987:
1983:
1982:
1977:
1973:
1969:
1966:
1962:
1959:
1958:
1954:
1947:
1943:
1938:
1933:
1929:
1925:
1921:
1917:
1913:
1908:
1904:
1900:
1895:
1890:
1887:(2): 129–40.
1886:
1882:
1878:
1873:
1872:
1867:
1858:
1854:
1849:
1844:
1839:
1834:
1830:
1826:
1822:
1815:
1812:
1807:
1803:
1799:
1795:
1792:(3): 128–32.
1791:
1787:
1780:
1777:
1772:
1768:
1763:
1758:
1753:
1748:
1744:
1740:
1737:(3): e59354.
1736:
1732:
1731:
1726:
1719:
1716:
1711:
1707:
1702:
1697:
1693:
1689:
1685:
1678:
1675:
1670:
1666:
1661:
1656:
1652:
1648:
1644:
1640:
1636:
1629:
1627:
1623:
1618:
1612:
1609:
1604:
1600:
1596:
1592:
1585:
1582:
1577:
1573:
1567:
1564:
1559:
1555:
1549:
1546:
1542:
1538:
1533:
1531:
1529:
1525:
1521:
1517:
1512:
1510:
1508:
1504:
1497:
1495:
1493:
1488:
1480:
1478:
1476:
1471:
1468:
1466:
1462:
1458:
1454:
1450:
1446:
1442:
1437:
1435:
1431:
1427:
1426:Interleukin-4
1423:
1422:messenger RNA
1419:
1418:interleukin-1
1415:
1411:
1406:
1404:
1400:
1396:
1392:
1388:
1384:
1380:
1376:
1368:
1366:
1364:
1360:
1356:
1353:
1349:
1345:
1341:
1337:
1336:blood vessels
1333:
1329:
1325:
1321:
1313:
1311:
1309:
1305:
1302:
1298:
1294:
1290:
1286:
1282:
1278:
1266:
1261:
1257:
1253:
1250:
1246:
1239:
1237:
1234:
1230:
1226:
1222:
1219:
1215:
1211:
1204:
1202:
1196:
1192:
1189:
1183:
1181:
1177:
1173:
1167:
1163:
1160:
1156:
1149:
1147:
1141:
1137:
1134:
1128:
1126:
1122:
1118:
1112:
1108:
1105:
1103:RefSeq (mRNA)
1101:
1094:
1093:
1088:
1084:
1081:
1075:
1074:
1069:
1065:
1062:
1060:
1056:
1049:
1048:
1043:
1039:
1036:
1030:
1029:
1024:
1020:
1017:
1015:
1011:
1004:
1003:
998:
994:
991:
985:
984:
979:
975:
972:
970:
966:
963:
960:
958:
955:
951:
948:
944:
940:
933:
929:
924:
918:
915:
913:
910:
908:
905:
903:
900:
898:
895:
893:
890:
888:
885:
883:
880:
878:
875:
873:
870:
868:
867:viral process
865:
863:
860:
858:
855:
853:
850:
848:
845:
843:
840:
838:
835:
833:
830:
828:
825:
823:
820:
818:
817:cell adhesion
815:
813:
810:
808:
805:
803:
800:
798:
795:
793:
790:
788:
785:
783:
780:
778:
775:
773:
770:
768:
765:
763:
760:
758:
755:
753:
750:
749:
747:
744:
743:
737:
734:
732:
729:
727:
724:
722:
719:
717:
714:
712:
709:
707:
704:
702:
699:
697:
694:
692:
689:
687:
684:
682:
679:
677:
674:
672:
669:
667:
664:
662:
659:
657:
654:
653:
651:
648:
647:
641:
638:
636:
633:
631:
628:
627:
625:
622:
621:
618:
617:Gene ontology
614:
610:
598:
593:
589:
584:
581:
579:
575:
567:
562:
551:
547:
543:
539:
535:
531:
527:
523:
519:
515:
514:
511:
507:
502:
499:
490:kidney tubule
489:
485:
481:
477:
473:
469:
465:
461:
457:
453:
452:
449:
445:
440:
437:
436:
433:
431:
427:
425:
424:
420:
419:
416:
414:
410:
406:
402:
398:
390:
385:
381:
377:
372:
362:
358:
351:
344:
338:
331:
323:
319:
315:
310:
306:
301:
297:
289:
284:
280:
276:
271:
261:
257:
250:
243:
237:
230:
226:
220:
216:
212:
207:
203:
198:
194:
190:
186:
182:
178:
174:
170:
166:
162:
158:
154:
146:
141:
134:
129:
124:
113:
111:
107:
103:
97:
92:
89:
88:
84:
81:
74:
70:
65:
61:
57:
52:
47:
44:
40:
33:
19:
4621:
4203:
3635:
3555:
3533:
3511:
3358:
3321:
3284:
3237:
3207:
3180:
3002:
2908:
2903:
2756:
2485:
2237:
2069:
2054:
2039:
1979:
1919:
1915:
1884:
1880:
1828:
1824:
1814:
1789:
1785:
1779:
1734:
1728:
1718:
1691:
1687:
1677:
1642:
1639:J. Cell Biol
1638:
1611:
1594:
1590:
1584:
1575:
1566:
1557:
1548:
1484:
1481:Pharmacology
1472:
1469:
1438:
1429:
1416:(TNF-α) and
1407:
1389:to vascular
1372:
1317:
1300:
1292:
1288:
1284:
1280:
1276:
1275:
1198:
1176:NP_001186763
1169:
1143:
1125:NM_001199834
1114:
1090:
1071:
1045:
1026:
1000:
981:
961:
956:
792:human ageing
696:cell surface
428:
421:
387:115,923,337
374:115,903,598
286:100,739,045
273:100,719,742
148:External IDs
99:
43:
4444:Desmocollin
2022:PDB gallery
1391:endothelium
1383:eosinophils
1375:lymphocytes
1355:transcripts
1340:endothelial
902:innervation
691:microvillus
548:human fetus
126:Identifiers
39:Cadmium-106
4675:Categories
4617:L-selectin
4588:P-selectin
4583:L-selectin
4578:E-selectin
4501:T-cadherin
4422:Desmoglein
4414:Desmosomal
2120:(see also
1916:Cancer Res
1543:, May 2017
1522:, May 2017
1498:References
1324:antibodies
716:sarcolemma
676:filopodium
478:glomerulus
432:(ortholog)
169:HomoloGene
4570:Selectins
4387:Classical
4379:Cadherins
4283:Integrins
4214:L1 family
1449:integrins
1387:basophils
1379:monocytes
1344:cytokines
1314:Structure
1201:NP_035823
1180:NP_542413
1172:NP_001069
1146:NM_011693
1121:NM_001078
1117:NM_080682
947:Orthologs
470:vena cava
177:GeneCards
4623:integrin
4172:IgSF CAM
2114:Proteins
2072:: VCAM-1
1946:17616653
1903:15548573
1857:32005712
1806:16475855
1771:23555021
1730:PLOS One
1710:27501520
1669:12082081
1539:–
1518:–
1494:target.
1487:melanoma
1485:Certain
1457:interact
1369:Function
1346:. It is
1249:Wikidata
926:Sources:
711:podosome
671:membrane
3922:301–350
3716:251–300
3668:CD240CE
3465:201–250
3149:151–200
2872:101–150
1986:PDBe-KB
1976:UniProt
1937:3179385
1848:7035611
1762:3595282
1739:Bibcode
1660:2173557
1541:Ensembl
1520:Ensembl
1477:(MSC).
1297:protein
1295:) is a
1059:UniProt
1014:Ensembl
953:Species
932:QuickGO
407:pattern
133:Aliases
4686:SIGLEC
4485:PCDH19
4480:PCDH15
4351:ITGA2B
4241:Nectin
4219:L1-CAM
4209:PE-CAM
4204:VCAM-1
3929:CD300A
3888:CDw293
3673:CD240D
3534:CD213a
3512:CDw210
3477:CD202b
3451:CDw199
3446:CDw198
3100:CD140b
2532:51–100
1981:P19320
1967:(MeSH)
1961:VCAM-1
1944:
1934:
1901:
1855:
1845:
1804:
1769:
1759:
1708:
1667:
1657:
1465:Moesin
1441:ligand
1385:, and
1285:VCAM-1
1235:search
1233:PubMed
1092:P29533
1073:P19320
969:Entrez
578:BioGPS
552:thymus
544:atrium
524:dermis
520:spleen
474:spleen
265:1p21.2
157:192225
4660:EpCAM
4655:CD146
4632:LFA-1
4628:VLA-4
4601:Other
4556:CDH10
4546:CDH17
4541:CDH16
4536:CDH15
4531:CDH12
4526:CDH11
4475:PCDH1
4355:ITGB3
4337:CD49d
4333:VLA-4
4323:CD11b
4309:CD11c
4295:CD11a
4291:LFA-1
4271:CD155
4266:CADM3
4261:CADM1
4256:PVRL3
4251:PVRL2
4246:PVRL1
4229:NFASC
4224:NRCAM
4180:N-CAM
4109:CD350
4104:CD349
4099:CD344
4094:CD340
4089:CD339
4084:CD338
4079:CD337
4074:CD336
4069:CD335
4064:CD334
4059:CD333
4054:CD332
4049:CD331
4044:CD329
4039:CD328
4034:CD327
4029:CD326
4024:CD325
4019:CD324
4014:CD322
4009:CD321
4004:CD320
3999:CD318
3994:CD317
3989:CD316
3984:CD315
3979:CD314
3974:CD312
3969:CD309
3964:CD307
3959:CD306
3954:CD305
3949:CD304
3944:CD303
3939:CD302
3934:CD301
3913:CD299
3908:CD298
3903:CD297
3898:CD295
3893:CD294
3883:CD292
3878:CD290
3873:CD289
3868:CD288
3863:CD286
3858:CD284
3853:CD283
3848:CD282
3843:CD281
3838:CD280
3833:CD279
3828:CD278
3823:CD276
3818:CD275
3813:CD274
3808:CD273
3803:CD272
3798:CD271
3793:CD269
3788:CD268
3783:CD267
3778:CD266
3773:CD265
3768:CD264
3763:CD263
3758:CD262
3753:CD261
3748:CD258
3743:CD257
3738:CD256
3733:CD254
3728:CD253
3723:CD252
3707:CD249
3702:CD248
3698:CD247
3693:CD246
3688:CD244
3683:CD243
3678:CD241
3663:CD239
3658:CD238
3653:CD236
3636:CD235
3631:CD234
3626:CD233
3621:CD230
3616:CD229
3611:CD228
3606:CD227
3601:CD226
3596:CD225
3591:CD224
3586:CD223
3581:CD222
3576:CD221
3571:CD220
3556:CD218
3551:CD217
3529:CD212
3507:CD209
3502:CD208
3497:CD207
3492:CD206
3487:CD205
3482:CD204
3472:CD201
3456:CD200
3441:CD197
3436:CD196
3431:CD195
3426:CD194
3421:CD193
3416:CD192
3411:CD191
3406:CD186
3401:CD185
3396:CD184
3391:CD183
3386:CD182
3381:CD181
3376:CD180
3359:CD179
3354:CD178
3349:CD177
3344:CD174
3322:CD172
3317:CD171
3312:CD170
3307:CD169
3302:CD168
3285:CD167
3280:CD166
3275:CD164
3270:CD163
3265:CD162
3260:CD161
3255:CD160
3238:CD159
3208:CD158
3203:CD157
3181:CD156
3176:CD155
3171:CD154
3166:CD153
3161:CD152
3156:CD151
3140:CD150
3135:CD148
3130:CD147
3125:CD146
3120:CD144
3115:CD143
3110:CD142
3105:CD141
3095:CD138
3090:CD137
3085:CD136
3080:CD135
3075:CD134
3070:CD133
3065:CD132
3060:CD131
3055:CD130
3050:CD129
3045:CD127
3040:CD126
3035:CD125
3030:CD124
3025:CD123
3020:CD122
3003:CD121
2986:CD120
2981:CD119
2976:CD118
2971:CD117
2966:CD116
2961:CD115
2956:CD114
2951:CD113
2946:CD112
2941:CD111
2936:CD110
2931:CD109
2926:CD108
2909:CD107
2904:CD106
2899:CD105
2894:CD104
2889:CD103
2884:CD102
2879:CD101
2863:CD100
1459:with
1445:VLA-4
1434:NF-κB
1430:VCAM1
1301:VCAM1
1293:CD106
1287:) or
1002:22329
962:Mouse
957:Human
928:Amigo
430:Mouse
423:Human
370:Start
305:Mouse
269:Start
202:Human
181:VCAM1
165:98926
140:VCAM1
49:VCAM1
4650:CD44
4645:CD24
4612:CD44
4551:CDH9
4521:CDH8
4516:CDH6
4511:CDH5
4506:CDH4
4456:DSC3
4452:DSC2
4448:DSC1
4438:DSG4
4434:DSG3
4430:DSG2
4426:DSG1
4404:CDH3
4399:CDH2
4394:CDH1
4341:CD29
4327:CD18
4313:CD18
4299:CD18
4234:CHL1
4190:ICAM
2858:CD99
2853:CD98
2848:CD97
2843:CD96
2838:CD95
2833:CD94
2828:CD93
2823:CD92
2819:CD91
2814:CD90
2809:CD89
2804:CD88
2799:CD87
2794:CD86
2757:CD85
2752:CD84
2747:CD83
2742:CD82
2737:CD81
2732:CD80
2715:CD79
2710:CD78
2705:CD74
2700:CD73
2695:CD72
2690:CD71
2685:CD70
2680:CD69
2675:CD68
2638:CD66
2616:CD64
2611:CD63
2589:CD62
2584:CD61
2579:CD59
2574:CD58
2569:CD57
2564:CD56
2559:CD55
2554:CD54
2549:CD53
2544:CD52
2539:CD51
2523:CD50
2486:CD49
2481:CD48
2476:CD47
2471:CD46
2466:CD45
2461:CD44
2456:CD43
2429:CD42
2424:CD41
2419:CD40
2414:CD39
2409:CD38
2404:CD37
2399:CD36
2394:CD35
2389:CD34
2384:CD33
2367:CD32
2362:CD31
2357:CD30
2352:CD29
2347:CD28
2342:CD27
2337:CD26
2332:CD25
2327:CD24
2322:CD23
2317:CD22
2312:CD21
2307:CD20
2302:CD19
2297:CD18
2280:CD16
2275:CD15
2270:CD14
2265:CD13
2238:CD11
2233:CD10
2130:1–50
2070:1vsc
2055:1vca
2040:1ij9
1974:for
1942:PMID
1899:PMID
1853:PMID
1802:PMID
1767:PMID
1706:PMID
1665:PMID
1492:drug
1463:and
1443:for
1401:and
1326:and
1304:gene
983:7412
413:Bgee
361:Band
322:Chr.
260:Band
219:Chr.
153:OMIM
110:1VSC
106:1VCA
102:1IJ9
83:RCSB
80:PDBe
32:WNCD
2228:CD9
2216:CD8
2211:CD7
2206:CD6
2201:CD5
2196:CD4
2174:CD3
2169:CD2
2142:a-c
2137:CD1
1972:PDB
1932:PMC
1924:doi
1889:doi
1843:PMC
1833:doi
1829:117
1794:doi
1790:151
1757:PMC
1747:doi
1696:doi
1655:PMC
1647:doi
1643:157
1599:doi
1461:EZR
1352:RNA
383:End
282:End
185:OMA
173:838
161:MGI
73:PDB
4677::
4630:,
4610::
4454:,
4450:,
4436:,
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