31:
164:
This information is then used for the logical design of transition-state inhibitors which have the potential to be new biologically active agents. Some of these are in development to be drugs. Schramm's work has translated basic chemical understanding at the quantum mechanical level to a new
483:
476:
469:
752:
492:
228:
737:
727:
322:
150:
762:
204:
as a faculty member. In 1987 he joined the faculty at Albert
Einstein College of Medicine as professor and chair of the biochemistry department.
201:
30:
747:
142:
116:
742:
732:
182:
452:
722:
222:
174:
67:
275:
653:
671:
461:
689:
717:
81:
665:
635:
677:
533:
515:
757:
599:
581:
197:
55:
295:
641:
605:
521:
447:
593:
557:
527:
234:
Harry Eagle Award for
Outstanding Basic Science Teaching from Albert Einstein College of Medicine
178:
146:
345:"Enzymatic transition states, transition-state analogs, dynamics, thermodynamics, and lifetimes"
551:
545:
419:
374:
255:
647:
629:
569:
539:
364:
356:
158:
154:
123:
77:
237:
George A. Sowell Award for
Excellence in Teaching from Temple University School of Medicine
695:
575:
360:
563:
503:
392:
369:
344:
711:
617:
611:
587:
509:
683:
659:
141:(born November 9, 1941) is a professor and Ruth Merns Chair in Biochemistry at the
106:
378:
173:
Schramm earned his bachelor's degree from South Dakota State
College, now
323:"Einstein's Dr. Vern Schramm elected to the National Academy of Sciences"
296:"Einstein's Dr. Vern Schramm elected to the National Academy of Sciences"
231:
from the
Biological Chemistry Division of the American Chemical Society
153:
in 2007. His laboratory's research focuses on the elucidation of
194:
493:
Repligen
Corporation Award in Chemistry of Biological Processes
465:
229:
Repligen
Corporation Award in Chemistry of Biological Processes
753:
Members of the United States
National Academy of Sciences
276:"Vern L Schramm - ComBio 2009, Christchurch, New Zealand"
181:
and his Ph.D. in the mechanism of enzyme action from the
395:. Australian Academy of Science. January–April 2000
122:
112:
102:
87:
73:
63:
40:
21:
177:. He earned his master's degree in nutrition from
212:Schramm was diagnosed with colon cancer in 2022.
193:Schramm secured a postdoctoral position at the
477:
8:
484:
470:
462:
420:"Vern L. Schramm, PhD Biographical Sketch"
256:"Einstein Faculty: Vern L. Schramm, Ph.D."
29:
18:
414:
412:
410:
368:
317:
315:
313:
311:
247:
200:after graduation. Later he joined the
738:Australian National University alumni
361:10.1146/annurev-biochem-061809-100742
7:
728:South Dakota State University alumni
202:Temple University School of Medicine
448:Schramm's profile on Biomed Experts
221:1999 - Rudi Lemberg Award from the
143:Albert Einstein College of Medicine
117:Albert Einstein College of Medicine
91:Rudi Lemberg Award, Repligen Award
14:
763:People from Howard, South Dakota
425:. Ann Arbor, MI. 2009. p. 4
16:American biochemist (born 1941)
183:Australian National University
165:approach to drug development.
1:
349:Annual Review of Biochemistry
223:Australian Academy of Science
175:South Dakota State University
149:. Schramm was elected to the
68:South Dakota State University
151:National Academy of Sciences
325:. Bio-Medicine. May 1, 2007
779:
748:Yeshiva University faculty
743:Temple University faculty
733:Harvard University alumni
499:
132:
95:
28:
690:Wilfred A. van der Donk
216:Awards and distinctions
457:publications on PubMed
82:Kinetic isotope effect
666:David W. Christianson
393:"Rudi Lemberg Fellow"
723:American biochemists
582:Christopher T. Walsh
198:Ames Research Center
155:enzymatic mechanisms
56:Howard, South Dakota
540:Frank H. Westheimer
522:Stephen J. Benkovic
343:Schramm VL (2011).
636:Hung-Wen (Ben) Liu
594:Rowena G. Matthews
576:David S. Eisenberg
558:W. Wallace Cleland
528:Harold A. Scheraga
179:Harvard University
147:Yeshiva University
705:
704:
678:John S. Blanchard
654:Richard Armstrong
564:William P. Jencks
552:Judith P. Klinman
546:Jeremy R. Knowles
534:William W. Parson
136:
135:
97:Scientific career
770:
648:Ronald T. Raines
630:Michael Marletta
570:James A. Spudich
516:Robert H. Abeles
510:Thomas C. Bruice
486:
479:
472:
463:
435:
434:
432:
430:
424:
416:
405:
404:
402:
400:
389:
383:
382:
372:
340:
334:
333:
331:
330:
319:
306:
305:
303:
302:
292:
286:
285:
283:
282:
272:
266:
265:
263:
262:
252:
159:transition state
128:John F. Morrison
124:Doctoral advisor
51:
49:
44:November 9, 1941
33:
19:
778:
777:
773:
772:
771:
769:
768:
767:
708:
707:
706:
701:
696:Michael H. Gelb
624:Vern L. Schramm
600:C. Dale Poulter
495:
490:
444:
439:
438:
428:
426:
422:
418:
417:
408:
398:
396:
391:
390:
386:
342:
341:
337:
328:
326:
321:
320:
309:
300:
298:
294:
293:
289:
280:
278:
274:
273:
269:
260:
258:
254:
253:
249:
244:
218:
210:
191:
171:
139:Vern L. Schramm
78:Enzyme kinetics
64:Alma mater
59:
53:
47:
45:
36:
35:Schramm in 2004
24:
23:Vern L. Schramm
17:
12:
11:
5:
776:
774:
766:
765:
760:
755:
750:
745:
740:
735:
730:
725:
720:
710:
709:
703:
702:
700:
699:
693:
687:
681:
675:
669:
663:
657:
651:
645:
639:
633:
627:
621:
615:
609:
603:
597:
591:
585:
579:
573:
567:
561:
555:
549:
543:
537:
531:
525:
519:
513:
507:
504:Gregorio Weber
500:
497:
496:
491:
489:
488:
481:
474:
466:
460:
459:
450:
443:
442:External links
440:
437:
436:
406:
384:
335:
307:
287:
267:
246:
245:
243:
240:
239:
238:
235:
232:
225:
217:
214:
209:
206:
190:
187:
170:
167:
134:
133:
130:
129:
126:
120:
119:
114:
110:
109:
104:
100:
99:
93:
92:
89:
85:
84:
75:
74:Known for
71:
70:
65:
61:
60:
54:
42:
38:
37:
34:
26:
25:
22:
15:
13:
10:
9:
6:
4:
3:
2:
775:
764:
761:
759:
756:
754:
751:
749:
746:
744:
741:
739:
736:
734:
731:
729:
726:
724:
721:
719:
718:Living people
716:
715:
713:
697:
694:
691:
688:
685:
682:
679:
676:
673:
672:John Lipscomb
670:
667:
664:
661:
658:
655:
652:
649:
646:
643:
642:Frank Raushel
640:
637:
634:
631:
628:
625:
622:
619:
618:David E. Cane
616:
613:
612:JoAnne Stubbe
610:
607:
606:John A. Gerlt
604:
601:
598:
595:
592:
589:
588:Perry A. Frey
586:
583:
580:
577:
574:
571:
568:
565:
562:
559:
556:
553:
550:
547:
544:
541:
538:
535:
532:
529:
526:
523:
520:
517:
514:
511:
508:
505:
502:
501:
498:
494:
487:
482:
480:
475:
473:
468:
467:
464:
458:
456:
451:
449:
446:
445:
441:
421:
415:
413:
411:
407:
394:
388:
385:
380:
376:
371:
366:
362:
358:
354:
350:
346:
339:
336:
324:
318:
316:
314:
312:
308:
297:
291:
288:
277:
271:
268:
257:
251:
248:
241:
236:
233:
230:
226:
224:
220:
219:
215:
213:
208:Personal Life
207:
205:
203:
199:
196:
188:
186:
184:
180:
176:
168:
166:
162:
160:
156:
152:
148:
144:
140:
131:
127:
125:
121:
118:
115:
111:
108:
105:
101:
98:
94:
90:
86:
83:
79:
76:
72:
69:
66:
62:
57:
52:(age 82)
43:
39:
32:
27:
20:
684:Tadhg Begley
660:Carol Fierke
623:
454:
427:. Retrieved
397:. Retrieved
387:
352:
348:
338:
327:. Retrieved
299:. Retrieved
290:
279:. Retrieved
270:
250:
211:
192:
172:
163:
138:
137:
113:Institutions
107:Biochemistry
96:
758:1941 births
161:structure.
712:Categories
429:18 January
399:28 October
355:: 703–32.
329:2010-01-18
301:2010-01-18
281:2010-01-18
261:2010-01-18
259:Retrieved
242:References
48:1941-11-09
169:Education
453:Schramm
379:21675920
370:5502542
227:2006 -
46: (
698:(2018)
692:(2017)
686:(2016)
680:(2015)
674:(2014)
668:(2013)
662:(2012)
656:(2011)
650:(2010)
644:(2009)
638:(2008)
632:(2007)
626:(2006)
620:(2005)
614:(2004)
608:(2003)
602:(2002)
596:(2001)
590:(2000)
584:(1999)
578:(1998)
572:(1997)
566:(1996)
560:(1995)
554:(1994)
548:(1993)
542:(1992)
536:(1991)
530:(1990)
524:(1989)
518:(1988)
512:(1987)
506:(1986)
377:
367:
189:Career
103:Fields
88:Awards
58:, U.S.
455:et al
423:(PDF)
431:2010
401:2010
375:PMID
195:NASA
157:and
41:Born
365:PMC
357:doi
145:of
714::
409:^
373:.
363:.
353:80
351:.
347:.
310:^
185:.
80:,
485:e
478:t
471:v
433:.
403:.
381:.
359::
332:.
304:.
284:.
264:.
50:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.