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Vladimir Hachinski

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145:, and, by extension, helped cement stroke units as the standard of care for stroke patients everywhere. He discovered that the control of the heart by the brain is asymmetric, the fight/flight (sympathetic) response being controlled by the right hemisphere and the rest and digest (parasympathetic) response being controlled by the left hemisphere and damage to one key component (the insula) can lead to heart irregularities and sudden death. This discovery has added fundamental knowledge to how the brain controls the heart and blood pressure and lays the foundation for helping prevent sudden death. 77: 25: 1957:; Nyenhuis, David L.; Black, Sandra E.; Powers, William J.; DeCarli, Charles; Merino, Jose G.; Kalaria, Raj N.; Vinters, Harry V.; Holtzman, David M.; Rosenberg, Gary A.; Wallin, Anders; Dichgans, Martin; Marler, John R.; Leblanc, Gabrielle G. (September 2006). "National Institute of Neurological Disorders and Stroke–Canadian Stroke Network Vascular Cognitive Impairment Harmonization Standards". 661: 360:, stroke, etc.) are treatable as well. He has offered an explanation for the origin of some of these lesions and associated symptoms through his concept of ambibaric brain.  He postulates that the brain has two complementary blood pressure systems, one high and one low and disturbances in each lead to different types of preventable lesions. 524:
on secondary stroke prevention. The study aimed to explore the efficacy of stroke risk-factor counselling and monitoring in effecting lifestyle changes and prescription adherence in patients, as well as exploring barriers and testing possible solutions to effective stroke risk-factor management. The
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At the time, the prevalent view that dementia ensued from the slow strangulation of the brain's blood supply by hardening of the arteries spawned a whole industry of brain vessel “vasodilators”. He showed that brain blood vessels in dementia were not “hardened” and that “vasodilators” were not only
280:, St. Joseph's Hospital, and the London Psychiatric Hospital. He was hired concurrently as a professor at Western University (then called the University of Western Ontario). During this time (and until 1990), he also acted as Director of the Investigative Stroke Unit at London's University Hospital. 481:
He is a participant in an initiative to make brain health the top priority.  He has offered a definition of brain health based on the World Health Organization definition of health” “A state of complete physical, mental and social well-being through a full, balanced, continuous development and
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The MacLachlan Stroke Unit at Sunnybrook, Canada's first stroke unit (est. 1975), was almost 20 years ahead of its time; stroke units have been considered the most effective treatment for stroke patients of all ages, severities, and types only since the 1990s. Hachinski and Norris' early work with
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Hachinski continued to develop and promote his novel approach to dementia — viewing it as a product of preventable and treatable vascular problems, thus itself also amenable to prevention, delay, and mitigation — eventually coining it as the “vascular cognitive impairment approach” to dementias in
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1. The “terrible three” inflict the highest number of death and disability adjusted life years (DALY’s) globally. However, they share the same treatable and preventable risk factors and represent risks for each other. Consequently, conditions that occur together should be prevented together.
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Hachinski, Vladimir; EinhÀupl, Karl; Ganten, Detlev; Alladi, Suvarna; Brayne, Carol; Stephan, Blossom C. M.; Sweeney, Melanie D.; Zlokovic, Berislav; Iturria-Medina, Yasser; Iadecola, Costantino; Nishimura, Nozomi; Schaffer, Chris B.; Whitehead, Shawn N.; Black, Sandra E.; Østergaard, Leif
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describe the rarefaction; and second, they specifically highlighted a previously underappreciated relationship between vascular risk factors for cognitive impairment (i.e., treatable and preventable risk factors for both stroke and multi-infarct dementia) and leukoaraiosis. By coining
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preliminary results were extremely promising, showing that the addition of non-medical personnel to usual stroke care results in far better outcomes and reduced risk-factors. That initial study led to the creation of a multi-centre study in 2009 under the direction of Richard Chan.
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at Sunnybrook Medical Centre, where he and Dr. John W. Norris established the MacLachlan Stroke Unit, Canada's first acute stroke unit. Hachinski remained at Sunnybrook until 1980, when he moved to London, Ontario to act as a neurology consultant for its major health centres:
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Gent, Michael; Donald Easton, J.; Hachinski, VladimirC.; Panak, Edouard; Sicurella, Jane; Blakely, JohnA.; Ellis, DavidJ.; Harbison, JohnW.; Roberts, RobinS.; Turpie, AlexanderG.G. (June 1989). "The Canadian American Ticlopidine Study (Cats) in Thromboembolic Stroke".
452:, he developed (with Robert CotĂ©), the Canadian Neurological Scale – a simple but systematic tool, usable by non-physicians for evaluating and monitoring the neurological status of patients with acute stroke. Later, in 1992, he (with collaborators David Cechetto and 2477:
Gent, M; Blakely, J A; Easton, J D; Ellis, D J; Hachinski, V C; Harbison, J W; Panak, E; Roberts, R S; Sicurella, J; Turpie, A G (October 1988). "The Canadian American Ticlopidine Study (CATS) in thromboembolic stroke. Design, organization, and baseline results".
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expensive but useless. He also developed an eponymic “ischemic score” that continues to be widely used to identify the vascular (treatable and preventable) component of dementia. Successfully distinguishing between the two is tremendously important for patient
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Steingart, A.; Hachinski, V. C.; Lau, C.; Fox, A. J.; Diaz, F.; Cape, R.; Lee, D.; Inzitari, D.; Merskey, H. (1 January 1987). "Cognitive and Neurologic Findings in Subjects With Diffuse White Matter Lucencies on Computed Tomographic Scan (Leuko-Araiosis)".
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2015 led the development of a Proclamation about the joint prevention of stroke and dementia, endorsed by all the major international organizations dealing with both. Since then leading the effort to implement the Proclamation on behalf of the World Stroke
468:, and sudden death following acute stroke. This would eventually lead to the discovery that the insula of the brain is the mediator of these various cardiac complications. Knowing this alters doctors to monitor the heart closely, to prevent sudden death. 383:
as risks for stroke and dementia. Rarefaction of white matter in the brain had already been shown to be correlated with a wide variety of health problems, but these papers were groundbreaking for two reasons especially: First, they introduced the term,
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Hachinski's home province of Ontario, Canada introduced a formal Provincial Stroke System in 2000. Hachinski advocates a strategy of preventing some dementias through the prevention of stroke. With his colleagues, he showed, for the first time, a
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Additionally, he advocates a change in strategy. Instead of using fear, warning people that if they don’t lead a healthy lifestyle they will suffer a stroke, heart disease or dementia decades later, the aim is to achieve brain/mental health now.
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that unit and others helped to cement the importance of dedicated wards for stroke patient monitoring and treatment, but his research over the next 17 years also shaped how those treatments and monitoring methods are executed.
933:, in Spanish under the pen name Alejandro Aranda. In addition, "Dream Waltz," composed by Hachinski and orchestrated by Jason Stanford (Professor of Theory and Composition at Western University), premiered at the 497:
for treatment, Hachinski also has a keen research interest in stroke prevention. He acted as the principal neurological investigator on several seminal, multicentre studies, beginning with the Canadian-American
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He leads a multidisciplinary team studying for the first time together environmental, socioeconomic and individual risk and protective factors in the joint prevention of stroke, heart disease and dementia.
368:, as treating the vascular causes of dementias can mitigate their effects. The scale is a prolifically cited tool, and has since been validated and optimized for use outside of clinical research settings. 401:, rather than solely retroactive and treatment-based approach included other novel coinages, such as “brain at risk,” describing patients without cognitive impairment but with risk factors for it. 404:
Even with these developments, available diagnostic criteria for dementias continued to present a challenge, as they were not able to capture the complex, interactive, and adaptive nature of brain
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2011–2013: Founding chair, World Brain Alliance, a collection of international organizations promoting brain/mental health and reducing brain/mental health disorders, founded on three premises:
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study (1983–88) and the Extracranial/Intracranial Arterial Bypass Surgery trial (1983–87). The former showed a preventative advantage to the drug Ticlopidine over commonly-prescribed
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Hachinski's primary popular medicine contributions have been publications in cooperation with his son, Vladimir, and daughter, Larissa. With Vladimir, he published an article in the
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Hachinski, V. C.; Iliff, L. D.; Zilhka, E.; Du Boulay, G. H.; McAllister, V. L.; Marshall, J.; Russell, R. W. R.; Symon, L. (1 September 1975). "Cerebral Blood Flow in Dementia".
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Since stroke, heart disease and dementia represent risks for each other and share the same risk and protective factors, he advocates preventing this “Triple Threat” together.
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in 2003. Coining and employing the term “brain attack,” the book was written to increase public awareness of the importance of adequate stroke care and early intervention.
133:, the interactions between them and their joint prevention through holistic brain health promotion. He and John W. Norris helped to establish the world's first successful 229: 96: 912:"Transient cerebral ischemia: a historical sketch." In: Historical Aspects of the Neurosciences. (Eds) Rose FC, Bynum WF. Raven Press, New York, pp. 185–193, 1982. 3321: 237: 408:
leading to dementia. For this reason, in 2006, Hachinski decided to lead (with Gabrielle LeBlanc) the development of core common standards to describe the clinical,
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Over the course of his career, Hachinski has been the recipient of many awards and recognitions in his field. The most notable and significant are outlined below.
922: 561:  a. Comprehensive – meaning that all relevant factors need to be considered: Environment, socio-economic factors and individual risk and protective factors 2259:"Special topic section: linkages among cerebrovascular, cardiovascular, and cognitive disorders: Preventing dementia by preventing stroke: The Berlin Manifesto" 3343: 3872: 393:“leukoaraiosis,” Hachinski drew medical practitioners’ attention to these white matter hypodensities in the brains of patients affected by small strokes. 110: 3787: 2698:
Sposato, Luciano A.; Kapral, Moira K.; Fang, Jiming; Gill, Sudeep S.; Hackam, Daniel G.; Cipriano, Lauren E.; Hachinski, Vladimir (1 December 2015).
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has allowed for ongoing improvement of the diagnostic criteria with new knowledge, comparison of results from different studies, and analysis &
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He advocates and will help implement a new approach to the joint prevention of stroke, ischemic heart disease and dementia (the terrible three).
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Oppenheimer, S. M.; Gelb, A.; Girvin, J. P.; Hachinski, V. C. (1 September 1992). "Cardiovascular effects of human insular cortex stimulation".
1105:(the oldest university of the Spanish speaking world) was awarded in 2000. This was followed by Doctor of the University honoris causa from the 4764: 3865: 273: 100: 2557:
EC/IC Bypass Study, Group. (7 November 1985). "Failure of Extracranial–Intracranial Arterial Bypass to Reduce the Risk of Ischemic Stroke".
542:. He is leading a team from 5 Western University faculties, 5 provinces and 4 countries, to find out how and help apply the lessons widely. 712: 555:
2. To be effective prevention has to occur in “actionable units” small enough that their members have or can develop a sense of community.
3541: 3372: 303:’s highest earned degree, Doctor of Science (in Hachinski's case, in medicine), was conferred upon him in 1988 for his “contributions to 2618:"Promoting Adherence to a Regimen of risk factor modification by Trained Non-medical personnel Evaluated against Regular practice Study" 1066: 277: 167: 1729: 41: 4754: 3235: 3185: 3017: 1851: 138: 106: 63: 1110: 729:
An interest in the history of medicine has led Hachinski to publish several articles on the subject over the course of his career:
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Hachinski, VC; Lassen, NA; Marshall, J (27 July 1974). "Multi-infarct dementia. A cause of mental deterioration in the elderly".
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Hachinski, Vladimir (2015). "Stroke and potentially preventable dementias proclamation: updated World Stroke Day proclamation".
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Hachinski, Vladimir; Ganten, Detlev; Lackland, Daniel; Kreutz, Reinhold; Tsioufis, Konstantinos; Hacke, Werner (2018-10-17).
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The scientific bases for preventing stroke and dementia together have been summarized by an international panel of experts.
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Hachinski, Vladimir; Oveisgharan, S; Romney, AK; Shankle, WR (1 February 2012). "Optimizing the Hachinski Ischemic Scale".
4715: 3889: 1060: 988: 618: 337: 159: 114: 3252: 2592: 974: 4784: 4423: 1114: 3033: 772: 484:"Brain health is when thinking, feeling and connecting are the best that they can be in a sage, healthy environment." 1106: 1072: 997:
2016: The McLaughlin Medal of the Royal Society of Canada for “research of sustained excellence in medical science”
122: 328:). Hachinski showed in 1975 that, in fact, only a small minority of dementias were so-caused, and that most were “ 4458: 3351: 2673: 2232: 2043:
Sinha, S.; Warburton, E.A. (September 2000). "The evolution of stroke units—towards a more intensive approach?".
1247: 1048: 926: 637: 178:, and the recipient of several national and international awards and recognitions for his research and advocacy. 3739:"Dr. Vladimir Hachinski's brush with royalty - Schulich School of Medicine & Dentistry - Western University" 3468: 4568: 4521: 4503: 4370: 4365: 535: 379:
in the brains of elderly people. These papers were among the first to recognize the importance of white matter
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Bowler, JV; Hachinski, V (August 1995). "Vascular cognitive impairment: a new approach to vascular dementia".
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Sörös P, Hachinski V (2012). "Cardiovascular and neurological causes of sudden death after ischaemic stroke".
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He possesses an honours degree in history from the University of London, UK, is a Corresponding Member of the
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Hachinski, V (12 September 1992). "Preventable senility: a call for action against the vascular dementias".
1102: 521: 233: 232:(FRCPC) in 1972. From 1973-74, a research fellowship with the Ontario Department of Health brought him to a 163: 45: 2645: 4759: 4669: 4588: 4483: 4109: 3988: 3838: 349: 329: 199: 4583: 3420: 1201:"Department of Clinical Neurological Sciences at Western University - Vladimir Hachinski Faculty Profile" 4013: 3948: 1007: 398: 225: 206: 4296: 3691:"Charitable Trust, Mihara Cerebrovascular Disorder Research Promotion Fund, Mihara Award: Past Winners" 2154:
Oppenheimer, Stephen M.; Cechetto, DF; Hachinski, VC (1 May 1990). "Cerebrogenic Cardiac Arrhythmias".
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At the beginning of Hachinski's career, the view prevailed that most dementias were caused by hardened
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Langhorne, P.; Williams, B.O.; Gilchrist, W.; Howie, K. (August 1993). "Do stroke units save lives?".
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He introduced 9 international editions and a mentorship program for authors from developing countries.
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and senile dementia) and to emphasize that they are preventable and treatable, insofar as their
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Canadian who's who. Volume XXIV, 1989, Simpson, Kieran (ed.); University of Toronto Press, 1988
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Langhorne, Peter; Ramachandra, Samantha; Stroke Unit Trialists' Collaboration (23 April 2020).
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published a series of papers by Hachinski, Harold Merskey and colleagues on the rarefaction of
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2020: Distinguished Inaugural Lecture at the foundation of the African Stroke Organization
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Hachinski, Vladimir; Avan, Abolfazl; Gilliland, Jason; Oveisgharan, Shahram (May 2021).
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Hachinski, Vladimir (1993). "Neurology in Islamic Spain: a call for further research".
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It may require cleanup to comply with Knowledge (XXG)'s content policies, particularly
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Oppenheimer, SM; Hachinski, VC (February 1992). "The cardiac consequences of stroke".
1515: 1391: 1291: 788: 567:  c. Cost-effective – to justify why it should be done ahead of other priorities 4748: 4720: 4710: 4702: 4684: 4679: 4664: 4601: 4534: 4488: 4473: 4453: 4433: 4413: 4380: 4311: 4266: 4253: 4210: 4205: 4139: 4119: 4018: 3993: 3915: 3813:"Honoris Causa para destacado neurĂłlogo canadiense — Universidad Nacional de CĂłrdoba" 3174: 2893: 2835: 2780: 2463: 2406: 2294: 2013: 1880: 1598: 1307: 894: 796: 494: 457: 429: 388:,” a word derived by Hachinski, Paul Potter and Harold Merskey to etymologically and 385: 296: 267:
Following this, he returned to Toronto to take a staff position in the Department of
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Avan, Abolfazl; Hachinski, Vladimir; Brain Health Learn and Act Group (2021-09-27).
2700:"Declining Incidence of Stroke and Dementia: Coincidence or Prevention Opportunity?" 2543: 2351: 2218: 1986: 1939: 1896: 763: 4573: 4516: 4393: 4360: 4352: 4347: 4175: 4147: 4114: 4076: 3910: 3905: 3176:
Stroke: A Comprehensive Guide to "brain Attacks" : Everything You Need to Know
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called, "Music and the Brain" in August 1994. With Larissa, he published the book,
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2022: The Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases
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Hachinski, V. C.; Bowler, J. V.; Loeb, C. (1 October 1993). "Vascular dementia".
1719: 1660: 1581: 1564: 717: 332:” — dementias caused by multiple, small, often imperceptible strokes. The terms “ 228:
in Toronto. He received his formal accreditation in neurology as a Fellow of the
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2004-06: Led working group to develop World Stroke Agenda (2004, Vancouver) and
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2021: The World Federation of Neurology Medal for “Services to World Neurology”
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Hachinski, V. C.; Potter, P.; Merskey, H. (1 January 1987). "Leuko-Araiosis".
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CÎté, R; Hachinski, V C; Shurvell, B L; Norris, J W; Wolfson, C (July 1986).
2056: 1923: 1346: 4233: 4195: 4071: 2238:. Understanding vascular mechanisms > Stroke Related Research > par. 3 2096: 2079: 675: 405: 365: 149: 3396: 3117: 2968: 2870: 2827: 2772: 2725: 2630: 2622:
International Standard Randomised Controlled Trial Number (ISRCTN) Registry
2455: 2398: 2343: 2286: 2064: 1978: 1668: 1590: 1399: 1364: 1299: 860: 755: 506:, while the latter showed that the increasingly popular and very expensive 3314:"Change agents in health care: CMA presents recipients of 2020 CMA Awards" 3158: 2578: 2535: 2499: 2210: 2202: 2175: 2140: 2105: 2021: 1931: 1888: 1828: 1801: 1766: 1704: 1633: 1523: 1323:"Organised inpatient (stroke unit) care for stroke: network meta-analysis" 902: 831: 734:
Hachinski, V (March 1999). "Stalin's last years: delusions or dementia?".
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Hachinski, Vladimir (1994). "Vascular Dementia: A Radical Redefinition".
1278:; Fisher, Marc; Macleod, Malcolm; Davis, Stephen M (May 2008). "Stroke". 671: 433: 417: 353: 304: 218: 191: 187: 130: 3253:"Western News - Partnership captures a beautiful 'Dream' for professors" 3034:"World Stroke Organization - Elections Results - WSO Board of Directors" 2617: 503: 261: 245: 142: 3590:"The Governor General of Canada, Honours, Order of Canada, Recipients" 2811: 2756: 2739:
Hachinski, Vladimir; the Dementia Prevention Initiative (2022-02-01).
2080:"The Canadian Neurological Scale: a preliminary study in acute stroke" 1793: 970:
2020: The American Academy of Neurology Wartenberg Lecture & Award
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2010: Ontario Premier's Discovery Award in life sciences and medicine
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The History of the World Federation of Neurology: The First 50 Years
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Port Perry and Scugog Township Heritage Gallery (scugogheritage.com)
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Hachinski, Vladimir (1986). "H.J.M Barnett: a biographical sketch".
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procedure did not significantly reduce the risk of ischemic stroke.
1565:"The Ambibaric Brain: Pathophysiological and Clinical Implications" 564:  b. Customized – to address the main and manageable problems 448:
In 1986, while he was Director of the Investigative Stroke Unit at
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Fellows of the Royal College of Physicians and Surgeons of Canada
1158:"Vladimir Hachinski, CM, MD, DSc, FRCPC, Doctor honoris causaX4" 1041: 1013:
2013: Chancellor's Award Lecture in Neuroscience and Neurology,
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2021: The 41st T.S. Srinivasan Oration and gold medal and scroll
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Annals of the Royal College of Physicians and Surgeons of Canada
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In 2003, alongside several other researchers, Hachinski began a
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Brain health begins with the mother's and the child's education
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2015: Scientist Career Award, Lawson Health Research Institute
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Hachinski, Vladimir; Iadecola, Costantino; Petersen, Ron C.;
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In addition to his interest in the mechanisms of stroke and
190:, the eldest of three children. He moved with his family to 2796:"Brain health: Key to health, productivity, and well-being" 1077:
2000: Mihara Award in research on cerebrovascular disorders
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and founder of World Brain Alliance. He is a Fellow of the
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Proclamation (2006, Cape Town), observed every October 29.
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This approach is known as the CCCAP or the 3C’s approach.
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the leading publication in the field and president of the
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Hachinski has held many prominent positions in the global
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eanpages - News Blog of the European Academy of Neurology
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2017: Prince Mahidol Award in the field of Public Health,
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Knowledge accrues in pieces but is understood in patterns
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with a focus on design, measurement, and evaluation. The
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Hachinski, Vladimir; Hachinski, Larissa (2003-01-01).
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decrease in the incidence of stroke and dementia at a
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A major contributor to this article appears to have a
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God may forgive our sins, but our bodies hold grudges
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Academia Norteamericana de la Lengua Española (ANLE)
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community, including editor-in-chief of the journal
3421:"Two researchers share the Karolinska Stroke Award" 1563:Hachinski, Vladimir; Østergaard, Leif (June 2021). 283:In 1987, he earned a Master of Science degree from 3173: 1109:(2005), Doctor of Medicine honoris causa from the 941:by the Brno Philharmoniker on September 24, 2013. 230:Royal College of Physicians and Surgeons of Canada 3445:"25 Appointees Named to Ontario's Highest Honour" 2653:Ontario College of Family Physicians (ocfp.on.ca) 2593:"Canadian Stroke Network Annual Report 2002-2003" 3493:"Premier's Discovery Awards (download required)" 1453: 1451: 1449: 1447: 1445: 804:Gasecki, Andrew P.; Hachinski, Vladimir (1996). 340:” would later be widely adopted to describe all 125:. His research pertains in the greatest part to 3715:"Port Perry / Scugog Township Heritage Gallery" 3344:"Announcement of the Prince Mahidol Award 2016" 1537:Alagiakrishnan, Kannayiram; Memon, Mohammed A. 1080:1990: Ontario Trillium Clinical Scientist Award 1003:2014: Fellowship in the Royal Society of Canada 3397:"Search Fellows | The Royal Society of Canada" 3131:Hachinski, K V; Hachinski, V (1 August 1994). 1010:Stroke Award for Excellence in Stroke Research 923:North American Academy of the Spanish Language 610:We need not only rising stars, but North Stars 607:We need fewer watch dogs and more hunting dogs 3873: 718:Stroke: A Comprehensive Guide to Brain Attack 548:The new approach is based on these premises: 8: 1479:"Dr. Vladimir Hachinski, CM, MD, FRCPC, DSc" 624:2006-10: Vice President (North America), WFN 1327:The Cochrane Database of Systematic Reviews 1047:2010: Leadership in Stroke Medicine Award, 1034:2010: Biomedical Science Ambassador Award, 841:Journal of the History of the Neurosciences 713:Journal of the Canadian Medical Association 205:Hachinski received his MD in 1966 from the 3880: 3866: 3858: 1782:Dementia and Geriatric Cognitive Disorders 1483:Canadians for Health Research (chrcrm.org) 1113:(2007), and Doctor honoris causa from the 1059:2006: Distinguished University Professor, 3148: 3107: 3074: 2958: 2715: 2629: 2437: 2325: 2095: 1724:. Elsevier Health Sciences. p. 128. 1580: 1354: 821: 810:Canadian Journal of Neurological Sciences 578:Key administrative positions and advocacy 111:Schulich School of Medicine and Dentistry 64:Learn how and when to remove this message 1846:. Oxford University Press. p. 258. 1844:Cognitive Neurology: A Clinical Textbook 1021:Queen Elizabeth II Diamond Jubilee Medal 929:) and has published a poetry anthology, 75: 1718:Aminoff, Michael Jeffrey (2008-01-01). 1125: 592:There is no health without brain health 424:features of cognitive impairment. This 202:a year later at the top of his class . 182:Early life, education, and early career 4790:Fellows of the Royal Society of Canada 3090:Hachinski, Vladimir (September 2008). 3057:Hachinski, Vladimir (September 2008). 1473: 1471: 1469: 1467: 1465: 1463: 482:exercise of the brain or in lay terms 238:National Hospital for Nervous Diseases 1107:University of Buenos Aires, Argentina 7: 3839:"CASAGIT - Prof. Vladimir Hachinski" 3202:"AcadĂ©micos correspondientes — ANLE" 2168:10.1001/archneur.1990.00530050029008 1918:(10): 2159–60, author reply 2160–1. 1759:10.1001/archneur.1987.00520130013009 1697:10.1001/archneur.1987.00520130024012 1626:10.1001/archneur.1975.00490510088009 1419: 1417: 1222: 1220: 1195: 1193: 1191: 1189: 1187: 1185: 1183: 1181: 1179: 1177: 3324:from the original on 10 August 2020 2894:"Interview with Vladimir Hachinski" 1115:Russian Academy of Medical Sciences 1067:Canadian Academy of Health Sciences 168:Canadian Academy of Health Sciences 117:. He is also a Senior Scientist at 2422:"A new definition of brain health" 2365:Hachinski, Vladimir (2021-08-10). 1971:10.1161/01.STR.0000237236.88823.47 868:"Cajal: crossroads to greatness". 748:10.1111/j.1468-1331.1999.tb00004.x 14: 2646:"Ontario Stroke System Overview" 1111:University of Cordoba, Argentina 925:(a corresponding academy of the 773:"Kos (A poem about Hippocrates)" 659: 291:, studying in the Department of 248:, and then to the Department of 194:as a child. The family moved to 107:Canadian clinical neuroscientist 44:. Please discuss further on the 23: 16:Canadian clinical neuroscientist 4775:Members of the Order of Ontario 3059:"World Stroke Day Proclamation" 2559:New England Journal of Medicine 2314:International Journal of Stroke 2263:International Journal of Stroke 1044:Merit Award in Medical Sciences 636:2008-12 : Vice President, 4770:Members of the Order of Canada 3251:Wallace, Janice (2013-06-20). 3006:Aarli, Johan A. (2014-05-08). 2941:Hachinski, V. (10 June 2013). 1817:BailliĂšre's Clinical Neurology 1721:Neurology and General Medicine 1339:10.1002/14651858.CD000197.pub4 1103:University of Salamanca, Spain 674:format but may read better as 198:thereafter. He graduated from 164:Royal Society of Canada (FRSC) 1: 4765:Ukrainian emigrants to Canada 3890:Canadian Medical Hall of Fame 3230:. Madrid: Editorial Pliegos. 3180:. Firefly Books. p. ix. 2678:London Health Sciences Centre 2528:10.1016/s0140-6736(89)92327-1 2439:10.1016/s1474-4422(21)00102-2 2133:10.1016/S0733-8619(18)30239-1 1516:10.1016/s0140-6736(74)91496-2 1392:10.1016/S1474-4422(11)70291-5 1292:10.1016/S0140-6736(08)60694-7 1055:Member of the Order of Canada 989:Canadian Medical Hall of Fame 789:10.1016/S0140-6736(05)62150-2 736:European Journal of Neurology 619:World Federation of Neurology 450:University Hospital in London 346:primary degenerative dementia 338:vascular cognitive impairment 316:Vascular cognitive impairment 217:and neurology in Toronto and 160:World Federation of Neurology 3318:Canadian Medical Association 3278:"Undreamt dreams can happen" 3276:Hachinski, Vladimir (2016). 3109:10.1161/STROKEAHA.108.531681 3076:10.1161/STROKEAHA.107.000009 2983:"Officers — Past Presidents" 2960:10.1212/WNL.0b013e318296ea48 2863:10.1161/strokeaha.115.011237 2717:10.1001/jamaneurol.2015.2816 2383:10.1212/WNL.0000000000012103 2014:10.1016/0140-6736(93)92813-9 1881:10.1016/0140-6736(92)92177-h 1661:10.1001/archneurol.2011.1698 1582:10.1161/STROKEAHA.120.033492 975:Canadian Medical Association 895:10.1016/0090-3019(86)90334-4 771:Hachinski, Vladimir (1997). 109:and researcher based at the 4729:Marie-Marguerite d'Youville 2571:10.1056/NEJM198511073131904 1073:American Stroke Association 1071:2005: Thomas Willis Award, 651:Non-scientific publications 558:3. The approach has to be: 196:Port Perry, Ontario, Canada 4806: 3348:www.princemahidolaward.org 3226:Aranda, Alejandro (1990). 3012:. OUP Oxford. p. 99. 2800:Alzheimer's & Dementia 2745:Alzheimer's & Dementia 1228:"Order of Canada Citation" 806:"On the names of Babinski" 627:2000-10: Editor-in-Chief, 617:2010-13 : President, 324:(mental deterioration via 123:Robarts Research Institute 4459:Jonathan Campbell Meakins 3896: 3473:www.citizenship.gov.on.ca 2492:10.1161/01.str.19.10.1203 1049:World Stroke Organization 987:2018: Induction into the 973:2020: Awarded one of the 853:10.1080/09647049309525551 823:10.1017/s0317167100039226 638:World Stroke Organization 598:Our brains are our future 397:1994. This proactive and 307:, stroke, and dementia.” 170:(FCAHS), a Member of the 4755:Canadian neuroscientists 4569:Cheryl Rockman-Greenberg 4504:William Thornton Mustard 4371:Charles Philippe Leblond 2327:10.1177/1747493018799965 2271:10.1177/1747493019871915 1924:10.1212/wnl.43.10.2159-a 1255:Dementia Action Alliance 1065:2005: Fellowship in the 326:cerebral atherosclerosis 4067:William Arthur Cochrane 3092:"World Stroke Day 2008" 2097:10.1161/01.str.17.4.731 1015:University of Louisiana 945:Honours and recognition 683:converting this section 522:Canadian Stroke Network 330:multi-infarct dementias 4670:Lucille Teasdale-Corti 4484:Frederick Montizambert 3989:Wilfred Gordon Bigelow 3719:www.scugogheritage.com 2918:"World Brain Alliance" 2631:10.1186/isrctn07607027 2057:10.1093/qjmed/93.9.633 977:'s F.N.G. Starr Award. 540:whole-population level 371:In 1986, the journal, 200:Port Perry High School 186:Hachinski was born in 81: 80:Dr. Vladimir Hachinski 3425:Karolinska Institutet 3377:www.sjhc.london.on.ca 3282:Hektoen International 3133:"Music and the brain" 2203:10.1212/wnl.42.9.1727 2156:Archives of Neurology 1842:Cappa, S. F. (2008). 1747:Archives of Neurology 1685:Archives of Neurology 1649:Archives of Neurology 1614:Archives of Neurology 1097:Hachinski holds four 927:Royal Spanish Academy 373:Archives of Neurology 342:cognitive impairments 207:University of Toronto 79: 42:neutral point of view 4627:F. Estelle R. Simons 4125:Charles George Drake 4052:Harvey Max Chochinov 3522:Partners In Research 3038:www.world-stroke.org 2426:The Lancet Neurology 2233:"A stroke of genius" 1955:Breteler, Monique M. 1248:"A stroke of genius" 1040:2010: International 1036:Partners In Research 301:University of London 209:, and completed his 4584:Jean-Lucien Rouleau 4272:Emmett Matthew Hall 4082:Douglas Harold Copp 3944:Charles Thomas Beer 3934:Henry J. M. Barnett 3888:Inductees into the 3743:www.schulich.uwo.ca 2987:www.wfneurology.org 2922:www.wfneurology.org 2522:(8649): 1215–1220. 2265:: 174749301987191. 1539:"Vascular Dementia" 1286:(9624): 1612–1623. 1138:www.schulich.uwo.ca 1099:honorary doctorates 984:in health sciences. 950:Awards/recognitions 917:Arts and humanities 454:Stephen Oppenheimer 285:McMaster University 274:University Hospital 254:Bispebjerg Hospital 250:Clinical Physiology 192:Caripito, Venezuela 139:Sunnybrook Hospital 4785:People from Scugog 4690:Sir Charles Tupper 4632:Duncan G. Sinclair 4494:Thomas John Murray 4322:Charles B. Huggins 4307:Charles Hollenberg 4287:Donald Olding Hebb 4277:Judith Goslin Hall 4262:Vladimir Hachinski 4186:John G. FitzGerald 3964:Michel G. Bergeron 3695:www.mihara.umin.jp 3320:. 10 August 2020. 2121:Neurologic Clinics 1276:Donnan, Geoffrey A 1257:. researchmedia.eu 1086:Canadian Who’s Who 1083:1989: Featured in 1061:Western University 980:2018: Awarded the 883:Surgical Neurology 725:Medical historical 707:Popular (medicine) 685:, if appropriate. 520:study through the 518:proof of principle 410:neuropsychological 236:laboratory at the 115:Western University 85:Vladimir Hachinski 82: 4742: 4741: 4622:Louis Siminovitch 4282:Michael R. Hayden 4239:Richard Goldbloom 4153:John Robert Evans 4130:Daniel J. Drucker 4004:Adolfo J. de Bold 3929:Frederick Banting 3924:Elizabeth Bagshaw 3566:"WSO 2010 Awards" 3542:"BIAL Award 2010" 2953:(24): 2248–2249. 2857:(11): 3039–3040. 2812:10.1002/alz.12478 2757:10.1002/alz.12586 2565:(19): 1191–1200. 2486:(10): 1203–1210. 2008:(8868): 395–398. 1794:10.1159/000106709 704: 703: 529:Population health 489:Stroke prevention 422:neuropathological 350:Alzheimer disease 334:vascular dementia 289:Hamilton, Ontario 278:Victoria Hospital 215:internal medicine 188:Zhytomyr, Ukraine 172:Orders of Ontario 74: 73: 66: 37:with its subject. 4797: 4695:D. Lorne Tyrrell 4647:Bette Stephenson 4607:Robert B. Salter 4530:Annette O'Connor 4449:Joseph B. Martin 4409:Walter Mackenzie 4399:Ernest McCulloch 4335:David J. Jenkins 4249:Wilfred Grenfell 4181:C. Miller Fisher 4105:Thomas A. Dignan 4024:G. Malcolm Brown 3999:Stephen Blizzard 3984:John Bienenstock 3959:Philip B. Berger 3882: 3875: 3868: 3859: 3853: 3852: 3850: 3849: 3834: 3828: 3827: 3825: 3824: 3809: 3803: 3802: 3800: 3799: 3792:DĂ­as de Historia 3784: 3778: 3777: 3775: 3774: 3759: 3753: 3752: 3750: 3749: 3735: 3729: 3728: 3726: 3725: 3711: 3705: 3704: 3702: 3701: 3687: 3681: 3680: 3678: 3677: 3663: 3657: 3656: 3654: 3653: 3644:. Archived from 3634: 3628: 3627: 3625: 3624: 3618:president.uwo.ca 3610: 3604: 3603: 3601: 3600: 3586: 3580: 3579: 3577: 3576: 3562: 3556: 3555: 3553: 3552: 3538: 3532: 3531: 3529: 3528: 3514: 3508: 3507: 3505: 3504: 3489: 3483: 3482: 3480: 3479: 3465: 3459: 3458: 3456: 3455: 3441: 3435: 3434: 3432: 3431: 3417: 3411: 3410: 3408: 3407: 3393: 3387: 3386: 3384: 3383: 3369: 3363: 3362: 3360: 3359: 3350:. Archived from 3340: 3334: 3333: 3331: 3329: 3310: 3304: 3303: 3301: 3300: 3273: 3267: 3266: 3264: 3263: 3248: 3242: 3241: 3223: 3217: 3216: 3214: 3213: 3198: 3192: 3191: 3179: 3169: 3163: 3162: 3152: 3128: 3122: 3121: 3111: 3102:(9): 2407–2408. 3087: 3081: 3080: 3078: 3069:(9): 2409–2420. 3054: 3048: 3047: 3045: 3044: 3030: 3024: 3023: 3003: 2997: 2996: 2994: 2993: 2979: 2973: 2972: 2962: 2938: 2932: 2931: 2929: 2928: 2914: 2908: 2907: 2905: 2904: 2889: 2883: 2882: 2846: 2840: 2839: 2806:(7): 1396–1407. 2791: 2785: 2784: 2751:(8): 1565–1568. 2736: 2730: 2729: 2719: 2695: 2689: 2688: 2686: 2685: 2670: 2664: 2663: 2661: 2660: 2650: 2642: 2636: 2635: 2633: 2613: 2607: 2606: 2604: 2603: 2597: 2589: 2583: 2582: 2554: 2548: 2547: 2510: 2504: 2503: 2474: 2468: 2467: 2441: 2417: 2411: 2410: 2362: 2356: 2355: 2329: 2305: 2299: 2298: 2253: 2247: 2246: 2244: 2243: 2237: 2229: 2223: 2222: 2186: 2180: 2179: 2151: 2145: 2144: 2116: 2110: 2109: 2099: 2075: 2069: 2068: 2040: 2034: 2033: 1997: 1991: 1990: 1965:(9): 2220–2241. 1950: 1944: 1943: 1907: 1901: 1900: 1864: 1858: 1857: 1839: 1833: 1832: 1812: 1806: 1805: 1788:(3–4): 130–132. 1777: 1771: 1770: 1742: 1736: 1735: 1715: 1709: 1708: 1679: 1673: 1672: 1644: 1638: 1637: 1609: 1603: 1602: 1584: 1575:(6): e259–e262. 1560: 1554: 1553: 1551: 1550: 1534: 1528: 1527: 1510:(7874): 207–10. 1499: 1493: 1492: 1490: 1489: 1475: 1458: 1455: 1440: 1439: 1437: 1436: 1421: 1412: 1411: 1375: 1369: 1368: 1358: 1318: 1312: 1311: 1272: 1266: 1265: 1263: 1262: 1252: 1244: 1238: 1237: 1235: 1234: 1224: 1215: 1214: 1212: 1211: 1197: 1172: 1171: 1169: 1168: 1154: 1148: 1147: 1145: 1144: 1130: 1093:Honorary degrees 1027:Order of Ontario 906: 877: 876:: 290–292. 1992. 864: 835: 825: 800: 767: 699: 696: 690: 681:You can help by 663: 662: 655: 644:World Stroke Day 221:, followed by a 104: 69: 62: 58: 55: 49: 35:close connection 27: 26: 19: 4805: 4804: 4800: 4799: 4798: 4796: 4795: 4794: 4745: 4744: 4743: 4738: 4642:Nahum Sonenberg 4612:Charles Scriver 4579:Noralou P. 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Carty 3954:Bernard Belleau 3892: 3886: 3856: 3847: 3845: 3836: 3835: 3831: 3822: 3820: 3811: 3810: 3806: 3797: 3795: 3786: 3785: 3781: 3772: 3770: 3761: 3760: 3756: 3747: 3745: 3737: 3736: 3732: 3723: 3721: 3713: 3712: 3708: 3699: 3697: 3689: 3688: 3684: 3675: 3673: 3665: 3664: 3660: 3651: 3649: 3636: 3635: 3631: 3622: 3620: 3612: 3611: 3607: 3598: 3596: 3588: 3587: 3583: 3574: 3572: 3564: 3563: 3559: 3550: 3548: 3540: 3539: 3535: 3526: 3524: 3516: 3515: 3511: 3502: 3500: 3491: 3490: 3486: 3477: 3475: 3467: 3466: 3462: 3453: 3451: 3449:news.ontario.ca 3443: 3442: 3438: 3429: 3427: 3419: 3418: 3414: 3405: 3403: 3395: 3394: 3390: 3381: 3379: 3371: 3370: 3366: 3357: 3355: 3342: 3341: 3337: 3327: 3325: 3312: 3311: 3307: 3298: 3296: 3275: 3274: 3270: 3261: 3259: 3250: 3249: 3245: 3238: 3225: 3224: 3220: 3211: 3209: 3200: 3199: 3195: 3188: 3171: 3170: 3166: 3130: 3129: 3125: 3089: 3088: 3084: 3056: 3055: 3051: 3042: 3040: 3032: 3031: 3027: 3020: 3005: 3004: 3000: 2991: 2989: 2981: 2980: 2976: 2940: 2939: 2935: 2926: 2924: 2916: 2915: 2911: 2902: 2900: 2891: 2890: 2886: 2848: 2847: 2843: 2793: 2792: 2788: 2738: 2737: 2733: 2710:(12): 1529–31. 2697: 2696: 2692: 2683: 2681: 2672: 2671: 2667: 2658: 2656: 2648: 2644: 2643: 2639: 2616:Chan, Richard. 2615: 2614: 2610: 2601: 2599: 2595: 2591: 2590: 2586: 2556: 2555: 2551: 2512: 2511: 2507: 2476: 2475: 2471: 2419: 2418: 2414: 2364: 2363: 2359: 2307: 2306: 2302: 2255: 2254: 2250: 2241: 2239: 2235: 2231: 2230: 2226: 2188: 2187: 2183: 2153: 2152: 2148: 2118: 2117: 2113: 2077: 2076: 2072: 2042: 2041: 2037: 1999: 1998: 1994: 1952: 1951: 1947: 1909: 1908: 1904: 1875:(8820): 645–8. 1866: 1865: 1861: 1854: 1841: 1840: 1836: 1814: 1813: 1809: 1779: 1778: 1774: 1744: 1743: 1739: 1732: 1717: 1716: 1712: 1681: 1680: 1676: 1646: 1645: 1641: 1611: 1610: 1606: 1562: 1561: 1557: 1548: 1546: 1536: 1535: 1531: 1501: 1500: 1496: 1487: 1485: 1477: 1476: 1461: 1456: 1443: 1434: 1432: 1424:Arculus, Paul. 1423: 1422: 1415: 1377: 1376: 1372: 1333:(4): CD000197. 1320: 1319: 1315: 1274: 1273: 1269: 1260: 1258: 1250: 1246: 1245: 1241: 1232: 1230: 1226: 1225: 1218: 1209: 1207: 1199: 1198: 1175: 1166: 1164: 1156: 1155: 1151: 1142: 1140: 1132: 1131: 1127: 1123: 1095: 952: 947: 939:Vienna, Austria 919: 880: 867: 838: 803: 770: 733: 727: 709: 700: 694: 691: 680: 664: 660: 653: 580: 531: 511:arterial bypass 491: 462:cardiac enzymes 442: 426:standardization 390:Hippocratically 358:atherosclerosis 318: 313: 234:cerebrovascular 223:neurophysiology 184: 87: 70: 59: 53: 50: 39: 28: 24: 17: 12: 11: 5: 4803: 4801: 4793: 4792: 4787: 4782: 4777: 4772: 4767: 4762: 4757: 4747: 4746: 4740: 4739: 4737: 4736: 4731: 4726: 4718: 4713: 4708: 4700: 4692: 4687: 4682: 4677: 4672: 4667: 4662: 4654: 4652:Calvin Stiller 4649: 4644: 4639: 4634: 4629: 4624: 4619: 4614: 4609: 4604: 4599: 4591: 4586: 4581: 4576: 4571: 4566: 4558: 4550: 4545: 4543:Anthony Pawson 4540: 4532: 4527: 4519: 4514: 4512:Arnold Naimark 4509: 4501: 4499:Fraser Mustard 4496: 4491: 4486: 4481: 4479:Julio Montaner 4476: 4471: 4469:Ronald Melzack 4466: 4461: 4456: 4451: 4446: 4441: 4436: 4431: 4426: 4421: 4416: 4411: 4406: 4404:John McEachern 4401: 4396: 4391: 4386:Peter Lougheed 4383: 4378: 4373: 4368: 4366:Bernard Langer 4363: 4358: 4350: 4345: 4337: 4332: 4330:Herbert Jasper 4327: 4319: 4314: 4309: 4304: 4299: 4294: 4289: 4284: 4279: 4274: 4269: 4264: 4259: 4251: 4246: 4241: 4236: 4231: 4226: 4224:Jacques Genest 4221: 4219:William Gallie 4216: 4208: 4203: 4198: 4193: 4191:Claude Fortier 4188: 4183: 4178: 4173: 4168: 4166:Sylvia Fedoruk 4163: 4158: 4150: 4145: 4137: 4135:Jacalyn Duffin 4132: 4127: 4122: 4117: 4112: 4107: 4102: 4097: 4092: 4084: 4079: 4074: 4069: 4064: 4059: 4054: 4049: 4047:Brock Chisholm 4044: 4039: 4034:Alan C. 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Hogg 4310: 4308: 4305: 4303: 4300: 4298: 4295: 4293: 4292:Carol Herbert 4290: 4288: 4285: 4283: 4280: 4278: 4275: 4273: 4270: 4268: 4267:Antoine Hakim 4265: 4263: 4260: 4258: 4255: 4254:Gordon Guyatt 4252: 4250: 4247: 4245: 4242: 4240: 4237: 4235: 4232: 4230: 4227: 4225: 4222: 4220: 4217: 4215: 4212: 4211:Henry Friesen 4209: 4207: 4206:Clarke Fraser 4204: 4202: 4199: 4197: 4194: 4192: 4189: 4187: 4184: 4182: 4179: 4177: 4174: 4172: 4169: 4167: 4164: 4162: 4159: 4157: 4154: 4151: 4149: 4146: 4144: 4141: 4140:Jean Dussault 4138: 4136: 4133: 4131: 4128: 4126: 4123: 4121: 4120:Tommy Douglas 4118: 4116: 4113: 4111: 4108: 4106: 4103: 4101: 4098: 4096: 4093: 4091: 4088: 4085: 4083: 4080: 4078: 4075: 4073: 4070: 4068: 4065: 4063: 4060: 4058: 4055: 4053: 4050: 4048: 4045: 4043: 4040: 4038: 4035: 4032: 4030: 4027: 4025: 4022: 4020: 4019:Henri Breault 4017: 4015: 4012: 4010: 4007: 4005: 4002: 4000: 3997: 3995: 3994:Michael Bliss 3992: 3990: 3987: 3985: 3982: 3980: 3977: 3975: 3972: 3970: 3967: 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Index

close connection
neutral point of view
talk page
Learn how and when to remove this message
Dr. Vladimir Hachinski
CM
OOnt
FRCPC
FRSC
Canadian clinical neuroscientist
Schulich School of Medicine and Dentistry
Western University
London
Robarts Research Institute
stroke
dementia
stroke unit
Sunnybrook Hospital
Toronto
neurology
Stroke
World Federation of Neurology
Royal Society of Canada (FRSC)
Canadian Academy of Health Sciences
Orders of Ontario
Canada
Zhytomyr, Ukraine
Caripito, Venezuela
Port Perry, Ontario, Canada
Port Perry High School

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