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Walter Dobrogosz

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at N. C. State in 1968 and remained there until his retirement in 2003. While at N. C. State, he taught the graduate courses 'Metabolic Regulatory Mechanisms,' 'Microbial Physiology and Bioenergetics,' and 'Metabolism, Growth, and Regulation,' and the undergraduate courses "General Microbiology,'
639:, at which he also became very competitive. One of the premier handball players in North Carolina during the 1970s, Dobrogosz won many tournaments, including the 1975 and 1977 North Carolina amateur men's singles championships, and the 1972, 1974, 1980, and 1981 Raleigh 326: 578:(ASM) throughout his career. He has served on the editorial board of the ASM journal, chaired the Genetics and Physiology section of the ASM, and presided for two terms over the ASM's North Carolina branch. 581:
Since retirement, Dobrogosz has remained an active advocate of the "probiotic concept"; the importance of microbes in human health. He continues to publish review articles on
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infections, and mediate the body's immune response. PBI was purchased by public investors in 1990, and later its name was changed to BioGaia AB. It continues to market
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had the potential to be a protective probiotic. Dobrogosz and his fellows obtained patents on both the bacterium and reuterin, and later began to market
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produces a potent anti-microbial substance, which they termed "reuterin." Based on this, they hypothesized that the human-specific strain of
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You can help by adding reliable sources to this article. Contentious material about living people that is unsourced or poorly sourced
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Dobrogosz founded Probiologics International (PBI) in 1987, a company devoted to the commercial prospects of
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Professor Dobrogosz married his wife Donna in 1953 and is the father of four children, including musician
492: 405: 498: 465: 436: 41: 972: 847:"Effects of aerobic and anaerobic shock on catabolite repression in cyclic AMP suppressor mutants of 517: 449: 585:, in addition to attending and lecturing at conferences on probiotic and microbiological research. 547:, and found that L. reuteri is effective in preventing diarheal diseases and other gut infections. 453: 512:
The focus of Dobrogosz's research shifted in 1985, when he and student Lars Axelsson identified
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Casas, Ivan A.; Dobrogosz, Walter J. (December 1, 2000). "Validation of the Probiotic Concept:
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Dobrogosz has been an avid athlete since his youth. In high school, he lettered in
473: 461: 457: 866: 718:"Antagonistic activities of lactic acid bacteria in food and feed fermentations" 624: 506: 502: 481: 468:. In 1960โ€“62, Dobrogosz held an NIH-supported postdoctoral fellowship at the 897: 669: 560: 432: 429: 819: 884: 837: 790: 743: 708: 699: 656:
Confers Broad-spectrum Protection against Disease in Humans and Animals".
772: 679:"Principles of ex ovo competitive exclusion and in ovo administration of 800:"Production and isolation of reuterin, a growth inhibitor produced by 325: 753:"Chemical characterization of an antimicrobial substance produced by 606: 568: 556: 521: 349: 148:. Statements consisting only of original research should be removed. 640: 798:
Talarico TL, Casas IA, Chung TC, Dobrogosz WJ (December 1988).
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Edens FW, Parkhurst CR, Casas IA, Dobrogosz WJ (January 1997).
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from the article and its talk page, especially if potentially
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In particular, his research focused on the phenomenon of
524:, Dobrogosz and colleague Sven Lindgren discovered that 456:, and received his B.S., Masters, and Ph.D. degrees in 137: 401: 393: 375: 367: 357: 332: 316: 501:, a regulatory system involving interactions of 480:Early in his research career, Dobrogosz studied 536:for its benefits to human and animal health. 8: 716:Lindgren SE, Dobrogosz WJ (September 1990). 448:Dobrogosz was born on September 3, 1933, in 616:, and grandfather of nine. He now lives in 50:Learn how and when to remove these messages 470:University of Illinois at Urbana-Champaign 324: 313: 213:about living persons that is unsourced or 898:http://microbiology.ncsu.edu/WJD/WJD.html 874: 827: 780: 733: 698: 509:and other inducible systems in bacteria. 302:Learn how and when to remove this message 284:Learn how and when to remove this message 164:Learn how and when to remove this message 102:Learn how and when to remove this message 914: 658:Microbial Ecology in Health and Disease 968:North Carolina State University people 751:Talarico TL, Dobrogosz WJ (May 1989). 609:control), and his mother was Slovac. 574:Dobrogosz has been involved with the 7: 571:or milk-based products, worldwide. 735:10.1111/j.1574-6968.1990.tb04885.x 14: 845:Lee JH, Dobrogosz WJ (May 1983). 601:ancestry. His father was born in 576:American Society for Microbiology 31:This article has multiple issues. 963:Eberly College of Science alumni 953:21st-century American biologists 180: 118: 61: 20: 543:. PBI began to carry out human 426:North Carolina State University 410:North Carolina State University 39:or discuss these issues on the 484:regulation in such species as 1: 867:10.1128/jb.154.2.992-994.1983 362:Pennsylvania State University 808:Antimicrob. Agents Chemother 761:Antimicrob. Agents Chemother 191:biography of a living person 72:biography of a living person 424:is a professor emeritus of 218:must be removed immediately 144:the claims made and adding 84:must be removed immediately 994: 923:"Dobrogosz, Walter Jerome" 397:Bacteriology, biochemistry 551:is now known to maintain 415: 386: 323: 958:American microbiologists 670:10.3402/mehd.v12i4.8196 618:Raleigh, North Carolina 903:http://www.biogaia.se/ 820:10.1128/aac.32.12.1854 493:Salmonella typhimurium 406:University of Illinois 205:Please help by adding 802:Lactobacillus reuteri 755:Lactobacillus reuteri 681:Lactobacillus reuteri 654:Lactobacillus reuteri 647:Selected publications 567:, often contained in 518:lactic acid bacterium 499:catabolite repression 466:Penn State University 437:Lactobacillus reuteri 408:at Urbana-Champaign, 773:10.1128/aac.33.5.674 450:Albion, Pennsylvania 211:Contentious material 722:FEMS Microbiol. Rev 700:10.1093/ps/76.1.179 593:Though born in the 352:, Pennsylvania, USA 597:, Dobrogosz is of 454:Erie, Pennsylvania 233:"Walter Dobrogosz" 129:possibly contains 629:American football 559:, bacterial, and 444:Professional life 419: 418: 388:Scientific career 343:September 3, 1933 312: 311: 304: 294: 293: 286: 268: 194:needs additional 174: 173: 166: 131:original research 112: 111: 104: 54: 985: 937: 936: 934: 933: 919: 888: 878: 849:Escherichia coli 841: 831: 794: 784: 747: 737: 712: 702: 673: 643:doubles titles. 599:Eastern European 555:health, prevent 487:Escherichia coli 452:. He grew up in 422:Walter Dobrogosz 379:Four, including 346: 342: 340: 328: 318:Walter Dobrogosz 314: 307: 300: 289: 282: 278: 275: 269: 267: 226: 207:reliable sources 184: 183: 176: 169: 162: 158: 155: 149: 146:inline citations 122: 121: 114: 107: 100: 96: 93: 87: 65: 64: 57: 46: 24: 23: 16: 993: 992: 988: 987: 986: 984: 983: 982: 943: 942: 941: 940: 931: 929: 921: 920: 916: 911: 894: 844: 797: 750: 728:(1โ€“2): 149โ€“63. 715: 676: 651: 649: 633:track and field 614:Steve Dobrogosz 591: 545:clinical trials 446: 381:Steve Dobrogosz 353: 347: 344: 338: 336: 319: 308: 297: 296: 295: 290: 279: 273: 270: 227: 225: 204: 185: 181: 170: 159: 153: 150: 135: 123: 119: 108: 97: 91: 88: 81: 66: 62: 25: 21: 12: 11: 5: 991: 989: 981: 980: 975: 970: 965: 960: 955: 945: 944: 939: 938: 913: 912: 910: 907: 906: 905: 900: 893: 890: 814:(12): 1854โ€“8. 648: 645: 603:Warsaw, Poland 590: 587: 445: 442: 417: 416: 413: 412: 403: 399: 398: 395: 391: 390: 384: 383: 377: 373: 372: 369: 365: 364: 359: 355: 354: 348: 334: 330: 329: 321: 320: 317: 310: 309: 292: 291: 215:poorly sourced 188: 186: 179: 172: 171: 126: 124: 117: 110: 109: 69: 67: 60: 55: 29: 28: 26: 19: 13: 10: 9: 6: 4: 3: 2: 990: 979: 978:Living people 976: 974: 971: 969: 966: 964: 961: 959: 956: 954: 951: 950: 948: 928: 927:www.poles.org 924: 918: 915: 908: 904: 901: 899: 896: 895: 891: 889: 886: 882: 877: 872: 868: 864: 860: 856: 852: 850: 842: 839: 835: 830: 825: 821: 817: 813: 809: 805: 803: 795: 792: 788: 783: 778: 774: 770: 766: 762: 758: 756: 748: 745: 741: 736: 731: 727: 723: 719: 713: 710: 706: 701: 696: 693:(1): 179โ€“96. 692: 688: 684: 682: 674: 671: 667: 663: 659: 655: 646: 644: 642: 638: 634: 630: 626: 621: 619: 615: 610: 608: 604: 600: 596: 595:United States 589:Personal life 588: 586: 584: 579: 577: 572: 570: 566: 562: 558: 554: 550: 546: 542: 537: 535: 531: 527: 523: 519: 515: 510: 508: 504: 500: 496: 494: 489: 488: 483: 478: 475: 471: 467: 463: 459: 455: 451: 443: 441: 439: 438: 434: 431: 427: 423: 414: 411: 407: 404: 400: 396: 392: 389: 385: 382: 378: 374: 370: 366: 363: 360: 356: 351: 345:(age 91) 335: 331: 327: 322: 315: 306: 303: 288: 285: 277: 266: 263: 259: 256: 252: 249: 245: 242: 238: 235: โ€“  234: 230: 229:Find sources: 223: 219: 216: 212: 208: 202: 201: 197: 192: 187: 178: 177: 168: 165: 157: 147: 143: 139: 133: 132: 127:This article 125: 116: 115: 106: 103: 95: 85: 79: 78: 77:single source 73: 68: 59: 58: 53: 51: 44: 43: 38: 37: 32: 27: 18: 17: 930:. Retrieved 926: 917: 861:(2): 992โ€“4. 858: 855:J. Bacteriol 854: 848: 843: 811: 807: 801: 796: 767:(5): 674โ€“9. 764: 760: 754: 749: 725: 721: 714: 690: 686: 680: 675: 661: 657: 653: 650: 622: 611: 605:(then under 592: 582: 580: 573: 564: 548: 540: 538: 533: 529: 525: 513: 511: 491: 485: 479: 474:Microbiology 462:biochemistry 458:bacteriology 447: 435: 421: 420: 402:Institutions 387: 298: 280: 271: 261: 254: 247: 240: 228: 217: 200:verification 193: 160: 151: 128: 98: 89: 83: 75:relies on a 74: 47: 40: 34: 33:Please help 30: 973:1933 births 947:Categories 932:2018-01-10 909:References 687:Poult. Sci 625:basketball 583:L. reuteri 565:L. reuteri 553:intestinal 549:L. reuteri 541:L. reuteri 534:L. reuteri 530:L. reuteri 526:L. reuteri 514:L. reuteri 507:lac operon 503:cyclic AMP 339:1933-09-03 274:April 2018 244:newspapers 154:April 2018 138:improve it 92:April 2018 36:improve it 561:protozoal 482:metabolic 433:bacterium 430:probiotic 358:Education 196:citations 142:verifying 42:talk page 637:handball 516:, a new 376:Children 222:libelous 892:Sources 885:6302089 838:3245697 791:2751282 744:2125429 709:9037704 607:Russian 258:scholar 136:Please 883:  876:217556 873:  836:  829:176032 826:  789:  782:172512 779:  742:  707:  631:, and 569:yogurt 557:fungal 522:Sweden 394:Fields 368:Spouse 350:Albion 260:  253:  246:  239:  231:  664:(4). 464:from 371:Donna 265:JSTOR 251:books 189:This 70:This 881:PMID 834:PMID 787:PMID 740:PMID 705:PMID 641:YMCA 490:and 460:and 333:Born 237:news 198:for 871:PMC 863:doi 859:154 824:PMC 816:doi 777:PMC 769:doi 730:doi 695:doi 666:doi 140:by 949:: 925:. 879:. 869:. 857:. 853:. 832:. 822:. 812:32 810:. 806:. 785:. 775:. 765:33 763:. 759:. 738:. 724:. 720:. 703:. 691:76 689:. 685:. 662:12 660:. 627:, 620:. 440:. 341:) 209:. 45:. 935:. 887:. 865:: 851:" 840:. 818:: 804:" 793:. 771:: 757:" 746:. 732:: 726:7 711:. 697:: 683:" 672:. 668:: 495:. 337:( 305:) 299:( 287:) 281:( 276:) 272:( 262:ยท 255:ยท 248:ยท 241:ยท 224:. 203:. 167:) 161:( 156:) 152:( 134:. 105:) 99:( 94:) 90:( 86:. 80:. 52:) 48:(

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Albion
Pennsylvania State University
Steve Dobrogosz

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