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final years of high school (10th-13th grade), but often come from middle or even elementary schools. The High School Lab has very stable numbers of visitors (about 2,000 annually). It offers day-long practical laboratory courses with diverse experimental tasks. It also hosts a week-long summer academy for ca. 20 students every year, in the course of which participants work on projects, visit local research institutes and listen to scientific talks. Further training for teachers is also on offer, which annually draw a crowd of up to 200 participants. The High School Lab has been headed by Prof Uwe Ilg since its inception.
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expanded to three graduate schools concurrently with the CIN's foundation. The resulting GTC ensures a common structural basis and coordination of studies in neuroscience at the
University of Tübingen. The added two graduate schools are the school of Cellular and Molecular Neuroscience and the school of Neural Information Processing. These schools differ from the behaviour- and systems-oriented first graduate school by focusing on the cell and molecular level and on theoretical neuroscience, respectively.
504:; and the HIH and DZNE, with whom the CIN forms the neurocampus Schnarrenberg enabling efficient sharing of resources and facilities as well as constant scientific discourse. Common colloquia, many informal meetings, and an annual get-together are intended to foster that discourse further. The close cooperation among these institutions is evidenced by several joint research groups in sensomotoric research and
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564:. After four years, junior research group leaders undergo competitive evaluation based on numerous indicators of scientific accomplishment (publication record, third-party funding won etc.). External reviews mark the success level of the evaluation and are the factor determining whether the candidate receives tenure in the form of a professorship.
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scientific advisory board visits Tübingen at least annually to receive a report on scientific and structural developments at the CIN, to evaluate the work and role of junior research group leaders, and to advise. The board then deliberates on the developments of the past year and prepare a report to the president of the university.
579:, have supported the High School Lab for Neuroscience. 2014, a friends’ association was founded. The High School Lab has repeatedly garnered attention in the local media. 2010 it was commended as a “Ausgewählter Ort” (chosen location) in the framework of the initiative “Deutschland – Land der Ideen” (“Germany – Land of Ideas”).
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were joined by another 23 founding members. The CIN is intended as a common platform for exchange, coordination and cooperation within the Tübingen neuroscience community. It has dynamically developed its membership, which now encompasses about 90 Tübingen-based neuroscientists chosen based on scientific criteria.
567:
When the CIN was founded, the High School Lab in
Neuroscience was also established. The High School Lab is a place for learning outside school, but aimed at high school students to interest them in work as a researcher and neuroscientific research questions. Students addressed are most often in their
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Institute for
Manufacturing Engineering and Automation (Fraunhofer IPA). In 2010, many CIN members took part in the successful application for the establishment of the Tübingen Bernstein Center for Computational Neuroscience (BCCN), which was coordinated by CIN professor Matthias Bethge and supported
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The CIN was applied for as a cluster of excellence starting during the second part of the
Excellence Initiative's first round (application: 2006/2007; projects commencing 1 November 2007). It was officially inaugurated on 8 December 2008. At the cluster's foundation, 25 principal investigators (PIs)
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The CIN's statutes require an external scientific advisory board to oversee and advise work at the CIN. Board members are internationally renowned researchers whose area of interest lies in one or more CIN research areas. Board members are called by the president of the
University of Tübingen. The
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When the
Excellence Initiative entered its second round (application: 2010/2011; projects commencing 1 November 2012), the CIN applied for and received a five-year extension of funding and support. In that year, the University of Tübingen also successfully applied for Excellence Initiative support
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Ever since it moved in in early 2012 (official opening ceremony: 14 May 2012), the CIN has been at home in a building of its own on the Tübingen
University Hospital's Schnarrenberg campus. It is situated next to institutions that are neighbours topologically as well as scientifically, nestled in
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students are handled by the international
Graduate Training Centre of Neuroscience (GTC). The GTC encompasses three graduate schools with different focus fields. Built upon the International Max Planck Research School (IMPRS) of Neural and Behavioural Sciences founded in 1999, the institute was
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Research at the CIN is roughly divided into five research areas. Three research areas are defined by the shared level of observation of research groups engaged in them: the cellular level („The sensory and neuronal basis of integrative brain function (Cellular Level)“), the network level („The
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Laboratory rotations ensure GTC students are introduced to self-organised scientific project work early on. Students at the GTC have many options to take responsibility; for instance, they can invite guest speakers, and they organise an annual conference aimed at junior neuroscientists
352:(MEG) are very important. Measurements taken with these methods boast very high temporal resolution, but comparatively low spatial resolution. Fortunately, it is possible to establish anatomical reference points for these electrophysiological methods when they are combined with
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All three graduate schools teach in
English. More than 50% of their students come from abroad. Candidates are chosen based on a multi-stage selection procedure. Currently, ca. 85 students aim for a Master of Science degree, while ca. 250 aim to become Doctors of Science.
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Researchers at the CIN seek to answer these questions using an integrative approach encompassing multiple levels of observation. These levels range from the lowest level of the genetic, cellular and molecular basis of brain functions through intermediate levels of larger
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To these three are added two research areas of a more overarching character which emphasise the development of methods and translation into applications. The research area “Designing the tools to probe integrative brain functions (Advanced Tools)“ focuses on
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The CIN is an interfaculty institution connecting three faculties of the
University of Tübingen: the Faculty of Science, the Faculty of Medicine, and the Faculty of Humanities. The CIN is involved in close cooperation with several local partners: the
356:(fMRI), as fMRI reaches spatial resolutions about two orders of magnitude greater. To further improve spatial resolution of MRI, research groups at the CIN investigate the potential of high field technology, e.g. an experimental 9.4
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sensory and neuronal basis of integrative brain function (Network Level)“) and the cognitive-behavioural level („Cognition and behaviour originating from integrative brain functions (Cognitive Level)“. All of these areas employ
38:
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Classical methods such as analysing brain lesions are in use in order to understand the role of certain neural circuits. Furthermore, the CIN makes use of a large number of experimental methods such as non-invasive
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in 2007/2008. About 90 scientists with their research groups – 21 of which are supported with excellence initiative funds – form the CIN's membership. The focus of their work is on basic research in systems
266:(DZNE) on the other. Before it moved into its current building, the CIN was installed in a building of the Tübingen-Reutlingen Technology Park, in close proximity to the Tübingen Max Planck campus.
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Due to their multiple levels of observation, the CIN's researchers employ a wide range of methods. Where investigation into the human brain is concerned, non-invasive imaging techniques such as
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Besides these electrophysiological methods, which are constantly undergoing refinement, numerous optical methods are employed at the CIN to make individual cells or cell clusters visible
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Research at the CIN focuses on the twofold question how the brain generates its functions (such as perception, memory, emotion, communication, motor skills), and how diseases (such as
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These different levels of observation require different scientific methods, resulting in different manners in which research results can be translated into medicine and engineering.
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273:, who is also director of the Department of Cognitive Neurology at the Center for Neurology/Hertie Institute for Clinical Brain Research at Tübingen University Hospital.
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techniques, while the research area “Brain-related technical applications and neuroprosthetics (Neurotechnology)“ aims to promote innovative rehabilitation methods and
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The CIN further engages in close collaboration with the Natural and Medical Sciences Institute at the University of Tübingen (NMI), with the Tübingen branch of the
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461:(TMS), or invasive electrical micro stimulation or local pharmacological manipulation. These methods are more and more complemented by invasive
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and integrative approach, it encompasses projects rooted in biology, medicine, physics, computer science and engineering, as well as
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911:"www.bccn-tuebingen.de/about-bccn/press/release/foundation-of-bernstein-center-for-computational-neuroscience-tuebingen-29.html"
433:. The most recent innovation in optical methods is the localisation of protein molecules in neuronal compartments by combining
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phase, and to responsibly direct all of its activities. Junior research group leaders are supported and mentored by the CIN's
500:, with whom the CIN has established a joint professorship and research group in high field magnetic resonance tomography; the
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472:, theoretical neuroscience approaches to simulate neuronal networks and generate hypotheses testable in further experiments.
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of conventional light microscopy. This combined method is used by a CIN junior research group to analyse the consequences of
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MRI scanner for scanning the brains of human test subjects, and a 14.1 Tesla scanner for small animals, both in use at the
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The CIN supports young people going into research at multiple levels of their career. Education and training of
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Higher spatio-temporal resolutions are currently only available in invasive experiments, which usually require
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642:"Pressemitteilung des Ministeriums für Wissenschaft, Forschung und Kunst Baden-Württemberg, 8. August 2008"
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Joachim Müller-Jung, „Ein Netzwerk, mit System erforscht”, Frankfurter Allgemeine Zeitung, 31. Mai 2017.
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enabling information processing all the way up to high-level observation of the principles governing
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technique, which enables measurements of membrane potentials in different parts of a given
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Since its inception, the CIN has been headed by its spokesman, the neurobiologist Prof Dr
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pioneered research into the fundamental principles of vision and information processing.
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It may require cleanup to comply with Knowledge (XXG)'s content policies, particularly
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693:"www.gesundheitsindustrie-bw.de/de/fachbeitrag/pm/neubau-fuer-exzellenzcluster-cin/"
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damage incurred in the course of inflammatory or neurodegenerative diseases such as
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in Germany. It was installed as a cluster of excellence within the framework of the
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concept. This allows promising junior researchers to head a research group after a
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897:"www.cin.uni-tuebingen.de/about-cin/our-partners/regional-national-partners.html"
956:"www.cin.uni-tuebingen.de/about-cin/background/the-cin-in-a-nutshell.html#c1573"
839:"www.gesundheitsindustrie-bw.de/en/article/news/distant-goal-retina-generation/"
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368:. For non-invasive molecular imaging, CIN research groups also combine MRI with
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Report to the DFG „Setting up the CIN. 2008-2010 Report“, December 2010, p. 22.
728:"www.tuebingenresearchcampus.com/research-in-tuebingen/excellence-initiative/"
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For scientists further along their career paths, the CIN has established a
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Overview article on CIN in Frankfurter Allgemeinen Zeitung, 31 May 2017
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Beside the CIN, several foundations such as the Hertie foundation, the
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methods complementing biological and cognition research approaches.
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Werner Reichardt Centrum für Integrative Neurowissenschaften (CIN)
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Several research groups at the CIN work hand-in-hand with the
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994:"www.neuroschool-tuebingen-schuelerlabor.de/index.php?id=189"
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Siegel, Markus; Donner, Tobias H.; Engel, Andreas K. (2012).
771:"Spectral fingerprints of large-scale neuronal interactions"
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Werner Reichardt Centre for Integrative Neuroscience (CIN)
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Biological data are analysed and processed using modern
756:"www.cin.uni-tuebingen.de/mission-methods/methods.html"
742:"www.cin.uni-tuebingen.de/research/research-areas.html"
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based on a former junior research group on this topic.
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379:. In these experiments, membrane potentials including
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A major contributor to this article appears to have a
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with its institutional strategy and research school.
672:"www.uni-tuebingen.de/en/excellence-initiative.html"
151:, and by adding encyclopedic content written from a
441:technique. Super resolution microscopy can reach
811:"www.kyb.tuebingen.mpg.de/research/dep/ks.html"
498:Max Planck Institute for Biological Cybernetics
421:, and to observe their behaviour in real time:
362:Max Planck Institute for Biological Cybernetics
524:in the framework of its Bernstein initiative.
825:"press release of the University of Tübingen"
8:
970:"www.neuroschool-tuebingen-schuelerlabor.de"
883:"www.cin.uni-tuebingen.de/research/ehrlich/"
502:Max Planck Institute for Intelligent Systems
264:German Center for Neurodegenerative Diseases
260:Hertie Institute for Clinical Brain Research
53:Learn how and when to remove these messages
16:Unit of the University of Tübingen, Germany
869:"www.cin.uni-tuebingen.de/research/giese/"
522:Federal Ministry of Education and Research
277:Scientific approach and research questions
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513:German Center for Diabetes Research (DZD)
336:based on neurobiological basic research.
189:Learn how and when to remove this message
171:Learn how and when to remove this message
105:Learn how and when to remove this message
1075:Neuroscience research centers in Germany
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132:contains content that is written like
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354:functional magnetic resonance imaging
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528:Support for early career researchers
205:is the common platform for systems
603:Eberhard Karls University Tübingen
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459:transcranial magnetic stimulation
425:, most importantly making use of
364:under the aegis of CIN professor
34:This article has multiple issues.
491:Local relations and partnerships
443:resolutions below the Abbe limit
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85:. Please discuss further on the
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928:"www.neuroschool-tuebingen.de/"
515:, and with the Stuttgart-based
42:or discuss these issues on the
293:etc.) impair these functions.
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383:of neurons are measured with
370:positron emission tomography
775:Nature Reviews Neuroscience
435:super-resolution microscopy
299:neuronal network structures
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628:"DFG Gepris entry for CIN"
520:(2010–2015) by the German
318:computational neuroscience
262:(HIH) on one side and the
942:"NeNa conference website"
714:"DFG Gepris entry on CIN"
583:Scientific advisory board
437:with a molecule-specific
577:Klaus Tschira foundation
573:Robert Bosch foundation
423:fluorescence microscopy
1070:University of Tübingen
402:, or by employing the
350:magnetoencephalography
346:electroencephalography
211:University of Tübingen
400:multielectrode arrays
396:single-unit recording
215:Excellence Initiative
153:neutral point of view
83:neutral point of view
1046:48.52500°N 9.05889°E
549:(“NeNa-Konferenz”).
431:2-photon microscopes
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506:learning and memory
479:, most importantly
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147:and inappropriate
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678:on 2018-08-13.
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996:(in German)
972:(in German)
841:(in German)
695:(in German)
644:(in German)
404:patch clamp
330:prosthetics
287:Parkinson's
283:Alzheimer's
271:Peter Thier
161:August 2017
95:August 2017
1064:Categories
1037:09°03′32″E
1034:48°31′30″N
1000:2017-08-04
976:2017-08-04
845:2017-08-04
699:2017-08-04
648:2017-08-04
614:References
575:, and the
517:Fraunhofer
481:philosophy
477:humanities
408:nerve cell
392:electrodes
348:(EEG) and
141:improve it
39:improve it
307:behaviour
303:cognition
228:cognition
87:talk page
45:talk page
797:22233726
538:doctoral
427:confocal
415:in vitro
439:marking
419:in vivo
398:, with
372:(PET).
340:Methods
326:imaging
245:History
209:at the
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534:master
447:axonal
385:extra-
358:Tesla
793:PMID
536:and
305:and
230:and
201:The
783:doi
429:or
417:or
394:in
387:or
291:ALS
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