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452:. Extract the pertinent information rather than just dumping low-level facts in a big list. For example, a long list of side effects is largely useless without some idea of which are common or serious. It can be illuminating to compare the drug with others in its class, or with older and newer drugs. Do not include dose or titration information except when they are extensively discussed by secondary sources, necessary for the discussion in the article, or when listing equivalent doses between different pharmaceuticals. Knowledge is also not an instruction manual or textbook and should not include instructions, advice (legal, medical or otherwise) or "how-to"s (see 95: 1388: 46: 1011:
Include information on the chemical structure, stereochemistry, and chemical composition of the drug (e.g., free base, hydrochloride salt, etc.), physical characteristics, and notable chemical properties. Basic physicochemical properties such as melting pointing, solubility and other raw data should
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Where ambiguity exists as to the order in which drugs should be listed, the British Approved Name for the combination (if one exists) or the order used by the manufacturer of the innovator brand should be used as a guide. For example, although no BAN exists for isosorbide dinitrate/hydralazine above,
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of the drug (for example which receptor subtype, ion channel population, isozyme, etc. the drug binds to) and if the drug blocks or activates that target. If relevant, mention what endogenous substance (neurotransmitter, hormone, substrate, etc.) is mimicked or blocked by the drug. Also describe
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When writing about the history of the drug, only include this section if a sufficient amount of information on the drug's origin and/or first synthesis is available. If so, there should be a timeline of first synthesis, approval dates (U.S., Europe, UK, etc.), when marketing stopped or ownership
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This section details what forms the drug is available in. Information includes route of administration (e.g. oral, i.v., i.m., rectal, parenteral, intranasal. Oral forms of administration should be differentiated: tablets, crushable tablets, capsules (containing powder, gel, or sprinkle beads),
733:(USAN), development codenames, and the pronunciation -- that content can go in the infobox or the body of the article. In parentheses, list the main or initial brand names for the drug. If there are more than a few brand names, it is best to list these separately in the body of the article. 862:
List the adverse effects (including withdrawal symptoms, if applicable), as well as whether they are common, uncommon, or rare. The latter should only be mentioned if severe or otherwise notable. If possible, use specific statistics (be sure to cite sources!). Use side effect percentage with
721:. If a substance is used primarily as a drug, it should be noted so. Most of our readers access Knowledge on mobile devices, and excess naming becomes clutter that prevents swift access to the heart of the matter. Therefore, avoid cluttering the lead with multiple alternatives to the 484:
states that, "naming should give priority to what the majority of English speakers would most easily recognize, with a reasonable minimum of ambiguity, while at the same time making linking to those articles easy and second nature." To that end, the World Health Organization
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The order of sections used in this guideline is recommended for readability and consistency between articles. The order suggested below is to emphasize information sought after by general readers. If you disagree with part of the style guide, please discuss changes on the
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to the chosen name. Non-standard proprietary combination preparations are discouraged, and fall outside the scope of this guideline. For example, a hypothetical "paracetamol/dextromethorphan/pseudoephedrine" page is discouraged and does not fall under this guideline.
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This section should go into further detail regarding what the medication is used for (for each major indication). Take special care with regulatory terms; since drug approvals vary from country to country, so does the distinction between approved and
521:, in which case the INN consists of two parts: the cation and the anion name. For example, "chlorphenamine maleate" is the INN modified (INNM) of a common first-generation antihistamine, thus the INN of the active moiety is used as the page title: 716:
without introducing errors or ambiguity. It is also reasonable to have the lead introduce content in the same order as the body of the text. In articles about drugs, they should describe the drug in question, as well as what it does. Note any
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Nonproprietary names are common nouns and hence should be lower case except in titles, the beginning of sentences, and in other situations that require capitalization. In contrast, trade names are proper nouns and should always be capitalized.
464:, intended to be read by the lay public so it is important to make technical material as accessible as possible to a wide audience but at the same time, not reducing the value of the article to more technical readers including 1218: 178: 1198:
Look for similar articles to check for what categories they belong to and add the article to any appropriate categories. If no similar articles can be found, add the article to any categories that seem appropriate. See
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is defined as "the section before the first headline. The table of contents, if displayed, appears between the lead section and the first headline." The lead of an article, if not the entire article, should be
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This section should describe the clinically relevant pharmacokinetic parameters of a drug or active metabolites and the mechanisms of clearance (e.g., specific enzyme systems or transporters). List the
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A page should mention other names in the lead section, in boldface, and the naming reference noted if possible. Those other common names of the drug should redirect to that page. For example, the page
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For articles on agents that are primarily recreational in use a section on the "Effects" of the agent early is recommended. This may be followed by sections on "Recreational uses" and "Medical uses".
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contains an updated list of of articles that don't follow this article title guideline and include the INN in the drugbox INN parameter; these articles are listed under the underscore section.
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is more appropriate. For example, "paracetamol" and "acetaminophen" are two common names for the same analgesic, and "paracetamol" is the INN. The relevant Knowledge article has the page name
143: 226: 745:, but it should be included in every drug-related article. In the source code of the article, it appears before the article lead. It is displayed at the top-right corner of the page. For 1180:
This is not a section — it comes after the last section in the article — but it is nonetheless an important part of any drug article. Most families of drugs already have a template; see
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pathways are impacted, what genes are up or down regulated, etc.) and how modulating the activity of the target ultimately translates into the desired therapeutic effect (that is, the
332: 575:("/") character. For example, the standard combination of isosorbide dinitrate and hydralazine, used to treat congestive heart failure in African Americans, is described in the page 1145: 256: 138: 1314:
There is currently no consensus whether codes for drug combinations should be added to articles about single drugs. If you do so, add "(combination with ])" or the like, using the
1149: 155: 33: 308: 429: 210: 1200: 296: 249: 713: 150: 303: 263: 205: 184: 529:. If an INN has yet to be formally listed by WHO, but a proposed INN (pINN) exists, it is considered to be equivalent to the INN with respect to this guideline. 284: 174: 1181: 592: 291: 277: 270: 197: 325: 230: 393:. It contains the articles naming conventions and the general recommended outline of an article, as well as useful information to bring an article to 795:
enteric-coated or slow-release tables/capsules, syrup, sugar-free liquid, or powder (soluble or for suspension). Only include this section if the
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dosage information is not recommended as it may be construed as medical advice and be easily subject to vandalism or uninformed good-faith edits.
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This section should cover any known drug-microbiota interactions, particularly ones that occur in the gut for orally administered medications.
1399: 934:, for example vasodilation resulting in decreased blood pressure). If the mechanism of action is not known, this section should state that. 613: 501:(INN), also known as recommended International Nonproprietary Name (rINN), if one exists, except in unusual circumstances where another 70: 898:
This section should note what other drugs/food interact with the drug in question, and what effect(s) are produced by this interaction.
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Under what circumstances should the drug in question not be used? Distinguish relative and absolute contraindications if possible.
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Full instructions are available on the page for each infobox. A suitable picture for the infobox is encouraged. For drugs, the 2D
416:(USAN) variant may also be mentioned. The initial brand name(s) follows, in parentheses. All drug names should be in boldface per 576: 698:
Primarily medication-related pages should contain information organized into the following sections, with attention to order.
1024: 646:, the chemical infobox is possibly more appropriate for research drugs for which little or no clinical data is yet available 481: 457: 1208: 730: 1141: 1126:
Avoid the See also section when possible; prefer wikilinks in the main article and navigation templates at the end.
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the manufacturer of the innovator brand "BiDil" lists the constituents in that order. Alternative names should be
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These are essential. Unreferenced "information" may be deleted or moved to the talk page. As guidelines we have
679: 655: 552: 551:. All issues of the journal, and lists of all proposed and recommended INNs from 1955 onward, are available in 1204: 954: 950: 556: 1137: 726: 624: 409: 64: 571:, this guideline encourages the use of page titles containing the active constituents separated by the 863:
placebo/control vs. percentage with drug/experimental. Always include adverse events highlighted with
962: 958: 754: 502: 1148:. In short: The popular press is generally not a reliable source for medicine information. See also 1074:
If applicable, describe recreational usage (i.e. abuse) and other illicit usage (for example, using
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should be strictly summarized, with clear linking to their main articles for further reading.
1233: 1163: 982: 922: 1228:, the content should primarily focus on what particular effects the combination has, such as 1225: 1057: 738: 568: 54: 1289: 970: 966: 946: 540:, which notes in the first sentence that "salbutamol" is the INN and "albuterol" is the 1079: 931: 708: 662:
is acceptable. The easiest way to populate the drugbox and protein templates is to use
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This section describes symptoms of overdose, what to do in case of overdose, and the
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Scientific Style and Format: the CBE Manual for Authors, Editors and Publishers
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Ongoing investigations into a medication that have not reached clinical usage
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Knowledge:Manual of Style (medicine-related articles)#Citing medical sources
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on how to format and present article content within their area of interest.
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Knowledge talk:WikiProject Pharmacology/General/Main sections of drug page
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Global sales, distribution, cost in major English speaking countries, etc.
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The article title and the first name to mention in the lead should be the
89: 1264: 746: 460:). Finally it is important to keep in mind that we are writing a general 986: 978: 974: 567:
Since no international convention exists to guide naming of standard
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for templates to choose from. Language links go right to the bottom.
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should be added to the drugbox. If there is more than one, use the
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INNs are published by the World Health Organization in the journal
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Include one or more of the following subsections if appropriate:
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The ordering of section may vary depending on the article type
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Knowledge:WikiProject Pharmacology/Workspace#Naming conventions
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Category:Infobox drug articles with non-default infobox title
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Describe regulatory status in different regions of the world.
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the downstream consequences of modulating that target (what
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Brand names of the medication and manufacturer, if notable.
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Infoboxes should be used where appropriate. These include
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articles on Knowledge, as established by the consensus of
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Avoid this section if possible, since it is a magnet for
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for an immunosuppressant) for which template(s) to use.
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Knowledge:Reliable sources (medicine-related articles)
1395:(6th ed.). Cambridge: Cambridge Univ. Press. p. 324. 1116:
If different from use in humans or otherwise notable.
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Controversies surrounding the medication, if notable.
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Knowledge:Manual of Style (medicine-related articles)
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field of the drugbox does not provide enough space.
489:(INN) should normally be used as the article name. 440:Try to avoid cloning drug formularies such as the 63:It contains the advice or opinions of one or more 1303:database. Recommended sorting of multiple codes: 1201:Knowledge:WikiProject Pharmacology/Categorization 497:A drug article should be titled according to its 591:Tasks related to this guideline can be found at 1321:Drugs without an ATC(vet) code should have set 973:and the major metabolizing enzymes for example 326: 8: 1310:Within these two groups, sort alphabetically 1182:Knowledge:WikiProject Pharmacology/Templates 1431:, and may also be found in the page's URL. 424:and family and the main therapeutic uses. 333: 319: 884:(median lethal dose), if it is available. 1166:. Links to on-line pharmacies and blogs 1389:"Chaper 19: Drugs and Pharmacokinetics" 1379: 1334: 1020:(only necessary for articles tagged by 753:. More information can be found at the 1275:parameter together with the templates 1244:Add a section listing "Agents" in the 1418:, and may be found in the page's URL. 7: 1184:and the appropriate ATC list (e. g. 678:for the protein and enter the ID in 1387:CBE Style Manual Committee (2002). 614:Knowledge:Manual of Style/Infoboxes 1056:Don't use this section for adding 750: 666:template-filling web site. Search 408:(INN) of the drug; see below. The 391:Knowledge:WikiProject Pharmacology 80:thoroughly vetted by the community 24: 18:Knowledge:WikiProject Pharmacology 1203:for categories to choose from. A 965:, major metabolic pathways (e.g. 917:If known, describe the molecular 670:for the drug and enter the ID in 499:International Nonproprietary Name 487:International Nonproprietary Name 406:International Nonproprietary Name 577:Isosorbide dinitrate/hydralazine 44: 1414:DrugBank IDs follow the format 1: 1307:ATC codes before ATCvet codes 1194:Categories and language links 714:written as simply as possible 76:Knowledge policy or guideline 458:Knowledge:Medical disclaimer 1427:HUGO IDs follow the format 1341:Notable exceptions include 1209:Category:Pharmacology stubs 1078:to facilitate robbery/as a 865:mandated prominent warnings 731:United States Approved Name 1469: 1142:Knowledge:Reliable sources 761:is able to provide images. 611: 563:Standard combination drugs 542:United States Adopted Name 444:and online resources like 414:United States Adopted Name 344: 1232:. Regular effects of the 1012:be placed in the drugbox. 658:format is preferred, but 243: 220: 165: 161: 108: 92: 1453:WikiProject Pharmacology 1448:WikiProject style advice 1299:etc.) as well as to the 1221:for related discussion. 1034:Detection in body fluids 797:Routes of administration 921:including the specific 1176:Navigational templates 951:volume of distribution 755:template documentation 741:This is not a section 536:redirects to the page 436:General considerations 227:Requested articles (1) 98: 1138:Knowledge:Attribution 1025:WikiProject Chemicals 727:British Approved Name 612:Further information: 410:British Approved Name 381:for the structure of 292:Resources for editors 97: 78:, as it has not been 995:Pharmacomicrobiomics 805:Specific populations 549:WHO Drug Information 509:, and a redirect at 480:Knowledge policy on 109:General information 1252:Recreational agents 1052:Society and culture 928:signal transduction 919:mechanism of action 909:Mechanism of action 519:quaternary compound 493:Articles to use INN 1234:active ingredients 820:Labor and delivery 725:name, such as the 719:black box warnings 527:Tiotropium bromide 472:, and scientists. 257:Structure diagrams 99: 1401:978-0-521-47154-1 1323:ATC_prefix = none 1226:combination drugs 1046:transferred, etc. 983:monoamine oxidase 923:biological target 890:Drug interactions 844:Contraindications 569:combination drugs 482:naming convention 343: 342: 216: 215: 88: 87: 1460: 1432: 1430: 1425: 1419: 1417: 1412: 1406: 1405: 1384: 1367: 1339: 1324: 1317: 1316:ATC_supplemental 1294: 1288: 1284: 1278: 1274: 1273:ATC_supplemental 1072:Recreational use 1029: 1023: 940:Pharmacokinetics 913:Pharmacodynamics 780:, further down. 641: 638:Infobox chemical 628: 399:featured article 371: 364: 357: 335: 328: 321: 163: 139:Reliable sources 90: 74:is not a formal 71:This information 48: 41: 1468: 1467: 1463: 1462: 1461: 1459: 1458: 1457: 1438: 1437: 1436: 1435: 1428: 1426: 1422: 1415: 1413: 1409: 1402: 1386: 1385: 1381: 1376: 1371: 1370: 1340: 1336: 1331: 1322: 1315: 1292: 1286: 1282: 1276: 1272: 1262: 1254: 1242: 1060:to the article. 1027: 1021: 955:protein binding 947:bioavailability 882: 854:Adverse effects 790:Available forms 696: 688: 635: 622: 616: 610: 601: 565: 495: 478: 466:medical doctors 438: 420:. Indicate the 375: 374: 367: 360: 353: 349: 339: 206:Editor outreach 127:Manual of Style 84: 83: 28:For the parent 22: 21: 20: 12: 11: 5: 1466: 1464: 1456: 1455: 1450: 1440: 1439: 1434: 1433: 1420: 1407: 1400: 1378: 1377: 1375: 1372: 1369: 1368: 1362: 1333: 1332: 1330: 1327: 1312: 1311: 1308: 1261: 1258: 1253: 1250: 1241: 1238: 1215: 1214: 1213: 1212: 1191: 1190: 1189: 1173: 1172: 1171: 1158:External links 1155: 1154: 1153: 1129: 1128: 1127: 1119: 1118: 1117: 1112:Veterinary use 1109: 1103: 1102: 1101: 1095: 1089: 1083: 1080:date rape drug 1069: 1062: 1061: 1049: 1048: 1047: 1038: 1037: 1036: 1031: 1014: 1013: 1004: 1003: 1002: 1001: 1000: 992: 991: 990: 937: 936: 935: 932:mode of action 901: 900: 899: 887: 886: 885: 880: 870: 869: 868: 851: 850: 849: 841: 840: 839: 838: 837: 835:In the elderly 832: 827: 822: 817: 811: 810: 802: 801: 800: 786: 785: 774:off-label uses 764: 763: 762: 735: 734: 695: 692: 687: 684: 648: 647: 642:– for example 633: 629:– for example 609: 606: 600: 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355:WP:DRUGLIKE 264:Photographs 167:Departments 101:WikiProject 53:This is an 1442:Categories 1374:References 1347:amfetamine 1132:References 585:redirected 538:Salbutamol 422:drug class 387:medication 285:Historical 175:Assessment 1416:APRDxxxxx 1343:lysergide 1265:ATC codes 1260:ATC codes 1086:Economics 1058:WP:TRIVIA 1018:Synthesis 1007:Chemistry 963:clearance 959:half-life 825:Lactation 815:Pregnancy 747:ATC codes 729:(BAN) or 680:this page 672:this page 664:Diberri's 652:structure 608:Infoboxes 534:Albuterol 450:Drugs.com 430:talk page 412:(BAN) or 347:Shortcuts 278:Workspace 271:Templates 30:guideline 1122:See also 1106:Research 971:phase II 873:Overdose 782:Detailed 686:Sections 668:DrugBank 544:(USAN). 517:it is a 456:and the 401:status. 193:Research 1041:History 969:and/or 967:phase I 739:Drugbox 555:on the 1357:, and 1290:ATCvet 987:UGT2B7 979:CYP3A4 975:CYP2D6 749:, see 743:per se 515:unless 446:RxList 32:, see 1329:Notes 1246:class 751:below 573:slash 59:style 55:essay 16:< 1397:ISBN 1285:and 1267:and 1224:For 1168:will 1164:spam 1144:and 707:The 703:Lead 676:HUGO 448:and 385:and 383:drug 309:talk 297:talk 211:talk 198:talk 185:talk 156:talk 144:talk 132:talk 120:talk 1301:WHO 1280:ATC 911:or 892:or 856:or 723:INN 660:PNG 656:SVG 654:in 553:PDF 442:BNF 397:or 231:(2) 179:Log 57:on 1444:: 1391:. 1353:, 1349:, 1345:, 1325:. 1293:}} 1287:{{ 1283:}} 1277:{{ 1248:. 1140:, 1082:). 1028:}} 1022:{{ 985:, 981:, 977:, 961:, 957:, 953:, 949:, 881:50 879:LD 757:. 682:. 640:}} 636:{{ 627:}} 623:{{ 595:. 579:. 559:. 468:, 432:. 229:/ 204:→ 191:→ 181:) 173:→ 1404:. 1152:. 1030:) 867:. 334:e 327:t 320:v 177:( 82:. 61:. 36:.

Index

Knowledge:WikiProject Pharmacology
guideline
Knowledge:Manual of Style (medicine-related articles)

essay
style
WikiProjects
This information
Knowledge policy or guideline
thoroughly vetted by the community

WikiProject
Pharmacology

Project page
talk
Manual of Style
talk
Reliable sources
talk
Popular pages
talk
Assessment
Log
talk
Research
talk
Editor outreach
talk
Requested articles (1)
(2)
Cleanup list

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