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Wim Crusio

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471:, depressive-like behaviors, and learning, with a concomitant drop in neurogenesis. However, the results were strain- and sex-specific and there did not appear to be a clear-cut correlation between the different changes, so that they finally concluded that although their data do not disprove the idea that deficits in hippocampal neurogenesis solely underlie the behavioral impairments observed in human psychiatric disorders such as depression, they do not provide support for this hypothesis either. 3238: 741: 38: 543:, which he edited from 2001 to 2011. The standards for the publication of mouse mutant studies that he and his co-editors developed for this journal are gradually being accepted in the field. Since 2017, Crusio is the editor-in-chief of 709:(1998–2001). In 2011 he received from this society the "Distinguished Service Award", which is given for exceptional contributions to the field of behavioral neurogenetics. Crusio also served on the executive committees of the 462:
might underlie depression, Crusio and collaborators undertook a series of experiments investigating changes in behavior and neurogenesis in mice that had undergone UCMS. They showed dramatic changes in levels of
426:(IIPMF) correlated with learning performance. Together with Herbert Schwegler and Hans-Peter Lipp, Crusio showed that an inverse correlation, that is, animals with larger IIPMF learn better, could be found for 3364: 520:
gene) has been invalidated. A review of the findings obtained with these mice in many different laboratories did indeed indicate that these animals display autistic-like symptoms, especially changes in
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Schwegler, H; Crusio, W. E.; Brust, I (1990). "Hippocampal mossy fibers and radial-maze learning in the mouse: a correlation with spatial working memory but not with non-spatial reference memory".
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Crusio, W. E.; Schwegler, H.; van Abeelen, J. H. F. (February 1989). "Behavioral responses to novelty and structural variation of the hippocampus in mice. II. Multivariate genetic analysis".
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Crusio, W. E.; Schwegler, H.; Lipp, H. P. (November 1987). "Radial-maze performance and structural variation of the hippocampus in mice: a correlation with mossy fibre distribution".
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Crusio, W. E.; Schwegler, H; Lipp, H. P. (November 1987). "Radial-maze performance and structural variation of the hippocampus in mice: a correlation with mossy fibre distribution".
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revision, which was originally published in 1979, was translated in German and continues to engender interest. For his PhD thesis, Crusio studied the inheritance of the effects of
725:, and has been a President of the Dutch Behavior Genetics Contact Group. He has been a member of several program committees for scientific meetings, most notably the 8th and 10th 698: 3007: 272: 163: 2804: 2100: 1638:
Kempermann, G; Kronenberg, G (September 2003). "Depressed new neurons--adult hippocampal neurogenesis and a cellular plasticity hypothesis of major depression".
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Mineur, Y. S.; Belzung, C; Crusio, W. E. (December 2007). "Functional implications of decreases in neurogenesis following chronic mild stress in mice".
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Crusio, W. E.; Genthner-Grimm, G.; Schwegler, H. (July 1986). "A quantitative-genetic analysis of hippocampal variation in the mouse".
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Crusio, W. E.; Genthner-Grimm, G.; Schwegler, H. (2007). "A quantitative-genetic analysis of hippocampal variation in the mouse".
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task. Taken together, Crusio and collaborators think that it is highly likely that this correlation is
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Spencer, C. M.; Alekseyenko, O; Serysheva, E; Yuva-Paylor, L. A.; Paylor, R (October 2005).
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and the 2008, 2009 (co-chair), 2010 (chair), and 2011 (chair) Annual Meetings of the IBNS.
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Mineur, Y. S.; Huynh, L. X.; Crusio, W. E. (March 2006). "Social behavior deficits in the
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BrĂĽnner, Gerhard (1987). "Crusio, Wim: Die Gattung Anubias (Araceae)". FĂĽr Ihre BĂĽcherei.
610: 574: 534: 522: 431: 353:. He then returned to Heidelberg as a senior research scientist before being recruited as 226: 109: 3289: 665:(with Catherine Belzung and Robert Gerlai). Together with Robert Gerlai he also edited a 3243: 2563:
Belzung C, Crusio WE, Gerlai RT (January 2002). Belzung C, Crusio WE, Gerlai RT (eds.).
746: 3210: 2565:"Special issue: Behavioral neurogenetics, the genetic dissection of brain and behavior" 2287: 1962: 1935: 1891: 1855: 1509: 1480: 1349: 1083:"Protokoll der Mitgliederversammlung 2009 des Arbeitskreises Wasserpflanzen in Dresden" 849: 764: 714: 485: 451: 221: 64: 3273: 2722: 2694: 2580: 2470: 2419: 2344: 1653: 1289: 1128:
Olfaction and behavioral responses to novelty in mice: A quantitative-genetic analysis
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Olfaction and behavioral responses to novelty in mice: a quantitative-genetic analysis
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Crusio W. E. (November 2001). "Genetic dissection of mouse exploratory behaviour".
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What's Wrong with My Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice
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Crusio WE, Routtenberg A (February 2001). Routtenberg A, Crusio WE (eds.).
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Mineur, Y. S.; Prasol, D. J.; Belzung, C; Crusio, W. E. (September 2003).
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Misbehaving Science. Controversy and the Development of Behavior Genetics
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Handbook of Molecular-Genetic Techniques for Brain and Behavior Research
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Crusio, W. E.; Goldowitz, D.; Holmes, A.; Wolfer, D. (February 2009).
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Mouse Behavioral Testing: How to Use Mice in Behavioral Neuroscience
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Crusio, W. E.; Goldowitz, D; Holmes, A; Wolfer, D (February 2009).
1266:(in French). Institut des Neurosciences de Bordeaux. Archived from 687:
Behavioral Genetics of the Mouse: Genetics of Behavioral Phenotypes
1685:"Agonistic behavior and unpredictable chronic mild stress in mice" 496:. This idea is based on the fact that patients suffering from the 479:
More recently, Crusio has been investigating the possibility that
342: 167: 102: 767:, Crusio's works have been cited over 10,000 times and he has an 458:
in humans. As it had been suggested that deficits in hippocampal
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knockout mice: a model to study fragile X mental retardation".
422:, in particular the sizes of their intra- and infrapyramidal 2345:"Special issue: The neurobehavioral genetics of aggression" 3157: 2681:
Skoulakis, Efthimios M.C. (2001). "A tool for synthesis".
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Mineur, Y. S.; Belzung, C; Crusio, W. E. (November 2006).
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Morris, R. (2007). "Theories of hippocampal function". In
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French National Centre for Scientific Research scientists
3154:"Xth World Congress on Psychiatric Genetics – Committees" 2849:. Cambridge, United Kingdom: Cambridge University Press. 2709:
Skoulakis, Efthimios M.C (2001). "A tool for synthesis".
1556:. Oxford, UK: Oxford University Press. pp. 581–713. 1109:
Announcement of re-issue on CD of 1987 German edition of
389:, returning to the CNRS in 2005 as a group leader in the 2506:"Special Issue: Gene Targeting and Hippocampal Function" 1264:"Nouvel arrivant Ă  l'INB, aujourd'hui : Wim CRUSIO" 2124:"Standards for the publication of mouse mutant studies" 1936:"Fmr1 KO mice as a possible model of autistic features" 966:"Standards for the publication of mouse mutant studies" 2453:
Gerlai RT (August 2001). Gerlai RT, Crusio WE (eds.).
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by the CNRS, initially working in an institute of the
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Crusio received his bachelor's degree in biology from
2737:"Series – Cambridge Handbooks in Behavioral Genetics" 2036:"Altered anxiety-related and social behaviors in the 1885:
The Dutch-Belgian Fragile X Consortium (July 1994). "
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International Behavioural and Neural Genetics Society
232: 215: 203: 185: 151: 130: 115: 93: 83: 75: 47: 23: 2343:Crusio, Wim E. (September 1996). Crusio WE (ed.). 697:In 1996, Crusio was one of two co-founders of the 391:Centre de Neurosciences IntĂ©gratives et Cognitives 2250:"Preparing your manuscript – Research – Criteria" 573:(2002-2011). Crusio serves or has served on the 2903:"Past Officers and Executive Committee Members" 2764:"Book review: Behavioral Genetics of the Mouse" 2314:"Advances in Experimental Medicine and Biology" 1835: 1833: 1831: 1740: 1738: 273:French National Centre for Scientific Research 164:French National Centre for Scientific Research 723:International Behavioral Neuroscience Society 552:Advances in Experimental Medicine and Biology 438:, although this is not universally accepted. 8: 2847:"Cambridge Handbooks in Behavioral Genetics" 633:. He edited special issues for the journals 2040:knockout mouse model of fragile X syndrome" 2208:"Troublesome variability in mouse studies" 1479:Crusio, W. E.; Schwegler, H (April 2005). 715:Glayde Whitney's 1995 presidential address 679:Cambridge Handbooks in Behavioral Genetics 383:University of Massachusetts Medical School 339:Alexander von Humboldt Research Fellowship 180:University of Massachusetts Medical School 36: 20: 3129: 2779: 2225: 2182: 2139: 2057: 1961: 1951: 1764: 1508: 1498: 983: 2959:"Call for 2011 IBANGS award nominations" 2805:Annali dell'Istituto Superiore di SanitĂ  1021: 1019: 727:World Congresses of Psychiatric Genetics 414:Crusio and his collaborators found that 325:. From 1984 to 1987, Crusio worked as a 3290:"Wim Crusio – Google Scholar Citations" 1015: 446:When mice are exposed to unpredictable 361:(Paris V) and later moving to the CNRS 2743:from the original on 25 September 2015 2603:from the original on 24 September 2015 2485:from the original on 24 September 2015 2294:from the original on 19 September 2020 1446:. John Wiley & Sons. p. 138. 713:(from which he resigned in protest to 630:Current Opinion in Behavioral Sciences 341:. During 1988, Crusio spent a year in 291:in 1975, where he went on to obtain a 3112:"Obituary Sjeng Kerbusch (1947-1991)" 2662:from the original on 17 December 2013 2324:from the original on 30 November 2019 1135:: Krips Repro. pp. viii+146+78. 681:, a series of handbooks published by 349:, supported by a fellowship from the 7: 3180:"IBNS Committees/Mission Statements" 2544:from the original on 22 October 2012 1934:Bernardet, M; Crusio, W. E. (2006). 1296:from the original on 21 October 2014 1158: 1156: 1154: 771:of 46. Some significant papers are: 719:European Brain and Behaviour Society 603:Frontiers in Behavioral Neuroscience 299:in 1979 and 1984, respectively. His 3010:from the original on 2 October 2021 2996:. Berlin: Springer. pp. 3–11. 2853:from the original on 2 October 2021 2383:from the original on 25 August 2017 1139:from the original on 14 August 2016 555:. He is also an academic editor of 3355:Radboud University Nijmegen alumni 3065:from the original on 14 March 2012 2827:from the original on 8 August 2016 2434:from the original on 13 March 2013 2091:"The order in a billion sequences" 1856:10.1016/j.neuroscience.2007.09.045 1619:from the original on 30 April 1999 561:and served as associate editor of 119:IBANGS Distinguished Service Award 14: 3360:UMass Chan Medical School faculty 2909:from the original on 9 March 2012 2402:Crusio WE, ed. (September 1998). 2103:from the original on 3 April 2012 1215:"Liste des boursiers 1987/1988". 786:(4, Special Retrospective Issue: 607:Journal of Visualized Experiments 313:of mice, and more in general the 3236: 2260:from the original on 3 June 2021 2174:European Journal of Neuroscience 2141:10.1111/j.1601-183X.2008.00438.x 2059:10.1111/j.1601-183X.2005.00123.x 1816:from the original on 3 June 2016 1460:from the original on 10 May 2016 1324:Presses Universitaires de France 1164:"Curriculum Vitae Wim E. Crusio" 1027:"Wim E. Crusio Curriculum Vitae" 985:10.1111/j.1601-183X.2008.00438.x 739: 579:Behavioral and Brain Functions, 500:, caused by a deficiency of the 97:Behavioral neurogenetics of the 16:Dutch behavioral neurogeneticist 2622:Crusio, WE; Gerlai, RT (1999). 1802:. Academic Press. p. 166. 1036:. February 2016. Archived from 677:. Currently, he is editing the 317:of exploratory behavior, using 2990:"History of behavior genetics" 2988:Loehlin, John (1 April 2009). 2739:. Cambridge University Press. 2284:Behavioral and Brain Functions 2254:Behavioral and Brain Functions 1486:Behavioral and Brain Functions 1218:Annales de la Fondation Fyssen 546:Behavioral and Brain Functions 1: 3380:Founders of learned societies 3345:21st-century Dutch biologists 3340:20th-century Dutch biologists 2994:Handbook of Behavior Genetics 2723:10.1016/S1471-4914(01)01956-6 2695:10.1016/S0166-2236(00)01670-2 2581:10.1016/S0361-9230(01)00629-3 2471:10.1016/S0031-9384(01)00583-2 2420:10.1016/S0166-4328(97)00203-9 1654:10.1016/S0006-3223(03)00319-6 941:10.1016/S0166-4328(01)00280-7 902:10.1016/S0166-4328(89)80075-0 711:Behavior Genetics Association 685:, of which the first volume, 564:Behavioral and Brain Sciences 271:(research director) with the 3375:21st-century Dutch botanists 3370:20th-century Dutch botanists 2711:Trends in Molecular Medicine 2206:Editorial (September 2009). 1940:The Scientific World Journal 1905:10.1016/0092-8674(94)90569-X 1408:10.1016/0306-4522(90)90139-U 1363:10.1016/0006-8993(87)90498-7 1322:. Que sais-je? (in French). 1095:(4): 150–151. Archived from 863:10.1016/0006-8993(87)90498-7 788:The Origins of Neurogenetics 570:The Scientific World Journal 549:and since 2019 co-editor of 234:Author abbrev. (botany) 216:Other academic advisors 3395:Dutch expatriates in France 3035:University of Chicago Press 2795:Michetti, Caterina (2014). 1577:Willner P (December 1997). 1239:(in French). Archived from 525:, a key symptom of autism. 488:might perhaps be used as a 289:Radboud University Nijmegen 156:Radboud University Nijmegen 88:Radboud University Nijmegen 3416: 3400:Behavioral neuroscientists 3350:People from Bergen op Zoom 3325:Scientific journal editors 3085:"IBNS History of Officers" 2992:. In Kim, Yong-Kyu (ed.). 2408:Behavioural Brain Research 2089:Pagel, Mark (7 May 2004). 1992:Behavioural Brain Research 1796:Wahlsten, Douglas (2010). 1752:Behavioural Brain Research 1081:Klix, Wolf-Dieter (2009). 928:Behavioural Brain Research 889:Behavioural Brain Research 683:Cambridge University Press 639:Behavioural Brain Research 587:Behavioural Brain Research 369:, having been promoted to 337:Science Fellowship and an 255:on 20 December 1954) is a 253:Wilhelmus Elisabeth Crusio 110:neuropsychiatric disorders 31:Wilhelmus Elisabeth Crusio 2768:Genes, Brain and Behavior 2762:Mandillo, Silvia (2014). 2128:Genes, Brain and Behavior 2045:Genes, Brain and Behavior 2005:10.1016/j.bbr.2005.11.004 1766:10.1016/j.bbr.2006.07.029 1320:La Biologie de la MĂ©moire 971:Genes, Brain and Behavior 832:10.3109/01677068609106850 796:10.1080/01677060701715827 540:Genes, Brain and Behavior 504:gene often show autistic 456:major depressive disorder 442:Mouse model of depression 373:. In 2000 he became full 359:UniversitĂ© RenĂ© Descartes 242: 123: 35: 30: 3059:"Past committee members" 3029:Panofsky, Aaron (2014). 820:Journal of Neurogenetics 779:Journal of Neurogenetics 418:variations in the mouse 410:Hippocampal mossy fibers 387:Worcester, Massachusetts 331:University of Heidelberg 160:University of Heidelberg 2683:Trends in Neurosciences 2569:Brain Research Bulletin 2459:Physiology and Behavior 2193:10.1111/(ISSN)1460-9568 1706:10.1023/A:1025770616068 675:behavioral neuroscience 662:Brain Research Bulletin 643:Physiology and Behavior 624:Physiology and Behavior 533:Crusio is the founding 146:behavioral neuroscience 42:Wim Crusio, August 2006 2634:. pp. xxvii+965. 2096:Times Higher Education 816:Original publication: 371:directeur de recherche 268:directeur de recherche 3335:Dutch neuroscientists 3110:Crusio, W.E. (1991). 2171:"Author Guidelines". 1641:Biological Psychiatry 1597:10.1007/s002130050456 1500:10.1186/1744-9081-1-3 475:Mouse model of autism 3330:Behavior geneticists 3160:on 30 September 2002 2818:10.4415/ANN_14_04_14 1953:10.1100/tsw.2006.220 1554:The Hippocampus Book 1316:Chapouthier, Georges 1196:on 27 September 2011 529:Editorial activities 321:methods such as the 319:quantitative-genetic 315:genetic architecture 311:exploratory behavior 283:Education and career 219:Bram van Overbeeke, 3091:on 21 November 2008 2227:10.1038/nn0909-1075 2213:Nature Neuroscience 1438:Crawley, Jacqueline 1125:Crusio, WE (1984). 355:chargĂ© de recherche 3276:on 21 October 2014 3131:10.1007/BF01066721 2522:10.1002/hipo.10001 2361:10.1007/BF02359749 2256:. BioMed Central. 1584:Psychopharmacology 1243:on 30 October 2007 1170:on 30 January 2017 1043:on 7 November 2017 1034:Wim E. Crusio Blog 749:has a profile for 733:Significant papers 599:BMC Research Notes 498:Fragile X syndrome 176:Talence (Bordeaux) 3117:Behavior Genetics 3044:978-0-226-05831-3 3003:978-0-387-76726-0 2969:on 1 October 2011 2939:on 1 October 2011 2781:10.1111/gbb.12125 2641:978-0-444-50239-1 2349:Behavior Genetics 2280:"Editorial Board" 1693:Behavior Genetics 1563:978-0-19-510027-3 1099:on 7 October 2010 755: 693:Community service 671:molecular genetic 657:Aryeh Routtenberg 635:Behavior Genetics 581:Behavior Genetics 351:Fyssen Foundation 333:, supported by a 246: 245: 125:Scientific career 3407: 3301: 3299: 3297: 3292:. Google Scholar 3285: 3283: 3281: 3240: 3239: 3223: 3222: 3220: 3218: 3202: 3196: 3195: 3193: 3191: 3182:. Archived from 3176: 3170: 3169: 3167: 3165: 3156:. Archived from 3150: 3144: 3143: 3133: 3107: 3101: 3100: 3098: 3096: 3087:. Archived from 3081: 3075: 3074: 3072: 3070: 3055: 3049: 3048: 3037:. pp. 3–4. 3026: 3020: 3019: 3017: 3015: 2985: 2979: 2978: 2976: 2974: 2965:. 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Index


Bergen op Zoom
Netherlands
Radboud University Nijmegen
hippocampus
mouse
models
neuropsychiatric disorders
behavioral
neural
genetics
behavioral neuroscience
Radboud University Nijmegen
University of Heidelberg
French National Centre for Scientific Research
Paris
Orleans
Talence (Bordeaux)
University of Massachusetts Medical School
Thesis
Olfaction and behavioral responses to novelty in mice: a quantitative-genetic analysis
Doctoral advisor
Hans van Abeelen
Hendrik de Wit
Victor Westhoff
Author abbrev. (botany)
Dutch
behavioral
neurogeneticist
directeur de recherche

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