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The influence of p-nitrophenyl beta-d-xyloside on the synthesis of proteochondroitin sulfate by slices of embryonic chick cartilage.,Okayama M, Kimata K, Suzuki S.,J Biochem. 1973 Nov;74(5):1069-73. (
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Beta-D-xylosides consist of a xylose in beta linkage to an aglycone. The aglycone often consists of a hydrophobic compound which aids in carrying the sugar moiety to the
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Beta-D-xylosides prime chondroitin sulfate or dermatan sulfate whereas priming of heparin sulfate poorly, except with the appropriate aglycones.
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side chains, depending on the tissue. However, in 1973 it was determined that synthetic B-D-xylosides can prime
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Most of the material created from Beta-D-xylosides priming is excreted into the growth media.
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Many Beta-D-xylosides have been studied for use as xylose primes with varying results.
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residue in core proteins. This natural primer acts as a template for the assembly of
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The most active xyloside primers contain O or S in glycosidic linkage.
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Priming activity correlates with the activity of the aglycone (cite).
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161:(GAG) synthesis by substituting for the core xylosylated protein.
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284:http://jb.oxfordjournals.org/cgi/reprint/74/5/1069
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129:(PG) synthesis is initiated by the transfer of
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48:introducing citations to additional sources
168:Priming requires the Beta-anomer of xylose.
180:Beta-D-xylosides prime GAGs in most cells.
38:Relevant discussion may be found on the
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194:where GAG synthesis takes place.
31:relies largely or entirely on a
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300:Glycosides by glycone type
177:Priming is dose dependent.
222:Esko and Montgomery 1995
204:2-naphthol-B-D-xyloside
119:derived from the sugar
261:Lugemwa and Esko 1991
231:Galligani et al. 1975
44:improve this article
151:chondroitin sulfate
240:Sobue et al. 1987
198:List of xylosides
159:glycosaminoglycan
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155:dermatan sulfate
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143:heparin sulfate
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192:golgi membrane
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33:single source
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127:Proteoglycan
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210:References
135:UDP-xylose
70:newspapers
59:"Xyloside"
117:glycoside
40:talk page
294:Category
131:D-xylose
113:xyloside
100:May 2010
147:heparin
84:scholar
274:, 1994
272:et al.
270:Fritz
153:, and
139:serine
121:xylose
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137:to a
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91:JSTOR
77:books
63:news
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