Knowledge (XXG)

XPOT

Source πŸ“

242: 219: 116: 141: 493: 248: 147: 1560: 255: 154: 691: 672: 77: 1629: 1605: 1624: 1080: 1062: 241: 922: 915: 218: 1343:"Steady-state nuclear localization of exportin-t involves RanGTP binding and two distinct nuclear pore complex interaction domains" 1191: 1049: 1028: 140: 115: 1045: 1024: 57: 254: 153: 1598: 247: 146: 736: 65: 1439:"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" 717: 1591: 129: 1482:"1,25-Dihydroxyvitamin D3 suppresses exportin expression in human promyelocytic leukemia HL-60 cells" 1397: 44: 898: 894: 890: 886: 839: 835: 831: 827: 1098:
Kutay U, Lipowsky G, Izaurralde E, Bischoff FR, Schwarzmaier P, Hartmann E, Gorlich D (Jul 1998).
1170: 89: 1386:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" 1298:"Identification of two novel RanGTP-binding proteins belonging to the importin beta superfamily" 865: 806: 1538: 1503: 1468: 1425: 1372: 1329: 1284: 1241: 1162: 1121: 37: 1575: 1528: 1493: 1458: 1450: 1415: 1405: 1362: 1354: 1319: 1309: 1274: 1266: 1231: 1223: 1152: 1111: 334: 265: 209: 164: 1324: 492: 309: 85: 1401: 1279: 1254: 1236: 1211: 1463: 1438: 1420: 1385: 1367: 1342: 1157: 1140: 1116: 1099: 999:
from the nucleus to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once
606: 601: 596: 580: 575: 570: 565: 560: 555: 539: 534: 1618: 1571: 1358: 521: 1174: 69: 996: 327: 106: 93: 1270: 1085:
National Center for Biotechnology Information, U.S. National Library of Medicine
1067:
National Center for Biotechnology Information, U.S. National Library of Medicine
1000: 1227: 410: 992: 226: 123: 73: 1498: 1481: 636: 470: 348: 293: 280: 192: 179: 81: 1542: 1507: 1472: 1429: 1410: 1376: 1333: 1314: 1297: 1288: 1245: 1166: 1125: 962: 957: 1533: 1516: 946: 781: 762: 1454: 978: 748: 703: 1192:"Entrez Gene: XPOT exportin, tRNA (nuclear export receptor for tRNAs)" 1255:"Export and transport of tRNA are coupled to a multi-protein complex" 930: 658: 1559: 1212:"The role of exportin-t in selective nuclear export of mature tRNAs" 1517:"Interaction of immobilized human exportin-t with calf liver tRNA" 621: 617: 1567: 985: 501: 61: 1384:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
1100:"Identification of a tRNA-specific nuclear export receptor" 1253:
Kruse C, Willkomm DK, GrΓΌnweller A, et al. (2000).
317: 1579: 1437:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
1141:"Identification of a nuclear export receptor for tRNA" 1341:
Kuersten S, Arts GJ, Walther TC, et al. (2002).
1296:
Kutay U, Hartmann E, Treichel N, et al. (2001).
482: 1480:
Suzuki T, Koyama Y, Hayakawa S, et al. (2006).
879: 858: 820: 799: 1210:Arts GJ, Kuersten S, Romby P, et al. (1999). 1041: 1039: 1037: 1020: 1018: 1016: 264: 163: 16:Protein-coding gene in the species Homo sapiens 1046:GRCm38: Ensembl release 89: ENSMUSG00000034667 1599: 991:This gene encodes a protein belonging to the 8: 1139:Arts GJ, Fornerod M, Mattaj IW (May 1998). 1025:GRCh38: Ensembl release 89: ENSG00000184575 1606: 1592: 632: 517: 305: 204: 101: 1532: 1497: 1462: 1419: 1409: 1366: 1323: 1313: 1278: 1235: 1156: 1115: 1186: 1184: 995:exportin family that mediates export of 1012: 1003:has bound both tRNA and GTP-bound RAN. 18: 269: 230: 225: 168: 127: 122: 7: 1556: 1554: 1578:. You can help Knowledge (XXG) by 876: 855: 817: 796: 772: 753: 727: 708: 682: 663: 487: 405: 343: 322: 14: 981:that in humans is encoded by the 1558: 1359:10.1128/MCB.22.16.5708-5720.2002 491: 253: 246: 240: 217: 152: 145: 139: 114: 597:intracellular protein transport 1630:Human chromosome 12 gene stubs 1325:11858/00-001M-0000-0015-3D4E-B 502:More reference expression data 471:More reference expression data 1: 1158:10.1016/S0960-9822(98)70130-7 1117:10.1016/S1097-2765(00)80036-2 238: 137: 1625:Genes on human chromosome 12 1390:Proc. Natl. Acad. Sci. U.S.A 602:tRNA re-export from nucleus 359:stromal cell of endometrium 1646: 1553: 923:Chr 10: 121.42 – 121.46 Mb 1271:10.1042/0264-6021:3460107 1081:"Mouse PubMed Reference:" 1063:"Human PubMed Reference:" 961: 956: 952: 945: 929: 910: 883: 862: 851: 824: 803: 792: 779: 775: 760: 756: 747: 734: 730: 715: 711: 702: 689: 685: 670: 666: 657: 642: 635: 631: 615: 520: 516: 499: 490: 481: 468: 457:medullary collecting duct 417: 408: 355: 346: 316: 308: 304: 287: 274: 237: 216: 207: 203: 186: 173: 136: 113: 104: 100: 55: 52: 48:, XPO3, exportin for tRNA 42: 35: 30: 26: 21: 1515:Li S, Sprinzl M (2007). 1228:10.1093/emboj/17.24.7430 607:tRNA export from nucleus 1499:10.2220/biomedres.27.89 916:Chr 12: 64.4 – 64.45 Mb 1411:10.1073/pnas.242603899 1315:10.1074/jbc.M006242200 391:middle temporal gyrus 232:Chromosome 10 (mouse) 130:Chromosome 12 (human) 1534:10.4161/rna.3.4.3679 1402:2002PNAS...9916899M 395:ganglionic eminence 371:islet of Langerhans 1566:This article on a 1455:10.1101/gr.2596504 737:ENSMUSG00000034667 590:Biological process 549:Cellular component 528:Molecular function 1587: 1586: 1396:(26): 16899–903. 972: 971: 968: 967: 941: 940: 906: 905: 873: 872: 847: 846: 814: 813: 788: 787: 769: 768: 743: 742: 724: 723: 698: 697: 679: 678: 627: 626: 512: 511: 508: 507: 477: 476: 464: 463: 402: 401: 379:bone marrow cells 300: 299: 199: 198: 1637: 1608: 1601: 1594: 1562: 1555: 1546: 1536: 1511: 1501: 1476: 1466: 1433: 1423: 1413: 1380: 1370: 1337: 1327: 1317: 1292: 1282: 1249: 1239: 1196: 1195: 1188: 1179: 1178: 1160: 1136: 1130: 1129: 1119: 1095: 1089: 1088: 1077: 1071: 1070: 1059: 1053: 1043: 1032: 1022: 954: 953: 925: 918: 901: 877: 868: 856: 852:RefSeq (protein) 842: 818: 809: 797: 773: 754: 728: 709: 683: 664: 633: 518: 504: 495: 488: 473: 453:substantia nigra 413: 411:Top expressed in 406: 387:body of pancreas 383:ventricular zone 367:Brodmann area 23 363:endothelial cell 351: 349:Top expressed in 344: 323: 306: 296: 283: 272: 257: 250: 244: 233: 221: 205: 195: 182: 171: 156: 149: 143: 132: 118: 102: 96: 94:XPOT - orthologs 47: 40: 19: 1645: 1644: 1640: 1639: 1638: 1636: 1635: 1634: 1615: 1614: 1613: 1612: 1551: 1549: 1514: 1479: 1449:(10B): 2121–7. 1436: 1383: 1353:(16): 5708–20. 1347:Mol. Cell. Biol 1340: 1308:(51): 40163–8. 1295: 1252: 1222:(24): 7430–41. 1209: 1205: 1203:Further reading 1200: 1199: 1190: 1189: 1182: 1138: 1137: 1133: 1097: 1096: 1092: 1079: 1078: 1074: 1061: 1060: 1056: 1044: 1035: 1023: 1014: 1009: 963:View/Edit Mouse 958:View/Edit Human 921: 914: 911:Location (UCSC) 897: 893: 889: 885: 864: 838: 834: 830: 826: 805: 718:ENSG00000184575 611: 585: 544: 500: 469: 460: 455: 451: 447: 443: 439: 435: 433:renal corpuscle 431: 427: 423: 409: 398: 393: 389: 385: 381: 377: 375:Achilles tendon 373: 369: 365: 361: 347: 291: 278: 270: 260: 259: 258: 251: 231: 208:Gene location ( 190: 177: 169: 159: 158: 157: 150: 128: 105:Gene location ( 56: 43: 36: 17: 12: 11: 5: 1643: 1641: 1633: 1632: 1627: 1617: 1616: 1611: 1610: 1603: 1596: 1588: 1585: 1584: 1563: 1548: 1547: 1512: 1477: 1434: 1381: 1338: 1293: 1250: 1206: 1204: 1201: 1198: 1197: 1180: 1131: 1090: 1072: 1054: 1033: 1011: 1010: 1008: 1005: 970: 969: 966: 965: 960: 950: 949: 943: 942: 939: 938: 936: 934: 927: 926: 919: 912: 908: 907: 904: 903: 881: 880: 874: 871: 870: 860: 859: 853: 849: 848: 845: 844: 822: 821: 815: 812: 811: 801: 800: 794: 790: 789: 786: 785: 777: 776: 770: 767: 766: 758: 757: 751: 745: 744: 741: 740: 732: 731: 725: 722: 721: 713: 712: 706: 700: 699: 696: 695: 687: 686: 680: 677: 676: 668: 667: 661: 655: 654: 649: 644: 640: 639: 629: 628: 625: 624: 613: 612: 610: 609: 604: 599: 593: 591: 587: 586: 584: 583: 578: 573: 568: 563: 561:nuclear matrix 558: 552: 550: 546: 545: 543: 542: 537: 531: 529: 525: 524: 514: 513: 510: 509: 506: 505: 497: 496: 485: 479: 478: 475: 474: 466: 465: 462: 461: 459: 458: 454: 450: 446: 442: 438: 434: 430: 426: 425:lacrimal gland 422: 418: 415: 414: 403: 400: 399: 397: 396: 392: 388: 384: 380: 376: 372: 368: 364: 360: 356: 353: 352: 340: 339: 331: 320: 314: 313: 310:RNA expression 302: 301: 298: 297: 289: 285: 284: 276: 273: 268: 262: 261: 252: 245: 239: 235: 234: 229: 223: 222: 214: 213: 201: 200: 197: 196: 188: 184: 183: 175: 172: 167: 161: 160: 151: 144: 138: 134: 133: 126: 120: 119: 111: 110: 98: 97: 54: 50: 49: 41: 33: 32: 28: 27: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 1642: 1631: 1628: 1626: 1623: 1622: 1620: 1609: 1604: 1602: 1597: 1595: 1590: 1589: 1583: 1581: 1577: 1573: 1572:chromosome 12 1569: 1564: 1561: 1557: 1552: 1544: 1540: 1535: 1530: 1526: 1522: 1518: 1513: 1509: 1505: 1500: 1495: 1491: 1487: 1483: 1478: 1474: 1470: 1465: 1460: 1456: 1452: 1448: 1444: 1440: 1435: 1431: 1427: 1422: 1417: 1412: 1407: 1403: 1399: 1395: 1391: 1387: 1382: 1378: 1374: 1369: 1364: 1360: 1356: 1352: 1348: 1344: 1339: 1335: 1331: 1326: 1321: 1316: 1311: 1307: 1303: 1302:J. Biol. Chem 1299: 1294: 1290: 1286: 1281: 1276: 1272: 1268: 1265:(1): 107–15. 1264: 1260: 1256: 1251: 1247: 1243: 1238: 1233: 1229: 1225: 1221: 1217: 1213: 1208: 1207: 1202: 1193: 1187: 1185: 1181: 1176: 1172: 1168: 1164: 1159: 1154: 1151:(6): 305–14. 1150: 1146: 1142: 1135: 1132: 1127: 1123: 1118: 1113: 1110:(3): 359–69. 1109: 1105: 1101: 1094: 1091: 1086: 1082: 1076: 1073: 1068: 1064: 1058: 1055: 1051: 1047: 1042: 1040: 1038: 1034: 1030: 1026: 1021: 1019: 1017: 1013: 1006: 1004: 1002: 998: 994: 989: 987: 984: 980: 976: 964: 959: 955: 951: 948: 944: 937: 935: 932: 928: 924: 920: 917: 913: 909: 902: 900: 896: 892: 888: 882: 878: 875: 869: 867: 861: 857: 854: 850: 843: 841: 837: 833: 829: 823: 819: 816: 810: 808: 802: 798: 795: 793:RefSeq (mRNA) 791: 784: 783: 778: 774: 771: 765: 764: 759: 755: 752: 750: 746: 739: 738: 733: 729: 726: 720: 719: 714: 710: 707: 705: 701: 694: 693: 688: 684: 681: 675: 674: 669: 665: 662: 660: 656: 653: 650: 648: 645: 641: 638: 634: 630: 623: 619: 614: 608: 605: 603: 600: 598: 595: 594: 592: 589: 588: 582: 579: 577: 574: 572: 569: 567: 564: 562: 559: 557: 554: 553: 551: 548: 547: 541: 538: 536: 533: 532: 530: 527: 526: 523: 522:Gene ontology 519: 515: 503: 498: 494: 489: 486: 484: 480: 472: 467: 456: 452: 449:hair follicle 448: 445:parotid gland 444: 440: 436: 432: 428: 424: 420: 419: 416: 412: 407: 404: 394: 390: 386: 382: 378: 374: 370: 366: 362: 358: 357: 354: 350: 345: 342: 341: 338: 336: 332: 330: 329: 325: 324: 321: 319: 315: 311: 307: 303: 295: 290: 286: 282: 277: 271:10|10 D2 267: 263: 256: 249: 243: 236: 228: 224: 220: 215: 211: 206: 202: 194: 189: 185: 181: 176: 166: 162: 155: 148: 142: 135: 131: 125: 121: 117: 112: 108: 103: 99: 95: 91: 87: 83: 79: 75: 71: 67: 63: 59: 51: 46: 39: 34: 29: 25: 20: 1580:expanding it 1565: 1550: 1527:(4): 145–9. 1524: 1520: 1492:(2): 89–92. 1489: 1485: 1446: 1442: 1393: 1389: 1350: 1346: 1305: 1301: 1262: 1258: 1219: 1215: 1148: 1144: 1134: 1107: 1103: 1093: 1084: 1075: 1066: 1057: 990: 982: 974: 973: 899:NP_001387974 895:NP_001387973 891:NP_001346547 887:NP_001074525 884: 863: 840:NM_001401045 836:NM_001401044 832:NM_001359618 828:NM_001081056 825: 804: 780: 761: 735: 716: 690: 671: 651: 646: 566:nuclear pore 535:tRNA binding 333: 326: 292:121,462,237 279:121,423,285 53:External IDs 1486:Biomed. Res 576:nucleoplasm 540:RNA binding 191:64,451,125 178:64,404,392 31:Identifiers 1619:Categories 1443:Genome Res 1259:Biochem. J 1052:, May 2017 1031:, May 2017 1007:References 993:RAN-GTPase 975:Exportin-T 337:(ortholog) 74:HomoloGene 1570:on human 1145:Curr Biol 866:NP_009166 807:NM_007235 637:Orthologs 556:cytoplasm 82:GeneCards 1543:17224653 1521:RNA Biol 1508:16707848 1473:15489334 1430:12477932 1377:12138183 1334:11024021 1289:10657246 1175:17803674 1104:Mol Cell 1048:– 1027:– 1001:exportin 947:Wikidata 616:Sources: 429:calvaria 1398:Bibcode 1280:1220829 1246:9857198 1237:1171087 1167:9512417 1126:9660920 1050:Ensembl 1029:Ensembl 979:protein 749:UniProt 704:Ensembl 643:Species 622:QuickGO 581:cytosol 571:nucleus 441:condyle 312:pattern 170:12q14.2 70:1920442 38:Aliases 1541:  1506:  1471:  1464:528928 1461:  1428:  1421:139241 1418:  1375:  1368:133969 1365:  1332:  1287:  1277:  1244:  1234:  1216:EMBO J 1173:  1165:  1124:  933:search 931:PubMed 782:Q9CRT8 763:O43592 659:Entrez 483:BioGPS 421:ureter 62:603180 1574:is a 1171:S2CID 977:is a 692:73192 673:11260 652:Mouse 647:Human 618:Amigo 437:fossa 335:Mouse 328:Human 275:Start 210:Mouse 174:Start 107:Human 78:38291 1576:stub 1568:gene 1539:PMID 1504:PMID 1469:PMID 1426:PMID 1373:PMID 1330:PMID 1285:PMID 1242:PMID 1163:PMID 1122:PMID 997:tRNA 986:gene 983:XPOT 318:Bgee 266:Band 227:Chr. 165:Band 124:Chr. 86:XPOT 58:OMIM 45:XPOT 22:XPOT 1529:doi 1494:doi 1459:PMC 1451:doi 1416:PMC 1406:doi 1363:PMC 1355:doi 1320:hdl 1310:doi 1306:275 1275:PMC 1267:doi 1263:346 1232:PMC 1224:doi 1153:doi 1112:doi 288:End 187:End 90:OMA 66:MGI 1621:: 1537:. 1523:. 1519:. 1502:. 1490:27 1488:. 1484:. 1467:. 1457:. 1447:14 1445:. 1441:. 1424:. 1414:. 1404:. 1394:99 1392:. 1388:. 1371:. 1361:. 1351:22 1349:. 1345:. 1328:. 1318:. 1304:. 1300:. 1283:. 1273:. 1261:. 1257:. 1240:. 1230:. 1220:17 1218:. 1214:. 1183:^ 1169:. 1161:. 1147:. 1143:. 1120:. 1106:. 1102:. 1083:. 1065:. 1036:^ 1015:^ 988:. 620:/ 294:bp 281:bp 193:bp 180:bp 88:; 84:: 80:; 76:: 72:; 68:: 64:; 60:: 1607:e 1600:t 1593:v 1582:. 1545:. 1531:: 1525:3 1510:. 1496:: 1475:. 1453:: 1432:. 1408:: 1400:: 1379:. 1357:: 1336:. 1322:: 1312:: 1291:. 1269:: 1248:. 1226:: 1194:. 1177:. 1155:: 1149:8 1128:. 1114:: 1108:1 1087:. 1069:. 212:) 109:) 92::

Index

Aliases
XPOT
OMIM
603180
MGI
1920442
HomoloGene
38291
GeneCards
XPOT
OMA
XPOT - orthologs
Human
Chromosome 12 (human)
Chr.
Chromosome 12 (human)
Chromosome 12 (human)
Genomic location for XPOT
Genomic location for XPOT
Band
bp
bp
Mouse
Chromosome 10 (mouse)
Chr.
Chromosome 10 (mouse)
Genomic location for XPOT
Genomic location for XPOT
Band
bp

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