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Xanthoma

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is clinically characterized by yellowish plaques that involve the palms and flexural surfaces of the fingers. Plane xanthomas are characterised by yellowish to orange, flat macules or slightly elevated plaques, often with a central white area which may be localised or generalised. They often arise in
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the skin folds, especially the palmar creases. They occur in hyperlipoproteinaemia type III and type IIA, and in association with biliary cirrhosis. The presence of palmar xanthomata, like the presence of tendinous xanthomata, is indicative of hypercholesterolaemia.
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E78.210) is clinically characterized by red papules and nodules that appear inflamed and tend to coalesce. Tuberous xanthomata are considered similar, and within the same disease spectrum as eruptive xanthomata.
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halo that appear suddenly all over the body, especially the hands, buttocks, and the extensor surfaces of the extremities. It tends to be associated with elevated triglycerides.
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The term xanthoma stems from Greek ξανθός (xanthós) 'yellow', and -ωμα -oma, a suffix forming nouns indicating a mass or tumor.
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Histology picture of xanthoma showing lipid-laden foam cells with large areas of cholesterol clefts, 10 Ă— magnification,
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Citing: The American Heritage Medical Dictionary Copyright 2007, 2004 and Mosby's Medical Dictionary, 8th edition. 2009
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is a sharply demarcated yellowish collection of cholesterol underneath the skin, usually on or around the
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D76.370), also known as plane xanthoma, is clinically characterized by bands or rectangular plates (
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van den Bosch HC, Vos LD (May 1998). "Achilles'-Tendon Xanthoma in Familial Hypercholesterolemia".
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Kumar AA, Shantha GP, Srinivasan Y, Senthil N, Rajkumar K, Paunikar N, Sudhakar M (August 2008).
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and nodules found in the tendons of the hands, feet, and heel. Also associated with
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E78.220) is clinically characterized by small, yellowish-orange to reddish-brown
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List of xanthoma variants associated with hyperlipoproteinemia subtypes
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Other types of xanthoma identified in the Medical Dictionary include:
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and skin whereby the connective tissue under the epithelium contains
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Tendon xanthomas are associated with type II hyperlipidemia, chronic
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Medical Dictionary - Dictionary of Medicine and Human Biology
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Eyelid, conjunctival, and orbital tumors: atlas and textbook
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Skin conditions resulting from errors in metabolism
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Andrews' Diseases of the Skin: clinical Dermatology
63: 41: 571:Digby M, Belli R, McGraw T, Lee A (January 2011). 823:Diseases of the skin and appendages by morphology 577:The Journal of Clinical and Aesthetic Dermatology 305:: a type of eruptive xanthoma, often with severe 446:James WD, Berger TG, Elston DM, Odom RB (2006). 1997:Lecithin cholesterol acyltransferase deficiency 319:on flexural (folded) surfaces, associated with 1889: 1308:Pityriasis lichenoides et varioliformis acuta 808: 8: 962:Dermatofibroma (benign fibrous histiocytoma) 511:Rapini RP, Bolognia JL, Jorizzo JL (2007). 375: 373: 27:Deposit of cholesterol within bodily tissue 1984: 1943:Familial apoprotein CII deficiency/Type Ib 1896: 1882: 1874: 1685: 1583: 1455: 1444: 1437: 1041: 1030: 832: 815: 801: 793: 638: 506: 504: 121:within the skin. They are associated with 78: 47: 38: 588: 441: 439: 437: 435: 433: 431: 429: 427: 407: 397: 1958:Familial dysbetalipoproteinemia/Type III 369: 1948:Familial hypercholesterolemia/Type IIa 1615:Disseminated intravascular coagulation 515:. St. Louis: Mosby. pp. 1415–16. 496:thefreedictionary.com > xanthelasma 1963:Familial hypertriglyceridemia/Type IV 1938:Lipoprotein lipase deficiency/Type Ia 7: 125:, both primary and secondary types. 538:The New England Journal of Medicine 1397:Postinflammatory hyperpigmentation 56:A patient's knee showing multiple 25: 1298:Transient acantholytic dermatosis 2083:APOA1 familial renal amyloidosis 1953:Combined hyperlipidemia/Type IIb 1407:Idiopathic guttate hypomelanosis 769: 315:: a rare xanthoma consisting of 1417:Hypopigmented mycosis fungoides 142:cerebrotendineous xanthomatosis 140:and the rare metabolic disease 105:) is a deposition of yellowish 1658:Lichen sclerosis et atrophicus 1366:Subcorneal pustular dermatosis 992:Infantile digital fibromatosis 1: 2030:Chylomicron retention disease 1250:Epidermolysis bullosa simplex 1087:Langerhans cell histiocytosis 471:Shields C, Shields J (2008). 218:familial hypercholesterolemia 1989:Hypoalphalipoproteinemia/HDL 1726:Systemic lupus erythematosus 1481:Systemic lupus erythematosus 1172:Systemic lupus erythematosus 2025:Apolipoprotein B deficiency 2012:Hypobetalipoproteinemia/LDL 1007:Lymphangioma circumscriptum 550:10.1056/NEJM199805283382205 177:eosin and hematoxylin stain 2130: 1829:Mucous membrane pemphigoid 164: 29: 2052:Barraquer–Simons syndrome 513:Dermatology: 2-Volume Set 134:primary biliary cirrhosis 130:biliary tract obstruction 55: 46: 1594:Thrombocytopenic purpura 1240:Dermatitis herpetiformis 1225:Acute contact dermatitis 1177:Pityriasis rubra pilaris 1102:Wiskott–Aldrich syndrome 1072:Lichen simplex chronicus 952:Epidermal inclusion cyst 783:MedlinePlus Encyclopedia 1859:Squamous-cell carcinoma 1854:Systemic histoplasmosis 1245:Porphyria cutanea tarda 875:Squamous-cell carcinoma 326:Verrucous xanthoma, or 283:Tuberoeruptive xanthoma 278:Tuberoeruptive xanthoma 1970:Xanthoma/Xanthomatosis 1834:Cicatricial pemphigoid 1751:Acne keloidalis nuchae 1746:Folliculitis decalvans 399:10.1186/1757-1626-1-71 179: 1736:Loose anagen syndrome 1663:Necrobiosis lipoidica 1599:Actinic/solar purpura 1273:Insect bite reactions 1062:Seborrheic dermatitis 885:Merkel-cell carcinoma 865:Molluscum contagiosum 450:. Saunders Elsevier. 313:Xanthoma disseminatum 303:Xanthoma diabeticorum 174: 2020:Abetalipoproteinemia 1933:Hypertriglyceridemia 1929:Hypercholesterolemia 1559:Annulare centrifugum 1082:Glucagonoma syndrome 880:Basal-cell carcinoma 855:Seborrheic keratosis 778:at Wikimedia Commons 117:accumulate in large 1980:Hypolipoproteinemia 1804:Aphthous stomatitis 1741:Lichen planopilaris 1716:Androgenic alopecia 1522:Fixed drug eruption 1097:Pemphigus foliaceus 997:Granular cell tumor 210:Xanthoma tendinosum 205:Xanthoma tendinosum 2078:Lipoid proteinosis 1824:Pemphigus vulgaris 1653:Granuloma annulare 1517:Carcinoid syndrome 1402:Tuberous sclerosis 1361:Coccidioidomycosis 1235:Bullous pemphigoid 1230:Pemphigus vulgaris 1162:Secondary syphilis 1052:Contact dermatitis 731:External resources 321:diabetes insipidus 199:Xanthoma tuberosum 194:Xanthoma tuberosum 180: 58:xanthoma tuberosum 2091: 2090: 2073:Adiposis dolorosa 2038: 2037: 1871: 1870: 1867: 1866: 1711:Telogen effluvium 1675: 1674: 1671: 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Index

Xanthoma planum
Xanthelasma

xanthoma tuberosum
Specialty
Gastroenterology
dermatology
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cholesterol
lipidosis
lipids
foam cells
hyperlipidemias
biliary tract obstruction
primary biliary cirrhosis
sitosterolemia
cerebrotendineous xanthomatosis
Xanthelasma

eosin and hematoxylin stain
xanthelasma
eyelids
papules
familial hypercholesterolemia
ILDS
papules
erythematous
ILDS
macules
ILDS

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