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for the newly created
Genetic Regulation Primary Focus, providing leadership for AAV pipeline advancement through commercialization, manufacturing expansion, and next-generation research initiatives. The acquisition includes Astellas gaining Xyphos’ Advanced Cellular Control through Engineered Ligands (ACCEL) technology platform.
594:
In
December 2019, Astellas Pharma announced it would buy Audentes Therapeutics Inc for approximately $ 3 billion in cash as well as acquiring Xyphos Biosciences, Inc later in the same month. Audentes will operate as a wholly owned subsidiary within Astellas, and will serve as the Center of Excellence
554:
for $ 4.0 billion. In
December 2014, Astellas expanded its 18-month-old collaboration with Cytokinetics, focusing on the R&D and commercialization of skeletal muscle activators. The companies announced they will advance the development of CK-2127107 (a fast skeletal troponin activator) into Phase
756:
In
December 2018, the Prescription Medicines Code of Practice Authority (PMCPA) published their findings following an allegation that Astellas had "inappropriately awarded research funding" to a senior clinician at a British hospital, directly resulting in the hospital adopting a protocol which was
530:
was established with the acquisition of the pharmaceutical division of Royal Gist
Brocades in 1991. Fujisawa and Yamanouchi combined in a "merger of equals," forming Astellas Pharma on 1 April 2005. At least some of its older products continue to be distributed under the original brand, ostensibly
752:
In June 2017, Astellas was reprimanded for "producing a large number of promotional materials, which had been used for a number of years, that did not include the required prescribing information related to some serious or common adverse reactions, warnings, and precautions, for a total of eight
1153:
In 2007, the company narrowed UK distribution of
Advagraf and Prograf to a sole distributor, UniChem, in reaction to pharmacist complaints about drug availability from wholesale sources. This narrow distribution was revised to three firms in 2010, covering all of its products in the UK: AAH,
575:
In March 2017, the company sold 16 of its drugs to LTL Pharma for ¥20.1 billion ($ 133 million). In April 2017, the company announced it would acquire
Belgium-based drug discovery firm Ogeda for up to a total €800 million, strengthening its late-stage pipeline with Ogeda's drug candidate,
542:
In 2009, the company's tacrolimus-containing products
Prograf and Advagraf showed they were prone to dosing errors within Europe, leading to serious adverse reactions among a number of patients, due to deficits in packaging and labeling, deficits corrected after a warning from the UK
620:
In May 2023, the business announced it would acquire Iveric Bio for $ 5.9 billion. In
November, Astellas announced it would acquire Propella Therapeutics, Inc. and its lead androgen biosynthesis inhibitor abiraterone decanoate (PRL-02) used to treat prostate cancer.
2364:
Manufacturers have, in the past, talked up the importance of bioequivalence to encourage prescribing of their brand.... Astellas is now conveniently ignoring that argument as it attempts to extend the life of Flomax beyond its patent expiry in
February
748:
In May 2017, the ABPI extended the suspension by a further 12 months, based on findings that Astellas was not adequately overseeing and training nurses, and that it had failed to provide complete prescribing information for several medicines.
745:(ABPI) gave Astellas a year-long suspension, after complaints it had "purposely misled the PMCPA." In particular, Astellas had not fully disclosed the nature of a meeting which had purported to be a "genuine advisory board".
616:
In October 2020, Astellas announced it would acquire iota Biosciences, Inc. for $ 127.5 million, with shareholders eligible to receive up to a further $ 176.5 million upon the achievement of predetermined milestones.
506:, and was renamed Fujisawa Pharmaceutical Co. in 1943. Yamanouchi Yakuhin Shokai was started in 1923 by Kenji Yamanouchi in Osaka. The company was renamed Yamanouchi Pharmaceutical Co. in 1940 and moved to
563:
conditions. The collaboration was expected to generate more than $ 600 million for Cytokinetics, as well as $ 75 million in milestone payments. In November 2015, the company announced its move to acquire
757:
subsequently abandoned less than three years later "because of poor outcomes". This report also reprimanded Astellas for failing to provide sufficient and timely information to investigators.
1194:, Netherlands. Combined revenues of the two pre-merger companies were $ 7.9 billion in 2004. Worldwide the company employs about 17,000 people. The United States subsidiary of Astellas is
4222:
568:(formerly Advanced Cell Technology) for $ 379 million. The deal was completed in February 2016. Later in November 2015 the company announced it would sell its dermatology business to
4252:
4232:
4237:
544:
591:
In August 2018, Astellas announced it would acquire Quethera Limited for $ 109 million. In December 2018, the company announced it would acquire Potenza Therapeutics, Inc.
742:
1141:. Zolbetuximab is the first treatment of its kind in the region, and a decision on its approval is expected by 12 January 2024, based on the Phase III SPOTLIGHT and GLOW
4262:
4227:
4247:
2155:"Two Pharmaceutical Companies Agree to Pay a Total of Nearly $ 125 Million to Resolve Allegations That They Paid Kickbacks Through Copay Assistance Foundations"
580:. In November 2017, the company announced that it exercised an option to purchase Cambridge, Massachusetts-based Mitobridge, which is developing treatments for
2154:
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The following is an illustration of the company's major mergers and acquisitions and historical predecessors (this is not a comprehensive list):
1587:
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due to high brand-name recognition. Astellas had a collaboration agreement with CoMentis from 2008 to 2014 focused on development of
1129:
The US Food and Drug Administration (FDA) has granted priority review to Astellas Pharma's biologics licence application (BLA) for
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2957:
2832:
1890:
1482:"Astellas Announces Results of Tender Offer to Acquire All Outstanding Shares of Ocata Therapeutics and Changes to Subsidiaries"
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482:
1987:
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1969:
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1940:
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581:
187:
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3376:
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3336:
2752:
2747:
1388:
1026:
3936:
3411:
3311:
3151:
2872:
2002:
1386:
Staff (November 15, 2014). "Astellas Ends Alzehimer's Collaboration with CoMentis". Discovery & Development.
935:
850:
844:
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for $ 725 million. In October 2016 Astellas announced it would acquire Ganymed Pharmaceuticals for $ 1.4 billion
434:
4242:
4202:
3018:
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1743:
1637:
809:
3611:
2827:
1821:
1710:
925:
Flomax MR capsules were discontinued in 2005, replaced by Flomaxtra XL, containing the same active ingredient
4176:
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556:
2792:
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1352:
3601:
3541:
3196:
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2536:
1356:
908:
823:
Recently noted, Astellas Venture Management has funded Oncorus, which recently raised $ 79.5 million in a
817:
536:
437:
125:
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3116:
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999:
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in 1942. Both companies started their overseas expansion at about the same time, opening offices in
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3011:
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2242:"Astellas Announces U.S. FDA Grants Priority Review for Zolbetuximab Biologics License Application"
1155:
662:
551:
523:
2304:
Slatko, Joshua (December 2013). "BMS changes senior management team". People on the Move: Pharma.
2022:
17:
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1614:"Astellas Acquires Mitobridge Under Existing Collaboration | Astellas Pharma Inc. GLOBAL WEBSITE"
1202:
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1097:
2362:(6520). Kent, England: CMP Information Ltd: 15. 12 November 2005 – via Internet Archive.
2216:(6513). Kent, England: CMP Information Ltd.: 12 24 September 2005 – via Internet Archive.
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On February 5, 2020, the company announced management changes effective from April 1, 2020.
344:
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1790:"Astellas Strengthens Immuno-oncology Pipeline with Acquisition of Xyphos Biosciences, Inc"
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2028:
1916:"Astellas' rheumatoid arthritis drug Smyraf wins regulatory nod – Korea Biomedical Review"
1662:"Astellas Expands Gene Therapy Investment, Acquires U.K.-based Quethera for $ 109 Million"
1481:
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1002:
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18.2 (CLDN18.2), for the treatment of HER2-negative gastric or gastroesophageal junction
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Fujisawa acquired Lyphomed in 1990 and thereafter established its US R&D center in
514:
in 1962 and 1963, respectively, and in the United States and Europe from 1977 onwards.
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2382:(6715). Kent, England: CMP Medica: 6. 12 September 2009 – via Internet Archive.
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2293:(6768). London, England: UBM Medica: 10. 9 October 2010 – via Internet Archive.
2282:
2270:
2205:
2181:"Cancer-killing virus boosts immuno-oncology responses in mice in Astellas-led study"
2107:"Astellas UK narrowly dodges expulsion after more trouble with Britain's pharma cops"
2091:
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1376:"Yamanouchi Pimafucin (natamycin) product line manufactured at least up to 11/2007"
1130:
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1055:
577:
1814:"Astellas ramps up M&A, buys U.S. biotech Xyphos for as much as $ 665 million"
1736:"Japan's Astellas to buy Audentes for $ 3 billion in high-priced gene therapy bet"
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1765:"Astellas Enters into Definitive Agreement to Acquire Audentes Therapeutics"
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2023:"Drugmaker Astellas sanctioned for 'shocking' patient safety failures"
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2060:"The whistleblowing drama behind Astellas's suspension from the ABPI"
1955:"Astellas to Buy Iveric Bio for $ 5.9B in Age-Related Blindness Play"
1191:
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978:
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511:
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1711:"Astellas Buys Audentes for $ 3 Billion to Expand into Gene Therapy"
1533:"Astellas to Acquire Ganymed Pharmaceuticals for Up to $ 1.4B – GEN"
764:$ 100 million to resolve allegations that it had conspired to offer
2228:"Astellas gains FDA priority review for gastric cancer therapy BLA"
613:, the third oral Janus kinase (JAK) inhibitor to receive approval.
4106:
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2267:(6622). Kent, England: CMP Medica: 7 – via Internet Archive.
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324:
231:
170:
107:
102:
2058:
Cohen, Deborah; Mulinari, Shai; Ozieranski, Piotr (2 July 2019).
1507:"LEO Pharma Buys Astellas' Dermatology Business for $ 725M – GEN"
849:
Adenoscan (adenosine injection) – Pharmacologic stress agent for
4036:
3906:
3416:
2877:
2606:
2526:
3007:
2441:
2003:"Astellas agrees to take over Propella Therapeutics for $ 175m"
1427:"Astellas, Cytokinetics Expand Muscle Drug Collaboration – GEN"
4146:
4011:
3626:
2269:. A news brief appears the following week in the publication—"
391:
191:
1867:"Astellas has announced its acquisition of Xyphos for $ 665m"
1588:"Astellas to Buy GPCR Drugs Firm Ogeda for up to €800M – GEN"
502:
Fujisawa Shoten was started in 1894 by Tomokichi Fujisawa in
2425:
30:"Astellas" redirects here. For similar sounding terms, see
1843:"Astellas Completes Acquisition of Audentes Therapeutics"
1456:"Astellas to Acquire Ocata Therapeutics for $ 379M – GEN"
827:
round to move two oncolytic viruses through development.
1277:"Astellas Pharma Financial Statements 2009-2024 | ALPMY"
835:
Some of the main products produced by Astellas include:
2133:"AUTH/2984/10/17 – Health Professional v Astellas UK"
609:) obtained regulatory approval for the treatment of
2640:
2479:
1970:"Astellas Pharma buys Iveric Bio for $ 5.9 billion"
387:
377:
362:
342:
322:
302:
282:
266:
209:
177:
161:
143:
131:
121:
82:
67:
2352:"One step ahead of manufacturers' tricky footwork"
2257:"Wholesale disbelief at Astellas sole supply deal"
2021:
743:Association of the British Pharmaceutical Industry
1450:
1448:
1392:(paper). Vol. 34, no. 20. p. 14.
1227:
471:
452:
426:
4223:Multinational companies headquartered in Japan
1559:"Transfer of 16 Long-Listed Products in Japan"
1221:
465:
446:
420:
3019:
2453:
1405:"MHRA warns of dosing errors in immune drugs"
8:
4253:Companies listed on the Tokyo Stock Exchange
4233:Pharmaceutical companies established in 2005
1638:"Astellas Announces Acquisition of Quethera"
1271:
1269:
1267:
1265:
1263:
1261:
1259:
934:injection) – Pharmacologic stress agent for
843:injection) – Pharmacologic stress agent for
440:, formed on 1 April 2005 from the merger of
53:
4238:Pharmaceutical companies of the Netherlands
2053:
2051:
1988:"Astellas to Acquire Propella Therapeutics"
3026:
3012:
3004:
2460:
2446:
2438:
2430:
760:In April 2019, Astellas agreed to pay the
52:
2322:"Corporate Philosophy of Astellas Pharma"
2255:Richardson, Jennifer (17 November 2007).
1891:"Astellas Announces Management Structure"
1687:"Astellas Acquires Potenza Therapeutics"
1415:(6686): 10 – via Internet Archive.
555:II clinical trials for the treatment of
4263:Companies based in Northbrook, Illinois
4228:Pharmaceutical companies based in Tokyo
2159:The United States Department of Justice
1255:
1158:, and Phoenix Healthcare Distribution.
473:Fujisawa Yakuhin Kōgyō Kabushiki-gaisha
4248:Japanese companies established in 2005
2036:from the original on December 11, 2022
1941:"Astellas to Acquire iota Biosciences"
1182:. Clinical development is centered in
7:
1403:Wilkinson, Emma (21 February 2009).
2001:Priyan, Vishnu (16 November 2023).
762:United States Department of Justice
550:On June 9, 2010, Astellas acquired
454:Yamanouchi Seiyaku Kabushiki-gaisha
442:Yamanouchi Pharmaceutical Co., Ltd.
1166:The company's headquarters are in
1133:, a monoclonal antibody targeting
428:Asuterasu Seiyaku Kabushiki-gaisha
25:
18:Yamanouchi Pharmaceutical Co., Ltd
4208:Pharmaceutical companies of Japan
2958:Sumitomo Realty & Development
2324:. Astellas Pharma. Archived from
2020:Megaw, Nicholas (June 23, 2017).
1326:. Astellas Pharma. Archived from
1297:. Astellas Pharma. Archived from
800:. Priority areas for R&D are
526:. Yamanouchi's R&D center in
461:Fujisawa Pharmaceutical Co., Ltd.
3035:
2408:
2394:
2105:Helfand, Carly (June 23, 2017).
768:via Medicare copay foundations.
411:Astellas Pharma office in Canada
369:
368:
351:
350:
331:
330:
311:
310:
291:
290:
271:
270:
59:
1011:ointment) – Atopic dermatitis (
399:Footnotes / references
27:Japanese pharmaceutical company
4218:Mitsubishi UFJ Financial Group
3727:Sompo Japan Nipponkoa Holdings
3307:Hitachi Construction Machinery
1871:European Pharmaceutical Review
776:Astellas' franchise areas are
483:Mitsubishi UFJ Financial Group
1:
977:(OAB) – US only; marketed by
656:Yamanouchi Pharmaceutical Co
1968:Swift, Rocky (May 1, 2023).
1820:. 2019-12-27. Archived from
1742:. 2019-12-03. Archived from
1109:AXL receptor tyrosine kinase
1068:(vasomotor symptoms) due to
920:Benign prostatic hyperplasia
481:Astellas is a member of the
4258:Companies in the Nikkei 225
3557:Mitsubishi Heavy Industries
2818:Mitsubishi Heavy Industries
1228:
708:Audentes Therapeutics Inc.
702:Potenza Therapeutics, Inc.
642:Fujisawa Pharmaceutical Co
639:Fujisawa Pharmaceutical Co
582:Duchenne muscular dystrophy
472:
453:
427:
4279:
1389:Gen. Eng. Biotechnol. News
1353:"Astellas Pharma Snapshot"
1027:Opioid replacement therapy
165:2-5-1, Nihonbashi-Honcho,
29:
3947:Sumitomo Mitsui Financial
3937:Sumitomo Heavy Industries
3052:
2612:Sumitomo Mitsui Financial
2372:"Ridaura Tiltab to cease"
2007:Pharmaceutical Technology
1222:
936:myocardial perfusion scan
851:myocardial perfusion scan
845:myocardial perfusion scan
810:gastrointestinal diseases
714:Xyphos Biosciences, Inc.
466:
447:
421:
397:
259:and other pharmaceuticals
135:Yamanouchi Pharmaceutical
58:
3782:Oji Holdings Corporation
2376:The Chemist and Druggist
2356:The Chemist and Druggist
2287:The Chemist and Druggist
2271:Astellas disappointment"
2261:The Chemist and Druggist
2210:The Chemist and Druggist
1409:The Chemist and Druggist
678:Ganymed Pharmaceuticals
533:beta-secretase inhibitor
518:Mergers and acquisitions
3682:Nippon Paper Industries
1922:(in Korean). 2020-01-30
1149:Distribution agreements
998:) – Prevention of post-
884:) – Prevention of post-
720:iota Biosciences, Inc.
557:spinal muscular atrophy
137:Fujisawa Pharmaceutical
103:TOPIX Core 30 Component
4213:Life sciences industry
3542:Mitsubishi Corporation
2582:Seven & i Holdings
2537:Mitsubishi Corporation
1357:Bloomberg Businessweek
1211:Leading Light for Life
909:chronic kidney disease
818:central nervous system
816:, and diseases of the
438:pharmaceutical company
412:
149:; 19 years ago
3957:Sumitomo Osaka Cement
3952:Sumitomo Mitsui Trust
3942:Sumitomo Metal Mining
3117:Bandai Namco Holdings
2953:Sumitomo Mitsui Trust
2948:Sumitomo Metal Mining
2688:Chugai Pharmaceutical
2673:Bandai Namco Holdings
410:
202:Chairman of the Board
4052:Tokuyama Corporation
3927:Sumitomo Corporation
3692:Nissan Motor Company
3622:Murata Manufacturing
3567:Mitsubishi Materials
3562:Mitsubishi Logistics
2938:Sumitomo Corporation
2733:Japan Exchange Group
2663:Asahi Group Holdings
1824:on December 27, 2019
1769:www.businesswire.com
1486:Newsroom.astellas.us
1321:"Annual Report 2014"
1244:Zeria Pharmaceutical
1217:Ashita wa kaerareru.
1188:La Jolla, California
1184:Northbrook, Illinois
611:rheumatoid arthritis
416:Astellas Pharma Inc.
392:www.astellas.com/en/
113:Nikkei 225 Component
54:Astellas Pharma Inc.
3547:Mitsubishi Electric
3537:Mitsubishi Chemical
3167:Concordia Financial
2893:Renesas Electronics
2808:Mitsubishi Electric
2803:Mitsubishi Chemical
2738:Japan Post Holdings
1990:. 15 November 2023.
1920:www.koreabiomed.com
1746:on December 3, 2019
1295:"Corporate Profile"
1203:advertising slogans
1156:Alliance Healthcare
1035:) – Non-small cell
802:infectious diseases
663:OSI Pharmaceuticals
625:Acquisition history
559:and possibly other
552:OSI Pharmaceuticals
537:Alzheimer's disease
524:Deerfield, Illinois
364:Number of employees
108:TOPIX 100 Component
55:
3912:Subaru Corporation
3672:Nippon Light Metal
3357:J. Front Retailing
2868:Ono Pharmaceutical
2328:on October 3, 2014
2032:. United Kingdom.
1943:. 15 October 2020.
1513:. 12 November 2015
1462:. 10 November 2015
1433:. 23 December 2014
1301:on August 14, 2012
1229:Changing Tomorrow.
1080:Overactive bladder
986:enfortumab vedotin
975:Overactive bladder
907:) - Anemia due to
825:series B financing
798:infectious disease
741:In June 2016, the
671:Ocata Therapeutics
601:Astellas Pharma's
566:Ocata Therapeutics
413:
373:14,484 (2023)
276:US$ 11.418 billion
4185:
4184:
4172:Yokogawa Electric
3932:Sumitomo Electric
3922:Sumitomo Chemical
3572:Mitsubishi Motors
3552:Mitsubishi Estate
3507:Matsui Securities
3487:Kyowa Hakko Kirin
3337:Isetan-Mitsukoshi
3292:Heiwa Real Estate
3282:Furukawa Electric
3272:Fukuoka Financial
3001:
3000:
2943:Sumitomo Electric
2813:Mitsubishi Estate
2471:100 companies of
2283:"Astellas Pharma"
2212:(News in brief).
2187:. 15 January 2020
2076:10.1136/bmj.l4353
1717:. 3 December 2019
1539:. 28 October 2016
1045:Hoffmann-La Roche
1041:pancreatic cancer
918:hydrochloride) –
729:
723:
717:
711:
705:
699:
696:Quethera Limited
693:
687:
681:
675:
667:
659:
651:
645:
535:therapeutics for
498:Early foundations
405:
404:
356:US$ 11.33 billion
336:US$ 18.47 billion
316:US$ 0.742 billion
205:
195:
147:1 April 2005
16:(Redirected from
4270:
4162:Yamato Transport
3832:Sapporo Holdings
3597:Mitsumi Electric
3582:Mitsui Chemicals
3197:Daiwa Securities
3157:Citizen Holdings
3040:
3039:
3038:
3028:
3021:
3014:
3005:
2462:
2455:
2448:
2439:
2434:
2429:
2428:
2426:Official website
2418:
2416:Companies portal
2413:
2412:
2411:
2404:
2399:
2398:
2397:
2383:
2367:
2338:
2337:
2335:
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2120:
2118:
2102:
2096:
2095:
2055:
2046:
2045:
2043:
2041:
2025:
2017:
2011:
2010:
1998:
1992:
1991:
1984:
1978:
1977:
1965:
1959:
1958:
1951:
1945:
1944:
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1931:
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1887:
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1839:
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1803:
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1786:
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1777:
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1761:
1755:
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1732:
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1723:
1722:
1707:
1701:
1700:
1698:
1697:
1683:
1677:
1676:
1674:
1673:
1668:. 10 August 2018
1658:
1652:
1651:
1649:
1648:
1634:
1628:
1627:
1625:
1624:
1610:
1604:
1603:
1601:
1599:
1584:
1578:
1577:
1575:
1573:
1563:
1555:
1549:
1548:
1546:
1544:
1529:
1523:
1522:
1520:
1518:
1503:
1497:
1496:
1494:
1492:
1478:
1472:
1471:
1469:
1467:
1452:
1443:
1442:
1440:
1438:
1423:
1417:
1416:
1400:
1394:
1393:
1383:
1377:
1374:
1368:
1367:
1365:
1363:
1349:
1343:
1342:
1340:
1338:
1333:on March 3, 2016
1332:
1325:
1317:
1311:
1310:
1308:
1306:
1291:
1285:
1284:
1273:
1233:
1231:
1225:
1224:
1121:– marketed with
1096:– marketed with
1094:lipoglycopeptide
1043:– marketed with
948:– marketed with
863:– marketed with
727:
721:
715:
709:
703:
697:
691:
685:
679:
673:
665:
657:
649:
643:
584:and age-related
477:
475:
469:
468:
458:
456:
450:
449:
432:
430:
424:
423:
372:
371:
357:
354:
353:
347:
337:
334:
333:
327:
317:
314:
313:
297:
294:
293:
285:Operating income
277:
274:
273:
199:
185:
157:
155:
150:
139:(Merged in 2005)
63:
56:
21:
4278:
4277:
4273:
4272:
4271:
4269:
4268:
4267:
4243:Japanese brands
4203:Astellas Pharma
4188:
4187:
4186:
4181:
4177:Yokohama Rubber
3982:Taiheiyo Cement
3967:Sumitomo Realty
3962:Sumitomo Pharma
3697:Nissan Chemical
3577:Mitsui & Co
3102:Asahi Breweries
3048:
3036:
3034:
3032:
3002:
2997:
2636:
2547:Mitsui & Co
2475:
2466:
2424:
2423:
2414:
2409:
2407:
2400:
2395:
2393:
2390:
2370:
2350:
2347:
2345:Further reading
2342:
2341:
2331:
2329:
2320:
2319:
2315:
2303:
2302:
2298:
2281:
2280:
2276:
2254:
2253:
2249:
2244:. July 6, 2023.
2240:
2239:
2235:
2230:. July 7, 2023.
2226:
2225:
2221:
2204:
2203:
2199:
2190:
2188:
2179:
2178:
2174:
2164:
2162:
2161:(Press release)
2153:
2152:
2148:
2138:
2136:
2131:
2130:
2126:
2116:
2114:
2113:. United States
2104:
2103:
2099:
2057:
2056:
2049:
2039:
2037:
2029:Financial Times
2019:
2018:
2014:
2000:
1999:
1995:
1986:
1985:
1981:
1967:
1966:
1962:
1953:
1952:
1948:
1939:
1938:
1934:
1925:
1923:
1914:
1913:
1909:
1900:
1898:
1897:. 12 March 2020
1889:
1888:
1884:
1875:
1873:
1865:
1864:
1860:
1851:
1849:
1841:
1840:
1836:
1827:
1825:
1812:
1811:
1807:
1798:
1796:
1788:
1787:
1783:
1774:
1772:
1763:
1762:
1758:
1749:
1747:
1734:
1733:
1729:
1720:
1718:
1709:
1708:
1704:
1695:
1693:
1685:
1684:
1680:
1671:
1669:
1660:
1659:
1655:
1646:
1644:
1636:
1635:
1631:
1622:
1620:
1612:
1611:
1607:
1597:
1595:
1586:
1585:
1581:
1571:
1569:
1568:. 28 March 2017
1561:
1557:
1556:
1552:
1542:
1540:
1531:
1530:
1526:
1516:
1514:
1505:
1504:
1500:
1490:
1488:
1480:
1479:
1475:
1465:
1463:
1454:
1453:
1446:
1436:
1434:
1425:
1424:
1420:
1402:
1401:
1397:
1385:
1384:
1380:
1375:
1371:
1361:
1359:
1351:
1350:
1346:
1336:
1334:
1330:
1323:
1319:
1318:
1314:
1304:
1302:
1293:
1292:
1288:
1275:
1274:
1257:
1252:
1240:
1219:
1196:Astellas US LLC
1164:
1151:
1119:Prostate cancer
1003:organ rejection
950:Gilead Sciences
946:Anti-angiogenic
889:organ rejection
865:Gilead Sciences
833:
790:transplantation
774:
739:
734:
635:Astellas Pharma
627:
520:
500:
495:
463:
444:
418:
401:
365:
355:
343:
335:
323:
315:
307:
295:
287:
275:
262:
198:
196:
184:
180:
173:103-8411, Japan
153:
151:
148:
138:
136:
117:
87:
51:
28:
23:
22:
15:
12:
11:
5:
4276:
4274:
4266:
4265:
4260:
4255:
4250:
4245:
4240:
4235:
4230:
4225:
4220:
4215:
4210:
4205:
4200:
4190:
4189:
4183:
4182:
4180:
4179:
4174:
4169:
4164:
4159:
4154:
4149:
4144:
4139:
4134:
4129:
4124:
4119:
4114:
4109:
4104:
4099:
4094:
4089:
4084:
4079:
4077:Tokyo Tatemono
4074:
4069:
4067:Tokyo Electron
4064:
4059:
4054:
4049:
4044:
4039:
4034:
4029:
4024:
4019:
4014:
4009:
4004:
3999:
3994:
3989:
3984:
3979:
3974:
3969:
3964:
3959:
3954:
3949:
3944:
3939:
3934:
3929:
3924:
3919:
3914:
3909:
3904:
3899:
3894:
3889:
3884:
3879:
3874:
3869:
3864:
3859:
3854:
3849:
3844:
3839:
3834:
3829:
3824:
3819:
3814:
3809:
3807:Pacific Metals
3804:
3799:
3794:
3789:
3784:
3779:
3774:
3769:
3764:
3759:
3754:
3749:
3744:
3739:
3734:
3729:
3724:
3719:
3714:
3709:
3704:
3702:Nisshin Seifun
3699:
3694:
3689:
3684:
3679:
3674:
3669:
3664:
3662:Nippon Express
3659:
3654:
3649:
3644:
3639:
3634:
3629:
3624:
3619:
3614:
3609:
3604:
3599:
3594:
3592:Mitsui Kinzoku
3589:
3587:Mitsui Fudosan
3584:
3579:
3574:
3569:
3564:
3559:
3554:
3549:
3544:
3539:
3534:
3529:
3524:
3522:Meiji Holdings
3519:
3514:
3509:
3504:
3499:
3497:Maruha Nichiro
3494:
3489:
3484:
3479:
3474:
3469:
3467:Konica Minolta
3464:
3459:
3454:
3449:
3444:
3439:
3434:
3429:
3424:
3419:
3414:
3409:
3404:
3399:
3394:
3389:
3384:
3379:
3374:
3369:
3364:
3359:
3354:
3349:
3344:
3339:
3334:
3329:
3324:
3319:
3317:Hokuetsu Paper
3314:
3309:
3304:
3299:
3294:
3289:
3284:
3279:
3277:Furukawa Group
3274:
3269:
3264:
3259:
3254:
3249:
3247:Fast Retailing
3244:
3239:
3234:
3229:
3224:
3219:
3214:
3209:
3204:
3199:
3194:
3189:
3184:
3182:Daiichi Sankyo
3179:
3174:
3169:
3164:
3159:
3154:
3149:
3144:
3139:
3134:
3129:
3124:
3119:
3114:
3109:
3104:
3099:
3094:
3089:
3084:
3079:
3074:
3069:
3064:
3059:
3053:
3050:
3049:
3033:
3031:
3030:
3023:
3016:
3008:
2999:
2998:
2996:
2995:
2990:
2985:
2980:
2975:
2970:
2965:
2960:
2955:
2950:
2945:
2940:
2935:
2930:
2928:Sompo Holdings
2925:
2920:
2915:
2910:
2905:
2900:
2895:
2890:
2885:
2880:
2875:
2870:
2865:
2860:
2855:
2850:
2845:
2840:
2835:
2830:
2825:
2823:Mitsui Fudosan
2820:
2815:
2810:
2805:
2800:
2795:
2790:
2785:
2780:
2775:
2770:
2765:
2760:
2755:
2750:
2745:
2740:
2735:
2730:
2725:
2720:
2718:Fast Retailing
2715:
2710:
2705:
2700:
2695:
2690:
2685:
2680:
2675:
2670:
2665:
2660:
2655:
2650:
2644:
2642:
2638:
2637:
2635:
2634:
2629:
2627:Tokyo Electron
2624:
2619:
2614:
2609:
2604:
2602:SoftBank Group
2599:
2594:
2589:
2584:
2579:
2574:
2569:
2564:
2559:
2554:
2549:
2544:
2539:
2534:
2529:
2524:
2519:
2514:
2509:
2504:
2499:
2494:
2492:Daiichi Sankyo
2489:
2483:
2481:
2477:
2476:
2467:
2465:
2464:
2457:
2450:
2442:
2436:
2435:
2420:
2419:
2405:
2389:
2388:External links
2386:
2385:
2384:
2378:(News brief).
2368:
2346:
2343:
2340:
2339:
2313:
2296:
2289:(News brief).
2274:
2247:
2233:
2219:
2197:
2185:Fierce Biotech
2172:
2146:
2124:
2097:
2047:
2012:
1993:
1979:
1960:
1946:
1932:
1907:
1882:
1858:
1834:
1805:
1781:
1756:
1727:
1702:
1678:
1653:
1629:
1605:
1594:. 3 April 2017
1579:
1550:
1524:
1498:
1473:
1444:
1418:
1395:
1378:
1369:
1344:
1312:
1286:
1254:
1253:
1251:
1248:
1247:
1246:
1239:
1236:
1235:
1234:
1213:
1201:The company's
1163:
1160:
1150:
1147:
1143:clinical trial
1139:adenocarcinoma
1127:
1126:
1111:
1101:
1083:
1072:
1058:
1048:
1029:
1016:
1005:
992:
990:Bladder cancer
982:
981:Outside of US.
967:
957:
956:Outside of US.
952:in the US and
938:
928:
927:
926:
912:
901:
891:
878:
868:
857:amphotericin B
853:
847:
832:
829:
773:
770:
738:
735:
733:
732:
731:
730:
724:
718:
712:
706:
700:
694:
688:
682:
676:
668:
660:
654:
653:
652:
646:
631:
626:
623:
519:
516:
499:
496:
494:
491:
433:is a Japanese
403:
402:
395:
394:
389:
385:
384:
381:
375:
374:
366:
363:
360:
359:
348:
340:
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328:
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308:
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263:
261:
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224:
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211:
207:
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197:Kenji Yasukawa
181:
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159:
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145:
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140:
133:
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126:Pharmaceutical
123:
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90:
88:
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69:
65:
64:
26:
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14:
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10:
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6:
4:
3:
2:
4275:
4264:
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4153:
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4135:
4133:
4130:
4128:
4127:Toyota Tsusho
4125:
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4120:
4118:
4115:
4113:
4110:
4108:
4105:
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4098:
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4018:
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4010:
4008:
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4000:
3998:
3995:
3993:
3990:
3988:
3985:
3983:
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3970:
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3910:
3908:
3905:
3903:
3900:
3898:
3895:
3893:
3890:
3888:
3885:
3883:
3882:Shizuoka Bank
3880:
3878:
3875:
3873:
3870:
3868:
3865:
3863:
3860:
3858:
3855:
3853:
3850:
3848:
3847:Sekisui House
3845:
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3825:
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3808:
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3733:
3730:
3728:
3725:
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3720:
3718:
3715:
3713:
3710:
3708:
3707:Nisshin Steel
3705:
3703:
3700:
3698:
3695:
3693:
3690:
3688:
3685:
3683:
3680:
3678:
3675:
3673:
3670:
3668:
3667:Nippon Kayaku
3665:
3663:
3660:
3658:
3655:
3653:
3650:
3648:
3645:
3643:
3640:
3638:
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3488:
3485:
3483:
3480:
3478:
3475:
3473:
3470:
3468:
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3330:
3328:
3325:
3323:
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3308:
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3300:
3298:
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3280:
3278:
3275:
3273:
3270:
3268:
3265:
3263:
3260:
3258:
3255:
3253:
3252:Fuji Electric
3250:
3248:
3245:
3243:
3240:
3238:
3235:
3233:
3230:
3228:
3225:
3223:
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3205:
3203:
3200:
3198:
3195:
3193:
3190:
3188:
3185:
3183:
3180:
3178:
3177:Dai-ichi Life
3175:
3173:
3172:Credit Saison
3170:
3168:
3165:
3163:
3160:
3158:
3155:
3153:
3150:
3148:
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3110:
3108:
3105:
3103:
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3098:
3095:
3093:
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3088:
3085:
3083:
3080:
3078:
3075:
3073:
3070:
3068:
3065:
3063:
3060:
3058:
3055:
3054:
3051:
3047:
3044:companies of
3043:
3029:
3024:
3022:
3017:
3015:
3010:
3009:
3006:
2994:
2991:
2989:
2986:
2984:
2981:
2979:
2976:
2974:
2971:
2969:
2966:
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2961:
2959:
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2936:
2934:
2931:
2929:
2926:
2924:
2921:
2919:
2916:
2914:
2911:
2909:
2908:Sekisui House
2906:
2904:
2901:
2899:
2896:
2894:
2891:
2889:
2886:
2884:
2881:
2879:
2876:
2874:
2873:Oriental Land
2871:
2869:
2866:
2864:
2861:
2859:
2856:
2854:
2851:
2849:
2846:
2844:
2841:
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2726:
2724:
2721:
2719:
2716:
2714:
2711:
2709:
2706:
2704:
2701:
2699:
2696:
2694:
2693:Dai-ichi Life
2691:
2689:
2686:
2684:
2681:
2679:
2676:
2674:
2671:
2669:
2666:
2664:
2661:
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2649:
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2523:
2520:
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2505:
2503:
2500:
2498:
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2392:
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2369:
2366:
2361:
2357:
2353:
2349:
2348:
2344:
2327:
2323:
2317:
2314:
2310:. p. 27.
2309:
2308:
2300:
2297:
2292:
2288:
2284:
2278:
2275:
2272:
2266:
2262:
2258:
2251:
2248:
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2237:
2234:
2229:
2223:
2220:
2215:
2211:
2207:
2201:
2198:
2186:
2182:
2176:
2173:
2160:
2156:
2150:
2147:
2134:
2128:
2125:
2112:
2108:
2101:
2098:
2093:
2089:
2085:
2081:
2077:
2073:
2069:
2065:
2061:
2054:
2052:
2048:
2035:
2031:
2030:
2024:
2016:
2013:
2008:
2004:
1997:
1994:
1989:
1983:
1980:
1975:
1971:
1964:
1961:
1956:
1950:
1947:
1942:
1936:
1933:
1921:
1917:
1911:
1908:
1896:
1892:
1886:
1883:
1872:
1868:
1862:
1859:
1848:
1844:
1838:
1835:
1823:
1819:
1815:
1809:
1806:
1795:
1791:
1785:
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1770:
1766:
1760:
1757:
1745:
1741:
1737:
1731:
1728:
1716:
1712:
1706:
1703:
1692:
1688:
1682:
1679:
1667:
1663:
1657:
1654:
1643:
1639:
1633:
1630:
1619:
1615:
1609:
1606:
1593:
1589:
1583:
1580:
1567:
1560:
1554:
1551:
1538:
1534:
1528:
1525:
1512:
1508:
1502:
1499:
1487:
1483:
1477:
1474:
1461:
1457:
1451:
1449:
1445:
1432:
1428:
1422:
1419:
1414:
1410:
1406:
1399:
1396:
1391:
1390:
1382:
1379:
1373:
1370:
1358:
1354:
1348:
1345:
1329:
1322:
1316:
1313:
1300:
1296:
1290:
1287:
1282:
1278:
1272:
1270:
1268:
1266:
1264:
1262:
1260:
1256:
1249:
1245:
1242:
1241:
1237:
1230:
1218:
1214:
1212:
1208:
1207:
1206:
1204:
1199:
1197:
1193:
1189:
1185:
1181:
1177:
1173:
1169:
1161:
1159:
1157:
1148:
1146:
1144:
1140:
1136:
1132:
1124:
1120:
1116:
1112:
1110:
1106:
1102:
1099:
1095:
1092:
1088:
1084:
1081:
1078:succinate) –
1077:
1073:
1071:
1067:
1063:
1059:
1057:
1053:
1049:
1046:
1042:
1038:
1034:
1030:
1028:
1024:
1021:
1017:
1014:
1010:
1006:
1004:
1001:
997:
993:
991:
987:
983:
980:
976:
972:
968:
966:
962:
958:
955:
951:
947:
943:
939:
937:
933:
929:
924:
923:
921:
917:
913:
910:
906:
902:
900:
896:
895:isavuconazole
892:
890:
887:
883:
880:Astagraf XL (
879:
877:
873:
869:
866:
862:
858:
854:
852:
848:
846:
842:
838:
837:
836:
830:
828:
826:
821:
819:
815:
811:
807:
803:
799:
795:
791:
787:
783:
779:
771:
769:
767:
763:
758:
754:
750:
746:
744:
737:Controversies
736:
725:
719:
713:
707:
701:
695:
689:
683:
677:
672:
669:
664:
661:
655:
647:
641:
640:
638:
637:
636:
633:
632:
630:
624:
622:
618:
614:
612:
608:
605:(ingredient:
604:
599:
596:
592:
589:
587:
583:
579:
573:
571:
567:
562:
561:neuromuscular
558:
553:
548:
546:
540:
538:
534:
529:
525:
517:
515:
513:
509:
505:
497:
492:
490:
488:
484:
479:
474:
462:
455:
443:
439:
436:
435:multinational
429:
417:
409:
400:
396:
393:
390:
386:
382:
380:
376:
367:
361:
349:
346:
341:
329:
326:
321:
309:
306:
301:
296:US$ 1 billion
289:
286:
281:
269:
265:
258:
255:
253:
250:
248:
245:
243:
240:
238:
235:
233:
230:
228:
225:
223:
220:
218:
215:
214:
212:
208:
203:
193:
189:
183:Naoki Okamura
182:
176:
172:
168:
164:
160:
146:
142:
134:
130:
127:
124:
120:
114:
111:
109:
106:
104:
101:
99:
95:
92:
91:
89:
86:
81:
77:
73:
70:
66:
62:
57:
49:
45:
41:
37:
33:
19:
4152:Yahoo! Japan
4057:Tokio Marine
4047:Tokai Carbon
3867:Shinsei Bank
3111:
2838:Nippon Yusen
2833:Nippon Steel
2622:Tokio Marine
2486:
2402:Japan portal
2379:
2375:
2363:
2359:
2355:
2332:September 9,
2330:. Retrieved
2326:the original
2316:
2305:
2299:
2290:
2286:
2277:
2264:
2260:
2250:
2236:
2222:
2213:
2209:
2200:
2189:. Retrieved
2184:
2175:
2163:. Retrieved
2158:
2149:
2137:. Retrieved
2127:
2115:. Retrieved
2111:FiercePharma
2110:
2100:
2067:
2063:
2038:. Retrieved
2027:
2015:
2006:
1996:
1982:
1973:
1963:
1949:
1935:
1924:. Retrieved
1919:
1910:
1899:. Retrieved
1895:BioPortfolio
1894:
1885:
1874:. Retrieved
1870:
1861:
1850:. Retrieved
1846:
1837:
1826:. Retrieved
1822:the original
1817:
1808:
1797:. Retrieved
1793:
1784:
1773:. Retrieved
1771:. 2019-12-02
1768:
1759:
1748:. Retrieved
1744:the original
1739:
1730:
1719:. Retrieved
1714:
1705:
1694:. Retrieved
1690:
1681:
1670:. Retrieved
1665:
1656:
1645:. Retrieved
1641:
1632:
1621:. Retrieved
1618:Astellas.com
1617:
1608:
1596:. Retrieved
1591:
1582:
1570:. Retrieved
1565:
1553:
1541:. Retrieved
1536:
1527:
1515:. Retrieved
1510:
1501:
1489:. Retrieved
1485:
1476:
1464:. Retrieved
1459:
1435:. Retrieved
1430:
1421:
1412:
1408:
1398:
1387:
1381:
1372:
1360:. Retrieved
1347:
1337:September 9,
1335:. Retrieved
1328:the original
1315:
1305:September 9,
1303:. Retrieved
1299:the original
1289:
1280:
1216:
1210:
1200:
1195:
1165:
1152:
1131:Zolbetuximab
1128:
1115:enzalutamide
1105:gilteritinib
1091:bactericidal
1062:fezolinetant
1056:Hyponatremia
1047:(Genentech).
834:
822:
775:
759:
755:
751:
747:
740:
634:
628:
619:
615:
600:
597:
593:
590:
578:fezolinetant
574:
549:
541:
521:
501:
480:
460:
441:
415:
414:
398:
379:Subsidiaries
358: (2023)
345:Total equity
338: (2023)
325:Total assets
318: (2023)
298: (2023)
278: (2023)
162:Headquarters
132:Predecessors
68:Company type
4132:Trend Micro
4002:Takashimaya
3992:Taiyo Yuden
3892:Showa Shell
3887:Showa Denko
3722:Nitto Denko
3687:Nippon Soda
3192:Daiwa House
3122:Bridgestone
3107:Asahi Kasei
3097:Aozora Bank
2698:Daiwa House
2678:Bridgestone
2668:Asahi Kasei
2358:(Opinion).
2307:Med Ad News
2206:"Flomax MR"
1957:. May 2023.
1362:January 25,
1281:macrotrends
1174:centers in
1076:solifenacin
1066:Hot Flashes
1037:lung cancer
969:Myrbetriq (
965:Anti-fungal
932:regadenoson
899:Anti-fungal
874:) – plaque
861:Anti-fungal
839:Adenocard (
726:Iveric Bio
690:Mitobridge
607:peficitinib
422:アステラス製薬株式会社
383:Astellas US
4192:Categories
4087:Tokyu Land
4062:Tokyo Dome
3677:Nippon Ham
3367:JR Central
3137:Chiba Bank
3042:Nikkei 225
2993:Z Holdings
2743:JR Central
2607:Sony Group
2191:2020-03-13
1926:2020-03-26
1901:2020-04-02
1876:2020-02-25
1852:2020-03-04
1828:2020-04-21
1799:2020-04-21
1775:2019-12-16
1750:2020-04-21
1721:2020-04-21
1696:2020-04-21
1672:2020-04-21
1647:2020-04-21
1623:2018-02-27
1572:3 November
1250:References
1215:Japanese:
1162:Operations
1098:Theravance
1087:telavancin
1074:Vesicare (
1052:conivaptan
1050:Vaprisol (
1009:tacrolimus
1007:Protopic (
1000:transplant
996:tacrolimus
971:mirabegron
963:sodium) –
961:micafungin
959:Mycamine (
944:sodium) –
942:pegaptanib
930:Lexiscan (
916:tamsulosin
905:roxadustat
893:Cresemba (
886:transplant
882:tacrolimus
855:AmBisome (
794:cardiology
786:immunology
728:(Acq 2023)
722:(Acq 2020)
716:(Acq 2019)
710:(Acq 2019)
704:(Acq 2018)
698:(Acq 2018)
692:(Acq 2017)
686:(Acq 2017)
680:(Acq 2016)
674:(Acq 2016)
666:(Acq 2010)
658:(Est 1923)
650:(Acq 1990)
644:(Est 1894)
570:LEO Pharma
528:Leiderdorp
467:藤沢薬品工業株式会社
305:Net income
179:Key people
154:2005-04-01
4198:TOPIX 100
4072:Tokyo Gas
4042:Toho Zinc
3862:Shin-Etsu
3812:Panasonic
3802:Osaka Gas
3612:MS&AD
3517:Meidensha
3077:Ajinomoto
3062:Advantest
2888:Panasonic
2828:MS&AD
2653:Ajinomoto
2587:Shin-Etsu
2092:195788432
2070:: l4353.
1598:13 August
1543:13 August
1517:13 August
1491:13 August
1466:13 August
1437:13 August
1223:明日は変えられる。
1209:English:
1145:results.
1103:Xospata (
1085:Vibativ (
1070:menopause
1033:erlotinib
1031:Tarceva (
1020:methadone
1018:Symoron (
994:Prograf (
940:Macugen (
903:Evrenzo (
876:psoriasis
872:alefacept
870:Amevive (
841:adenosine
766:kickbacks
648:Lyphomed
448:山之内製薬株式会社
188:President
85:Traded as
4167:Yasakawa
3897:SoftBank
3877:Shiseido
3872:Shionogi
3772:Obayashi
3762:NTT Data
3657:Nintendo
3647:Nichirei
3492:Marubeni
3437:Kikkoman
3412:Kawasaki
3287:GS Yuasa
3262:Fujikura
3257:Fujifilm
3112:Astellas
2988:Unicharm
2923:Shiseido
2918:Shionogi
2798:Marubeni
2788:Lasertec
2723:Fujifilm
2641:Large 70
2597:SoftBank
2567:Nintendo
2487:Astellas
2084:31266743
2040:June 23,
2034:Archived
1847:BioSpace
1794:BioSpace
1715:BioSpace
1691:BioSpace
1666:BioSpace
1642:BioSpace
1566:Astellas
1238:See also
1172:research
1113:Xtandi (
1060:Veozah (
984:Padcev (
914:Flomax (
831:Products
814:oncology
806:diabetes
778:oncology
772:Business
753:drugs".
586:diseases
487:keiretsu
210:Products
122:Industry
36:Astellia
4142:Unitika
4102:Toshiba
3977:T&D
3817:Pioneer
3797:Olympus
3717:Nittobo
3532:Minebea
3482:Kyocera
3477:Kuraray
3457:Komatsu
3452:Kobelco
3432:Keyence
3377:JR West
3372:JR East
3302:Hitachi
3267:Fujitsu
3142:Chiyoda
3057:7&i
2983:Toshiba
2913:Shimano
2858:Olympus
2783:Kyocera
2773:Komatsu
2753:JR West
2748:JR East
2728:Fujitsu
2577:Recruit
2532:Keyence
2507:Hitachi
2480:Core 30
2135:. PMCPA
2117:July 3,
1974:Reuters
1818:Reuters
1740:Reuters
1176:Tsukuba
1170:, with
1135:Claudin
782:urology
493:History
485:(MUFJ)
388:Website
267:Revenue
257:Prograf
252:Betanis
247:Evrenzo
242:Izervay
227:Xospata
167:Chūō-ku
152: (
144:Founded
44:Astelma
32:Astelia
4157:Yamaha
4122:Toyota
4117:Toyobo
4092:Toppan
4027:Terumo
4017:Teijin
4007:Takeda
3997:Takara
3987:Taisei
3972:Suzuki
3902:Sojitz
3837:SCREEN
3822:Resona
3777:Odakyu
3732:Nomura
3712:Nissui
3602:Mizuho
3472:Kubota
3462:Konami
3447:K Line
3427:Keisei
3397:Kajima
3347:Itochu
3212:Dentsu
3187:Daikin
3162:Comsys
3152:Chugai
3147:Chuden
2973:Terumo
2968:Sysmex
2963:Suzuki
2933:Subaru
2898:Resona
2883:Otsuka
2853:Nomura
2848:Nitori
2843:Nissan
2793:M3.com
2778:Kubota
2632:Toyota
2617:Takeda
2557:Murata
2552:Mizuho
2522:Itochu
2497:Daikin
2165:3 July
2139:3 July
2090:
2082:
1192:Leiden
1190:, and
1123:Pfizer
1013:eczema
979:Pfizer
954:Pfizer
922:(BPH)
796:, and
684:Ogeda
603:Smyraf
512:Taiwan
237:Veozah
222:Padcev
217:Xtandi
72:Public
48:Astala
46:, and
40:Astell
4107:Tosoh
4097:Toray
4082:Tokyu
4022:TEPCO
3917:SUMCO
3857:Shimz
3852:Sharp
3842:Secom
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