242:
219:
116:
141:
248:
147:
1214:
255:
154:
698:
717:
77:
1283:
1107:
1259:
1125:
1278:
953:
241:
960:
218:
1094:
1073:
1090:
140:
115:
1069:
57:
254:
153:
247:
146:
1252:
762:
65:
743:
1042:
1245:
129:
44:
936:
932:
928:
907:
899:
873:
869:
865:
844:
840:
832:
89:
903:
836:
1176:
37:
1229:
1145:"PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease"
1166:
1156:
334:
265:
209:
164:
85:
309:
1171:
1144:
632:
627:
622:
617:
612:
607:
591:
586:
581:
565:
560:
555:
550:
545:
540:
535:
530:
525:
1272:
512:
69:
1225:
327:
106:
93:
1130:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1112:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1024:
1161:
1143:
Shin JH, Ko HS, Kang H, Lee Y, Lee YI, Pletinkova O, et al. (March 2011).
410:
1195:"Entrez Gene: ZNF746 zinc finger protein 746 [ Homo sapiens (human) ]"
226:
123:
73:
662:
470:
348:
293:
280:
192:
179:
81:
1194:
1180:
1000:
995:
984:
807:
788:
541:
DNA-binding transcription repressor activity, RNA polymerase II-specific
1027:
774:
729:
968:
684:
566:
DNA-binding transcription factor activity, RNA polymerase II-specific
531:
RNA polymerase II cis-regulatory region sequence-specific DNA binding
1213:
1031:
647:
643:
1221:
1038:
61:
633:
positive regulation of transcription by RNA polymerase II
618:
negative regulation of transcription by RNA polymerase II
317:
1233:
482:
921:
892:
858:
825:
608:
negative regulation of transcription, DNA-templated
1086:
1084:
1082:
1065:
1063:
1061:
264:
163:
16:Protein-coding gene in the species Homo sapiens
1091:GRCm38: Ensembl release 89: ENSMUSG00000057691
1253:
8:
1041:and is involved in the neurodegeneration of
1070:GRCh38: Ensembl release 89: ENSG00000181220
48:, P.A.R.I.S, PARIS, zinc finger protein 746
1260:
1246:
658:
623:regulation of transcription, DNA-templated
508:
305:
204:
101:
1170:
1160:
526:DNA-binding transcription factor activity
1057:
18:
269:
230:
225:
168:
127:
122:
7:
1210:
1208:
613:positive regulation of neuron death
1232:. You can help Knowledge (XXG) by
918:
889:
855:
822:
798:
779:
753:
734:
708:
689:
587:intracellular anatomical structure
487:
405:
343:
322:
14:
1212:
551:ubiquitin protein ligase binding
253:
246:
240:
217:
152:
145:
139:
114:
471:More reference expression data
1:
1284:Human chromosome 7 gene stubs
238:
137:
1017:Parkin-interacting substrate
628:transcription, DNA-templated
1279:Genes on human chromosome 7
387:stromal cell of endometrium
1300:
1207:
1162:10.1016/j.cell.2011.02.010
1126:"Mouse PubMed Reference:"
1108:"Human PubMed Reference:"
999:
994:
990:
983:
967:
948:
925:
896:
885:
862:
829:
818:
805:
801:
786:
782:
773:
760:
756:
741:
737:
728:
715:
711:
696:
692:
683:
668:
661:
657:
641:
511:
507:
495:
490:
481:
468:
417:
408:
355:
346:
316:
308:
304:
287:
274:
237:
216:
207:
203:
186:
173:
136:
113:
104:
100:
55:
52:
42:
35:
30:
26:
21:
954:Chr 7: 149.47 – 149.5 Mb
1013:Zinc finger protein 746
961:Chr 6: 48.04 – 48.06 Mb
1034:, is encoded by the
561:nucleic acid binding
232:Chromosome 6 (mouse)
130:Chromosome 7 (human)
1043:Parkinson's disease
1220:This article on a
763:ENSMUSG00000057691
601:Biological process
575:Cellular component
519:Molecular function
94:ZNF746 - orthologs
1241:
1240:
1010:
1009:
1006:
1005:
979:
978:
944:
943:
915:
914:
881:
880:
852:
851:
814:
813:
795:
794:
769:
768:
750:
749:
724:
723:
705:
704:
653:
652:
556:metal ion binding
503:
502:
499:
498:
477:
476:
464:
463:
402:
401:
379:bone marrow cells
300:
299:
199:
198:
1291:
1262:
1255:
1248:
1216:
1209:
1199:
1198:
1191:
1185:
1184:
1174:
1164:
1140:
1134:
1133:
1122:
1116:
1115:
1104:
1098:
1088:
1077:
1067:
992:
991:
963:
956:
939:
919:
910:
890:
886:RefSeq (protein)
876:
856:
847:
823:
799:
780:
754:
735:
709:
690:
659:
509:
488:
473:
437:genital tubercle
413:
411:Top expressed in
406:
351:
349:Top expressed in
344:
323:
306:
296:
283:
272:
257:
250:
244:
233:
221:
205:
195:
182:
171:
156:
149:
143:
132:
118:
102:
96:
47:
40:
19:
1299:
1298:
1294:
1293:
1292:
1290:
1289:
1288:
1269:
1268:
1267:
1266:
1205:
1203:
1202:
1193:
1192:
1188:
1142:
1141:
1137:
1124:
1123:
1119:
1106:
1105:
1101:
1089:
1080:
1068:
1059:
1054:
1048:
1001:View/Edit Mouse
996:View/Edit Human
959:
952:
949:Location (UCSC)
935:
931:
927:
906:
902:
898:
872:
868:
864:
843:
839:
835:
831:
744:ENSG00000181220
637:
596:
570:
546:protein binding
469:
460:
455:
451:
447:
443:
439:
435:
431:
427:
423:
409:
398:
393:
389:
385:
381:
377:
373:
369:
367:mucosa of ileum
365:
361:
347:
291:
278:
270:
260:
259:
258:
251:
231:
208:Gene location (
190:
177:
169:
159:
158:
157:
150:
128:
105:Gene location (
56:
43:
36:
17:
12:
11:
5:
1297:
1295:
1287:
1286:
1281:
1271:
1270:
1265:
1264:
1257:
1250:
1242:
1239:
1238:
1217:
1201:
1200:
1186:
1155:(5): 689–702.
1135:
1117:
1099:
1078:
1056:
1055:
1053:
1050:
1015:also known as
1008:
1007:
1004:
1003:
998:
988:
987:
981:
980:
977:
976:
974:
972:
965:
964:
957:
950:
946:
945:
942:
941:
923:
922:
916:
913:
912:
894:
893:
887:
883:
882:
879:
878:
860:
859:
853:
850:
849:
827:
826:
820:
816:
815:
812:
811:
803:
802:
796:
793:
792:
784:
783:
777:
771:
770:
767:
766:
758:
757:
751:
748:
747:
739:
738:
732:
726:
725:
722:
721:
713:
712:
706:
703:
702:
694:
693:
687:
681:
680:
675:
670:
666:
665:
655:
654:
651:
650:
639:
638:
636:
635:
630:
625:
620:
615:
610:
604:
602:
598:
597:
595:
594:
589:
584:
578:
576:
572:
571:
569:
568:
563:
558:
553:
548:
543:
538:
533:
528:
522:
520:
516:
515:
505:
504:
501:
500:
497:
496:
493:
492:
485:
479:
478:
475:
474:
466:
465:
462:
461:
459:
458:
454:
450:
446:
442:
438:
434:
430:
426:
422:
418:
415:
414:
403:
400:
399:
397:
396:
392:
388:
384:
380:
376:
372:
368:
364:
360:
356:
353:
352:
340:
339:
331:
320:
314:
313:
310:RNA expression
302:
301:
298:
297:
289:
285:
284:
276:
273:
268:
262:
261:
252:
245:
239:
235:
234:
229:
223:
222:
214:
213:
201:
200:
197:
196:
188:
184:
183:
175:
172:
167:
161:
160:
151:
144:
138:
134:
133:
126:
120:
119:
111:
110:
98:
97:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1296:
1285:
1282:
1280:
1277:
1276:
1274:
1263:
1258:
1256:
1251:
1249:
1244:
1243:
1237:
1235:
1231:
1227:
1223:
1218:
1215:
1211:
1206:
1196:
1190:
1187:
1182:
1178:
1173:
1168:
1163:
1158:
1154:
1150:
1146:
1139:
1136:
1131:
1127:
1121:
1118:
1113:
1109:
1103:
1100:
1096:
1092:
1087:
1085:
1083:
1079:
1075:
1071:
1066:
1064:
1062:
1058:
1051:
1049:
1046:
1044:
1040:
1037:
1033:
1029:
1026:
1022:
1018:
1014:
1002:
997:
993:
989:
986:
982:
975:
973:
970:
966:
962:
958:
955:
951:
947:
940:
938:
934:
930:
924:
920:
917:
911:
909:
905:
901:
895:
891:
888:
884:
877:
875:
871:
867:
861:
857:
854:
848:
846:
842:
838:
834:
828:
824:
821:
819:RefSeq (mRNA)
817:
810:
809:
804:
800:
797:
791:
790:
785:
781:
778:
776:
772:
765:
764:
759:
755:
752:
746:
745:
740:
736:
733:
731:
727:
720:
719:
714:
710:
707:
701:
700:
695:
691:
688:
686:
682:
679:
676:
674:
671:
667:
664:
660:
656:
649:
645:
640:
634:
631:
629:
626:
624:
621:
619:
616:
614:
611:
609:
606:
605:
603:
600:
599:
593:
590:
588:
585:
583:
580:
579:
577:
574:
573:
567:
564:
562:
559:
557:
554:
552:
549:
547:
544:
542:
539:
537:
534:
532:
529:
527:
524:
523:
521:
518:
517:
514:
513:Gene ontology
510:
506:
494:
489:
486:
484:
480:
472:
467:
456:
452:
448:
444:
440:
436:
432:
428:
424:
420:
419:
416:
412:
407:
404:
394:
390:
386:
382:
378:
374:
370:
366:
362:
358:
357:
354:
350:
345:
342:
341:
338:
336:
332:
330:
329:
325:
324:
321:
319:
315:
311:
307:
303:
295:
290:
286:
282:
277:
271:6|6 B2.3
267:
263:
256:
249:
243:
236:
228:
224:
220:
215:
211:
206:
202:
194:
189:
185:
181:
176:
166:
162:
155:
148:
142:
135:
131:
125:
121:
117:
112:
108:
103:
99:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
1234:expanding it
1226:chromosome 7
1219:
1204:
1189:
1152:
1148:
1138:
1129:
1120:
1111:
1102:
1047:
1035:
1020:
1016:
1012:
1011:
937:NP_001348991
933:NP_001334071
929:NP_001156947
926:
908:NP_001350446
900:NP_001156946
897:
874:NM_001362062
870:NM_001347142
866:NM_001163475
863:
845:NM_001394198
841:NM_001363517
833:NM_001163474
830:
806:
787:
761:
742:
716:
697:
677:
672:
445:spermatocyte
429:otic vesicle
421:otic placode
391:right testis
333:
326:
191:149,497,817
178:149,472,696
53:External IDs
1025:zinc finger
536:DNA binding
453:Paneth cell
433:granulocyte
395:sural nerve
383:left testis
363:granulocyte
292:48,063,527
279:48,039,329
31:Identifiers
1273:Categories
1097:, May 2017
1076:, May 2017
1052:References
337:(ortholog)
74:HomoloGene
1224:on human
1030:that, in
904:NP_689770
837:NM_152557
663:Orthologs
582:cytoplasm
82:GeneCards
1181:21376232
1093:–
1072:–
985:Wikidata
642:Sources:
375:monocyte
1172:3063894
1095:Ensembl
1074:Ensembl
1028:protein
1023:) is a
775:UniProt
730:Ensembl
669:Species
648:QuickGO
592:nucleus
449:condyle
425:saccule
312:pattern
70:1916478
38:Aliases
1179:
1169:
1036:ZNF746
1032:humans
971:search
969:PubMed
808:Q3U133
789:Q6NUN9
699:155061
685:Entrez
483:BioGPS
371:spleen
170:7q36.1
86:ZNF746
62:613914
45:ZNF746
22:ZNF746
1228:is a
1021:PARIS
718:69228
678:Mouse
673:Human
644:Amigo
457:fossa
441:blood
359:blood
335:Mouse
328:Human
275:Start
210:Mouse
174:Start
107:Human
78:19783
1230:stub
1222:gene
1177:PMID
1149:Cell
1039:gene
318:Bgee
266:Band
227:Chr.
165:Band
124:Chr.
58:OMIM
1167:PMC
1157:doi
1153:144
491:n/a
288:End
187:End
90:OMA
66:MGI
1275::
1175:.
1165:.
1151:.
1147:.
1128:.
1110:.
1081:^
1060:^
1045:.
646:/
294:bp
281:bp
193:bp
180:bp
88:;
84::
80:;
76::
72:;
68::
64:;
60::
1261:e
1254:t
1247:v
1236:.
1197:.
1183:.
1159::
1132:.
1114:.
1019:(
212:)
109:)
92::
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