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A study on molecular markers in human aortic endothelial cells published that aglycone stopped cell migration but not monocyte adhesion, which is the initial step of atherosclerotic plaque formation. Another study exploring the benefits of extra virgin olive oil consumption in preventing age-related
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GimĂ©nez-Bastida JA, González-SarrĂas A, Larrosa M, Tomás-Barberán F, EspĂn JC, GarcĂa-Conesa MT (May 2012). "Ellagitannin metabolites, urolithin A glucuronide and its aglycone urolithin A, ameliorate TNF-α-induced inflammation and associated molecular markers in human aortic endothelial cells".
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A way to identify aglycone is proposed to extract it from Agave spp. by using H-NMR and
Heteronuclear multiple bond correlation (HMBC) experiments. The HMBC experiment can be combined with other techniques such as mass spectrometry to further examine the structure and the function of aglycone.
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Samples of glycones and glycosides from limonoids can be simultaneously quantified through a high performance liquid chromatography (HPLC) method, where a binary solvent system and a diode array detector separate and detect them at a sensitivity of 0.25-0.50 ÎĽg.
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neurodegenerative diseases found aglycone greatly increased the cognitive performance of mice. The aglycone-fed mice displayed strong autophagic reactions, mTOR regulation, and reduced plaque deposits and Ăź-amyloid levels.
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Simonet AM, Durán AG, PĂ©rez AJ, MacĂas FA (January 2021). "Features in the NMR spectra of the aglycones of Agave spp. saponins. HMBC method for aglycone identification (HMAI)".
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Vikram A, Jayaprakasha GK, Patil BS (May 2007). "Simultaneous determination of citrus limonoid aglycones and glucosides by high performance liquid chromatography".
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Grossi C, Rigacci S, Ambrosini S, Ed Dami T, Luccarini I, Traini C, et al. (2013-08-08). Ohno M (ed.).
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is replaced by a hydrogen atom. For example, the aglycone of a
151:"Nomenclature of carbohydrates (IUPAC Recommendations 1996)"
200:. Vol. 67 (2nd ed.). 1997. p. 1312.
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198:IUPAC Compendium of Chemical Terminology
292:Molecular Nutrition & Food Research
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352:10.1371/journal.pone.0071702
149:McNaught AD (January 1996).
415:Glycosides by aglycone type
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155:Pure and Applied Chemistry
268:10.1016/j.aca.2007.03.029
168:10.1351/pac199668101919
55:(top) and its aglycone
51:Chemical structures of
410:Carbohydrate chemistry
304:10.1002/mnfr.201100677
256:Analytica Chimica Acta
213:Phytochemical Analysis
183:on 12 November 2016.
115:Clinical significance
396:at Wikimedia Commons
82:remaining after the
394:Glycoside aglycones
343:2013PLoSO...871702G
392:Media related to
161:(10): 1919–2008.
92:cardiac glycoside
80:chemical compound
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136:References
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241:219549980
185:2-Carb-33
130:Glucoside
102:Detection
88:glycoside
78:) is the
60:(bottom)
18:Aglycones
371:23951225
331:PLOS ONE
312:22648625
276:17448343
233:32515107
177:19741698
124:See also
68:aglycone
362:3738517
339:Bibcode
96:steroid
72:aglycon
53:digoxin
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