483:
460:
49:
40:
836:
Wexner SD, Beck DE, Baron TH, Fanelli RD, Hyman N, Shen B, Wasco KE (June 2006). "A consensus document on bowel preparation before colonoscopy: prepared by a task force from the
American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the
757:
When bisacodyl is administered orally, it is usually taken at breakfast. Oral administration is known to produce no action for more than eight hours and then to work suddenly and relatively quickly. This is especially true if more than 10 mg is taken at one time. Normally, the dosage is 5 or
766:. Two suppositories can be inserted at once if a very strong, purgative, enema-like result is needed. A few hours after the initial evacuation, there can be a secondary action which will continue as long as there is unexpelled bisacodyl present in the rectum.
761:
When administered rectally in suppository form, it is usually effective in 15 to 60 minutes. For optimal use, if used as a suppository, it is recommended that bisacodyl be given after breakfast to synchronize with the
136:
1488:
607:
71:
912:"Polyethylene glycol versus vegetable oil based bisacodyl suppositories to initiate side-lying bowel care: a clinical trial in persons with spinal cord injury"
563:
549:
1607:
670:
1066:
1140:
628:
583:
273:
176:
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734:
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379:
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591:
InChI=1S/C22H19NO4/c1-15(24)26-19-10-6-17(7-11-19)22(21-5-3-4-14-23-21)18-8-12-20(13-9-18)27-16(2)25/h3-14,22H,1-2H3
1450:
1000:
782:
745:, or 5 mg pediatric suppositories. It is also available as a 1.25 US fluid ounces (37 ml) pre-packaged
1592:
1133:
121:
478:
1445:
1304:
1118:
682:
808:"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)"
1271:
199:
758:
10 mg, but up to 30 mg can be taken for complete cleansing of the bowel before a procedure.
428:
807:
242:
1455:
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61:
953:"Methods and techniques: The use of Bisacodyl suppositories in preparation for sigmoidoscopy"
1508:
1319:
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1008:
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to produce a bowel movement. It is typically prescribed for relief of episodic and chronic
388:
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662:. It was first used as a laxative in 1953 because of its structural similarity to
651:, as well as part of bowel preparation before medical examinations, such as for a
39:
328:
81:
1551:
1536:
1513:
1309:
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89:
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World Health
Organization model list of essential medicines: 22nd list (2021)
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1561:
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1498:
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1337:
1332:
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1198:
1154:
888:
875:
Wald A (January 2016). "Constipation: Advances in
Diagnosis and Treatment".
255:
75:
1103:
986:
896:
858:
697:
is negligible; stimulant laxatives mainly promote evacuation of the colon.
260:
primarily in the feces, systemically absorbed drug is excreted in the urine
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911:
31:
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690:
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339:
1013:
968:
693:; it increases fluid and salt secretion. The action of bisacodyl on the
348:
17:
1430:
1213:
837:
Society of
American Gastrointestinal and Endoscopic Surgeons (SAGES)".
314:
419:
234:
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770:
746:
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539:
399:
1122:
185:
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815:
749:
containing a 10 mg delivered dose of liquid bisacodyl.
444:
1108:
285:
4,4'-(pyridin-2-ylmethylene)bis(4,1-phenylene) diacetate
1033:
Engelhorn R, Seeger E, Zwaving JH (2000). "Laxatives".
671:
614:
741:. It is usually sold as 5 mg tablets, 10 mg
281:(pyridin-2-ylmethanediyl)dibenzene-4,1-diyl diacetate
1529:
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88:
70:
60:
55:
910:Stiens SA, Luttrel W, Binard JE (November 1998).
327:
302:
1035:Ullmann's Encyclopedia of Industrial Chemistry
773:, it is usually effective in 5 to 20 minutes.
1134:
1099:Bisacodyl,00.html Bisacodyl at Drugdigest.org
571:O=C(Oc1ccc(cc1)C(c2ccc(OC(=O)C)cc2)c3ncccc3)C
8:
705:Bisacodyl is marketed under the trade names
30:
689:, i.e., colonic contractions. It is also a
1141:
1127:
1119:
870:
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481:
458:
367:
47:
38:
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1024:
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454:
347:
278:
94:
1353:Magnesium hydroxide (milk of magnesia)
472:
29:
1007:. Geneva: World Health Organization.
427:
80:
7:
158:
148:
1104:Bisacodyl Consumer Drug Information
407:
318:
25:
66:Fleet, Dulcolax, Brooklax, others
639:drug. It works directly on the
512:
506:
681:Bisacodyl works by stimulating
596:Key:KHOITXIGCFIULA-UHFFFAOYSA-N
1114:Dulcoflex Tablet Uses in Hindi
737:), as well as being available
515:
500:
1:
1067:"Medicine: Cut Out the Liver"
658:Bisacodyl is a derivative of
1608:Bis(4-hydroxyphenyl)methanes
1073:. 1951-04-16. Archived from
649:neurogenic bowel dysfunction
635:that is used as a stimulant
959:. British Medical Journal.
769:As a commercially prepared
735:Carter's Little Liver Pills
1624:
1451:Sodium lauryl sulfoacetate
1017:. WHO/MHP/HPS/EML/2021.02.
839:Gastrointestinal Endoscopy
647:and for the management of
490:Chemical and physical data
1001:World Health Organization
851:10.1016/j.gie.2006.03.918
783:Diphenyl-2-pyridylmethane
604:
579:
559:
269:
46:
37:
1149:Drugs for constipation (
1043:10.1002/14356007.a15_183
1037:. Weinheim: Wiley-VCH.
889:10.1001/jama.2015.16994
1244:Bulk-forming laxatives
1272:Polycarbophil calcium
929:10.1038/sj.sc.3100702
731:Carter's Little Pills
1446:Sodium laurilsulfate
1603:2-Pyridyl compounds
1383:Polyethylene glycol
1343:Magnesium carbonate
1297:Lubricant laxatives
1186:Stimulant laxatives
969:10.1136/gut.5.3.271
677:Mechanism of action
34:
1483:Oxycodone/naloxone
1471:Opioid antagonists
1363:Magnesium peroxide
1234:Sodium picosulfate
1077:on 8 November 2007
764:gastrocolic reflex
1580:
1579:
1368:Magnesium sulfate
1348:Magnesium citrate
1320:Osmotic laxatives
1109:Dulcolax Laxative
951:Evans IL (1964).
622:
621:
550:Interactive image
440:CompTox Dashboard
198:In general:
189:
16:(Redirected from
1615:
1509:Methylnaltrexone
1456:Sodium phosphate
1393:Sodium phosphate
1229:Senna glycosides
1143:
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812:nctr-crs.fda.gov
804:
707:Dulcolax/Durolax
691:contact laxative
660:triphenylmethane
633:organic compound
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200:Over-the-counter
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1403:Sodium tartrate
1378:Pentaerythritol
1358:Magnesium oxide
1314:
1305:Liquid paraffin
1291:
1267:Methylcellulose
1238:
1224:Phenolphthalein
1180:
1168:Stool softeners
1162:
1147:
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701:Available forms
695:small intestine
683:enteric neurons
679:
664:phenolphthalein
613:
611:
608:(what is this?)
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219:Bioavailability
211:Pharmacokinetic
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1547:Oxyphenisatine
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1219:Oxyphenisatine
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1093:External links
1091:
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992:
943:
922:(11): 777–81.
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864:
845:(7): 894–909.
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753:Administration
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1287:Syrup of figs
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1252:Dietary fiber
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743:suppositories
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669:It is on the
667:
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473:ECHA InfoCard
469:
461:
457:
456:DTXSID1022681
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56:Clinical data
54:
50:
45:
41:
36:
19:
1557:Prucalopride
1542:Lubiprostone
1425:
1193:
1079:. Retrieved
1075:the original
1070:
1061:
1034:
1014:10665/345533
1004:
995:
960:
956:
946:
919:
915:
905:
880:
876:
842:
838:
831:
819:. Retrieved
811:
802:
768:
760:
756:
730:
726:
722:
718:
714:
710:
706:
704:
680:
668:
657:
645:constipation
624:
623:
612:
606:
243:Elimination
177:Legal status
171:Legal status
1552:Plecanatide
1537:Linaclotide
1514:Naldemedine
1310:Mineral oil
916:Spinal Cord
771:micro-enema
739:generically
687:peristalsis
653:colonoscopy
533: g·mol
479:100.009.132
265:Identifiers
90:MedlinePlus
62:Trade names
1587:Categories
1572:Ulimorelin
1504:Bevenopran
1209:Castor oil
1155:cathartics
1081:2010-04-26
1052:3527306730
879:(Review).
794:References
788:Cyclofenil
733:(formerly
538:3D model (
526:Molar mass
389:10X0709Y6I
360:ChemSpider
295:CAS Number
274:IUPAC name
237:-mediated)
229:Metabolism
1598:Laxatives
1567:Tenapanor
1562:Tegaserod
1519:Naloxegol
1499:Axelopran
1494:Alvimopan
1426:Bisacodyl
1338:Laminarid
1333:Lactulose
1277:Sterculia
1262:Ispaghula
1199:Bisoxatin
1194:Bisacodyl
1151:laxatives
963:: 271–3.
727:Correctol
685:to cause
625:Bisacodyl
429:ChEMBL942
256:Excretion
245:half-life
131:or rectal
122:Routes of
104:Pregnancy
82:Monograph
76:Drugs.com
32:Bisacodyl
1479:Naloxone
1461:Sorbitol
1436:Glycerol
1408:Sorbitol
1387:macrogol
1373:Mannitol
1328:Lactitol
1282:Triticum
1257:Ethulose
1176:Docusate
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859:16733101
777:See also
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637:laxative
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340:DrugBank
304:603-50-9
250:16 Hours
137:ATC code
129:By mouth
106:category
27:Laxative
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1489:PAMORAs
1431:Dantron
1214:Dantron
1204:Cascara
978:1552120
938:9848486
723:Alophen
531:361.397
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349:DB09020
315:PubChem
233:Liver (
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965:doi
957:Gut
924:doi
885:doi
881:315
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283:OR
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