614:
591:
563:
38:
4196:
1671:
1114:, which is a stimulant laxative), Ex-Lax Stool Softener, Fleet Sof-Lax, Genasoft, Kasof, Laxa-basic, Modane Soft, Octycine-100, Pedia-Lax, Preferred Plus Pharmacy Stool Softener, Regulax SS, Sulfalax Calcium, Sur-Q-Lax, Surfak Stool Softener, and Therevac-SB. Generic preparations are also available.
1206:
As a surfactant, docusate sodium is or has been commercialized under many brand names, including DSSj
Aerosol OT, Alphasol OT, Colace, Complemix, Coprol, Dioctylal, Dioctyl-Medo Forte, Diotilan, Diovac, Disonate, Doxinate, Doxol, Dulsivac, Molatoc, Molofac, Nevax, Norval, Regutol, Softili, Solusol,
1109:
In the U.S., docusate sodium for pharmaceutical use is available under multiple brand names: Aqualax, Calube, Colace, Colace Micro-Enema, Correctol
Softgel Extra Gentle, DC-240, Dialose, Diocto, Dioctocal, Dioctosoftez, Dioctyn, Dionex, Doc-Q-Lace, Docu Soft, Docucal, Doculax, Docusoft S, DOK, DOS,
1558:
were in the range of 43–75 mg/L. Combinations of the fluorinated compounds with dioctyl sodium sulfosuccinate showed mid to highly synergistic effects in most settings, meaning that such combinations are significantly more toxic than the individual substances.
2639:
Rosal R, Rodea-Palomares I, Boltes K, Fernández-Piñas F, Leganés F, Petre A (September 2010). "Ecotoxicological assessment of surfactants in the aquatic environment: combined toxicity of docusate sodium with chlorinated pollutants".
1179:. The highest amount found in food products is 0.5% by weight, which include pasteurized cheese spreads, cream cheeses and salad dressings. The FDA also approved its use as a wetting agent or solubilizer for flavoring agents in
3185:
688:
4236:
189:
3178:
1451:
Ingestion may cause the side effects described above, such as diarrhea, intestinal bloating, and occasionally cramping pains. Dioctyl sodium sulfosuccinate is not known to be
2498:
3069:
2119:
680:
3171:
71:
732:
777:
as salt: InChI=1S/C20H38O7S.Na/c1-5-9-11-16(7-3)14-26-19(21)13-18(28(23,24)25)20(22)27-15-17(8-4)12-10-6-2;/h16-18H,5-15H2,1-4H3,(H,23,24,25);/q;+1/p-1
1575:) of 0.56 mg/L after 48 hours for the pure substance. It is only slightly to moderately toxic for rainbow trout fingerlings, and slightly toxic for
4226:
948:
However, its effectiveness for constipation is poorly supported by evidence. Multiple studies have found docusate to be no more effective than a
1777:"Dioctyl Sulfosuccinate or Docusate (Calcium or Sodium) for the Prevention or Management of Constipation: A Review of the Clinical Effectiveness"
1298:
Solubility of dioctyl sodium sulfosuccinate in water is 14 g/L at 25 °C, increasing to 55 g/L at 70 °C. Solubility is better in less
2261:
2214:
864:
1649:
2721:
2306:"American gastroenterological association institute medical position statement on the use of gastrointestinal medications in pregnancy"
1127:
In India, preparations include
Laxatin by Alembic, Doslax by Raptakos Laboratories, Cellubril by AstraZeneca, and Laxicon by Stadmed.
2623:
1864:
Ramkumar D, Rao SS (April 2005). "Efficacy and safety of traditional medical therapies for chronic constipation: systematic review".
1143:
without the use of co-surfactants, and it has a rich variety of aqueous-phase behavior including multiple liquid crystalline phases.
1051:
Serious allergic reactions may occur with the drug. The most severe side effect of docusate, although very rare, is rectal bleeding.
2604:
2411:
2384:
2288:
1955:
1928:
758:
1097:
studies suggest that docusate inhibits fluid absorption or stimulates secretion in the portion of the small intestine known as the
1117:
In the UK, dioctyl sodium sulfosuccinate is sold under the brand name
Docusol (Typharm Ltd) and DulcoEase (Boehringer Ingelheim).
3980:
3205:
2123:
2070:
1619:
766:
InChI=1S/C20H38O7S/c1-5-9-11-16(7-3)14-26-19(21)13-18(28(23,24)25)20(22)27-15-17(8-4)12-10-6-2/h16-18H,5-15H2,1-4H3,(H,23,24,25)
1531:
1152:
942:
When administered by mouth, a bowel movement often occurs in 1 to 3 days, while rectal use may be effective within 20 minutes.
311:
219:
103:
3662:
2010:
1806:
1079:, allowing more intestinal water and fat to combine with the stool. This decreases the strain and discomfort associated with
2506:
2040:
1155:
as a "generally recognized as safe" (GRAS) additive. It is used in a variety of food products, as a surface active agent,
2690:
4241:
4216:
4172:
1536:
445:
3401:
1669:, Caryl CR, Jaeger AO, "Detergent composition", issued 21 November 1939, assigned to American Cyanamid
3707:
3194:
570:
1110:
Doss-Relief, DSS, Dulcolax - Stool
Softener (not to be confused with another drug marketed under the Dulcolax brand,
2348:
122:
4186:
4130:
3482:
3477:
3031:
1690:
Wilson JL, Dickinson DG (May 1955). "Use of dioctyl sodium sulfosuccinate (aerosol O.T.) for severe constipation".
952:
for improving constipation. Others have found it to be less useful for the treatment of chronic constipation than
3965:
3512:
3351:
1971:
1544:
1390:
4090:
4005:
2230:
875:
was the 275th most commonly prescribed medication in the United States, with more than 800,000 prescriptions.
4231:
2714:
1195:
159:
20:
3221:
1139:
in a wide range of applications, often under the name
Aerosol-OT. It is unusual in that it is able to form
609:
3652:
3281:
3026:
2885:
2699:
2092:
Friedman M (October 1956). "Dioctyl sodium sulfosuccinate (doxinate) in chronic functional constipation".
1540:
1480:
1086:
It does not stay in the gastrointestinal tract, but is absorbed into the bloodstream and excreted via the
991:
853:
539:
531:
2528:
3411:
3406:
3396:
2852:
1281:
903:
264:
258:
233:
170:
3497:
3487:
2553:
Flynn PF (2004). "Multidimensional multinuclear solution NMR studies of encapsulated macromolecules".
1666:
867:. In 2021, it was the 133rd most commonly prescribed medication in the United States, with more than 4
4060:
3835:
3807:
3797:
3492:
3416:
3391:
2649:
2283:(9th ed.). Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins. p. 1651.
899:
3831:
3637:
3537:
3461:
3036:
2973:
2963:
2933:
2923:
586:
328:
166:
3261:
4221:
4110:
3865:
3666:
3431:
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3197:
3063:
2943:
2814:
2766:
2707:
2468:
1889:
1645:
1221:
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245:
133:
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1920:
3572:
3451:
3331:
2278:
4055:
3815:
3752:
3692:
3522:
3051:
2948:
2928:
2784:
2665:
2600:
2444:
2407:
2401:
2380:
2327:
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2210:
2176:
2101:
1951:
1945:
1924:
1881:
1839:
1784:
1753:
1707:
1576:
1503:
1335:
1299:
1156:
983:
884:
53:
3840:
3446:
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511:
4100:
3820:
3702:
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3517:
3507:
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3421:
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3089:
2900:
2847:
2657:
2592:
2562:
2477:
2436:
2372:
2317:
2166:
2158:
1979:
1873:
1829:
1821:
1743:
1699:
1394:
1374:
1180:
813:
719:
626:
503:
293:
275:
1517:
In a 2010 study, dioctyl sodium sulfosuccinate exhibited higher toxicity against bacteria (
462:
454:
434:
426:
337:
4200:
3777:
3672:
3552:
2983:
2958:
2938:
2809:
2804:
2627:
2620:
2352:
1732:"Things We Do for No Reason: Prescribing Docusate for Constipation in Hospitalized Adults"
1548:
1519:
1486:
1315:
1041:
872:
283:
3163:
2209:(in German). Vol. 2 (23 ed.). Eschborn, Germany: Govi Pharmazeutischer Verlag.
613:
590:
345:
2686:
2653:
2466:, Penfold J (November 2000). "What Is So Special about Aerosol-OT? 1. Aqueous Systems".
562:
4125:
4045:
3915:
3772:
3627:
3592:
3251:
3127:
2978:
2799:
2748:
2376:
2171:
2146:
1913:
1834:
1351:
1285:
1273:
1140:
963:
medication, although prolonged use may cause irritation of the gastrointestinal tract.
182:
2661:
2596:
1703:
1615:
832:, by mouth or rectally. Some studies claim that docusate is not more effective than a
81:
4210:
4065:
3940:
3825:
3787:
3682:
3647:
3582:
3381:
3341:
3241:
2867:
2832:
2463:
2062:
1877:
1568:
1507:
1499:
1363:
1355:
1292:
1242:
1164:
1121:
1018:
1007:
857:
845:
709:
602:
378:
95:
2280:
Drugs in pregnancy and lactation : a reference guide to fetal and neonatal risk
2256:(in German) (41st ed.). Vienna: Österreichischer Apothekerverlag. p. 316.
1893:
1093:
The effect of docusate may not necessarily be all due to its surfactant properties.
4150:
4120:
4095:
4050:
3995:
3990:
3975:
3970:
3960:
3955:
3880:
3782:
3762:
3747:
3742:
3737:
3722:
3617:
3607:
3436:
3376:
3311:
3306:
3301:
3296:
3276:
3266:
3137:
3122:
2739:
2440:
2427:
Whiffen AJ (1946). "Aerosol OT in the preparation of microscopic mounts of fungi".
1825:
1311:
1080:
1014:
936:
924:
883:
Sodium docusate was patented in 1937 by
Coleman R. Caryl and Alphons O. Jaeger for
836:
for improving constipation. Other docusate salts with medical use include those of
202:
197:
2002:
1807:"Laxatives for the management of constipation in people receiving palliative care"
370:
2322:
2305:
4135:
4105:
4085:
4035:
3910:
3905:
3890:
3860:
3687:
3642:
3602:
3597:
3547:
3542:
3527:
3366:
3326:
3231:
3132:
3117:
3094:
2890:
2566:
2032:
1776:
1476:
1402:
1343:
1168:
1120:
In
Australia, dioctyl sodium sulfosuccinate is sold as Coloxyl and Coloxyl with
1087:
89:
4115:
4075:
4020:
4010:
3950:
3935:
3920:
3900:
3875:
3870:
3850:
3845:
3802:
3792:
3757:
3732:
3712:
3677:
3656:
3612:
3587:
3371:
3336:
3321:
3316:
3285:
3246:
3226:
3152:
3084:
2789:
1472:
1452:
1327:
1307:
1176:
1172:
1136:
987:
932:
849:
656:
417:
177:
1976:
World Health
Organization model list of essential medicines: 22nd list (2021)
1291:
The compound is a white, wax-like, plastic solid, with an odor suggestive of
406:
4040:
4030:
4025:
4015:
4000:
3985:
3930:
3885:
3855:
3717:
3697:
3622:
3562:
3557:
3426:
3356:
3346:
3291:
3147:
3142:
3099:
3079:
3074:
3006:
2918:
2913:
2857:
2779:
2774:
2735:
2406:(27 ed.). Burlington, Ma.: Jones & Bartlett Learning. p. 112.
1460:
1398:
1347:
1160:
1111:
1094:
1048:, Efficacy decreases with long-term use, and may cause poor bowel function.
1003:
979:
928:
888:
841:
75:
2669:
2448:
2331:
2180:
2162:
2105:
1885:
1843:
1805:
Candy B, Jones L, Larkin PJ, Vickerstaff V, Tookman A, Stone P (May 2015).
1788:
1757:
1711:
37:
2345:
3945:
3925:
3895:
3767:
3727:
3577:
3567:
3441:
3059:
3041:
3016:
2988:
2967:
2953:
2908:
2877:
2842:
2837:
2824:
2731:
2499:"GRAS Notice Inventory Agency Response Letter GRAS Notice No. GRN 000006"
1525:
1359:
1339:
1322:, although this is a rather polar solvent. It is also highly soluble in
1319:
1277:
1045:
953:
829:
825:
821:
558:
550:
389:
117:
29:
2238:
1984:
898:
Its use for the treatment of constipation was first proposed in 1955 by
398:
4155:
4140:
4070:
3532:
3256:
3011:
2794:
1491:
1456:
1331:
1303:
1192:
1098:
1060:
1037:
972:
949:
837:
833:
699:
356:
2481:
2403:
Tarascon pocket pharmacopoeia : 2013 classic shirt-pocket edition
1748:
1731:
2693:
1323:
960:
939:, it can help avoid pain caused by straining during bowel movements.
522:
1551:
inhibition of the bacteria and growth inhibition of the algae, the
483:
2998:
2862:
2587:
1370:
1076:
1022:
796:
687:
679:
670:
494:
945:
Sodium docusate is recommended as a stool softener for children.
1644:
American Society of Health-System Pharmacists (15 August 2011).
1552:
1378:
1183:
and non-carbonated drinks at levels up to 10 parts per million.
1059:
Docusate might increase resorption of other drugs, for example,
1028:
When taken by mouth it should be ingested with plenty of water.
473:
239:
3167:
2703:
1919:. Burlington, MA: Jones & Bartlett Learning. 2013. p.
252:
112:
3021:
1950:. Endicott, N.Y.: Synapse information resources. p. 375.
1191:
Sodium docusate is the most widely used surfactant in reverse
1036:
Side effects are uncommon and typically mild, and may include
2367:
Shaw D (2017). "Drugs Acting on the Gastrointestinal Tract".
971:
Docusate sodium, when used with ear syringing, may help with
746:
as salt: .S(=O)(=O)C(C(=O)OCC(CC)CCCC)CC(=O)OCC(CC)CCCC
575:
1389:
Sodium dioctyl sulfosuccinate can be obtained by treating
1002:
Docusate sodium is approved and recommended as safe during
144:
3206:
959:
The medication may be given to people who are receiving
319:
1,4-bis(2-ethylhexyloxy)-1,4-dioxobutane-2-sulfonic acid
228:
1151:
Dioctyl sodium sulfosuccinate has been approved by the
865:
World Health Organization's List of Essential Medicines
2200:
2198:
2196:
2194:
2192:
2190:
1997:
1995:
927:, acting as a laxative and stool softener. In painful
795:
is the common chemical and pharmaceutical name of the
4184:
2231:"How effective is docusate as a cerumenolytic agent?"
1618:. The American Society of Health-System Pharmacists.
1471:
Dioctyl sodium sulfosuccinate is of low toxicity for
1075:, which works by reducing the surface tension of the
871:
million prescriptions. In 2021, the combination with
551:
923:
The main medical use of docusate sodium is to treat
3460:
3204:
3110:
3050:
2997:
2899:
2876:
2823:
2765:
2747:
1583:27 mg/L of a 60% formulation after 48 hours).
718:
708:
698:
668:
655:
625:
620:
601:
569:
549:
521:
493:
472:
444:
416:
388:
355:
327:
302:
292:
282:
274:
218:
213:
188:
176:
158:
132:
102:
88:
70:
62:
52:
47:
1912:
714:153 to 157 °C (307 to 315 °F) 173-179 °C
2591:. Vol. 2. Academic Press. pp. 199–219.
1535:) than did a number of fluorinated surfactants (
1295:. It starts to decompose at about 220 °C.
975:removal, particularly in the case of impaction.
377:
369:
344:
336:
1859:
1857:
1855:
1853:
887:, which commercialized it for many years as a
740:CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S(O)(=O)=O
4237:World Health Organization essential medicines
3179:
2715:
2094:American Practitioner and Digest of Treatment
1725:
1723:
1721:
19:"Colace" redirects here. For other uses, see
8:
2582:
2580:
2578:
2576:
2529:"CFR - Code of Federal Regulations Title 21"
2503:Center for Food Safety and Applied Nutrition
2362:
2360:
1207:Sulfimel DOS, Vatsol OT, Velmol, and Waxsol
121:
28:
3462:
2369:Pharmacology and Therapeutics for Dentistry
1907:
1905:
1903:
1814:The Cochrane Database of Systematic Reviews
1800:
1798:
1771:
1769:
1767:
1730:Fakheri RJ, Volpicelli FM (February 2019).
1692:Journal of the American Medical Association
1318:(25 °C). It also is highly soluble in
1135:Dioctyl sodium sulfosuccinate is used as a
1013:Docusate is not recommended in people with
3513:Allopregnanedione (5α-dihydroprogesterone)
3186:
3172:
3164:
2722:
2708:
2700:
2621:Docusate sodium Material Safety Data Sheet
2493:
2491:
1685:
1683:
1681:
1661:
1659:
1639:
1637:
1610:
1608:
1606:
1604:
1602:
1600:
1598:
1596:
612:
589:
561:
433:
425:
2321:
2170:
2063:"Senna; Docusate - Drug Usage Statistics"
1983:
1833:
1747:
906:, and quickly popularized under the name
461:
453:
3211:Tooltip Constitutive androstane receptor
2589:InAnalytical Profiles of Drug Substances
1866:The American Journal of Gastroenterology
1438:
1267:
1263:
1259:
1255:
1251:
1247:
1236:
4191:
2145:Portalatin M, Winstead N (March 2012).
1592:
1090:after undergoing extensive metabolism.
763:
737:
585:
405:
397:
316:
94:
3966:Pregnanedione (5β-dihydroprogesterone)
3352:Pregnanedione (5β-dihydroprogesterone)
2934:Magnesium hydroxide (milk of magnesia)
2371:(Seventh ed.). pp. 404–416.
1652:from the original on 5 September 2015.
1622:from the original on 23 September 2015
1571:with a median lethal concentration (LC
603:
27:
2205:Dinnendahl V, Fricke U, eds. (2010).
1978:. Geneva: World Health Organization.
724:1 in 70 parts mg/mL (20 °C)
538:
530:
510:
502:
80:
58:Colace, Ex-Lax Stool Softener, others
7:
2389:– via Elsevier Science Direct.
2147:"Medical management of constipation"
2073:from the original on 18 January 2024
2043:from the original on 20 January 2024
2013:from the original on 15 January 2024
201:
2151:Clinics in Colon and Rectal Surgery
1377:conditions, but are stable against
482:
360:
2555:Prog. Nucl. Magn. Reson. Spectrosc
2377:10.1016/B978-0-323-39307-2.00028-X
2122:. 18 December 2004. Archived from
2033:"Docusate - Drug Usage Statistics"
1567:The substance is highly toxic for
1498:found between 5 mg/L for the
990:in topical preparations and other
978:Sodium docusate is also used as a
844:. Docusate salts are also used as
14:
2662:10.1016/j.chemosphere.2010.05.050
2304:Mahadevan U, Kane S (July 2006).
1704:10.1001/jama.1955.02960040019006a
998:Precautions and contraindications
4194:
1878:10.1111/j.1572-0241.2005.40925.x
1373:groups are easily cleaved under
1276:can be described as the twofold
800:bis(2-ethylhexyl) sulfosuccinate
637:
36:
1532:Pseudokirchneriella subcapitata
1314:, and practically unlimited in
782:Key:APSBXTVYXVQYAB-UHFFFAOYSA-M
771:Key:HNSDLXPSAYFUHK-UHFFFAOYSA-N
4227:Drugs developed by AstraZeneca
3518:Allopregnanolone (brexanolone)
2505:. 20 July 1998. Archived from
2441:10.1080/00275514.1946.12024063
1826:10.1002/14651858.CD003448.pub4
1494:varies widely, with 48-hour LD
1063:(1,8-dihydroxyanthraquinone).
649:
643:
631:
1:
4173:Receptor/signaling modulators
4131:Tropanyl 3,5-dimethulbenzoate
3981:Pregnenolone 16α-carbonitrile
2597:10.1016/S0099-5428(08)60040-4
2323:10.1053/j.gastro.2006.04.048
1781:CADTH Rapid Response Reports
1736:Journal of Hospital Medicine
3708:Dodecylbenzenesulfonic acid
3467:Tooltip Pregnane X receptor
3195:Xenobiotic-sensing receptor
2567:10.1016/j.pnmrs.2004.04.003
816:of this anion, especially
4258:
3032:Sodium lauryl sulfoacetate
1988:. WHO/MHP/HPS/EML/2021.02.
1915:2013 Nurse's Drug Handbook
1502:and 100 mg/L for the
1105:Pharmaceutical brand names
621:Chemical and physical data
18:
4164:
1972:World Health Organization
1947:Handbook of preservatives
1224:of the docusate anion is
754:
728:
307:
35:
16:Laxatives/stool softeners
4091:Testosterone isocaproate
4006:Reverse triiodothyronine
2730:Drugs for constipation (
2254:Austria-Codex Stoffliste
1216:Structure and properties
3483:17α-Hydroxyprogesterone
3478:17α-Hydroxypregnenolone
2626:17 October 2006 at the
1202:Non-medical brand names
802:, also commonly called
21:Colace (disambiguation)
2825:Bulk-forming laxatives
2533:www.accessdata.fda.gov
2163:10.1055/s-0032-1301754
1481:Clibanarius erythropus
804:dioctyl sulfosuccinate
66:Dioctyl sulfosuccinate
3222:6,7-Dimethylesculetin
2853:Polycarbophil calcium
2252:Jasek W, ed. (2008).
2003:"The Top 300 of 2021"
1944:Ash M, Ash I (2004).
1506:. Various species of
982:in the production of
891:under the brand name
820:, are widely used in
3809:Hypericum perforatum
3798:Hetacillin potassium
3027:Sodium laurilsulfate
2400:Hamilton RJ (2013).
2351:16 July 2010 at the
2241:on 23 November 2010.
1514:around 8 mg/L.
860:, among other uses.
4242:2-Ethylhexyl esters
4217:Anionic surfactants
3638:Cyproterone acetate
3538:Amlodipine besylate
2964:Polyethylene glycol
2924:Magnesium carbonate
2878:Lubricant laxatives
2767:Stimulant laxatives
2654:2010Chmsp..81..288R
2207:Arzneistoff-Profile
1067:Mechanism of action
931:conditions such as
720:Solubility in water
32:
4111:Thonzonium bromide
3866:Methylprednisolone
3667:prasterone sulfate
3064:Oxycodone/naloxone
3052:Opioid antagonists
2944:Magnesium peroxide
2815:Sodium picosulfate
2509:on 31 October 2017
1577:harlequin rasboras
1563:Freshwater species
1401:anion adds to the
1302:solvents: 1:30 in
1282:sulfosuccinic acid
1243:2-ethylhexyl group
1222:structural formula
1187:Microencapsulation
1169:solubilizing agent
1167:, processing aid,
1073:anionic surfactant
967:Other medical uses
904:David G. Dickinson
294:Duration of action
246:General sales list
4182:
4181:
3816:Indinavir sulfate
3523:Alpha-Lipoic acid
3498:Δ-Androstenedione
3488:Δ-Androstenedione
3161:
3160:
2949:Magnesium sulfate
2929:Magnesium citrate
2901:Osmotic laxatives
2482:10.1021/la000341q
2476:(23): 8733–8740.
2277:Yaffe SJ (2011).
2263:978-3-85200-190-6
2216:978-3-7741-9846-3
2120:"Docusate sodium"
1749:10.12788/jhm.3124
1646:"Stool Softeners"
1504:common periwinkle
1336:diacetone alcohol
1241:, where R is the
885:American Cyanamid
790:
789:
689:Interactive image
681:Interactive image
571:CompTox Dashboard
559:(thickeners, ...)
263:In general:
256:
243:
231:
148:
115:
4249:
4199:
4198:
4197:
4190:
4101:Thiamylal sodium
3836:γ-linolenic acid
3832:α-Linolenic acid
3830:Linolenic acid:
3821:Lasalocid sodium
3811:(St John's wort)
3703:Docusate calcium
3633:Cyclophosphamide
3508:Allopregnanediol
3493:Δ-Androstenediol
3468:
3464:
3422:Ethinylestradiol
3272:Cyclophosphamide
3212:
3208:
3188:
3181:
3174:
3165:
3090:Methylnaltrexone
3037:Sodium phosphate
2974:Sodium phosphate
2810:Senna glycosides
2724:
2717:
2710:
2701:
2696:Health resource.
2674:
2673:
2636:
2630:
2619:ScienceLab.com:
2617:
2611:
2610:
2584:
2571:
2570:
2550:
2544:
2543:
2541:
2539:
2525:
2519:
2518:
2516:
2514:
2495:
2486:
2485:
2459:
2453:
2452:
2424:
2418:
2417:
2397:
2391:
2390:
2364:
2355:
2342:
2336:
2335:
2325:
2310:Gastroenterology
2301:
2295:
2294:
2274:
2268:
2267:
2249:
2243:
2242:
2237:. Archived from
2227:
2221:
2220:
2202:
2185:
2184:
2174:
2142:
2136:
2135:
2133:
2131:
2116:
2110:
2109:
2089:
2083:
2082:
2080:
2078:
2059:
2053:
2052:
2050:
2048:
2029:
2023:
2022:
2020:
2018:
1999:
1990:
1989:
1987:
1968:
1962:
1961:
1941:
1935:
1934:
1918:
1909:
1898:
1897:
1861:
1848:
1847:
1837:
1811:
1802:
1793:
1792:
1783:. 26 June 2014.
1773:
1762:
1761:
1751:
1727:
1716:
1715:
1687:
1676:
1675:
1674:
1670:
1663:
1654:
1653:
1641:
1632:
1631:
1629:
1627:
1616:"Docusate Salts"
1612:
1529:sp.) and algae (
1490:. Toxicity for
1442:
1436:
1435:
1432:
1426:
1423:
1422:
1421:
1418:
1411:
1395:sodium bisulfite
1271:
1240:
1234:
1233:
1230:
1042:abdominal cramps
870:
691:
683:
663:
651:
645:
639:
633:
616:
605:
594:
593:
579:
577:
565:
553:
542:
534:
514:
506:
486:
465:
457:
437:
429:
409:
401:
381:
373:
363:
362:
348:
340:
288:12 hrs to 5 days
265:Over-the-counter
254:
251:
241:
238:
230:
227:
205:
146:
143:
125:
114:
111:
98:
84:
40:
33:
31:
4257:
4256:
4252:
4251:
4250:
4248:
4247:
4246:
4207:
4206:
4205:
4195:
4193:
4185:
4183:
4178:
4160:
4061:Suberoylanilide
3778:Fluorometholone
3673:Dibunate sodium
3553:Aurothioglucose
3466:
3456:
3392:3,17β-Estradiol
3210:
3200:
3192:
3162:
3157:
3106:
3046:
2993:
2984:Sodium tartrate
2959:Pentaerythritol
2939:Magnesium oxide
2895:
2886:Liquid paraffin
2872:
2848:Methylcellulose
2819:
2805:Phenolphthalein
2761:
2749:Stool softeners
2743:
2728:
2687:Stool Softeners
2683:
2678:
2677:
2638:
2637:
2633:
2628:Wayback Machine
2618:
2614:
2607:
2586:
2585:
2574:
2552:
2551:
2547:
2537:
2535:
2527:
2526:
2522:
2512:
2510:
2497:
2496:
2489:
2461:
2460:
2456:
2426:
2425:
2421:
2414:
2399:
2398:
2394:
2387:
2366:
2365:
2358:
2353:Wayback Machine
2343:
2339:
2303:
2302:
2298:
2291:
2276:
2275:
2271:
2264:
2251:
2250:
2246:
2229:
2228:
2224:
2217:
2204:
2203:
2188:
2144:
2143:
2139:
2129:
2127:
2126:on 21 July 2011
2118:
2117:
2113:
2100:(10): 1588–91.
2091:
2090:
2086:
2076:
2074:
2061:
2060:
2056:
2046:
2044:
2031:
2030:
2026:
2016:
2014:
2001:
2000:
1993:
1970:
1969:
1965:
1958:
1943:
1942:
1938:
1931:
1911:
1910:
1901:
1863:
1862:
1851:
1820:(5): CD003448.
1809:
1804:
1803:
1796:
1775:
1774:
1765:
1729:
1728:
1719:
1689:
1688:
1679:
1672:
1665:
1664:
1657:
1643:
1642:
1635:
1625:
1623:
1614:
1613:
1594:
1589:
1582:
1574:
1565:
1556:
1549:bioluminescence
1520:Vibrio fischeri
1513:
1497:
1487:Crangon crangon
1484:and the shrimp
1469:
1449:
1440:
1433:
1430:
1429:
1427:
1424:
1419:
1416:
1415:
1413:
1409:
1391:dioctyl maleate
1387:
1316:petroleum ether
1269:
1265:
1261:
1257:
1253:
1249:
1245:
1238:
1231:
1228:
1227:
1226:R−O−C(=O)−CH(SO
1225:
1218:
1213:
1204:
1189:
1149:
1133:
1107:
1071:Docusate is an
1069:
1057:
1034:
1000:
969:
921:
916:
900:James L. Wilson
881:
868:
830:stool softeners
818:docusate sodium
786:
783:
778:
775:
772:
767:
762:
761:
750:
747:
744:
741:
736:
735:
694:
661:
648:
642:
636:
597:
573:
545:
517:
489:
468:
440:
412:
384:
359:
351:
323:
320:
315:
314:
284:Onset of action
276:Pharmacokinetic
270:
209:
161:
154:
135:
128:
43:
42:Docusate sodium
24:
17:
12:
11:
5:
4255:
4253:
4245:
4244:
4239:
4234:
4232:Sulfonic acids
4229:
4224:
4219:
4209:
4208:
4204:
4203:
4180:
4179:
4177:
4176:
4169:
4165:
4162:
4161:
4159:
4158:
4153:
4144:
4143:
4138:
4133:
4128:
4126:Troleandomycin
4123:
4118:
4113:
4108:
4103:
4098:
4093:
4088:
4083:
4078:
4073:
4068:
4063:
4058:
4053:
4048:
4046:Spironolactone
4043:
4038:
4033:
4028:
4023:
4018:
4013:
4008:
4003:
3998:
3993:
3988:
3983:
3978:
3973:
3968:
3963:
3958:
3953:
3948:
3943:
3938:
3933:
3928:
3923:
3918:
3916:Norelgestromin
3913:
3908:
3903:
3898:
3893:
3888:
3883:
3878:
3873:
3868:
3863:
3858:
3853:
3848:
3843:
3838:
3828:
3823:
3818:
3813:
3805:
3800:
3795:
3790:
3785:
3780:
3775:
3773:Flucloxacillin
3770:
3765:
3760:
3755:
3750:
3745:
3740:
3735:
3730:
3725:
3720:
3715:
3710:
3705:
3700:
3695:
3690:
3685:
3680:
3675:
3670:
3660:
3650:
3645:
3640:
3635:
3630:
3628:Corticosterone
3625:
3620:
3615:
3610:
3605:
3600:
3595:
3593:Chlorpromazine
3590:
3585:
3580:
3575:
3570:
3565:
3560:
3555:
3550:
3545:
3540:
3535:
3530:
3525:
3520:
3515:
3510:
3505:
3500:
3495:
3490:
3485:
3480:
3471:
3469:
3458:
3457:
3455:
3454:
3449:
3444:
3439:
3434:
3429:
3424:
3419:
3414:
3412:17-Androstanol
3409:
3407:3β-Androstanol
3404:
3402:3α-Androstenol
3399:
3397:3α-Androstanol
3394:
3385:
3384:
3379:
3374:
3369:
3364:
3359:
3354:
3349:
3344:
3339:
3334:
3329:
3324:
3319:
3314:
3309:
3304:
3299:
3294:
3289:
3279:
3274:
3269:
3264:
3259:
3254:
3252:Chlorpromazine
3249:
3244:
3239:
3234:
3229:
3224:
3215:
3213:
3202:
3201:
3193:
3191:
3190:
3183:
3176:
3168:
3159:
3158:
3156:
3155:
3150:
3145:
3140:
3135:
3130:
3128:Oxyphenisatine
3125:
3120:
3114:
3112:
3108:
3107:
3105:
3104:
3103:
3102:
3097:
3092:
3087:
3082:
3077:
3067:
3056:
3054:
3048:
3047:
3045:
3044:
3039:
3034:
3029:
3024:
3019:
3014:
3009:
3003:
3001:
2995:
2994:
2992:
2991:
2986:
2981:
2979:Sodium sulfate
2976:
2971:
2961:
2956:
2951:
2946:
2941:
2936:
2931:
2926:
2921:
2916:
2911:
2905:
2903:
2897:
2896:
2894:
2893:
2888:
2882:
2880:
2874:
2873:
2871:
2870:
2865:
2860:
2855:
2850:
2845:
2840:
2835:
2829:
2827:
2821:
2820:
2818:
2817:
2812:
2807:
2802:
2800:Oxyphenisatine
2797:
2792:
2787:
2782:
2777:
2771:
2769:
2763:
2762:
2760:
2759:
2753:
2751:
2745:
2744:
2729:
2727:
2726:
2719:
2712:
2704:
2698:
2697:
2682:
2681:External links
2679:
2676:
2675:
2631:
2612:
2605:
2572:
2561:(1–2): 31–51.
2545:
2520:
2487:
2454:
2419:
2412:
2392:
2385:
2356:
2337:
2296:
2289:
2269:
2262:
2244:
2222:
2215:
2186:
2137:
2111:
2084:
2054:
2024:
1991:
1963:
1956:
1936:
1929:
1899:
1849:
1794:
1763:
1742:(2): 110–113.
1717:
1677:
1655:
1633:
1591:
1590:
1588:
1585:
1580:
1572:
1564:
1561:
1554:
1511:
1495:
1468:
1467:Marine species
1465:
1448:
1445:
1444:
1443:
1386:
1383:
1364:vegetable oils
1352:methyl acetate
1286:2-ethylhexanol
1274:conjugate acid
1217:
1214:
1212:
1209:
1203:
1200:
1188:
1185:
1148:
1145:
1141:microemulsions
1132:
1129:
1106:
1103:
1068:
1065:
1056:
1053:
1033:
1030:
999:
996:
968:
965:
920:
917:
915:
912:
880:
877:
858:wetting agents
846:food additives
788:
787:
785:
784:
781:
779:
776:
773:
770:
768:
765:
757:
756:
755:
752:
751:
749:
748:
745:
742:
739:
731:
730:
729:
726:
725:
722:
716:
715:
712:
706:
705:
702:
696:
695:
693:
692:
686:as salt:
684:
676:
674:
666:
665:
659:
653:
652:
646:
640:
634:
629:
623:
622:
618:
617:
607:
599:
598:
596:
595:
582:
580:
567:
566:
555:
547:
546:
544:
543:
537:as salt:
535:
527:
525:
519:
518:
516:
515:
509:as salt:
507:
499:
497:
491:
490:
488:
487:
481:as salt:
478:
476:
470:
469:
467:
466:
460:as salt:
458:
450:
448:
442:
441:
439:
438:
432:as salt:
430:
422:
420:
414:
413:
411:
410:
404:as salt:
402:
394:
392:
386:
385:
383:
382:
376:as salt:
374:
366:
364:
353:
352:
350:
349:
343:as salt:
341:
333:
331:
325:
324:
322:
321:
318:
310:
309:
308:
305:
304:
300:
299:
296:
290:
289:
286:
280:
279:
272:
271:
269:
268:
261:
249:
236:
224:
222:
216:
215:
211:
210:
208:
207:
194:
192:
186:
185:
183:Stool softener
180:
174:
173:
164:
162:administration
156:
155:
153:
152:
150:
140:
138:
130:
129:
127:
126:
108:
106:
100:
99:
92:
86:
85:
78:
68:
67:
64:
60:
59:
56:
50:
49:
45:
44:
41:
15:
13:
10:
9:
6:
4:
3:
2:
4254:
4243:
4240:
4238:
4235:
4233:
4230:
4228:
4225:
4223:
4220:
4218:
4215:
4214:
4212:
4202:
4192:
4188:
4175:
4174:
4170:
4167:
4166:
4163:
4157:
4154:
4152:
4149:
4146:
4145:
4142:
4139:
4137:
4134:
4132:
4129:
4127:
4124:
4122:
4119:
4117:
4114:
4112:
4109:
4107:
4104:
4102:
4099:
4097:
4094:
4092:
4089:
4087:
4084:
4082:
4079:
4077:
4074:
4072:
4069:
4067:
4066:Sulfisoxazole
4064:
4062:
4059:
4057:
4054:
4052:
4049:
4047:
4044:
4042:
4039:
4037:
4034:
4032:
4029:
4027:
4024:
4022:
4019:
4017:
4014:
4012:
4009:
4007:
4004:
4002:
3999:
3997:
3994:
3992:
3989:
3987:
3984:
3982:
3979:
3977:
3974:
3972:
3969:
3967:
3964:
3962:
3959:
3957:
3954:
3952:
3949:
3947:
3944:
3942:
3941:Phenobarbital
3939:
3937:
3934:
3932:
3929:
3927:
3924:
3922:
3919:
3917:
3914:
3912:
3909:
3907:
3904:
3902:
3899:
3897:
3894:
3892:
3889:
3887:
3884:
3882:
3879:
3877:
3874:
3872:
3869:
3867:
3864:
3862:
3859:
3857:
3854:
3852:
3849:
3847:
3844:
3842:
3839:
3837:
3833:
3829:
3827:
3826:Levothyroxine
3824:
3822:
3819:
3817:
3814:
3812:
3810:
3806:
3804:
3801:
3799:
3796:
3794:
3791:
3789:
3788:Guggulsterone
3786:
3784:
3781:
3779:
3776:
3774:
3771:
3769:
3766:
3764:
3761:
3759:
3756:
3754:
3751:
3749:
3746:
3744:
3741:
3739:
3736:
3734:
3731:
3729:
3726:
3724:
3721:
3719:
3716:
3714:
3711:
3709:
3706:
3704:
3701:
3699:
3696:
3694:
3691:
3689:
3686:
3684:
3683:Dicloxacillin
3681:
3679:
3676:
3674:
3671:
3668:
3664:
3661:
3658:
3654:
3651:
3649:
3648:Dexamethasone
3646:
3644:
3641:
3639:
3636:
3634:
3631:
3629:
3626:
3624:
3621:
3619:
3616:
3614:
3611:
3609:
3606:
3604:
3601:
3599:
3596:
3594:
3591:
3589:
3586:
3584:
3583:Cephaloridine
3581:
3579:
3576:
3574:
3571:
3569:
3566:
3564:
3561:
3559:
3556:
3554:
3551:
3549:
3546:
3544:
3541:
3539:
3536:
3534:
3531:
3529:
3526:
3524:
3521:
3519:
3516:
3514:
3511:
3509:
3506:
3504:
3501:
3499:
3496:
3494:
3491:
3489:
3486:
3484:
3481:
3479:
3476:
3473:
3472:
3470:
3465:
3459:
3453:
3450:
3448:
3445:
3443:
3440:
3438:
3435:
3433:
3430:
3428:
3425:
3423:
3420:
3418:
3415:
3413:
3410:
3408:
3405:
3403:
3400:
3398:
3395:
3393:
3390:
3387:
3386:
3383:
3382:Valproic acid
3380:
3378:
3375:
3373:
3370:
3368:
3365:
3363:
3360:
3358:
3355:
3353:
3350:
3348:
3345:
3343:
3342:Phenobarbital
3340:
3338:
3335:
3333:
3330:
3328:
3325:
3323:
3320:
3318:
3315:
3313:
3310:
3308:
3305:
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3300:
3298:
3295:
3293:
3290:
3287:
3283:
3280:
3278:
3275:
3273:
3270:
3268:
3265:
3263:
3260:
3258:
3255:
3253:
3250:
3248:
3245:
3243:
3242:Carbamazepine
3240:
3238:
3235:
3233:
3230:
3228:
3225:
3223:
3220:
3217:
3216:
3214:
3209:
3203:
3199:
3196:
3189:
3184:
3182:
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3170:
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3149:
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3141:
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3126:
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3119:
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3058:
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3053:
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3023:
3020:
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3015:
3013:
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3008:
3005:
3004:
3002:
3000:
2996:
2990:
2987:
2985:
2982:
2980:
2977:
2975:
2972:
2969:
2965:
2962:
2960:
2957:
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2942:
2940:
2937:
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2932:
2930:
2927:
2925:
2922:
2920:
2917:
2915:
2912:
2910:
2907:
2906:
2904:
2902:
2898:
2892:
2889:
2887:
2884:
2883:
2881:
2879:
2875:
2869:
2868:Syrup of figs
2866:
2864:
2861:
2859:
2856:
2854:
2851:
2849:
2846:
2844:
2841:
2839:
2836:
2834:
2833:Dietary fiber
2831:
2830:
2828:
2826:
2822:
2816:
2813:
2811:
2808:
2806:
2803:
2801:
2798:
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2793:
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2786:
2783:
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2692:
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2685:
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2671:
2667:
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2659:
2655:
2651:
2648:(2): 288–93.
2647:
2643:
2635:
2632:
2629:
2625:
2622:
2616:
2613:
2608:
2606:9780122608025
2602:
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2413:9781449665869
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2386:9780323393072
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2361:
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2350:
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2341:
2338:
2333:
2329:
2324:
2319:
2316:(1): 278–82.
2315:
2311:
2307:
2300:
2297:
2292:
2290:9781608317080
2286:
2282:
2281:
2273:
2270:
2265:
2259:
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2248:
2245:
2240:
2236:
2235:GlobalRPH.com
2232:
2226:
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2208:
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2164:
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2141:
2138:
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2072:
2068:
2064:
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2055:
2042:
2038:
2034:
2028:
2025:
2012:
2008:
2004:
1998:
1996:
1992:
1986:
1981:
1977:
1973:
1967:
1964:
1959:
1957:9781890595661
1953:
1949:
1948:
1940:
1937:
1932:
1930:9781449642846
1926:
1922:
1917:
1916:
1908:
1906:
1904:
1900:
1895:
1891:
1887:
1883:
1879:
1875:
1872:(4): 936–71.
1871:
1867:
1860:
1858:
1856:
1854:
1850:
1845:
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1836:
1831:
1827:
1823:
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1662:
1660:
1656:
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1638:
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1607:
1605:
1603:
1601:
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1597:
1593:
1586:
1584:
1578:
1570:
1569:rainbow trout
1562:
1560:
1557:
1550:
1547:). Measuring
1546:
1542:
1538:
1534:
1533:
1528:
1527:
1522:
1521:
1515:
1509:
1508:phytoplankton
1505:
1501:
1500:common limpet
1493:
1489:
1488:
1483:
1482:
1478:
1474:
1466:
1464:
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1458:
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1404:
1400:
1396:
1392:
1384:
1382:
1380:
1376:
1372:
1367:
1365:
1361:
1357:
1356:ethyl acetate
1353:
1349:
1345:
1341:
1337:
1333:
1329:
1325:
1321:
1317:
1313:
1309:
1305:
1301:
1296:
1294:
1293:octyl alcohol
1289:
1287:
1283:
1279:
1275:
1244:
1223:
1215:
1210:
1208:
1201:
1199:
1197:
1196:encapsulation
1194:
1186:
1184:
1182:
1178:
1174:
1170:
1166:
1165:wetting agent
1162:
1158:
1154:
1147:Food additive
1146:
1144:
1142:
1138:
1130:
1128:
1125:
1123:
1118:
1115:
1113:
1104:
1102:
1100:
1096:
1091:
1089:
1084:
1082:
1078:
1074:
1066:
1064:
1062:
1054:
1052:
1049:
1047:
1043:
1039:
1031:
1029:
1026:
1024:
1020:
1019:acute abdomen
1016:
1011:
1009:
1008:breastfeeding
1005:
997:
995:
993:
989:
985:
981:
976:
974:
966:
964:
962:
957:
955:
951:
946:
943:
940:
938:
937:anal fissures
934:
930:
926:
918:
913:
911:
909:
905:
901:
896:
894:
890:
886:
878:
876:
874:
866:
863:It is on the
861:
859:
855:
851:
847:
843:
839:
835:
831:
827:
823:
819:
815:
811:
809:
805:
801:
798:
794:
780:
774:
769:
764:
760:
753:
743:
738:
734:
727:
723:
721:
717:
713:
711:
710:Melting point
707:
704:1.1 g/cm
703:
701:
697:
690:
685:
682:
678:
677:
675:
672:
667:
660:
658:
654:
630:
628:
624:
619:
615:
611:
608:
606:
604:ECHA InfoCard
600:
592:
588:
587:DTXSID8022959
584:
583:
581:
572:
568:
564:
560:
556:
554:
548:
541:
540:ChEMBL1905872
536:
533:
532:ChEMBL1477036
529:
528:
526:
524:
520:
513:
508:
505:
501:
500:
498:
496:
492:
485:
480:
479:
477:
475:
471:
464:
459:
456:
452:
451:
449:
447:
443:
436:
431:
428:
424:
423:
421:
419:
415:
408:
403:
400:
396:
395:
393:
391:
387:
380:
375:
372:
368:
367:
365:
358:
354:
347:
342:
339:
335:
334:
332:
330:
326:
317:
313:
306:
301:
297:
295:
291:
287:
285:
281:
277:
273:
266:
262:
260:
250:
247:
237:
235:
226:
225:
223:
221:
217:
212:
204:
199:
196:
195:
193:
191:
187:
184:
181:
179:
175:
172:
168:
165:
163:
157:
151:
142:
141:
139:
137:
131:
124:
119:
110:
109:
107:
105:
101:
97:
93:
91:
87:
83:
79:
77:
73:
69:
65:
61:
57:
55:
51:
48:Clinical data
46:
39:
34:
26:
22:
4171:
4151:Ketoconazole
4148:Antagonists:
4147:
4121:Troglitazone
4096:Tetracycline
4051:Spiroxatrine
3996:Quingestrone
3991:Progesterone
3976:Pregnenolone
3971:Pregnanolone
3961:Pregnanediol
3956:Prednisolone
3881:Mifepristone
3808:
3783:Griseofulvin
3763:Fenbendazole
3748:Famprofazone
3743:Erythromycin
3738:Epothilone B
3723:Eburnamonine
3618:Clotrimazole
3608:Clofenvinfos
3543:Antimycotics
3474:
3437:Okadaic acid
3389:Antagonists:
3388:
3377:Troglitazone
3312:Mifepristone
3307:Methoxychlor
3302:Griseofulvin
3297:Ellagic acid
3277:Cypermethrin
3267:Clotrimazole
3218:
3138:Prucalopride
3123:Lubiprostone
2756:
2645:
2641:
2634:
2615:
2588:
2558:
2554:
2548:
2536:. Retrieved
2532:
2523:
2511:. Retrieved
2507:the original
2502:
2473:
2467:
2457:
2432:
2428:
2422:
2402:
2395:
2368:
2340:
2313:
2309:
2299:
2279:
2272:
2253:
2247:
2239:the original
2234:
2225:
2206:
2154:
2150:
2140:
2128:. Retrieved
2124:the original
2114:
2097:
2093:
2087:
2075:. Retrieved
2066:
2057:
2045:. Retrieved
2036:
2027:
2015:. Retrieved
2006:
1985:10665/345533
1975:
1966:
1946:
1939:
1914:
1869:
1865:
1817:
1813:
1780:
1739:
1735:
1698:(4): 261–3.
1695:
1691:
1624:. Retrieved
1566:
1530:
1524:
1518:
1516:
1485:
1479:
1475:such as the
1470:
1453:carcinogenic
1450:
1388:
1368:
1312:diethylether
1297:
1290:
1219:
1205:
1190:
1150:
1134:
1126:
1119:
1116:
1108:
1092:
1085:
1081:constipation
1070:
1058:
1055:Interactions
1050:
1035:
1032:Side effects
1027:
1015:appendicitis
1012:
1001:
977:
970:
958:
947:
944:
941:
925:constipation
922:
919:Constipation
907:
897:
892:
882:
862:
817:
812:
807:
803:
799:
792:
791:
407:DBSALT001500
220:Legal status
214:Legal status
104:License data
25:
4136:Zafirlukast
4106:Thiothixene
4086:Terconazole
4036:Simvastatin
3911:Nisoldipine
3906:Nilvadipine
3891:Nicardipine
3861:Metacycline
3688:Dimercaprol
3643:Demecolcine
3603:Clindamycin
3598:Ciglitazone
3548:Artemisinin
3528:Ambrisentan
3432:Nigramide J
3367:Telmisartan
3327:Nicardipine
3237:Benfuracarb
3232:Artemisinin
3133:Plecanatide
3118:Linaclotide
3095:Naldemedine
2891:Mineral oil
2642:Chemosphere
2344:drugs.com:
2157:(1): 12–9.
1477:hermit crab
1473:crustaceans
1461:teratogenic
1403:double bond
1344:isopropanol
1278:carboxylate
1088:gallbladder
992:suspensions
914:Medical use
854:dispersants
850:emulsifiers
664: g·mol
610:100.008.553
303:Identifiers
90:MedlinePlus
63:Other names
54:Trade names
4211:Categories
4116:Tianeptine
4081:Tenylidone
4076:Tacrolimus
4021:Rimexolone
4011:Rifampicin
3951:Plicamycin
3936:Paclitaxel
3921:Omeprazole
3901:Nifedipine
3876:Mevastatin
3871:Metyrapone
3851:Lovastatin
3846:Loratadine
3803:Hyperforin
3793:Haloprogin
3758:Felodipine
3733:Enzacamene
3713:Dronabinol
3678:Diclazuril
3657:prasterone
3613:Chloroxine
3588:Cephradine
3558:Bile acids
3372:Tolnaftate
3337:Permethrin
3322:Nevirapine
3317:Nefazodone
3286:prasterone
3247:Carvedilol
3227:Amiodarone
3198:modulators
3153:Ulimorelin
3085:Bevenopran
2790:Castor oil
2736:cathartics
2538:29 January
2513:24 January
2077:14 January
2047:14 January
2017:14 January
1667:US 2181087
1587:References
1510:have an LD
1328:oleic acid
1308:chloroform
1239:−C(=O)−O−R
1181:carbonated
1177:dispersant
1173:emulsifier
1157:stabilizer
1137:surfactant
1131:Other uses
988:emulsifier
986:and as an
933:hemorrhoid
893:Aerosol OT
669:3D model (
657:Molar mass
512:CHEBI:4674
463:F05Q2T2JA0
455:M7P27195AG
418:ChemSpider
338:10041-19-7
329:CAS Number
312:IUPAC name
248:(GSL, OTC)
178:Drug class
4222:Laxatives
4041:Sirolimus
4031:Ritonavir
4026:Riodipine
4016:Rifaximin
4001:Reserpine
3986:Proadifen
3931:Oxatomide
3886:Nafcillin
3856:Meclizine
3718:Droxidopa
3698:Docetaxel
3623:Colforsin
3573:Bumecaine
3563:Bithionol
3475:Agonists:
3452:T-0901317
3427:Meclizine
3357:Reserpine
3347:Phenytoin
3332:Octicizer
3292:Efavirenz
3219:Agonists:
3148:Tenapanor
3143:Tegaserod
3100:Naloxegol
3080:Axelopran
3075:Alvimopan
3007:Bisacodyl
2919:Laminarid
2914:Lactulose
2858:Sterculia
2843:Ispaghula
2780:Bisoxatin
2775:Bisacodyl
2732:laxatives
2429:Mycologia
1626:11 August
1457:mutagenic
1399:bisulfite
1385:Synthesis
1348:2-butanol
1306:, 1:1 in
1280:ester of
1211:Chemistry
1198:studies.
1161:thickener
1112:bisacodyl
1095:Perfusion
1004:pregnancy
980:lubricant
929:anorectal
889:detergent
842:potassium
826:laxatives
504:CHEBI:534
160:Routes of
134:Pregnancy
82:Monograph
76:Drugs.com
4201:Medicine
4168:See also
4056:SR-12813
3946:Piperine
3926:Orlistat
3896:Nicotine
3768:Fentanyl
3753:Febantel
3728:Ecopipam
3693:Dinaline
3578:Cafestol
3568:Bosentan
3442:PK-11195
3060:Naloxone
3042:Sorbitol
3017:Glycerol
2989:Sorbitol
2968:macrogol
2954:Mannitol
2909:Lactitol
2863:Triticum
2838:Ethulose
2757:Docusate
2670:20579683
2624:Archived
2469:Langmuir
2464:Eastoe J
2462:Nave S,
2449:20983186
2349:Archived
2346:Docusate
2332:16831610
2181:23449608
2106:13362832
2071:Archived
2067:ClinCalc
2041:Archived
2037:ClinCalc
2011:Archived
2007:ClinCalc
1974:(2021).
1894:13869933
1886:15784043
1844:25967924
1789:25520993
1758:30785419
1712:14367076
1650:Archived
1620:Archived
1526:Anabaena
1492:molluscs
1447:Toxicity
1360:furfurol
1340:methanol
1320:glycerol
1046:diarrhea
954:psyllium
908:Doxinate
822:medicine
793:Docusate
552:E number
390:DrugBank
379:23673837
346:577-11-7
190:ATC code
167:By mouth
136:category
123:Docusate
118:DailyMed
30:Docusate
4156:Sesamin
4141:Zeranol
4071:Suramin
3841:LOE-908
3533:AMI-193
3447:S-07662
3362:TCPOBOP
3257:Chrysin
3070:PAMORAs
3012:Dantron
2795:Dantron
2785:Cascara
2689:at the
2650:Bibcode
2435:: 346.
2172:3348737
2130:6 March
1835:6956627
1428:−CH(−SO
1410:−CH=CH−
1332:acetone
1304:ethanol
1193:micelle
1099:jejunum
1061:dantron
1038:stomach
984:tablets
950:placebo
879:History
838:calcium
834:placebo
828:and as
700:Density
627:Formula
399:DB11089
357:PubChem
232::
206:)
200: (
198:A06AA02
149: A
120::
96:a601113
4187:Portal
3663:DHEA-S
3503:AA-861
3111:Others
2999:Enemas
2694:PubMed
2691:N.I.H.
2668:
2603:
2447:
2410:
2383:
2330:
2287:
2260:
2213:
2179:
2169:
2104:
1954:
1927:
1892:
1884:
1842:
1832:
1787:
1756:
1710:
1673:
1397:. The
1362:, and
1324:xylene
1272:. The
1258:−C(−CH
1175:, and
1153:US FDA
1040:pain,
973:earwax
961:opioid
869:
856:, and
733:SMILES
662:421.57
523:ChEMBL
484:D00305
298:3 days
257:
244:
171:rectal
116:
3262:CITCO
1890:S2CID
1810:(PDF)
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