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Palladin

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Further, Salaria et al. have shown that palladin is overexpressed in the non-neoplastic stroma of pancreatic cancer, but only rarely in the cancer cells per se, suggesting that palladin's role in this disease may involve changes in the tumor microenvironmment. More research is clearly required
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Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (2001).
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Palladin was characterised independently by two research groups, first in the lab of Carol Otey (in 2000) and then in the lab of Olli Carpén (in 2001). It is a part of the myotilin-myopalladin-palladin family and may play an important role in modulating the
1302:. The palladin mutation identified in familial pancreatic cancer may be unique to a single North American family, as this same mutation has not been found in any other European or North American populations, respectively, in two other genetic studies. 1270:. In mice, three major isoforms of palladin arise from a single gene. These isoforms contain between three and five copies (depending on the isoform) of an Ig-like domain and between one and two copies of a polyproline domain. 1278:
Palladin's precise biological role is poorly understood, but it has been shown to play a role in cytoskeletal organization, embryonic development, cell motility, scar formation in the skin, and nerve cell development.
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Zogopoulos G, Rothenmund H, Eppel A, Ash C, Akbari MR, Hedley D, Narod SA, Gallinger S (2007). "The P239S palladin variant does not account for a significant fraction of hereditary or early onset pancreas cancer".
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Rönty M, Taivainen A, Moza M, et al. (2005). "Involvement of palladin and alpha-actinin in targeting of the Abl/Arg kinase adaptor ArgBP2 to the actin cytoskeleton".
330: 229: 1433:"Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro" 1900:"Palladin is Overexpressed in the Non-Neoplastic Stroma of Infiltrating Ductal Adenocarcinomas of the Pancreas, but is only Rarely Overexpressed in Neoplastic Cells" 2609:
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization".
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Pogue-Geile KL, Chen R, Bronner MP, Crnogorac-Jurcevic T, Moyes KW, Dowen S, Otey CA, Crispin DA, George RD, Whitcomb DC, Brentnall TA (2006).
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Salaria SN, Illei P, Sharma R, Walter KM, Klein AP, Eshleman JR, Maitra A, Schulick R, Winter J, Ouellette MM, Goggins M, Hruban R (2007).
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Rönty M, Taivainen A, Moza M, et al. (2004). "Molecular analysis of the interaction between palladin and alpha-actinin".
2576:"Isoform-specific regulation of the actin-organizing protein palladin during TGF-beta1-induced myofibroblast differentiation" 1378: 215: 190: 1713:"Identification of palladin isoforms and characterization of an isoform-specific interaction between Lasp-1 and palladin" 1357: 1531:"Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs" 132: 1330: 329: 228: 2025:"Myopalladin, a Novel 145-Kilodalton Sarcomeric Protein with Multiple Roles in Z-Disc and I-Band Protein Assemblies" 1431:
Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Jul 1999).
1982:"Identification of Novel Human Genes Evolutionarily Conserved in Caenorhabditis elegans by Comparative Proteomics" 322: 221: 2721: 2700: 887: 140: 20: 2154:"Pallidin is a component of a multi-protein complex involved in the biogenesis of lysosome-related organelles" 2375:"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" 868: 1951:
King CM, Olive CW, Cardona RA (1975). "Activation of carcinogenic arylhydroxamic acids by human tissues".
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Slater E, Amrillaeva V, Fendrich V, Bartsch D, Earl J, Vitone LJ, Neoptolemos JP, Greenhalf W (2007).
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Disease-causing mutations have also been identified in the two other members of this gene family.
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The eukaryotic cytoskeleton. Palladin is one component of this complex cellular machinery.
1239: 1228: 384: 1754:"Palladin Mutation Causes Familial Pancreatic Cancer and Suggests a New Cancer Mechanism" 2433: 2265: 2212: 2514: 2489: 2049: 2024: 1924: 1831: 1804: 1780: 1753: 1598:
Mykkänen OM, Grönholm M, Rönty M, Lalowski M, Salmikangas P, Suila H, Carpén O (2001).
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In humans, it appears that seven different isoforms exist, some of which arise through
39: 2399: 2374: 2284: 2249: 2231: 2196: 2135: 2110: 2006: 1981: 1659: 1555: 1530: 757: 752: 747: 742: 737: 732: 727: 722: 706: 701: 696: 691: 686: 681: 676: 671: 666: 661: 656: 651: 646: 641: 636: 631: 615: 610: 605: 600: 2786: 2549: 2532: 2170: 2153: 2092: 2067: 1624: 1200: 587: 2638: 2566: 2365: 2187: 144: 2681: 2648:"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" 1884: 1805:"Palladin Mutation Causes Familial Pancreatic Cancer: Absence in European Families" 1216: 402: 181: 2349: 1821: 1770: 168: 2472: 1418:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
123:, CGI-151, CGI151, MYN, PNCA1, SIH002, palladin, cytoskeletal associated protein 2664: 2647: 1249: 485: 2575: 1868: 1712: 1298:, and that palladin is both overexpressed and mutated in an inherited form of 301: 198: 148: 2418:"Generation and annotation of the DNA sequences of human chromosomes 2 and 4" 2490:"Identification of Four Gene Variants Associated with Myocardial Infarction" 2303:"Complete sequencing and characterization of 21,243 full-length human cDNAs" 2274: 1964: 1449: 1432: 1295: 787: 545: 423: 368: 355: 267: 254: 156: 2673: 2630: 2601: 2592: 2558: 2523: 2480: 2451: 2408: 2357: 2328: 2293: 2240: 2221: 2179: 2144: 2101: 2083: 2058: 2015: 1933: 1876: 1840: 1789: 1738: 1677: 1633: 1615: 1564: 1514: 1458: 1313:
mutations cause a form of limb-girdle muscular dystrophy, and mutations in
2040: 1972: 1496: 1169: 1164: 1915: 1292: 1153: 932: 913: 2442: 2417: 2068:"Characterization of Human Palladin, a Microfilament-associated Protein" 1997: 1600:"Characterization of Human Palladin, a Microfilament-associated Protein" 2390: 1546: 1306:
before this protein and its role in neoplasia can be fully understood.
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The palladin/myotilin/myopalladin family of actin-associated scaffolds
89: 85: 2533:"The proline-rich protein palladin is a binding partner for profilin" 1242:, reflecting its localization to architectural elements of the cell. 1137: 809: 2622: 2505: 2319: 2302: 2126: 1654:. International Review of Cytology. Vol. 246. pp. 31–58. 1334: 1248: 1213: 1196: 772: 768: 1314: 1310: 1224: 1220: 1192: 136: 2710: 748:
homophilic cell adhesion via plasma membrane adhesion molecules
2772:: Solution structure of the second ig domain of human palladin 2706: 1582:"Entrez Gene: PALLD palladin, cytoskeletal associated protein" 1288: 2757:: Solution structure of the first ig domain of human palladin 2195:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
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Palladin was named after the Italian Renaissance architect
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Eberle MA, Pfützer R, Pogue-Geile KL, et al. (2002).
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Otey CA, Rachlin A, Moza M, Arneman D, Carpen O (2005).
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Boukhelifa M, Moza M, Johansson T, et al. (2006).
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Gerhard DS, Wagner L, Feingold EA, et al. (2004).
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Shiffman D, Ellis SG, Rowland CM, et al. (2005).
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Hillier LW, Graves TA, Fulton RS, et al. (2005).
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Mykkänen OM, Grönholm M, Rönty M, et al. (2002).
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Bang ML, Mudry RE, McElhinny AS, et al. (2001).
557: 1199:-containing microfilaments that control cell shape, 2574:Rönty MJ, Leivonen SK, Hinz B, et al. (2007). 1086: 1037: 999: 950: 2301:Ota T, Suzuki Y, Nishikawa T, et al. (2004). 1374: 1372: 1370: 1353: 1351: 1349: 2646:Olsen JV, Blagoev B, Gnad F, et al. (2006). 1287:Recently, it has been demonstrated that palladin 339: 238: 2248:Lee SY, Obata Y, Yoshida M, et al. (2003). 1980:Lai CH, Chou CY, Ch'ang LY, et al. (2000). 1645: 1643: 16:Protein-coding gene in the species Homo sapiens 1593: 1591: 1474: 1472: 1470: 1468: 1379:GRCm38: Ensembl release 89: ENSMUSG00000058056 2722: 8: 1358:GRCh38: Ensembl release 89: ENSG00000129116 2729: 2715: 2707: 1317:cause an inherited form of heart disease ( 1034: 947: 783: 583: 380: 279: 176: 74: 2699:at the U.S. National Library of Medicine 2663: 2591: 2548: 2513: 2441: 2398: 2318: 2283: 2273: 2230: 2220: 2169: 2134: 2091: 2048: 2005: 1923: 1830: 1820: 1779: 1769: 1728: 1623: 1554: 1504: 1448: 1576: 1574: 1231:, is expressed ubiquitously in cells of 2744: 1345: 1693: 1683: 29: 2250:"Immunomic analysis of human sarcoma" 344: 305: 300: 243: 202: 197: 7: 616:cell-cell adhesion mediator activity 2152:Moriyama K, Bonifacino JS (2003). 1291:is overexpressed in patients with 1083: 996: 923: 904: 878: 859: 833: 814: 562: 480: 418: 397: 14: 1188:that in humans is encoded by the 2762: 2747: 2550:10.1111/j.1742-4658.2005.05036.x 2171:10.1034/j.1600-0854.2002.30908.x 328: 321: 315: 292: 227: 220: 214: 189: 38: 1479:Parast MM, Otey CA (Sep 2000). 738:actin cytoskeleton organization 1227:, which are expressed only in 546:More reference expression data 1: 2350:10.1016/j.febslet.2004.04.006 1660:10.1016/S0074-7696(05)46002-7 1195:. Palladin is a component of 723:epithelial cell morphogenesis 313: 212: 2254:Proc. Natl. Acad. Sci. U.S.A 2201:Proc. Natl. Acad. Sci. U.S.A 1822:10.1371/journal.pmed.0040164 1771:10.1371/journal.pmed.0030516 1711:Rachlin AS, Otey CA (2006). 601:muscle alpha-actinin binding 2793:Genes on human chromosome 4 2473:10.1016/j.yexcr.2005.06.026 1219:. Palladin, in contrast to 2809: 2665:10.1016/j.cell.2006.09.026 18: 2742: 1869:10.1007/s00439-007-0361-z 1414:"Mouse PubMed Reference:" 1396:"Human PubMed Reference:" 1168: 1163: 1159: 1152: 1136: 1117: 1090: 1061: 1030: 1003: 974: 943: 930: 926: 911: 907: 898: 885: 881: 866: 862: 853: 840: 836: 821: 817: 808: 793: 786: 782: 766: 733:cytoskeleton organization 586: 582: 570: 565: 556: 543: 492: 483: 430: 421: 391: 383: 379: 362: 349: 312: 291: 282: 278: 261: 248: 211: 188: 179: 175: 130: 127: 117: 110: 105: 82: 77: 60: 55: 50: 46: 37: 32: 2701:Medical Subject Headings 1329:PALLD has been shown to 1123:Chr 4: 168.5 – 168.93 Mb 728:keratinocyte development 21:Paladin (disambiguation) 2697:palladin+protein,+human 2275:10.1073/pnas.0437972100 1130:Chr 8: 61.96 – 62.36 Mb 758:dendrite self-avoidance 508:interventricular septum 2593:10.1038/sj.jid.5700427 2222:10.1073/pnas.242603899 2084:10.1091/mbc.12.10.3060 1616:10.1091/mbc.12.10.3060 1319:dilated cardiomyopathy 1254: 504:atrioventricular valve 2041:10.1083/jcb.153.2.413 1965:10.1093/jnci/55.2.285 1497:10.1083/jcb.150.3.643 1450:10.1093/dnares/6.1.63 1252: 462:right coronary artery 1953:J. Natl. Cancer Inst 1916:10.4161/cbt.6.3.3904 1268:alternative splicing 307:Chromosome 8 (mouse) 205:Chromosome 4 (human) 78:List of PDB id codes 51:Available structures 19:For other uses, see 2580:J. Invest. Dermatol 2443:10.1038/nature03466 2434:2005Natur.434..724H 2266:2003PNAS..100.2651L 2213:2002PNAS...9916899M 1998:10.1101/gr.10.5.703 1203:, and contraction. 512:endocardial cushion 2391:10.1101/gr.2596504 1723:(Pt 6): 995–1004. 1547:10.1101/gr.GR1547R 1255: 888:ENSMUSG00000058056 716:Biological process 677:actin cytoskeleton 625:Cellular component 594:Molecular function 442:tail of epididymis 25:Palladin (surname) 2780: 2779: 2494:Am. J. Hum. Genet 2207:(26): 16899–903. 2115:Am. J. Hum. Genet 1904:Cancer Biol. Ther 1730:10.1242/jcs.02825 1300:pancreatic cancer 1259: 1258: 1179: 1178: 1175: 1174: 1148: 1147: 1113: 1112: 1080: 1079: 1026: 1025: 993: 992: 939: 938: 920: 919: 894: 893: 875: 874: 849: 848: 830: 829: 778: 777: 578: 577: 574: 573: 552: 551: 539: 538: 477: 476: 375: 374: 274: 273: 169:PALLD - orthologs 101: 100: 97: 96: 61:Ortholog search: 2800: 2766: 2751: 2731: 2724: 2717: 2708: 2685: 2667: 2642: 2605: 2595: 2570: 2552: 2527: 2517: 2484: 2455: 2445: 2428:(7034): 724–31. 2412: 2402: 2369: 2332: 2322: 2297: 2287: 2277: 2244: 2234: 2224: 2191: 2173: 2148: 2138: 2105: 2095: 2062: 2052: 2019: 2009: 1976: 1938: 1937: 1927: 1895: 1889: 1888: 1851: 1845: 1844: 1834: 1824: 1800: 1794: 1793: 1783: 1773: 1749: 1743: 1742: 1732: 1708: 1702: 1701: 1695: 1691: 1689: 1681: 1647: 1638: 1637: 1627: 1595: 1586: 1585: 1578: 1569: 1568: 1558: 1525: 1519: 1518: 1508: 1476: 1463: 1462: 1452: 1428: 1422: 1421: 1410: 1404: 1403: 1392: 1386: 1376: 1365: 1355: 1245: 1244: 1161: 1160: 1132: 1125: 1108: 1084: 1075: 1035: 1031:RefSeq (protein) 1021: 997: 988: 948: 924: 905: 879: 860: 834: 815: 784: 584: 563: 548: 488: 486:Top expressed in 481: 466:popliteal artery 454:seminal vesicula 426: 424:Top expressed in 419: 398: 381: 371: 358: 347: 332: 325: 319: 308: 296: 280: 270: 257: 246: 231: 224: 218: 207: 193: 177: 171: 122: 115: 92: 75: 69: 48: 47: 42: 30: 2808: 2807: 2803: 2802: 2801: 2799: 2798: 2797: 2783: 2782: 2781: 2776: 2773: 2767: 2758: 2752: 2738: 2735: 2693: 2688: 2645: 2623:10.1038/nbt1240 2617:(10): 1285–92. 2611:Nat. Biotechnol 2608: 2586:(11): 2387–96. 2573: 2530: 2487: 2458: 2415: 2385:(10B): 2121–7. 2372: 2335: 2300: 2247: 2194: 2151: 2108: 2078:(10): 3060–73. 2072:Mol. Biol. Cell 2065: 2022: 1979: 1950: 1946: 1944:Further reading 1941: 1897: 1896: 1892: 1853: 1852: 1848: 1802: 1801: 1797: 1751: 1750: 1746: 1710: 1709: 1705: 1692: 1682: 1670: 1649: 1648: 1641: 1610:(10): 3060–73. 1604:Mol. Biol. Cell 1597: 1596: 1589: 1580: 1579: 1572: 1527: 1526: 1522: 1478: 1477: 1466: 1430: 1429: 1425: 1412: 1411: 1407: 1394: 1393: 1389: 1377: 1368: 1356: 1347: 1343: 1327: 1285: 1283:Disease linkage 1276: 1264: 1240:Andrea Palladio 1229:striated muscle 1209: 1170:View/Edit Mouse 1165:View/Edit Human 1128: 1121: 1118:Location (UCSC) 1104: 1100: 1096: 1092: 1071: 1067: 1063: 1057: 1053: 1049: 1045: 1041: 1017: 1013: 1009: 1005: 984: 980: 976: 970: 966: 962: 958: 954: 869:ENSG00000129116 762: 711: 652:plasma membrane 632:cell projection 620: 606:protein binding 544: 535: 530: 526: 522: 518: 514: 510: 506: 502: 498: 484: 473: 470:tibial arteries 468: 464: 460: 456: 452: 450:visceral pleura 448: 444: 440: 438:right ventricle 436: 422: 366: 353: 345: 335: 334: 333: 326: 306: 283:Gene location ( 265: 252: 244: 234: 233: 232: 225: 203: 180:Gene location ( 131: 118: 111: 84: 62: 28: 17: 12: 11: 5: 2806: 2804: 2796: 2795: 2785: 2784: 2778: 2777: 2775: 2774: 2768: 2761: 2759: 2753: 2746: 2743: 2740: 2739: 2736: 2734: 2733: 2726: 2719: 2711: 2705: 2704: 2692: 2691:External links 2689: 2687: 2686: 2643: 2606: 2571: 2528: 2506:10.1086/491674 2500:(4): 596–605. 2485: 2456: 2413: 2370: 2333: 2320:10.1038/ng1285 2298: 2245: 2192: 2149: 2127:10.1086/339692 2106: 2063: 2020: 1977: 1947: 1945: 1942: 1940: 1939: 1890: 1846: 1795: 1744: 1703: 1694:|journal= 1668: 1639: 1587: 1570: 1520: 1464: 1423: 1405: 1387: 1366: 1344: 1342: 1339: 1326: 1323: 1284: 1281: 1275: 1272: 1263: 1260: 1257: 1256: 1208: 1205: 1177: 1176: 1173: 1172: 1167: 1157: 1156: 1150: 1149: 1146: 1145: 1143: 1141: 1134: 1133: 1126: 1119: 1115: 1114: 1111: 1110: 1088: 1087: 1081: 1078: 1077: 1059: 1058: 1032: 1028: 1027: 1024: 1023: 1001: 1000: 994: 991: 990: 972: 971: 945: 941: 940: 937: 936: 928: 927: 921: 918: 917: 909: 908: 902: 896: 895: 892: 891: 883: 882: 876: 873: 872: 864: 863: 857: 851: 850: 847: 846: 838: 837: 831: 828: 827: 819: 818: 812: 806: 805: 800: 795: 791: 790: 780: 779: 776: 775: 764: 763: 761: 760: 755: 750: 745: 743:cell migration 740: 735: 730: 725: 719: 717: 713: 712: 710: 709: 704: 699: 694: 689: 684: 679: 674: 672:actin filament 669: 664: 659: 654: 649: 644: 639: 637:focal adhesion 634: 628: 626: 622: 621: 619: 618: 613: 608: 603: 597: 595: 591: 590: 580: 579: 576: 575: 572: 571: 568: 567: 560: 554: 553: 550: 549: 541: 540: 537: 536: 534: 533: 532:left ventricle 529: 525: 521: 517: 516:left lung lobe 513: 509: 505: 501: 497: 493: 490: 489: 478: 475: 474: 472: 471: 467: 463: 459: 455: 451: 447: 443: 439: 435: 434:saphenous vein 431: 428: 427: 415: 414: 406: 395: 389: 388: 385:RNA expression 377: 376: 373: 372: 364: 360: 359: 351: 348: 343: 337: 336: 327: 320: 314: 310: 309: 304: 298: 297: 289: 288: 276: 275: 272: 271: 263: 259: 258: 250: 247: 242: 236: 235: 226: 219: 213: 209: 208: 201: 195: 194: 186: 185: 173: 172: 129: 125: 124: 116: 108: 107: 103: 102: 99: 98: 95: 94: 80: 79: 71: 70: 59: 53: 52: 44: 43: 35: 34: 15: 13: 10: 9: 6: 4: 3: 2: 2805: 2794: 2791: 2790: 2788: 2771: 2765: 2760: 2756: 2750: 2745: 2741: 2732: 2727: 2725: 2720: 2718: 2713: 2712: 2709: 2702: 2698: 2695: 2694: 2690: 2683: 2679: 2675: 2671: 2666: 2661: 2658:(3): 635–48. 2657: 2653: 2649: 2644: 2640: 2636: 2632: 2628: 2624: 2620: 2616: 2612: 2607: 2603: 2599: 2594: 2589: 2585: 2581: 2577: 2572: 2568: 2564: 2560: 2556: 2551: 2546: 2542: 2538: 2534: 2529: 2525: 2521: 2516: 2511: 2507: 2503: 2499: 2495: 2491: 2486: 2482: 2478: 2474: 2470: 2466: 2462: 2461:Exp. Cell Res 2457: 2453: 2449: 2444: 2439: 2435: 2431: 2427: 2423: 2419: 2414: 2410: 2406: 2401: 2396: 2392: 2388: 2384: 2380: 2376: 2371: 2367: 2363: 2359: 2355: 2351: 2347: 2344:(1–3): 30–4. 2343: 2339: 2334: 2330: 2326: 2321: 2316: 2312: 2308: 2304: 2299: 2295: 2291: 2286: 2281: 2276: 2271: 2267: 2263: 2260:(5): 2651–6. 2259: 2255: 2251: 2246: 2242: 2238: 2233: 2228: 2223: 2218: 2214: 2210: 2206: 2202: 2198: 2193: 2189: 2185: 2181: 2177: 2172: 2167: 2164:(9): 666–77. 2163: 2159: 2155: 2150: 2146: 2142: 2137: 2132: 2128: 2124: 2121:(4): 1044–8. 2120: 2116: 2112: 2107: 2103: 2099: 2094: 2089: 2085: 2081: 2077: 2073: 2069: 2064: 2060: 2056: 2051: 2046: 2042: 2038: 2035:(2): 413–27. 2034: 2030: 2026: 2021: 2017: 2013: 2008: 2003: 1999: 1995: 1992:(5): 703–13. 1991: 1987: 1983: 1978: 1974: 1970: 1966: 1962: 1958: 1954: 1949: 1948: 1943: 1935: 1931: 1926: 1921: 1917: 1913: 1909: 1905: 1901: 1894: 1891: 1886: 1882: 1878: 1874: 1870: 1866: 1862: 1858: 1850: 1847: 1842: 1838: 1833: 1828: 1823: 1818: 1814: 1810: 1806: 1799: 1796: 1791: 1787: 1782: 1777: 1772: 1767: 1763: 1759: 1755: 1748: 1745: 1740: 1736: 1731: 1726: 1722: 1718: 1714: 1707: 1704: 1699: 1687: 1679: 1675: 1671: 1669:9780123646507 1665: 1661: 1657: 1653: 1646: 1644: 1640: 1635: 1631: 1626: 1621: 1617: 1613: 1609: 1605: 1601: 1594: 1592: 1588: 1583: 1577: 1575: 1571: 1566: 1562: 1557: 1552: 1548: 1544: 1541:(3): 422–35. 1540: 1536: 1532: 1524: 1521: 1516: 1512: 1507: 1502: 1498: 1494: 1491:(3): 643–56. 1490: 1486: 1482: 1475: 1473: 1471: 1469: 1465: 1460: 1456: 1451: 1446: 1442: 1438: 1434: 1427: 1424: 1419: 1415: 1409: 1406: 1401: 1397: 1391: 1388: 1384: 1380: 1375: 1373: 1371: 1367: 1363: 1359: 1354: 1352: 1350: 1346: 1340: 1338: 1336: 1332: 1324: 1322: 1320: 1316: 1312: 1307: 1303: 1301: 1297: 1294: 1290: 1282: 1280: 1273: 1271: 1269: 1261: 1251: 1247: 1246: 1243: 1241: 1236: 1234: 1230: 1226: 1222: 1218: 1215: 1206: 1204: 1202: 1198: 1194: 1191: 1187: 1183: 1171: 1166: 1162: 1158: 1155: 1151: 1144: 1142: 1139: 1135: 1131: 1127: 1124: 1120: 1116: 1109: 1107: 1103: 1099: 1095: 1089: 1085: 1082: 1076: 1074: 1070: 1066: 1060: 1056: 1052: 1048: 1044: 1040: 1036: 1033: 1029: 1022: 1020: 1016: 1012: 1008: 1002: 998: 995: 989: 987: 983: 979: 973: 969: 965: 961: 957: 953: 949: 946: 944:RefSeq (mRNA) 942: 935: 934: 929: 925: 922: 916: 915: 910: 906: 903: 901: 897: 890: 889: 884: 880: 877: 871: 870: 865: 861: 858: 856: 852: 845: 844: 839: 835: 832: 826: 825: 820: 816: 813: 811: 807: 804: 801: 799: 796: 792: 789: 785: 781: 774: 770: 765: 759: 756: 754: 753:axon guidance 751: 749: 746: 744: 741: 739: 736: 734: 731: 729: 726: 724: 721: 720: 718: 715: 714: 708: 705: 703: 700: 698: 697:lamellipodium 695: 693: 690: 688: 685: 683: 680: 678: 675: 673: 670: 668: 665: 663: 662:cell junction 660: 658: 655: 653: 650: 648: 645: 643: 640: 638: 635: 633: 630: 629: 627: 624: 623: 617: 614: 612: 611:actin binding 609: 607: 604: 602: 599: 598: 596: 593: 592: 589: 588:Gene ontology 585: 581: 569: 564: 561: 559: 555: 547: 542: 531: 527: 523: 519: 515: 511: 507: 503: 499: 495: 494: 491: 487: 482: 479: 469: 465: 461: 457: 453: 449: 446:hair follicle 445: 441: 437: 433: 432: 429: 425: 420: 417: 416: 413: 411: 407: 405: 404: 400: 399: 396: 394: 390: 386: 382: 378: 370: 365: 361: 357: 352: 346:8|8 B3.1 342: 338: 331: 324: 318: 311: 303: 299: 295: 290: 286: 281: 277: 269: 264: 260: 256: 251: 241: 237: 230: 223: 217: 210: 206: 200: 196: 192: 187: 183: 178: 174: 170: 166: 162: 158: 154: 150: 146: 142: 138: 134: 126: 121: 114: 109: 104: 93: 91: 87: 81: 76: 73: 72: 68: 65: 58: 54: 49: 45: 41: 36: 31: 26: 22: 2769: 2754: 2655: 2651: 2614: 2610: 2583: 2579: 2543:(1): 26–33. 2540: 2536: 2497: 2493: 2467:(1): 88–98. 2464: 2460: 2425: 2421: 2382: 2378: 2341: 2337: 2310: 2306: 2257: 2253: 2204: 2200: 2161: 2157: 2118: 2114: 2075: 2071: 2032: 2029:J. Cell Biol 2028: 1989: 1985: 1959:(2): 285–7. 1956: 1952: 1910:(3): 324–8. 1907: 1903: 1893: 1863:(5): 635–7. 1860: 1856: 1849: 1812: 1808: 1798: 1764:(12): e516. 1761: 1757: 1747: 1720: 1716: 1706: 1651: 1607: 1603: 1538: 1534: 1523: 1488: 1484: 1443:(1): 63–70. 1440: 1436: 1426: 1417: 1408: 1399: 1390: 1328: 1325:Interactions 1308: 1304: 1286: 1277: 1265: 1237: 1217:cytoskeleton 1210: 1189: 1181: 1180: 1106:NP_001280703 1102:NP_001280702 1098:NP_001280701 1094:NP_001074859 1091: 1073:NP_001354499 1069:NP_001354498 1065:NP_001354497 1062: 1055:NP_001354496 1047:NP_001159582 1043:NP_001159581 1039:NP_001159580 1019:NM_001293774 1015:NM_001293773 1011:NM_001293772 1007:NM_001081390 1004: 986:NM_001367570 982:NM_001367569 978:NM_001367568 975: 968:NM_001367567 960:NM_001166110 956:NM_001166109 952:NM_001166108 931: 912: 886: 867: 841: 822: 802: 797: 687:cytoskeleton 408: 401: 266:168,928,457 253:168,497,052 128:External IDs 83: 2737:PDB gallery 2313:(1): 40–5. 1815:(4): e164. 1717:J. Cell Sci 1485:J Cell Biol 1315:myopalladin 1233:mesenchymal 1225:myopalladin 642:growth cone 367:62,355,724 354:61,964,467 106:Identifiers 2379:Genome Res 2307:Nat. Genet 1986:Genome Res 1857:Hum. Genet 1584:. nih.gov. 1535:Genome Res 1385:, May 2017 1364:, May 2017 1341:References 1293:pancreatic 667:Z discdkac 496:belly cord 458:myometrium 412:(ortholog) 149:HomoloGene 2338:FEBS Lett 1696:ignored ( 1686:cite book 1296:neoplasia 1207:Discovery 1051:NP_057165 964:NM_016081 788:Orthologs 702:cytoplasm 520:ventricle 157:GeneCards 2787:Category 2674:17081983 2639:14294292 2631:16964243 2602:16794588 2567:21207885 2559:16367745 2524:16175505 2481:16125169 2452:15815621 2409:15489334 2366:86151740 2358:15147863 2329:14702039 2294:12601173 2241:12477932 2188:29888859 2180:12191018 2145:11870593 2102:11598191 2059:11309420 2016:10810093 1934:17404500 1877:17415588 1841:17455999 1809:PLOS Med 1790:17194196 1758:PLOS Med 1739:16492705 1678:16164966 1634:11598191 1565:11230166 1515:10931874 1459:10231032 1381:– 1360:– 1331:interact 1311:Myotilin 1274:Function 1262:Isoforms 1235:origin. 1221:myotilin 1201:adhesion 1182:Palladin 1154:Wikidata 767:Sources: 682:podosome 528:gastrula 2682:7827573 2515:1275608 2430:Bibcode 2262:Bibcode 2209:Bibcode 2158:Traffic 2050:2169455 1973:1159819 1925:3144721 1885:2445261 1832:1855695 1781:1751121 1506:2175193 1437:DNA Res 1383:Ensembl 1362:Ensembl 1186:protein 900:UniProt 855:Ensembl 794:Species 773:QuickGO 707:cytosol 692:nucleus 387:pattern 145:1919583 113:Aliases 2703:(MeSH) 2680:  2672:  2637:  2629:  2600:  2565:  2557:  2537:FEBS J 2522:  2512:  2479:  2450:  2422:Nature 2407:  2400:528928 2397:  2364:  2356:  2327:  2292:  2285:151395 2282:  2239:  2232:139241 2229:  2186:  2178:  2143:  2136:379100 2133:  2100:  2090:  2057:  2047:  2014:  2007:310876 2004:  1971:  1932:  1922:  1883:  1875:  1839:  1829:  1788:  1778:  1737:  1676:  1666:  1632:  1622:  1563:  1556:311072 1553:  1513:  1503:  1457:  1140:search 1138:PubMed 933:Q9ET54 914:Q8WX93 810:Entrez 647:ruffle 558:BioGPS 524:uterus 500:atrium 245:4q32.3 137:608092 2678:S2CID 2635:S2CID 2563:S2CID 2362:S2CID 2184:S2CID 2093:60155 1881:S2CID 1625:60155 1333:with 1214:actin 1197:actin 1190:PALLD 1184:is a 843:72333 824:23022 803:Mouse 798:Human 769:Amigo 410:Mouse 403:Human 350:Start 285:Mouse 249:Start 182:Human 161:PALLD 153:75052 120:PALLD 33:PALLD 2770:2dm3 2755:2dm2 2670:PMID 2652:Cell 2627:PMID 2598:PMID 2555:PMID 2520:PMID 2477:PMID 2448:PMID 2405:PMID 2354:PMID 2325:PMID 2290:PMID 2237:PMID 2176:PMID 2141:PMID 2098:PMID 2055:PMID 2012:PMID 1969:PMID 1930:PMID 1873:PMID 1837:PMID 1786:PMID 1735:PMID 1698:help 1674:PMID 1664:ISBN 1630:PMID 1561:PMID 1511:PMID 1455:PMID 1223:and 1193:gene 657:axon 393:Bgee 341:Band 302:Chr. 240:Band 199:Chr. 133:OMIM 90:2DM3 86:2DM2 67:RCSB 64:PDBe 23:and 2660:doi 2656:127 2619:doi 2588:doi 2584:126 2545:doi 2541:273 2510:PMC 2502:doi 2469:doi 2465:310 2438:doi 2426:434 2395:PMC 2387:doi 2346:doi 2342:566 2315:doi 2280:PMC 2270:doi 2258:100 2227:PMC 2217:doi 2166:doi 2131:PMC 2123:doi 2088:PMC 2080:doi 2045:PMC 2037:doi 2033:153 2002:PMC 1994:doi 1961:doi 1920:PMC 1912:doi 1865:doi 1861:121 1827:PMC 1817:doi 1776:PMC 1766:doi 1725:doi 1721:119 1656:doi 1620:PMC 1612:doi 1551:PMC 1543:doi 1501:PMC 1493:doi 1489:150 1445:doi 1335:EZR 1321:). 1289:RNA 566:n/a 363:End 262:End 165:OMA 141:MGI 57:PDB 2789:: 2676:. 2668:. 2654:. 2650:. 2633:. 2625:. 2615:24 2613:. 2596:. 2582:. 2578:. 2561:. 2553:. 2539:. 2535:. 2518:. 2508:. 2498:77 2496:. 2492:. 2475:. 2463:. 2446:. 2436:. 2424:. 2420:. 2403:. 2393:. 2383:14 2381:. 2377:. 2360:. 2352:. 2340:. 2323:. 2311:36 2309:. 2305:. 2288:. 2278:. 2268:. 2256:. 2252:. 2235:. 2225:. 2215:. 2205:99 2203:. 2199:. 2182:. 2174:. 2160:. 2156:. 2139:. 2129:. 2119:70 2117:. 2113:. 2096:. 2086:. 2076:12 2074:. 2070:. 2053:. 2043:. 2031:. 2027:. 2010:. 2000:. 1990:10 1988:. 1984:. 1967:. 1957:55 1955:. 1928:. 1918:. 1906:. 1902:. 1879:. 1871:. 1859:. 1835:. 1825:. 1811:. 1807:. 1784:. 1774:. 1760:. 1756:. 1733:. 1719:. 1715:. 1690:: 1688:}} 1684:{{ 1672:. 1662:. 1642:^ 1628:. 1618:. 1608:12 1606:. 1602:. 1590:^ 1573:^ 1559:. 1549:. 1539:11 1537:. 1533:. 1509:. 1499:. 1487:. 1483:. 1467:^ 1453:. 1439:. 1435:. 1416:. 1398:. 1369:^ 1348:^ 1337:. 771:/ 369:bp 356:bp 268:bp 255:bp 163:; 159:: 155:; 151:: 147:; 143:: 139:; 135:: 88:, 2730:e 2723:t 2716:v 2684:. 2662:: 2641:. 2621:: 2604:. 2590:: 2569:. 2547:: 2526:. 2504:: 2483:. 2471:: 2454:. 2440:: 2432:: 2411:. 2389:: 2368:. 2348:: 2331:. 2317:: 2296:. 2272:: 2264:: 2243:. 2219:: 2211:: 2190:. 2168:: 2162:3 2147:. 2125:: 2104:. 2082:: 2061:. 2039:: 2018:. 1996:: 1975:. 1963:: 1936:. 1914:: 1908:6 1887:. 1867:: 1843:. 1819:: 1813:4 1792:. 1768:: 1762:3 1741:. 1727:: 1700:) 1680:. 1658:: 1636:. 1614:: 1567:. 1545:: 1517:. 1495:: 1461:. 1447:: 1441:6 1420:. 1402:. 287:) 184:) 167:: 27:.

Index

Paladin (disambiguation)
Palladin (surname)

PDB
PDBe
RCSB
2DM2
2DM3
Aliases
PALLD
OMIM
608092
MGI
1919583
HomoloGene
75052
GeneCards
PALLD
OMA
PALLD - orthologs
Human
Chromosome 4 (human)
Chr.
Chromosome 4 (human)
Chromosome 4 (human)
Genomic location for PALLD
Genomic location for PALLD
Band
bp
bp

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