1025:), low blood sugar, reduced amount of potassium and sodium, depression, hallucinations, anxiety, insomnia, agitation, confusion, convulsions, fainting, tremor, weakness, tingling, sleepiness, dizziness, bleeding retina, irregular heart beats, slow or fast heart beats, low blood pressure, inflamed veins, acute respiratory distress syndrome, pulmonary edema, inflamed lips, swollen face, stomach upset, constipation, gingivitis, jaundice, hair loss, flaky skin, itchiness, red skin, back pain, chest pain, and chills.
654:
631:
40:
31:
2639:
1158:
As of July 2017, the medication is marketed under the following names worldwide: Cantex, Pinup, Vedilozin, Vfend, Vodask, Volric, Voramol, Voriconazol, Voriconazole, Voriconazolum, Voricostad, Vorikonazol, Voritek, Voriz, Vornal, and
Vosicaz.
1202:
1782:
1002:
Additionally, very common adverse effects, occurring in more than 10% of people, include peripheral edema, headaches, trouble breathing, diarrhea, vomiting, abdominal pain, nausea, rashes, and fever.
273:
1552:
Herbrecht R, Denning DW, Patterson TF, Bennett JE, Greene RE, Oestmann JW, et al. (August 2002). "Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis".
1141:
Pfizer brought the drug to market as Vfend. A generic version of the tablet form of voriconazole was introduced in the US in 2011 after Pfizer and Mylan settled litigation under the
2704:
1176:
1145:; a generic version of the injectable form was introduced in 2012. In Europe patent protection expired in 2011 and pediatric administrative exclusivity expired in Europe in 2016.
228:
2669:
951:
No dose adjustment is necessary for renal impairment or advanced age, but children seem to clear voriconazole faster than adults and drug levels may need monitoring.
726:
1840:
122:
740:
1268:"Vfend- voriconazole tablet, film coated Vfend- voriconazole injection, powder, lyophilized, for solution Vfend- voriconazole powder, for suspension"
1612:"Interim Treatment Guidance for Central Nervous System and Parameningeal Infections Associated with Injection of Contaminated Steroid Products"
1597:
1494:
2593:
1877:
873:
2679:
1339:
1005:
Common adverse effects, occurring in between 1 and 10% of people, include sinus infections, low numbers of white and red blood cells (
768:
InChI=1S/C16H14F3N5O/c1-10(15-14(19)5-20-7-22-15)16(25,6-24-9-21-8-23-24)12-3-2-11(17)4-13(12)18/h2-5,7-10,25H,6H2,1H3/t10-,16+/m0/s1
1366:
760:
98:
1447:"Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America"
1267:
945:
926:
It is also the recommended treatment for the CNS fungal infections transmitted by epidural injection of contaminated steroids.
416:
258:
154:
2360:
2699:
1927:
2629:
988:
2684:
1733:"Voriconazole-associated periostitis: Pathophysiology, risk factors, clinical manifestations, diagnosis, and management"
530:
173:
2610:
610:
1040:, voriconazole interacts with many drugs. Voriconazole should not be used in conjunction with many drugs (including
2694:
2659:
2428:
2398:
1870:
1382:
984:
2674:
2293:
913:
2598:
2528:
1064:
alkaloids) and dose adjustments and/or monitoring should be done when coadministered with others (including
960:
937:
It is toxic to the fetus; pregnant women should not take it and women taking it should not become pregnant.
210:
649:
2565:
2212:
909:
872:
Voriconazole was patented in 1990 and approved for medical use in the United States in 2002. It is on the
337:
2664:
1591:
1488:
803:
599:
39:
2689:
1863:
1445:
Patterson TF, Thompson GR, Denning DW, Fishman JA, Hadley S, Herbrecht R, et al. (August 2016).
847:
385:
2355:
2171:
843:
626:
445:
221:
217:
948:
should not take this drug. It should be used with caution in people with arrhythmias or long QT.
2518:
2488:
2483:
992:
819:
184:
2379:
1844:
1764:
1713:
1664:
1633:
Smith J, Safdar N, Knasinski V, Simmons W, Bhavnani SM, Ambrose PG, et al. (April 2006).
1579:
1534:
1476:
1362:
1356:
1335:
1329:
1177:"Prescription medicines: registration of new generic medicines and biosimilar medicines, 2017"
1105:
807:
579:
297:
285:
112:
2523:
2473:
1754:
1744:
1703:
1695:
1654:
1646:
1569:
1561:
1524:
1466:
1458:
1390:
1142:
1014:
964:
917:
905:
666:
454:
319:
57:
539:
519:
2643:
2105:
2095:
1611:
1230:
1130:
1037:
1006:
929:
It can be taken by mouth or given in a doctor's office or clinic by intravenous infusion.
347:
327:
853:
Common side effects include vision problems, nausea, abdominal pain, rash, headache, and
1803:
653:
630:
2604:
2535:
2478:
2448:
2433:
2201:
2090:
1759:
1732:
1708:
1683:
1659:
1634:
1471:
1446:
854:
823:
30:
1133:
of 96%, allowing patients to be switched between intravenous and oral administration.
2653:
2438:
2334:
2308:
2115:
2067:
2033:
1988:
1958:
1207:
1053:
980:
968:
885:
866:
827:
811:
642:
146:
1650:
1306:
132:
2560:
2545:
2458:
2388:
2304:
2138:
2133:
2120:
2110:
2100:
2018:
2008:
2003:
1993:
1978:
1968:
1953:
1894:
1890:
1113:
1010:
976:
972:
894:
832:
241:
236:
1423:
479:
1529:
1512:
979:
damage; trouble with vision; and adverse effects in skin including damage due to
2579:
2540:
2498:
2468:
2369:
2313:
2249:
2237:
2085:
2077:
2072:
2043:
2038:
2028:
2023:
1998:
1973:
1830:
1073:
1065:
996:
889:
815:
140:
1834:
1699:
2569:
2550:
2513:
2508:
2493:
2463:
2443:
2408:
2328:
2323:
2318:
2279:
2258:
2223:
2176:
2013:
1963:
1948:
1912:
1886:
1093:
1089:
1081:
1077:
1045:
1018:
702:
510:
371:
22:
2555:
2503:
2232:
2191:
2157:
1983:
1939:
1855:
1682:
Stefan S, Altork N, Alzedaneen Y, Whitlatch H, Munir KM (1 September 2022).
1101:
1097:
1085:
1057:
1049:
1041:
941:
858:
398:
126:
1848:
1768:
1749:
1717:
1668:
1583:
1538:
1480:
1387:
World Health
Organization model list of essential medicines: 21st list 2019
923:
It is also used to prevent fungal infection in people as they undergo BMT.
865:
family of medications. It works by affecting fungal metabolism and fungal
2453:
2196:
2148:
2058:
1565:
1462:
1069:
900:
862:
838:
490:
168:
1513:"Complications of hematopoietic stem transplantation: Fungal infections"
1395:
499:
2574:
2186:
1574:
1109:
465:
356:
1022:
590:
364:
360:
1331:
Kendig and
Chernick's Disorders of the Respiratory Tract in Children
559:
1923:
1061:
1034:
725:
716:
570:
352:
550:
303:
1859:
291:
163:
1833:. In Pratt VM, McLeod HL, Rubinstein WS, et al. (eds.).
63:
615:
267:
195:
87:
81:
75:
66:
1399:. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
432:)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1
280:
874:
785:
2627:
991:; in long-term use there is a warning of the risk of
99:
84:
78:
72:
90:
60:
2421:
2397:
2378:
2354:
2347:
2292:
2271:
2248:
2222:
2211:
2170:
2147:
2057:
1938:
1922:
1911:
1902:
1309:. The American Society of Health-System Pharmacists
714:
701:
665:
660:
641:
609:
589:
569:
549:
529:
509:
489:
464:
444:
407:
397:
384:
370:
346:
336:
326:
318:
257:
252:
227:
209:
183:
153:
139:
121:
111:
69:
51:
46:
1426:. UK Electronic Medicines Compendium. January 2017
1262:
1260:
1258:
1256:
1254:
1252:
959:The labels carry several warnings of the risk of
908:patients, including people undergoing allogeneic
1731:Guarascio AJ, Bhanot N, Min Z (September 2021).
1088:). Voriconazole may be safely administered with
478:
453:
2705:World Health Organization essential medicines
1871:
1841:National Center for Biotechnology Information
1418:
1416:
1414:
1412:
1410:
1408:
1406:
861:may result in harm to the baby. It is in the
855:seeing or hearing things that are not present
8:
1614:. Centers for Disease Control and Prevention
1506:
1504:
1129:Voriconazole is well absorbed orally with a
172:
21:
1831:"Voriconazole Therapy and CYP2C19 Genotype"
940:People who have hereditary intolerance for
380:-oxide (major; minimal antifungal activity)
311:In general: ℞ (Prescription only)
2351:
2219:
1935:
1919:
1908:
1878:
1864:
1856:
1684:"Voriconazole-Induced Diffuse Periostitis"
1635:"Voriconazole therapeutic drug monitoring"
1511:Omrani AS, Almaghrabi RS (December 2017).
1328:Kendig EL, Wilmott RW, Chernick V (2012).
1301:
1299:
1297:
1295:
1293:
1291:
1289:
652:
629:
518:
38:
29:
1758:
1748:
1707:
1658:
1573:
1528:
1517:Hematology/Oncology and Stem Cell Therapy
1470:
1394:
1334:. Elsevier Health Sciences. p. 539.
538:
1804:"Voriconazole international brand names"
1203:"Product monograph brand safety updates"
2634:
1783:"Vfend loses its paediatric protection"
1168:
884:Voriconazole is used to treat invasive
765:
745:
625:
498:
421:
145:
1589:
1486:
1361:. John Wiley & Sons. p. 503.
1181:Therapeutic Goods Administration (TGA)
643:
20:
2670:Lanosterol 14α-demethylase inhibitors
1639:Antimicrobial Agents and Chemotherapy
1389:. Geneva: World Health Organization.
748:Fc1cncnc1((O)(c2ccc(F)cc2F)Cn3ncnc3)C
598:
578:
131:
7:
240:
1554:The New England Journal of Medicine
558:
469:
1596:: CS1 maint: overridden setting (
1493:: CS1 maint: overridden setting (
14:
2637:
1737:World Journal of Transplantation
999:especially in elderly patients.
892:and fungal infections caused by
689:
683:
677:
359:(significant involvement), also
56:
2361:thymidylate synthase inhibitors
1651:10.1128/AAC.50.4.1570-1572.2006
1355:Fischer J, Ganellin CR (2006).
1235:European Medicines Agency (EMA)
946:glucose-galactose malabsorption
944:, Lapp lactase deficiency, or
773:Key:BCEHBSKCWLPMDN-MGPLVRAMSA-N
695:
671:
436:-1,2,4-triazol-1-yl)butan-2-ol
1:
1358:Analogue-based Drug Discovery
1790:IMS Health Generics Bulletin
1530:10.1016/j.hemonc.2017.05.013
1451:Clinical Infectious Diseases
904:species, which may occur in
798:, sold under the brand name
2721:
1836:Medical Genetics Summaries
1700:10.1016/j.aace.2022.05.001
1688:AACE Clinical Case Reports
806:used to treat a number of
661:Chemical and physical data
16:Triazole antifungical drug
2680:Drugs developed by Pfizer
2588:
2429:bromochlorosalicylanilide
2399:Aminoacyl tRNA synthetase
1424:"Vfend tablet and powder"
1383:World Health Organization
985:squamous cell skin cancer
781:
756:
736:
412:
37:
28:
1829:Dean L (December 2019).
989:Stevens–Johnson syndrome
961:injection site reactions
2213:Squalene monooxygenase
2050:Systemic: ketoconazole
1750:10.5500/wjt.v11.i9.356
910:bone marrow transplant
2241:Systemic: terbinafine
1033:Being metabolized by
848:injection into a vein
804:antifungal medication
2700:Triazole antifungals
2529:Whitfield's ointment
2356:Pyrimidine analogues
2172:Polyene antimycotics
1566:10.1056/NEJMoa020191
830:, and infections by
802:among others, is an
2685:Phenylethanolamines
1274:. 16 September 2020
1149:Society and culture
914:hematologic cancers
276:(Prescription only)
25:
2615:Never to phase III
2519:tribromometacresol
2489:sodium thiosulfate
2484:selenium disulfide
2380:Mitotic inhibitors
1463:10.1093/cid/ciw326
842:. It can be taken
820:coccidioidomycosis
2695:Tertiary alcohols
2660:CYP3A4 inhibitors
2625:
2624:
2417:
2416:
2343:
2342:
2294:β-glucan synthase
2288:
2287:
2267:
2266:
2166:
2165:
933:Contraindications
918:organ transplants
912:(BMT), who have
906:immunocompromised
808:fungal infections
793:
792:
727:Interactive image
611:CompTox Dashboard
307:
295:
283:
271:
199:
166:
2712:
2642:
2641:
2640:
2633:
2524:undecylenic acid
2474:potassium iodide
2352:
2220:
1936:
1920:
1909:
1880:
1873:
1866:
1857:
1852:
1816:
1815:
1813:
1811:
1800:
1794:
1793:
1787:
1779:
1773:
1772:
1762:
1752:
1728:
1722:
1721:
1711:
1679:
1673:
1672:
1662:
1645:(4): 1570–1572.
1630:
1624:
1623:
1621:
1619:
1608:
1602:
1601:
1595:
1587:
1577:
1549:
1543:
1542:
1532:
1508:
1499:
1498:
1492:
1484:
1474:
1442:
1436:
1435:
1433:
1431:
1420:
1401:
1400:
1398:
1379:
1373:
1372:
1352:
1346:
1345:
1325:
1319:
1318:
1316:
1314:
1303:
1284:
1283:
1281:
1279:
1264:
1247:
1246:
1244:
1242:
1227:
1221:
1220:
1218:
1216:
1199:
1193:
1192:
1190:
1188:
1173:
1143:Hatch-Waxman Act
1125:Pharmacokinetics
1015:thrombocytopenia
965:hypersensitivity
810:. This includes
789:
788:
729:
709:
697:
691:
685:
679:
673:
656:
645:
634:
633:
619:
617:
602:
582:
562:
542:
522:
502:
482:
472:
471:
457:
389:
305:
302:
293:
290:
282:
279:
269:
266:
244:
197:
194:
176:
165:
162:
149:
135:
103:
97:
96:
93:
92:
89:
86:
83:
80:
77:
74:
71:
68:
65:
62:
42:
33:
26:
24:
2720:
2719:
2715:
2714:
2713:
2711:
2710:
2709:
2675:Organofluorides
2650:
2649:
2648:
2638:
2636:
2628:
2626:
2621:
2620:
2605:Clinical trials
2584:
2413:
2393:
2374:
2359:
2339:
2296:
2284:
2263:
2244:
2240:
2215:
2207:
2199:
2174:
2162:
2143:
2096:fosravuconazole
2053:
1929:
1928:lanosterol 14α-
1915:
1904:
1898:
1884:
1828:
1825:
1823:Further reading
1820:
1819:
1809:
1807:
1802:
1801:
1797:
1792:. 22 July 2016.
1785:
1781:
1780:
1776:
1730:
1729:
1725:
1681:
1680:
1676:
1632:
1631:
1627:
1617:
1615:
1610:
1609:
1605:
1588:
1551:
1550:
1546:
1510:
1509:
1502:
1485:
1444:
1443:
1439:
1429:
1427:
1422:
1421:
1404:
1381:
1380:
1376:
1369:
1354:
1353:
1349:
1342:
1327:
1326:
1322:
1312:
1310:
1305:
1304:
1287:
1277:
1275:
1266:
1265:
1250:
1240:
1238:
1237:. 19 March 2002
1229:
1228:
1224:
1214:
1212:
1201:
1200:
1196:
1186:
1184:
1175:
1174:
1170:
1165:
1156:
1151:
1139:
1131:bioavailability
1127:
1122:
1038:cytochrome P450
1031:
1007:agranulocytosis
957:
935:
916:or who undergo
882:
784:
782:
777:
774:
769:
764:
763:
752:
749:
744:
743:
732:
707:
694:
688:
682:
676:
637:
613:
605:
585:
565:
545:
525:
505:
485:
468:
460:
440:
437:
420:
419:
387:
338:Protein binding
328:Bioavailability
320:Pharmacokinetic
314:
248:
212:
205:
186:
179:
101:
59:
55:
17:
12:
11:
5:
2718:
2716:
2708:
2707:
2702:
2697:
2692:
2687:
2682:
2677:
2672:
2667:
2662:
2652:
2651:
2647:
2646:
2623:
2622:
2619:
2618:
2617:
2616:
2613:
2602:
2596:
2590:
2589:
2586:
2585:
2583:
2582:
2577:
2572:
2563:
2558:
2553:
2548:
2543:
2538:
2536:citronella oil
2532:
2531:
2526:
2521:
2516:
2511:
2506:
2501:
2496:
2491:
2486:
2481:
2479:salicylic acid
2476:
2471:
2466:
2461:
2456:
2451:
2449:crystal violet
2446:
2441:
2436:
2434:chlorophetanol
2431:
2425:
2423:
2419:
2418:
2415:
2414:
2412:
2411:
2404:
2402:
2395:
2394:
2392:
2391:
2384:
2382:
2376:
2375:
2373:
2372:
2365:
2363:
2349:
2345:
2344:
2341:
2340:
2338:
2337:
2332:
2326:
2321:
2316:
2311:
2300:
2298:
2290:
2289:
2286:
2285:
2283:
2282:
2275:
2273:
2269:
2268:
2265:
2264:
2262:
2261:
2254:
2252:
2246:
2245:
2243:
2242:
2235:
2228:
2226:
2217:
2209:
2208:
2206:
2205:
2202:amphotericin B
2194:
2189:
2182:
2180:
2168:
2167:
2164:
2163:
2161:
2160:
2153:
2151:
2145:
2144:
2142:
2141:
2136:
2129:
2128:
2123:
2118:
2113:
2108:
2103:
2098:
2093:
2091:fosfluconazole
2088:
2081:
2080:
2075:
2070:
2063:
2061:
2055:
2054:
2052:
2051:
2047:
2046:
2041:
2036:
2031:
2026:
2021:
2016:
2011:
2006:
2001:
1996:
1991:
1986:
1981:
1976:
1971:
1966:
1961:
1956:
1951:
1944:
1942:
1933:
1917:
1906:
1900:
1899:
1885:
1883:
1882:
1875:
1868:
1860:
1854:
1853:
1824:
1821:
1818:
1817:
1795:
1774:
1743:(9): 356–371.
1723:
1694:(5): 191–193.
1674:
1625:
1603:
1560:(6): 408–415.
1544:
1523:(4): 239–244.
1500:
1437:
1402:
1374:
1367:
1347:
1341:978-1437719840
1340:
1320:
1307:"Voriconazole"
1285:
1248:
1222:
1194:
1183:. 21 June 2022
1167:
1166:
1164:
1161:
1155:
1152:
1150:
1147:
1138:
1135:
1126:
1123:
1121:
1118:
1030:
1027:
993:bone fluorosis
956:
953:
934:
931:
881:
878:
867:cell membranes
824:histoplasmosis
791:
790:
779:
778:
776:
775:
772:
770:
767:
759:
758:
757:
754:
753:
751:
750:
747:
739:
738:
737:
734:
733:
731:
730:
722:
720:
712:
711:
705:
699:
698:
692:
686:
680:
674:
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450:
448:
442:
441:
439:
438:
423:
415:
414:
413:
410:
409:
405:
404:
403:Urine (80–83%)
401:
395:
394:
393:Dose-dependent
391:
382:
381:
374:
368:
367:
350:
344:
343:
340:
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2336:
2335:ibrexafungerp
2333:
2330:
2327:
2325:
2322:
2320:
2317:
2315:
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2309:anidulafungin
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2305:echinocandins
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2277:
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2146:
2140:
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2130:
2127:
2124:
2122:
2119:
2117:
2116:oteseconazole
2114:
2112:
2109:
2107:
2106:isavuconazole
2104:
2102:
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2097:
2094:
2092:
2089:
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2069:
2068:efinaconazole
2065:
2064:
2062:
2060:
2056:
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2048:
2045:
2042:
2040:
2037:
2035:
2034:sertaconazole
2032:
2030:
2027:
2025:
2022:
2020:
2017:
2015:
2012:
2010:
2007:
2005:
2002:
2000:
1997:
1995:
1992:
1990:
1989:fenticonazole
1987:
1985:
1982:
1980:
1977:
1975:
1972:
1970:
1967:
1965:
1962:
1960:
1959:chlormidazole
1957:
1955:
1952:
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1946:
1945:
1943:
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1106:mycophenolate
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1063:
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1054:carbamazepine
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981:phototoxicity
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924:
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911:
907:
903:
902:
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886:aspergillosis
879:
877:
875:
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868:
864:
860:
857:. Use during
856:
851:
849:
845:
841:
840:
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829:
828:penicilliosis
825:
821:
817:
813:
812:aspergillosis
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805:
801:
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644:ECHA InfoCard
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476:
474:
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435:
431:
427:
422:
418:
411:
406:
402:
400:
396:
392:
390:
383:
379:
376:Voriconazole
375:
373:
369:
366:
362:
358:
354:
351:
349:
345:
341:
339:
335:
331:
329:
325:
321:
317:
310:
308: Rx-only
301:
299:
289:
287:
278:
275:
265:
264:
262:
260:
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251:
243:
238:
235:
234:
232:
230:
226:
223:
219:
216:
214:
208:
202:
193:
192:
190:
188:
182:
175:
170:
161:
160:
158:
156:
152:
148:
144:
142:
138:
134:
130:
128:
124:
120:
117:Vfend, others
116:
114:
110:
106:
105:
95:
54:
52:Pronunciation
50:
47:Clinical data
45:
41:
36:
32:
27:
19:
2665:Fluoroarenes
2561:tea tree oil
2546:lemon myrtle
2459:ethylparaben
2389:griseofulvin
2250:Benzylamines
2139:ravuconazole
2134:albaconazole
2126:voriconazole
2125:
2121:posaconazole
2111:itraconazole
2101:hexaconazole
2019:neticonazole
2009:luliconazole
2004:ketoconazole
1994:flutrimazole
1979:eberconazole
1969:clotrimazole
1954:butoconazole
1835:
1808:. Retrieved
1798:
1789:
1777:
1740:
1736:
1726:
1691:
1687:
1677:
1642:
1638:
1628:
1616:. Retrieved
1606:
1592:cite journal
1557:
1553:
1547:
1520:
1516:
1489:cite journal
1454:
1450:
1440:
1428:. Retrieved
1396:10665/325771
1386:
1377:
1357:
1350:
1330:
1323:
1311:. Retrieved
1276:. Retrieved
1271:
1239:. Retrieved
1234:
1231:"Vfend EPAR"
1225:
1213:. Retrieved
1206:
1197:
1185:. Retrieved
1180:
1171:
1157:
1140:
1128:
1120:Pharmacology
1114:prednisolone
1032:
1029:Interactions
1011:pancytopenia
1004:
1001:
958:
955:Side effects
950:
939:
936:
928:
925:
922:
899:
895:Scedosporium
893:
883:
880:Medical uses
871:
852:
837:
833:Scedosporium
831:
799:
796:Voriconazole
795:
794:
783:
433:
429:
425:
386:Elimination
377:
259:Legal status
253:Legal status
174:Voriconazole
155:License data
23:Voriconazole
18:
2690:Pyrimidines
2601:from market
2580:pentamidine
2541:lemon grass
2499:taurolidine
2469:polynoxylin
2370:flucytosine
2314:caspofungin
2238:terbinafine
2224:Allylamines
2086:fluconazole
2078:terconazole
2073:fluconazole
2044:tioconazole
2039:sulconazole
2029:oxiconazole
2024:omoconazole
1999:isoconazole
1974:croconazole
1932:inhibitors)
1930:demethylase
1887:Antifungals
1806:. Drugs.com
1575:2066/185528
1154:Brand names
1074:ciclosporin
1066:fluconazole
997:periostitis
967:reactions;
890:candidiasis
846:or used by
816:candidiasis
710: g·mol
650:100.157.870
580:CHEBI:10023
455:137234-62-9
408:Identifiers
372:Metabolites
218:Intravenous
141:MedlinePlus
113:Trade names
2654:Categories
2570:atovaquone
2551:orange oil
2514:tolnaftate
2509:tolciclate
2494:sulbentine
2464:haloprogin
2444:ciclopirox
2409:tavaborole
2401:inhibitors
2387:Systemic:
2368:Systemic:
2329:rezafungin
2324:micafungin
2319:cilofungin
2303:Systemic:
2297:inhibitors
2280:amorolfine
2259:butenafine
2216:inhibitors
2200:Systemic:
2177:ergosterol
2084:Systemic:
2014:miconazole
1964:climbazole
1949:bifonazole
1940:Imidazoles
1916:inhibitors
1913:Ergosterol
1618:6 November
1313:8 December
1278:15 October
1163:References
1094:ranitidine
1090:cimetidine
1082:omeprazole
1078:tacrolimus
1046:rifampicin
1019:leukopenia
715:3D model (
703:Molar mass
540:JFU09I87TR
511:ChemSpider
446:CAS Number
417:IUPAC name
348:Metabolism
332:96% (oral)
2611:Phase III
2599:Withdrawn
2556:patchouli
2504:ticlatone
2407:Topical:
2278:Topical:
2257:Topical:
2233:naftifine
2231:Topical:
2204:, hamycin
2192:natamycin
2185:Topical:
2158:abafungin
2156:Topical:
2149:Thiazoles
2132:Unknown:
2066:Topical:
2059:Triazoles
1984:econazole
1947:Topical:
1241:14 August
1102:macrolide
1098:indinavir
1086:phenytoin
1058:quinidine
1050:rifabutin
1042:sirolimus
942:galactose
859:pregnancy
600:ChEMBL638
399:Excretion
388:half-life
211:Routes of
185:Pregnancy
133:Monograph
127:Drugs.com
2644:Medicine
2454:dimazole
2197:nystatin
2179:binding)
1905:membrane
1849:31886997
1843:(NCBI).
1769:34631468
1718:36189133
1669:16569888
1584:12167683
1539:28636889
1481:27365388
1385:(2019).
1272:DailyMed
1187:30 March
1070:warfarin
977:pancreas
901:Fusarium
863:triazole
844:by mouth
839:Fusarium
786:(verify)
491:DrugBank
229:ATC code
222:by mouth
200: B3
187:category
169:DailyMed
2575:dapsone
2187:hamycin
1810:30 July
1760:8465512
1709:9508586
1660:1426935
1472:4967602
1430:30 July
1137:History
1110:digoxin
1035:hepatic
708:349.317
667:Formula
500:DB00582
466:PubChem
357:CYP2C19
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239: (
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1023:anemia
1021:, and
987:, and
975:, and
969:kidney
741:SMILES
591:ChEMBL
560:D00578
365:CYP3A4
361:CYP2C9
298:℞-only
296:
286:℞-only
272:
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1903:Wall/
1786:(PDF)
1062:ergot
973:liver
800:Vfend
761:InChI
717:JSmol
571:ChEBI
520:64684
480:71616
353:Liver
1893:and
1845:PMID
1812:2017
1765:PMID
1714:PMID
1665:PMID
1620:2016
1598:link
1580:PMID
1535:PMID
1495:link
1477:PMID
1432:2017
1363:ISBN
1336:ISBN
1315:2017
1280:2020
1243:2024
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1189:2024
1112:and
1060:and
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898:and
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1570:hdl
1562:doi
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470:CID
342:58%
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