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Chemical synthesis

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of a complex product, multiple procedures in sequence may be required to synthesize the product of interest, requiring a large amount of time. Skill in organic synthesis is prized among chemists and the synthesis of exceptionally valuable or difficult compounds has won chemists such as
301:. If a chemical synthesis starts from basic laboratory compounds, it is considered a purely synthetic process. If it starts from a product isolated from plants or animals and then proceeds to new compounds, the synthesis is described as a 313:
Inorganic synthesis and organometallic synthesis are applied to the preparation of compounds with significant non-organic content. An illustrative example is the preparation of the anti-cancer drug
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Alderden, Rebecca A.; Hall, Matthew D.; Hambley, Trevor W. (1 May 2006). "The Discovery and Development of Cisplatin".
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can be applied to formulate a desired product. This requires mixing the compounds in a reaction vessel, such as a
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Many strategies exist in chemical synthesis that are more complicated than simply converting a
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is an unwanted chemical reaction occurring which reduces the desired yield. The word
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Vogel, A.I.; Tatchell, A.R.; Furnis, B.S.; Hannaford, A.J.; Smith, P.W.G. (1996).
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and chemical manipulations usually involving one or more reactions. In modern
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as many as 11 different reactants form a single reaction product and for a "
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is a special type of chemical synthesis dealing with the synthesis of
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Planned series of chemical reactions to produce desired product(s)
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Advanced Organic Chemistry Part B: Reactions and Synthesis
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The amount produced by chemical synthesis is known as the
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from the original on Jun 30, 2023 – via Zenodo.
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Erlenmeyer–Plöchl azlactone and amino-acid synthesis
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was used first in a chemical context by the chemist
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For 4091: 4077: 4069: 3871: 3857: 3849: 3446: 1720: 1021: 562: 548: 540: 162:A chemical synthesis involves one or more 3376:Petrenko-Kritschenko piperidone synthesis 2831:Fritsch–Buttenberg–Wiechell rearrangement 120:Learn how and when to remove this message 3539:Intramolecular Diels–Alder cycloaddition 243:A to a reaction product B directly. For 403: 401: 397: 205:. Typically, yields are expressed as a 3559:Metal-centered cycloaddition reactions 3211:Debus–Radziszewski imidazole synthesis 1155:Bodroux–Chichibabin aldehyde synthesis 3705:Diazoalkane 1,3-dipolar cycloaddition 3609:Vinylcyclopropane (5+2) cycloaddition 3514:Diazoalkane 1,3-dipolar cycloaddition 3286:Hurd–Mori 1,2,3-thiadiazole synthesis 2781:Dowd–Beckwith ring-expansion reaction 1948:Hurd–Mori 1,2,3-thiadiazole synthesis 861:LFER solvent coefficients (data page) 7: 5006: 4039: 2516:Sharpless asymmetric dihydroxylation 1753:Methoxymethylenetriphenylphosphorane 58:adding citations to reliable sources 5030: 2641:Allen–Millar–Trippett rearrangement 3780:Nitrone-olefin (3+2) cycloaddition 3775:Niementowski quinazoline synthesis 3564:Nitrone-olefin (3+2) cycloaddition 3489:Azide-alkyne Huisgen cycloaddition 3351:Niementowski quinazoline synthesis 3106:Azide-alkyne Huisgen cycloaddition 2411:Meerwein–Ponndorf–Verley reduction 1963:Leimgruber–Batcho indole synthesis 25: 3604:Trimethylenemethane cycloaddition 3306:Johnson–Corey–Chaykovsky reaction 3171:Cadogan–Sundberg indole synthesis 3151:Bohlmann–Rahtz pyridine synthesis 3111:Baeyer–Emmerling indole synthesis 1918:Cadogan–Sundberg indole synthesis 1410:Johnson–Corey–Chaykovsky reaction 139:) is the artificial execution of 5029: 5017: 5005: 4994: 4993: 4050: 4038: 4027: 4026: 3700:Cook–Heilbron thiazole synthesis 3529:Hexadehydro Diels–Alder reaction 3356:Niementowski quinoline synthesis 3186:Cook–Heilbron thiazole synthesis 3131:Bischler–Möhlau indole synthesis 3041:Tiffeneau–Demjanov rearrangement 2671:Baker–Venkataraman rearrangement 1829:Horner–Wadsworth–Emmons reaction 1500:Mizoroki-Heck vs. Reductive Heck 1385:Horner–Wadsworth–Emmons reaction 896:Neighbouring group participation 439:Annalen der Chemie und Pharmacie 34: 3236:Fiesselmann thiophene synthesis 3066:Westphalen–LettrĂ© rearrangement 3046:Vinylcyclopropane rearrangement 2876:Kornblum–DeLaMare rearrangement 2521:Epoxidation of allylic alcohols 2431:Noyori asymmetric hydrogenation 2366:Kornblum–DeLaMare rearrangement 2041:Gallagher–Hollander degradation 412:(5th ed.). Prentice Hall. 45:needs additional citations for 3695:Chichibabin pyridine synthesis 3181:Chichibabin pyridine synthesis 3141:Blum–Ittah aziridine synthesis 2976:Ring expansion and contraction 1245:Cross dehydrogenative coupling 319:potassium tetrachloroplatinate 196:to isolate the final product. 1: 4358:Interface and colloid science 4112:Glossary of chemical formulae 3665:Bischler–Napieralski reaction 3623:Heterocycle forming reactions 3276:Hemetsberger indole synthesis 3136:Bischler–Napieralski reaction 3051:Wagner–Meerwein rearrangement 3021:Sommelet–Hauser rearrangement 3001:Seyferth–Gilbert homologation 2866:Ireland–Claisen rearrangement 2861:Hofmann–Martius rearrangement 2621:2,3-sigmatropic rearrangement 2236:Corey–Winter olefin synthesis 2161:Barton–McCombie deoxygenation 1804:Corey–Winter olefin synthesis 1758:Seyferth–Gilbert homologation 1625:Seyferth–Gilbert homologation 530:The Organic Synthesis Archive 3770:Lehmstedt–Tanasescu reaction 3730:Gabriel–Colman rearrangement 3685:Bucherer carbazole synthesis 3680:Borsche–Drechsel cyclization 3660:Bernthsen acridine synthesis 3645:Bamberger triazine synthesis 3630:Algar–Flynn–Oyamada reaction 3341:Nazarov cyclization reaction 3206:De Kimpe aziridine synthesis 3161:Bucherer carbazole synthesis 3156:Borsche–Drechsel cyclization 2926:Nazarov cyclization reaction 2906:Meyer–Schuster rearrangement 2836:Gabriel–Colman rearrangement 2586:Wolffenstein–Böters reaction 2471:Reduction of nitro compounds 2321:Grundmann aldehyde synthesis 2126:Algar–Flynn–Oyamada reaction 1535:Olefin conversion technology 1530:Nozaki–Hiyama–Kishi reaction 1325:Gabriel–Colman rearrangement 1215:Claisen-Schmidt condensation 1160:Bouveault aldehyde synthesis 365:Methods in Organic Synthesis 4635:Bioorganometallic chemistry 4122:List of inorganic compounds 4014:Volume combustion synthesis 3745:Hantzsch pyridine synthesis 3524:Enone–alkene cycloadditions 3346:Nenitzescu indole synthesis 3266:Hantzsch pyridine synthesis 3231:Ferrario–Ackermann reaction 2881:Kowalski ester homologation 2846:Halogen dance rearrangement 2691:Benzilic acid rearrangement 2116:Akabori amino-acid reaction 2076:Von Braun amide degradation 2021:Barbier–Wieland degradation 1973:Nenitzescu indole synthesis 1953:Kharasch–Sosnovsky reaction 1844:Julia–Kocienski olefination 1748:Kowalski ester homologation 1445:Kowalski ester homologation 1420:Julia–Kocienski olefination 1175:Cadiot–Chodkiewicz coupling 1100:Aza-Baylis–Hillman reaction 1045:Acetoacetic ester synthesis 756:Dynamic binding (chemistry) 746:Conrotatory and disrotatory 721:Charge remote fragmentation 5079: 4561:Dynamic covalent chemistry 4532:Enantioselective synthesis 4512:Physical organic chemistry 4465:Organolanthanide chemistry 3944:Enantioselective synthesis 3810:Robinson–Gabriel synthesis 3760:Kröhnke pyridine synthesis 3594:Retro-Diels–Alder reaction 3534:Imine Diels–Alder reaction 3321:Kröhnke pyridine synthesis 2936:Newman–Kwart rearrangement 2911:Mislow–Evans rearrangement 2821:Fischer–Hepp rearrangement 2766:Di-Ď€-methane rearrangement 2546:Stephen aldehyde synthesis 2281:Eschweiler–Clarke reaction 1998:Williamson ether synthesis 1315:Fujiwara–Moritani reaction 1220:Combes quinoline synthesis 1185:Carbonyl olefin metathesis 886:More O'Ferrall–Jencks plot 811:Grunwald–Winstein equation 781:Electron-withdrawing group 716:Catalytic resonance theory 270: 4989: 4150:Electroanalytical methods 4107: 4022: 3949:Fully automated synthesis 3894:Artificial gene synthesis 3820:Urech hydantoin synthesis 3800:Pomeranz–Fritsch reaction 3725:Fischer oxazole synthesis 3459:1,3-Dipolar cycloaddition 3431:Urech hydantoin synthesis 3401:Reissert indole synthesis 3386:Pomeranz–Fritsch reaction 3316:Knorr quinoline synthesis 3246:Fischer oxazole synthesis 3176:Camps quinoline synthesis 3096:1,3-Dipolar cycloaddition 2996:Semipinacol rearrangement 2971:Ramberg–Bäcklund reaction 2956:Piancatelli rearrangement 2896:McFadyen–Stevens reaction 2651:Alpha-ketol rearrangement 2406:McFadyen–Stevens reaction 2351:Kiliani–Fischer synthesis 2271:Elbs persulfate oxidation 2196:Bouveault–Blanc reduction 2156:Baeyer–Villiger oxidation 1988:Schotten–Baumann reaction 1864:Ramberg–Bäcklund reaction 1743:Kiliani–Fischer synthesis 1585:Ramberg–Bäcklund reaction 1570:Pinacol coupling reaction 1565:Piancatelli rearrangement 1460:Liebeskind–Srogl coupling 1310:Fujimoto–Belleau reaction 1027:List of organic reactions 891:Negative hyperconjugation 636: 578: 535:Natural product syntheses 299:Nobel Prize for Chemistry 257:multi-component reactions 143:to obtain one or several 4905:Nobel Prize in Chemistry 4821:Supramolecular chemistry 4460:Organometallic chemistry 3924:Custom peptide synthesis 3795:Pictet–Spengler reaction 3710:Einhorn–Brunner reaction 3675:Boger pyridine synthesis 3569:Oxo-Diels–Alder reaction 3484:Aza-Diels–Alder reaction 3381:Pictet–Spengler reaction 3281:Hofmann–Löffler reaction 3271:Hegedus indole synthesis 3241:Fischer indole synthesis 3116:Bartoli indole synthesis 3071:Willgerodt rearrangement 2901:McLafferty rearrangement 2811:Ferrier carbocyclization 2626:2,3-Wittig rearrangement 2616:1,2-Wittig rearrangement 2456:Parikh–Doering oxidation 2446:Oxygen rebound mechanism 2111:Adkins–Peterson reaction 2003:Yamaguchi esterification 1943:Hegedus indole synthesis 1908:Bartoli indole synthesis 1779:Bamford–Stevens reaction 1695:Weinreb ketone synthesis 1655:Stork enamine alkylation 1430:Knoevenagel condensation 1300:Ferrier carbocyclization 1190:Castro–Stephens coupling 816:Hammett acidity function 806:Free-energy relationship 751:Curtin–Hammett principle 736:Conformational isomerism 451:10.1002/jlac.18450540202 4843:Combinatorial chemistry 4754:Food physical chemistry 4717:Environmental chemistry 4601:Bioorthogonal chemistry 4527:Retrosynthetic analysis 4348:Chemical thermodynamics 4331:Spectroelectrochemistry 4274:Computational chemistry 3755:Knorr pyrrole synthesis 3690:Bucherer–Bergs reaction 3635:Allan–Robinson reaction 3614:Wagner-Jauregg reaction 3406:Ring-closing metathesis 3331:Larock indole synthesis 3311:Knorr pyrrole synthesis 3166:Bucherer–Bergs reaction 3031:Stieglitz rearrangement 3011:Skattebøl rearrangement 2981:Ring-closing metathesis 2841:Group transfer reaction 2806:Favorskii rearrangement 2746:Cornforth rearrangement 2676:Bamberger rearrangement 2581:Wolff–Kishner reduction 2401:Markó–Lam deoxygenation 2296:Fleming–Tamao oxidation 2291:Fischer–Tropsch process 1978:Oxymercuration reaction 1958:Knorr pyrrole synthesis 1784:Barton–Kellogg reaction 1690:Wagner-Jauregg reaction 1610:Ring-closing metathesis 1600:Reimer–Tiemann reaction 1590:Rauhut–Currier reaction 1505:Nef isocyanide reaction 1465:Malonic ester synthesis 1435:Knorr pyrrole synthesis 1370:High dilution principle 1305:Friedel–Crafts reaction 1240:Cross-coupling reaction 1165:Bucherer–Bergs reaction 1150:Blanc chloromethylation 1140:Blaise ketone synthesis 1115:Baylis–Hillman reaction 1110:Barton–Kellogg reaction 1085:Allan–Robinson reaction 991:Woodward–Hoffmann rules 726:Charge-transfer complex 4915:of element discoveries 4761:Agricultural chemistry 4749:Carbohydrate chemistry 4640:Bioinorganic chemistry 4505:Alkane stereochemistry 4450:Coordination chemistry 4279:Mathematical chemistry 4145:Instrumental chemistry 4004:Solvothermal synthesis 3954:Hydrothermal synthesis 3720:Feist–Benary synthesis 3494:Bradsher cycloaddition 3464:4+4 Photocycloaddition 3421:Simmons–Smith reaction 3366:Paternò–BĂĽchi reaction 3226:Feist–Benary synthesis 3216:Dieckmann condensation 2966:Pummerer rearrangement 2946:Oxy-Cope rearrangement 2921:Myers allene synthesis 2871:Jacobsen rearrangement 2786:Electrocyclic reaction 2761:Demjanov rearrangement 2716:Buchner ring expansion 2686:Beckmann rearrangement 2666:Aza-Cope rearrangement 2661:Arndt–Eistert reaction 2636:Alkyne zipper reaction 2556:Transfer hydrogenation 2531:Sharpless oxyamination 2506:Selenoxide elimination 2391:Lombardo methylenation 2316:Griesbaum coozonolysis 2226:Corey–Itsuno reduction 2201:Boyland–Sims oxidation 2141:Angeli–Rimini reaction 1789:Boord olefin synthesis 1733:Arndt–Eistert reaction 1725:Homologation reactions 1525:Nitro-Mannich reaction 1440:Kolbe–Schmitt reaction 1250:Cross-coupling partner 1170:Buchner ring expansion 1090:Arndt–Eistert reaction 856:Kinetic isotope effect 603:Rearrangement reaction 328: 194:purification procedure 178:Various reaction types 4910:Timeline of chemistry 4807:Post-mortem chemistry 4792:Clandestine chemistry 4722:Atmospheric chemistry 4645:Biophysical chemistry 4477:Solid-state chemistry 4427:Equilibrium chemistry 4336:Photoelectrochemistry 3999:Solid-phase synthesis 3579:Pauson–Khand reaction 3416:Sharpless epoxidation 3371:Pechmann condensation 3251:Friedländer synthesis 3201:Davis–Beirut reaction 3056:Wallach rearrangement 3026:Stevens rearrangement 2961:Pinacol rearrangement 2941:Overman rearrangement 2856:Hofmann rearrangement 2851:Hayashi rearrangement 2816:Ferrier rearrangement 2771:Dimroth rearrangement 2756:Curtius rearrangement 2751:Criegee rearrangement 2731:Claisen rearrangement 2721:Carroll rearrangement 2656:Amadori rearrangement 2646:Allylic rearrangement 2526:Sharpless epoxidation 2261:Dess–Martin oxidation 2186:Bohn–Schmidt reaction 2046:Hofmann rearrangement 1849:Kauffmann olefination 1772:Olefination reactions 1710:Wurtz–Fittig reaction 1545:Palladium–NHC complex 1425:Kauffmann olefination 1380:Homologation reaction 1230:Corey–House synthesis 1210:Claisen rearrangement 1006:Yukawa–Tsuno equation 966:Swain–Lupton equation 946:Spherical aromaticity 881:Möbius–HĂĽckel concept 666:Aromatic ring current 628:Substitution reaction 327: 295:Robert Burns Woodward 155:uses, the process is 4900:History of chemistry 4855:Chemical engineering 4630:Bioorganic chemistry 4380:Structural chemistry 4117:List of biomolecules 3919:Convergent synthesis 3899:Biomimetic synthesis 3785:Paal–Knorr synthesis 3655:Barton–Zard reaction 3599:Staudinger synthesis 3549:Ketene cycloaddition 3519:Diels–Alder reaction 3499:Cheletropic reaction 3479:Alkyne trimerisation 3361:Paal–Knorr synthesis 3326:Kulinkovich reaction 3301:Jacobsen epoxidation 3221:Diels–Alder reaction 3016:Smiles rearrangement 3006:Sigmatropic reaction 2891:Lossen rearrangement 2741:Corey–Fuchs reaction 2706:Boekelheide reaction 2701:Bergmann degradation 2631:Achmatowicz reaction 2416:Methionine sulfoxide 2216:Clemmensen reduction 2176:Bergmann degradation 2106:Acyloin condensation 2071:Strecker degradation 2026:Bergmann degradation 1993:Ullmann condensation 1859:Peterson olefination 1834:Hydrazone iodination 1814:Elimination reaction 1715:Zincke–Suhl reaction 1635:Sonogashira coupling 1595:Reformatsky reaction 1555:Peterson olefination 1520:Nierenstein reaction 1450:Kulinkovich reaction 1265:Diels–Alder reaction 1225:Corey–Fuchs reaction 1205:Claisen condensation 1075:Alkyne trimerisation 1050:Acyloin condensation 1016:ÎŁ-bishomoaromaticity 976:Thorpe–Ingold effect 588:Elimination reaction 349:Chemical engineering 261:telescopic synthesis 137:chemical combination 69:"Chemical synthesis" 54:improve this article 4923:The central science 4877:Ceramic engineering 4802:Forensic toxicology 4775:Chemistry education 4673:Radiation chemistry 4655:Interdisciplinarity 4608:Medicinal chemistry 4546:Fullerene chemistry 4422:Microwave chemistry 4291:Molecular mechanics 4286:Molecular modelling 3934:Divergent synthesis 3805:Prilezhaev reaction 3790:Pellizzari reaction 3469:(4+3) cycloaddition 3436:Van Leusen reaction 3411:Robinson annulation 3396:Pschorr cyclization 3391:Prilezhaev reaction 3121:Bergman cyclization 3076:Wolff rearrangement 3061:Weerman degradation 2951:Pericyclic reaction 2931:Neber rearrangement 2826:Fries rearrangement 2711:Brook rearrangement 2696:Bergman cyclization 2541:Staudinger reaction 2486:Rosenmund reduction 2476:Reductive amination 2441:Oppenauer oxidation 2231:Corey–Kim oxidation 2206:Cannizzaro reaction 2081:Weerman degradation 2056:Isosaccharinic acid 1968:Mukaiyama hydration 1824:Hofmann elimination 1809:Dehydrohalogenation 1794:Chugaev elimination 1615:Robinson annulation 1560:Pfitzinger reaction 1330:Gattermann reaction 1275:Wulff–Dötz reaction 1255:Dakin–West reaction 1180:Carbonyl allylation 1125:Bergman cyclization 911:Kennedy J. P. Orton 831:Hammond's postulate 801:Flippin–Lodge angle 771:Electromeric effect 696:Beta-silicon effect 681:Baker–Nathan effect 506:2006JChEd..83..728A 386:Automated synthesis 309:Inorganic synthesis 245:multistep synthesis 18:Multistep synthesis 5058:Chemical synthesis 4966:Chemical substance 4828:Chemical synthesis 4797:Forensic chemistry 4678:Actinide chemistry 4620:Clinical chemistry 4301:Molecular geometry 4296:Molecular dynamics 4251:Elemental analysis 4204:Separation process 3880:Chemical synthesis 3554:McCormack reaction 3504:Conia-ene reaction 3336:Madelung synthesis 3126:Biginelli reaction 2916:Mumm rearrangement 2801:Favorskii reaction 2736:Cope rearrangement 2726:Chan rearrangement 2491:Rubottom oxidation 2421:Miyaura borylation 2386:Lipid peroxidation 2381:Lindgren oxidation 2361:Kornblum oxidation 2356:Kolbe electrolysis 2301:Fukuyama reduction 2211:Carbonyl reduction 2061:Marker degradation 1923:Diazonium compound 1913:Boudouard reaction 1892:Carbon-heteroatom 1819:Grieco elimination 1605:Rieche formylation 1550:Passerini reaction 1480:Meerwein arylation 1400:Hydroxymethylation 1295:Favorskii reaction 1195:Chan rearrangement 1130:Biginelli reaction 1055:Aldol condensation 901:2-Norbornyl cation 876:Möbius aromaticity 871:Markovnikov's rule 766:Effective molarity 711:BĂĽrgi–Dunitz angle 701:Bicycloaromaticity 433:Kolbe, H. (1845). 339:Beilstein database 329: 186:round-bottom flask 141:chemical reactions 133:Chemical synthesis 5045: 5044: 4981:Quantum mechanics 4946:Chemical compound 4929:Chemical reaction 4867:Materials science 4785:General chemistry 4780:Amateur chemistry 4708:Photogeochemistry 4693:Stellar chemistry 4663:Nuclear chemistry 4584:Molecular biology 4551:Polymer chemistry 4522:Organic synthesis 4517:Organic reactions 4482:Ceramic chemistry 4472:Cluster chemistry 4402:Chemical kinetics 4390:Molecular physics 4269:Quantum chemistry 4182:Mass spectrometry 4066: 4065: 3979:Peptide synthesis 3974:Organic synthesis 3969:One-pot synthesis 3904:Bioretrosynthesis 3846: 3845: 3842: 3841: 3838: 3837: 3830:Wohl–Aue reaction 3474:6+4 Cycloaddition 3291:Iodolactonization 2611:1,2-rearrangement 2576:Wohl–Aue reaction 2496:Sabatier reaction 2461:Pinnick oxidation 2426:Mozingo reduction 2371:Leuckart reaction 2326:Haloform reaction 2241:Criegee oxidation 2221:Collins oxidation 2171:Benkeser reaction 2166:Bechamp reduction 2136:Andrussow process 2121:Alcohol oxidation 2031:Edman degradation 1938:Haloform reaction 1887: 1886: 1874:Takai olefination 1839:Julia olefination 1665:Takai olefination 1540:Olefin metathesis 1415:Julia olefination 1340:Grignard reaction 1320:Fukuyama coupling 1235:Coupling reaction 1200:Chan–Lam coupling 1070:Alkyne metathesis 1065:Alkane metathesis 921:Phosphaethynolate 826:George S. Hammond 786:Electronic effect 741:Conjugated system 623:Stereospecificity 618:Stereoselectivity 583:Addition reaction 572:organic reactions 514:10.1021/ed083p728 376:Peptide synthesis 371:Organic synthesis 286:organic compounds 282:Organic synthesis 273:Organic synthesis 267:Organic synthesis 253:cascade reactions 147:. This occurs by 130: 129: 122: 104: 16:(Redirected from 5070: 5033: 5032: 5021: 5009: 5008: 4997: 4996: 4941:Chemical element 4596:Chemical biology 4455:Magnetochemistry 4432:Mechanochemistry 4385:Chemical physics 4326:Electrochemistry 4231:Characterization 4093: 4086: 4079: 4070: 4054: 4042: 4041: 4030: 4029: 3964:Mechanosynthesis 3939:Electrosynthesis 3873: 3866: 3859: 3850: 3825:Wenker synthesis 3815:StollĂ© synthesis 3670:Bobbitt reaction 3640:Auwers synthesis 3584:Povarov reaction 3509:Cyclopropanation 3447: 3441:Wenker synthesis 3196:Darzens reaction 3146:Bobbitt reaction 2991:Schmidt reaction 2796:Enyne metathesis 2571:Whiting reaction 2566:Wharton reaction 2511:Shapiro reaction 2501:Sarett oxidation 2466:PrĂ©vost reaction 2276:Emde degradation 2086:Wohl degradation 2066:Ruff degradation 2036:Emde degradation 1933:Grignard reagent 1869:Shapiro reaction 1854:McMurry reaction 1721: 1685:Ullmann reaction 1650:StollĂ© synthesis 1640:Stetter reaction 1630:Shapiro reaction 1620:Sakurai reaction 1515:Negishi coupling 1495:Minisci reaction 1490:Michael reaction 1475:McMurry reaction 1470:Mannich reaction 1350:Hammick reaction 1345:Grignard reagent 1285:Enyne metathesis 1270:Doebner reaction 1260:Darzens reaction 1105:Barbier reaction 1095:Auwers synthesis 1022: 996:Woodward's rules 961:Superaromaticity 951:Spiroaromaticity 851:Inductive effect 846:Hyperconjugation 821:Hammett equation 761:Edwards equation 613:Regioselectivity 564: 557: 550: 541: 518: 517: 488: 482: 481: 473: 467: 466: 430: 424: 423: 405: 359:Electrosynthesis 215:limiting reagent 182:chemical reactor 125: 118: 114: 111: 105: 103: 62: 38: 30: 21: 5078: 5077: 5073: 5072: 5071: 5069: 5068: 5067: 5048: 5047: 5046: 5041: 4985: 4888: 4882:Polymer science 4838:Click chemistry 4833:Green chemistry 4727:Ocean chemistry 4703:Biogeochemistry 4649: 4565: 4537:Total synthesis 4500:Stereochemistry 4486: 4436: 4353:Surface science 4343:Thermochemistry 4312: 4255: 4226:Crystallography 4131: 4103: 4097: 4067: 4062: 4018: 4009:Total synthesis 3882: 3877: 3847: 3834: 3735:Gewald reaction 3618: 3445: 3426:Skraup reaction 3261:Graham reaction 3256:Gewald reaction 3087: 3080: 2602: 2595: 2551:Swern oxidation 2536:Stahl oxidation 2481:Riley oxidation 2436:Omega oxidation 2396:Luche reduction 2346:Jones oxidation 2311:Glycol cleavage 2306:Ganem oxidation 2251:Davis oxidation 2246:Dakin oxidation 2181:Birch reduction 2131:Amide reduction 2097: 2090: 2051:Hooker reaction 2013: 2007: 1895: 1893: 1883: 1879:Wittig reaction 1767: 1763:Wittig reaction 1738:Hooker reaction 1719: 1700:Wittig reaction 1675:Thorpe reaction 1660:Suzuki reaction 1645:Stille reaction 1580:Quelet reaction 1455:Kumada coupling 1405:Ivanov reaction 1395:Hydrovinylation 1375:Hiyama coupling 1335:Glaser coupling 1145:Blaise reaction 1135:Bingel reaction 1120:Benary reaction 1037: 1035: 1029: 1020: 916:Passive binding 836:Homoaromaticity 686:Baldwin's rules 661:Antiaromaticity 656:Anomeric effect 632: 574: 568: 526: 521: 490: 489: 485: 475: 474: 470: 432: 431: 427: 420: 407: 406: 399: 395: 390: 381:Total synthesis 354:Click chemistry 334: 311: 290:total synthesis 279: 271:Main articles: 269: 237: 126: 115: 109: 106: 63: 61: 51: 39: 28: 23: 22: 15: 12: 11: 5: 5076: 5074: 5066: 5065: 5060: 5050: 5049: 5043: 5042: 5040: 5039: 5027: 5015: 5003: 4990: 4987: 4986: 4984: 4983: 4978: 4973: 4968: 4963: 4958: 4953: 4948: 4943: 4938: 4937: 4936: 4926: 4919: 4918: 4917: 4907: 4902: 4896: 4894: 4890: 4889: 4887: 4886: 4885: 4884: 4879: 4874: 4864: 4863: 4862: 4852: 4851: 4850: 4845: 4840: 4835: 4825: 4824: 4823: 4812: 4811: 4810: 4809: 4804: 4794: 4789: 4788: 4787: 4782: 4771: 4770: 4769: 4768: 4766:Soil chemistry 4758: 4757: 4756: 4751: 4744:Food chemistry 4741: 4739:Carbochemistry 4736: 4734:Clay chemistry 4731: 4730: 4729: 4724: 4713: 4712: 4711: 4710: 4705: 4695: 4689:Astrochemistry 4685:Cosmochemistry 4682: 4681: 4680: 4675: 4670: 4668:Radiochemistry 4659: 4657: 4651: 4650: 4648: 4647: 4642: 4637: 4632: 4627: 4625:Neurochemistry 4622: 4617: 4616: 4615: 4605: 4604: 4603: 4593: 4592: 4591: 4586: 4575: 4573: 4567: 4566: 4564: 4563: 4558: 4556:Petrochemistry 4553: 4548: 4543: 4534: 4529: 4524: 4519: 4514: 4509: 4508: 4507: 4496: 4494: 4488: 4487: 4485: 4484: 4479: 4474: 4469: 4468: 4467: 4457: 4452: 4446: 4444: 4438: 4437: 4435: 4434: 4429: 4424: 4419: 4417:Spin chemistry 4414: 4412:Photochemistry 4409: 4404: 4399: 4397:Femtochemistry 4394: 4393: 4392: 4382: 4377: 4372: 4367: 4366: 4365: 4355: 4350: 4345: 4340: 4339: 4338: 4333: 4322: 4320: 4314: 4313: 4311: 4310: 4309: 4308: 4298: 4293: 4288: 4283: 4282: 4281: 4271: 4265: 4263: 4257: 4256: 4254: 4253: 4248: 4243: 4238: 4233: 4228: 4223: 4222: 4221: 4216: 4209:Chromatography 4206: 4201: 4200: 4199: 4194: 4189: 4179: 4178: 4177: 4172: 4167: 4162: 4152: 4147: 4141: 4139: 4133: 4132: 4130: 4129: 4127:Periodic table 4124: 4119: 4114: 4108: 4105: 4104: 4098: 4096: 4095: 4088: 4081: 4073: 4064: 4063: 4061: 4060: 4048: 4036: 4023: 4020: 4019: 4017: 4016: 4011: 4006: 4001: 3996: 3991: 3989:Retrosynthesis 3986: 3984:Radiosynthesis 3981: 3976: 3971: 3966: 3961: 3956: 3951: 3946: 3941: 3936: 3931: 3929:Direct process 3926: 3921: 3916: 3914:Chemosynthesis 3911: 3906: 3901: 3896: 3890: 3888: 3884: 3883: 3878: 3876: 3875: 3868: 3861: 3853: 3844: 3843: 3840: 3839: 3836: 3835: 3833: 3832: 3827: 3822: 3817: 3812: 3807: 3802: 3797: 3792: 3787: 3782: 3777: 3772: 3767: 3762: 3757: 3752: 3747: 3742: 3740:Hantzsch ester 3737: 3732: 3727: 3722: 3717: 3712: 3707: 3702: 3697: 3692: 3687: 3682: 3677: 3672: 3667: 3662: 3657: 3652: 3650:Banert cascade 3647: 3642: 3637: 3632: 3626: 3624: 3620: 3619: 3617: 3616: 3611: 3606: 3601: 3596: 3591: 3589:Prato reaction 3586: 3581: 3576: 3571: 3566: 3561: 3556: 3551: 3546: 3541: 3536: 3531: 3526: 3521: 3516: 3511: 3506: 3501: 3496: 3491: 3486: 3481: 3476: 3471: 3466: 3461: 3455: 3453: 3444: 3443: 3438: 3433: 3428: 3423: 3418: 3413: 3408: 3403: 3398: 3393: 3388: 3383: 3378: 3373: 3368: 3363: 3358: 3353: 3348: 3343: 3338: 3333: 3328: 3323: 3318: 3313: 3308: 3303: 3298: 3293: 3288: 3283: 3278: 3273: 3268: 3263: 3258: 3253: 3248: 3243: 3238: 3233: 3228: 3223: 3218: 3213: 3208: 3203: 3198: 3193: 3188: 3183: 3178: 3173: 3168: 3163: 3158: 3153: 3148: 3143: 3138: 3133: 3128: 3123: 3118: 3113: 3108: 3103: 3098: 3092: 3090: 3082: 3081: 3079: 3078: 3073: 3068: 3063: 3058: 3053: 3048: 3043: 3038: 3033: 3028: 3023: 3018: 3013: 3008: 3003: 2998: 2993: 2988: 2983: 2978: 2973: 2968: 2963: 2958: 2953: 2948: 2943: 2938: 2933: 2928: 2923: 2918: 2913: 2908: 2903: 2898: 2893: 2888: 2883: 2878: 2873: 2868: 2863: 2858: 2853: 2848: 2843: 2838: 2833: 2828: 2823: 2818: 2813: 2808: 2803: 2798: 2793: 2788: 2783: 2778: 2773: 2768: 2763: 2758: 2753: 2748: 2743: 2738: 2733: 2728: 2723: 2718: 2713: 2708: 2703: 2698: 2693: 2688: 2683: 2681:Banert cascade 2678: 2673: 2668: 2663: 2658: 2653: 2648: 2643: 2638: 2633: 2628: 2623: 2618: 2613: 2607: 2605: 2601:Rearrangement 2597: 2596: 2594: 2593: 2591:Zinin reaction 2588: 2583: 2578: 2573: 2568: 2563: 2561:Wacker process 2558: 2553: 2548: 2543: 2538: 2533: 2528: 2523: 2518: 2513: 2508: 2503: 2498: 2493: 2488: 2483: 2478: 2473: 2468: 2463: 2458: 2453: 2448: 2443: 2438: 2433: 2428: 2423: 2418: 2413: 2408: 2403: 2398: 2393: 2388: 2383: 2378: 2373: 2368: 2363: 2358: 2353: 2348: 2343: 2338: 2336:Hydrogenolysis 2333: 2328: 2323: 2318: 2313: 2308: 2303: 2298: 2293: 2288: 2286:Étard reaction 2283: 2278: 2273: 2268: 2263: 2258: 2253: 2248: 2243: 2238: 2233: 2228: 2223: 2218: 2213: 2208: 2203: 2198: 2193: 2191:Bosch reaction 2188: 2183: 2178: 2173: 2168: 2163: 2158: 2153: 2148: 2143: 2138: 2133: 2128: 2123: 2118: 2113: 2108: 2102: 2100: 2096:Organic redox 2092: 2091: 2089: 2088: 2083: 2078: 2073: 2068: 2063: 2058: 2053: 2048: 2043: 2038: 2033: 2028: 2023: 2017: 2015: 2009: 2008: 2006: 2005: 2000: 1995: 1990: 1985: 1980: 1975: 1970: 1965: 1960: 1955: 1950: 1945: 1940: 1935: 1930: 1928:Esterification 1925: 1920: 1915: 1910: 1905: 1899: 1897: 1889: 1888: 1885: 1884: 1882: 1881: 1876: 1871: 1866: 1861: 1856: 1851: 1846: 1841: 1836: 1831: 1826: 1821: 1816: 1811: 1806: 1801: 1796: 1791: 1786: 1781: 1775: 1773: 1769: 1768: 1766: 1765: 1760: 1755: 1750: 1745: 1740: 1735: 1729: 1727: 1718: 1717: 1712: 1707: 1705:Wurtz reaction 1702: 1697: 1692: 1687: 1682: 1677: 1672: 1667: 1662: 1657: 1652: 1647: 1642: 1637: 1632: 1627: 1622: 1617: 1612: 1607: 1602: 1597: 1592: 1587: 1582: 1577: 1575:Prins reaction 1572: 1567: 1562: 1557: 1552: 1547: 1542: 1537: 1532: 1527: 1522: 1517: 1512: 1507: 1502: 1497: 1492: 1487: 1482: 1477: 1472: 1467: 1462: 1457: 1452: 1447: 1442: 1437: 1432: 1427: 1422: 1417: 1412: 1407: 1402: 1397: 1392: 1390:Hydrocyanation 1387: 1382: 1377: 1372: 1367: 1362: 1360:Henry reaction 1357: 1352: 1347: 1342: 1337: 1332: 1327: 1322: 1317: 1312: 1307: 1302: 1297: 1292: 1287: 1282: 1277: 1272: 1267: 1262: 1257: 1252: 1247: 1242: 1237: 1232: 1227: 1222: 1217: 1212: 1207: 1202: 1197: 1192: 1187: 1182: 1177: 1172: 1167: 1162: 1157: 1152: 1147: 1142: 1137: 1132: 1127: 1122: 1117: 1112: 1107: 1102: 1097: 1092: 1087: 1082: 1077: 1072: 1067: 1062: 1060:Aldol reaction 1057: 1052: 1047: 1041: 1039: 1034:Carbon-carbon 1031: 1030: 1025: 1019: 1018: 1013: 1011:Zaitsev's rule 1008: 1003: 998: 993: 988: 983: 978: 973: 968: 963: 958: 956:Steric effects 953: 948: 943: 938: 933: 928: 923: 918: 913: 908: 903: 898: 893: 888: 883: 878: 873: 868: 863: 858: 853: 848: 843: 838: 833: 828: 823: 818: 813: 808: 803: 798: 793: 788: 783: 778: 773: 768: 763: 758: 753: 748: 743: 738: 733: 728: 723: 718: 713: 708: 703: 698: 693: 688: 683: 678: 673: 668: 663: 658: 653: 648: 643: 637: 634: 633: 631: 630: 625: 620: 615: 610: 608:Redox reaction 605: 600: 595: 593:Polymerization 590: 585: 579: 576: 575: 569: 567: 566: 559: 552: 544: 538: 537: 532: 525: 524:External links 522: 520: 519: 494:J. Chem. Educ. 483: 468: 445:(2): 145–188. 425: 418: 396: 394: 391: 389: 388: 383: 378: 373: 368: 361: 356: 351: 346: 341: 335: 333: 330: 310: 307: 268: 265: 236: 233: 202:reaction yield 159:and reliable. 128: 127: 42: 40: 33: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 5075: 5064: 5061: 5059: 5056: 5055: 5053: 5038: 5037: 5028: 5026: 5025: 5020: 5016: 5014: 5013: 5004: 5002: 5001: 4992: 4991: 4988: 4982: 4979: 4977: 4974: 4972: 4971:Chemical bond 4969: 4967: 4964: 4962: 4959: 4957: 4954: 4952: 4949: 4947: 4944: 4942: 4939: 4935: 4932: 4931: 4930: 4927: 4924: 4920: 4916: 4913: 4912: 4911: 4908: 4906: 4903: 4901: 4898: 4897: 4895: 4891: 4883: 4880: 4878: 4875: 4873: 4870: 4869: 4868: 4865: 4861: 4860:Stoichiometry 4858: 4857: 4856: 4853: 4849: 4846: 4844: 4841: 4839: 4836: 4834: 4831: 4830: 4829: 4826: 4822: 4819: 4818: 4817: 4816:Nanochemistry 4814: 4813: 4808: 4805: 4803: 4800: 4799: 4798: 4795: 4793: 4790: 4786: 4783: 4781: 4778: 4777: 4776: 4773: 4772: 4767: 4764: 4763: 4762: 4759: 4755: 4752: 4750: 4747: 4746: 4745: 4742: 4740: 4737: 4735: 4732: 4728: 4725: 4723: 4720: 4719: 4718: 4715: 4714: 4709: 4706: 4704: 4701: 4700: 4699: 4696: 4694: 4690: 4686: 4683: 4679: 4676: 4674: 4671: 4669: 4666: 4665: 4664: 4661: 4660: 4658: 4656: 4652: 4646: 4643: 4641: 4638: 4636: 4633: 4631: 4628: 4626: 4623: 4621: 4618: 4614: 4611: 4610: 4609: 4606: 4602: 4599: 4598: 4597: 4594: 4590: 4587: 4585: 4582: 4581: 4580: 4577: 4576: 4574: 4572: 4568: 4562: 4559: 4557: 4554: 4552: 4549: 4547: 4544: 4542: 4541:Semisynthesis 4538: 4535: 4533: 4530: 4528: 4525: 4523: 4520: 4518: 4515: 4513: 4510: 4506: 4503: 4502: 4501: 4498: 4497: 4495: 4493: 4489: 4483: 4480: 4478: 4475: 4473: 4470: 4466: 4463: 4462: 4461: 4458: 4456: 4453: 4451: 4448: 4447: 4445: 4443: 4439: 4433: 4430: 4428: 4425: 4423: 4420: 4418: 4415: 4413: 4410: 4408: 4405: 4403: 4400: 4398: 4395: 4391: 4388: 4387: 4386: 4383: 4381: 4378: 4376: 4375:Sonochemistry 4373: 4371: 4370:Cryochemistry 4368: 4364: 4363:Micromeritics 4361: 4360: 4359: 4356: 4354: 4351: 4349: 4346: 4344: 4341: 4337: 4334: 4332: 4329: 4328: 4327: 4324: 4323: 4321: 4319: 4315: 4307: 4304: 4303: 4302: 4299: 4297: 4294: 4292: 4289: 4287: 4284: 4280: 4277: 4276: 4275: 4272: 4270: 4267: 4266: 4264: 4262: 4258: 4252: 4249: 4247: 4244: 4242: 4241:Wet chemistry 4239: 4237: 4234: 4232: 4229: 4227: 4224: 4220: 4217: 4215: 4212: 4211: 4210: 4207: 4205: 4202: 4198: 4195: 4193: 4190: 4188: 4185: 4184: 4183: 4180: 4176: 4173: 4171: 4168: 4166: 4163: 4161: 4158: 4157: 4156: 4153: 4151: 4148: 4146: 4143: 4142: 4140: 4138: 4134: 4128: 4125: 4123: 4120: 4118: 4115: 4113: 4110: 4109: 4106: 4102: 4094: 4089: 4087: 4082: 4080: 4075: 4074: 4071: 4059: 4058: 4053: 4049: 4047: 4046: 4037: 4035: 4034: 4025: 4024: 4021: 4015: 4012: 4010: 4007: 4005: 4002: 4000: 3997: 3995: 3994:Semisynthesis 3992: 3990: 3987: 3985: 3982: 3980: 3977: 3975: 3972: 3970: 3967: 3965: 3962: 3960: 3957: 3955: 3952: 3950: 3947: 3945: 3942: 3940: 3937: 3935: 3932: 3930: 3927: 3925: 3922: 3920: 3917: 3915: 3912: 3910: 3907: 3905: 3902: 3900: 3897: 3895: 3892: 3891: 3889: 3885: 3881: 3874: 3869: 3867: 3862: 3860: 3855: 3854: 3851: 3831: 3828: 3826: 3823: 3821: 3818: 3816: 3813: 3811: 3808: 3806: 3803: 3801: 3798: 3796: 3793: 3791: 3788: 3786: 3783: 3781: 3778: 3776: 3773: 3771: 3768: 3766: 3763: 3761: 3758: 3756: 3753: 3751: 3750:Herz reaction 3748: 3746: 3743: 3741: 3738: 3736: 3733: 3731: 3728: 3726: 3723: 3721: 3718: 3716: 3713: 3711: 3708: 3706: 3703: 3701: 3698: 3696: 3693: 3691: 3688: 3686: 3683: 3681: 3678: 3676: 3673: 3671: 3668: 3666: 3663: 3661: 3658: 3656: 3653: 3651: 3648: 3646: 3643: 3641: 3638: 3636: 3633: 3631: 3628: 3627: 3625: 3621: 3615: 3612: 3610: 3607: 3605: 3602: 3600: 3597: 3595: 3592: 3590: 3587: 3585: 3582: 3580: 3577: 3575: 3572: 3570: 3567: 3565: 3562: 3560: 3557: 3555: 3552: 3550: 3547: 3545: 3542: 3540: 3537: 3535: 3532: 3530: 3527: 3525: 3522: 3520: 3517: 3515: 3512: 3510: 3507: 3505: 3502: 3500: 3497: 3495: 3492: 3490: 3487: 3485: 3482: 3480: 3477: 3475: 3472: 3470: 3467: 3465: 3462: 3460: 3457: 3456: 3454: 3452: 3451:Cycloaddition 3448: 3442: 3439: 3437: 3434: 3432: 3429: 3427: 3424: 3422: 3419: 3417: 3414: 3412: 3409: 3407: 3404: 3402: 3399: 3397: 3394: 3392: 3389: 3387: 3384: 3382: 3379: 3377: 3374: 3372: 3369: 3367: 3364: 3362: 3359: 3357: 3354: 3352: 3349: 3347: 3344: 3342: 3339: 3337: 3334: 3332: 3329: 3327: 3324: 3322: 3319: 3317: 3314: 3312: 3309: 3307: 3304: 3302: 3299: 3297: 3296:Isay reaction 3294: 3292: 3289: 3287: 3284: 3282: 3279: 3277: 3274: 3272: 3269: 3267: 3264: 3262: 3259: 3257: 3254: 3252: 3249: 3247: 3244: 3242: 3239: 3237: 3234: 3232: 3229: 3227: 3224: 3222: 3219: 3217: 3214: 3212: 3209: 3207: 3204: 3202: 3199: 3197: 3194: 3192: 3191:Cycloaddition 3189: 3187: 3184: 3182: 3179: 3177: 3174: 3172: 3169: 3167: 3164: 3162: 3159: 3157: 3154: 3152: 3149: 3147: 3144: 3142: 3139: 3137: 3134: 3132: 3129: 3127: 3124: 3122: 3119: 3117: 3114: 3112: 3109: 3107: 3104: 3102: 3099: 3097: 3094: 3093: 3091: 3089: 3086:Ring forming 3083: 3077: 3074: 3072: 3069: 3067: 3064: 3062: 3059: 3057: 3054: 3052: 3049: 3047: 3044: 3042: 3039: 3037: 3034: 3032: 3029: 3027: 3024: 3022: 3019: 3017: 3014: 3012: 3009: 3007: 3004: 3002: 2999: 2997: 2994: 2992: 2989: 2987: 2986:Rupe reaction 2984: 2982: 2979: 2977: 2974: 2972: 2969: 2967: 2964: 2962: 2959: 2957: 2954: 2952: 2949: 2947: 2944: 2942: 2939: 2937: 2934: 2932: 2929: 2927: 2924: 2922: 2919: 2917: 2914: 2912: 2909: 2907: 2904: 2902: 2899: 2897: 2894: 2892: 2889: 2887: 2884: 2882: 2879: 2877: 2874: 2872: 2869: 2867: 2864: 2862: 2859: 2857: 2854: 2852: 2849: 2847: 2844: 2842: 2839: 2837: 2834: 2832: 2829: 2827: 2824: 2822: 2819: 2817: 2814: 2812: 2809: 2807: 2804: 2802: 2799: 2797: 2794: 2792: 2789: 2787: 2784: 2782: 2779: 2777: 2774: 2772: 2769: 2767: 2764: 2762: 2759: 2757: 2754: 2752: 2749: 2747: 2744: 2742: 2739: 2737: 2734: 2732: 2729: 2727: 2724: 2722: 2719: 2717: 2714: 2712: 2709: 2707: 2704: 2702: 2699: 2697: 2694: 2692: 2689: 2687: 2684: 2682: 2679: 2677: 2674: 2672: 2669: 2667: 2664: 2662: 2659: 2657: 2654: 2652: 2649: 2647: 2644: 2642: 2639: 2637: 2634: 2632: 2629: 2627: 2624: 2622: 2619: 2617: 2614: 2612: 2609: 2608: 2606: 2604: 2598: 2592: 2589: 2587: 2584: 2582: 2579: 2577: 2574: 2572: 2569: 2567: 2564: 2562: 2559: 2557: 2554: 2552: 2549: 2547: 2544: 2542: 2539: 2537: 2534: 2532: 2529: 2527: 2524: 2522: 2519: 2517: 2514: 2512: 2509: 2507: 2504: 2502: 2499: 2497: 2494: 2492: 2489: 2487: 2484: 2482: 2479: 2477: 2474: 2472: 2469: 2467: 2464: 2462: 2459: 2457: 2454: 2452: 2449: 2447: 2444: 2442: 2439: 2437: 2434: 2432: 2429: 2427: 2424: 2422: 2419: 2417: 2414: 2412: 2409: 2407: 2404: 2402: 2399: 2397: 2394: 2392: 2389: 2387: 2384: 2382: 2379: 2377: 2376:Ley oxidation 2374: 2372: 2369: 2367: 2364: 2362: 2359: 2357: 2354: 2352: 2349: 2347: 2344: 2342: 2341:Hydroxylation 2339: 2337: 2334: 2332: 2331:Hydrogenation 2329: 2327: 2324: 2322: 2319: 2317: 2314: 2312: 2309: 2307: 2304: 2302: 2299: 2297: 2294: 2292: 2289: 2287: 2284: 2282: 2279: 2277: 2274: 2272: 2269: 2267: 2266:DNA oxidation 2264: 2262: 2259: 2257: 2256:Deoxygenation 2254: 2252: 2249: 2247: 2244: 2242: 2239: 2237: 2234: 2232: 2229: 2227: 2224: 2222: 2219: 2217: 2214: 2212: 2209: 2207: 2204: 2202: 2199: 2197: 2194: 2192: 2189: 2187: 2184: 2182: 2179: 2177: 2174: 2172: 2169: 2167: 2164: 2162: 2159: 2157: 2154: 2152: 2149: 2147: 2146:Aromatization 2144: 2142: 2139: 2137: 2134: 2132: 2129: 2127: 2124: 2122: 2119: 2117: 2114: 2112: 2109: 2107: 2104: 2103: 2101: 2099: 2093: 2087: 2084: 2082: 2079: 2077: 2074: 2072: 2069: 2067: 2064: 2062: 2059: 2057: 2054: 2052: 2049: 2047: 2044: 2042: 2039: 2037: 2034: 2032: 2029: 2027: 2024: 2022: 2019: 2018: 2016: 2010: 2004: 2001: 1999: 1996: 1994: 1991: 1989: 1986: 1984: 1983:Reed reaction 1981: 1979: 1976: 1974: 1971: 1969: 1966: 1964: 1961: 1959: 1956: 1954: 1951: 1949: 1946: 1944: 1941: 1939: 1936: 1934: 1931: 1929: 1926: 1924: 1921: 1919: 1916: 1914: 1911: 1909: 1906: 1904: 1901: 1900: 1898: 1894:bond forming 1890: 1880: 1877: 1875: 1872: 1870: 1867: 1865: 1862: 1860: 1857: 1855: 1852: 1850: 1847: 1845: 1842: 1840: 1837: 1835: 1832: 1830: 1827: 1825: 1822: 1820: 1817: 1815: 1812: 1810: 1807: 1805: 1802: 1800: 1799:Cope reaction 1797: 1795: 1792: 1790: 1787: 1785: 1782: 1780: 1777: 1776: 1774: 1770: 1764: 1761: 1759: 1756: 1754: 1751: 1749: 1746: 1744: 1741: 1739: 1736: 1734: 1731: 1730: 1728: 1726: 1722: 1716: 1713: 1711: 1708: 1706: 1703: 1701: 1698: 1696: 1693: 1691: 1688: 1686: 1683: 1681: 1678: 1676: 1673: 1671: 1668: 1666: 1663: 1661: 1658: 1656: 1653: 1651: 1648: 1646: 1643: 1641: 1638: 1636: 1633: 1631: 1628: 1626: 1623: 1621: 1618: 1616: 1613: 1611: 1608: 1606: 1603: 1601: 1598: 1596: 1593: 1591: 1588: 1586: 1583: 1581: 1578: 1576: 1573: 1571: 1568: 1566: 1563: 1561: 1558: 1556: 1553: 1551: 1548: 1546: 1543: 1541: 1538: 1536: 1533: 1531: 1528: 1526: 1523: 1521: 1518: 1516: 1513: 1511: 1510:Nef synthesis 1508: 1506: 1503: 1501: 1498: 1496: 1493: 1491: 1488: 1486: 1485:Methylenation 1483: 1481: 1478: 1476: 1473: 1471: 1468: 1466: 1463: 1461: 1458: 1456: 1453: 1451: 1448: 1446: 1443: 1441: 1438: 1436: 1433: 1431: 1428: 1426: 1423: 1421: 1418: 1416: 1413: 1411: 1408: 1406: 1403: 1401: 1398: 1396: 1393: 1391: 1388: 1386: 1383: 1381: 1378: 1376: 1373: 1371: 1368: 1366: 1363: 1361: 1358: 1356: 1355:Heck reaction 1353: 1351: 1348: 1346: 1343: 1341: 1338: 1336: 1333: 1331: 1328: 1326: 1323: 1321: 1318: 1316: 1313: 1311: 1308: 1306: 1303: 1301: 1298: 1296: 1293: 1291: 1288: 1286: 1283: 1281: 1278: 1276: 1273: 1271: 1268: 1266: 1263: 1261: 1258: 1256: 1253: 1251: 1248: 1246: 1243: 1241: 1238: 1236: 1233: 1231: 1228: 1226: 1223: 1221: 1218: 1216: 1213: 1211: 1208: 1206: 1203: 1201: 1198: 1196: 1193: 1191: 1188: 1186: 1183: 1181: 1178: 1176: 1173: 1171: 1168: 1166: 1163: 1161: 1158: 1156: 1153: 1151: 1148: 1146: 1143: 1141: 1138: 1136: 1133: 1131: 1128: 1126: 1123: 1121: 1118: 1116: 1113: 1111: 1108: 1106: 1103: 1101: 1098: 1096: 1093: 1091: 1088: 1086: 1083: 1081: 1078: 1076: 1073: 1071: 1068: 1066: 1063: 1061: 1058: 1056: 1053: 1051: 1048: 1046: 1043: 1042: 1040: 1036:bond forming 1032: 1028: 1023: 1017: 1014: 1012: 1009: 1007: 1004: 1002: 1001:Y-aromaticity 999: 997: 994: 992: 989: 987: 986:Walsh diagram 984: 982: 979: 977: 974: 972: 971:Taft equation 969: 967: 964: 962: 959: 957: 954: 952: 949: 947: 944: 942: 941:ÎŁ-aromaticity 939: 937: 934: 932: 929: 927: 924: 922: 919: 917: 914: 912: 909: 907: 904: 902: 899: 897: 894: 892: 889: 887: 884: 882: 879: 877: 874: 872: 869: 867: 866:Marcus theory 864: 862: 859: 857: 854: 852: 849: 847: 844: 842: 841:HĂĽckel's rule 839: 837: 834: 832: 829: 827: 824: 822: 819: 817: 814: 812: 809: 807: 804: 802: 799: 797: 796:Evelyn effect 794: 792: 789: 787: 784: 782: 779: 777: 776:Electron-rich 774: 772: 769: 767: 764: 762: 759: 757: 754: 752: 749: 747: 744: 742: 739: 737: 734: 732: 729: 727: 724: 722: 719: 717: 714: 712: 709: 707: 704: 702: 699: 697: 694: 692: 691:Bema Hapothle 689: 687: 684: 682: 679: 677: 674: 672: 669: 667: 664: 662: 659: 657: 654: 652: 649: 647: 644: 642: 639: 638: 635: 629: 626: 624: 621: 619: 616: 614: 611: 609: 606: 604: 601: 599: 596: 594: 591: 589: 586: 584: 581: 580: 577: 573: 565: 560: 558: 553: 551: 546: 545: 542: 536: 533: 531: 528: 527: 523: 515: 511: 507: 503: 499: 496: 495: 487: 484: 479: 472: 469: 464: 460: 456: 452: 448: 444: 440: 436: 429: 426: 421: 419:0-582-46236-3 415: 411: 404: 402: 398: 392: 387: 384: 382: 379: 377: 374: 372: 369: 367: 366: 362: 360: 357: 355: 352: 350: 347: 345: 342: 340: 337: 336: 331: 326: 322: 320: 316: 308: 306: 304: 303:semisynthetic 300: 296: 291: 287: 283: 278: 274: 266: 264: 262: 258: 254: 250: 246: 242: 234: 232: 230: 229:Hermann Kolbe 226: 222: 221: 220:side reaction 216: 212: 208: 204: 203: 197: 195: 191: 187: 183: 179: 175: 171: 170: 165: 160: 158: 154: 150: 146: 142: 138: 134: 124: 121: 113: 102: 99: 95: 92: 88: 85: 81: 78: 74: 71: â€“  70: 66: 65:Find sources: 59: 55: 49: 48: 43:This article 41: 37: 32: 31: 19: 5034: 5022: 5010: 4998: 4848:Biosynthesis 4827: 4698:Geochemistry 4613:Pharmacology 4589:Cell biology 4579:Biochemistry 4407:Spectroscopy 4306:VSEPR theory 4155:Spectroscopy 4099:Branches of 4055: 4043: 4031: 3909:Biosynthesis 3879: 2791:Ene reaction 2151:Autoxidation 2012:Degradation 1903:Azo coupling 1680:Ugi reaction 1280:Ene reaction 1080:Alkynylation 931:Polyfluorene 926:Polar effect 791:Electrophile 706:Bredt's rule 676:Baird's rule 646:Alpha effect 497: 492: 486: 477: 471: 442: 438: 428: 409: 363: 344:Biosynthesis 312: 280: 277:biochemistry 244: 238: 224: 218: 200: 198: 184:or a simple 173: 167: 161: 157:reproducible 136: 132: 131: 116: 107: 97: 90: 83: 76: 64: 52:Please help 47:verification 44: 5036:WikiProject 4261:Theoretical 4246:Calorimetry 1290:Ethenolysis 936:Ring strain 906:Nucleophile 731:Clar's rule 671:Aromaticity 480:. Springer. 249:paracetamol 5052:Categories 4872:Metallurgy 4571:Biological 4137:Analytical 3574:Ozonolysis 3101:Annulation 2451:Ozonolysis 570:Topics in 500:(5): 728. 393:References 332:Also visit 288:. For the 235:Strategies 166:(known as 153:laboratory 110:March 2016 80:newspapers 5063:Chemistry 4934:Catalysis 4442:Inorganic 4236:Titration 4101:chemistry 3088:reactions 2603:reactions 2098:reactions 2014:reactions 1896:reactions 1038:reactions 459:0075-4617 315:cisplatin 305:process. 225:synthesis 174:reactants 164:compounds 5000:Category 4956:Molecule 4893:See also 4318:Physical 4033:Category 981:Vinylogy 651:Annulene 598:Reagents 463:Archived 241:reactant 169:reagents 149:physical 145:products 5012:Commons 4976:Alchemy 4492:Organic 4045:Commons 641:A value 502:Bibcode 190:work-up 94:scholar 5024:Portal 4170:UV-Vis 4057:Portal 457:  416:  192:") or 96:  89:  82:  75:  67:  4197:MALDI 4165:Raman 3959:LASiS 3887:Types 317:from 211:grams 101:JSTOR 87:books 4951:Atom 4219:HPLC 455:ISSN 414:ISBN 275:and 217:. A 207:mass 73:news 4961:Ion 4192:ICP 4175:NMR 510:doi 447:doi 209:in 172:or 56:by 5054:: 4691:/ 4687:/ 4539:/ 4214:GC 4187:EI 4160:IR 508:. 498:83 461:. 453:. 443:54 441:. 437:. 400:^ 321:. 297:a 231:. 4925:" 4921:" 4092:e 4085:t 4078:v 3872:e 3865:t 3858:v 563:e 556:t 549:v 516:. 512:: 504:: 449:: 422:. 135:( 123:) 117:( 112:) 108:( 98:· 91:· 84:· 77:· 50:. 20:)

Index

Multistep synthesis

verification
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"Chemical synthesis"
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scholar
JSTOR
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chemical reactions
products
physical
laboratory
reproducible
compounds
reagents
Various reaction types
chemical reactor
round-bottom flask
work-up
purification procedure
reaction yield
mass
grams
limiting reagent
side reaction
Hermann Kolbe

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