84:
60:
576:
Raza, A; Reeves, J. A.; Feldman, E. J.; Dewald, G. W.; Bennett, J. M.; Deeg, H. J.; Dreisbach, L; Schiffer, C. A.; Stone, R. M.; Greenberg, P. L.; Curtin, P. T.; Klimek, V. M.; Shammo, J. M.; Thomas, D; Knight, R. D.; Schmidt, M; Wride, K; Zeldis, J. B.; List, A. F. (2008).
2182:
808:
694:
1662:
766:
2103:
1813:
1766:
1667:
217:
1591:
1962:
579:"Phase 2 study of lenalidomide in transfusion-dependent, low-risk, and intermediate-1 risk myelodysplastic syndromes with karyotypes other than deletion 5q"
2315:
1672:
1335:
275:(MDS) associated with chromosome 5q deletion with or without additional cytogenetic abnormalities. There are several possible mechanisms that link the
618:
Voutsadakis IA; Cairoli A (2012). "A critical review of the molecular pathophysiology of lenalidomide sensitivity in 5q – myelodysplastic syndromes".
477:
Starczynowski DT; Kuchenbauer F; Argiropoulos B (January 2010). "Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype".
2083:
759:
17:
1739:
2248:
2098:
1448:
705:
519:
2320:
752:
1438:
295:
Lazjuk GI; Lurie IW; Kirillova IA; et al. (August 1985). "Partial trisomy 5q and partial monosomy 5q within the same family".
1823:
1584:
1021:
2310:
1999:
1828:
1420:
1363:
256:. They are more numerous than usual, small and mononuclear. There may be accompanying erythroid hypoplasia in the bone marrow.
2172:
1414:
1353:
1291:
153:, and an isolated interstitial deletion of chromosome 5. The 5q- syndrome is found predominantly in females of advanced age.
340:
Chapter 8 - Myelodysplastic
Syndromes in Hematopathology Morphology, Immunophenotype, Cytogenetics and Molecular Approaches
1940:
1801:
1699:
908:
667:
937:
2280:
2215:
1751:
1677:
1357:
1349:
1305:
997:
872:
850:
2265:
2046:
1982:
1930:
1918:
1689:
1657:
1577:
1548:
1536:
916:
803:
993:
989:
2305:
2177:
1944:
1295:
245:
1058:
1992:
1883:
1462:
1424:
1223:
119:
5q", though both conditions have been observed in the same family. Diagnosis is achieved through marrow biopsy.
2068:
2034:
1734:
1604:
912:
716:
272:
241:
109:
362:
1761:
1478:
1470:
1456:
1442:
1400:
1321:
1033:
2238:
2024:
1908:
1873:
1791:
1724:
1647:
924:
775:
271:
approved for red blood cell (RBC) transfusion-dependent anemia due to low or intermediate-1 (int-1) risk
2275:
1552:
186:
136:
1532:
1528:
2197:
2187:
2093:
1279:
1204:
1143:
949:
377:
1452:
1265:
899:
83:
67:
Photomicrograph of bone marrow showing abnormal mononuclear megakaryocytes typical of 5q- syndrome
2142:
1556:
1544:
1540:
1504:
1499:
1434:
1048:
828:
643:
502:
320:
276:
170:
2192:
2147:
2056:
1518:
1135:
1054:
1009:
977:
965:
727:
635:
600:
558:
494:
459:
403:
312:
212:, which has antiproliferative and antiangiogenic effects; and the candidate tumor suppressors
128:
72:
1513:
1509:
1406:
1283:
1251:
882:
627:
590:
548:
486:
449:
441:
393:
385:
343:
304:
1569:
2253:
1523:
1112:
663:
59:
381:
1197:
1163:
1158:
833:
699:
454:
429:
398:
347:
308:
253:
205:
132:
96:
is an acquired, hematological disorder characterized by loss of part of the long arm (
2299:
1848:
1780:
1392:
1192:
1153:
1148:
1076:
1062:
1038:
1026:
1014:
1002:
982:
887:
865:
860:
838:
198:
140:
647:
324:
2163:
2152:
1187:
1094:
1090:
970:
958:
942:
930:
920:
823:
671:
506:
264:
166:
147:
101:
721:
631:
595:
578:
2132:
1618:
1209:
1180:
1175:
1072:
249:
233:
209:
143:
18:
Myelodysplastic syndrome associated with isolated del(5q) chromosome abnormality
732:
1329:
1325:
1131:
877:
855:
845:
77:
1636:
1170:
1126:
818:
813:
201:
105:
744:
639:
604:
562:
498:
463:
407:
363:"Identification of RPS14 as a 5q- syndrome gene by RNA interference screen"
537:"Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion"
316:
2121:
1862:
1713:
1286:
1236:
1232:
1104:
783:
553:
536:
194:
150:
46:
445:
389:
108:
cells. This chromosome abnormality is most commonly associated with the
1971:
1897:
1600:
1339:
1122:
795:
190:
116:
686:
2078:
1627:
1612:
237:
221:
178:
490:
2013:
1428:
1367:
1343:
1273:
174:
97:
1474:
1466:
1410:
1396:
1371:
1299:
1269:
1259:
710:
523:
213:
162:
1573:
748:
1255:
268:
182:
2183:
Adult type of generalized eruption of cutaneous mastocytosis
338:
Naeim, Faramarz; Rao, P. Nagesh; W. Grody, Wayne (2008).
676:
2262:
2235:
2228:
2206:
2161:
2129:
2120:
2065:
2043:
2021:
2012:
1979:
1970:
1961:
1927:
1905:
1896:
1870:
1861:
1841:
1810:
1788:
1779:
1748:
1721:
1712:
1686:
1644:
1635:
1626:
1611:
1492:
1385:
1314:
1244:
1231:
1222:
1121:
1103:
1089:
898:
791:
782:
680:
165:in the deleted region appear to play a role in the
71:
40:
35:
279:molecular lesions with lenalidomide sensitivity.
2104:Refractory cytopenia with multilineage dysplasia
1767:Accelerated phase chronic myelogenous leukemia
1585:
1514:46,XX testicular disorders of sex development
760:
177:plays a central role, and contributes to the
8:
535:List A; Dewald G; Bennett J (October 2006).
423:
421:
419:
417:
189:effects. Other genes at this region include
1336:Acute myeloblastic leukemia with maturation
434:Clinical Medicine Insights: Blood Disorders
361:Ebert BL; Pretz J; Bosco J (January 2008).
2232:
2126:
2018:
1976:
1967:
1902:
1867:
1785:
1718:
1641:
1632:
1623:
1592:
1578:
1570:
1241:
1228:
1100:
788:
767:
753:
745:
677:
82:
58:
32:
594:
552:
453:
397:
430:"Ribosomopathies: Mechanisms of disease"
197:, whose deletion is associated with the
115:It should not be confused with "partial
2084:Refractory anemia with excess of blasts
287:
7:
2249:Acute panmyelosis with myelofibrosis
267:has activity in 5q- syndrome and is
252:shows characteristic changes in the
127:The 5q-syndrome is characterized by
2099:Paroxysmal nocturnal hemoglobinuria
1449:Desmoplastic small-round-cell tumor
520:Online Mendelian Inheritance in Man
2316:Autosomal monosomies and deletions
348:10.1016/B978-0-12-370607-2.00008-9
309:10.1111/j.1399-0004.1985.tb00371.x
236:cells causing treatment-resistant
25:
1824:Juvenile myelomonocytic leukemia
1022:22q11.2 distal deletion syndrome
428:Nakhoul H, Ke J, Zhou X (2014).
2089:Chromosome 5q deletion syndrome
2000:Acute megakaryoblastic leukemia
1829:Chronic myelomonocytic leukemia
1740:Myeloid dendritic cell leukemia
1421:Dermatofibrosarcoma protuberans
1364:Acute megakaryoblastic leukemia
1292:Anaplastic large-cell lymphoma
954:Chromosome 5q deletion syndrome
185:-dependent and p53-independent
94:Chromosome 5q deletion syndrome
36:Chromosome 5q deletion syndrome
2173:Diffuse cutaneous mastocytosis
1:
1941:Chronic eosinophilic leukemia
1700:Chronic neutrophilic leukemia
1144:Klinefelter syndrome (47,XXY)
909:1q21.1 copy number variations
2281:Biphenotypic acute leukaemia
2216:Xanthelasmoidal mastocytosis
1350:Acute promyelocytic leukemia
1306:Acute lymphoblastic leukemia
998:17q12 microdeletion syndrome
873:22q11.2 duplication syndrome
851:16p11.2 duplication syndrome
632:10.3109/10428194.2011.623255
596:10.1182/blood-2007-01-068833
1658:Acute myeloblastic leukemia
917:1q21.1 duplication syndrome
804:1q21.1 duplication syndrome
2337:
2178:Erythrodermic mastocytosis
1945:Hypereosinophilic syndrome
246:acute myelogenous leukemia
2321:Syndromes affecting blood
1993:Essential thrombocythemia
1463:Alveolar rhabdomyosarcoma
1198:XYYYY syndrome (49,XYYYY)
1164:XXXXY syndrome (49,XXXXY)
1159:XXXYY syndrome (49,XXXYY)
242:myelodysplastic syndromes
66:
57:
1605:hematological malignancy
938:Wolf–Hirschhorn syndrome
913:1q21.1 deletion syndrome
776:Chromosome abnormalities
273:myelodysplastic syndrome
110:myelodysplastic syndrome
100:, band 5q33.1) of human
1762:Philadelphia chromosome
1322:Philadelphia chromosome
1193:XYYY syndrome (48,XYYY)
1154:XXXY syndrome (48,XXXY)
1149:XXYY syndrome (48,XXYY)
1034:22q13 deletion syndrome
809:2q31.1 microduplication
620:Leukemia & Lymphoma
2311:Rare genetic syndromes
1181:Pentasomy X (49,XXXXX)
1113:Turner syndrome (45,X)
994:Smith–Magenis syndrome
990:Miller–Dieker syndrome
925:1p36 deletion syndrome
232:This syndrome affects
208:seen in 5q- syndrome;
2276:Primary myelofibrosis
2208:Systemic mastocytosis
2153:Systemic mastocytosis
1188:XYY syndrome (47,XYY)
1176:Tetrasomy X (48,XXXX)
1059:Prader–Willi syndrome
524:5q- syndrome - 153550
248:. Examination of the
2198:Solitary mastocytoma
2188:Urticaria pigmentosa
2094:Sideroblastic anemia
1280:Mantle cell lymphoma
950:Cri du chat syndrome
554:10.1056/NEJMoa061292
342:. pp. 129–154.
1266:Follicular lymphoma
446:10.4137/CMBD.S16952
390:10.1038/nature06494
382:2008Natur.451..335E
131:, often a moderate
2143:Mast cell leukemia
2035:Erythroleukemia/M6
1919:Acute eosinophilic
1505:Uniparental disomy
1500:Fragile X syndrome
1435:Myxoid liposarcoma
1287:t(11 CCND1:14 IGH)
1171:Trisomy X (47,XXX)
1049:genomic imprinting
829:Distal trisomy 10q
277:haploinsufficiency
171:Haploinsufficiency
137:erythroblastopenia
2306:Myeloid neoplasia
2293:
2292:
2289:
2288:
2224:
2223:
2193:Mast cell sarcoma
2148:Mast cell sarcoma
2116:
2115:
2112:
2111:
2079:Refractory anemia
2057:Polycythemia vera
2008:
2007:
1957:
1956:
1953:
1952:
1892:
1891:
1857:
1856:
1837:
1836:
1775:
1774:
1708:
1707:
1567:
1566:
1519:Marker chromosome
1488:
1487:
1381:
1380:
1218:
1217:
1085:
1084:
1055:Angelman syndrome
1010:DiGeorge syndrome
978:Jacobsen syndrome
966:Williams syndrome
742:
741:
244:that may lead to
129:macrocytic anemia
91:
90:
30:Medical condition
16:(Redirected from
2328:
2269:
2242:
2233:
2229:Multiple/unknown
2209:
2166:
2136:
2127:
2072:
2050:
2028:
2019:
1986:
1977:
1968:
1934:
1912:
1903:
1884:Acute basophilic
1877:
1868:
1817:
1795:
1786:
1755:
1728:
1719:
1693:
1651:
1642:
1633:
1624:
1594:
1587:
1580:
1571:
1510:XX male syndrome
1407:Synovial sarcoma
1284:Multiple myeloma
1252:Burkitt lymphoma
1242:
1229:
1132:other karyotypes
1101:
883:Cat-eye syndrome
789:
769:
762:
755:
746:
678:
652:
651:
615:
609:
608:
598:
573:
567:
566:
556:
532:
526:
517:
511:
510:
474:
468:
467:
457:
425:
412:
411:
401:
367:
358:
352:
351:
335:
329:
328:
292:
187:tumor suppressor
169:of 5q-syndrome.
87:
86:
62:
33:
21:
2336:
2335:
2331:
2330:
2329:
2327:
2326:
2325:
2296:
2295:
2294:
2285:
2263:
2258:
2254:Myeloid sarcoma
2236:
2220:
2207:
2202:
2162:
2157:
2130:
2108:
2066:
2061:
2044:
2039:
2022:
2004:
1980:
1949:
1928:
1923:
1906:
1888:
1871:
1853:
1833:
1811:
1806:
1789:
1771:
1749:
1744:
1722:
1704:
1687:
1682:
1645:
1616:
1607:
1598:
1568:
1563:
1524:Ring chromosome
1484:
1377:
1310:
1214:
1130:
1117:
1081:
894:
793:
778:
773:
743:
738:
737:
689:
660:
655:
617:
616:
612:
575:
574:
570:
547:(14): 1456–65.
541:N. Engl. J. Med
534:
533:
529:
518:
514:
491:10.1038/nm.2054
479:Nature Medicine
476:
475:
471:
427:
426:
415:
376:(7176): 335–9.
365:
360:
359:
355:
337:
336:
332:
294:
293:
289:
285:
262:
230:
159:
125:
104:in bone marrow
81:
31:
28:
23:
22:
15:
12:
11:
5:
2334:
2332:
2324:
2323:
2318:
2313:
2308:
2298:
2297:
2291:
2290:
2287:
2286:
2284:
2283:
2278:
2272:
2270:
2260:
2259:
2257:
2256:
2251:
2245:
2243:
2230:
2226:
2225:
2222:
2221:
2219:
2218:
2212:
2210:
2204:
2203:
2201:
2200:
2195:
2190:
2185:
2180:
2175:
2169:
2167:
2159:
2158:
2156:
2155:
2150:
2145:
2139:
2137:
2124:
2118:
2117:
2114:
2113:
2110:
2109:
2107:
2106:
2101:
2096:
2091:
2086:
2081:
2075:
2073:
2063:
2062:
2060:
2059:
2053:
2051:
2041:
2040:
2038:
2037:
2031:
2029:
2016:
2010:
2009:
2006:
2005:
2003:
2002:
1996:
1995:
1989:
1987:
1974:
1965:
1959:
1958:
1955:
1954:
1951:
1950:
1948:
1947:
1937:
1935:
1925:
1924:
1922:
1921:
1915:
1913:
1900:
1894:
1893:
1890:
1889:
1887:
1886:
1880:
1878:
1865:
1859:
1858:
1855:
1854:
1852:
1851:
1845:
1843:
1839:
1838:
1835:
1834:
1832:
1831:
1826:
1820:
1818:
1808:
1807:
1805:
1804:
1798:
1796:
1783:
1777:
1776:
1773:
1772:
1770:
1769:
1764:
1758:
1756:
1746:
1745:
1743:
1742:
1737:
1731:
1729:
1716:
1710:
1709:
1706:
1705:
1703:
1702:
1696:
1694:
1684:
1683:
1681:
1680:
1675:
1670:
1665:
1660:
1654:
1652:
1639:
1630:
1621:
1609:
1608:
1599:
1597:
1596:
1589:
1582:
1574:
1565:
1564:
1562:
1561:
1560:
1559:
1521:
1516:
1507:
1502:
1496:
1494:
1490:
1489:
1486:
1485:
1483:
1482:
1460:
1446:
1432:
1418:
1404:
1389:
1387:
1383:
1382:
1379:
1378:
1376:
1375:
1361:
1347:
1333:
1318:
1316:
1312:
1311:
1309:
1308:
1303:
1289:
1277:
1263:
1248:
1246:
1239:
1226:
1224:Translocations
1220:
1219:
1216:
1215:
1213:
1212:
1207:
1201:
1200:
1195:
1190:
1184:
1183:
1178:
1173:
1167:
1166:
1161:
1156:
1151:
1146:
1140:
1138:
1119:
1118:
1116:
1115:
1109:
1107:
1098:
1087:
1086:
1083:
1082:
1080:
1079:
1069:
1068:
1067:
1066:
1044:
1043:
1042:
1041:
1031:
1030:
1029:
1019:
1018:
1017:
1007:
1006:
1005:
987:
986:
985:
975:
974:
973:
963:
962:
961:
947:
946:
945:
935:
934:
933:
904:
902:
896:
895:
893:
892:
891:
890:
880:
875:
870:
869:
868:
858:
853:
848:
843:
842:
841:
834:Patau syndrome
831:
826:
821:
816:
811:
806:
800:
798:
786:
780:
779:
774:
772:
771:
764:
757:
749:
740:
739:
736:
735:
724:
713:
702:
690:
685:
684:
682:
681:Classification
675:
674:
659:
658:External links
656:
654:
653:
610:
568:
527:
512:
469:
413:
353:
330:
286:
284:
281:
261:
258:
254:megakaryocytes
229:
226:
206:thrombocytosis
199:megakaryocytic
158:
155:
133:thrombocytosis
124:
121:
89:
88:
75:
69:
68:
64:
63:
55:
54:
45:Chromosome 5q
42:
38:
37:
29:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
2333:
2322:
2319:
2317:
2314:
2312:
2309:
2307:
2304:
2303:
2301:
2282:
2279:
2277:
2274:
2273:
2271:
2268:
2267:
2261:
2255:
2252:
2250:
2247:
2246:
2244:
2241:
2240:
2234:
2231:
2227:
2217:
2214:
2213:
2211:
2205:
2199:
2196:
2194:
2191:
2189:
2186:
2184:
2181:
2179:
2176:
2174:
2171:
2170:
2168:
2165:
2160:
2154:
2151:
2149:
2146:
2144:
2141:
2140:
2138:
2135:
2134:
2128:
2125:
2123:
2119:
2105:
2102:
2100:
2097:
2095:
2092:
2090:
2087:
2085:
2082:
2080:
2077:
2076:
2074:
2071:
2070:
2064:
2058:
2055:
2054:
2052:
2049:
2048:
2042:
2036:
2033:
2032:
2030:
2027:
2026:
2020:
2017:
2015:
2011:
2001:
1998:
1997:
1994:
1991:
1990:
1988:
1985:
1984:
1978:
1975:
1973:
1969:
1966:
1964:
1960:
1946:
1942:
1939:
1938:
1936:
1933:
1932:
1926:
1920:
1917:
1916:
1914:
1911:
1910:
1904:
1901:
1899:
1895:
1885:
1882:
1881:
1879:
1876:
1875:
1869:
1866:
1864:
1860:
1850:
1849:Histiocytosis
1847:
1846:
1844:
1840:
1830:
1827:
1825:
1822:
1821:
1819:
1816:
1815:
1809:
1803:
1800:
1799:
1797:
1794:
1793:
1787:
1784:
1782:
1781:Myelomonocyte
1778:
1768:
1765:
1763:
1760:
1759:
1757:
1754:
1753:
1747:
1741:
1738:
1736:
1733:
1732:
1730:
1727:
1726:
1720:
1717:
1715:
1711:
1701:
1698:
1697:
1695:
1692:
1691:
1685:
1679:
1676:
1674:
1671:
1669:
1666:
1664:
1661:
1659:
1656:
1655:
1653:
1650:
1649:
1643:
1640:
1638:
1634:
1631:
1629:
1625:
1622:
1620:
1614:
1610:
1606:
1602:
1595:
1590:
1588:
1583:
1581:
1576:
1575:
1572:
1558:
1554:
1550:
1546:
1542:
1538:
1534:
1530:
1527:
1526:
1525:
1522:
1520:
1517:
1515:
1511:
1508:
1506:
1503:
1501:
1498:
1497:
1495:
1491:
1480:
1476:
1472:
1468:
1464:
1461:
1458:
1454:
1450:
1447:
1444:
1440:
1436:
1433:
1430:
1426:
1422:
1419:
1416:
1412:
1408:
1405:
1402:
1398:
1394:
1393:Ewing sarcoma
1391:
1390:
1388:
1384:
1373:
1369:
1365:
1362:
1359:
1355:
1351:
1348:
1345:
1341:
1337:
1334:
1331:
1327:
1323:
1320:
1319:
1317:
1313:
1307:
1304:
1301:
1297:
1293:
1290:
1288:
1285:
1281:
1278:
1275:
1271:
1267:
1264:
1261:
1257:
1253:
1250:
1249:
1247:
1243:
1240:
1238:
1234:
1230:
1227:
1225:
1221:
1211:
1208:
1206:
1203:
1202:
1199:
1196:
1194:
1191:
1189:
1186:
1185:
1182:
1179:
1177:
1174:
1172:
1169:
1168:
1165:
1162:
1160:
1157:
1155:
1152:
1150:
1147:
1145:
1142:
1141:
1139:
1137:
1133:
1128:
1124:
1120:
1114:
1111:
1110:
1108:
1106:
1102:
1099:
1096:
1092:
1088:
1078:
1077:Proximal 18q-
1074:
1071:
1070:
1064:
1060:
1056:
1053:
1052:
1051:
1050:
1046:
1045:
1040:
1037:
1036:
1035:
1032:
1028:
1025:
1024:
1023:
1020:
1016:
1013:
1012:
1011:
1008:
1004:
1001:
1000:
999:
995:
991:
988:
984:
981:
980:
979:
976:
972:
969:
968:
967:
964:
960:
957:
956:
955:
951:
948:
944:
941:
940:
939:
936:
932:
929:
928:
926:
922:
918:
914:
910:
906:
905:
903:
901:
897:
889:
886:
885:
884:
881:
879:
876:
874:
871:
867:
864:
863:
862:
861:Down syndrome
859:
857:
854:
852:
849:
847:
844:
840:
837:
836:
835:
832:
830:
827:
825:
822:
820:
817:
815:
812:
810:
807:
805:
802:
801:
799:
797:
792:Duplications,
790:
787:
785:
781:
777:
770:
765:
763:
758:
756:
751:
750:
747:
734:
730:
729:
725:
723:
719:
718:
714:
712:
708:
707:
703:
701:
697:
696:
692:
691:
688:
683:
679:
673:
672:Rare Diseases
670:'s Office of
669:
665:
662:
661:
657:
649:
645:
641:
637:
633:
629:
626:(5): 779–88.
625:
621:
614:
611:
606:
602:
597:
592:
588:
584:
580:
572:
569:
564:
560:
555:
550:
546:
542:
538:
531:
528:
525:
521:
516:
513:
508:
504:
500:
496:
492:
488:
484:
480:
473:
470:
465:
461:
456:
451:
447:
443:
439:
435:
431:
424:
422:
420:
418:
414:
409:
405:
400:
395:
391:
387:
383:
379:
375:
371:
364:
357:
354:
349:
345:
341:
334:
331:
326:
322:
318:
314:
310:
306:
302:
298:
291:
288:
282:
280:
278:
274:
270:
266:
259:
257:
255:
251:
247:
243:
239:
235:
227:
225:
223:
219:
215:
211:
207:
203:
200:
196:
192:
188:
184:
180:
176:
172:
168:
164:
156:
154:
152:
149:
145:
142:
141:megakaryocyte
138:
134:
130:
122:
120:
118:
113:
111:
107:
103:
99:
95:
85:
79:
76:
74:
70:
65:
61:
56:
53:
49:
48:
43:
39:
34:
27:Human disease
19:
2264:
2237:
2164:Mastocytosis
2131:
2088:
2067:
2045:
2023:
1981:
1929:
1907:
1872:
1812:
1790:
1750:
1723:
1688:
1646:
1619:granulocytes
1047:
953:
921:TAR syndrome
824:Tetrasomy 9p
726:
715:
704:
693:
664:5q- syndrome
623:
619:
613:
589:(1): 86–93.
586:
582:
571:
544:
540:
530:
515:
485:(1): 49–58.
482:
478:
472:
437:
433:
373:
369:
356:
339:
333:
303:(2): 122–9.
300:
296:
290:
265:Lenalidomide
263:
231:
167:pathogenesis
160:
151:hypolobation
126:
123:Presentation
114:
102:chromosome 5
93:
92:
52:5q- syndrome
51:
44:
2133:Mastocytoma
1210:46,XX/46,XY
1127:tetrasomies
1073:Distal 18q-
297:Clin. Genet
250:bone marrow
234:bone marrow
144:hyperplasia
41:Other names
2300:Categories
1617:and other
1205:45,X/46,XY
1105:Monosomies
878:Trisomy 22
856:Trisomy 18
846:Trisomy 16
794:including
728:DiseasesDB
283:References
78:Hematology
1637:Myelocyte
1603:-related
1123:Trisomies
900:Deletions
819:Trisomy 9
814:Trisomy 8
796:trisomies
784:Autosomal
260:Treatment
228:Histology
202:dysplasia
181:via both
106:myelocyte
73:Specialty
2122:CFU-Mast
1863:CFU-Baso
1714:Monocyte
1245:Lymphoid
1237:lymphoma
1233:Leukemia
648:38251104
640:21955212
605:17893227
563:17021321
522:(OMIM):
499:19898489
464:25512719
440:: 7–16.
408:18202658
325:33815922
195:miR-146a
161:Several
47:monosomy
1972:CFU-Meg
1898:CFU-Eos
1735:AMoL/M5
1601:Myeloid
1473:) t (1
1340:RUNX1T1
1315:Myeloid
1136:mosaics
722:C535323
700:M9986/3
507:7987486
455:4251057
399:3771855
378:Bibcode
317:4042393
191:miR-145
148:nuclear
117:trisomy
1678:APL/M3
1628:CFU-GM
1613:CFU-GM
1425:COL1A1
1097:linked
711:153550
646:
638:
603:
561:
505:
497:
462:
452:
406:
396:
370:Nature
323:
315:
238:anemia
222:CDC25C
220:, and
218:CTNNA1
179:anemia
157:Causes
80:
2014:CFU-E
1842:Other
1814:MD-MP
1493:Other
1479:FOXO1
1477:; 13
1471:FOXO1
1469:; 13
1455:; 22
1451:t(11
1441:; 16
1439:DDIT3
1437:t(12
1429:PDGFB
1423:t(17
1399:; 22
1395:t(11
1386:Other
1368:RBM15
1352:t(15
1344:RUNX1
1328:; 22
1268:t(14
733:34573
695:ICD-O
644:S2CID
583:Blood
503:S2CID
366:(PDF)
321:S2CID
210:SPARC
175:RPS14
163:genes
146:with
98:q arm
1475:PAX7
1467:PAX3
1465:t(2
1427:;22
1413:;18
1409:t(x
1397:FLI1
1372:MKL1
1370:;22
1366:t(1
1358:RARA
1356:,17
1342:;21
1338:t(8
1324:t(9
1300:NPM1
1294:t(2
1274:BCL2
1272:;18
1258:;14
1254:t(8
717:MeSH
706:OMIM
636:PMID
601:PMID
559:PMID
495:PMID
460:PMID
404:PMID
313:PMID
240:and
214:EGR1
204:and
193:and
2239:AML
2025:AML
1963:MEP
1909:AML
1874:AML
1792:AML
1752:CML
1725:AML
1648:AML
1457:EWS
1453:WT1
1443:FUS
1415:SSX
1411:SYT
1401:EWS
1354:PML
1330:BCR
1326:ABL
1298:;5
1296:ALK
1270:IGH
1260:IGH
1256:MYC
668:NIH
666:at
628:doi
591:doi
587:111
549:doi
545:355
487:doi
450:PMC
442:doi
394:PMC
386:doi
374:451
344:doi
305:doi
269:FDA
183:p53
173:of
2302::
2266:MP
2069:MD
2047:MP
1983:MP
1931:MP
1802:M4
1690:MP
1673:M2
1668:M1
1663:M0
1557:22
1555:,
1553:21
1551:;
1549:20
1547:;
1545:18
1543:;
1541:15
1539:;
1537:14
1535:;
1531:;
1063:15
1039:22
1027:22
1015:22
1003:17
983:11
927:)
888:22
866:21
839:13
731::
720::
709::
698::
642:.
634:.
624:53
622:.
599:.
585:.
581:.
557:.
543:.
539:.
501:.
493:.
483:16
481:.
458:.
448:.
436:.
432:.
416:^
402:.
392:.
384:.
372:.
368:.
319:.
311:.
301:28
299:.
224:.
216:,
139:,
135:,
112:.
50:,
1943:/
1615:/
1593:e
1586:t
1579:v
1533:9
1529:6
1512:/
1481:)
1459:)
1445:)
1431:)
1417:)
1403:)
1374:)
1360:)
1346:)
1332:)
1302:)
1282:/
1276:)
1262:)
1235:/
1134:/
1129:,
1125:/
1095:Y
1093:/
1091:X
1075:/
1065:)
1061:(
1057:/
996:/
992:/
971:7
959:5
952:/
943:4
931:1
923:/
919:/
915:/
911:/
907:(
768:e
761:t
754:v
687:D
650:.
630::
607:.
593::
565:.
551::
509:.
489::
466:.
444::
438:7
410:.
388::
380::
350:.
346::
327:.
307::
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
