329:
306:
203:
228:
2996:
2966:
2981:
580:
3026:
3011:
335:
234:
40:
1470:
and the dynamics of the SVs on the actin filaments. The absence of MYO5A in the brain can be associated with loco motor dysfunction and neuroendocrine abnormalities. As mention MYO5A is highly expressed on the neurons. Therefore, a mutation on MYO5A can be related with abnormal neuronal development
1401:
In the presence of cargo adapters and calcium, unconventional myosin Va is present in an elongated and active state. It has an N-terminal head domain and a C-terminal tail domain. The actin-binding head (N-Terminal) is an ATP-dependent motor domain that transmits changes from the active site to the
2129:
Assis, L. H. P.; Silva-Junior, R. M. P.; Dolce, L. G.; Alborghetti, M. R.; Honorato, R. V.; Nascimento, A. F. Z.; Melo-Hanchuk, T. D.; Trindade, D. M.; Tonoli, C. C. C.; Santos, C. T.; Oliveira, P. S. L.; Larson, R. E.; Kobarg, J.; Espreafico, E. M.; Giuseppe, P. O.; Murakami, M. T. (2017).
66:
2246:
Pastural E, Barrat FJ, Dufourcq-Lagelouse R, Certain S, Sanal O, Jabado N, Seger R, Griscelli C, Fischer A, de Saint Basile G (Jul 1997). "Griscelli disease maps to chromosome 15q21 and is associated with mutations in the myosin-Va gene".
2184:
1402:
light chain lever arm. The C-terminal globular domain (GB) decides the Myosin class and moderate the cargo transport. Also, the GB interacts with other cargo specific proteins. Myosin Va is highly expressed in neurons and melanocytes.
2077:
Puthalakath H, Villunger A, O'Reilly LA, Beaumont JG, Coultas L, Cheney RE, Huang DC, Strasser A (Sep 2001). "Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis".
2483:
Pastural E, Ersoy F, Yalman N, Wulffraat N, Grillo E, Ozkinay F, Tezcan I, Gediköglu G, Philippe N, Fischer A, de Saint Basile G (Feb 2000). "Two genes are responsible for
Griscelli syndrome at the same 15q21 locus".
1744:
Schumacher-Bass, Sarah M.; Vesely, Eileen D.; Zhang, Lian; Ryland, Katherine E.; McEwen, Dyke P.; Chan, Priscilla J.; Frasier, Chad R.; McIntyre, Jeremy C.; Shaw, Robin M.; Martens, Jeffrey R. (2014-03-14).
2319:"The localization of myosin VI at the golgi complex and leading edge of fibroblasts and its phosphorylation and recruitment into membrane ruffles of A431 cells after growth factor stimulation"
1458:
Myosin Va is highly expressed in the nervous system and it is present in almost the entire brain. MY5A perform an important role in the regulation of axonal vesicle transport on the
2995:
1486:) in the myocytes. Kv1.5 is associated with the regulation of the action potential in the myocytes. New strategies targeting Kv1.5 current through MYO5A and MYO5B in human
2630:"Molecular cloning and characterization of neural activity-related RING finger protein (NARF): a new member of the RBCC family is a candidate for the partner of myosin V"
2965:
342:
241:
2980:
1682:
Wöllert, Torsten; Patel, Anamika; Lee, Ying-Lung; Provance, D. William; Vought, Valarie E.; Cosgrove, Michael S.; Mercer, John A.; Langford, George M. (2011-04-22).
3066:
1088:
164:
1069:
3025:
3010:
1386:
in charge of the intracellular transport of vesicles, organelles and protein complexes along the actin filaments. In humans it is coded for by the
5381:
2945:
1585:
3694:
1567:
2665:"Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport"
2550:"Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein"
1932:"Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein"
3059:
328:
2809:
Anikster Y, Huizing M, Anderson PD, Fitzpatrick DL, Klar A, Gross-Kieselstein E, Berkun Y, Shazberg G, Gahl WA, Hurvitz H (Aug 2002).
1320:
1451:
transport producing partial albinism. Griscelli syndrome type 1 can present with pigment defects and neurological disorders such as,
1327:
305:
1747:"A Role for Myosin V Motor Proteins in the Selective Delivery of Kv Channel Isoforms to the Membrane Surface of Cardiac Myocytes"
1447:
a rare autosomal recessive disorder. This defect is due a mutation in which a premature stop codon in the globular tail disrupt
4213:
1554:
1533:
5386:
4482:
4325:
3052:
227:
202:
1550:
63:
5361:
4915:
1529:
2395:
Mehta AD, Rock RS, Rief M, Spudich JA, Mooseker MS, Cheney RE (Aug 1999). "Myosin-V is a processive actin-based motor".
144:
3622:
1411:
341:
240:
5093:
334:
233:
2938:
1829:"Cloning, analysis, and chromosomal localization of myoxin (MYH12), the human homologue to the mouse dilute gene"
5326:
2442:"Inhibition of dendrite formation in mouse melanocytes transiently transfected with antisense DNA to myosin Va"
1133:
152:
2733:"A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transport"
2811:"Evidence that Griscelli syndrome with neurological involvement is caused by mutations in RAB27A, not MYO5A"
1870:"Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types"
1114:
2515:"arg-cys substitution at codon 1246 of the human myosin Va gene is not associated with Griscelli syndrome"
2215:"Cloning and regional assignment of the human myosin heavy chain 12 (MYH12) gene to chromosome band 15q21"
3745:
3099:
216:
1462:. The GB of MYO5A can form a complex with Rab3A. The involvement of this complex is important for the
4014:
2931:
2865:
2404:
2143:
2087:
2041:
1881:
1621:
131:
5321:
3954:
1487:
1282:
1278:
1274:
1270:
1219:
1215:
1211:
1207:
2548:
Naisbitt S, Valtschanoff J, Allison DW, Sala C, Kim E, Craig AM, Weinberg RJ, Sheng M (Jun 2000).
1930:
Naisbitt S, Valtschanoff J, Allison DW, Sala C, Kim E, Craig AM, Weinberg RJ, Sheng M (Jun 2000).
3774:
3404:
2428:
2362:"Cloning and characterization of a novel RING finger protein that interacts with class V myosins"
2272:
2111:
1610:"Structural Insights into the Globular Tails of the Human Type V Myosins Myo5a, Myo5b, and Myo5c"
1440:
176:
1303:
1266:
1240:
1203:
5172:
4875:
3536:
2903:
2883:
2840:
2797:
2754:
2719:
2686:
2651:
2616:
2581:
2536:
2501:
2471:
2420:
2383:
2348:
2305:
2264:
2234:
2103:
2059:
2010:
1961:
1909:
1850:
1784:
1766:
1723:
1705:
1657:
1639:
1472:
1444:
124:
56:
4895:
5120:
4827:
4812:
4807:
4802:
4797:
4787:
4708:
4417:
4397:
4367:
4362:
4244:
3599:
3594:
2873:
2830:
2822:
2787:
2779:
2744:
2711:
2676:
2641:
2606:
2571:
2561:
2526:
2513:
Lambert J, Naeyaert JM, De Paepe A, Van Coster R, Ferster A, Song M, Messiaen L (Apr 2000).
2493:
2461:
2453:
2412:
2373:
2338:
2330:
2297:
2256:
2226:
2159:
2151:
2095:
2049:
2000:
1992:
1951:
1943:
1899:
1889:
1840:
1774:
1758:
1713:
1695:
1647:
1629:
1467:
1463:
421:
352:
296:
251:
5037:
5032:
5027:
5022:
4777:
4767:
4757:
4752:
4723:
4427:
4422:
3469:
3357:
3347:
3322:
3302:
3206:
3186:
2854:"Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions"
2030:"Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions"
579:
172:
5262:
3876:
3726:
3609:
3429:
2285:
1482:
are involved with Kv1.5 (encoded by
Potassium voltage-gated channel subfamily A member 5,
396:
3004:: CRYSTAL STRUCTURE OF MYOSIN V MOTOR WITH ESSENTIAL LIGHT CHAIN + ADP-BEFX - NEAR RIGOR
2869:
2457:
2408:
2147:
2091:
2045:
1885:
1625:
5225:
5088:
3785:
3616:
3125:
2576:
2566:
2549:
2466:
2441:
2343:
2318:
2164:
2131:
1956:
1947:
1931:
1779:
1746:
1718:
1683:
1652:
1609:
39:
2878:
2853:
2835:
2810:
2792:
2767:
2054:
2029:
2005:
1980:
1003:
998:
993:
988:
983:
978:
973:
968:
963:
958:
953:
948:
943:
938:
933:
928:
923:
918:
913:
908:
903:
898:
893:
888:
883:
878:
873:
868:
863:
858:
853:
837:
832:
827:
822:
817:
812:
807:
802:
797:
792:
787:
782:
777:
772:
767:
762:
757:
752:
747:
742:
737:
732:
727:
722:
717:
712:
707:
702:
697:
692:
676:
671:
666:
661:
656:
651:
646:
641:
636:
631:
626:
621:
5375:
5289:
5284:
4249:
4119:
4068:
4018:
3958:
3880:
3848:
3789:
3575:
3094:
2912:
2646:
2629:
2531:
2514:
2432:
2132:"The molecular motor Myosin Va interacts with the cilia-centrosomal protein RPGRIP1L"
1904:
1869:
1459:
1383:
854:
regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
608:
2276:
1803:"MYO5A - Unconventional myosin-Va - Homo sapiens (Human) - MYO5A gene & protein"
5133:
4188:
3943:
3487:
3079:
2852:
Nagashima K, Torii S, Yi Z, Igarashi M, Okamoto K, Takeuchi T, Izumi T (Apr 2002).
2595:"The 8-kDa dynein light chain binds to its targets via a conserved (K/R)XTQT motif"
2286:"Human myosin V gene produces different transcripts in a cell type-specific manner"
2115:
2028:
Nagashima K, Torii S, Yi Z, Igarashi M, Okamoto K, Takeuchi T, Izumi T (Apr 2002).
414:
193:
156:
5105:
5083:
2974:: CRYSTAL STRUCTURE OF MYOSIN V MOTOR WITH ESSENTIAL LIGHT CHAIN - NUCLEOTIDE-FREE
1762:
2317:
Buss F, Kendrick-Jones J, Lionne C, Knight AE, Côté GP, Paul Luzio J (Dec 1998).
1684:"Myosin5a Tail Associates Directly with Rab3A-containing Compartments in Neurons"
1634:
180:
5279:
5230:
5100:
4990:
4320:
3764:
3719:
3638:
3560:
3108:
1590:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1572:
National Center for
Biotechnology Information, U.S. National Library of Medicine
3044:
1874:
Proceedings of the
National Academy of Sciences of the United States of America
497:
5331:
5250:
5240:
5128:
4239:
4218:
3984:
3921:
3916:
3911:
3891:
3866:
3854:
3840:
3835:
3830:
3825:
3820:
3815:
3810:
3805:
3800:
3662:
3544:
3533:
3519:
3135:
2989:: CRYSTAL STRUCTURE OF MYOSIN V MOTOR WITHOUT NUCLEOTIDE SOAKED IN 10 MM MGADP
2699:
1448:
313:
210:
160:
2628:
Ohkawa N, Kokura K, Matsu-Ura T, Obinata T, Konishi Y, Tamura TA (Jul 2001).
2378:
2361:
2213:
Moore KJ, Testa JR, Francke U, Milatovich A, Copeland NG, Jenkins NA (1995).
1770:
1709:
1643:
5160:
5155:
5150:
5110:
4948:
4943:
4938:
4296:
4276:
3931:
3926:
3906:
3901:
3896:
3886:
3795:
3699:
3633:
2099:
1894:
1700:
1452:
1033:
557:
435:
380:
367:
279:
266:
168:
2887:
2844:
2801:
2783:
2758:
2749:
2732:
2723:
2690:
2681:
2664:
2655:
2620:
2611:
2594:
2585:
2540:
2505:
2497:
2475:
2424:
2387:
2334:
2301:
2107:
2063:
2014:
1996:
1965:
1845:
1828:
1788:
1727:
1661:
2715:
2352:
2309:
2268:
2238:
1913:
1854:
1367:
1362:
5274:
5235:
5167:
5140:
5007:
4995:
4870:
4865:
4306:
4301:
4223:
3657:
3652:
3514:
2700:"Human myosin-Vc is a novel class V myosin expressed in epithelial cells"
1802:
1351:
1178:
1159:
5301:
5255:
5145:
5075:
5044:
4974:
4969:
4933:
4928:
4923:
4890:
4860:
4855:
4850:
4845:
4530:
4462:
4457:
4452:
4447:
4442:
4334:
4271:
3759:
3704:
3645:
3628:
3589:
3075:
2917:
2907:
2768:"Rab27a is an essential component of melanosome receptor for myosin Va"
2260:
1981:"Rab27a is an essential component of melanosome receptor for myosin Va"
1145:
1100:
2284:
Lambert J, Naeyaert JM, Callens T, De Paepe A, Messiaen L (Nov 1998).
2230:
2155:
101:
97:
93:
89:
85:
5220:
5202:
5197:
5192:
5187:
5177:
5012:
4905:
4900:
4885:
4880:
4792:
4738:
4703:
4678:
4673:
4668:
4663:
4653:
4648:
4638:
4623:
4618:
4500:
4495:
4490:
4402:
4392:
4372:
4357:
4352:
4347:
4342:
4208:
3979:
3974:
3731:
3397:
3392:
3382:
3160:
1500:
1423:
1419:
1415:
1335:
1055:
17:
2731:
Strom M, Hume AN, Tarafder AK, Barkagianni E, Seabra MC (Jul 2002).
2214:
2826:
5245:
5017:
5000:
4837:
4832:
4822:
4817:
4782:
4772:
4762:
4747:
4728:
4718:
4713:
4698:
4693:
4688:
4683:
4658:
4643:
4633:
4628:
4613:
4608:
4588:
4583:
4578:
4573:
4568:
4563:
4558:
4553:
4548:
4543:
4538:
4510:
4505:
4472:
4467:
4437:
4432:
4412:
4407:
4387:
4377:
4292:
4170:
4165:
4160:
4155:
4150:
4145:
4140:
4135:
4130:
4125:
4109:
4104:
4099:
4094:
4089:
4084:
4079:
4074:
4049:
4044:
4039:
4034:
4029:
4024:
4004:
3999:
3994:
3989:
3969:
3964:
3674:
3604:
3553:
3550:
3547:
3539:
3528:
3525:
3522:
3507:
3502:
3497:
3492:
3464:
3454:
3439:
3372:
3362:
3342:
3317:
3312:
3297:
3287:
3282:
3277:
3272:
3267:
3262:
3247:
3201:
3196:
3191:
3181:
3176:
3171:
3150:
3145:
3140:
3130:
3117:
2416:
1868:
Bement WM, Hasson T, Wirth JA, Cheney RE, Mooseker MS (Jul 1994).
1505:
1483:
1479:
1427:
999:
establishment of endoplasmic reticulum localization to postsynapse
1018:
1014:
5346:
5341:
5336:
5296:
5267:
5182:
5059:
5054:
5049:
4953:
4603:
4598:
4593:
4520:
4515:
4382:
4264:
4259:
4254:
3714:
3709:
3667:
3580:
3570:
3565:
3459:
3449:
3444:
3434:
3424:
3419:
3414:
3409:
3332:
3257:
3252:
3242:
3237:
3232:
3227:
3222:
3217:
1390:
148:
3048:
2927:
588:
3034:: STRUCTURE OF APO-CALMODULIN BOUND TO UNCONVENTIONAL MYOSIN V
2923:
1004:
regulation of postsynaptic cytosolic calcium ion concentration
3019:: CRYSTAL STRUCTURE OF MYOSIN V MOTOR DOMAIN -NUCLEOTIDE-FREE
2902:
Overview of all the structural information available in the
2593:
Lo KW, Naisbitt S, Fan JS, Sheng M, Zhang M (Apr 2001).
404:
2766:
Wu X, Wang F, Rao K, Sellers JR, Hammer JA (May 2002).
1979:
Wu X, Wang F, Rao K, Sellers JR, Hammer JA (May 2002).
569:
5314:
5213:
5119:
5074:
4983:
4962:
4914:
4737:
4529:
4481:
4333:
4319:
4285:
4232:
4201:
4181:
4060:
3942:
3773:
3755:
3744:
3687:
3480:
3159:
3116:
3107:
3093:
3086:
2290:
1296:
1259:
1233:
1196:
1546:
1544:
1542:
1525:
1523:
1521:
351:
250:
1455:, motor development delay and mental impairment.
1925:
1923:
1608:Velvarska, Hana; Niessing, Dierk (2013-12-10).
27:Protein-coding gene in the species Homo sapiens
1551:GRCm38: Ensembl release 89: ENSMUSG00000034593
3060:
2939:
2663:Fukuda M, Kuroda TS, Mikoshiba K (Apr 2002).
8:
1530:GRCh38: Ensembl release 89: ENSG00000197535
4330:
3770:
3752:
3113:
3104:
3090:
3067:
3053:
3045:
2946:
2932:
2924:
1029:
964:locomotion involved in locomotory behavior
914:long-chain fatty acid biosynthetic process
604:
392:
291:
188:
74:
2877:
2834:
2791:
2748:
2680:
2645:
2610:
2575:
2565:
2530:
2465:
2377:
2342:
2163:
2053:
2004:
1955:
1903:
1893:
1844:
1778:
1717:
1699:
1651:
1633:
1439:Defects in Myosin Va are associated with
2519:The Journal of Investigative Dermatology
2961:
2360:El-Husseini AE, Vincent SR (Jul 1999).
1517:
954:protein localization to plasma membrane
929:vesicle transport along actin filament
29:
2179:
2177:
2175:
924:cellular response to insulin stimulus
889:post-Golgi vesicle-mediated transport
356:
317:
312:
255:
214:
209:
7:
2698:Rodriguez OC, Cheney RE (Mar 2002).
1739:
1737:
1677:
1675:
1673:
1671:
1603:
1601:
1599:
135:, GS1, MYH12, MYO5, MYR12, myosin VA
2737:The Journal of Biological Chemistry
2669:The Journal of Biological Chemistry
2599:The Journal of Biological Chemistry
2458:10.1046/j.1469-7580.1999.19520173.x
2366:The Journal of Biological Chemistry
1688:The Journal of Biological Chemistry
2916:(Unconventional myosin-Va) at the
2815:American Journal of Human Genetics
2567:10.1523/JNEUROSCI.20-12-04524.2000
1948:10.1523/JNEUROSCI.20-12-04524.2000
1293:
1256:
1230:
1193:
1169:
1150:
1124:
1105:
1079:
1060:
899:endoplasmic reticulum localization
662:disordered domain specific binding
574:
492:
430:
409:
25:
2440:Edgar AJ, Bennett JP (Aug 1999).
1827:Engle LJ, Kennett RH (Feb 1994).
446:lateral nuclear group of thalamus
3695:Wiskott–Aldrich syndrome protein
3024:
3009:
2994:
2979:
2964:
2647:10.1046/j.1471-4159.2001.00373.x
2532:10.1046/j.1523-1747.2000.00933.x
909:regulation of Golgi organization
578:
340:
333:
327:
304:
239:
232:
226:
201:
38:
4916:Microtubule organising proteins
2219:Cytogenetics and Cell Genetics
984:chemical synaptic transmission
874:secretory granule localization
743:insulin-responsive compartment
589:More reference expression data
558:More reference expression data
1:
4963:Microtubule severing proteins
2879:10.1016/S0014-5793(02)02634-0
2772:Molecular Biology of the Cell
2055:10.1016/S0014-5793(02)02634-0
1985:Molecular Biology of the Cell
1763:10.1161/CIRCRESAHA.114.302711
884:actin filament-based movement
823:unconventional myosin complex
325:
224:
5382:Genes on human chromosome 15
3623:actin depolymerizing factors
1635:10.1371/journal.pone.0082065
859:melanin biosynthetic process
828:smooth endoplasmic reticulum
637:microfilament motor activity
5101:Plakoglobin (gamma catenin)
2554:The Journal of Neuroscience
2323:The Journal of Cell Biology
1936:The Journal of Neuroscience
748:photoreceptor outer segment
647:cytoskeletal motor activity
5403:
969:vesicle-mediated transport
959:melanocyte differentiation
939:developmental pigmentation
524:lateral geniculate nucleus
5357:
2959:
2634:Journal of Neurochemistry
1586:"Mouse PubMed Reference:"
1568:"Human PubMed Reference:"
1366:
1361:
1357:
1350:
1334:
1315:
1300:
1263:
1252:
1237:
1200:
1189:
1176:
1172:
1157:
1153:
1144:
1131:
1127:
1112:
1108:
1099:
1086:
1082:
1067:
1063:
1054:
1039:
1032:
1028:
1012:
904:melanin metabolic process
667:identical protein binding
607:
603:
586:
577:
568:
555:
508:medial geniculate nucleus
504:
495:
442:
433:
403:
395:
391:
374:
361:
324:
303:
294:
290:
273:
260:
223:
200:
191:
187:
142:
139:
129:
122:
117:
82:
77:
60:
55:
50:
46:
37:
32:
5327:Prokaryotic cytoskeleton
2379:10.1074/jbc.274.28.19771
1410:MYO5A has been shown to
1380:Unconventional myosin-Va
1321:Chr 15: 52.31 – 52.53 Mb
989:hair follicle maturation
536:dorsal tegmental nucleus
2704:Journal of Cell Science
2100:10.1126/science.1062257
1895:10.1073/pnas.91.14.6549
1701:10.1074/jbc.M110.187286
1490:(AF) are being studied.
1471:and the progression of
1328:Chr 9: 74.98 – 75.13 Mb
879:melanosome localization
2784:10.1091/mbc.01-12-0595
2750:10.1074/jbc.M202574200
2682:10.1074/jbc.C200005200
2612:10.1074/jbc.M010320200
2498:10.1006/geno.1999.6081
2335:10.1083/jcb.143.6.1535
2302:10.1006/bbrc.1998.9644
1997:10.1091/mbc.01-12-0595
1846:10.1006/geno.1994.1088
1443:type 1, also known as
677:actin filament binding
520:ventral tegmental area
478:superior frontal gyrus
5387:Genes mutated in mice
3947:(hard alpha-keratins)
3778:(soft alpha-keratins)
2716:10.1242/jcs.115.5.991
1466:(SVs) trafficking of
1434:Clinical significance
838:glutamatergic synapse
813:extracellular exosome
808:intermediate filament
783:endoplasmic reticulum
528:stroma of bone marrow
516:medial dorsal nucleus
217:Chromosome 15 (human)
5362:cytoskeletal defects
5322:Major sperm proteins
1751:Circulation Research
919:melanosome transport
864:synapse organization
763:microtubule plus-end
319:Chromosome 9 (mouse)
78:List of PDB id codes
51:Available structures
3775:Epithelial keratins
2870:2002FEBSL.517..233N
2409:1999Natur.400..590M
2189:www.clinicalkey.com
2148:2017NatSR...743692A
2092:2001Sci...293.1829P
2046:2002FEBSL.517..233N
1886:1994PNAS...91.6549B
1694:(16): 14352–14361.
1626:2013PLoSO...882065V
1488:atrial fibrillation
622:calcium ion binding
358:9 D|9 42.26 cM
2710:(Pt 5): 991–1004.
2446:Journal of Anatomy
2261:10.1038/ng0797-289
2136:Scientific Reports
1441:Griscelli syndrome
1134:ENSMUSG00000034593
847:Biological process
773:neuronal cell body
698:recycling endosome
686:Cellular component
632:calmodulin binding
627:nucleotide binding
615:Molecular function
5369:
5368:
5310:
5309:
5070:
5069:
4315:
4314:
4197:
4196:
3740:
3739:
3683:
3682:
3042:
3041:
2231:10.1159/000133937
2156:10.1038/srep43692
2086:(5536): 1829–32.
1473:neurodegeneration
1468:neurotransmitters
1464:synaptic vesicles
1445:Elejalde syndrome
1377:
1376:
1373:
1372:
1346:
1345:
1311:
1310:
1290:
1289:
1248:
1247:
1227:
1226:
1185:
1184:
1166:
1165:
1140:
1139:
1121:
1120:
1095:
1094:
1076:
1075:
1024:
1023:
974:visual perception
934:protein transport
869:insulin secretion
793:neuron projection
758:secretory granule
599:
598:
595:
594:
564:
563:
551:
550:
489:
488:
482:entorhinal cortex
470:postcentral gyrus
387:
386:
286:
285:
181:MYO5A - orthologs
113:
112:
109:
108:
61:Ortholog search:
16:(Redirected from
5394:
4331:
3771:
3753:
3114:
3105:
3091:
3069:
3062:
3055:
3046:
3028:
3013:
2998:
2983:
2968:
2948:
2941:
2934:
2925:
2891:
2881:
2848:
2838:
2805:
2795:
2762:
2752:
2743:(28): 25423–30.
2727:
2694:
2684:
2659:
2649:
2624:
2614:
2605:(17): 14059–66.
2589:
2579:
2569:
2544:
2534:
2509:
2479:
2469:
2436:
2391:
2381:
2356:
2346:
2313:
2280:
2242:
2199:
2198:
2196:
2195:
2181:
2170:
2169:
2167:
2126:
2120:
2119:
2074:
2068:
2067:
2057:
2025:
2019:
2018:
2008:
1976:
1970:
1969:
1959:
1927:
1918:
1917:
1907:
1897:
1865:
1859:
1858:
1848:
1824:
1818:
1817:
1815:
1813:
1799:
1793:
1792:
1782:
1741:
1732:
1731:
1721:
1703:
1679:
1666:
1665:
1655:
1637:
1605:
1594:
1593:
1582:
1576:
1575:
1564:
1558:
1548:
1537:
1527:
1426:, RPGRIP1L, and
1359:
1358:
1330:
1323:
1306:
1294:
1285:
1257:
1253:RefSeq (protein)
1243:
1231:
1222:
1194:
1170:
1151:
1125:
1106:
1080:
1061:
1030:
605:
591:
582:
575:
560:
500:
498:Top expressed in
493:
458:Brodmann area 23
450:endothelial cell
438:
436:Top expressed in
431:
410:
393:
383:
370:
359:
344:
337:
331:
320:
308:
292:
282:
269:
258:
243:
236:
230:
219:
205:
189:
183:
134:
127:
104:
75:
69:
48:
47:
42:
30:
21:
5402:
5401:
5397:
5396:
5395:
5393:
5392:
5391:
5372:
5371:
5370:
5365:
5353:
5306:
5209:
5115:
5066:
4979:
4958:
4910:
4733:
4525:
4477:
4323:
4311:
4281:
4228:
4193:
4177:
4061:Ungrouped alpha
4056:
3946:
3938:
3777:
3763:
3757:
3747:
3736:
3679:
3476:
3155:
3097:
3082:
3073:
3043:
3038:
3035:
3029:
3020:
3014:
3005:
2999:
2990:
2984:
2975:
2969:
2955:
2952:
2899:
2894:
2851:
2808:
2765:
2730:
2697:
2675:(14): 12432–6.
2662:
2627:
2592:
2560:(12): 4524–34.
2547:
2512:
2482:
2439:
2403:(6744): 590–3.
2394:
2372:(28): 19771–7.
2359:
2316:
2283:
2249:Nature Genetics
2245:
2212:
2208:
2206:Further reading
2203:
2202:
2193:
2191:
2183:
2182:
2173:
2128:
2127:
2123:
2076:
2075:
2071:
2027:
2026:
2022:
1978:
1977:
1973:
1942:(12): 4524–34.
1929:
1928:
1921:
1880:(14): 6549–53.
1867:
1866:
1862:
1826:
1825:
1821:
1811:
1809:
1807:www.uniprot.org
1801:
1800:
1796:
1743:
1742:
1735:
1681:
1680:
1669:
1607:
1606:
1597:
1584:
1583:
1579:
1566:
1565:
1561:
1549:
1540:
1528:
1519:
1514:
1497:
1436:
1408:
1399:
1368:View/Edit Mouse
1363:View/Edit Human
1326:
1319:
1316:Location (UCSC)
1302:
1281:
1277:
1273:
1269:
1265:
1239:
1218:
1214:
1210:
1206:
1202:
1115:ENSG00000197535
1008:
842:
718:Golgi apparatus
681:
672:protein binding
587:
556:
547:
544:globus pallidus
542:
538:
534:
530:
526:
522:
518:
514:
510:
496:
485:
480:
476:
472:
468:
464:
462:pars reticulata
460:
456:
452:
448:
434:
378:
365:
357:
347:
346:
345:
338:
318:
295:Gene location (
277:
264:
256:
246:
245:
244:
237:
215:
192:Gene location (
143:
130:
123:
84:
62:
28:
23:
22:
15:
12:
11:
5:
5400:
5398:
5390:
5389:
5384:
5374:
5373:
5367:
5366:
5358:
5355:
5354:
5352:
5351:
5350:
5349:
5344:
5339:
5334:
5324:
5318:
5316:
5312:
5311:
5308:
5307:
5305:
5304:
5299:
5294:
5293:
5292:
5287:
5277:
5272:
5271:
5270:
5260:
5259:
5258:
5253:
5248:
5243:
5238:
5233:
5228:
5226:Corneodesmosin
5217:
5215:
5211:
5210:
5208:
5207:
5206:
5205:
5200:
5195:
5190:
5185:
5180:
5175:
5165:
5164:
5163:
5158:
5153:
5143:
5138:
5137:
5136:
5125:
5123:
5117:
5116:
5114:
5113:
5108:
5103:
5098:
5097:
5096:
5086:
5080:
5078:
5072:
5071:
5068:
5067:
5065:
5064:
5063:
5062:
5057:
5052:
5042:
5041:
5040:
5035:
5030:
5025:
5020:
5010:
5005:
5004:
5003:
4993:
4987:
4985:
4981:
4980:
4978:
4977:
4972:
4966:
4964:
4960:
4959:
4957:
4956:
4951:
4946:
4941:
4936:
4931:
4926:
4920:
4918:
4912:
4911:
4909:
4908:
4903:
4898:
4893:
4888:
4883:
4878:
4873:
4868:
4863:
4858:
4853:
4848:
4841:
4840:
4835:
4830:
4825:
4820:
4815:
4810:
4805:
4800:
4795:
4790:
4785:
4780:
4775:
4770:
4765:
4760:
4755:
4750:
4743:
4741:
4735:
4734:
4732:
4731:
4726:
4721:
4716:
4711:
4706:
4701:
4696:
4691:
4686:
4681:
4676:
4671:
4666:
4661:
4656:
4651:
4646:
4641:
4636:
4631:
4626:
4621:
4616:
4611:
4606:
4601:
4596:
4591:
4586:
4581:
4576:
4571:
4566:
4561:
4556:
4551:
4546:
4541:
4535:
4533:
4527:
4526:
4524:
4523:
4518:
4513:
4508:
4503:
4498:
4493:
4487:
4485:
4479:
4478:
4476:
4475:
4470:
4465:
4460:
4455:
4450:
4445:
4440:
4435:
4430:
4425:
4420:
4415:
4410:
4405:
4400:
4395:
4390:
4385:
4380:
4375:
4370:
4365:
4360:
4355:
4350:
4345:
4339:
4337:
4328:
4317:
4316:
4313:
4312:
4310:
4309:
4304:
4299:
4293:Nuclear lamins
4289:
4287:
4283:
4282:
4280:
4279:
4274:
4269:
4268:
4267:
4262:
4257:
4247:
4242:
4236:
4234:
4230:
4229:
4227:
4226:
4221:
4216:
4211:
4205:
4203:
4199:
4198:
4195:
4194:
4192:
4191:
4185:
4183:
4179:
4178:
4176:
4175:
4174:
4173:
4168:
4163:
4158:
4153:
4148:
4143:
4138:
4133:
4128:
4115:
4114:
4113:
4112:
4107:
4102:
4097:
4092:
4087:
4082:
4077:
4064:
4062:
4058:
4057:
4055:
4054:
4053:
4052:
4047:
4042:
4037:
4032:
4027:
4010:
4009:
4008:
4007:
4002:
3997:
3992:
3987:
3982:
3977:
3972:
3967:
3950:
3948:
3940:
3939:
3937:
3936:
3935:
3934:
3929:
3924:
3919:
3914:
3909:
3904:
3899:
3894:
3889:
3872:
3871:
3870:
3869:
3859:
3858:
3857:
3845:
3844:
3843:
3838:
3833:
3828:
3823:
3818:
3813:
3808:
3803:
3798:
3781:
3779:
3768:
3750:
3742:
3741:
3738:
3737:
3735:
3734:
3729:
3724:
3723:
3722:
3717:
3712:
3702:
3697:
3691:
3689:
3685:
3684:
3681:
3680:
3678:
3677:
3672:
3671:
3670:
3665:
3655:
3650:
3649:
3648:
3643:
3642:
3641:
3636:
3619:
3617:Arp2/3 complex
3614:
3613:
3612:
3607:
3602:
3597:
3586:
3585:
3584:
3583:
3578:
3573:
3568:
3558:
3557:
3556:
3542:
3531:
3512:
3511:
3510:
3505:
3500:
3495:
3484:
3482:
3478:
3477:
3475:
3474:
3473:
3472:
3467:
3462:
3457:
3452:
3447:
3442:
3437:
3432:
3427:
3422:
3417:
3412:
3402:
3401:
3400:
3395:
3387:
3386:
3385:
3377:
3376:
3375:
3367:
3366:
3365:
3360:
3352:
3351:
3350:
3345:
3337:
3336:
3335:
3327:
3326:
3325:
3320:
3315:
3307:
3306:
3305:
3300:
3292:
3291:
3290:
3285:
3280:
3275:
3270:
3265:
3260:
3255:
3250:
3245:
3240:
3235:
3230:
3225:
3220:
3212:
3211:
3210:
3204:
3199:
3194:
3189:
3184:
3179:
3174:
3165:
3163:
3157:
3156:
3154:
3153:
3148:
3143:
3138:
3133:
3128:
3122:
3120:
3111:
3102:
3095:Microfilaments
3088:
3084:
3083:
3074:
3072:
3071:
3064:
3057:
3049:
3040:
3039:
3037:
3036:
3030:
3023:
3021:
3015:
3008:
3006:
3000:
2993:
2991:
2985:
2978:
2976:
2970:
2963:
2960:
2957:
2956:
2953:
2951:
2950:
2943:
2936:
2928:
2922:
2921:
2898:
2897:External links
2895:
2893:
2892:
2864:(1–3): 233–8.
2849:
2827:10.1086/341606
2806:
2778:(5): 1735–49.
2763:
2728:
2695:
2660:
2625:
2590:
2545:
2510:
2492:(3): 299–306.
2480:
2437:
2392:
2357:
2329:(6): 1535–45.
2314:
2281:
2243:
2209:
2207:
2204:
2201:
2200:
2171:
2121:
2069:
2040:(1–3): 233–8.
2020:
1991:(5): 1735–49.
1971:
1919:
1860:
1819:
1794:
1757:(6): 982–992.
1733:
1667:
1620:(12): e82065.
1595:
1577:
1559:
1538:
1516:
1515:
1513:
1510:
1509:
1508:
1503:
1496:
1493:
1492:
1491:
1476:
1460:neurofilaments
1456:
1435:
1432:
1407:
1404:
1398:
1395:
1375:
1374:
1371:
1370:
1365:
1355:
1354:
1348:
1347:
1344:
1343:
1341:
1339:
1332:
1331:
1324:
1317:
1313:
1312:
1309:
1308:
1298:
1297:
1291:
1288:
1287:
1261:
1260:
1254:
1250:
1249:
1246:
1245:
1235:
1234:
1228:
1225:
1224:
1198:
1197:
1191:
1187:
1186:
1183:
1182:
1174:
1173:
1167:
1164:
1163:
1155:
1154:
1148:
1142:
1141:
1138:
1137:
1129:
1128:
1122:
1119:
1118:
1110:
1109:
1103:
1097:
1096:
1093:
1092:
1084:
1083:
1077:
1074:
1073:
1065:
1064:
1058:
1052:
1051:
1046:
1041:
1037:
1036:
1026:
1025:
1022:
1021:
1010:
1009:
1007:
1006:
1001:
996:
991:
986:
981:
976:
971:
966:
961:
956:
951:
946:
941:
936:
931:
926:
921:
916:
911:
906:
901:
896:
891:
886:
881:
876:
871:
866:
861:
856:
850:
848:
844:
843:
841:
840:
835:
830:
825:
820:
818:myosin complex
815:
810:
805:
800:
795:
790:
788:actin filament
785:
780:
778:early endosome
775:
770:
768:filopodium tip
765:
760:
755:
750:
745:
740:
735:
730:
725:
720:
715:
710:
705:
700:
695:
689:
687:
683:
682:
680:
679:
674:
669:
664:
659:
654:
649:
644:
639:
634:
629:
624:
618:
616:
612:
611:
601:
600:
597:
596:
593:
592:
584:
583:
572:
566:
565:
562:
561:
553:
552:
549:
548:
546:
545:
541:
537:
533:
529:
525:
521:
517:
513:
512:pontine nuclei
509:
505:
502:
501:
490:
487:
486:
484:
483:
479:
475:
471:
467:
463:
459:
455:
451:
447:
443:
440:
439:
427:
426:
418:
407:
401:
400:
397:RNA expression
389:
388:
385:
384:
376:
372:
371:
363:
360:
355:
349:
348:
339:
332:
326:
322:
321:
316:
310:
309:
301:
300:
288:
287:
284:
283:
275:
271:
270:
262:
259:
254:
248:
247:
238:
231:
225:
221:
220:
213:
207:
206:
198:
197:
185:
184:
141:
137:
136:
128:
120:
119:
115:
114:
111:
110:
107:
106:
80:
79:
71:
70:
59:
53:
52:
44:
43:
35:
34:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
5399:
5388:
5385:
5383:
5380:
5379:
5377:
5364:
5363:
5356:
5348:
5345:
5343:
5340:
5338:
5335:
5333:
5330:
5329:
5328:
5325:
5323:
5320:
5319:
5317:
5313:
5303:
5300:
5298:
5295:
5291:
5288:
5286:
5283:
5282:
5281:
5278:
5276:
5273:
5269:
5266:
5265:
5264:
5261:
5257:
5254:
5252:
5249:
5247:
5244:
5242:
5239:
5237:
5234:
5232:
5229:
5227:
5224:
5223:
5222:
5219:
5218:
5216:
5212:
5204:
5201:
5199:
5196:
5194:
5191:
5189:
5186:
5184:
5181:
5179:
5176:
5174:
5171:
5170:
5169:
5166:
5162:
5159:
5157:
5154:
5152:
5149:
5148:
5147:
5144:
5142:
5139:
5135:
5132:
5131:
5130:
5127:
5126:
5124:
5122:
5118:
5112:
5109:
5107:
5106:Delta catenin
5104:
5102:
5099:
5095:
5092:
5091:
5090:
5087:
5085:
5084:Alpha catenin
5082:
5081:
5079:
5077:
5073:
5061:
5058:
5056:
5053:
5051:
5048:
5047:
5046:
5043:
5039:
5036:
5034:
5031:
5029:
5026:
5024:
5021:
5019:
5016:
5015:
5014:
5011:
5009:
5006:
5002:
4999:
4998:
4997:
4994:
4992:
4989:
4988:
4986:
4982:
4976:
4973:
4971:
4968:
4967:
4965:
4961:
4955:
4952:
4950:
4947:
4945:
4942:
4940:
4937:
4935:
4932:
4930:
4927:
4925:
4922:
4921:
4919:
4917:
4913:
4907:
4904:
4902:
4899:
4897:
4894:
4892:
4889:
4887:
4884:
4882:
4879:
4877:
4874:
4872:
4869:
4867:
4864:
4862:
4859:
4857:
4854:
4852:
4849:
4847:
4844:cytoplasmic:
4843:
4842:
4839:
4836:
4834:
4831:
4829:
4826:
4824:
4821:
4819:
4816:
4814:
4811:
4809:
4806:
4804:
4801:
4799:
4796:
4794:
4791:
4789:
4786:
4784:
4781:
4779:
4776:
4774:
4771:
4769:
4766:
4764:
4761:
4759:
4756:
4754:
4751:
4749:
4745:
4744:
4742:
4740:
4736:
4730:
4727:
4725:
4722:
4720:
4717:
4715:
4712:
4710:
4707:
4705:
4702:
4700:
4697:
4695:
4692:
4690:
4687:
4685:
4682:
4680:
4677:
4675:
4672:
4670:
4667:
4665:
4662:
4660:
4657:
4655:
4652:
4650:
4647:
4645:
4642:
4640:
4637:
4635:
4632:
4630:
4627:
4625:
4622:
4620:
4617:
4615:
4612:
4610:
4607:
4605:
4602:
4600:
4597:
4595:
4592:
4590:
4587:
4585:
4582:
4580:
4577:
4575:
4572:
4570:
4567:
4565:
4562:
4560:
4557:
4555:
4552:
4550:
4547:
4545:
4542:
4540:
4537:
4536:
4534:
4532:
4528:
4522:
4519:
4517:
4514:
4512:
4509:
4507:
4504:
4502:
4499:
4497:
4494:
4492:
4489:
4488:
4486:
4484:
4480:
4474:
4471:
4469:
4466:
4464:
4461:
4459:
4456:
4454:
4451:
4449:
4446:
4444:
4441:
4439:
4436:
4434:
4431:
4429:
4426:
4424:
4421:
4419:
4416:
4414:
4411:
4409:
4406:
4404:
4401:
4399:
4396:
4394:
4391:
4389:
4386:
4384:
4381:
4379:
4376:
4374:
4371:
4369:
4366:
4364:
4361:
4359:
4356:
4354:
4351:
4349:
4346:
4344:
4341:
4340:
4338:
4336:
4332:
4329:
4327:
4322:
4318:
4308:
4305:
4303:
4300:
4298:
4294:
4291:
4290:
4288:
4284:
4278:
4275:
4273:
4270:
4266:
4263:
4261:
4258:
4256:
4253:
4252:
4251:
4250:Neurofilament
4248:
4246:
4243:
4241:
4238:
4237:
4235:
4231:
4225:
4222:
4220:
4217:
4215:
4212:
4210:
4207:
4206:
4204:
4200:
4190:
4187:
4186:
4184:
4180:
4172:
4169:
4167:
4164:
4162:
4159:
4157:
4154:
4152:
4149:
4147:
4144:
4142:
4139:
4137:
4134:
4132:
4129:
4127:
4124:
4123:
4122:
4121:
4120:chromosome 12
4117:
4116:
4111:
4108:
4106:
4103:
4101:
4098:
4096:
4093:
4091:
4088:
4086:
4083:
4081:
4078:
4076:
4073:
4072:
4071:
4070:
4069:chromosome 17
4066:
4065:
4063:
4059:
4051:
4048:
4046:
4043:
4041:
4038:
4036:
4033:
4031:
4028:
4026:
4023:
4022:
4021:
4020:
4019:chromosome 12
4016:
4012:
4011:
4006:
4003:
4001:
3998:
3996:
3993:
3991:
3988:
3986:
3983:
3981:
3978:
3976:
3973:
3971:
3968:
3966:
3963:
3962:
3961:
3960:
3959:chromosome 17
3956:
3952:
3951:
3949:
3945:
3944:Hair keratins
3941:
3933:
3930:
3928:
3925:
3923:
3920:
3918:
3915:
3913:
3910:
3908:
3905:
3903:
3900:
3898:
3895:
3893:
3890:
3888:
3885:
3884:
3883:
3882:
3881:chromosome 12
3878:
3874:
3873:
3868:
3865:
3864:
3863:
3860:
3856:
3853:
3852:
3851:
3850:
3849:chromosome 12
3846:
3842:
3839:
3837:
3834:
3832:
3829:
3827:
3824:
3822:
3819:
3817:
3814:
3812:
3809:
3807:
3804:
3802:
3799:
3797:
3794:
3793:
3792:
3791:
3790:chromosome 17
3787:
3783:
3782:
3780:
3776:
3772:
3769:
3766:
3761:
3754:
3751:
3749:
3746:Intermediate
3743:
3733:
3730:
3728:
3725:
3721:
3718:
3716:
3713:
3711:
3708:
3707:
3706:
3703:
3701:
3698:
3696:
3693:
3692:
3690:
3686:
3676:
3673:
3669:
3666:
3664:
3661:
3660:
3659:
3656:
3654:
3651:
3647:
3644:
3640:
3637:
3635:
3632:
3631:
3630:
3627:
3626:
3625:
3624:
3620:
3618:
3615:
3611:
3608:
3606:
3603:
3601:
3598:
3596:
3593:
3592:
3591:
3588:
3587:
3582:
3579:
3577:
3574:
3572:
3569:
3567:
3564:
3563:
3562:
3559:
3555:
3552:
3549:
3546:
3543:
3541:
3538:
3535:
3532:
3530:
3527:
3524:
3521:
3518:
3517:
3516:
3513:
3509:
3506:
3504:
3501:
3499:
3496:
3494:
3491:
3490:
3489:
3486:
3485:
3483:
3479:
3471:
3468:
3466:
3463:
3461:
3458:
3456:
3453:
3451:
3448:
3446:
3443:
3441:
3438:
3436:
3433:
3431:
3428:
3426:
3423:
3421:
3418:
3416:
3413:
3411:
3408:
3407:
3406:
3403:
3399:
3396:
3394:
3391:
3390:
3388:
3384:
3381:
3380:
3378:
3374:
3371:
3370:
3368:
3364:
3361:
3359:
3356:
3355:
3353:
3349:
3346:
3344:
3341:
3340:
3338:
3334:
3331:
3330:
3328:
3324:
3321:
3319:
3316:
3314:
3311:
3310:
3308:
3304:
3301:
3299:
3296:
3295:
3293:
3289:
3286:
3284:
3281:
3279:
3276:
3274:
3271:
3269:
3266:
3264:
3261:
3259:
3256:
3254:
3251:
3249:
3246:
3244:
3241:
3239:
3236:
3234:
3231:
3229:
3226:
3224:
3221:
3219:
3216:
3215:
3213:
3208:
3205:
3203:
3200:
3198:
3195:
3193:
3190:
3188:
3185:
3183:
3180:
3178:
3175:
3173:
3170:
3169:
3167:
3166:
3164:
3162:
3158:
3152:
3149:
3147:
3144:
3142:
3139:
3137:
3134:
3132:
3129:
3127:
3124:
3123:
3121:
3119:
3115:
3112:
3110:
3106:
3103:
3101:
3096:
3092:
3089:
3085:
3081:
3077:
3070:
3065:
3063:
3058:
3056:
3051:
3050:
3047:
3033:
3027:
3022:
3018:
3012:
3007:
3003:
2997:
2992:
2988:
2982:
2977:
2973:
2967:
2962:
2958:
2949:
2944:
2942:
2937:
2935:
2930:
2929:
2926:
2919:
2915:
2914:
2909:
2905:
2901:
2900:
2896:
2889:
2885:
2880:
2875:
2871:
2867:
2863:
2859:
2855:
2850:
2846:
2842:
2837:
2832:
2828:
2824:
2821:(2): 407–14.
2820:
2816:
2812:
2807:
2803:
2799:
2794:
2789:
2785:
2781:
2777:
2773:
2769:
2764:
2760:
2756:
2751:
2746:
2742:
2738:
2734:
2729:
2725:
2721:
2717:
2713:
2709:
2705:
2701:
2696:
2692:
2688:
2683:
2678:
2674:
2670:
2666:
2661:
2657:
2653:
2648:
2643:
2639:
2635:
2631:
2626:
2622:
2618:
2613:
2608:
2604:
2600:
2596:
2591:
2587:
2583:
2578:
2573:
2568:
2563:
2559:
2555:
2551:
2546:
2542:
2538:
2533:
2528:
2524:
2520:
2516:
2511:
2507:
2503:
2499:
2495:
2491:
2487:
2481:
2477:
2473:
2468:
2463:
2459:
2455:
2452:(2): 173–84.
2451:
2447:
2443:
2438:
2434:
2430:
2426:
2422:
2418:
2417:10.1038/23072
2414:
2410:
2406:
2402:
2398:
2393:
2389:
2385:
2380:
2375:
2371:
2367:
2363:
2358:
2354:
2350:
2345:
2340:
2336:
2332:
2328:
2324:
2320:
2315:
2311:
2307:
2303:
2299:
2296:(2): 329–33.
2295:
2291:
2287:
2282:
2278:
2274:
2270:
2266:
2262:
2258:
2255:(3): 289–92.
2254:
2250:
2244:
2240:
2236:
2232:
2228:
2225:(1–2): 53–8.
2224:
2220:
2216:
2211:
2210:
2205:
2190:
2186:
2185:"ClinicalKey"
2180:
2178:
2176:
2172:
2166:
2161:
2157:
2153:
2149:
2145:
2141:
2137:
2133:
2125:
2122:
2117:
2113:
2109:
2105:
2101:
2097:
2093:
2089:
2085:
2081:
2073:
2070:
2065:
2061:
2056:
2051:
2047:
2043:
2039:
2035:
2031:
2024:
2021:
2016:
2012:
2007:
2002:
1998:
1994:
1990:
1986:
1982:
1975:
1972:
1967:
1963:
1958:
1953:
1949:
1945:
1941:
1937:
1933:
1926:
1924:
1920:
1915:
1911:
1906:
1901:
1896:
1891:
1887:
1883:
1879:
1875:
1871:
1864:
1861:
1856:
1852:
1847:
1842:
1839:(3): 407–16.
1838:
1834:
1830:
1823:
1820:
1808:
1804:
1798:
1795:
1790:
1786:
1781:
1776:
1772:
1768:
1764:
1760:
1756:
1752:
1748:
1740:
1738:
1734:
1729:
1725:
1720:
1715:
1711:
1707:
1702:
1697:
1693:
1689:
1685:
1678:
1676:
1674:
1672:
1668:
1663:
1659:
1654:
1649:
1645:
1641:
1636:
1631:
1627:
1623:
1619:
1615:
1611:
1604:
1602:
1600:
1596:
1591:
1587:
1581:
1578:
1573:
1569:
1563:
1560:
1556:
1552:
1547:
1545:
1543:
1539:
1535:
1531:
1526:
1524:
1522:
1518:
1511:
1507:
1504:
1502:
1499:
1498:
1494:
1489:
1485:
1481:
1477:
1474:
1469:
1465:
1461:
1457:
1454:
1450:
1446:
1442:
1438:
1437:
1433:
1431:
1429:
1425:
1421:
1417:
1413:
1405:
1403:
1396:
1394:
1392:
1389:
1385:
1384:motor protein
1381:
1369:
1364:
1360:
1356:
1353:
1349:
1342:
1340:
1337:
1333:
1329:
1325:
1322:
1318:
1314:
1307:
1305:
1299:
1295:
1292:
1286:
1284:
1280:
1276:
1272:
1268:
1262:
1258:
1255:
1251:
1244:
1242:
1236:
1232:
1229:
1223:
1221:
1217:
1213:
1209:
1205:
1199:
1195:
1192:
1190:RefSeq (mRNA)
1188:
1181:
1180:
1175:
1171:
1168:
1162:
1161:
1156:
1152:
1149:
1147:
1143:
1136:
1135:
1130:
1126:
1123:
1117:
1116:
1111:
1107:
1104:
1102:
1098:
1091:
1090:
1085:
1081:
1078:
1072:
1071:
1066:
1062:
1059:
1057:
1053:
1050:
1047:
1045:
1042:
1038:
1035:
1031:
1027:
1020:
1016:
1011:
1005:
1002:
1000:
997:
995:
992:
990:
987:
985:
982:
980:
977:
975:
972:
970:
967:
965:
962:
960:
957:
955:
952:
950:
947:
945:
942:
940:
937:
935:
932:
930:
927:
925:
922:
920:
917:
915:
912:
910:
907:
905:
902:
900:
897:
895:
894:odontogenesis
892:
890:
887:
885:
882:
880:
877:
875:
872:
870:
867:
865:
862:
860:
857:
855:
852:
851:
849:
846:
845:
839:
836:
834:
831:
829:
826:
824:
821:
819:
816:
814:
811:
809:
806:
804:
801:
799:
796:
794:
791:
789:
786:
784:
781:
779:
776:
774:
771:
769:
766:
764:
761:
759:
756:
754:
751:
749:
746:
744:
741:
739:
736:
734:
731:
729:
726:
724:
721:
719:
716:
714:
713:late endosome
711:
709:
706:
704:
701:
699:
696:
694:
691:
690:
688:
685:
684:
678:
675:
673:
670:
668:
665:
663:
660:
658:
655:
653:
650:
648:
645:
643:
642:actin binding
640:
638:
635:
633:
630:
628:
625:
623:
620:
619:
617:
614:
613:
610:
609:Gene ontology
606:
602:
590:
585:
581:
576:
573:
571:
567:
559:
554:
543:
539:
535:
531:
527:
523:
519:
515:
511:
507:
506:
503:
499:
494:
491:
481:
477:
473:
469:
466:parietal lobe
465:
461:
457:
454:Pars compacta
453:
449:
445:
444:
441:
437:
432:
429:
428:
425:
423:
419:
417:
416:
412:
411:
408:
406:
402:
398:
394:
390:
382:
377:
373:
369:
364:
354:
350:
343:
336:
330:
323:
315:
311:
307:
302:
298:
293:
289:
281:
276:
272:
268:
263:
253:
249:
242:
235:
229:
222:
218:
212:
208:
204:
199:
195:
190:
186:
182:
178:
174:
170:
166:
162:
158:
154:
150:
146:
138:
133:
126:
121:
116:
105:
103:
99:
95:
91:
87:
81:
76:
73:
72:
68:
65:
58:
54:
49:
45:
41:
36:
31:
19:
5359:
5134:Dystroglycan
5089:Beta catenin
4321:Microtubules
4189:Beta-keratin
4118:
4067:
4013:
3953:
3875:
3861:
3847:
3784:
3621:
3488:Tropomodulin
3080:cytoskeleton
3031:
3016:
3001:
2986:
2971:
2911:
2861:
2858:FEBS Letters
2857:
2818:
2814:
2775:
2771:
2740:
2736:
2707:
2703:
2672:
2668:
2640:(1): 75–87.
2637:
2633:
2602:
2598:
2557:
2553:
2525:(4): 731–3.
2522:
2518:
2489:
2485:
2449:
2445:
2400:
2396:
2369:
2365:
2326:
2322:
2293:
2289:
2252:
2248:
2222:
2218:
2192:. Retrieved
2188:
2139:
2135:
2124:
2083:
2079:
2072:
2037:
2034:FEBS Letters
2033:
2023:
1988:
1984:
1974:
1939:
1935:
1877:
1873:
1863:
1836:
1832:
1822:
1810:. Retrieved
1806:
1797:
1754:
1750:
1691:
1687:
1617:
1613:
1589:
1580:
1571:
1562:
1409:
1406:Interactions
1400:
1387:
1379:
1378:
1301:
1283:NP_001369278
1279:NP_001369277
1275:NP_001369276
1271:NP_001135967
1264:
1238:
1220:NM_001382349
1216:NM_001382348
1212:NM_001382347
1208:NM_001142495
1201:
1177:
1158:
1132:
1113:
1087:
1068:
1048:
1043:
949:pigmentation
420:
413:
140:External IDs
83:
5280:Plakophilin
5231:Desmoplakin
4991:Tau protein
3765:Cytokeratin
3561:Tropomyosin
3109:Myofilament
2954:PDB gallery
944:myelination
833:postsynapse
728:growth cone
657:RNA binding
652:ATP binding
379:75,130,970
366:74,978,297
278:52,529,132
265:52,307,281
118:Identifiers
5376:Categories
5360:See also:
5332:Crescentin
5251:Periplakin
5241:Envoplakin
5129:Dystrophin
4746:axonemal:
4240:Internexin
4219:Peripherin
2194:2019-12-04
1557:, May 2017
1536:, May 2017
1512:References
1478:MYO5A and
1449:melanosome
979:exocytosis
803:actomyosin
753:peroxisome
738:melanosome
424:(ortholog)
161:HomoloGene
4949:Centrin 3
4944:Centrin 2
4939:Centrin 1
4277:Syncoilin
4182:Not alpha
3748:filaments
3700:Fibrillin
2433:204995058
2142:: 43692.
1771:0009-7330
1710:0021-9258
1644:1932-6203
1453:hypotonia
1397:Structure
1304:NP_034994
1267:NP_000250
1241:NM_010864
1204:NM_000259
1034:Orthologs
994:transport
693:cytoplasm
532:subiculum
169:GeneCards
5315:Nonhuman
5275:Vinculin
5236:Dystonin
5168:Spectrin
5141:Utrophin
5121:Membrane
5076:Catenins
5008:Stathmin
4996:Dynactin
4876:DYNC2LI1
4871:DYNC1LI2
4866:DYNC1LI1
4531:Kinesins
4335:Tubulins
4224:Vimentin
3756:Type 1/2
3658:Profilin
3653:Gelsolin
3515:Troponin
3076:Proteins
2888:12062444
2845:12058346
2802:12006666
2759:11980908
2724:11870218
2691:11856727
2656:11432975
2621:11148209
2586:10844022
2541:10733681
2506:10704277
2486:Genomics
2476:10529054
2425:10448864
2388:10391919
2277:21815627
2108:11546872
2064:12062444
2015:12006666
1966:10844022
1833:Genomics
1812:11 April
1789:24508725
1728:21349835
1662:24339992
1614:PLOS ONE
1553:–
1532:–
1495:See also
1412:interact
1352:Wikidata
1013:Sources:
798:lysosome
723:membrane
540:habenula
5302:PLEKHA7
5256:Plectin
5221:Plakins
5146:Ankyrin
5045:Dynamin
4975:Spastin
4970:Katanin
4934:CAMSAP3
4929:CAMSAP2
4924:CAMSAP1
4896:DYNLRB2
4891:DYNLRB1
4861:DYNC1I2
4856:DYNC1I1
4851:DYNC2H1
4846:DYNC1H1
4739:Dyneins
4463:TUBGCP6
4458:TUBGCP5
4453:TUBGCP4
4448:TUBGCP3
4443:TUBGCP2
4272:Synemin
4015:type II
3877:type II
3760:Keratin
3705:Filamin
3646:Destrin
3629:Cofilin
3590:Actinin
3161:Myosins
3078:of the
2918:PDBe-KB
2908:UniProt
2866:Bibcode
2577:6772433
2467:1467982
2405:Bibcode
2353:9852149
2344:2132970
2310:9826529
2269:9207796
2239:7835087
2165:5339802
2144:Bibcode
2116:5638023
2088:Bibcode
2080:Science
2042:Bibcode
1957:6772433
1914:8022818
1882:Bibcode
1855:8188282
1780:4213814
1719:3077635
1653:3858360
1622:Bibcode
1555:Ensembl
1534:Ensembl
1146:UniProt
1101:Ensembl
1040:Species
1019:QuickGO
708:cytosol
703:vesicle
399:pattern
257:15q21.2
125:Aliases
5203:SPTBN5
5198:SPTBN4
5193:SPTBN2
5188:SPTBN1
5178:SPTAN1
5013:Tektin
4906:DYNLT3
4901:DYNLT1
4886:DYNLL2
4881:DYNLL1
4828:DNALI1
4813:DNAH17
4808:DNAH14
4803:DNAH13
4798:DNAH12
4793:DNAH11
4788:DNAH10
4709:KIF26B
4704:KIF26A
4679:KIF21B
4674:KIF21A
4669:KIF20B
4664:KIF20A
4654:KIF18B
4649:KIF18A
4639:KIF16B
4624:KIF13B
4619:KIF13A
4418:TUBB4Q
4403:TUBB2C
4398:TUBB2B
4393:TUBB2A
4373:TUBA4A
4368:TUBA3E
4363:TUBA3D
4358:TUBA3C
4353:TUBA1C
4348:TUBA1B
4343:TUBA1A
4286:Type 5
4245:Nestin
4233:Type 4
4209:Desmin
4202:Type 3
3955:type I
3786:type I
3732:TRIOBP
3398:MYO18B
3393:MYO18A
3389:XVIII
3383:MYO15A
3118:Actins
2913:Q9Y4I1
2886:
2843:
2836:379173
2833:
2800:
2793:111140
2790:
2757:
2722:
2689:
2654:
2619:
2584:
2574:
2539:
2504:
2474:
2464:
2431:
2423:
2397:Nature
2386:
2351:
2341:
2308:
2275:
2267:
2237:
2162:
2114:
2106:
2062:
2013:
2006:111140
2003:
1964:
1954:
1912:
1902:
1853:
1787:
1777:
1769:
1726:
1716:
1708:
1660:
1650:
1642:
1501:Myosin
1424:DYNLL2
1420:RAB27A
1416:DYNLL1
1338:search
1336:PubMed
1179:Q99104
1160:Q9Y4I1
1056:Entrez
733:ruffle
570:BioGPS
157:105976
149:160777
5263:Talin
5246:MACF1
5214:Other
5173:SPTA1
5038:TEKT5
5033:TEKT4
5028:TEKT3
5023:TEKT2
5018:TEKT1
5001:DCTN1
4984:Other
4838:DNAL4
4833:DNAL1
4823:DNAI2
4818:DNAI1
4783:DNAH9
4778:DNAH8
4773:DNAH7
4768:DNAH6
4763:DNAH5
4758:DNAH3
4753:DNAH2
4748:DNAH1
4729:KIFC3
4724:KIFC2
4719:KIFC1
4714:KIF27
4699:KIF25
4694:KIF24
4689:KIF23
4684:KIF22
4659:KIF19
4644:KIF17
4634:KIF15
4629:KIF14
4614:KIF12
4609:KIF11
4589:KIF5C
4584:KIF5B
4579:KIF5A
4574:KIF4B
4569:KIF4A
4564:KIF3C
4559:KIF3B
4554:KIF2C
4549:KIF2A
4544:KIF1B
4539:KIF1A
4511:MAP1B
4506:MAP1A
4473:TUBE1
4468:TUBD1
4438:TUBG2
4433:TUBG1
4428:TUBB8
4423:TUBB6
4413:TUBB4
4408:TUBB3
4388:TUBB1
4378:TUBA8
3727:Espin
3688:Other
3675:Titin
3481:Other
3470:MYLL1
3465:MYLK2
3455:MYLIP
3440:MYL6B
3373:MYO10
3363:MYO9B
3358:MYO9A
3348:MYO7B
3343:MYO7A
3323:MYO5C
3318:MYO5B
3313:MYO5A
3303:MYO3B
3298:MYO3A
3288:MYH16
3283:MYH15
3278:MYH14
3273:MYH13
3268:MYH11
3263:MYH10
3248:MYH7B
3207:MYO1H
3202:MYO1G
3197:MYO1F
3192:MYO1E
3187:MYO1D
3182:MYO1C
3177:MYO1B
3172:MYO1A
3087:Human
2429:S2CID
2273:S2CID
2112:S2CID
1905:44240
1506:MYP5B
1484:KCNA5
1480:MYO5B
1428:Rab3A
1414:with
1388:MYO5A
1382:is a
1089:17918
1049:Mouse
1044:Human
1015:Amigo
422:Mouse
415:Human
362:Start
297:Mouse
261:Start
194:Human
173:MYO5A
165:20100
132:MYO5A
33:MYO5A
18:MYO5A
5347:ParM
5342:MreB
5337:FtsZ
5297:ACF7
5290:PKP2
5285:PKP1
5268:TLN1
5183:SPTB
5161:ANK3
5156:ANK2
5151:ANK1
5060:DNM3
5055:DNM2
5050:DNM1
4954:PCM1
4604:KIF9
4599:KIF7
4594:KIF6
4521:MAP4
4516:MAP2
4483:MAPs
4383:TUBB
4326:MAPs
4324:and
4265:NEFH
4260:NEFM
4255:NEFL
4214:GFAP
3862:none
3720:FLNC
3715:FLNB
3710:FLNA
3460:MYLK
3450:MYL9
3445:MYL7
3435:MYL6
3430:MYL5
3425:MYL4
3420:MYL3
3415:MYL2
3410:MYL1
3339:VII
3333:MYO6
3294:III
3258:MYH9
3253:MYH8
3243:MYH7
3238:MYH6
3233:MYH4
3228:MYH3
3223:MYH2
3218:MYH1
3100:ABPs
3098:and
3032:2ix7
3017:1w8j
3002:1w7j
2987:1w7i
2972:1oe9
2906:for
2884:PMID
2841:PMID
2798:PMID
2755:PMID
2720:PMID
2687:PMID
2652:PMID
2617:PMID
2582:PMID
2537:PMID
2502:PMID
2472:PMID
2421:PMID
2384:PMID
2349:PMID
2306:PMID
2265:PMID
2235:PMID
2104:PMID
2060:PMID
2011:PMID
1962:PMID
1910:PMID
1851:PMID
1814:2022
1785:PMID
1767:ISSN
1724:PMID
1706:ISSN
1658:PMID
1640:ISSN
1391:gene
1070:4644
474:pons
405:Bgee
353:Band
314:Chr.
252:Band
211:Chr.
145:OMIM
102:4D07
98:4LLI
94:4LX2
90:4LX1
86:4J5L
67:RCSB
64:PDBe
5111:GAN
5094:APC
4501:EB3
4496:EB2
4491:EB1
4297:A/C
3980:33B
3975:33A
3379:XV
3354:IX
3329:VI
3214:II
2904:PDB
2874:doi
2862:517
2831:PMC
2823:doi
2788:PMC
2780:doi
2745:doi
2741:277
2712:doi
2708:115
2677:doi
2673:277
2642:doi
2607:doi
2603:276
2572:PMC
2562:doi
2527:doi
2523:114
2494:doi
2462:PMC
2454:doi
2450:195
2413:doi
2401:400
2374:doi
2370:274
2339:PMC
2331:doi
2327:143
2298:doi
2294:252
2257:doi
2227:doi
2160:PMC
2152:doi
2096:doi
2084:293
2050:doi
2038:517
2001:PMC
1993:doi
1952:PMC
1944:doi
1900:PMC
1890:doi
1841:doi
1775:PMC
1759:doi
1755:114
1714:PMC
1696:doi
1692:286
1648:PMC
1630:doi
375:End
274:End
177:OMA
153:MGI
57:PDB
5378::
4307:B2
4302:B1
4295::
4171:80
4166:79
4161:78
4156:77
4151:76
4146:75
4141:74
4136:73
4131:72
4126:71
4110:40
4105:39
4100:28
4095:27
4090:26
4085:25
4080:24
4075:23
4050:86
4045:85
4040:84
4035:83
4030:82
4025:81
4005:38
4000:37
3995:36
3990:35
3985:34
3970:32
3965:31
3922:6C
3917:6B
3912:6A
3892:2A
3867:21
3855:18
3841:20
3836:19
3831:17
3826:16
3821:15
3816:14
3811:13
3806:12
3801:10
3405:LC
3369:X
3309:V
3168:I
3151:G2
3146:G1
3141:C1
3131:A2
3126:A1
2910::
2882:.
2872:.
2860:.
2856:.
2839:.
2829:.
2819:71
2817:.
2813:.
2796:.
2786:.
2776:13
2774:.
2770:.
2753:.
2739:.
2735:.
2718:.
2706:.
2702:.
2685:.
2671:.
2667:.
2650:.
2638:78
2636:.
2632:.
2615:.
2601:.
2597:.
2580:.
2570:.
2558:20
2556:.
2552:.
2535:.
2521:.
2517:.
2500:.
2490:63
2488:.
2470:.
2460:.
2448:.
2444:.
2427:.
2419:.
2411:.
2399:.
2382:.
2368:.
2364:.
2347:.
2337:.
2325:.
2321:.
2304:.
2292:.
2288:.
2271:.
2263:.
2253:16
2251:.
2233:.
2223:69
2221:.
2217:.
2187:.
2174:^
2158:.
2150:.
2138:.
2134:.
2110:.
2102:.
2094:.
2082:.
2058:.
2048:.
2036:.
2032:.
2009:.
1999:.
1989:13
1987:.
1983:.
1960:.
1950:.
1940:20
1938:.
1934:.
1922:^
1908:.
1898:.
1888:.
1878:91
1876:.
1872:.
1849:.
1837:19
1835:.
1831:.
1805:.
1783:.
1773:.
1765:.
1753:.
1749:.
1736:^
1722:.
1712:.
1704:.
1690:.
1686:.
1670:^
1656:.
1646:.
1638:.
1628:.
1616:.
1612:.
1598:^
1588:.
1570:.
1541:^
1520:^
1430:.
1422:,
1418:,
1393:.
1017:/
381:bp
368:bp
280:bp
267:bp
175:;
171::
167:;
163::
159:;
155::
151:;
147::
100:,
96:,
92:,
88:,
4017:/
3957:/
3932:8
3927:7
3907:5
3902:4
3897:3
3887:1
3879:/
3796:9
3788:/
3767:)
3762:,
3758:(
3668:2
3663:1
3639:2
3634:1
3610:4
3605:3
3600:2
3595:1
3581:4
3576:3
3571:2
3566:1
3554:3
3551:2
3548:1
3545:I
3540:2
3537:1
3534:C
3529:3
3526:2
3523:1
3520:T
3508:4
3503:3
3498:2
3493:1
3209:)
3136:B
3068:e
3061:t
3054:v
2947:e
2940:t
2933:v
2920:.
2890:.
2876::
2868::
2847:.
2825::
2804:.
2782::
2761:.
2747::
2726:.
2714::
2693:.
2679::
2658:.
2644::
2623:.
2609::
2588:.
2564::
2543:.
2529::
2508:.
2496::
2478:.
2456::
2435:.
2415::
2407::
2390:.
2376::
2355:.
2333::
2312:.
2300::
2279:.
2259::
2241:.
2229::
2197:.
2168:.
2154::
2146::
2140:7
2118:.
2098::
2090::
2066:.
2052::
2044::
2017:.
1995::
1968:.
1946::
1916:.
1892::
1884::
1857:.
1843::
1816:.
1791:.
1761::
1730:.
1698::
1664:.
1632::
1624::
1618:8
1592:.
1574:.
1475:.
299:)
196:)
179::
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.