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MYO7A

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299: 276: 173: 198: 305: 204: 1296:, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. Myosin VIIA is an unconventional myosin with the longest tail (1360 aa). The tail is expected to dimerize, resulting in a two-headed molecule. Unconventional myosins have diverse functions in 52: 2430:
Guilford P, Ayadi H, Blanchard S, Chaib H, Le Paslier D, Weissenbach J, Drira M, Petit C (June 1994). "A human gene responsible for neurosensory, non-syndromic recessive deafness is a candidate homologue of the mouse sh-1 gene".
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Kimberling WJ, Möller CG, Davenport S, Priluck IA, Beighton PH, Greenberg J, Reardon W, Weston MD, Kenyon JB, Grunkemeyer JA (December 1992). "Linkage of Usher syndrome type I gene (USH1B) to the long arm of chromosome 11".
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Weil D, Küssel P, Blanchard S, Lévy G, Levi-Acobas F, Drira M, Ayadi H, Petit C (June 1997). "The autosomal recessive isolated deafness, DFNB2, and the Usher 1B syndrome are allelic defects of the myosin-VIIA gene".
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Wagenaar M, ter Rahe B, van Aarem A, Huygen P, Admiraal R, Bleeker-Wagemakers E, Pinckers A, Kimberling W, Cremers C (November 1995). "Clinical findings in obligate carriers of type I Usher syndrome".
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Smith RJ, Berlin CI, Hejtmancik JF, Keats BJ, Kimberling WJ, Lewis RA, Möller CG, Pelias MZ, Tranebjaerg L (March 1994). "Clinical diagnosis of the Usher syndromes. Usher Syndrome Consortium".
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Weil D, Blanchard S, Kaplan J, Guilford P, Gibson F, Walsh J, Mburu P, Varela A, Levilliers J, Weston MD (March 1995). "Defective myosin VIIA gene responsible for Usher syndrome type 1B".
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Hasson T, Skowron JF, Gilbert DJ, Avraham KB, Perry WL, Bement WM, Anderson BL, Sherr EH, Chen ZY, Greene LA, Ward DC, Corey DP, Mooseker MS, Copeland NG, Jenkins NA (September 1996).
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Weston MD, Kelley PM, Overbeck LD, Wagenaar M, Orten DJ, Hasson T, Chen ZY, Corey D, Mooseker M, Sumegi J, Cremers C, Moller C, Jacobson SG, Gorin MB, Kimberling WJ (November 1996).
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Liu XZ, Walsh J, Tamagawa Y, Kitamura K, Nishizawa M, Steel KP, Brown SD (November 1997). "Autosomal dominant non-syndromic deafness caused by a mutation in the myosin VIIA gene".
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Lévy G, Levi-Acobas F, Blanchard S, Gerber S, Larget-Piet D, Chenal V, Liu XZ, Newton V, Steel KP, Brown SD, Munnich A, Kaplan J, Petit C, Weil D (January 1997).
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Liu XZ, Walsh J, Mburu P, Kendrick-Jones J, Cope MJ, Steel KP, Brown SD (June 1997). "Mutations in the myosin VIIA gene cause non-syndromic recessive deafness".
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type 1B, a combined deafness/blindness disorder. Affected individuals are typically profoundly deaf at birth and then undergo progressive retinal degeneration.
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Kelley PM, Weston MD, Chen ZY, Orten DJ, Hasson T, Overbeck LD, Pinnt J, Talmadge CB, Ing P, Mooseker MS, Corey D, Sumegi J, Kimberling WJ (February 1997).
964: 945: 134: 2562:"Human myosin VIIA responsible for the Usher 1B syndrome: a predicted membrane-associated motor protein expressed in developing sensory epithelia" 2615:"A gene for a dominant form of non-syndromic sensorineural deafness (DFNA11) maps within the region containing the DFNB2 recessive deafness gene" 2228:"Human Usher 1B/mouse shaker-1: the retinal phenotype discrepancy explained by the presence/absence of myosin VIIA in the photoreceptor cells" 5245: 2208: 1729: 3558: 1711: 49: 2923: 1289:
binding molecular motors that use the enzymatic conversion of ATP - ADP + inorganic phosphate (Pi) to provide the energy for movement.
298: 1208: 1215: 2263:"Mutation profile of all 49 exons of the human myosin VIIA gene, and haplotype analysis, in Usher 1B families from diverse origins" 275: 1475: 2648:
Chen ZY, Hasson T, Kelley PM, Schwender BJ, Schwartz MF, Ramakrishnan M, Kimberling WJ, Mooseker MS, Corey DP (September 1996).
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Liu XZ, Hope C, Walsh J, Newton V, Ke XM, Liang CY, Xu LR, Zhou JM, Trump D, Steel KP, Bundey S, Brown SD (September 1998).
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Weil D, Levy G, Sahly I, Levi-Acobas F, Blanchard S, El-Amraoui A, Crozet F, Philippe H, Abitbol M, Petit C (April 1996).
1673: 114: 3486: 1544: 1465: 311: 210: 4957: 304: 203: 5190: 1399: 1009: 122: 2650:"Molecular cloning and domain structure of human myosin-VIIa, the gene product defective in Usher syndrome 1B" 1961: 2181:
Wolfrum U (2003). "The Cellular Function of the Usher Gene Product Myosin VIIa is Specified by Its Ligands".
1947: 1933: 5265: 5255: 2462:"Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types" 2010:
Gerdin AK (2010). "The Sanger Mouse Genetics Programme: High throughput characterisation of knockout mice".
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cells and are primarily thought to be involved in the movement or linkage of intra-cellular membranes and
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Adato A, Weil D, Kalinski H, Pel-Or Y, Ayadi H, Petit C, Korostishevsky M, Bonne-Tamir B (October 1997).
1989: 5260: 3609: 2963: 2057: 1891: 186: 2379:"Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1B" 2306:"Mutations in the myosin VIIA gene cause a wide phenotypic spectrum, including atypical Usher syndrome" 1975: 1905: 1877: 3878: 2573: 2473: 2390: 1800: 1645: 1445: 1293: 2191: 101: 5185: 3818: 1187: 1183: 1179: 1158: 1154: 1120: 1116: 1112: 1091: 1087: 1083: 1919: 1624:
bone morphology. Homozygous mutant mice of both sex displayed various abnormalities in a modified
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to the actin cytoskeleton via interactions mediated by their highly divergent tail domains.
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Tamagawa Y, Kitamura K, Ishida T, Ishikawa K, Tanaka H, Tsuji S, Nishizawa M (June 1996).
366: 2720:"Myosin VIIA gene: heterogeneity of the mutations responsible for Usher syndrome type IB" 1292:
Myosins are mechanochemical proteins characterized by the presence of a motor domain, an
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have been used in the study of MYO7A function. A spontaneous mutant mouse line, called
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Hasson T, Heintzelman MB, Santos-Sacchi J, Corey DP, Mooseker MS (October 1995).
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National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
1534: 1485: 2908: 2755:"The genomic structure of the gene defective in Usher syndrome type Ib (MYO7A)" 2566:
Proceedings of the National Academy of Sciences of the United States of America
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Proceedings of the National Academy of Sciences of the United States of America
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Proceedings of the National Academy of Sciences of the United States of America
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to determine the effects of deletion. Twenty three tests were carried out on
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el-Amraoui A, Sahly I, Picaud S, Sahel J, Abitbol M, Petit C (August 1996).
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mice displayed a decreased body weight, a decrease in body fat, improved
1239: 1054: 1035: 5165: 5119: 5009: 4939: 4908: 4838: 4833: 4797: 4792: 4787: 4754: 4724: 4719: 4714: 4709: 4394: 4326: 4321: 4316: 4311: 4306: 4198: 4135: 3623: 3568: 3509: 3492: 3453: 2939: 2884: 2847: 2809: 2166: 2156: 2145: 2135: 2044: 1271: 1021: 976: 2685:"Myosin VIIA mutation screening in 189 Usher syndrome type 1 patients" 2535: 71: 5084: 5066: 5061: 5056: 5051: 5041: 4876: 4769: 4764: 4749: 4744: 4656: 4602: 4567: 4542: 4537: 4532: 4527: 4517: 4512: 4502: 4487: 4482: 4364: 4359: 4354: 4266: 4256: 4236: 4221: 4216: 4211: 4206: 4072: 3843: 3838: 3595: 3261: 3256: 3246: 3024: 1812: 1625: 1613: 1606: 1354: 1328: 1320: 1312: 1308: 1282: 1223: 931: 2460:
Bement WM, Hasson T, Wirth JA, Cheney RE, Mooseker MS (July 1994).
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was generated. Male and female animals underwent a standardized
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test, including abnormal gait, tail dragging and an absence of
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MYO7A is expressed in a number of mammalian tissues, including
2073:"The mouse genetics toolkit: revealing function and mechanism" 2151:
Overview of all the structural information available in the
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Overview of all the structural information available in the
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mice and ten significant abnormalities were observed. Male
105:, DFNA11, DFNB2, MYOVIIA, MYU7A, NSRD2, USH1B, myosin VIIA 374: 2071:
van der Weyden L, White JK, Adams DJ, Logan DW (2011).
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GeneReviews/NCBI/NIH/UW entry on Usher Syndrome Type I
1749:"Mapping of unconventional myosins in mouse and human" 539: 5178: 5077: 4983: 4938: 4847: 4826: 4778: 4601: 4393: 4345: 4197: 4183: 4149: 4096: 4065: 4045: 3924: 3806: 3637: 3619: 3608: 3551: 3344: 3023: 2980: 2971: 2957: 2950: 1172: 1143: 1105: 1072: 1690: 1688: 1686: 1669: 1667: 1665: 775:inner ear receptor cell stereocilium organization 321: 220: 2005: 2003: 2001: 1999: 1281:. Myosin VIIA is a member of the unconventional 820:inner ear auditory receptor cell differentiation 810:auditory receptor cell stereocilium organization 16:Protein-coding gene in the species Homo sapiens 1695:GRCm38: Ensembl release 89: ENSMUSG00000030761 2924: 1786: 1784: 8: 1674:GRCh38: Ensembl release 89: ENSG00000137474 4194: 3634: 3616: 2977: 2968: 2954: 2931: 2917: 2909: 2165:(Mouse Unconventional myosin-VIIa) at the 2144:(Human Unconventional myosin-VIIa) at the 905: 565: 362: 261: 158: 60: 2770: 2735: 2700: 2665: 2630: 2595: 2585: 2534: 2495: 2485: 2412: 2402: 2329: 2286: 2243: 2190: 2098: 2088: 1764: 790:post-embryonic animal organ morphogenesis 1892:"Neurological assessment data for Myo7a" 1948:"Glucose tolerance test data for Myo7a" 1661: 855:inner ear receptor cell differentiation 20: 1934:"Indirect calorimetry data for Myo7a" 1285:superfamily of proteins. Myosins are 326: 287: 282: 225: 184: 179: 7: 2515:American Journal of Medical Genetics 1844:American Journal of Medical Genetics 785:sensory perception of light stimulus 1990:"Clinical chemistry data for Myo7a" 2689:American Journal of Human Genetics 2310:American Journal of Human Genetics 2267:American Journal of Human Genetics 2047:, Wellcome Trust Sanger Institute. 1992:. Wellcome Trust Sanger Institute. 1978:. Wellcome Trust Sanger Institute. 1964:. Wellcome Trust Sanger Institute. 1950:. Wellcome Trust Sanger Institute. 1936:. Wellcome Trust Sanger Institute. 1922:. Wellcome Trust Sanger Institute. 1908:. Wellcome Trust Sanger Institute. 1894:. Wellcome Trust Sanger Institute. 1880:. Wellcome Trust Sanger Institute. 1169: 1140: 1102: 1069: 1045: 1026: 1000: 981: 955: 936: 840:eye photoreceptor cell development 653:protein-containing complex binding 544: 482:choroid plexus of fourth ventricle 462: 400: 379: 14: 1274:that in humans is encoded by the 593:protein homodimerization activity 3559:Wiskott–Aldrich syndrome protein 310: 303: 297: 274: 209: 202: 196: 171: 4780:Microtubule organising proteins 2024:10.1111/j.1755-3768.2010.4142.x 1582: 1574: 1566: 1558: 1548: 1538: 1528: 1515: 1505: 1497: 1489: 1479: 1469: 1459: 1449: 1439: 1429: 1419: 1411: 1403: 1393: 1385: 1377: 860:intracellular protein transport 800:mechanoreceptor differentiation 699:photoreceptor connecting cilium 598:protein domain specific binding 1906:"Grip strength data for Myo7a" 528:More reference expression data 1: 4827:Microtubule severing proteins 2362:10.1016/S0888-7543(05)80121-1 875:actin filament-based movement 295: 194: 5246:Genes on human chromosome 11 3487:actin depolymerizing factors 2201:10.1007/978-1-4615-0067-4_17 1976:"Radiography data for Myo7a" 1878:"Body weight data for Myo7a" 1588:All tests and analysis from 1545:Peripheral blood lymphocytes 825:cell projection organization 780:pigment granule localization 613:microfilament motor activity 510:Epithelium of choroid plexus 4965:Plakoglobin (gamma catenin) 1466:Auditory brainstem response 689:photoreceptor outer segment 679:photoreceptor inner segment 628:cytoskeletal motor activity 448:paraflocculus of cerebellum 5287: 2058:"Mouse Genome Informatics" 1920:"Hot plate data for Myo7a" 1587: 880:microtubule-based movement 658:protein N-terminus binding 638:microtubule motor activity 502:retinal pigment epithelium 5221: 1730:"Mouse PubMed Reference:" 1712:"Human PubMed Reference:" 1644:and a number of abnormal 1572:Tail epidermis wholemount 1254: 1249: 1245: 1238: 1222: 1203: 1176: 1147: 1136: 1109: 1076: 1065: 1052: 1048: 1033: 1029: 1020: 1007: 1003: 988: 984: 975: 962: 958: 943: 939: 930: 915: 908: 904: 888: 805:pigment granule transport 568: 564: 552: 547: 538: 525: 474: 465: 412: 403: 373: 365: 361: 344: 331: 294: 273: 264: 260: 243: 230: 193: 170: 161: 157: 112: 109: 99: 92: 87: 68: 63: 46: 41: 36: 32: 28: 23: 5191:Prokaryotic cytoskeleton 2724:Human Molecular Genetics 2619:Human Molecular Genetics 2433:Human Molecular Genetics 2232:Human Molecular Genetics 2090:10.1186/gb-2011-12-6-224 1209:Chr 11: 77.13 – 77.22 Mb 2527:10.1002/ajmg.1320590319 2487:10.1073/pnas.91.14.6549 2404:10.1073/pnas.92.21.9815 1856:10.1002/ajmg.1320500107 1636:, an increased thermal 1409:Neurological assessment 1359:mutant mouse phenotype 835:inner ear morphogenesis 2772:10.1006/geno.1996.4545 2667:10.1006/geno.1996.0489 2587:10.1073/pnas.93.8.3232 2045:Mouse Resources Portal 1766:10.1006/geno.1996.0488 1456:Glucose tolerance test 1216:Chr 7: 97.7 – 97.77 Mb 815:phagolysosome assembly 729:upper tip-link density 719:apical plasma membrane 648:actin filament binding 5271:Genes mutated in mice 3811:(hard alpha-keratins) 3642:(soft alpha-keratins) 2183:Retinal Degenerations 1962:"DEXA data for Myo7a" 1335:Clinical significance 865:lysosome organization 850:inner ear development 490:stroma of bone marrow 187:Chromosome 11 (human) 5226:cytoskeletal defects 5186:Major sperm proteins 2245:10.1093/hmg/5.8.1171 2012:Acta Ophthalmologica 1646:indirect calorimetry 1446:Indirect calorimetry 1294:actin-binding domain 416:right adrenal cortex 328:7 E1|7 53.57 cM 289:Chromosome 7 (mouse) 64:List of PDB id codes 37:Available structures 3639:Epithelial keratins 2737:10.1093/hmg/6.1.111 2632:10.1093/hmg/5.6.849 2578:1996PNAS...93.3232W 2478:1994PNAS...91.6549B 2445:10.1093/hmg/3.6.989 2395:1995PNAS...92.9815H 1805:1995Natur.374...60W 1580:Skin Histopathology 1360: 643:microtubule binding 432:right lobe of liver 424:left adrenal cortex 2885:10.1038/ng1197-268 2848:10.1038/ng0697-191 2810:10.1038/ng0697-188 1650:clinical chemistry 1642:hearing impairment 1512:Clinical chemistry 1355: 1010:ENSMUSG00000030761 770:sensory perception 763:Biological process 724:myosin VII complex 709:lysosomal membrane 667:Cellular component 608:calmodulin binding 583:nucleotide binding 576:Molecular function 440:anterior pituitary 420:left adrenal gland 5233: 5232: 5174: 5173: 4934: 4933: 4179: 4178: 4061: 4060: 3604: 3603: 3547: 3546: 2210:978-1-4613-4909-9 1618:glucose tolerance 1603:phenotypic screen 1592: 1591: 1555:Micronucleus test 1339:Mutations in the 1323:and the ciliated 1265: 1264: 1261: 1260: 1234: 1233: 1199: 1198: 1166: 1165: 1132: 1131: 1099: 1098: 1061: 1060: 1042: 1041: 1016: 1015: 997: 996: 971: 970: 952: 951: 900: 899: 870:visual perception 830:equilibrioception 754:stereocilium base 560: 559: 556: 555: 534: 533: 521: 520: 506:choroidal fissure 459: 458: 357: 356: 256: 255: 151:MYO7A - orthologs 83: 82: 79: 78: 47:Ortholog search: 5278: 4195: 3635: 3617: 2978: 2969: 2955: 2933: 2926: 2919: 2910: 2904: 2867: 2829: 2792: 2774: 2749: 2739: 2714: 2704: 2679: 2669: 2644: 2634: 2609: 2599: 2589: 2556: 2538: 2509: 2499: 2489: 2456: 2426: 2416: 2406: 2373: 2343: 2333: 2300: 2290: 2257: 2247: 2222: 2194: 2113: 2112: 2102: 2092: 2068: 2062: 2061: 2054: 2048: 2042: 2036: 2035: 2007: 1994: 1993: 1986: 1980: 1979: 1972: 1966: 1965: 1958: 1952: 1951: 1944: 1938: 1937: 1930: 1924: 1923: 1916: 1910: 1909: 1902: 1896: 1895: 1888: 1882: 1881: 1874: 1868: 1867: 1839: 1833: 1832: 1813:10.1038/374060a0 1788: 1779: 1778: 1768: 1744: 1738: 1737: 1726: 1720: 1719: 1708: 1702: 1692: 1681: 1671: 1632:, a decrease in 1495:Body temperature 1361: 1247: 1246: 1218: 1211: 1194: 1170: 1161: 1141: 1137:RefSeq (protein) 1127: 1103: 1094: 1070: 1046: 1027: 1001: 982: 956: 937: 906: 588:spectrin binding 566: 545: 530: 486:Ileal epithelium 478:fourth ventricle 470: 468:Top expressed in 463: 408: 406:Top expressed in 401: 380: 363: 353: 340: 329: 314: 307: 301: 290: 278: 262: 252: 239: 228: 213: 206: 200: 189: 175: 159: 153: 104: 97: 74: 61: 55: 34: 33: 21: 5286: 5285: 5281: 5280: 5279: 5277: 5276: 5275: 5236: 5235: 5234: 5229: 5217: 5170: 5073: 4979: 4930: 4843: 4822: 4774: 4597: 4389: 4341: 4187: 4175: 4145: 4092: 4057: 4041: 3925:Ungrouped alpha 3920: 3810: 3802: 3641: 3627: 3621: 3611: 3600: 3543: 3340: 3019: 2961: 2946: 2937: 2907: 2873:Nature Genetics 2870: 2836:Nature Genetics 2832: 2798:Nature Genetics 2795: 2752: 2717: 2682: 2647: 2612: 2559: 2512: 2472:(14): 6549–53. 2459: 2429: 2376: 2346: 2303: 2260: 2225: 2211: 2192:10.1.1.501.2021 2180: 2176: 2174:Further reading 2122: 2117: 2116: 2070: 2069: 2065: 2056: 2055: 2051: 2043: 2039: 2009: 2008: 1997: 1988: 1987: 1983: 1974: 1973: 1969: 1960: 1959: 1955: 1946: 1945: 1941: 1932: 1931: 1927: 1918: 1917: 1913: 1904: 1903: 1899: 1890: 1889: 1885: 1876: 1875: 1871: 1841: 1840: 1836: 1790: 1789: 1782: 1746: 1745: 1741: 1728: 1727: 1723: 1710: 1709: 1705: 1693: 1684: 1672: 1663: 1658: 1595:Model organisms 1525:immunoglobulins 1353: 1351:Model organisms 1343:gene cause the 1337: 1256:View/Edit Mouse 1251:View/Edit Human 1214: 1207: 1204:Location (UCSC) 1190: 1186: 1182: 1178: 1157: 1153: 1149: 1123: 1119: 1115: 1111: 1090: 1086: 1082: 1078: 991:ENSG00000137474 884: 758: 662: 618:protein binding 526: 517: 512: 508: 504: 500: 496: 492: 488: 484: 480: 466: 455: 450: 446: 442: 438: 434: 430: 426: 422: 418: 404: 348: 335: 327: 317: 316: 315: 308: 288: 265:Gene location ( 247: 234: 226: 216: 215: 214: 207: 185: 162:Gene location ( 113: 100: 93: 70: 48: 17: 12: 11: 5: 5284: 5282: 5274: 5273: 5268: 5266:Human proteins 5263: 5258: 5256:Motor proteins 5253: 5248: 5238: 5237: 5231: 5230: 5222: 5219: 5218: 5216: 5215: 5214: 5213: 5208: 5203: 5198: 5188: 5182: 5180: 5176: 5175: 5172: 5171: 5169: 5168: 5163: 5158: 5157: 5156: 5151: 5141: 5136: 5135: 5134: 5124: 5123: 5122: 5117: 5112: 5107: 5102: 5097: 5092: 5090:Corneodesmosin 5081: 5079: 5075: 5074: 5072: 5071: 5070: 5069: 5064: 5059: 5054: 5049: 5044: 5039: 5029: 5028: 5027: 5022: 5017: 5007: 5002: 5001: 5000: 4989: 4987: 4981: 4980: 4978: 4977: 4972: 4967: 4962: 4961: 4960: 4950: 4944: 4942: 4936: 4935: 4932: 4931: 4929: 4928: 4927: 4926: 4921: 4916: 4906: 4905: 4904: 4899: 4894: 4889: 4884: 4874: 4869: 4868: 4867: 4857: 4851: 4849: 4845: 4844: 4842: 4841: 4836: 4830: 4828: 4824: 4823: 4821: 4820: 4815: 4810: 4805: 4800: 4795: 4790: 4784: 4782: 4776: 4775: 4773: 4772: 4767: 4762: 4757: 4752: 4747: 4742: 4737: 4732: 4727: 4722: 4717: 4712: 4705: 4704: 4699: 4694: 4689: 4684: 4679: 4674: 4669: 4664: 4659: 4654: 4649: 4644: 4639: 4634: 4629: 4624: 4619: 4614: 4607: 4605: 4599: 4598: 4596: 4595: 4590: 4585: 4580: 4575: 4570: 4565: 4560: 4555: 4550: 4545: 4540: 4535: 4530: 4525: 4520: 4515: 4510: 4505: 4500: 4495: 4490: 4485: 4480: 4475: 4470: 4465: 4460: 4455: 4450: 4445: 4440: 4435: 4430: 4425: 4420: 4415: 4410: 4405: 4399: 4397: 4391: 4390: 4388: 4387: 4382: 4377: 4372: 4367: 4362: 4357: 4351: 4349: 4343: 4342: 4340: 4339: 4334: 4329: 4324: 4319: 4314: 4309: 4304: 4299: 4294: 4289: 4284: 4279: 4274: 4269: 4264: 4259: 4254: 4249: 4244: 4239: 4234: 4229: 4224: 4219: 4214: 4209: 4203: 4201: 4192: 4181: 4180: 4177: 4176: 4174: 4173: 4168: 4163: 4157:Nuclear lamins 4153: 4151: 4147: 4146: 4144: 4143: 4138: 4133: 4132: 4131: 4126: 4121: 4111: 4106: 4100: 4098: 4094: 4093: 4091: 4090: 4085: 4080: 4075: 4069: 4067: 4063: 4062: 4059: 4058: 4056: 4055: 4049: 4047: 4043: 4042: 4040: 4039: 4038: 4037: 4032: 4027: 4022: 4017: 4012: 4007: 4002: 3997: 3992: 3979: 3978: 3977: 3976: 3971: 3966: 3961: 3956: 3951: 3946: 3941: 3928: 3926: 3922: 3921: 3919: 3918: 3917: 3916: 3911: 3906: 3901: 3896: 3891: 3874: 3873: 3872: 3871: 3866: 3861: 3856: 3851: 3846: 3841: 3836: 3831: 3814: 3812: 3804: 3803: 3801: 3800: 3799: 3798: 3793: 3788: 3783: 3778: 3773: 3768: 3763: 3758: 3753: 3736: 3735: 3734: 3733: 3723: 3722: 3721: 3709: 3708: 3707: 3702: 3697: 3692: 3687: 3682: 3677: 3672: 3667: 3662: 3645: 3643: 3632: 3614: 3606: 3605: 3602: 3601: 3599: 3598: 3593: 3588: 3587: 3586: 3581: 3576: 3566: 3561: 3555: 3553: 3549: 3548: 3545: 3544: 3542: 3541: 3536: 3535: 3534: 3529: 3519: 3514: 3513: 3512: 3507: 3506: 3505: 3500: 3483: 3481:Arp2/3 complex 3478: 3477: 3476: 3471: 3466: 3461: 3450: 3449: 3448: 3447: 3442: 3437: 3432: 3422: 3421: 3420: 3406: 3395: 3376: 3375: 3374: 3369: 3364: 3359: 3348: 3346: 3342: 3341: 3339: 3338: 3337: 3336: 3331: 3326: 3321: 3316: 3311: 3306: 3301: 3296: 3291: 3286: 3281: 3276: 3266: 3265: 3264: 3259: 3251: 3250: 3249: 3241: 3240: 3239: 3231: 3230: 3229: 3224: 3216: 3215: 3214: 3209: 3201: 3200: 3199: 3191: 3190: 3189: 3184: 3179: 3171: 3170: 3169: 3164: 3156: 3155: 3154: 3149: 3144: 3139: 3134: 3129: 3124: 3119: 3114: 3109: 3104: 3099: 3094: 3089: 3084: 3076: 3075: 3074: 3068: 3063: 3058: 3053: 3048: 3043: 3038: 3029: 3027: 3021: 3020: 3018: 3017: 3012: 3007: 3002: 2997: 2992: 2986: 2984: 2975: 2966: 2959:Microfilaments 2952: 2948: 2947: 2938: 2936: 2935: 2928: 2921: 2913: 2906: 2905: 2868: 2830: 2793: 2750: 2715: 2695:(5): 1074–83. 2680: 2645: 2610: 2557: 2510: 2457: 2427: 2389:(21): 9815–9. 2374: 2344: 2322:10.1086/302026 2301: 2279:10.1086/514899 2258: 2223: 2209: 2177: 2175: 2172: 2171: 2170: 2149: 2128: 2121: 2120:External links 2118: 2115: 2114: 2077:Genome Biology 2063: 2049: 2037: 1995: 1981: 1967: 1953: 1939: 1925: 1911: 1897: 1883: 1869: 1834: 1799:(6517): 60–1. 1780: 1739: 1721: 1703: 1682: 1660: 1659: 1657: 1654: 1638:pain threshold 1590: 1589: 1585: 1584: 1581: 1577: 1576: 1573: 1569: 1568: 1565: 1561: 1560: 1557: 1551: 1550: 1547: 1541: 1540: 1537: 1531: 1530: 1527: 1518: 1517: 1514: 1508: 1507: 1504: 1503:Eye morphology 1500: 1499: 1496: 1492: 1491: 1488: 1482: 1481: 1478: 1472: 1471: 1468: 1462: 1461: 1458: 1452: 1451: 1448: 1442: 1441: 1438: 1432: 1431: 1428: 1422: 1421: 1418: 1414: 1413: 1410: 1406: 1405: 1402: 1396: 1395: 1392: 1388: 1387: 1384: 1380: 1379: 1376: 1369: 1368: 1365: 1364:Characteristic 1352: 1349: 1345:Usher syndrome 1336: 1333: 1263: 1262: 1259: 1258: 1253: 1243: 1242: 1236: 1235: 1232: 1231: 1229: 1227: 1220: 1219: 1212: 1205: 1201: 1200: 1197: 1196: 1174: 1173: 1167: 1164: 1163: 1145: 1144: 1138: 1134: 1133: 1130: 1129: 1107: 1106: 1100: 1097: 1096: 1074: 1073: 1067: 1063: 1062: 1059: 1058: 1050: 1049: 1043: 1040: 1039: 1031: 1030: 1024: 1018: 1017: 1014: 1013: 1005: 1004: 998: 995: 994: 986: 985: 979: 973: 972: 969: 968: 960: 959: 953: 950: 949: 941: 940: 934: 928: 927: 922: 917: 913: 912: 902: 901: 898: 897: 886: 885: 883: 882: 877: 872: 867: 862: 857: 852: 847: 842: 837: 832: 827: 822: 817: 812: 807: 802: 797: 792: 787: 782: 777: 772: 766: 764: 760: 759: 757: 756: 751: 746: 741: 739:myosin complex 736: 731: 726: 721: 716: 711: 706: 701: 696: 691: 686: 681: 676: 670: 668: 664: 663: 661: 660: 655: 650: 645: 640: 635: 630: 625: 620: 615: 610: 605: 600: 595: 590: 585: 579: 577: 573: 572: 562: 561: 558: 557: 554: 553: 550: 549: 542: 536: 535: 532: 531: 523: 522: 519: 518: 516: 515: 511: 507: 503: 499: 495: 491: 487: 483: 479: 475: 472: 471: 460: 457: 456: 454: 453: 449: 445: 441: 437: 433: 429: 425: 421: 417: 413: 410: 409: 397: 396: 388: 377: 371: 370: 367:RNA expression 359: 358: 355: 354: 346: 342: 341: 333: 330: 325: 319: 318: 309: 302: 296: 292: 291: 286: 280: 279: 271: 270: 258: 257: 254: 253: 245: 241: 240: 232: 229: 224: 218: 217: 208: 201: 195: 191: 190: 183: 177: 176: 168: 167: 155: 154: 111: 107: 106: 98: 90: 89: 85: 84: 81: 80: 77: 76: 66: 65: 57: 56: 45: 39: 38: 30: 29: 26: 25: 15: 13: 10: 9: 6: 4: 3: 2: 5283: 5272: 5269: 5267: 5264: 5262: 5259: 5257: 5254: 5252: 5249: 5247: 5244: 5243: 5241: 5228: 5227: 5220: 5212: 5209: 5207: 5204: 5202: 5199: 5197: 5194: 5193: 5192: 5189: 5187: 5184: 5183: 5181: 5177: 5167: 5164: 5162: 5159: 5155: 5152: 5150: 5147: 5146: 5145: 5142: 5140: 5137: 5133: 5130: 5129: 5128: 5125: 5121: 5118: 5116: 5113: 5111: 5108: 5106: 5103: 5101: 5098: 5096: 5093: 5091: 5088: 5087: 5086: 5083: 5082: 5080: 5076: 5068: 5065: 5063: 5060: 5058: 5055: 5053: 5050: 5048: 5045: 5043: 5040: 5038: 5035: 5034: 5033: 5030: 5026: 5023: 5021: 5018: 5016: 5013: 5012: 5011: 5008: 5006: 5003: 4999: 4996: 4995: 4994: 4991: 4990: 4988: 4986: 4982: 4976: 4973: 4971: 4970:Delta catenin 4968: 4966: 4963: 4959: 4956: 4955: 4954: 4951: 4949: 4948:Alpha catenin 4946: 4945: 4943: 4941: 4937: 4925: 4922: 4920: 4917: 4915: 4912: 4911: 4910: 4907: 4903: 4900: 4898: 4895: 4893: 4890: 4888: 4885: 4883: 4880: 4879: 4878: 4875: 4873: 4870: 4866: 4863: 4862: 4861: 4858: 4856: 4853: 4852: 4850: 4846: 4840: 4837: 4835: 4832: 4831: 4829: 4825: 4819: 4816: 4814: 4811: 4809: 4806: 4804: 4801: 4799: 4796: 4794: 4791: 4789: 4786: 4785: 4783: 4781: 4777: 4771: 4768: 4766: 4763: 4761: 4758: 4756: 4753: 4751: 4748: 4746: 4743: 4741: 4738: 4736: 4733: 4731: 4728: 4726: 4723: 4721: 4718: 4716: 4713: 4711: 4708:cytoplasmic: 4707: 4706: 4703: 4700: 4698: 4695: 4693: 4690: 4688: 4685: 4683: 4680: 4678: 4675: 4673: 4670: 4668: 4665: 4663: 4660: 4658: 4655: 4653: 4650: 4648: 4645: 4643: 4640: 4638: 4635: 4633: 4630: 4628: 4625: 4623: 4620: 4618: 4615: 4613: 4609: 4608: 4606: 4604: 4600: 4594: 4591: 4589: 4586: 4584: 4581: 4579: 4576: 4574: 4571: 4569: 4566: 4564: 4561: 4559: 4556: 4554: 4551: 4549: 4546: 4544: 4541: 4539: 4536: 4534: 4531: 4529: 4526: 4524: 4521: 4519: 4516: 4514: 4511: 4509: 4506: 4504: 4501: 4499: 4496: 4494: 4491: 4489: 4486: 4484: 4481: 4479: 4476: 4474: 4471: 4469: 4466: 4464: 4461: 4459: 4456: 4454: 4451: 4449: 4446: 4444: 4441: 4439: 4436: 4434: 4431: 4429: 4426: 4424: 4421: 4419: 4416: 4414: 4411: 4409: 4406: 4404: 4401: 4400: 4398: 4396: 4392: 4386: 4383: 4381: 4378: 4376: 4373: 4371: 4368: 4366: 4363: 4361: 4358: 4356: 4353: 4352: 4350: 4348: 4344: 4338: 4335: 4333: 4330: 4328: 4325: 4323: 4320: 4318: 4315: 4313: 4310: 4308: 4305: 4303: 4300: 4298: 4295: 4293: 4290: 4288: 4285: 4283: 4280: 4278: 4275: 4273: 4270: 4268: 4265: 4263: 4260: 4258: 4255: 4253: 4250: 4248: 4245: 4243: 4240: 4238: 4235: 4233: 4230: 4228: 4225: 4223: 4220: 4218: 4215: 4213: 4210: 4208: 4205: 4204: 4202: 4200: 4196: 4193: 4191: 4186: 4182: 4172: 4169: 4167: 4164: 4162: 4158: 4155: 4154: 4152: 4148: 4142: 4139: 4137: 4134: 4130: 4127: 4125: 4122: 4120: 4117: 4116: 4115: 4114:Neurofilament 4112: 4110: 4107: 4105: 4102: 4101: 4099: 4095: 4089: 4086: 4084: 4081: 4079: 4076: 4074: 4071: 4070: 4068: 4064: 4054: 4051: 4050: 4048: 4044: 4036: 4033: 4031: 4028: 4026: 4023: 4021: 4018: 4016: 4013: 4011: 4008: 4006: 4003: 4001: 3998: 3996: 3993: 3991: 3988: 3987: 3986: 3985: 3984:chromosome 12 3981: 3980: 3975: 3972: 3970: 3967: 3965: 3962: 3960: 3957: 3955: 3952: 3950: 3947: 3945: 3942: 3940: 3937: 3936: 3935: 3934: 3933:chromosome 17 3930: 3929: 3927: 3923: 3915: 3912: 3910: 3907: 3905: 3902: 3900: 3897: 3895: 3892: 3890: 3887: 3886: 3885: 3884: 3883:chromosome 12 3880: 3876: 3875: 3870: 3867: 3865: 3862: 3860: 3857: 3855: 3852: 3850: 3847: 3845: 3842: 3840: 3837: 3835: 3832: 3830: 3827: 3826: 3825: 3824: 3823:chromosome 17 3820: 3816: 3815: 3813: 3809: 3808:Hair keratins 3805: 3797: 3794: 3792: 3789: 3787: 3784: 3782: 3779: 3777: 3774: 3772: 3769: 3767: 3764: 3762: 3759: 3757: 3754: 3752: 3749: 3748: 3747: 3746: 3745:chromosome 12 3742: 3738: 3737: 3732: 3729: 3728: 3727: 3724: 3720: 3717: 3716: 3715: 3714: 3713:chromosome 12 3710: 3706: 3703: 3701: 3698: 3696: 3693: 3691: 3688: 3686: 3683: 3681: 3678: 3676: 3673: 3671: 3668: 3666: 3663: 3661: 3658: 3657: 3656: 3655: 3654:chromosome 17 3651: 3647: 3646: 3644: 3640: 3636: 3633: 3630: 3625: 3618: 3615: 3613: 3610:Intermediate 3607: 3597: 3594: 3592: 3589: 3585: 3582: 3580: 3577: 3575: 3572: 3571: 3570: 3567: 3565: 3562: 3560: 3557: 3556: 3554: 3550: 3540: 3537: 3533: 3530: 3528: 3525: 3524: 3523: 3520: 3518: 3515: 3511: 3508: 3504: 3501: 3499: 3496: 3495: 3494: 3491: 3490: 3489: 3488: 3484: 3482: 3479: 3475: 3472: 3470: 3467: 3465: 3462: 3460: 3457: 3456: 3455: 3452: 3451: 3446: 3443: 3441: 3438: 3436: 3433: 3431: 3428: 3427: 3426: 3423: 3419: 3416: 3413: 3410: 3407: 3405: 3402: 3399: 3396: 3394: 3391: 3388: 3385: 3382: 3381: 3380: 3377: 3373: 3370: 3368: 3365: 3363: 3360: 3358: 3355: 3354: 3353: 3350: 3349: 3347: 3343: 3335: 3332: 3330: 3327: 3325: 3322: 3320: 3317: 3315: 3312: 3310: 3307: 3305: 3302: 3300: 3297: 3295: 3292: 3290: 3287: 3285: 3282: 3280: 3277: 3275: 3272: 3271: 3270: 3267: 3263: 3260: 3258: 3255: 3254: 3252: 3248: 3245: 3244: 3242: 3238: 3235: 3234: 3232: 3228: 3225: 3223: 3220: 3219: 3217: 3213: 3210: 3208: 3205: 3204: 3202: 3198: 3195: 3194: 3192: 3188: 3185: 3183: 3180: 3178: 3175: 3174: 3172: 3168: 3165: 3163: 3160: 3159: 3157: 3153: 3150: 3148: 3145: 3143: 3140: 3138: 3135: 3133: 3130: 3128: 3125: 3123: 3120: 3118: 3115: 3113: 3110: 3108: 3105: 3103: 3100: 3098: 3095: 3093: 3090: 3088: 3085: 3083: 3080: 3079: 3077: 3072: 3069: 3067: 3064: 3062: 3059: 3057: 3054: 3052: 3049: 3047: 3044: 3042: 3039: 3037: 3034: 3033: 3031: 3030: 3028: 3026: 3022: 3016: 3013: 3011: 3008: 3006: 3003: 3001: 2998: 2996: 2993: 2991: 2988: 2987: 2985: 2983: 2979: 2976: 2974: 2970: 2967: 2965: 2960: 2956: 2953: 2949: 2945: 2941: 2934: 2929: 2927: 2922: 2920: 2915: 2914: 2911: 2902: 2898: 2894: 2890: 2886: 2882: 2878: 2874: 2869: 2865: 2861: 2857: 2853: 2849: 2845: 2841: 2837: 2831: 2827: 2823: 2819: 2815: 2811: 2807: 2804:(2): 188–90. 2803: 2799: 2794: 2790: 2786: 2782: 2778: 2773: 2768: 2764: 2760: 2756: 2751: 2747: 2743: 2738: 2733: 2729: 2725: 2721: 2716: 2712: 2708: 2703: 2698: 2694: 2690: 2686: 2681: 2677: 2673: 2668: 2663: 2659: 2655: 2651: 2646: 2642: 2638: 2633: 2628: 2625:(6): 849–52. 2624: 2620: 2616: 2611: 2607: 2603: 2598: 2593: 2588: 2583: 2579: 2575: 2572:(8): 3232–7. 2571: 2567: 2563: 2558: 2554: 2550: 2546: 2542: 2537: 2532: 2528: 2524: 2520: 2516: 2511: 2507: 2503: 2498: 2493: 2488: 2483: 2479: 2475: 2471: 2467: 2463: 2458: 2454: 2450: 2446: 2442: 2439:(6): 989–93. 2438: 2434: 2428: 2424: 2420: 2415: 2410: 2405: 2400: 2396: 2392: 2388: 2384: 2380: 2375: 2371: 2367: 2363: 2359: 2356:(4): 988–94. 2355: 2351: 2345: 2341: 2337: 2332: 2327: 2323: 2319: 2316:(3): 909–12. 2315: 2311: 2307: 2302: 2298: 2294: 2289: 2284: 2280: 2276: 2273:(4): 813–21. 2272: 2268: 2264: 2259: 2255: 2251: 2246: 2241: 2238:(8): 1171–8. 2237: 2233: 2229: 2224: 2220: 2216: 2212: 2206: 2202: 2198: 2193: 2188: 2184: 2179: 2178: 2173: 2168: 2164: 2163: 2158: 2154: 2150: 2147: 2143: 2142: 2137: 2133: 2129: 2127: 2124: 2123: 2119: 2110: 2106: 2101: 2096: 2091: 2086: 2082: 2078: 2074: 2067: 2064: 2059: 2053: 2050: 2046: 2041: 2038: 2033: 2029: 2025: 2021: 2017: 2013: 2006: 2004: 2002: 2000: 1996: 1991: 1985: 1982: 1977: 1971: 1968: 1963: 1957: 1954: 1949: 1943: 1940: 1935: 1929: 1926: 1921: 1915: 1912: 1907: 1901: 1898: 1893: 1887: 1884: 1879: 1873: 1870: 1865: 1861: 1857: 1853: 1849: 1845: 1838: 1835: 1830: 1826: 1822: 1818: 1814: 1810: 1806: 1802: 1798: 1794: 1787: 1785: 1781: 1776: 1772: 1767: 1762: 1758: 1754: 1750: 1743: 1740: 1735: 1731: 1725: 1722: 1717: 1713: 1707: 1704: 1700: 1696: 1691: 1689: 1687: 1683: 1679: 1675: 1670: 1668: 1666: 1662: 1655: 1653: 1651: 1647: 1643: 1639: 1635: 1634:grip strength 1631: 1627: 1623: 1622:pelvic girdle 1620:and abnormal 1619: 1615: 1612: 1608: 1604: 1600: 1596: 1586: 1579: 1578: 1571: 1570: 1563: 1562: 1556: 1553: 1552: 1546: 1543: 1542: 1536: 1533: 1532: 1526: 1523: 1520: 1519: 1513: 1510: 1509: 1502: 1501: 1494: 1493: 1487: 1484: 1483: 1477: 1474: 1473: 1467: 1464: 1463: 1457: 1454: 1453: 1447: 1444: 1443: 1437: 1436:Dysmorphology 1434: 1433: 1427: 1424: 1423: 1417:Grip strength 1416: 1415: 1408: 1407: 1401: 1398: 1397: 1390: 1389: 1382: 1381: 1374: 1371: 1370: 1366: 1363: 1362: 1358: 1350: 1348: 1346: 1342: 1334: 1332: 1330: 1327:of the nasal 1326: 1322: 1319:, inner ear, 1318: 1314: 1310: 1305: 1303: 1299: 1295: 1290: 1288: 1284: 1280: 1277: 1273: 1269: 1257: 1252: 1248: 1244: 1241: 1237: 1230: 1228: 1225: 1221: 1217: 1213: 1210: 1206: 1202: 1195: 1193: 1189: 1185: 1181: 1175: 1171: 1168: 1162: 1160: 1156: 1152: 1146: 1142: 1139: 1135: 1128: 1126: 1122: 1118: 1114: 1108: 1104: 1101: 1095: 1093: 1089: 1085: 1081: 1075: 1071: 1068: 1066:RefSeq (mRNA) 1064: 1057: 1056: 1051: 1047: 1044: 1038: 1037: 1032: 1028: 1025: 1023: 1019: 1012: 1011: 1006: 1002: 999: 993: 992: 987: 983: 980: 978: 974: 967: 966: 961: 957: 954: 948: 947: 942: 938: 935: 933: 929: 926: 923: 921: 918: 914: 911: 907: 903: 896: 892: 887: 881: 878: 876: 873: 871: 868: 866: 863: 861: 858: 856: 853: 851: 848: 846: 843: 841: 838: 836: 833: 831: 828: 826: 823: 821: 818: 816: 813: 811: 808: 806: 803: 801: 798: 796: 793: 791: 788: 786: 783: 781: 778: 776: 773: 771: 768: 767: 765: 762: 761: 755: 752: 750: 747: 745: 742: 740: 737: 735: 732: 730: 727: 725: 722: 720: 717: 715: 712: 710: 707: 705: 702: 700: 697: 695: 692: 690: 687: 685: 682: 680: 677: 675: 672: 671: 669: 666: 665: 659: 656: 654: 651: 649: 646: 644: 641: 639: 636: 634: 631: 629: 626: 624: 623:actin binding 621: 619: 616: 614: 611: 609: 606: 604: 601: 599: 596: 594: 591: 589: 586: 584: 581: 580: 578: 575: 574: 571: 570:Gene ontology 567: 563: 551: 546: 543: 541: 537: 529: 524: 513: 509: 505: 501: 497: 494:adrenal gland 493: 489: 485: 481: 477: 476: 473: 469: 464: 461: 451: 447: 443: 439: 435: 431: 427: 423: 419: 415: 414: 411: 407: 402: 399: 398: 395: 393: 389: 387: 386: 382: 381: 378: 376: 372: 368: 364: 360: 352: 347: 343: 339: 334: 324: 320: 313: 306: 300: 293: 285: 281: 277: 272: 268: 263: 259: 251: 246: 242: 238: 233: 223: 219: 212: 205: 199: 192: 188: 182: 178: 174: 169: 165: 160: 156: 152: 148: 144: 140: 136: 132: 128: 124: 120: 116: 108: 103: 96: 91: 86: 75: 73: 67: 62: 59: 58: 54: 51: 44: 40: 35: 31: 27: 22: 19: 5261:Cytoskeleton 5223: 4998:Dystroglycan 4953:Beta catenin 4185:Microtubules 4053:Beta-keratin 3982: 3931: 3877: 3817: 3739: 3725: 3711: 3648: 3485: 3352:Tropomodulin 3206: 2944:cytoskeleton 2879:(3): 268–9. 2876: 2872: 2842:(2): 191–3. 2839: 2835: 2801: 2797: 2762: 2758: 2730:(1): 111–6. 2727: 2723: 2692: 2688: 2660:(3): 440–8. 2657: 2653: 2622: 2618: 2569: 2565: 2521:(3): 375–9. 2518: 2514: 2469: 2465: 2436: 2432: 2386: 2382: 2353: 2349: 2313: 2309: 2270: 2266: 2235: 2231: 2182: 2160: 2139: 2080: 2076: 2066: 2052: 2040: 2015: 2011: 1984: 1970: 1956: 1942: 1928: 1914: 1900: 1886: 1872: 1847: 1843: 1837: 1796: 1792: 1759:(3): 431–9. 1756: 1752: 1742: 1733: 1724: 1715: 1706: 1652:parameters. 1630:pinna reflex 1598: 1593: 1564:Heart weight 1356: 1340: 1338: 1306: 1291: 1275: 1267: 1266: 1188:NP_001243012 1184:NP_001243011 1180:NP_001243010 1177: 1159:NP_001356294 1155:NP_001120652 1148: 1121:NM_001256083 1117:NM_001256082 1113:NM_001256081 1110: 1092:NM_001369365 1088:NM_001127180 1084:NM_001127179 1077: 1053: 1034: 1008: 989: 963: 944: 924: 919: 845:phagocytosis 734:cytoskeleton 694:stereocilium 452:frontal pole 436:right testis 390: 383: 110:External IDs 69: 18: 5144:Plakophilin 5095:Desmoplakin 4855:Tau protein 3629:Cytokeratin 3425:Tropomyosin 2973:Myofilament 2765:(1): 73–9. 1850:(1): 32–8. 1535:Haematology 1486:Radiography 1391:Body weight 1268:Myosin VIIA 714:cell cortex 704:microvillus 633:ATP binding 603:ADP binding 428:left testis 349:97,768,731 336:97,700,267 248:77,215,241 235:77,128,246 88:Identifiers 5240:Categories 5224:See also: 5196:Crescentin 5115:Periplakin 5105:Envoplakin 4993:Dystrophin 4610:axonemal: 4104:Internexin 4083:Peripherin 2536:2066/21703 2083:(6): 224. 1701:, May 2017 1680:, May 2017 1656:References 1611:homozygous 1373:Homozygote 1367:Phenotype 1325:epithelium 1302:organelles 1298:eukaryotic 684:melanosome 394:(ortholog) 131:HomoloGene 4813:Centrin 3 4808:Centrin 2 4803:Centrin 1 4141:Syncoilin 4046:Not alpha 3612:filaments 3564:Fibrillin 2187:CiteSeerX 2018:: 925–7. 1640:, severe 1516:Abnormal 1490:Abnormal 1480:Abnormal 1470:Abnormal 1460:Abnormal 1450:Abnormal 1430:Abnormal 1426:Hot plate 1420:Abnormal 1412:Abnormal 1394:Abnormal 1383:Fertility 1375:viability 1192:NP_032689 1151:NP_000251 1125:NM_008663 1080:NM_000260 910:Orthologs 749:cytoplasm 139:GeneCards 5251:Proteins 5179:Nonhuman 5139:Vinculin 5100:Dystonin 5032:Spectrin 5005:Utrophin 4985:Membrane 4940:Catenins 4872:Stathmin 4860:Dynactin 4740:DYNC2LI1 4735:DYNC1LI2 4730:DYNC1LI1 4395:Kinesins 4199:Tubulins 4088:Vimentin 3620:Type 1/2 3522:Profilin 3517:Gelsolin 3379:Troponin 2940:Proteins 2901:20566524 2864:23555323 2826:13506848 2789:19026117 2759:Genomics 2654:Genomics 2553:22357870 2350:Genomics 2219:15180257 2109:21722353 2032:85911512 1753:Genomics 1697:– 1676:– 1240:Wikidata 889:Sources: 498:yolk sac 5166:PLEKHA7 5120:Plectin 5085:Plakins 5010:Ankyrin 4909:Dynamin 4839:Spastin 4834:Katanin 4798:CAMSAP3 4793:CAMSAP2 4788:CAMSAP1 4760:DYNLRB2 4755:DYNLRB1 4725:DYNC1I2 4720:DYNC1I1 4715:DYNC2H1 4710:DYNC1H1 4603:Dyneins 4327:TUBGCP6 4322:TUBGCP5 4317:TUBGCP4 4312:TUBGCP3 4307:TUBGCP2 4136:Synemin 3879:type II 3741:type II 3624:Keratin 3569:Filamin 3510:Destrin 3493:Cofilin 3454:Actinin 3025:Myosins 2942:of the 2893:9354784 2856:9171833 2818:9171832 2781:9070921 2746:9002678 2711:8900236 2702:1914835 2676:8884267 2641:8776602 2606:8622919 2574:Bibcode 2545:8599365 2506:8022818 2474:Bibcode 2453:7951250 2423:7568224 2391:Bibcode 2370:1478677 2340:9718356 2331:1377414 2297:9382091 2288:1716000 2254:8842737 2167:PDBe-KB 2157:UniProt 2146:PDBe-KB 2136:UniProt 2100:3218837 1864:8160750 1829:4324416 1821:7870171 1801:Bibcode 1775:8884266 1699:Ensembl 1678:Ensembl 1583:Normal 1575:Normal 1567:Normal 1559:Normal 1549:Normal 1539:Normal 1529:Normal 1506:Normal 1498:Normal 1440:Normal 1404:Normal 1400:Anxiety 1386:Normal 1378:Normal 1272:protein 1022:UniProt 977:Ensembl 916:Species 895:QuickGO 795:hearing 744:synapse 674:cytosol 369:pattern 227:11q13.5 95:Aliases 5067:SPTBN5 5062:SPTBN4 5057:SPTBN2 5052:SPTBN1 5042:SPTAN1 4877:Tektin 4770:DYNLT3 4765:DYNLT1 4750:DYNLL2 4745:DYNLL1 4692:DNALI1 4677:DNAH17 4672:DNAH14 4667:DNAH13 4662:DNAH12 4657:DNAH11 4652:DNAH10 4573:KIF26B 4568:KIF26A 4543:KIF21B 4538:KIF21A 4533:KIF20B 4528:KIF20A 4518:KIF18B 4513:KIF18A 4503:KIF16B 4488:KIF13B 4483:KIF13A 4282:TUBB4Q 4267:TUBB2C 4262:TUBB2B 4257:TUBB2A 4237:TUBA4A 4232:TUBA3E 4227:TUBA3D 4222:TUBA3C 4217:TUBA1C 4212:TUBA1B 4207:TUBA1A 4150:Type 5 4109:Nestin 4097:Type 4 4073:Desmin 4066:Type 3 3819:type I 3650:type I 3596:TRIOBP 3262:MYO18B 3257:MYO18A 3253:XVIII 3247:MYO15A 2982:Actins 2899:  2891:  2862:  2854:  2824:  2816:  2787:  2779:  2744:  2709:  2699:  2674:  2639:  2604:  2594:  2551:  2543:  2504:  2494:  2451:  2421:  2411:  2368:  2338:  2328:  2295:  2285:  2252:  2217:  2207:  2189:  2162:P97479 2141:Q13402 2107:  2097:  2030:  1862:  1827:  1819:  1793:Nature 1773:  1626:SHIRPA 1614:mutant 1607:mutant 1522:Plasma 1329:mucosa 1321:retina 1313:kidney 1309:testis 1283:myosin 1226:search 1224:PubMed 1055:P97479 1036:Q13402 932:Entrez 540:BioGPS 444:spleen 127:104510 119:276903 5127:Talin 5110:MACF1 5078:Other 5037:SPTA1 4902:TEKT5 4897:TEKT4 4892:TEKT3 4887:TEKT2 4882:TEKT1 4865:DCTN1 4848:Other 4702:DNAL4 4697:DNAL1 4687:DNAI2 4682:DNAI1 4647:DNAH9 4642:DNAH8 4637:DNAH7 4632:DNAH6 4627:DNAH5 4622:DNAH3 4617:DNAH2 4612:DNAH1 4593:KIFC3 4588:KIFC2 4583:KIFC1 4578:KIF27 4563:KIF25 4558:KIF24 4553:KIF23 4548:KIF22 4523:KIF19 4508:KIF17 4498:KIF15 4493:KIF14 4478:KIF12 4473:KIF11 4453:KIF5C 4448:KIF5B 4443:KIF5A 4438:KIF4B 4433:KIF4A 4428:KIF3C 4423:KIF3B 4418:KIF2C 4413:KIF2A 4408:KIF1B 4403:KIF1A 4375:MAP1B 4370:MAP1A 4337:TUBE1 4332:TUBD1 4302:TUBG2 4297:TUBG1 4292:TUBB8 4287:TUBB6 4277:TUBB4 4272:TUBB3 4252:TUBB1 4242:TUBA8 3591:Espin 3552:Other 3539:Titin 3345:Other 3334:MYLL1 3329:MYLK2 3319:MYLIP 3304:MYL6B 3237:MYO10 3227:MYO9B 3222:MYO9A 3212:MYO7B 3207:MYO7A 3187:MYO5C 3182:MYO5B 3177:MYO5A 3167:MYO3B 3162:MYO3A 3152:MYH16 3147:MYH15 3142:MYH14 3137:MYH13 3132:MYH11 3127:MYH10 3112:MYH7B 3071:MYO1H 3066:MYO1G 3061:MYO1F 3056:MYO1E 3051:MYO1D 3046:MYO1C 3041:MYO1B 3036:MYO1A 2951:Human 2897:S2CID 2860:S2CID 2822:S2CID 2785:S2CID 2597:39588 2549:S2CID 2497:44240 2414:40893 2028:S2CID 1825:S2CID 1599:Myo7a 1357:Myo7a 1341:MYO7A 1287:actin 1276:MYO7A 965:17921 925:Mouse 920:Human 891:Amigo 392:Mouse 385:Human 332:Start 267:Mouse 231:Start 164:Human 143:MYO7A 102:MYO7A 24:MYO7A 5211:ParM 5206:MreB 5201:FtsZ 5161:ACF7 5154:PKP2 5149:PKP1 5132:TLN1 5047:SPTB 5025:ANK3 5020:ANK2 5015:ANK1 4924:DNM3 4919:DNM2 4914:DNM1 4818:PCM1 4468:KIF9 4463:KIF7 4458:KIF6 4385:MAP4 4380:MAP2 4347:MAPs 4247:TUBB 4190:MAPs 4188:and 4129:NEFH 4124:NEFM 4119:NEFL 4078:GFAP 3726:none 3584:FLNC 3579:FLNB 3574:FLNA 3324:MYLK 3314:MYL9 3309:MYL7 3299:MYL6 3294:MYL5 3289:MYL4 3284:MYL3 3279:MYL2 3274:MYL1 3203:VII 3197:MYO6 3158:III 3122:MYH9 3117:MYH8 3107:MYH7 3102:MYH6 3097:MYH4 3092:MYH3 3087:MYH2 3082:MYH1 2964:ABPs 2962:and 2889:PMID 2852:PMID 2814:PMID 2777:PMID 2742:PMID 2707:PMID 2672:PMID 2637:PMID 2602:PMID 2541:PMID 2502:PMID 2449:PMID 2419:PMID 2366:PMID 2336:PMID 2293:PMID 2250:PMID 2215:PMID 2205:ISBN 2155:for 2134:for 2105:PMID 1860:PMID 1817:PMID 1771:PMID 1648:and 1476:DEXA 1317:lung 1279:gene 946:4647 514:iris 375:Bgee 323:Band 284:Chr. 222:Band 181:Chr. 115:OMIM 72:3PVL 53:RCSB 50:PDBe 4975:GAN 4958:APC 4365:EB3 4360:EB2 4355:EB1 4161:A/C 3844:33B 3839:33A 3243:XV 3218:IX 3193:VI 3078:II 2881:doi 2844:doi 2806:doi 2767:doi 2732:doi 2697:PMC 2662:doi 2627:doi 2592:PMC 2582:doi 2531:hdl 2523:doi 2492:PMC 2482:doi 2441:doi 2409:PMC 2399:doi 2358:doi 2326:PMC 2318:doi 2283:PMC 2275:doi 2240:doi 2197:doi 2153:PDB 2132:PDB 2095:PMC 2085:doi 2020:doi 1852:doi 1809:doi 1797:374 1761:doi 1270:is 548:n/a 345:End 244:End 147:OMA 135:219 123:MGI 43:PDB 5242:: 4171:B2 4166:B1 4159:: 4035:80 4030:79 4025:78 4020:77 4015:76 4010:75 4005:74 4000:73 3995:72 3990:71 3974:40 3969:39 3964:28 3959:27 3954:26 3949:25 3944:24 3939:23 3914:86 3909:85 3904:84 3899:83 3894:82 3889:81 3869:38 3864:37 3859:36 3854:35 3849:34 3834:32 3829:31 3786:6C 3781:6B 3776:6A 3756:2A 3731:21 3719:18 3705:20 3700:19 3695:17 3690:16 3685:15 3680:14 3675:13 3670:12 3665:10 3269:LC 3233:X 3173:V 3032:I 3015:G2 3010:G1 3005:C1 2995:A2 2990:A1 2895:. 2887:. 2877:17 2875:. 2858:. 2850:. 2840:16 2838:. 2820:. 2812:. 2802:16 2800:. 2783:. 2775:. 2763:40 2761:. 2757:. 2740:. 2726:. 2722:. 2705:. 2693:59 2691:. 2687:. 2670:. 2658:36 2656:. 2652:. 2635:. 2621:. 2617:. 2600:. 2590:. 2580:. 2570:93 2568:. 2564:. 2547:. 2539:. 2529:. 2519:59 2517:. 2500:. 2490:. 2480:. 2470:91 2468:. 2464:. 2447:. 2435:. 2417:. 2407:. 2397:. 2387:92 2385:. 2381:. 2364:. 2354:14 2352:. 2334:. 2324:. 2314:63 2312:. 2308:. 2291:. 2281:. 2271:61 2269:. 2265:. 2248:. 2234:. 2230:. 2213:. 2203:. 2195:. 2159:: 2138:: 2103:. 2093:. 2081:12 2079:. 2075:. 2026:. 2016:88 2014:. 1998:^ 1858:. 1848:50 1846:. 1823:. 1815:. 1807:. 1795:. 1783:^ 1769:. 1757:36 1755:. 1751:. 1732:. 1714:. 1685:^ 1664:^ 1331:. 1315:, 1311:, 893:/ 351:bp 338:bp 250:bp 237:bp 145:; 141:: 137:; 133:: 129:; 125:: 121:; 117:: 3881:/ 3821:/ 3796:8 3791:7 3771:5 3766:4 3761:3 3751:1 3743:/ 3660:9 3652:/ 3631:) 3626:, 3622:( 3532:2 3527:1 3503:2 3498:1 3474:4 3469:3 3464:2 3459:1 3445:4 3440:3 3435:2 3430:1 3418:3 3415:2 3412:1 3409:I 3404:2 3401:1 3398:C 3393:3 3390:2 3387:1 3384:T 3372:4 3367:3 3362:2 3357:1 3073:) 3000:B 2932:e 2925:t 2918:v 2903:. 2883:: 2866:. 2846:: 2828:. 2808:: 2791:. 2769:: 2748:. 2734:: 2728:6 2713:. 2678:. 2664:: 2643:. 2629:: 2623:5 2608:. 2584:: 2576:: 2555:. 2533:: 2525:: 2508:. 2484:: 2476:: 2455:. 2443:: 2437:3 2425:. 2401:: 2393:: 2372:. 2360:: 2342:. 2320:: 2299:. 2277:: 2256:. 2242:: 2236:5 2221:. 2199:: 2169:. 2148:. 2111:. 2087:: 2060:. 2034:. 2022:: 1866:. 1854:: 1831:. 1811:: 1803:: 1777:. 1763:: 1736:. 1718:. 269:) 166:) 149::

Index

PDB
PDBe
RCSB
3PVL
Aliases
MYO7A
OMIM
276903
MGI
104510
HomoloGene
219
GeneCards
MYO7A
OMA
MYO7A - orthologs
Human
Chromosome 11 (human)
Chr.
Chromosome 11 (human)
Chromosome 11 (human)
Genomic location for MYO7A
Genomic location for MYO7A
Band
bp
bp
Mouse
Chromosome 7 (mouse)
Chr.
Chromosome 7 (mouse)

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