192:. In cystic fibrosis, the meconium can form a bituminous black-green mechanical obstruction in a segment of the ileum. Beyond this, there may be a few separate grey-white globular pellets. Below this level, the bowel is a narrow and empty micro-colon. Above the level of the obstruction, there are several loops of hypertrophied bowel distended with fluid. No meconium is passed, and abdominal distension and vomiting appear soon after birth. About 20% of cases of cystic fibrosis present with meconium ileus, while approximately 20% of one series of cases of meconium ileus did not have cystic fibrosis. The presence of meconium ileus is not related to the severity of the cystic fibrosis. The obstruction can be relieved in a number of ways.
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124:, and water. Meconium, unlike later feces, is viscous and sticky like tar – its color usually being a very dark olive green and it is almost odorless. When diluted in amniotic fluid, it may appear in various shades of green, brown, or yellow. It should be completely passed by the end of the first few days after birth, with the stools progressing toward yellow (digested milk).
333:
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contamination after sample collection and that meconium is, in fact, sterile until after birth. Further researchers have hypothesized that there may be bacteria in the womb, but these are a normal part of pregnancy and could have an important role in shaping the developing immune system and are not harmful to the baby.
195:
Meconium ileus should be distinguished from meconium plug syndrome, in which a tenacious mass of mucus prevents the meconium from passing and there is no risk of intestinal perforation. Meconium ileus has a significant risk of intestinal perforation. In a barium enema, meconium plug syndrome shows a
153:(when they are more than 40 weeks pregnant) may also have meconium-stained amniotic fluid without fetal distress. Medical staff may aspirate the meconium from the nose and mouth of a newborn immediately after delivery in the event the baby shows signs of respiratory distress to decrease the risk of
160:
Most of the time that the amniotic fluid is stained with meconium, it will be homogeneously distributed throughout the fluid, making it brown. This indicates that the fetus passed the meconium some time ago such that sufficient mixing occurred as to establish the homogeneous mixture. Terminal
231:
The issue of whether meconium is sterile remains debated and is an area of ongoing research. Although some researchers have reported evidence of bacteria in meconium, this has not been consistently confirmed. Other researchers have raised questions about whether these findings may be due to
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if the capacity of the parents to look after their child is in question. Meconium can also be analyzed to detect the tobacco use of mothers during their pregnancy, which is commonly under-reported.
161:
meconium occurs when the fetus passes the meconium a short enough time before birth/cesarean section that the amniotic fluid remains clear, but individual clumps of meconium are in the fluid.
528:"A prospective cohort study of biomarkers of prenatal tobacco smoke exposure: the correlation between serum and meconium and their association with infant birth weight"
362:
This image compares the appearance of meconium (from 48 hours after normal delivery at term) to the appearance of the same infant's feces after 1 week of breastfeeding.
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643:"A critical assessment of the 'sterile womb' and 'in utero colonization' hypotheses: implications for research on the pioneer infant microbiome"
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212:, fatty acid ethyl esters (FAEE), they could objectively detect excessive maternal alcohol consumption during pregnancy.
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Placental handling of fatty acid ethyl esters: perfusion and subcellular studies. J Pharmacol ExpTher 2004; 310: 75-82.
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Meconium is normally retained in the infant's bowel until after birth, but sometimes it is expelled into the
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waste product from the pupal stage of an insect that is expelled through the anal opening of the adult upon
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220:
100:. Unlike later feces, meconium is composed of materials ingested during the time the infant spends in the
600:
JimĂ©nez E, MarĂn ML, MartĂn R, Odriozola JM, Olivares M, Xaus J, Fernández L, RodrĂguez JM (April 2008).
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exposure. Using meconium, a
Canadian research group showed that by measuring a by-product of
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Braun JM, Daniels JL, Poole C, Olshan AF, Hornung R, Bernert JT, et al. (August 2010).
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145:. The stained amniotic fluid is recognized by medical staff as a possible sign of
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The failure to pass meconium is a symptom of several diseases including
316:) expel the meconium at the end of the larval stage, before becoming a
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normal or dilated colon as compared to micro-colon in meconium ileus.
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Perez-Muñoz ME, Arrieta MC, Ramer-Tait AE, Walter J (April 2017).
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The meconium sometimes becomes thickened and congested in the
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In the US, the results of meconium testing may be used by
476:"Surgical Aspects of Cystic Fibrosis and Meconium Ileus"
204:
Meconium can be tested for various drugs, to check for
581:"Baby's first full diaper can reveal mother's smoking"
157:, which can occur in meconium-stained amniotic fluid.
694:"Could baby's first bacteria take root before birth?"
602:"Is meconium from healthy newborns actually sterile?"
852:
532:
Environmental Health: A Global Access
Science Source
856:
514:
G.B. v. Dearborn County Div. of Family and
Children
453:(2nd ed.). Oxford: Blackwell. pp. 74–75.
71:
42:
402:
283:'s belief that it induces sleep in the fetus.
474:Irish M (29 December 2015). Minkes RK (ed.).
8:
409:(4th ed.). London: Lloyd-Luke. p.
188:. Meconium ileus is often the first sign of
30:For the historical meaning of the term, see
743:"HON Mother & Child Glossary, Meconium"
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384:(Maryland Heights MO: Mosby, 1991), 82.
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516:, 754 N.E.2d 1027 (Ind.Ct.App., 2001).
7:
27:Earliest feces of a mammalian infant
292:In biology, meconium describes the
61: – the baby's third
482:from the original on 30 April 2003
350:Meconium from 13-hour-old newborn.
25:
587:(Press release). August 27, 2010.
840:
355:
343:
331:
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819:from the original on 2017-08-21
1:
405:Practical Paediatric Problems
619:10.1016/j.resmic.2007.12.007
500:Chan D, Knie B, Boskovic R,
338:Newborn evacuating meconium.
155:meconium aspiration syndrome
812:Online Etymology Dictionary
692:Willyard C (January 2018).
451:Clinical Paediatric Surgery
924:
773:
719:10.1038/d41586-018-00664-8
263:
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200:Testing meconium for drugs
133:Meconium in amniotic fluid
67:Scale: 5 cm left to right.
57:Meconium from 12-hour-old
29:
660:10.1186/s40168-017-0268-4
304:. Other insects, such as
217:child protective services
141:prior to birth or during
56:
47:
606:Research in Microbiology
221:law enforcement agencies
165:Failure to pass meconium
789:A Greek–English Lexicon
382:Basic Pediatric Nursing
184:, a condition known as
553:10.1186/1476-069X-9-53
401:Hutchinson JH (1975).
380:Persis Mary Hamilton,
171:Hirschsprung's disease
151:post-dates pregnancies
780:Liddell, Henry George
128:Clinical significance
849:at Wikimedia Commons
710:2018Natur.553..264W
544:2010EnvHe...9...53B
279:preparations or to
261:, a diminutive of
143:labor and delivery
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884:
845:Media related to
741:O'Dochartaigh S.
704:(7688): 264–266.
449:Jones PG (1976).
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37:Medical condition
16:(Redirected from
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175:cystic fibrosis
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434:Hekmatnia A.
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908:Neonatology
310:Hymenoptera
892:Categories
823:2013-11-06
807:"meconium"
747:www.hon.ch
647:Microbiome
486:25 October
368:References
287:Other uses
219:and other
182:intestines
98:defecation
78:Pediatrics
653:(1): 48.
538:(1): 53.
308:and some
300:from the
294:metabolic
281:Aristotle
236:Etymology
227:Sterility
73:Specialty
847:Meconium
817:Archived
774:μηκώνιον
757:17 April
728:29345664
679:28454555
628:18281199
572:20799929
502:Koren G.
480:Archived
314:Aculeata
298:eclosion
259:mēkōnion
254:μηκώνιον
246:meconium
206:in utero
86:Meconium
43:Meconium
876:D008470
792:at the
706:Bibcode
670:5410102
563:2944243
540:Bibcode
325:Gallery
306:beetles
210:alcohol
149:. Some
59:newborn
726:
698:Nature
677:
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570:
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388:
110:lanugo
102:uterus
94:infant
898:Feces
277:opium
273:poppy
269:mēkōn
264:μήκων
250:Greek
244:term
242:Latin
114:mucus
90:stool
32:Opium
871:MeSH
759:2018
724:PMID
675:PMID
624:PMID
568:PMID
488:2007
455:ISBN
415:ISBN
386:ISBN
318:pupa
302:pupa
240:The
173:and
122:bile
714:doi
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655:doi
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558:PMC
548:doi
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