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This nucleus is also presumed to play a role in monitoring internal movements of the eye. Specifically, its function is to relay the information about how the eyes will be moved (efference copy, also known as corollary discharge) from the superior colliculus to the frontal eye fields (FEF) in order
330:
While both the ventral and medial dorsal nuclei process pain, the medial dorsal nucleus bypasses primary cortices, sending their axons directly to secondary and association cortices. The cells also send axons directly to many parts of the brain, including nuclei of the limbic system such as the
335:
is less accurate, and less detailed in regards to sensory signal analysis. This processing is known colloquially as "fast and dirty" rather than the "slow and accurate" system of classical or lemniscal system. This pathway activates parts of the brain that evoke emotional responses.
263:, therefore involved in prefrontal functions. Damage to the interconnected tract or the nucleus itself will result in similar damage to the prefrontal cortex. It is also believed to play a role in
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lateral nucleus of the amygdala, the anterior cingulate, and the hippocampus. This part of the sensory system, known as the non-classical or
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484:
Li XB, Inoue T, Nakagawa S, Koyama T (May 2004). "Effect of mediodorsal thalamic nucleus lesion on contextual fear conditioning in rats".
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291:. As a result, it plays a crucial role in attention, planning, organization, abstract thinking, multi-tasking, and active memory.
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535:(2006). "The prefrontal cortex in the Göttingen minipig brain defined by neural projection criteria and cytoarchitecture".
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to aid the neurons in FEF to change their receptive fields to where the visual stimuli will appear after the saccade.
686:"What does a comparison of the alcoholic Korsakoff syndrome and thalamic infarction tell us about thalamic amnesia?"
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The connections of the medial dorsal nucleus have even been used to delineate the prefrontal cortex of the
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586:"Excess of Neurons in the Human Newborn Mediodorsal Thalamus Compared with That of the Adult"
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Maja Abitz; Rune
Damgaard Nielsen; Edward G. Jones; Henning Laursen; Niels Graem &
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Stained brain slice images which include the "Mediodorsal nucleus"
410:
Nolte's The human brain: an introduction to its functional anatomy
130:
734:
Aage R. Moller "Pain: Its anatomy, physiology and treatment" 2012
757:
412:(7th ed.). Philadelphia, PA: Elsevier. pp. 408–409.
353:
Damage to the medial dorsal nucleus has been associated with
408:
Vanderah, Todd W.; Gould, Douglas J.; Nolte, John (2016).
629:"Brain circuits for the internal monitoring of movements"
309:
in the region has been estimated at around 6.43 million
252:. It is separated from the other thalamic nuclei by the
259:
The medial dorsal nucleus is interconnected with the
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527:Jacob Jelsing; Anders Hay-Schmidt; Tim Dyrby;
283:and projects to the prefrontal cortex and the
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114:Thalamic nuclei (right thalamus from above)
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627:Sommer, Marc A.; Wurtz, Robert H. (2008).
313:in the adult human brain and 36.3 million
287:and in turn relays them to the prefrontal
108:
40:Thalamic nuclei: (left thalamus from left)
34:
1215:Posterior (sympathetic/heat conservation)
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693:Neuroscience & Biobehavioral Reviews
435:"What does the mediodorsal thalamus do?"
397:
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645:10.1146/annurev.neuro.31.060407.125627
219:
25:
7:
1210:Anterior (parasympathetic/heat loss)
403:
401:
684:Kopelman, Michael D. (2015-07-01).
433:Mitchell AS, Chakraborty S (2013).
551:10.1016/j.brainresbull.2006.06.009
14:
1249:Parvocellular neurosecretory cell
1244:Magnocellular neurosecretory cell
1132:Anterior trigeminothalamic tract
379:
367:
216:Anatomical terms of neuroanatomy
21:Dorsomedial hypothalamic nucleus
706:10.1016/j.neubiorev.2014.08.014
238:mediodorsal nucleus of thalamus
1369:Dorsal longitudinal fasciculus
498:10.1016/j.brainres.2004.02.038
71:Ventral posterolateral nucleus
1:
633:Annual Review of Neuroscience
136:nucleus mediodorsalis thalami
76:Ventral posteromedial nucleus
16:Large nucleus in the thalamus
885:Stria medullaris of thalamus
1287:Suprachiasmatic (melatonin)
1468:
890:Thalamic reticular nucleus
695:. The Cognitive Thalamus.
275:It relays inputs from the
96:Lateral geniculate nucleus
52:MD = Medial dorsal nucleus
18:
254:internal medullary lamina
214:
107:
101:Medial geniculate nucleus
33:
1426:Nuclei campi perizonalis
1352:Retinohypothalamic tract
452:10.3389/fnsys.2013.00037
61:Ventral anterior nucleus
19:Not to be confused with
1347:Medial forebrain bundle
1277:Arcuate (dopamine/GHRH)
538:Brain Research Bulletin
531:; Harry B. M. Uylings;
340:Saccadic efference copy
66:Ventral lateral nucleus
1364:Mammillothalamic tract
1127:Subthalamic fasciculus
1061:Pallidothalamic tracts
1056:Mammillothalamic tract
1038:Interthalamic adhesion
49:Anterior nuclear group
1391:is diencephalon, but
1112:Dentatothalamic tract
1071:Lenticular fasciculus
1033:Midline nuclear group
605:10.1093/cercor/bhl163
349:Clinical significance
333:extralemniscal system
242:dorsal medial nucleus
234:medial dorsal nucleus
81:Lateral nuclear group
56:Ventral nuclear group
44:Midline nuclear group
29:Medial dorsal nucleus
1095:Trigeminal lemniscus
856:Subcommissural organ
828:Habenular commissure
355:Korsakoff's syndrome
1416:Subthalamic nucleus
1234:posterior pituitary
1102:Spinothalamic tract
1076:Thalamic fasciculus
439:Front Syst Neurosci
1117:Acoustic radiation
289:association cortex
1439:
1438:
1402:
1401:
1323:
1322:
1147:
1146:
1139:Medullary laminae
1107:Lateral lemniscus
1066:Ansa lenticularis
864:
863:
823:Habenular trigone
749:BrainMaps project
598:(11): 2573–2578.
419:978-1-4557-2859-6
361:Additional images
296:Göttingen minipig
261:prefrontal cortex
230:
229:
225:
1459:
1342:Stria terminalis
1197:
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1090:Medial lemniscus
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851:Habenular nuclei
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545:(4–6): 322–336.
533:Bente Pakkenberg
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281:olfactory cortex
222:edit on Wikidata
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1452:Thalamic nuclei
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1430:Fields of Forel
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1282:Preoptic (GnRH)
1239:Paraventricular
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1177:Mammillary body
1168:Median eminence
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1122:Optic radiation
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970:Pulvinar nuclei
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784:Anatomy of the
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1421:Zona incerta
1395:is glandular
1358:
1336:
1329:White matter
1310:Ventromedial
1273:
1232:
1182:Infundibulum
1153:Hypothalamus
1082:
1048:White matter
1026:Centromedian
1021:Intralaminar
1015:
1012:
977:Metathalamus
917:
813:Pineal gland
786:diencephalon
696:
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185:A14.1.08.622
173:birnlex_1543
135:
91:Metathalamus
1408:Subthalamus
1315:Dorsomedial
1265:vasopressin
1192:Grey matter
905:Grey matter
838:Grey matter
798:Epithalamus
790:human brain
639:: 317–338.
315:glial cells
307:brain cells
125:Identifiers
1256:Supraoptic
392:References
303:stereology
155:NeuroNames
1389:Posterior
1381:Pituitary
1225:Endocrine
1201:Autonomic
715:0149-7634
699:: 46–56.
653:0147-006X
486:Brain Res
271:Structure
1446:Category
1393:anterior
1359:efferent
1337:afferent
1261:oxytocin
1013:midline:
870:Thalamus
818:Habenula
723:25218758
671:18558858
614:17218480
584:(2007).
567:38174266
559:17027768
514:36284389
506:15145764
471:23950738
386:Thalamus
374:Thalamus
321:Function
277:amygdala
250:thalamus
167:NeuroLex
86:Pulvinar
1305:Lateral
1297:Emotion
1161:Surface
955:Lateral
926:Ventral
918:paired:
878:Surface
806:Surface
788:of the
747:at the
662:2813694
462:3738868
311:neurons
298:brain.
248:in the
246:nucleus
148:D020645
120:Details
1274:other:
1002:K cell
997:M cell
992:P cell
910:nuclei
721:
713:
669:
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651:
612:
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557:
512:
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469:
459:
445:: 37.
416:
265:memory
89:MTh =
84:PUL =
79:LNG =
74:VPM =
69:VPL =
54:VNG =
42:MNG =
1203:zones
689:(PDF)
563:S2CID
510:S2CID
240:, or
220:[
209:62156
131:Latin
99:MG =
94:LG =
64:VL =
59:VA =
47:AN =
1084:PCML
719:PMID
711:ISSN
667:PMID
649:ISSN
610:PMID
555:PMID
502:PMID
490:1008
467:PMID
414:ISBN
279:and
236:(or
232:The
197:5681
180:TA98
143:MeSH
948:VPL
944:VPM
701:doi
657:PMC
641:doi
600:doi
547:doi
494:doi
457:PMC
447:doi
301:By
204:FMA
192:TA2
160:312
1448::
1016:MD
987:LG
982:MG
965:LP
960:LD
940:VP
935:VL
931:VA
921:AN
717:.
709:.
697:54
691:.
665:.
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637:31
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608:.
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543:70
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508:.
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465:.
455:.
441:.
437:.
400:^
357:.
267:.
256:.
169:ID
1432:)
1428:(
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1236::
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933:/
907:/
777:e
770:t
763:v
725:.
703::
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643::
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23:.
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