115:
111:(professor of medicinal chemistry, University of Bath) in the field of steroid hormones. It resulted the development of inhibitors for several steroidogenic enzyme targets. One of these completed a Phase 1 trial in women with advanced breast cancer, in collaboration with Charles Coombes and CRUK. Sterix was acquired by Ipsen in 2004.
139:
A commemorative symposium was held on 6 April 2010 in
Edinburgh to celebrate his scientific achievements. The symposium focused on the main area of Reed's research – the production and role of female sex hormones in women with hormone-dependent cancers.
127:
Reed won the 2009 GlaxoSmithKline (GSK) International
Achievement Award, jointly with Barry Potter. He also won The Royal Society of Chemistry BMCS Malcolm Campbell Memorial Award 2009, jointly with L.W.L. Woo and B.V.L. Potter from
102:
inhibitors for the control of steroid-responsive cancers. These studies attracted commercial funding and the creation of an
Imperial Start-up – Sterix Ltd, formed in 1998 as a spin-off from Imperial College, London and the
276:
377:
372:
367:
20:
362:
69:
95:
98:, Reed's research became more directed towards developing therapies. Together with A. Purohit, he developed a research programme in
57:
297:
79:
Reed was appointed lecturer at St. Mary's in 1978, senior lecturer in 1983 and reader in 1992. His principal work was on
319:
347:
91:. In 1995 he was appointed professor of steroid biochemistry in the Department of Endocrinology and Metabolic Medicine.
76:
in the
Department of Chemical Pathology. He then focused his attention to the regulation of aromatase in breast cancer.
24:(30 May 1944 – 6 April 2009) was a British chemist who held the position of professor of steroid biochemistry at
25:
73:
251:
114:
357:
352:
41:
53:
178:
104:
65:
48:
from
Imperial College in 1969. He then commenced research into the actions and metabolism of
99:
49:
320:"Reporter-Sharing stories of Imperial's community. Symposium honouring Mike Reed – Reporter"
170:
108:
203:
83:
methods, using radioactive substrate infusions to calculate the extent of aromatisation in
84:
341:
158:
88:
182:
45:
252:"Ipsen Acquires Sterix Limited and Reinforces its Pipeline in Oncology – Evaluate"
215:
60:, London, culminating in a PhD in 1973. He continued to work on the regulation of
174:
61:
37:
277:"Discovery of steroid sulphatase inhibitors recognised with GSK award"
159:"Professor Michael John Reed, BSc, MSc, PhD, DSc, FRCPath (1944–2009)"
237:
113:
204:
http://www.endocrinology.org/endocrinologist/092/092.pdf
129:
133:
157:
Purohit, Alan (Atul; Potter, Barry (1 November 2009).
163:
Journal of
Steroid Biochemistry and Molecular Biology
8:
378:Fellows of the Royal College of Pathologists
149:
7:
373:Academics of Imperial College London
96:Imperial College School of Medicine
368:Alumni of the University of London
14:
363:Alumni of Imperial College London
107:, based on the work of Reed and
70:St Mary's Hospital Medical School
58:Royal Postgraduate Medical School
1:
322:. imperial.ac.uk. 20 May 2010
298:"BMCS Malcolm Campbell Award"
175:10.1016/j.jsbmb.2009.07.008
394:
94:After the creation of the
192:– via ResearchGate.
17:Professor Michael J. Reed
216:"Home – Dr Atul Purohit"
118:Professor Michael J Reed
36:Reed obtained a BSc in
26:Imperial College, London
130:The University of Bath
119:
44:in 1967 and an MSc in
256:www.evaluategroup.com
117:
238:"Cancer Research UK"
132:and A. Purohit from
42:University of London
348:British biochemists
123:Awards and honours
120:
105:University of Bath
100:steroid sulphatase
66:endometrial cancer
72:in 1976, to join
68:before moving to
50:ethinyloestradiol
32:Scientific career
385:
332:
331:
329:
327:
316:
310:
309:
307:
305:
294:
288:
287:
285:
283:
273:
267:
266:
264:
262:
248:
242:
241:
234:
228:
227:
225:
223:
212:
206:
200:
194:
193:
191:
189:
169:(4–5): 185–186.
154:
134:Imperial College
109:Barry V L Potter
23:
393:
392:
388:
387:
386:
384:
383:
382:
338:
337:
336:
335:
325:
323:
318:
317:
313:
303:
301:
296:
295:
291:
281:
279:
275:
274:
270:
260:
258:
250:
249:
245:
236:
235:
231:
221:
219:
214:
213:
209:
201:
197:
187:
185:
156:
155:
151:
146:
125:
34:
19:
12:
11:
5:
391:
389:
381:
380:
375:
370:
365:
360:
355:
350:
340:
339:
334:
333:
311:
289:
268:
243:
229:
207:
195:
148:
147:
145:
142:
124:
121:
85:postmenopausal
33:
30:
13:
10:
9:
6:
4:
3:
2:
390:
379:
376:
374:
371:
369:
366:
364:
361:
359:
356:
354:
351:
349:
346:
345:
343:
321:
315:
312:
299:
293:
290:
278:
272:
269:
257:
253:
247:
244:
239:
233:
230:
217:
211:
208:
205:
199:
196:
184:
180:
176:
172:
168:
164:
160:
153:
150:
143:
141:
137:
135:
131:
122:
116:
112:
110:
106:
101:
97:
92:
90:
89:breast cancer
86:
82:
77:
75:
71:
67:
64:synthesis in
63:
59:
55:
51:
47:
43:
39:
31:
29:
27:
22:
18:
324:. Retrieved
314:
302:. Retrieved
292:
280:. Retrieved
271:
259:. Retrieved
255:
246:
232:
220:. Retrieved
210:
198:
186:. Retrieved
166:
162:
152:
138:
126:
93:
80:
78:
74:Vivian James
54:Ken Fotherby
46:biochemistry
35:
16:
15:
358:2009 deaths
353:1944 births
218:. .ic.ac.uk
202:Page 11 in
87:women with
342:Categories
144:References
300:. Rsc.org
62:oestrogen
40:from the
183:54230909
326:6 April
304:6 April
282:6 April
261:6 April
222:6 April
188:6 April
81:in vivo
56:at the
38:zoology
21:FRCPath
181:
179:S2CID
52:with
328:2018
306:2018
284:2018
263:2018
224:2018
190:2018
171:doi
167:117
344::
254:.
177:.
165:.
161:.
136:.
28:.
330:.
308:.
286:.
265:.
240:.
226:.
173::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
