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Michael Jeffrey Aminoff

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applications of electrodiagnostic techniques or at providing insight into the underlying pathophysiology of various disorders. His work on different aspects of the autonomic nervous system showed involvement of sympathetic fibers in entrapment neuropathies; the importance of spinal mechanisms in the control of breathing; the nature and consequences of the dysautonomia occurring in patients with Parkinson's disease; and the nature of the involuntary motor activity that follows cessation of the cerebral circulation (syncope). His studies of the physiology of sensory discrimination and motor control showed that the discrimination-response system is organized as a parallel network rather than in the serial manner often portrayed, and he provided evidence that the long-latency stretch responses have a transcerebral pathway in humans, are under some degree of voluntary control, and relate to the organization of the discrimination-response system. His studies provided electrophysiological evidence for different types of dementia and defined their electrophysiological characteristics.
90: 370:(London) on the spinal integration of various inputs to respiratory motor neurons. He subsequently moved to the University of California San Francisco, where he has held various faculty positions in the department of neurology, becoming a full professor in 1982, and was awarded the title of distinguished professor in 2010. He retired in 2022, becoming distinguished professor emeritus. He was certified in neurology by the 374:(ABPN) in 1982 (recertified, 2004) and received subspecialty certification in clinical neurophysiology by the ABPN when this new subspecialty was created in 1992 (recertified 2002). In 2000 the University of London awarded him a doctorate in science (a higher doctorate in the faculty of science) for his electrophysiological studies of the nervous system in health and disease. 25: 387:
cord ischemia. This is now widely accepted and has had major implications for the treatment of these lesions. His later interest in movement disorders led him to show the utility of botulinum toxin in the treatment of various movement disorders, and then to study gene therapy in managing patients with Parkinson's disease.
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guidelines and educational standards, and assessing competence in clinical neurophysiology and clinical neurology. He lectured frequently at regional, national and international meetings, authored or edited numerous books on neurological science and education, and in 2003 was appointed one of the series editors of the
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Aminoff's clinical studies of spinal vascular malformations (dural arteriovenous fistulas) led to a new theory on their pathophysiology. He and his collaborators suggested that increased venous pressure reduces the intramedullary arteriovenous pressure gradient and thus blood flow, leading to spinal
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Valles, F; Fiandaca, MS; Eberling, JL; Starr, PA; Larson, PS; Christine, CW; Forsayeth, J; Richardson, RM; Su, X; Aminoff, MJ; Bankiewicz, KS (2010). "Qualitative imaging of adeno-associated virus serotype 2-human aromatic L-amino acid decarboxylase gene therapy in a phase I study for the treatment
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in 2006, and the 2007 A.B. Baker Award of the American Academy of Neurology for lifetime achievements and contributions to medical education. From 2004 to 2012 he was a director of the American Board of Psychiatry and Neurology, serving as chair of the board in 2011 and in 2010 UCSF awarded him the
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Aminoff has devoted many years to medical education. As a director and chair of the American Board of Clinical Neurophysiology, of the American Board of Electrodiagnostic Medicine, and of the American Board of Psychiatry & Neurology, he was concerned with syllabus development, setting national
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He has authored many medical and scientific papers, particularly on electrophysiological studies of the nervous system in health and disease. His scientific published works earned him a Doctorate in Science, an advanced doctorate in the Faculty of Science from the University of London, in 2000. He
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Aminoff is a clinical neurologist and neurophysiologist whose original contributions have been in several overlapping areas, utilizing electrophysiological techniques to investigate the functioning of the nervous system in health and disease. His work has been directed at extending the clinical
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Aminoff received a Bachelor of Science degree from University College London (1962) and his medical degree (M.B., B.S.) from University College Hospital (UCH) Medical School (London) in 1965. After internship at UCH, he trained in internal medicine at various London teaching hospitals, gained
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has written or edited 40 books, including several comprehensive textbooks that have gone into numerous editions. His published works have been translated into 8 languages. He was editor-in-chief of the neuroscience journal
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Aminoff is a clinical neurologist and neurophysiologist, clinical investigator, university professor, author, and editor with a special interest in medical history. He was born and educated in England, graduating from
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Goodin, DS; Aminoff, MJ; Shefrin, SL (1990). "The organization of sensory discrimination and response selection in choice and nonchoice conditions: a study using cerebral evoked potentials in normal humans".
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Second Edition, 1993; Third edition, 1996; Fourth Edition, 1999; Fifth Edition, 2002; Sixth Edition, 2005; Seventh Edition, 2009; Eighth Edition, 2012; Ninth Edition, 2015; Tenth Edition, 2018, 11th Edition
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in 1965. He subsequently trained in neurology and neurophysiology at The National Hospital (Queen Square) in London, and moved to San Francisco in 1976 where he became Professor of Neurology in 1982 at the
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Harrison's Neurology in Clinical Medicine, Chapter 6: Electrodiagnostic Studies of Nervous System Disorders: EEG, Evoked Potentials, and EMG; Author: Michael J. Aminoff. Eds: Stephen L. Hauser, S. Andrew
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Program on Parkinson's disease for health-care professionals produced by UCTV and aired nationally for 1 week in 2011. Continues to be available on websites for UCTV, YouTube, and the UCSF PD Center.
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Program on Parkinson's disease for patients and caregivers produced by UCTV and aired nationally for 1 week in 2011. Continues to be available on websites for UCTV, YouTube, and the UCSF PD Center.
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Eberling, JL; Jagust, WJ; Christine, CW; Starr, P; Larson, P; Bankiewicz, KS; Aminoff, MJ (2009). "Results from a phase I safety trial of hAADC gene therapy for Parkinson's disease".
286:. He was Director of UCSF's Clinical Neurophysiology Laboratories until 2004. Aminoff directed UCSF's Parkinson's Disease Clinic and Research Center, a National Parkinson Foundation 1908: 1923: 675:"Michael J Aminoff, UCSF, Distinguished Professor of Neurology; Director, Parkinson's Disease Clinic & Research Center; Executive Vice Chair, Department of Neurology" 1685: 366:(Queen Square and Maida Vale) in London. He received his M.D. degree, which in England is awarded for an advanced research thesis, for his experimental studies at the 1229:
Goodin, DS; Aminoff, MJ; Shih, PY (1990). "Evidence that the long-latency stretch responses of the human wrist extensor muscle involve a transcerebral pathway".
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Aminoff, MJ; Scheinman, MM; Griffin, JC; Herre, JM (1988). "Electrocerebral accompaniments of syncope associated with malignant ventricular arrhythmias".
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of London (equivalent to obtaining certification in internal medicine in the U.S.) and then trained in neurology and clinical neurophysiology at the
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Robert S. Schwab Award for outstanding contributions to research in peripheral clinical neurophysiology, American Clinical Neurophysiology Society.
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Lifetime Achievement Award, American Association of Neuromuscular and Electrodiagnostic Medicine; A.B. Baker Award], American Academy of Neurology
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Aminoff has received numerous honors and awards for his work as an educator and neurologist, including the Lifetime Achievement Award from the
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Michael J. Aminoff Annual Neurology Lectureship established within the Division of Neurology at Miami Neuroscience Institute, South Florida.
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Gelb, DJ; Lowenstein, DH; Aminoff, MJ (1989). "Controlled trial of botulinum toxin injections in the treatment of spasmodic torticollis".
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Forsayeth, J; Bankiewicz, KS; Aminoff, MJ (2010). "Gene therapy for Parkinson's disease: where are we now and where are we going?".
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Christine CW, Starr PA, Larson PS, Eberling JL, Jagust WJ, Hawkins RA, VanBrocklin HF, Wright JF, Bankiewicz KS, Aminoff MJ (2009).
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First Edition, 1980; Second Edition, 1986; Third Edition, 1992; Fourth Edition, 1999; Fifth Edition, 2005; Sixth Edition, 2012 (as
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An endowed chair in Parkinson's Disease Research is being established in his name at the University of California San Francisco.
620:. (In two volumes or parts). Elsevier Saunders, Philadelphia, 2013; 3rd Edition edited by Aminoff MJ, Pomeroy SL, Levin KH, 2024 1093:
Aminoff MJ, Sears TA: "Spinal integration of segmental, cortical and breathing inputs to thoracic respiratory motoneurons.
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Yoshimura, DM; Aminoff, MJ; Tami, TA; Scott, AB (1992). "Treatment of hemifacial spasm with botulinum toxin".
744: 345:. With Larry R. Faulkner he edited a volume on the history of the American Board of Psychiatry and Neurology. 972: 761: 537:
Second Edition, 1995; Third Edition, 2001; Fourth Edition, 2008; Fifth Edition, 2014 (with Josephson SA; as
1893: 367: 257: 1679: 987:"Subspecialty Certification in Clinical Neurophysiology, The American Board of Psychiatry and Neurology" 730: 1918: 925:"Spinal integration of segmental, cortical and breathing inputs to thoracic respiratory motoneurones" 287: 703:"Michael J. Aminoff, MD, DSc, FRCP, Director of UCSF Parkinson's Disease Clinic and Research Center" 1390:
Aminoff, MJ; Barnard, RO; Logue, V (1974). "The pathophysiology of spinal vascular malformations".
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Aminoff has a longstanding interest in the history of medicine and is the author of biographies of
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Goodin, DS; Aminoff, MJ (1986). "Electrophysiological differences between subtypes of dementia".
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Lifetime Achievement Award, American Association of Neuromuscular and Electrodiagnostic Medicine
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Yoshimura, DM; Aminoff, MJ; Olney, RK (1992). "Botulinum toxin therapy for limb dystonias".
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Aminoff, MJ (1980). "Peripheral sympathetic function in patients with a polyneuropathy".
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The Netter Collection of Medical Illustrations, 2nd Edition. Volume 7: The Nervous System
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Electromyography in Clinical Practice. Electrodiagnostic Aspects of Neuromuscular Disease
776:"Electrodiagnostic Studies of Nervous System Disorders: Eeg, Evoked Potentials, and Emg" 89: 1828: 1786: 1662: 1637: 1613: 1135: 1108: 949: 924: 342: 1028: 1001: 443:
Endowed Chair in Parkinson's Disease Research, University of California, San Francisco
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Awarded title of “Distinguished Professor” at University of California, San Francisco
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Aminoff, MJ; Logue, V (1974). "Clinical features of spinal vascular malformations".
1080: 1002:"Involvement of peripheral vasomotor fibres in patients with carpal tunnel syndrome" 905: 837: 794: 458:             1846: 940: 183:
Professor of Neurology, School of Medicine, University of California, San Francisco
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Honorary member, Gold-Headed Cane Society, University of California, San Francisco
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Neuromuscular Function and Disease: Basic, Clinical and Electrodiagnostic Aspects
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Sir Charles Bell: His Life, Art, Neurological Concepts, and Controversial Legacy
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Sir Charles Bell: His Life, Art, Neurological Concepts, and Controversial Legacy
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Queen Square Prize for Research in Neurology, Institute of Neurology, London, UK
249: 1277: 1242: 973:"UCSF Department of Neurology, Endowed Chairs and Distinguished Professorships" 762:"UCSF Department of Neurology, Endowed Chairs and Distinguished Professorships" 1804: 1638:"Safety and tolerability of putaminal AADC gene therapy for Parkinson disease" 1207: 1367: 1350: 1327: 908:
The American Board of Psychiatry and Neurology: Looking Back and Moving Ahead
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The American Board of Psychiatry and Neurology: Looking Back and Moving Ahead
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Movement Disorders specialist; clinical neurophysiologist; medical educator
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School of Medicine of the University of California, San Francisco (UCSF)
1855: 1813: 1712: 1427:"The results of surgical treatment for patients with a spinal angioma" 829: 745:"American Board of Psychiatry and Neurology, Inc., 2011 Annual Report" 583:
Handbook of Clinical Neurology, Volume 71: Systemic Diseases, Part III
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American Association of Neuromuscular & Electrodiagnostic Medicine
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Handbook of Clinical Neurology, Volume 70: Systemic Diseases, Part II
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Portuguese (Brazilian) translation published as a separate book, 1987
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Consultant in neurology and neurophysiology and Asst. Editor for the
599:. 4 Volumes. Academic Press, San Diego, 2003; Second edition, 2014 553:
Handbook of Clinical Neurology, Volume 63: Systemic Disease, Part 1
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from 1998 to 2007, was one of the two editors-in-chief (along with
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Victor Horsley: The World's First Neurosurgeon and His Conscience
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Victor Horsley: The World’s First Neurosurgeon and His Conscience
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Encyclopedia and Dictionary of Laboratory Medicine and Technology
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Royer Award (Neurology), University of California, San Francisco
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and related movement disorders. He retired in 2022 and lives in
1351:"The prognosis of patients with spinal vascular malformations" 18: 558:
Tollerud D, Aminoff MJ, et al.: "Veterans and Agent Orange,"
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Brown SĂ©quard: An Improbable Genius Who Transformed Medicine
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Brown-SĂ©quard: An Improbable Genius Who Transformed Medicine
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Children: Alexandra Robyn, Jonathan Charles, Anthony Thomas
516:. 2nd Edition (expanded). Churchill Livingstone: NY, 1987 910:. Washington, DC : American Psychiatric Pub., 2012" 326:, and is one of three series editors of the multivolume 641:, 4th Edition. Elsevier Academic Press, San Diego, 2024 613:. American Psychiatric Publishing, Washington, DC, 2012 535:. Churchill Livingstone: New York. First Edition, 1989 49: 39: 290:
from its inception in 1979 until he retired in 2022.
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UCSF Parkinson's Disease Clinic and Research Center
812:Muscle & Nerve; Editorial: Michael J. Aminoff. 227: 219: 211: 201: 187: 179: 162: 154: 146: 131: 123: 115: 101: 77: 16:
American clinical neurologist and neurophysiologist
1431:Journal of Neurology, Neurosurgery, and Psychiatry 1006:Journal of Neurology, Neurosurgery, and Psychiatry 616:Jones HR, Burns TM, Aminoff MJ, Pomeroy SL (Eds): 500:, Bennington JL (Ed), Saunders: Philadelphia, 1984 223:Electrophysiological studies of the nervous system 1934:British expatriate academics in the United States 491:Aminoff’s Electrodiagnosis in Clinical Neurology 1904:University of California, San Francisco faculty 425:A.B. Baker Award, American Academy of Neurology 906:"Aminoff, Michael J; Faulkner, Larry R (Eds): 639:Aminoff’s Diagnosis of Neuromuscular Disorders 256:whose later clinical work focused on treating 1909:University of California, San Francisco staff 634:, Cambridge University Press, Cambridge, 2022 569:Herbicide/Dioxin exposure and type 2 diabetes 166:Janette Dawn Aminoff (nee Williamson), wife. 8: 1831:Parkinson's Disease: Latest From the Experts 1684:: CS1 maint: multiple names: authors list ( 518:3rd Edition, Churchill Livingstone: NY, 1998 372:American Board of Psychiatry & Neurology 1425:Logue, V; Aminoff, MJ; Kendall, BE (1974). 1924:Fellows of the Royal College of Physicians 298:title of Distinguished Professor. He is a 279:University College Hospital Medical School 140:University College Hospital Medical School 88: 74: 1661: 1442: 1366: 1134: 1124: 1027: 1017: 948: 627:. Oxford University Press, New York, 2017 606:. Oxford University Press, New York, 2011 597:Encyclopedia of the Neurological Sciences 592:. 2 Volumes. Saunders, Philadelphia, 2002 503:Aminoff MJ (Ed): Electrodiagnosis issue, 324:Encyclopedia of the Neurological Sciences 300:Fellow of the Royal College of Physicians 689:"Michael Aminoff, MD, DSc, UCSF Profile" 539:Aminoff’s Neurology and General Medicine 666: 588:Brown WF, Bolton CF, Aminoff MJ (Eds): 551:Goetz CG, Tanner CM, Aminoff MJ (Eds): 480:. Addison Wesley: Reading, Mass., 1978 364:National Hospitals for Nervous Diseases 206:University of California, San Francisco 1677: 525:. Appleton & Lange: Norwalk, 1989. 485:Electrodiagnosis in Clinical Neurology 655:Parkinson's: Latest from the Experts. 546:Brown-SĂ©quard: A Visionary of Science 478:Electromyography in Clinical Practice 7: 1849:Parkinson's: Latest From the Experts 1392:Journal of the Neurological Sciences 1301:Journal of the Neurological Sciences 1053:Journal of the Neurological Sciences 651:Parkinson's Disease: A Dose of Hope. 521:Simon RP, Aminoff MJ, Greenberg DA: 487:. Churchill Livingstone: New York. 1807:Parkinson's Disease: A Dose of Hope 1789:Parkinson's Disease: A Dose of Hope 923:Aminoff, M. J; Sears, T. A (1971). 892:, Cambridge University Press, 2022" 1889:Alumni of the University of London 1701:Expert Review of Neurotherapeutics 1614:10.1212/01.wnl.0000312381.29287.ff 795:"Michael J. Aminoff, Publications" 14: 637:Ralph JW, Walker FO, Aminoff MJ: 308:American Neurological Association 1107:Aminoff, MJ; Wilcox, CS (1971). 874:, Oxford University Press, 2016" 856:, Oxford University Press, 1993" 277:in 1962 and as a physician from 23: 1851:Produced by UCTV, YouTube Link" 1809:Produced by UCTV, YouTube Link" 1349:Aminoff, MJ; Logue, V (1974). 941:10.1113/jphysiol.1971.sp009485 783:. McGraw-Hill Education. 2018. 609:Aminoff MJ, Faulkner L (Eds): 533:Neurology and General Medicine 507:. Saunders: Philadelphia, 1985 393:Handbook of Clinical Neurology 328:Handbook of Clinical Neurology 1: 595:Aminoff MJ, Daroff RB (Eds): 548:. Raven Press, New York, 1993 304:American Academy of Neurology 1833:Produced by UCTV, UCTV Link" 1791:Produced by UCTV, UCTV Link" 1757:10.1227/NEU.0b013e3181f53a5c 1654:10.1212/wnl.0b013e3181c29356 1404:10.1016/0022-510x(74)90229-9 1065:10.1016/0022-510x(80)90128-8 808:Aminoff, Michael J (2007). " 581:Aminoff MJ, Goetz CG (Eds): 574:Goetz CG, Aminoff MJ (Eds): 453:     447:     441:     435:     429:     423:     417:     411:     405:     302:of London as well as of the 1172:10.7326/0003-4819-108-6-791 1160:Annals of Internal Medicine 585:, Elsevier, Amsterdam, 1998 578:, Elsevier, Amsterdam, 1998 555:. Elsevier, Amsterdam, 1993 356:Royal College of Physicians 1950: 1929:People from Cambridgeshire 1899:British medical historians 1461:. Blackwells: Oxford, 1976 1196:Journal of Neurophysiology 1097:(London) 215:557-573, 1971 1208:10.1152/jn.1990.64.4.1270 929:The Journal of Physiology 567:. NAP, Washington, 1998; 473:. Blackwell: Oxford, 1976 275:University College London 262:San Francisco, California 248:, England) is a clinical 235: 172: 136:University College London 87: 1278:10.1093/brain/109.6.1103 1243:10.1093/brain/113.4.1075 562:. NAP, Washington, 1996; 1743:of Parkinson disease". 1113:British Medical Journal 810:A decade at the helm of 571:. NAP, Washington, 2000 330:published by Elsevier. 242:Michael Jeffrey Aminoff 79:Michael Jeffrey Aminoff 38:, as no other articles 1444:10.1136/jnnp.37.9.1074 1368:10.1093/brain/97.1.211 1328:10.1093/brain/97.1.197 646:Television appearances 541:); Sixth edition, 2021 368:Institute of Neurology 109:Little Paxton, England 96:by RCL Portrait Design 1571:10.1002/mus.880150909 1126:10.1136/bmj.4.5779.80 1095:Journal of Physiology 1019:10.1136/jnnp.42.7.649 888:"Michael J. Aminoff: 870:"Michael J. Aminoff: 852:"Michael J. Aminoff: 322:) of the four-volume 1914:British neurologists 1528:10.1212/wnl.42.3.627 1000:Aminoff, MJ (1979). 349:Education and career 288:Center of Excellence 1485:10.1212/wnl.39.1.80 1303:(23): 255–63. 1974. 258:Parkinson's disease 1713:10.1586/ern.10.161 818:Muscle & Nerve 814:Muscle & Nerve 523:Clinical Neurology 505:Neurologic Clinics 360:Middlesex Hospital 354:membership of the 335:C.E. Brown-SĂ©quard 57:for suggestions. 47:to this page from 1707:(12): 1839–1845. 1648:(20): 1662–1669. 1608:(21): 1980–1983. 830:10.1002/mus.20911 531:Aminoff MJ (Ed): 483:Aminoff MJ (Ed): 399:Honors and awards 254:neurophysiologist 239: 238: 155:Years active 71: 70: 1941: 1861: 1860: 1843: 1837: 1836: 1825: 1819: 1818: 1801: 1795: 1794: 1783: 1777: 1776: 1751:(5): 1377–1385. 1739: 1733: 1732: 1696: 1690: 1689: 1683: 1675: 1665: 1633: 1597: 1591: 1590: 1565:(9): 1045–1049. 1559:Muscle and Nerve 1554: 1548: 1547: 1511: 1505: 1504: 1468: 1462: 1455: 1449: 1448: 1446: 1437:(9): 1074–1081. 1422: 1416: 1415: 1387: 1381: 1380: 1370: 1346: 1340: 1339: 1311: 1305: 1304: 1296: 1290: 1289: 1272:(6): 1103–1113. 1261: 1255: 1254: 1237:(4): 1075–1091. 1226: 1220: 1219: 1202:(4): 1270–1281. 1190: 1184: 1183: 1155: 1149: 1148: 1138: 1128: 1104: 1098: 1091: 1085: 1084: 1059:(2–3): 213–219. 1048: 1042: 1041: 1031: 1021: 997: 991: 990: 983: 977: 976: 969: 963: 962: 952: 920: 914: 913: 902: 896: 895: 884: 878: 877: 866: 860: 859: 848: 842: 841: 805: 799: 798: 791: 785: 784: 772: 766: 765: 758: 752: 751: 749: 741: 735: 734: 727: 721: 720: 713: 707: 706: 699: 693: 692: 685: 679: 678: 671: 459: 454: 448: 442: 436: 430: 424: 418: 412: 406: 339:Sir Charles Bell 320:Robert B. Daroff 316:Muscle and Nerve 92: 75: 66: 63: 52: 50:related articles 27: 19: 1949: 1948: 1944: 1943: 1942: 1940: 1939: 1938: 1879: 1878: 1870: 1865: 1864: 1845: 1844: 1840: 1827: 1826: 1822: 1803: 1802: 1798: 1785: 1784: 1780: 1741: 1740: 1736: 1698: 1697: 1693: 1676: 1635: 1599: 1598: 1594: 1556: 1555: 1551: 1513: 1512: 1508: 1470: 1469: 1465: 1459:Spinal Angiomas 1456: 1452: 1424: 1423: 1419: 1389: 1388: 1384: 1348: 1347: 1343: 1313: 1312: 1308: 1298: 1297: 1293: 1263: 1262: 1258: 1228: 1227: 1223: 1192: 1191: 1187: 1157: 1156: 1152: 1119:(5779): 80–84. 1106: 1105: 1101: 1092: 1088: 1050: 1049: 1045: 999: 998: 994: 985: 984: 980: 971: 970: 966: 922: 921: 917: 904: 903: 899: 886: 885: 881: 868: 867: 863: 850: 849: 845: 807: 806: 802: 793: 792: 788: 774: 773: 769: 760: 759: 755: 747: 743: 742: 738: 729: 728: 724: 715: 714: 710: 701: 700: 696: 687: 686: 682: 673: 672: 668: 663: 648: 563: 536: 526: 517: 508: 488: 471:Spinal Angiomas 466: 457: 456: 452: 450: 446: 444: 440: 438: 434: 432: 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Little Paxton, England
University College London
University College Hospital Medical School
Neurology
Neurophysiology
University of California, San Francisco
Little Paxton
neurologist
neurophysiologist
Parkinson's disease
San Francisco, California
University College London
University College Hospital Medical School
School of Medicine of the University of California, San Francisco (UCSF)
Center of Excellence
American Association of Neuromuscular & Electrodiagnostic Medicine
Fellow of the Royal College of Physicians
American Academy of Neurology
American Neurological Association
Robert B. Daroff
C.E. Brown-SĂ©quard
Sir Charles Bell
Victor Horsley

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