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is named for
Michael Rossmann, Purdue's Hanley Distinguished Professor of Biological Sciences, who is a pioneer in employing high-performance computing in research to reveal the structure of viruses and their component protein molecules. Calculating electron density structure from X-ray
515:
When diagnosed with cancer, Rossmann moved into a retirement home, where he met and later married a staff member in charge of welcoming and hospitality, Karen Bogan. He was working on papers and grant proposals until shortly before his death.
324:
laboratory. He became full professor in 1967 and from 1978 held the chair of Hanley
Distinguished Professor of Biological Sciences at the university. He also held a joint appointment in the department of biochemistry and adjunct positions in
497:, also referred to as giant viruses. The determination of an atomic structure of Paramecium bursaria chlorella virus 1 that infects algae has opened up new possibilities for studying giant viruses at the atomic level.
1043:
Rossmann MG, Arnold E, Erickson JW, Frankenberger EA, Griffith JP, Hecht HJ, Johnson JE, Kamer G, Luo M, Mosser AG (1985). "Structure of a human common cold virus and functional relationship to other picornaviruses".
439:, which provided partial funding for the research, saw fit to organize a press conference, and the news travelled in the general press. This work laid the foundation for a molecular understanding of cell entry of
2726:
417:. Part of the problem was that it was very difficult at the time to produce milligram quantities of an animal virus, as needed for the X-ray crystallography. Rossmann pushed for the purchase by Purdue of a
2510:
613:
In 2016, he was awarded the
Raymond and Beverly Sackler International Prize in Biophysics for pioneering contributions to high-resolution diffraction analysis of atomic structures of proteins and viruses.
2505:
2731:
429:
the computer programs, calculations that had taken six weeks with the southern bean mosaic virus now took, for HRV14, only a fraction of a day. In 1985, he published his team's mapping in the journal
1337:
Yu IM, Zhang W, Holdaway HA, Li L, Kostyuchenko VA, Chipman PR, Kuhn RJ, Rossmann MG, Chen J (March 2008). "Structure of the immature dengue virus at low pH primes proteolytic maturation".
2561:
1214:
557:
2711:
1388:
Li L, Lok SM, Yu IM, Zhang Y, Kuhn RJ, Chen J, Rossmann MG (March 2008). "The flavivirus precursor membrane-envelope protein complex: structure and maturation".
2701:
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2379:
868:
Lipscomb WN, Robertson JM, Rossmann MG (1959). "518. Crystal-structure studies of polynuclear hydrocarbons. Part I. 2 : 3-8 : 9-dibenzoperylene".
260:
in 1953 where he taught physics in the technical college and received his Ph.D. in chemical crystallography in 1956. He attributes his initial interest in
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said of him, "Still vital, still curious, still in his lab at age 88, his was a life as rich in personal example as it was in scientific achievement."
2716:
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1239:
Kuhn RJ, Zhang W, Rossmann MG, Pletnev SV, Corver J, Lenches E, Jones CT, Mukhopadhyay S, Chipman PR, Strauss EG, Baker TS, Strauss JH (March 2002).
2721:
344:
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In 1964 Rossmann joined the faculty of the
Department of Biological Sciences at Purdue University as an associate professor. He directed the Purdue
656:
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2609:
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1197:
545:
2602:
2452:
2118:
1983:
1832:
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2490:
2186:
1180:
Rossmann MG, McKinlay MA, Xiao C (11 November 2010). "Chapter 16:Design of Capsid-binding
Antiviral Agents Against Human Rhinoviruses".
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161:
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2442:
2371:
1096:
348:
1631:
Fang Q, Zhu D, Agarkova I, Adhikari J, Klose T, Liu Y, Chen Z, Sun Y, Gross ML, Van Etten JL, Zhang X, Rossmann MG (January 2019).
2324:
1288:
Zhang W, Chipman PR, Corver J, Johnson PR, Zhang Y, Mukhopadhyay S, Baker TS, Strauss JH, Rossmann MG, Kuhn RJ (November 2003).
467:
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1993:
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1498:
Rossmann MG, Bernal R, Pletnev SV (December 2001). "Combining electron microscopic with x-ray crystallographic structures".
536:
crystallography results by
Rossmann's team had long been one of the larger tasks carried out on Purdue's computing systems.
512:
Rossmann's wife, Audrey, was a potter and artist. They had three children, Martin, Alice, and
Heather. Audrey died in 2009.
232:
protein motif. His most well recognised contribution to structural biology is the development of a phasing technique named
2447:
2437:
1742:
459:
311:
2219:
1215:"Researchers reveal Zika virus structure, a critical advance in the development of treatments - News - Purdue University"
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596:
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116:
891:
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2008:
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671:
580:
532:
479:
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Rossmann MG, Jacobson RA, Hirshfeld FL, Lipscomb WN (July 1959). "An account of some computing experiences".
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1988:
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67:
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1998:
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368:
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races on
Indiana lakes. He was very energetic, which sometimes caused difficulties for his team members.
271:
Rossmann began his career as a crystallographer when he became a student of J. Monteath
Robertson at the
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340:
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at the time. This work was made possible by more than one decade of studies on related mosquito borne
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2135:
1971:
1862:
1644:
1452:
1397:
1346:
1053:
842:
779:
Rossmann MG, Lipscomb WN (May 1958). "Molecular
Structure and Stereochemistry of an Iresin Diester".
745:
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375:
253:
79:
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568:
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Rossmann also had a long-term interest in complicated viral machines. These are exemplified by
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1241:"Structure of dengue virus: implications for flavivirus organization, maturation, and fusion"
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2013:
1946:
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490:
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343:, one of the largest early proteins to be solved. In 1973 his group found the structure of
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2003:
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217:
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Rao ST, Rossmann MG (May 1973). "Comparison of super-secondary structures in proteins".
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220:
physicist, microbiologist, and Hanley Distinguished Professor of Biological Sciences at
2199:
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2032:
1976:
1900:
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1559:
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1314:
1290:"Visualization of membrane protein domains by cryo-electron microscopy of dengue virus"
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1956:
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520:
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229:
98:
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Rossmann M (2014). "The study of virus structure and function: a personal history".
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1934:
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22:
996:"Proteopedia: Rossmann fold: A beta-alpha-beta fold at dinucleotide binding sites"
351:
was very similar to the one in the lactate dehydrogenase. This is now called the
2533:
2204:
2078:
1905:
1189:
918:"Michael G. Rossmann (1930–2019): Leadership in structural biology for 60 years"
610:
His own employer awarded him with the Purdue University Medal of Honor in 1995.
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444:
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387:
225:
124:
93:
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Proceedings of the National Academy of Sciences of the United States of America
2098:
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1441:"Dengue structure differs at the temperatures of its human and mosquito hosts"
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and for the development of capsid-binding inhibitors against a broad range of
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307:
303:
224:
who led a team of researchers to be the first to map the structure of a human
191:
519:
Rossmann died on 14 May 2019. Purdue president (and former Indiana governor)
275:. The title of his thesis was "A Study of Some Organic Crystal Structures".
1807:
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287:
249:
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Zhang X, Sheng J, Plevka P, Kuhn RJ, Diamond MS, Rossmann MG (April 2013).
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1021:
390:. This required developing new software and adapting existing software for
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282:, where he worked for two years as a post-doctoral fellow with Professor
792:
672:"The detection of sub-units within the crystallographic asymmetric unit"
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in 1996, and the Paul Ehrlich and Ludwig Darmstaedter Prize in 2001.
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364:
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Rossmann then turned to viruses, spending a sabbatical in 1971 with
1305:
2409:
1727:
347:, and Rossmann immediately realized that the binding site for the
1731:
806:
Rossmann MG, Lipscomb WN (1958). "The Sesquiterpenoid Iresin".
544:
Among other honors, Michael Rossmann was elected Fellow of the
450:
After the success with the first cold virus, work was done on
236:, which has led to about three quarters of depositions in the
21:
This article is about the microbiologist. For the boxer, see
657:"Renowned Purdue University scientist Michael Rossmann dies"
505:
Rossmann was an avid hiker and sailboat enthusiast, winning
462:, in 2016 his lab reported the first known structure of the
435:. The breakthrough nature of this result was such that the
252:, Germany, Rossmann studied physics and mathematics at the
290:, and writing computer programs for analysing structures.
286:, publishing on the structure of an Iresin Diester and a
2727:
Members of the United States National Academy of Sciences
2511:
Zeitschrift für Kristallographie – New Crystal Structures
2506:
Zeitschrift für Kristallographie – Crystalline Materials
386:. From 1972 to 1980 Rossmann and his team worked on the
16:
German-American physicist and microbiologist (1930–2019)
2732:
Foreign fellows of the Indian National Science Academy
2399:
256:, where he received BSc and MSc degrees. He moved to
892:"Michael Rossmann CV on Purdue University's web site"
723:
Biographical Memoirs of Fellows of the Royal Society
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2519:
2471:
2423:
2370:
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2031:
2022:
1945:
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American Association for the Advancement of Science
197:
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112:
89:
75:
56:
37:
30:
421:supercomputer, capable of delivering hundreds of
228:virus to an atomic level. He also discovered the
394:. It was found that this virus had a similar "
336:In 1970 his laboratory found the structure of
1743:
405:In the early 1980s Rossmann began working on
174:"A Study of Some Organic Crystal Structures"
8:
1535:"Structure and function of bacteriophage T4"
1122:"Virus Decoded; Feat May Help Prevent Colds"
1000:Biochemistry and Molecular Biology Education
2577:
2028:
1850:
1795:
1750:
1736:
1728:
911:
909:
907:
905:
903:
901:
382:, Sweden, working on the structure of the
329:'s Division of Biological Sciences and in
129:Paul Ehrlich and Ludwig Darmstaedter Prize
27:
1664:
1607:
1558:
1474:
1464:
1313:
1264:
1011:
943:
933:
870:Journal of the Chemical Society (Resumed)
698:
632:"Rossmann, M. G. (Michael G.), 1930-2019"
133:Sackler International Prize in Biophysics
1633:"Near-atomic structure of a giant virus"
1141:Rossmann MG, He Y, Kuhn RJ (July 2002).
781:Journal of the American Chemical Society
670:Rossmann MG, Blow DM (10 January 1962).
571:. He was awarded honorary doctorates by
345:Glyceraldehyde 3-phosphate dehydrogenase
725:. Vol. 21. 1976. pp. 447–484.
651:
649:
623:
298:Rossmann returned to the UK and to the
278:In 1956 he and his family moved to the
268:, whom he heard speak as a schoolboy.
2712:German emigrants to the United States
1533:Yap ML, Rossmann MG (December 2014).
595:, England; Institut Armand-Frappier,
546:American Academy of Arts and Sciences
7:
2702:Foreign members of the Royal Society
2644:
1984:Phase transformation crystallography
1143:"Picornavirus-receptor interactions"
1097:"Scientists map out common cold bug"
413:, one of the viruses that cause the
402:, which at the time was a surprise.
2692:Alumni of the University of Glasgow
2491:Journal of Chemical Crystallography
495:nucleocytoplasmic large DNA viruses
216:(30 July 1930 – 14 May 2019) was a
162:MRC Laboratory of Molecular Biology
1584:"Structure of large dsDNA viruses"
1582:Klose T, Rossmann MG (July 2014).
398:" to that found previously in the
14:
916:John (Jack) Johnson (July 2019).
2717:Immigrants to the United Kingdom
2697:21st-century American physicists
2643:
2632:
2631:
2238:
1701:
384:satellite tobacco necrosis virus
2722:Immigrants to the United States
1095:Boffey PM (12 September 1985).
552:in 1984, Foreign Member of the
315:Laboratory of Molecular Biology
310:as a research associate at the
2433:Bilbao Crystallographic Server
367:) that bind molecules such as
302:in 1958, where he worked with
1:
1500:Journal of Structural Biology
1257:10.1016/S0092-8674(02)00660-8
1159:10.1016/S0966-842X(02)02383-1
758:10.1088/0031-8949/89/9/098005
599:, Canada. He was awarded the
973:10.1016/0022-2836(73)90388-4
961:Journal of Molecular Biology
820:10.1016/0040-4020(58)80049-6
550:National Academy of Sciences
2481:Crystal Growth & Design
1773:Timeline of crystallography
1190:10.1039/9781849732239-00319
556:in 1996, and Fellow of the
437:National Science Foundation
2758:
2292:Nuclear magnetic resonance
1657:10.1038/s41467-019-08319-6
585:Vrije Universiteit Brussel
565:Louisa Gross Horwitz Prize
388:southern bean mosaic virus
117:Louisa Gross Horwitz Prize
20:
2687:Scientists from Frankfurt
2682:Purdue University faculty
2627:
2496:Journal of Crystal Growth
2236:
1294:Nature Structural Biology
855:10.1107/S0365110X59001591
709:10.1107/s0365110x62000067
478:, using a combination of
207:
138:
2737:People from Hesse-Nassau
2707:American microbiologists
2362:Single particle analysis
2220:Hermann–Mauguin notation
581:University of Strasbourg
563:In 1990, he was awarded
480:cryo-electron microscopy
460:cryo-electron microscopy
400:tomato bushy stunt virus
284:William N. Lipscomb, Jr.
188:William N. Lipscomb, Jr.
2486:Crystallography Reviews
2330:Isomorphous replacement
2124:Lomer–Cottrell junction
1466:10.1073/pnas.1304300110
1410:10.1126/science.1153263
1359:10.1126/science.1153264
554:Royal Society of London
548:in 1978, Member of the
333:'s school of medicine.
300:University of Cambridge
280:University of Minnesota
68:West Lafayette, Indiana
2742:American biophysicists
1999:Spinodal decomposition
1512:10.1006/jsbi.2002.4435
1147:Trends in Microbiology
835:Acta Crystallographica
679:Acta Crystallographica
527:Rossmann supercomputer
2539:Gregori Aminoff Prize
2335:Molecular replacement
1691:. Uppsala University.
1689:"Honorary doctorates"
1637:Nature Communications
1600:10.1515/hsz-2014-0145
1213:Purdue News Service.
601:Gregori Aminoff Prize
589:University of Glasgow
484:X-ray crystallography
341:lactate dehydrogenase
322:X-ray crystallography
273:University of Glasgow
234:molecular replacement
184:J. Monteath Robertson
121:Gregori Aminoff Prize
107:X-ray crystallography
103:molecular replacement
84:University of Glasgow
1845:Structure prediction
1588:Biological Chemistry
1184:. pp. 319–337.
1130:. 12 September 1985.
994:Hanukoglu I (2015).
878:10.1039/JR9590002601
659:. Purdue University.
597:University of Québec
466:, responsible for a
306:on the structure of
254:University of London
80:University of London
2109:Cottrell atmosphere
2089:Partial dislocation
1833:Restriction theorem
1649:2019NatCo..10..388F
1539:Future Microbiology
1457:2013PNAS..110.6795Z
1402:2008Sci...319.1830L
1351:2008Sci...319.1834Y
1182:Structural Virology
1058:1985Natur.317..145R
847:1959AcCry..12..530R
793:10.1021/ja01543a067
750:2014PhyS...89i8005R
691:1962AcCry..15...24R
634:. Purdue University
569:Columbia University
214:Michael G. Rossmann
2529:Carl Hermann Medal
2340:Molecular dynamics
2187:Defects in diamond
2182:Stone–Wales defect
1828:Reciprocal lattice
1790:Biocrystallography
1101:The New York Times
593:University of York
573:Uppsala University
392:Fourier transforms
331:Indiana University
327:Cornell University
51:Frankfurt, Germany
2659:
2658:
2623:
2622:
2230:Thermal ellipsoid
2195:
2194:
2104:Frank–Read source
2064:
2063:
1930:Aperiodic crystal
1896:
1895:
1778:Crystallographers
1551:10.2217/fmb.14.91
1199:978-0-85404-171-8
1127:Los Angeles Times
1013:10.1002/bmb.20849
540:Awards and honors
355:. It is found in
266:Kathleen Lonsdale
238:Protein Data Bank
222:Purdue University
211:
210:
198:Doctoral students
180:Academic advisors
158:Purdue University
140:Scientific career
2749:
2647:
2646:
2635:
2634:
2578:
2501:Kristallografija
2355:Gerchberg–Saxton
2250:Characterisation
2242:
2225:Structure factor
2029:
2014:Ostwald ripening
1851:
1796:
1752:
1745:
1738:
1729:
1719:Michael Rossmann
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1430:
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1396:(5871): 1830–4.
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1379:
1378:
1345:(5871): 1834–7.
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1066:10.1038/317145a0
1052:(6033): 145–53.
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991:
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956:
950:
949:
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937:
935:10.1002/pro.3671
928:(9): 1538–1544.
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533:Rossmann cluster
501:Life and hobbies
491:bacteriophage T4
63:
47:
45:
32:Michael Rossmann
28:
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2752:
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2515:
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2419:
2390:CrystalExplorer
2366:
2350:Phase retrieval
2313:
2244:
2243:
2234:
2191:
2170:Schottky defect
2069:Perfect crystal
2060:
2056:Abnormal growth
2018:
2004:Supersaturation
1967:Miscibility gap
1948:
1941:
1892:
1849:
1813:Bravais lattice
1794:
1761:
1759:Crystallography
1756:
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1706:
1702:
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1581:
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1545:(12): 1319–27.
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1037:
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922:Protein Science
915:
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890:
889:
885:
867:
866:
862:
832:
831:
827:
814:(3–4): 275–93.
805:
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778:
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773:
738:Physica Scripta
735:
734:
730:
721:
720:
716:
700:10.1.1.319.3019
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655:
654:
647:
637:
635:
630:
629:
625:
620:
542:
529:
503:
468:severe epidemic
396:jelly roll fold
376:Bror Strandberg
296:
262:crystallography
246:
218:German-American
190:
186:
160:
131:
127:
123:
119:
105:
101:
97:
96:virus structure
82:
76:Alma mater
71:
65:
61:
52:
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43:
41:
33:
26:
17:
12:
11:
5:
2755:
2753:
2745:
2744:
2739:
2734:
2729:
2724:
2719:
2714:
2709:
2704:
2699:
2694:
2689:
2684:
2679:
2674:
2664:
2663:
2657:
2656:
2654:
2653:
2641:
2628:
2625:
2624:
2621:
2620:
2618:
2617:
2612:
2607:
2606:
2605:
2600:
2595:
2584:
2582:
2575:
2574:
2569:
2564:
2559:
2553:
2551:
2545:
2544:
2542:
2541:
2536:
2531:
2525:
2523:
2517:
2516:
2514:
2513:
2508:
2503:
2498:
2493:
2488:
2483:
2477:
2475:
2469:
2468:
2466:
2465:
2460:
2455:
2450:
2445:
2440:
2435:
2429:
2427:
2421:
2420:
2418:
2417:
2412:
2407:
2402:
2397:
2392:
2387:
2382:
2376:
2374:
2368:
2367:
2365:
2364:
2359:
2358:
2357:
2347:
2342:
2337:
2332:
2327:
2325:Direct methods
2321:
2319:
2315:
2314:
2312:
2311:
2310:
2309:
2304:
2294:
2289:
2288:
2287:
2282:
2272:
2271:
2270:
2265:
2254:
2252:
2246:
2245:
2237:
2235:
2233:
2232:
2227:
2222:
2217:
2212:
2210:Ewald's sphere
2207:
2202:
2196:
2193:
2192:
2190:
2189:
2184:
2179:
2178:
2177:
2172:
2162:
2161:
2160:
2155:
2153:Frenkel defect
2150:
2148:Bjerrum defect
2140:
2139:
2138:
2128:
2127:
2126:
2121:
2116:
2114:Peierls stress
2111:
2106:
2101:
2096:
2091:
2086:
2084:Burgers vector
2076:
2074:Stacking fault
2071:
2065:
2062:
2061:
2059:
2058:
2053:
2048:
2043:
2037:
2035:
2033:Grain boundary
2026:
2020:
2019:
2017:
2016:
2011:
2006:
2001:
1996:
1991:
1986:
1981:
1980:
1979:
1977:Liquid crystal
1974:
1969:
1964:
1953:
1951:
1943:
1942:
1940:
1939:
1938:
1937:
1927:
1926:
1925:
1915:
1914:
1913:
1908:
1897:
1894:
1893:
1891:
1890:
1885:
1880:
1875:
1870:
1865:
1859:
1857:
1848:
1847:
1842:
1840:Periodic table
1837:
1836:
1835:
1830:
1825:
1820:
1815:
1804:
1802:
1793:
1792:
1787:
1782:
1781:
1780:
1769:
1767:
1763:
1762:
1757:
1755:
1754:
1747:
1740:
1732:
1707:
1700:
1699:
1698:
1695:
1694:
1680:
1623:
1594:(7–8): 711–9.
1574:
1525:
1506:(3): 190–200.
1490:
1451:(17): 6795–9.
1431:
1380:
1329:
1306:10.1038/nsb990
1300:(11): 907–12.
1280:
1231:
1219:www.purdue.edu
1205:
1198:
1172:
1133:
1113:
1087:
1035:
986:
951:
897:
883:
860:
825:
798:
787:(10): 2592–3.
771:
728:
714:
662:
645:
622:
621:
619:
616:
541:
538:
528:
525:
502:
499:
407:picornaviruses
361:dehydrogenases
295:
292:
245:
242:
209:
208:
205:
204:
199:
195:
194:
181:
177:
176:
171:
165:
164:
155:
151:
150:
147:
143:
142:
136:
135:
114:
110:
109:
91:
90:Known for
87:
86:
77:
73:
72:
66:
64:(aged 88)
58:
54:
53:
50:
39:
35:
34:
31:
15:
13:
10:
9:
6:
4:
3:
2:
2754:
2743:
2740:
2738:
2735:
2733:
2730:
2728:
2725:
2723:
2720:
2718:
2715:
2713:
2710:
2708:
2705:
2703:
2700:
2698:
2695:
2693:
2690:
2688:
2685:
2683:
2680:
2678:
2675:
2673:
2670:
2669:
2667:
2652:
2651:
2642:
2640:
2639:
2630:
2629:
2626:
2616:
2613:
2611:
2608:
2604:
2601:
2599:
2596:
2594:
2591:
2590:
2589:
2586:
2585:
2583:
2579:
2573:
2570:
2568:
2565:
2563:
2560:
2558:
2555:
2554:
2552:
2550:
2546:
2540:
2537:
2535:
2532:
2530:
2527:
2526:
2524:
2522:
2518:
2512:
2509:
2507:
2504:
2502:
2499:
2497:
2494:
2492:
2489:
2487:
2484:
2482:
2479:
2478:
2476:
2474:
2470:
2464:
2461:
2459:
2456:
2454:
2451:
2449:
2446:
2444:
2441:
2439:
2436:
2434:
2431:
2430:
2428:
2426:
2422:
2416:
2413:
2411:
2408:
2406:
2403:
2401:
2398:
2396:
2393:
2391:
2388:
2386:
2383:
2381:
2378:
2377:
2375:
2373:
2369:
2363:
2360:
2356:
2353:
2352:
2351:
2348:
2346:
2345:Patterson map
2343:
2341:
2338:
2336:
2333:
2331:
2328:
2326:
2323:
2322:
2320:
2316:
2308:
2305:
2303:
2300:
2299:
2298:
2295:
2293:
2290:
2286:
2283:
2281:
2278:
2277:
2276:
2273:
2269:
2266:
2264:
2261:
2260:
2259:
2256:
2255:
2253:
2251:
2247:
2241:
2231:
2228:
2226:
2223:
2221:
2218:
2216:
2215:Friedel's law
2213:
2211:
2208:
2206:
2203:
2201:
2198:
2197:
2188:
2185:
2183:
2180:
2176:
2173:
2171:
2168:
2167:
2166:
2163:
2159:
2158:Wigner effect
2156:
2154:
2151:
2149:
2146:
2145:
2144:
2143:Interstitials
2141:
2137:
2134:
2133:
2132:
2129:
2125:
2122:
2120:
2117:
2115:
2112:
2110:
2107:
2105:
2102:
2100:
2097:
2095:
2092:
2090:
2087:
2085:
2082:
2081:
2080:
2077:
2075:
2072:
2070:
2067:
2066:
2057:
2054:
2052:
2049:
2047:
2044:
2042:
2039:
2038:
2036:
2034:
2030:
2027:
2025:
2021:
2015:
2012:
2010:
2007:
2005:
2002:
2000:
1997:
1995:
1992:
1990:
1989:Precipitation
1987:
1985:
1982:
1978:
1975:
1973:
1970:
1968:
1965:
1963:
1960:
1959:
1958:
1957:Phase diagram
1955:
1954:
1952:
1950:
1944:
1936:
1933:
1932:
1931:
1928:
1924:
1921:
1920:
1919:
1916:
1912:
1909:
1907:
1904:
1903:
1902:
1899:
1898:
1889:
1886:
1884:
1881:
1879:
1876:
1874:
1871:
1869:
1866:
1864:
1861:
1860:
1858:
1856:
1852:
1846:
1843:
1841:
1838:
1834:
1831:
1829:
1826:
1824:
1821:
1819:
1816:
1814:
1811:
1810:
1809:
1806:
1805:
1803:
1801:
1797:
1791:
1788:
1786:
1783:
1779:
1776:
1775:
1774:
1771:
1770:
1768:
1764:
1760:
1753:
1748:
1746:
1741:
1739:
1734:
1733:
1730:
1722:
1721:
1720:
1714:
1710:
1690:
1684:
1681:
1676:
1672:
1667:
1662:
1658:
1654:
1650:
1646:
1642:
1638:
1634:
1627:
1624:
1619:
1615:
1610:
1605:
1601:
1597:
1593:
1589:
1585:
1578:
1575:
1570:
1566:
1561:
1556:
1552:
1548:
1544:
1540:
1536:
1529:
1526:
1521:
1517:
1513:
1509:
1505:
1501:
1494:
1491:
1486:
1482:
1477:
1472:
1467:
1462:
1458:
1454:
1450:
1446:
1442:
1435:
1432:
1427:
1423:
1419:
1415:
1411:
1407:
1403:
1399:
1395:
1391:
1384:
1381:
1376:
1372:
1368:
1364:
1360:
1356:
1352:
1348:
1344:
1340:
1333:
1330:
1325:
1321:
1316:
1311:
1307:
1303:
1299:
1295:
1291:
1284:
1281:
1276:
1272:
1267:
1262:
1258:
1254:
1251:(5): 717–25.
1250:
1246:
1242:
1235:
1232:
1220:
1216:
1209:
1206:
1201:
1195:
1191:
1187:
1183:
1176:
1173:
1168:
1164:
1160:
1156:
1153:(7): 324–31.
1152:
1148:
1144:
1137:
1134:
1129:
1128:
1123:
1117:
1114:
1102:
1098:
1091:
1088:
1083:
1079:
1075:
1071:
1067:
1063:
1059:
1055:
1051:
1047:
1039:
1036:
1031:
1027:
1023:
1019:
1014:
1009:
1005:
1001:
997:
990:
987:
982:
978:
974:
970:
967:(2): 241–56.
966:
962:
955:
952:
946:
941:
936:
931:
927:
923:
919:
912:
910:
908:
906:
904:
902:
898:
893:
887:
884:
879:
875:
871:
864:
861:
856:
852:
848:
844:
840:
836:
829:
826:
821:
817:
813:
809:
802:
799:
794:
790:
786:
782:
775:
772:
767:
763:
759:
755:
751:
747:
744:(9): 241–56.
743:
739:
732:
729:
724:
718:
715:
710:
706:
701:
696:
692:
688:
684:
680:
673:
666:
663:
658:
652:
650:
646:
633:
627:
624:
617:
615:
611:
608:
606:
603:in 1994, the
602:
598:
594:
590:
586:
582:
578:
574:
570:
566:
561:
559:
555:
551:
547:
539:
537:
534:
526:
524:
522:
521:Mitch Daniels
517:
513:
510:
508:
500:
498:
496:
492:
487:
485:
481:
477:
473:
469:
465:
461:
457:
453:
448:
446:
445:enteroviruses
442:
441:enteroviruses
438:
434:
433:
428:
424:
420:
416:
412:
408:
403:
401:
397:
393:
389:
385:
381:
377:
372:
371:or NAD/NADH.
370:
366:
362:
358:
354:
353:Rossmann fold
350:
346:
342:
339:
334:
332:
328:
323:
318:
316:
313:
309:
305:
301:
293:
291:
289:
285:
281:
276:
274:
269:
267:
263:
259:
255:
251:
243:
241:
239:
235:
231:
230:Rossmann fold
227:
223:
219:
215:
206:
203:
200:
196:
193:
189:
185:
182:
178:
175:
172:
170:
166:
163:
159:
156:
152:
148:
144:
141:
137:
134:
130:
126:
122:
118:
115:
111:
108:
104:
100:
99:Rossmann fold
95:
92:
88:
85:
81:
78:
74:
69:
59:
55:
40:
36:
29:
24:
19:
2648:
2636:
2581:Associations
2549:Organisation
2041:Disclination
1972:Polymorphism
1935:Quasicrystal
1878:Orthorhombic
1818:Miller index
1766:Key concepts
1717:
1716:
1715:profile for
1712:
1683:
1640:
1636:
1626:
1591:
1587:
1577:
1542:
1538:
1528:
1503:
1499:
1493:
1448:
1444:
1434:
1393:
1389:
1383:
1342:
1338:
1332:
1297:
1293:
1283:
1248:
1244:
1234:
1222:. Retrieved
1218:
1208:
1181:
1175:
1150:
1146:
1136:
1125:
1116:
1106:12 September
1104:. Retrieved
1100:
1090:
1049:
1045:
1038:
1006:(3): 206–9.
1003:
999:
989:
964:
960:
954:
925:
921:
886:
869:
863:
841:(7): 530–5.
838:
834:
828:
811:
807:
801:
784:
780:
774:
741:
737:
731:
722:
717:
685:(1): 24–31.
682:
678:
665:
636:. Retrieved
626:
612:
609:
591:, Scotland;
579:(1983); the
562:
543:
530:
518:
514:
511:
504:
488:
476:dengue virus
474:, including
472:flaviviruses
456:flaviviruses
452:alphaviruses
449:
430:
409:, and chose
404:
373:
335:
319:
297:
277:
270:
247:
213:
212:
173:
154:Institutions
139:
62:(2019-05-14)
48:30 July 1930
23:Mike Rossman
18:
2677:1930 births
2672:2019 deaths
2534:Ewald Prize
2302:Diffraction
2280:Diffraction
2263:Diffraction
2205:Bragg plane
2200:Bragg's law
2079:Dislocation
1994:Segregation
1906:Crystallite
1823:Point group
808:Tetrahedron
605:Ewald Prize
587:, Belgium;
427:vectorizing
415:common cold
226:common cold
125:Ewald Prize
94:common cold
60:14 May 2019
2666:Categories
2318:Algorithms
2307:Scattering
2285:Scattering
2268:Scattering
2136:Slip bands
2099:Cross slip
1949:transition
1883:Tetragonal
1873:Monoclinic
1785:Metallurgy
1643:(1): 388.
638:27 January
618:References
583:, France;
464:Zika virus
308:hemoglobin
304:Max Perutz
202:Ping Zhang
192:Max Perutz
149:Biophysics
44:1930-07-30
2425:Databases
1888:Triclinic
1868:Hexagonal
1808:Unit cell
1800:Structure
695:CiteSeerX
560:in 1999.
507:M-16 Scow
423:megaflops
419:Cyber 205
359:(such as
288:terpenoid
250:Frankfurt
244:Education
2638:Category
2473:Journals
2405:OctaDist
2400:JANA2020
2372:Software
2258:Electron
2175:F-center
1962:Eutectic
1923:Fiveling
1918:Twinning
1911:Equiaxed
1675:30674888
1618:25003382
1569:25517898
1520:12051899
1485:23569243
1426:37643601
1418:18369147
1375:42267698
1367:18369148
1324:14528291
1275:11893341
1167:12110211
1030:11857160
1022:25704928
872:: 2601.
458:. Using
425:. After
248:Born in
2650:Commons
2598:Germany
2275:Neutron
2165:Vacancy
2024:Defects
2009:GP-zone
1855:Systems
1711:has an
1709:Scholia
1666:6344570
1645:Bibcode
1609:4307781
1560:4275845
1476:3637732
1453:Bibcode
1398:Bibcode
1390:Science
1347:Bibcode
1339:Science
1315:4148076
1266:4152842
1082:4288590
1074:2993920
1054:Bibcode
981:4737475
945:6699092
843:Bibcode
766:3925904
746:Bibcode
687:Bibcode
380:Uppsala
365:kinases
357:enzymes
338:dogfish
258:Glasgow
2593:France
2588:Europe
2521:Awards
2051:Growth
1901:Growth
1713:author
1673:
1663:
1616:
1606:
1567:
1557:
1518:
1483:
1473:
1424:
1416:
1373:
1365:
1322:
1312:
1273:
1263:
1224:14 May
1196:
1165:
1080:
1072:
1046:Nature
1028:
1020:
979:
942:
764:
697:
577:Sweden
432:Nature
294:Career
169:Thesis
146:Fields
113:Awards
70:, U.S.
2615:Japan
2562:IOBCr
2415:SHELX
2410:Olex2
2297:X-ray
1947:Phase
1863:Cubic
1422:S2CID
1371:S2CID
1078:S2CID
1026:S2CID
762:S2CID
675:(PDF)
567:from
411:HRV14
2557:IUCr
2458:ICDD
2453:ICSD
2438:CCDC
2385:Coot
2380:CCP4
2131:Slip
2094:Kink
1671:PMID
1614:PMID
1565:PMID
1516:PMID
1481:PMID
1414:PMID
1363:PMID
1320:PMID
1271:PMID
1245:Cell
1226:2019
1194:ISBN
1163:PMID
1108:2006
1070:PMID
1018:PMID
977:PMID
640:2021
531:The
493:and
486:.
482:and
454:and
57:Died
38:Born
2572:DMG
2567:RAS
2463:PDB
2448:COD
2443:CIF
2395:DSR
2119:GND
2046:CSL
1661:PMC
1653:doi
1604:PMC
1596:doi
1592:395
1555:PMC
1547:doi
1508:doi
1504:136
1471:PMC
1461:doi
1449:110
1406:doi
1394:319
1355:doi
1343:319
1310:PMC
1302:doi
1261:PMC
1253:doi
1249:108
1186:doi
1155:doi
1062:doi
1050:317
1008:doi
969:doi
940:PMC
930:doi
874:doi
851:doi
816:doi
789:doi
754:doi
705:doi
378:in
369:ATP
363:or
349:NAD
312:MRC
264:to
2668::
2610:US
2603:UK
1669:.
1659:.
1651:.
1641:10
1639:.
1635:.
1612:.
1602:.
1590:.
1586:.
1563:.
1553:.
1541:.
1537:.
1514:.
1502:.
1479:.
1469:.
1459:.
1447:.
1443:.
1420:.
1412:.
1404:.
1392:.
1369:.
1361:.
1353:.
1341:.
1318:.
1308:.
1298:10
1296:.
1292:.
1269:.
1259:.
1247:.
1243:.
1217:.
1192:.
1161:.
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